LOCUS       NZ_CP059694.1          10801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP059694.1 Gordonia rubripertincta strain SD5 chromosome,
            complete genome.
ACCESSION   NZ_CP059694
VERSION     NZ_CP059694.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:22:50
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 767300
            Orig. end    :: 778101
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10801
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[772300:773101](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5801
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10801
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10801
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             618..2096
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105:amidase (Score: 399.5; E-value: 3.4e-121)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_699"
                     /transl_table=11
                     /translation="MGEYLGADATALAGLVASGEVTAAELLDLARARAAAVNPDLNAIV
                     IPIEAEADHRARTELTGPFAGVPFLIKDLAQDYRGYPTTRGSRSLARHVATEHATVVQR
                     FLDAGLVVFGKTNTPEFGSKAITESVLWGPARNPWNLDVTPGGSSGGSAAAVAAGVVPA
                     AGANDGGGSIRIPAACTGLVGLKASRGLMPFGPATGEPLFGMGVEGVVTRTVRDAAALY
                     DAIIGPTASSTYPAPLHTESFTTRIASPPRLLRIGYTTRSAINPAPHPEAVAAVEHAAK
                     LLTELGHQVDEVDPPHDDAELARDFLEIWFAKAAAQVDEARRLSGAGDADFEADTLALA
                     EIGRAAGVVPLFRALDHVNHHVRALERFHETHDLLLTPTLAVPPPAVGSMTTPPLLQQA
                     ARLAARARIGKVMSRVGIVDQLVEENLGWVPYTQLANMTGRPAISVPLHWTGTGLPLGV
                     QFVGRLGADGDLLALAASLEDAAPWFHRYADISI"
     PFAM_domain     693..2030
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_699_0179"
                     /evalue="8.90E-87"
                     /label="ctg1_699"
                     /locus_tag="ctg1_699"
                     /protein_end="471"
                     /protein_start="25"
                     /score="292.0"
                     /tool="antismash"
                     /translation="LLDLARARAAAVNPDLNAIVIPIEAEADHRARTELTGPFAGVPFL
                     IKDLAQDYRGYPTTRGSRSLARHVATEHATVVQRFLDAGLVVFGKTNTPEFGSKAITES
                     VLWGPARNPWNLDVTPGGSSGGSAAAVAAGVVPAAGANDGGGSIRIPAACTGLVGLKAS
                     RGLMPFGPATGEPLFGMGVEGVVTRTVRDAAALYDAIIGPTASSTYPAPLHTESFTTRI
                     ASPPRLLRIGYTTRSAINPAPHPEAVAAVEHAAKLLTELGHQVDEVDPPHDDAELARDF
                     LEIWFAKAAAQVDEARRLSGAGDADFEADTLALAEIGRAAGVVPLFRALDHVNHHVRAL
                     ERFHETHDLLLTPTLAVPPPAVGSMTTPPLLQQAARLAARARIGKVMSRVGIVDQLVEE
                     NLGWVPYTQLANMTGRPAISVPLHWTGTGLPLGVQFVGRLGADGDLL"
     CDS             2172..3833
                     /locus_tag="ctg1_700"
                     /transl_table=11
                     /translation="VTKQVADAVVVGAGLAGLVATYELTKAGRRVVVVDQENRKNLGGQ
                     AFWSLGGLFMVDTPEQRRLGITDSADLALQDWMGSAGFDRDDEDYWPRQWARAYVDFAA
                     TEKRQYLHDLGLRITPIVGWAERGGGFADGHGNSVPRFHLTWGTGPEVVRIFAEPVLEA
                     EKRGLVEFQFRHRVDELVVEDGAAVGVRGATLAPTDLDRGKASNRDVVGDFEIRAGAVI
                     VTSGGIGHNHDLIRKNWPVDRLGPAPKTMISGVPAHVDGRMLEISEDAGANIVNRDRMW
                     HYTEGIHNWDPIWPDHAIRIIPGPSSLWLDANGNRLAPPNFPGFDTNSTMKAILAAGHD
                     YSWFILTQSIVEKEFMLSGSEQNPDITSKDLKLAAKSRLAKGAPGPVDAFVRNGIDFVV
                     ADNLPELVSGMNAIARGPELDLAHIERVISARDAEVENKFSKDAQLMAINNARQFIGDR
                     IVRVAKPHRILDPTHGPLIAVRLNILTRKTLGGLETNLDSQVLRPDGSAFDGLFAAGEV
                     AGFGGGGVHGYNALEGTFLGGCIFSGRAAGRAVARS"
     PFAM_domain     2190..3779
                     /aSDomain="FAD_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00890.26"
                     /description="FAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_700_0180"
                     /evalue="1.50E-109"
                     /label="ctg1_700"
                     /locus_tag="ctg1_700"
                     /protein_end="536"
                     /protein_start="6"
                     /score="367.0"
                     /tool="antismash"
                     /translation="DAVVVGAGLAGLVATYELTKAGRRVVVVDQENRKNLGGQAFWSLG
                     GLFMVDTPEQRRLGITDSADLALQDWMGSAGFDRDDEDYWPRQWARAYVDFAATEKRQY
                     LHDLGLRITPIVGWAERGGGFADGHGNSVPRFHLTWGTGPEVVRIFAEPVLEAEKRGLV
                     EFQFRHRVDELVVEDGAAVGVRGATLAPTDLDRGKASNRDVVGDFEIRAGAVIVTSGGI
                     GHNHDLIRKNWPVDRLGPAPKTMISGVPAHVDGRMLEISEDAGANIVNRDRMWHYTEGI
                     HNWDPIWPDHAIRIIPGPSSLWLDANGNRLAPPNFPGFDTNSTMKAILAAGHDYSWFIL
                     TQSIVEKEFMLSGSEQNPDITSKDLKLAAKSRLAKGAPGPVDAFVRNGIDFVVADNLPE
                     LVSGMNAIARGPELDLAHIERVISARDAEVENKFSKDAQLMAINNARQFIGDRIVRVAK
                     PHRILDPTHGPLIAVRLNILTRKTLGGLETNLDSQVLRPDGSAFDGLFAAGEVAGFGGG
                     GVHGYNALEGTFL"
     CDS             3947..4951
                     /locus_tag="ctg1_701"
                     /transl_table=11
                     /translation="VPVPQTILTRKTKSAIFLVLTINDGGEDTVRDVLEEIPGLNNAVS
                     SRAPEAALAGIVSIGSDAWDRLFDGPRPRSLRPFVPYEGAVHTAPATPADLLVHIKSDQ
                     MDLCFELGRLITDALGDAVTVVDEVHGFRYFDLRDLIGFVDGTENPVGQAAIDAITVGD
                     EDPDFAGGSYVAIQRYVHDLSSWNDLSTSEQEAAIGRTKLDNVEMSDDVKPPNSHIALN
                     KVEDENGEEIDVVRDNMPYGDVSGNGENGTFYIAYSAGPDVTEEMLRKMFIGDPPGTYD
                     RLLDFTTAVTGSQFFTPTLDFLEDLPPAPGAAEPAAQTPVRRADGSLGIGSLH"
     aSDomain        3959..4852
                     /aSDomain="TIGR01413"
                     /aSTool="tigrfam"
                     /description="Dyp_perox_fam: Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_701_0047"
                     /evalue="6.60E-79"
                     /identifier="TIGR01413"
                     /label="ctg1_701"
                     /locus_tag="ctg1_701"
                     /protein_end="302"
                     /protein_start="4"
                     /score="263.5"
                     /tool="antismash"
                     /translation="QTILTRKTKSAIFLVLTINDGGEDTVRDVLEEIPGLNNAVSSRAP
                     EAALAGIVSIGSDAWDRLFDGPRPRSLRPFVPYEGAVHTAPATPADLLVHIKSDQMDLC
                     FELGRLITDALGDAVTVVDEVHGFRYFDLRDLIGFVDGTENPVGQAAIDAITVGDEDPD
                     FAGGSYVAIQRYVHDLSSWNDLSTSEQEAAIGRTKLDNVEMSDDVKPPNSHIALNKVED
                     ENGEEIDVVRDNMPYGDVSGNGENGTFYIAYSAGPDVTEEMLRKMFIGDPPGTYDRLLD
                     FTTAVTGSQFFTPTLDF"
     PFAM_domain     3959..4852
                     /aSDomain="Dyp_perox"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04261.14"
                     /description="Dyp-type peroxidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_701_0181"
                     /evalue="2.80E-84"
                     /label="ctg1_701"
                     /locus_tag="ctg1_701"
                     /protein_end="302"
                     /protein_start="4"
                     /score="283.0"
                     /tool="antismash"
                     /translation="QTILTRKTKSAIFLVLTINDGGEDTVRDVLEEIPGLNNAVSSRAP
                     EAALAGIVSIGSDAWDRLFDGPRPRSLRPFVPYEGAVHTAPATPADLLVHIKSDQMDLC
                     FELGRLITDALGDAVTVVDEVHGFRYFDLRDLIGFVDGTENPVGQAAIDAITVGDEDPD
                     FAGGSYVAIQRYVHDLSSWNDLSTSEQEAAIGRTKLDNVEMSDDVKPPNSHIALNKVED
                     ENGEEIDVVRDNMPYGDVSGNGENGTFYIAYSAGPDVTEEMLRKMFIGDPPGTYDRLLD
                     FTTAVTGSQFFTPTLDF"
     PFAM_domain     5001..5753
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_702_0182"
                     /evalue="1.70E-93"
                     /label="ctg1_702"
                     /locus_tag="ctg1_702"
                     /protein_end="251"
                     /protein_start="0"
                     /score="312.7"
                     /tool="antismash"
                     /translation="MNNLHRELAPISEAAWAEIEEEATRSFKRNIAGRRLVDVKGPMGQ
                     DTAAVTLGHRSKIDSPADGIQAFIRRTQSLVELKVPFTVSREAIDDVDRGAQDSDWDPV
                     VEAARQLALAEDRAIFEGYAAASISGIRAEATATPIQLPEDVRDYPEAVSQALTTLRLA
                     SVDGPYSVAMSAEVYTQVNETSNHGYPIRQHIQRLLDGDIVWAPAIRGAFVMSTRGGDF
                     ELTIGQDVSIGYDSHDADVVNLYFQESFT"
     CDS             5001..5801
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_702"
                     /sec_met_domain="Linocin_M18 (E-value: 6.5e-95, bitscore:
                     315.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLHRELAPISEAAWAEIEEEATRSFKRNIAGRRLVDVKGPMGQ
                     DTAAVTLGHRSKIDSPADGIQAFIRRTQSLVELKVPFTVSREAIDDVDRGAQDSDWDPV
                     VEAARQLALAEDRAIFEGYAAASISGIRAEATATPIQLPEDVRDYPEAVSQALTTLRLA
                     SVDGPYSVAMSAEVYTQVNETSNHGYPIRQHIQRLLDGDIVWAPAIRGAFVMSTRGGDF
                     ELTIGQDVSIGYDSHDADVVNLYFQESFTYLTHTGEAAVALFGG"
     CDS             5865..7598
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 380.9; E-value:
                     1.7e-115)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_703"
                     /transl_table=11
                     /translation="MLTRLISTYLQRYRINIVLVVTLQFVATAAMLYLPSLNADIIDNG
                     VATGDTGYIMRIGGWMLLVSIVQIVATIIAQFFGSRAALGVGRDIRSDLLHRVNSFSAR
                     EVGTFGAPSLITRTTNDVQQVQMLIVMCSAILVMAPIMCIGGIVMGIREAPALSWVIAI
                     AVPILGLAMGLVIARMIPGFRAMQERIDSVNRVLREQITGIRVVRAFVREEHERKRFAV
                     ANDHLADATLRVGKLMALMFPLVMVITNVTIVAVIWFGGHAVSDGTVEIGALTALMSYV
                     MQILMSVMMASFLAMMAPRAAVCAERITEVLDTETSVHPPVDPIGFAGHPGTVKFDAAE
                     FRYPGADDPVLSGISFEVTPGTTTAIVGSTGSGKTTLLGLVPRLIDATEGKVSVGGTDV
                     KRLDPDELRSVVGLVPQRPYLFSGTIRSNILHGKSDATDDEIWEALRIAQADEFVSAMP
                     DGLDTHVAQGGTTVSGGQRQRLAIARALVRRPAVYLFDDSFSALDLTTDAKLRAALRPA
                     TRDASVIVVAQRISTIVDAEQIVVLDRGRIVGIGTHDDLLASCPTYAEIAESQLAMEER
                     A"
     PFAM_domain     5916..6728
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_703_0183"
                     /evalue="1.80E-43"
                     /label="ctg1_703"
                     /locus_tag="ctg1_703"
                     /protein_end="288"
                     /protein_start="17"
                     /score="149.3"
                     /tool="antismash"
                     /translation="VLVVTLQFVATAAMLYLPSLNADIIDNGVATGDTGYIMRIGGWML
                     LVSIVQIVATIIAQFFGSRAALGVGRDIRSDLLHRVNSFSAREVGTFGAPSLITRTTND
                     VQQVQMLIVMCSAILVMAPIMCIGGIVMGIREAPALSWVIAIAVPILGLAMGLVIARMI
                     PGFRAMQERIDSVNRVLREQITGIRVVRAFVREEHERKRFAVANDHLADATLRVGKLMA
                     LMFPLVMVITNVTIVAVIWFGGHAVSDGTVEIGALTALMSYVMQILMSV"
     PFAM_domain     6915..7358
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_703_0184"
                     /evalue="4.10E-28"
                     /label="ctg1_703"
                     /locus_tag="ctg1_703"
                     /protein_end="498"
                     /protein_start="350"
                     /score="98.7"
                     /tool="antismash"
                     /translation="LSGISFEVTPGTTTAIVGSTGSGKTTLLGLVPRLIDATEGKVSVG
                     GTDVKRLDPDELRSVVGLVPQRPYLFSGTIRSNILHGKSDATDDEIWEALRIAQADEFV
                     SAMPDGLDTHVAQGGTTVSGGQRQRLAIARALVRRPAVYLFDDS"
     CDS             7595..9514
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     299; E-value: 4.1e-91)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 369.7; E-value:
                     4.4e-112)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_704"
                     /transl_table=11
                     /translation="MTRPGGPMAAGGPESKPRSFWPSIKRVVAQLGSYRGLMTVTLGSI
                     VGSVILLAVAPRVLGHATDLVFNGVIGRMLPAGQSKDQAVAGLRDRGDDTFADMVSSMD
                     VTPGVGVDFGDVGRVLLLTLVMYVVASGLAWLAAYLLNIIVVETIRDLRAKVEEKVHRL
                     PLRYYDTMPRGELLSRVTNDLDNLSQSMQQTIAQFVNSVLTVVALLVMMIWISPLLALI
                     AVATVPLAIIATAVIAKRSKPHFSAQWASTGALNAQVEEAFTGHELVTAFGRQREIEAT
                     FDERNEKLYQSSWRAQFISGVIMPTIMFLGNLNYVAVAVVGGLRVASGSLSLGEVQAFI
                     QYSRQFTQPLTQIGSMINLMQSGVASAERIFDILDAEEQTPDAANPKTPPVDRGLIEFD
                     DVSFRYVEDKPLIENLTLTARPGHMVAIVGPTGAGKTTLVNLIMRFYDVDSGTIRVDGV
                     DSAEMTRDDLRERTGMVLQDSWLFGGTIYDNIAYGDPSATREEVLEAARMSHVDHFVRT
                     LPDGYDTVLDDEGGGVSAGERQLITIARAFLARPTILILDEATSSVDTRTELLIQKAMA
                     NLRTDRTSFVIAHRLSTVRDADVIVVMENGHIVEQGNHDELLAARGAYCRLYQSQFTAA
                     IEAG"
     PFAM_domain     7745..8644
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_704_0185"
                     /evalue="1.20E-59"
                     /label="ctg1_704"
                     /locus_tag="ctg1_704"
                     /protein_end="350"
                     /protein_start="50"
                     /score="202.4"
                     /tool="antismash"
                     /translation="LLAVAPRVLGHATDLVFNGVIGRMLPAGQSKDQAVAGLRDRGDDT
                     FADMVSSMDVTPGVGVDFGDVGRVLLLTLVMYVVASGLAWLAAYLLNIIVVETIRDLRA
                     KVEEKVHRLPLRYYDTMPRGELLSRVTNDLDNLSQSMQQTIAQFVNSVLTVVALLVMMI
                     WISPLLALIAVATVPLAIIATAVIAKRSKPHFSAQWASTGALNAQVEEAFTGHELVTAF
                     GRQREIEATFDERNEKLYQSSWRAQFISGVIMPTIMFLGNLNYVAVAVVGGLRVASGSL
                     SLGEVQAFIQYSRQFTQPL"
     PFAM_domain     8831..9277
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_704_0186"
                     /evalue="6.50E-30"
                     /label="ctg1_704"
                     /locus_tag="ctg1_704"
                     /protein_end="561"
                     /protein_start="412"
                     /score="104.5"
                     /tool="antismash"
                     /translation="ENLTLTARPGHMVAIVGPTGAGKTTLVNLIMRFYDVDSGTIRVDG
                     VDSAEMTRDDLRERTGMVLQDSWLFGGTIYDNIAYGDPSATREEVLEAARMSHVDHFVR
                     TLPDGYDTVLDDEGGGVSAGERQLITIARAFLARPTILILDEATS"
     CDS             complement(9851..10546)
                     /locus_tag="ctg1_705"
                     /transl_table=11
                     /translation="VTGILEFASNNWWLIFPIGGVVGGWAGSVAKYNEKRRKDKIELAR
                     IKAAAQTEQLKLTTTSVEQLRKTLKQHDALNEKWFAYELDLATLIEYPLMTDMREPLTL
                     AFHRARVHADDLRPEPPRAGDTETTLAPVDFADYREAVGDYAAAFDAAEREARRRKQAG
                     FSPIEREALDRARKLINIASDSGATAAERQAAYKKARSELDGLLDVPPLAAERLERQIA
                     GALERGRGD"
ORIGIN
        1 gagaaggtac agcgtcggct tcggtccgcc gccgccggcc gagacgatgc acacgggcac
       61 ggtccggttc atggcgttcg agcggacgta ttcgacgttg caaccattgg ctgcggacgc
      121 cggcggagct gcgaccagcg tggcacctga cacggccacg agagccacga gtccggcgac
      181 gaggcgctta cgggcgcgag tcagcattcg tcagttttcc tttggatctc ggccggagtc
      241 ggccgcttct gggtcttccc taccgggtac tgcggaagtc gtacgtaggg ggattctatt
      301 gatccccgtc gggagcggta cccgtcgtcg agaagtgtaa cggcacgata acgtcgcggc
      361 aaaggctgga ctgaccttcg tgacgcatac gggtagtggc gcgtgtcaca tttgccccat
      421 tgtgaacagc ccatatgggc catacgcggc acaactgtcc gattctgccc tccgaacgga
      481 cgaaattgcc gcgaccgcac cgttattcgt ttgggtggtt aacggtgatg tgggaatcgg
      541 ttcgatctcc ggggcggtcg tatcggccaa ccaggccgca ccccgacccc gtactcacta
      601 gggtcggggc cgtggacatg ggtgaatacc tcggcgccga cgcgaccgcc ctcgccggac
      661 tcgtcgcatc gggtgaggtc acggctgccg aactcctcga cctggcccgg gcccgtgccg
      721 ccgcggtgaa cccggacctg aacgccatcg tcatcccgat cgaggccgag gccgaccacc
      781 gggcccgcac ggagttgacc gggccgttcg ccggcgtccc cttcctgatc aaggacctcg
      841 cccaggacta ccgcggctat ccgacgacgc gcggctctcg gtcgttggcg cggcacgtcg
      901 ccaccgagca cgcgacggtc gtccagcgat tcctcgatgc gggtctggtc gtcttcggga
      961 agaccaacac cccggagttc ggttcgaagg cgatcaccga atccgtcctg tggggtccgg
     1021 cgcgcaaccc ctggaacctc gacgtgaccc ccggcggctc gtccgggggc agcgccgcgg
     1081 ccgtggccgc gggcgtcgtg cccgcggccg gcgcgaacga cggcggcggt tcgatacgca
     1141 tcccggcggc gtgtaccgga ctcgtcggac tgaaggcgtc gcgcggcctg atgccgttcg
     1201 ggcccgccac cggcgagccg ctcttcggga tgggcgtcga gggtgtcgtg acccgcacgg
     1261 tgcgcgatgc ggccgccctc tacgacgcga tcatcggccc caccgcgtcg tcgacctatc
     1321 ccgcccccct ccacaccgag tcgttcacga cgcggatcgc ctctccaccg cggctgctgc
     1381 ggatcggtta caccacacgt tcggccatca accccgcacc gcaccccgaa gcggtggcgg
     1441 ccgtcgaaca cgccgcgaaa ctgctcaccg aactcggcca ccaggtcgac gaggtggacc
     1501 cgccgcacga cgatgcggag cttgcccgcg acttcctcga gatctggttc gccaaggcgg
     1561 ccgcccaggt cgacgaggcg cggcgcctgt ccggtgccgg cgacgccgac ttcgaggcgg
     1621 acactctcgc cctcgccgag atcggccggg cggccggggt ggtgccgctc ttccgcgcgc
     1681 tcgaccacgt caaccaccac gttcgtgctc tggaacgctt ccacgagacc cacgacctgc
     1741 tcctgacccc gaccctcgcc gtcccgccgc cggccgtcgg gtcgatgacg accccgccgc
     1801 tcctccagca ggcggcgcgg ctcgcggccc gcgcccgcat cggcaaggtg atgtcgcggg
     1861 tggggatcgt cgaccagctc gtcgaggaga atctcggctg ggtgccctac acccagctgg
     1921 cgaacatgac cggacgtccg gcgatcagcg tgcccctgca ctggaccggg accgggctcc
     1981 cgctcggcgt ccagttcgtc ggccgtctgg gcgccgacgg tgacctcctg gctctcgccg
     2041 catccctcga ggacgccgcg ccgtggttcc accggtacgc cgacatctcg atatgacgcg
     2101 gcgctaatgt tctctcggga tcgcatgtcc gggtgggggc acgcggcaga tcgacgcggt
     2161 gaggagttgt cgtgacgaag caggtggccg acgcggtggt cgtcggtgcg ggtctggcgg
     2221 gtctggtcgc gacatacgag ctcaccaagg cgggccgacg cgtggtggtg gtcgatcagg
     2281 agaaccgcaa aaatcttggc ggacaggcct tctggtcgct gggcgggctg ttcatggtgg
     2341 acacccccga acagcgcagg ctcggcatca ccgactccgc cgacctcgct ctgcaggact
     2401 ggatggggtc ggcgggcttc gaccgcgacg acgaggacta ctggccgcgt cagtgggccc
     2461 gggcctacgt cgacttcgcc gccactgaga agcggcagta tctgcacgat ctcgggctgc
     2521 gcatcacccc gatcgtcggc tgggccgaac gcggcggcgg cttcgccgac ggacacggca
     2581 actccgtgcc gcgcttccac ctcacctggg gcaccggacc cgaagtggtc cggatcttcg
     2641 ccgaaccggt cctcgaggcc gaaaaacgtg ggctggtcga gttccagttc cggcatcggg
     2701 tcgacgaact ggtcgtcgaa gacggtgccg ccgtgggcgt gcggggagcc accctcgcgc
     2761 cgaccgacct cgatcgcggc aaggcgtcga accgcgatgt ggtgggcgac ttcgagattc
     2821 gtgccggagc ggtgatcgtg acgtccggcg gcatcggcca caaccacgac ctcatccgca
     2881 agaactggcc ggtcgaccgt ctcggtcctg caccgaagac gatgatctct ggcgtcccgg
     2941 cgcatgtcga cggccgcatg ctggagatca gcgaggatgc cggcgcaaac atcgtcaacc
     3001 gcgaccgcat gtggcactac accgagggca tccacaactg ggacccgatc tggcccgacc
     3061 acgccatccg gatcatcccg ggaccgtcgt cgctgtggct cgacgcgaac ggcaaccgcc
     3121 tcgcaccgcc gaacttcccc ggcttcgaca cgaactcgac gatgaaggcg atcctcgccg
     3181 ccggccacga ctactcgtgg ttcatcctca cccagtccat cgtcgagaag gagttcatgc
     3241 tgtcgggttc cgaacagaac cccgacatca cctccaagga tctgaagctc gccgcgaaga
     3301 gccgactcgc caagggggcc cccggaccgg tggatgcctt cgtgcgcaac ggcatcgact
     3361 tcgtggtcgc cgacaacctg cccgaactgg tcagcgggat gaacgcgatc gcacgcggcc
     3421 ctgaactgga cctcgcgcac atcgaacgcg tcatctcggc ccgcgacgcc gaggtggaga
     3481 acaagttctc caaggacgcc cagctgatgg cgatcaacaa cgcgcgacag ttcatcggcg
     3541 acaggatcgt tcgagtggcc aagccccacc gcatcctcga ccccacgcac ggtccgctga
     3601 tcgcggtgcg gctcaacatc ctcacccgca agaccctcgg cggcctcgag accaacctcg
     3661 actcacaggt gctccgcccc gatggcagcg ccttcgacgg cctgttcgcg gccggcgagg
     3721 tcgcgggttt cggtggcggc ggtgtgcacg gttacaacgc cctcgagggc accttcctgg
     3781 gcgggtgcat cttctccggg cgtgcagccg gaagggccgt cgcgcgcagc tgatctcggc
     3841 gtccggacac gcccttcgag acggtccgaa aagggttgcc tgccctactt tttcacggca
     3901 cggtccgcga tcccatttcg gacatgcgtc ggctagggta ttgggcgtgc ccgtgccgca
     3961 gacgatcctg acgcgtaaga ccaagtcggc gatctttctc gtcctcacca tcaacgacgg
     4021 tggcgaggac acggttcgtg atgtgctcga ggagatcccg ggcctgaaca atgcggtgtc
     4081 ctcgcgcgcc ccggaggccg cgctggccgg catcgtctcg atcggttccg acgcctggga
     4141 ccggttgttc gacggccccc gcccgcgttc gctgcggccg ttcgtcccct acgagggcgc
     4201 ggtccacacc gcgccggcga cccccgcgga tctgctggtc cacatcaagt ccgaccagat
     4261 ggacctgtgc ttcgagctcg gccgcctcat caccgacgcc ctcggcgacg cggtgaccgt
     4321 cgtcgacgag gtgcacggct tccgctactt cgacctgcgt gatctcatcg gcttcgtcga
     4381 cggcaccgag aaccccgtcg gacaggccgc gatcgacgcc atcaccgtcg gtgacgagga
     4441 ccctgacttc gccggcggca gctacgtcgc catccagcgc tacgtccacg acctgtcgtc
     4501 gtggaacgac ctgagcacga gcgagcagga agccgcgatc ggacgcacca agctcgacaa
     4561 cgtcgagatg tccgacgacg tgaaaccgcc caactcccac atcgccctca acaaggtcga
     4621 agacgagaac ggcgaggaga tcgacgtcgt ccgcgacaac atgccctacg gcgatgtctc
     4681 cgggaacggc gagaacggca ccttctacat cgcctactcc gccggccccg acgtcaccga
     4741 ggagatgctg cgcaagatgt tcatcggtga ccccccggga acctacgacc gcctcctcga
     4801 cttcaccacc gccgtcaccg ggtcgcagtt cttcaccccg accctcgact tcctcgagga
     4861 cctgccgccc gcacccggcg ccgccgaacc cgccgcccag accccggtcc gccgcgctga
     4921 cggatccctg gggatcggtt ccctgcacta gcccgccaca gaccgaccac cgcccgacac
     4981 caccgcacca ggaggccccc atgaacaacc tgcaccgcga gctcgccccc atctccgagg
     5041 ccgcctgggc agagatcgag gaggaggcca cccggtcgtt caagcggaac atcgccggtc
     5101 gccgactcgt cgacgtgaag ggaccgatgg gtcaggacac cgcagccgtc accctgggcc
     5161 accgcagcaa gatcgactcc ccggccgacg gcatccaggc cttcatccgc cgaacccagt
     5221 cgctggtcga gctgaaggta ccgttcaccg tctcccgcga ggccatcgac gacgtcgacc
     5281 gcggtgctca ggactccgac tgggatccgg tcgtcgaagc cgcgcgccaa ctcgcgctcg
     5341 ccgaggaccg agcgatcttc gagggttacg ccgccgcatc gatcagcggt atccgcgccg
     5401 aggccacggc gaccccgatc cagctgcccg aggacgtccg cgactacccc gaagccgtca
     5461 gccaggcact caccactctg cggctcgcct ccgtcgacgg gccgtactcc gtcgccatgt
     5521 cggcggaggt gtacacacag gtgaacgaga cgtcgaacca cggctacccc atccgccagc
     5581 acatccagcg gctcctcgac ggggacatcg tctgggcgcc ggccatccgc ggcgcattcg
     5641 tcatgagcac ccgcggcggc gacttcgagc tgaccatcgg ccaggacgtg tcgatcggct
     5701 acgactccca cgacgccgac gtggtgaatc tgtacttcca ggaatcgttc acctacctca
     5761 cccacaccgg ggaggcagcc gtcgccctct tcggcggctg atcgacggga gaccgacgta
     5821 cgccttttag ccgaggcaac tagtctggcg caggtgatcg tgccatgctg acccgcctca
     5881 tcagtacgta cctgcagcgg taccgcatca acatcgtcct ggtggtgacg ctgcagttcg
     5941 tcgccaccgc ggcgatgctg tacctgccga gcctgaacgc cgacatcatc gacaacgggg
     6001 tggcgaccgg cgacaccggt tacatcatgc gcatcggcgg ctggatgctg ctggtgagca
     6061 tcgtgcagat cgtggcgacg atcatcgccc agttcttcgg gtctcgggcc gcgctcgggg
     6121 tgggccgcga catccgcagc gacctgctgc accgggtcaa ctcgttctcc gcccgcgagg
     6181 tcggtacgtt cggcgccccg tcgttgatca cgcgcaccac caacgacgtc cagcaggtgc
     6241 agatgctgat cgtcatgtgc agcgcgatcc tcgtaatggc gcccatcatg tgcatcggcg
     6301 ggatcgtgat gggcatccgg gaggcccccg cgttgtcgtg ggtcatcgcg atcgcggtac
     6361 cgatcctcgg gttggcgatg ggcctcgtca tcgcacgcat gatccccggt ttccgggcca
     6421 tgcaggaacg catcgactcg gtgaatcgtg ttctacgcga gcagatcacg ggaatccgcg
     6481 tggtgcgcgc ctttgtgcgg gaggagcacg agcgcaagcg tttcgccgtc gccaacgacc
     6541 acctcgccga cgccacgctg cgggtgggca agctgatggc gctgatgttc ccgctcgtca
     6601 tggtgatcac caacgtcacg atcgtcgcgg tcatctggtt cggcggtcac gccgtctccg
     6661 acggcacggt cgagatcggc gctctcaccg cgctgatgag ctacgtcatg cagatcctca
     6721 tgtcggtgat gatggcgtcg ttcctggcca tgatggcgcc gcgcgccgcg gtctgtgccg
     6781 agcgcatcac cgaggtcctc gacaccgaga cctcggtgca tccccccgtc gacccgatcg
     6841 gcttcgccgg ccatcccggc accgtgaagt tcgacgcagc cgagttccgc tatcccggcg
     6901 ccgacgaccc ggtgctgagt ggcatcagct tcgaggtcac accggggacc acgacggcca
     6961 tcgtcggatc gaccgggtcc ggcaagacga cactcctcgg actcgtaccc cggctcatcg
     7021 acgccaccga gggcaaggtc agcgtcggcg gcaccgacgt gaagcgactc gaccccgacg
     7081 aactgcgctc ggtggtcggc ctcgtcccgc agcgccccta cctcttctcc ggcaccatcc
     7141 ggtcgaacat cctgcacggc aagtccgacg ccaccgacga cgagatctgg gaggcgctgc
     7201 gcatcgccca ggccgacgag ttcgtctcgg ccatgcccga cggcctcgac acccacgtcg
     7261 cccagggcgg caccaccgtc tccgggggac agcgacagcg cctcgcgatc gcccgtgcac
     7321 tcgtccggcg ccccgccgtc tacctgttcg acgactcgtt ctcggcgctc gacctcacca
     7381 ccgacgccaa gctccgggcg gcgctgcgac cggccacccg cgacgcgtcg gtgatcgtgg
     7441 tcgcgcaacg catctcgacc atcgtcgacg ccgagcagat cgtcgtcctc gaccgcggcc
     7501 gaatcgtcgg catcggcaca cacgacgacc tgctggcctc gtgtcccacc tacgctgaga
     7561 tcgccgaatc ccagctggcc atggaggagc gcgcatgacc cgcccgggtg gaccgatggc
     7621 cgccggcggt cccgagtcca agccgcgctc gttctggccg tcgatcaaac gggttgtcgc
     7681 ccaactcggt tcataccgcg gcttgatgac cgtgacgctg ggttcgatcg tcggatcggt
     7741 catcctgctg gccgtcgcac cgcgcgtcct cggtcacgcc accgacctcg tcttcaacgg
     7801 cgtcatcggc cggatgctgc ccgccgggca gtcgaaggac caggcggtgg ccggcctgcg
     7861 cgaccgcggc gacgacacct tcgccgacat ggtctcgtcg atggacgtga cgcccggtgt
     7921 cggggtcgat ttcggcgacg tcggccgcgt cctgcttctg accctggtga tgtacgtcgt
     7981 ggcgtcggga ctggcctggc tggccgctta cctgctgaac atcattgtcg tggagacgat
     8041 ccgagaccta cgcgcgaagg tcgaagagaa ggtccaccgc ctgccgctgc ggtactacga
     8101 cacgatgccg cgcggtgagc tgctcagtcg ggtcaccaac gacctcgaca acctgtcaca
     8161 gagcatgcag cagaccatcg cccagttcgt gaactcggtg ctgacggtcg tcgcgctgct
     8221 ggtgatgatg atctggatct cgccgctcct cgcgctgatc gcggtggcga ccgtgccgct
     8281 ggcgatcatc gcgaccgccg tcatcgcgaa gcgttccaag ccccacttct ccgcacagtg
     8341 ggcgtcgacc ggtgccctca acgcccaggt cgaggaagcc ttcaccggac acgaactggt
     8401 gaccgccttc ggtcgtcagc gggagatcga ggcgaccttc gacgagcgca acgagaagct
     8461 gtaccagtcg agttggcggg cgcagttcat ctccggcgtc atcatgccga ccatcatgtt
     8521 cctcgggaac ctcaactacg tggccgtcgc cgtggtcggt ggcctgcggg tggcgtcggg
     8581 ttcgctgagc ctcggtgagg tgcaggcgtt catccagtac tcccgccagt tcacgcagcc
     8641 gctcacccag atcgggtcga tgatcaacct gatgcagagc ggcgtcgcgt ccgccgagcg
     8701 catcttcgac atcctcgacg ccgaggaaca gaccccggac gcggcgaacc cgaagacgcc
     8761 gccggtcgac cgcggtctca tcgagttcga cgatgtctcg ttccgctatg tcgaggacaa
     8821 gccgctcatc gagaacctca cgctgacagc gcgtcccggg cacatggtcg ccatcgtcgg
     8881 accgaccggc gccggcaaga ccacgctggt caatctgatc atgcggttct acgacgtcga
     8941 ctccggaacc atccgcgtcg acggcgtgga ctcggccgag atgacccgcg acgatctccg
     9001 tgagcgcacc ggcatggtgc tgcaggactc gtggctgttc ggcgggacga tctacgacaa
     9061 catcgcctac ggtgacccct ccgccacccg cgaagaggtc ctcgaggccg cccggatgag
     9121 tcacgtcgac cacttcgtcc gcactctccc cgacggttac gacacggtcc tcgacgacga
     9181 gggcggcggc gtcagtgccg gtgagcgaca gctcatcacg atcgcccggg cgttcctcgc
     9241 ccggcccacg atcctcatcc tcgacgaggc gaccagttcc gtcgacaccc gcaccgagct
     9301 gctcatccag aaagcgatgg ccaacctccg caccgatcgc acgagtttcg tgatcgcaca
     9361 ccgtctctcg acggtccgcg acgccgacgt gatcgtcgtg atggagaacg gtcacatcgt
     9421 cgaacagggc aaccacgacg aactcctcgc cgcgcgcggc gcgtactgcc ggctctacca
     9481 gagccagttc accgcggcga tcgaggcggg ctgagcccca cgctgcgatg cgctggcgcc
     9541 gactccctcg cttcttgggg tgcgaggagc gacagccccc ctgctccctg aggtgcgagg
     9601 agcgctagcg acgagcctcg aagggctggc gagttaccct gctacgcaac cacagtccgg
     9661 aatgaagtcg cgtgcgacat caacccgtcg gcacgacctc gatcgagctc gtacatccta
     9721 agcgatgtcg catgcgactt cacttcggcg gaccgtcgat gatcgccgtc cccgtgagtg
     9781 tcgctcgagg gcatatattg ccctcgaaga ctgctgacgg ggatggattt ccggctgagg
     9841 tgcgaggagc tcagtccccg cgaccccgtt cgagcgcacc ggcgatctgg cgttcgaggc
     9901 gttcggcggc aaggggcggg acgtcgagga ggccgtcgag ttcggaccgc gccttcttgt
     9961 aggcggcctg gcgttccgct gcggtggcac cggagtcgga ggcgatgttg atgagtttgc
    10021 gggcgcggtc gagcgcttcg cgttcgatcg gggagaaccc ggcctgcttg cggcgtcgtg
    10081 cctcgcgttc ggccgcgtcg aaggccgcgg catagtcacc gaccgcctcg cggtagtcgg
    10141 cgaagtcgac cggggcgaga gtcgtctcgg tatcgcctgc acgcgggggt tccgggcgca
    10201 ggtcgtcggc gtggacccgc gcgcgatgga aggcgagagt gagtggctct cgcatgtcgg
    10261 tcatgagggg gtactcgatg agcgtggcca ggtcgagctc gtaggcgaac cacttctcgt
    10321 tgagcgcatc gtgctgtttg agtgtcttgc ggagttgctc gacggacgtc gtggtcagtt
    10381 tcagctgttc ggtctgggcg gcggccttga tccgggccag ttcgatcttg tccttgcgcc
    10441 gcttctcgtt gtacttcgcg accgacccgg cccagccgcc gacgacgcca ccgatgggga
    10501 agatcaacca ccagttgttg ctcgcgaact cgaggatgcc cgtcacaggt caactgtacc
    10561 gagaccgacc gcccgcgatc agggtgaacg cacggccgat ccgggcgcgc atcagctcat
    10621 cgccgagacc ctcgacgagc ggcgagagtg gttgcgcgac aagaaacccc tacagatccg
    10681 ggatcggcag gtccaggttc ggtgcgatga ttccgccgtc gacctcgagg atcttgccgg
    10741 tgacgtaggc acccgccggt gaggccaggt acagggccgc ggcagcgatg tcctcggggt
    10801 c
//
