LOCUS       NC_020291.1            20778 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_020291.1 Clostridium saccharoperbutylacetonicum N1-4(HMT),
            complete sequence.
ACCESSION   NC_020291
VERSION     NC_020291.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:47:36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2478575
            Orig. end    :: 2499353
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20778
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2488575:2489353]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10778
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20778
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20778
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="8"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             345..704
                     /locus_tag="ctg1_2179"
                     /transl_table=11
                     /translation="MELLNHYKGFIIIGISGFIGFLGIVSLIKKPKALSRFEAFWTALV
                     LCSEGVYLGFCINSQEAVLEIIFLGVAIFLLWVIILFLFRRPKFEHRGIVMITCLVGII
                     LYLALFYLNHFNLLG"
     CDS             893..2875
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 189.5; E-value: 2.3e-57)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2180"
                     /transl_table=11
                     /translation="MHILSIFRKKIIEYLHLVVMCVSLYYVSKFNFVYLDASAEIVTVL
                     FGFILILIILSTIKACDSKYFHLIAFILSIFGIIALFVDDYGENNLLYILFQYYECILL
                     NLSVKYINKKANLSNLFSENKILVSLFLFITFVISYVSKNYDTKYSLDILGSVSAVLII
                     LGYIIFFYRIIKTKANILNGSKLNLFSLIFFKSLSYLCFSLFNDTTINILGHLFENIVY
                     YYIFNIIIKEIVINPYNNLFNRFMNKSQELEIANKKIDKISHKAANIEKLNDKFINLIP
                     DGIIIIRDKKIESVNDRLLNMFDINDELEVEKADFDKILDSSQLDIFMSRINSMDSRIL
                     EKPQEYEIKWDGMKKWVEVKSLIANDERGEYIISAIRNIEDRKKVEEAEKLLELKNKEE
                     SLKNDFFANISHELRTPINVIYSALQVQNGYLKKDNCNENVLKYNLIIKQNCLRLMRLI
                     NNIIDITRIESSFFIPNYKIENIVYLVEEITMSIAVYVKSKNIKLIFDTEVEEAYVNCD
                     SNLIERIMLNVLSNAVKYGKEGGNIFVNIYKDGENNILISVKDDGMGIPSDMQANIFER
                     FSKVDNSISRKIEGSGIGLSLVKQLVEIQQGTIVCESELNVGSEFKITFPTVEYSLEDV
                     TDEEQLNCYSNNAIETAEIEFSDIY"
     PFAM_domain     2096..2299
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2180_0301"
                     /evalue="3.30E-11"
                     /label="ctg1_2180"
                     /locus_tag="ctg1_2180"
                     /protein_end="469"
                     /protein_start="401"
                     /score="43.1"
                     /tool="antismash"
                     /translation="KNDFFANISHELRTPINVIYSALQVQNGYLKKDNCNENVLKYNLI
                     IKQNCLRLMRLINNIIDITRIES"
     PFAM_domain     2441..2770
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2180_0302"
                     /evalue="1.00E-23"
                     /label="ctg1_2180"
                     /locus_tag="ctg1_2180"
                     /protein_end="626"
                     /protein_start="516"
                     /score="84.1"
                     /tool="antismash"
                     /translation="DSNLIERIMLNVLSNAVKYGKEGGNIFVNIYKDGENNILISVKDD
                     GMGIPSDMQANIFERFSKVDNSISRKIEGSGIGLSLVKQLVEIQQGTIVCESELNVGSE
                     FKITFP"
     CDS             3051..3863
                     /locus_tag="ctg1_2181"
                     /transl_table=11
                     /translation="VKGKVLMATFKRNFIVMLRAYPMSFFVGNLLTGFYTVVGALFMYK
                     MLFNGAVGKEFLGYTGTGDYMSYVILGSLTYIYVVRTCLNVSRSLITELREGTLESLML
                     APFKRGEYFIGNMLQQTVATTFEVSISLIIAIPFGLNLSSVNISALIISALLGLYGFFG
                     LSMVLASIMLYTRDTYISQNTLFVGMLLLCGITFPTEYLPTVLRWMGELIPVTEISNLV
                     RGSVLLGKGIFEQTNTIIYVFLLSTVYMIIGFLSLKKIEFIALEKIQG"
     PFAM_domain     3066..3725
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2181_0303"
                     /evalue="2.50E-15"
                     /label="ctg1_2181"
                     /locus_tag="ctg1_2181"
                     /protein_end="225"
                     /protein_start="5"
                     /score="56.6"
                     /tool="antismash"
                     /translation="LMATFKRNFIVMLRAYPMSFFVGNLLTGFYTVVGALFMYKMLFNG
                     AVGKEFLGYTGTGDYMSYVILGSLTYIYVVRTCLNVSRSLITELREGTLESLMLAPFKR
                     GEYFIGNMLQQTVATTFEVSISLIIAIPFGLNLSSVNISALIISALLGLYGFFGLSMVL
                     ASIMLYTRDTYISQNTLFVGMLLLCGITFPTEYLPTVLRWMGELIPVTEISNLVRGS"
     CDS             3873..4847
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 176.2; E-value:
                     1.5e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2182"
                     /transl_table=11
                     /translation="MIEARNLKKIYETKISKGLFKSEKVKFEAVKDVSIKLKEGQIIGL
                     LGINGAGKTTTIKMLTTLLSPTSGEYFVDGIDAVKNPMVIKKKINMVAGGEKMIYFRLT
                     PQENLWYYGQLYGIPNKLLQERIDYLLKLVGLYENKDKKVEEFSKGMKQRLQIARGLIN
                     DPQYIFMDEPTLGLDAVTSKELRENVKVLTKERGKGILLTSHYMEEVEELADYIYVLDK
                     GEIIKQGTVKELSKDVFTKIEYKLILHNNIEGFDNYLFNILASKDSTVEVYNDEKTYKI
                     ISSRNLSLDISKACINKGAIIKEYYEIVPNLEDTIIKLSKKGA"
     PFAM_domain     3960..4394
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2182_0304"
                     /evalue="1.90E-25"
                     /label="ctg1_2182"
                     /locus_tag="ctg1_2182"
                     /protein_end="174"
                     /protein_start="29"
                     /score="90.0"
                     /tool="antismash"
                     /translation="VKDVSIKLKEGQIIGLLGINGAGKTTTIKMLTTLLSPTSGEYFVD
                     GIDAVKNPMVIKKKINMVAGGEKMIYFRLTPQENLWYYGQLYGIPNKLLQERIDYLLKL
                     VGLYENKDKKVEEFSKGMKQRLQIARGLINDPQYIFMDEPT"
     CDS             4851..5660
                     /gene_functions="transport (smcogs) SMCOG1065:ABC-2 type
                     transporter (Score: 55.4; E-value: 8.5e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_2183"
                     /transl_table=11
                     /translation="MKTFFKVCSAEMKKQHLNYFHSKLIYVSLFLWPILNFITTYYSFK
                     PFRINNSNISYLNEENVVIFIVLGYMAMSLFRSLVQSAWNFSFERISGTLELIYLSPAS
                     RQGVILGNALSSLFESVVFMVLFTIGVLIFKREVLNINYLALMIVFIITLAMAVVWGML
                     LNSIFLFSRDSGFLFTILEEPMEIFSGVKVPTSVFPMWAKVISLVFPLTYAIEAVRKVV
                     LNGSPLSEMNNFIVIGLGIIILLYIACIQIIKLVEIHSRKTGDFTYF"
     PFAM_domain     4881..5513
                     /aSDomain="ABC2_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01061.26"
                     /description="ABC-2 type transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2183_0305"
                     /evalue="6.50E-13"
                     /label="ctg1_2183"
                     /locus_tag="ctg1_2183"
                     /protein_end="221"
                     /protein_start="10"
                     /score="48.7"
                     /tool="antismash"
                     /translation="EMKKQHLNYFHSKLIYVSLFLWPILNFITTYYSFKPFRINNSNIS
                     YLNEENVVIFIVLGYMAMSLFRSLVQSAWNFSFERISGTLELIYLSPASRQGVILGNAL
                     SSLFESVVFMVLFTIGVLIFKREVLNINYLALMIVFIITLAMAVVWGMLLNSIFLFSRD
                     SGFLFTILEEPMEIFSGVKVPTSVFPMWAKVISLVFPLTYAIEAVRKV"
     CDS             5816..6418
                     /locus_tag="ctg1_2184"
                     /transl_table=11
                     /translation="MIKNVVFDIGNVLLNFEPKEYVRSKVIEEKVEEIYESIFKSEEWP
                     MLDRGTITEAAAKANIIKRKIENEEFINAVFQDWYAILSPIESSVDILKKLKENGYKLF
                     YLSNFHLAAFEYVTKNHDFFELFDGGIVSYKEKLLKPEKEIYDKILDTYKLEPSETIFI
                     DDTEENVTAARKHGIHGIVLKDPKDLQALLNEFQVKV"
     PFAM_domain     5831..6358
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2184_0306"
                     /evalue="2.00E-15"
                     /label="ctg1_2184"
                     /locus_tag="ctg1_2184"
                     /protein_end="181"
                     /protein_start="5"
                     /score="57.5"
                     /tool="antismash"
                     /translation="VFDIGNVLLNFEPKEYVRSKVIEEKVEEIYESIFKSEEWPMLDRG
                     TITEAAAKANIIKRKIENEEFINAVFQDWYAILSPIESSVDILKKLKENGYKLFYLSNF
                     HLAAFEYVTKNHDFFELFDGGIVSYKEKLLKPEKEIYDKILDTYKLEPSETIFIDDTEE
                     NVTAARKHGIHGI"
     aSDomain        5996..6346
                     /aSDomain="TIGR01549"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v1: HAD hydrolase, family IA,
                     variant 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2184_0049"
                     /evalue="3.90E-06"
                     /identifier="TIGR01549"
                     /label="ctg1_2184"
                     /locus_tag="ctg1_2184"
                     /protein_end="177"
                     /protein_start="60"
                     /score="25.3"
                     /tool="antismash"
                     /translation="IIKRKIENEEFINAVFQDWYAILSPIESSVDILKKLKENGYKLFY
                     LSNFHLAAFEYVTKNHDFFELFDGGIVSYKEKLLKPEKEIYDKILDTYKLEPSETIFID
                     DTEENVTAARKHG"
     aSDomain        6188..6361
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2184_0048"
                     /evalue="4.60E-12"
                     /identifier="TIGR01509"
                     /label="ctg1_2184"
                     /locus_tag="ctg1_2184"
                     /protein_end="182"
                     /protein_start="124"
                     /score="44.3"
                     /tool="antismash"
                     /translation="ELFDGGIVSYKEKLLKPEKEIYDKILDTYKLEPSETIFIDDTEEN
                     VTAARKHGIHGIV"
     CDS             6446..7396
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 58; E-value: 1.2e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2185"
                     /transl_table=11
                     /translation="MKIAVIYEKGIKGEFVYSPLNEMFCAMHILIKPEHHLHRNKWIQK
                     IANNEKMLEAIKKYSDITEEYCIVMDFCAYFEECTELNILSAIEFLSQVPLNKINKIFK
                     AYDKRMNQSQYKEFLELLKRFYIEIFAEELKYIEPMITRILKKKAKLAEDIGIFNFVET
                     IHERIKVEEEKIKFYKNKEYVVKKAEIKTITINLSTFISPHLMLGIINNNLYLTYLVEL
                     DTYEKESPKDLERALKALGDGTRLRILKEISRKGKSTQELSTLLNISEAAVSKALKLLQ
                     EGELVKKERQGNYIIYTVNTISIDFIAYKIYEYIY"
     PFAM_domain     7148..7321
                     /aSDomain="HTH_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12840.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2185_0307"
                     /evalue="9.90E-10"
                     /label="ctg1_2185"
                     /locus_tag="ctg1_2185"
                     /protein_end="292"
                     /protein_start="234"
                     /score="38.4"
                     /tool="antismash"
                     /translation="RALKALGDGTRLRILKEISRKGKSTQELSTLLNISEAAVSKALKL
                     LQEGELVKKERQG"
     CDS             7707..8453
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     75.4; E-value: 7.2e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2186"
                     /transl_table=11
                     /translation="MKIANGVEMLELAAKNMKGEPTSIYPILICDKETIILVDAGYPGQ
                     LEQIRKEVEKTGVKFETVNMVLITHHDIDHIGSLASIVKELPEVKVLCHEEEKAYIEGV
                     KKPHKLAMLEANLDNLSQEMKGFYEHFKVGFEKARTKVDRTLKDGEELPYCGGITIIYT
                     PGHTMGHSCLYFKESKTLIAGDLLMVKEGVLVKAPESINFNDELCLKSLKKLMQYDIEN
                     VVCYHGGIYSNKVNERINELIETLAQ"
     PFAM_domain     7776..8387
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2186_0308"
                     /evalue="6.30E-22"
                     /label="ctg1_2186"
                     /locus_tag="ctg1_2186"
                     /protein_end="227"
                     /protein_start="23"
                     /score="78.6"
                     /tool="antismash"
                     /translation="IYPILICDKETIILVDAGYPGQLEQIRKEVEKTGVKFETVNMVLI
                     THHDIDHIGSLASIVKELPEVKVLCHEEEKAYIEGVKKPHKLAMLEANLDNLSQEMKGF
                     YEHFKVGFEKARTKVDRTLKDGEELPYCGGITIIYTPGHTMGHSCLYFKESKTLIAGDL
                     LMVKEGVLVKAPESINFNDELCLKSLKKLMQYDIENVVCYH"
     CDS             9000..9545
                     /locus_tag="ctg1_2187"
                     /transl_table=11
                     /translation="MAETILLALLFAKIRRYEIKPLFKTWTFYPIIIFEIIFLFGQLSI
                     FLGHYEFISFLKSLNTFYFCTYLLLVFKYRIYLQSIIGSIFMLIGGGLNDIVIKANDGF
                     MPVFPTLSYLTGYAKTEAFVIVKDIHMLGNSQTKLKILTDFIDLGYSILSIGDVFIRAF
                     VFIIIYNSIKKINNQRRK"
     PFAM_domain     9060..9506
                     /aSDomain="DUF5317"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17248.4"
                     /description="Family of unknown function (DUF5317)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2187_0309"
                     /evalue="2.90E-22"
                     /label="ctg1_2187"
                     /locus_tag="ctg1_2187"
                     /protein_end="169"
                     /protein_start="20"
                     /score="79.3"
                     /tool="antismash"
                     /translation="PLFKTWTFYPIIIFEIIFLFGQLSIFLGHYEFISFLKSLNTFYFC
                     TYLLLVFKYRIYLQSIIGSIFMLIGGGLNDIVIKANDGFMPVFPTLSYLTGYAKTEAFV
                     IVKDIHMLGNSQTKLKILTDFIDLGYSILSIGDVFIRAFVFIIIY"
     CDS             9546..9998
                     /locus_tag="ctg1_2188"
                     /transl_table=11
                     /translation="MLRLTVFEFIFRGMPEAFVVMFAMLMLSNARIDRNRYIISSLLLG
                     FGEYGIRFLPISFGVHTILGIFIMIIIMWSIDNVDVIFAIRSSLILTITMFIIEGLNII
                     ALKLIFKDVFDTIMLDTKLRTLTGIPSLIILVIISYIIYYLKKRKN"
     CDS             10001..10621
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2189"
                     /sec_met_domain="AgrB (E-value: 4e-42, bitscore: 142.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKIERICEKISGYISQELNFDDDKRAVINYGIFGLFQTGMCIIL
                     VILFGIFFNVTIEALIVSFTISILRKSSGGVHAKSPMRCAVIGTASSIGMALLSKNINM
                     SLVMVILVGSVIFIWSYYIINKIAPVDSIAKPIKNIEKRKRLKGTSIKTLSFYLITIIT
                     IILSYLYLENRNLLGYILCVYMGLLWQVFSLTKCGHIVLGKLG"
     PFAM_domain     10022..10582
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2189_0310"
                     /evalue="1.30E-41"
                     /label="ctg1_2189"
                     /locus_tag="ctg1_2189"
                     /protein_end="194"
                     /protein_start="7"
                     /score="142.1"
                     /tool="antismash"
                     /translation="CEKISGYISQELNFDDDKRAVINYGIFGLFQTGMCIILVILFGIF
                     FNVTIEALIVSFTISILRKSSGGVHAKSPMRCAVIGTASSIGMALLSKNINMSLVMVIL
                     VGSVIFIWSYYIINKIAPVDSIAKPIKNIEKRKRLKGTSIKTLSFYLITIITIILSYLY
                     LENRNLLGYILCVYMGLLWQVFSL"
     CDS             10653..10778
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2190"
                     /sec_met_domain="TIGR04223 (E-value: 5.6e-13, bitscore:
                     47.0, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKILMGIATIATVFASIVATSACWYVHYQPEEPKCLRDE"
     aSDomain        10662..10769
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2190_0050"
                     /evalue="4.40E-13"
                     /identifier="TIGR04223"
                     /label="ctg1_2190"
                     /locus_tag="ctg1_2190"
                     /protein_end="39"
                     /protein_start="3"
                     /score="47.0"
                     /tool="antismash"
                     /translation="KILMGIATIATVFASIVATSACWYVHYQPEEPKCLR"
     CDS             10835..12550
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 176.6; E-value:
                     1.9e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2191"
                     /transl_table=11
                     /translation="MKKIINNKQKQINDIVSVVKLSTLLLIGIILSKTFVKNNSAIWES
                     STFYILIILFIPLMLFVLVYLAWSFSVENKIKNKYRNIFNIIEINFFLIVFSAIIWVCG
                     VNGSQYKILYLFIIITTTIQYGMKRGLIVSIISSLIILGMDIMVVPNAYLNDFFQDDLI
                     LVGIFILTAWPLGFYVKIEGEHIKRLEEQINIDGLTELYNHRYFCDTLIEKVKAGERNN
                     KPVSMIFIDIDYFKQYNDTYGHQKGDYVLRKVAEIIKGNIREGDLSARYGGEEFAVILP
                     DTNEKEALNLAEHLRERIENTYFEGEDSQPNGKITASMGVSVYPDKAKDDIELIKSADD
                     ALYRAKFINKNKVESYTSILDEIKSNIDEKDVELVTSIKTLISVINAKDKYTYGHVERV
                     VIYSRLIAEKLQLSKRNKEILIYGAYMHDIGKINTRKEVLVKKMKLTDEEWEELKQHPA
                     NGAEIIKSVESLKEITPLIISHHERYDGKGYPNRLKGDEIPFLARILTVVDSFDAMTSN
                     RPYNTRKSYEDGIQELERCSGTQFDPEIVKAFVEVVRNDIEVSDLNGMNRKYAN"
     aSDomain        11399..11896
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2191_0051"
                     /evalue="3.80E-55"
                     /identifier="TIGR00254"
                     /label="ctg1_2191"
                     /locus_tag="ctg1_2191"
                     /protein_end="354"
                     /protein_start="188"
                     /score="184.1"
                     /tool="antismash"
                     /translation="LEEQINIDGLTELYNHRYFCDTLIEKVKAGERNNKPVSMIFIDID
                     YFKQYNDTYGHQKGDYVLRKVAEIIKGNIREGDLSARYGGEEFAVILPDTNEKEALNLA
                     EHLRERIENTYFEGEDSQPNGKITASMGVSVYPDKAKDDIELIKSADDALYRAKFINKN
                     KVE"
     PFAM_domain     11414..11887
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2191_0311"
                     /evalue="9.10E-47"
                     /label="ctg1_2191"
                     /locus_tag="ctg1_2191"
                     /protein_end="351"
                     /protein_start="193"
                     /score="158.9"
                     /tool="antismash"
                     /translation="NIDGLTELYNHRYFCDTLIEKVKAGERNNKPVSMIFIDIDYFKQY
                     NDTYGHQKGDYVLRKVAEIIKGNIREGDLSARYGGEEFAVILPDTNEKEALNLAEHLRE
                     RIENTYFEGEDSQPNGKITASMGVSVYPDKAKDDIELIKSADDALYRAKFINKN"
     aSDomain        12008..12280
                     /aSDomain="TIGR00277"
                     /aSTool="tigrfam"
                     /description="HDIG: HDIG domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2191_0052"
                     /evalue="6.50E-08"
                     /identifier="TIGR00277"
                     /label="ctg1_2191"
                     /locus_tag="ctg1_2191"
                     /protein_end="482"
                     /protein_start="391"
                     /score="30.3"
                     /tool="antismash"
                     /translation="TYGHVERVVIYSRLIAEKLQLSKRNKEILIYGAYMHDIGKINTRK
                     EVLVKKMKLTDEEWEELKQHPANGAEIIKSVESLKEITPLIISHHE"
     PFAM_domain     12164..12349
                     /aSDomain="HD_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13487.8"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2191_0312"
                     /evalue="8.80E-20"
                     /label="ctg1_2191"
                     /locus_tag="ctg1_2191"
                     /protein_end="505"
                     /protein_start="443"
                     /score="70.8"
                     /tool="antismash"
                     /translation="KLTDEEWEELKQHPANGAEIIKSVESLKEITPLIISHHERYDGKG
                     YPNRLKGDEIPFLARIL"
     CDS             complement(12657..14045)
                     /locus_tag="ctg1_2192"
                     /transl_table=11
                     /translation="MRKKDILELKRRLKKDDCTFTRMCGCYVDGQKNIVLKLKETFLNL
                     RDEEFYKYLEIAKKTLSGTIGNNLLELNFPLEEEGMGSHQLSLMELKKSRLKDDAKLDD
                     FYNKIIDSYDYTGNFLILLFHDAYDVMTRTTDNSKLDESEEVYEYILCAICPVELAKPA
                     LGYLEDEHKIGARIRDWIVGVPDLGFVFPAFIDRSTDIHSIIYYAKNAKDSHPEVMEEV
                     LGCSSKETATEQKEKFQTIISKAVGCDEEKSEHLFMEIQETLSSMAEEHIAVNGKNAEP
                     ILLSNDNIQDLLMESGISEEITAKIEKSYIDVFGDTPPIVDHLIDKKALTANEQRKKEE
                     RLEKKVKFLEERLEETKQSSQLVSEKEESIEKESSLESAADTILEAKTDIKLDDDSDRT
                     FEQNSNHELAVEEESNSDYDIILQVKPQKVAQIKSQIIDGKKCIVIPIDENEQANVNGV
                     DTLL"
     PFAM_domain     complement(12672..14045)
                     /aSDomain="DUF4317"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14199.8"
                     /description="Domain of unknown function (DUF4317)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2192_0313"
                     /evalue="1.30E-156"
                     /label="ctg1_2192"
                     /locus_tag="ctg1_2192"
                     /protein_end="458"
                     /protein_start="0"
                     /score="521.5"
                     /tool="antismash"
                     /translation="MRKKDILELKRRLKKDDCTFTRMCGCYVDGQKNIVLKLKETFLNL
                     RDEEFYKYLEIAKKTLSGTIGNNLLELNFPLEEEGMGSHQLSLMELKKSRLKDDAKLDD
                     FYNKIIDSYDYTGNFLILLFHDAYDVMTRTTDNSKLDESEEVYEYILCAICPVELAKPA
                     LGYLEDEHKIGARIRDWIVGVPDLGFVFPAFIDRSTDIHSIIYYAKNAKDSHPEVMEEV
                     LGCSSKETATEQKEKFQTIISKAVGCDEEKSEHLFMEIQETLSSMAEEHIAVNGKNAEP
                     ILLSNDNIQDLLMESGISEEITAKIEKSYIDVFGDTPPIVDHLIDKKALTANEQRKKEE
                     RLEKKVKFLEERLEETKQSSQLVSEKEESIEKESSLESAADTILEAKTDIKLDDDSDRT
                     FEQNSNHELAVEEESNSDYDIILQVKPQKVAQIKSQIIDGKKCIVIPIDENEQANVNGV
                     "
     CDS             14426..16489
                     /gene_functions="other (smcogs) SMCOG1061:methyl-accepting
                     chemotaxis protein (Score: 216.7; E-value: 1e-65)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2193"
                     /transl_table=11
                     /translation="MKKSIGGIKGRILIATVLVVLITVVSISGISIYQVNKKNYSDYLT
                     NSKGQMNTVSQAIKIFYDQIDKNLDMLATNPLVMSADNTITSYKGTTEETQMKPSANGE
                     LEKAIYKVFEQYGNSHEGTNYVYLGTKDGRYIQWPETTTFAGYDPVIRPWYVQAKDKNG
                     KIIRTEPYTFKSEMLTSNARSFTDKDGNFIGAIGLDVKQSKISEMLNQMKIGETGFSMI
                     IHTTGAIMADGKNPDNNFKKVQEIGIAGLDRLLTDQTNAFEVVINGEKYLVNPYKVEGT
                     DWILASLITQKELTGNAREIMKVVIISALIILVLVSILINFISSSITKPIVAVTGRVKE
                     FANLDFSSTNQLSSAYINRKDETGEMIRALKIMRENVADFIRKAADTTEHIAASSEELT
                     ATSEQAATASEEVAKTIEEIAKGASDQAKDTEITANNIGELGTLLEKELNYTKELNVAA
                     VRIEKQKEDGFLILKELINKTQKNSDASSNVYNIIMSNNDSAEKINSASTMIQSIAEQT
                     NLLALNAAIEAARAGEAGKGFAVVADEIRKLAEQSNNFTNDIKTIINELKTKSQNAVDL
                     MQETKYVVEEQATSVKETEGKFKGIAEAIDIIKNIIEKLNQSTSLMVENKDKIIDLTQN
                     LSAISEENAAATEETAASMEEQSATIQEIASAGERLATIAEELKVSIDKFKF"
     PFAM_domain     14561..15286
                     /aSDomain="dCache_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02743.20"
                     /description="Cache domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2193_0314"
                     /evalue="5.00E-21"
                     /label="ctg1_2193"
                     /locus_tag="ctg1_2193"
                     /protein_end="287"
                     /protein_start="45"
                     /score="75.4"
                     /tool="antismash"
                     /translation="NSKGQMNTVSQAIKIFYDQIDKNLDMLATNPLVMSADNTITSYKG
                     TTEETQMKPSANGELEKAIYKVFEQYGNSHEGTNYVYLGTKDGRYIQWPETTTFAGYDP
                     VIRPWYVQAKDKNGKIIRTEPYTFKSEMLTSNARSFTDKDGNFIGAIGLDVKQSKISEM
                     LNQMKIGETGFSMIIHTTGAIMADGKNPDNNFKKVQEIGIAGLDRLLTDQTNAFEVVIN
                     GEKYLVNPYKVEGTDWILAS"
     PFAM_domain     15869..16315
                     /aSDomain="MCPsignal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00015.23"
                     /description="Methyl-accepting chemotaxis protein (MCP)
                     signalling domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2193_0315"
                     /evalue="2.50E-36"
                     /label="ctg1_2193"
                     /locus_tag="ctg1_2193"
                     /protein_end="630"
                     /protein_start="481"
                     /score="125.2"
                     /tool="antismash"
                     /translation="NSDASSNVYNIIMSNNDSAEKINSASTMIQSIAEQTNLLALNAAI
                     EAARAGEAGKGFAVVADEIRKLAEQSNNFTNDIKTIINELKTKSQNAVDLMQETKYVVE
                     EQATSVKETEGKFKGIAEAIDIIKNIIEKLNQSTSLMVENKDKII"
     CDS             16909..17562
                     /locus_tag="ctg1_2194"
                     /transl_table=11
                     /translation="VDKVKSIDEVMEYIKDGMTIMVGGFMGVGTPEMLIDAIVKKNVKD
                     LTIIANDTGLPDKGVGKLVVNKQVKKVVASHIGLNPETGKQMNTGEMEVDLVPQGTLAE
                     RIRCGGAGIGGFLTETGIGTAVEEGKQKLKLNHKEYILELPLRADMALVGGSVVDKKGN
                     IFYNASTRNFNPLIATAADLVIVGAEKIVEVGDLDPNHVMTPGIFVDYIVGGDN"
     aSDomain        16918..17547
                     /aSDomain="TIGR02429"
                     /aSTool="tigrfam"
                     /description="pcaI_scoA_fam: 3-oxoacid CoA-transferase, A
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2194_0053"
                     /evalue="1.10E-68"
                     /identifier="TIGR02429"
                     /label="ctg1_2194"
                     /locus_tag="ctg1_2194"
                     /protein_end="213"
                     /protein_start="3"
                     /score="228.9"
                     /tool="antismash"
                     /translation="VKSIDEVMEYIKDGMTIMVGGFMGVGTPEMLIDAIVKKNVKDLTI
                     IANDTGLPDKGVGKLVVNKQVKKVVASHIGLNPETGKQMNTGEMEVDLVPQGTLAERIR
                     CGGAGIGGFLTETGIGTAVEEGKQKLKLNHKEYILELPLRADMALVGGSVVDKKGNIFY
                     NASTRNFNPLIATAADLVIVGAEKIVEVGDLDPNHVMTPGIFVDYIV"
     PFAM_domain     16921..17547
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2194_0316"
                     /evalue="3.80E-66"
                     /label="ctg1_2194"
                     /locus_tag="ctg1_2194"
                     /protein_end="213"
                     /protein_start="4"
                     /score="222.7"
                     /tool="antismash"
                     /translation="KSIDEVMEYIKDGMTIMVGGFMGVGTPEMLIDAIVKKNVKDLTII
                     ANDTGLPDKGVGKLVVNKQVKKVVASHIGLNPETGKQMNTGEMEVDLVPQGTLAERIRC
                     GGAGIGGFLTETGIGTAVEEGKQKLKLNHKEYILELPLRADMALVGGSVVDKKGNIFYN
                     ASTRNFNPLIATAADLVIVGAEKIVEVGDLDPNHVMTPGIFVDYIV"
     CDS             17562..18221
                     /locus_tag="ctg1_2195"
                     /transl_table=11
                     /translation="MDSKNAKEFIARRIAKELKDGDVVNLGIGLPTMVANYLPHGIDVT
                     FQSENGFVGLGNAPEEGKEDKDIVNAGAQYVTINNGAAFFDSATSFGIIRGGHVDVTVL
                     GALEVDEKGNLANYMIPGKMVPGMGGAMDLVSGAKKVIIAMLHTAKGESKILKECRLPL
                     TAVGKVSLIVTDMAVMEVTKEGLLLKEIAEGLTVEEVLNATEAELIIPDDLRVIAV"
     aSDomain        17577..18191
                     /aSDomain="TIGR02428"
                     /aSTool="tigrfam"
                     /description="pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2195_0054"
                     /evalue="1.10E-95"
                     /identifier="TIGR02428"
                     /label="ctg1_2195"
                     /locus_tag="ctg1_2195"
                     /protein_end="210"
                     /protein_start="5"
                     /score="316.9"
                     /tool="antismash"
                     /translation="AKEFIARRIAKELKDGDVVNLGIGLPTMVANYLPHGIDVTFQSEN
                     GFVGLGNAPEEGKEDKDIVNAGAQYVTINNGAAFFDSATSFGIIRGGHVDVTVLGALEV
                     DEKGNLANYMIPGKMVPGMGGAMDLVSGAKKVIIAMLHTAKGESKILKECRLPLTAVGK
                     VSLIVTDMAVMEVTKEGLLLKEIAEGLTVEEVLNATEAELII"
     PFAM_domain     17589..18167
                     /aSDomain="CoA_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01144.25"
                     /description="Coenzyme A transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2195_0317"
                     /evalue="3.70E-41"
                     /label="ctg1_2195"
                     /locus_tag="ctg1_2195"
                     /protein_end="202"
                     /protein_start="9"
                     /score="141.0"
                     /tool="antismash"
                     /translation="IARRIAKELKDGDVVNLGIGLPTMVANYLPHGIDVTFQSENGFVG
                     LGNAPEEGKEDKDIVNAGAQYVTINNGAAFFDSATSFGIIRGGHVDVTVLGALEVDEKG
                     NLANYMIPGKMVPGMGGAMDLVSGAKKVIIAMLHTAKGESKILKECRLPLTAVGKVSLI
                     VTDMAVMEVTKEGLLLKEIAEGLTVEEVLN"
     CDS             18386..18727
                     /locus_tag="ctg1_2196"
                     /transl_table=11
                     /translation="MKKVELKNVAPYNAPKHFDMKAMKLHGEAETGAKQFWMGMSYFLP
                     GGGAEYAYEDSPTEKIYFVLDGEITVKSKDETFVLKKDDSIFIGPNEGREMINETNKVA
                     TVLVVVSNN"
     PFAM_domain     18512..18712
                     /aSDomain="Cupin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07883.13"
                     /description="Cupin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2196_0318"
                     /evalue="1.60E-10"
                     /label="ctg1_2196"
                     /locus_tag="ctg1_2196"
                     /protein_end="109"
                     /protein_start="42"
                     /score="40.6"
                     /tool="antismash"
                     /translation="FLPGGGAEYAYEDSPTEKIYFVLDGEITVKSKDETFVLKKDDSIF
                     IGPNEGREMINETNKVATVLVV"
     CDS             18769..19554
                     /NRPS_PKS="Domain: PKS_KR (15-177). E-value: 1.6e-16.
                     Score: 52.5. Matches aSDomain:
                     nrpspksdomains_ctg1_2197_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     162.6; E-value: 1.9e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2197"
                     /transl_table=11
                     /translation="MDSKFINNLFDVKGKVAVITGATGALGKAVSFGYGLAGMKVFVTG
                     RSDKKCQELCSELEAQGIECGYSTGDPAVEADVKKVVNDAVGKFGEINVLVTAAGYNNP
                     QPIVEQALEEWKKIMDSDVQGTWLFCKYVGEKMIAQGKGGKVILVSSARSKMGMANYTG
                     YCTAKGGIDLMAQSLACEWTAKYKINVNTINPTVFRSDLTEWMFDPESAVYQNFLKRLP
                     VGRLGEPEDFVGPCIFLASSASDFMTGANVATEGGYWAN"
     aSDomain        18814..19299
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2197_PKS_KR.1"
                     /evalue="1.60E-16"
                     /label="ctg1_2197_PKS_KR.1"
                     /locus_tag="ctg1_2197"
                     /protein_end="177"
                     /protein_start="15"
                     /score="52.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVITGATGALGKAVSFGYGLAGMKVFVTGRSDKKCQELCSELEA
                     QGIECGYSTGDPAVEADVKKVVNDAVGKFGEINVLVTAAGYNNPQPIVEQALEEWKKIM
                     DSDVQGTWLFCKYVGEKMIAQGKGGKVILVSSARSKMGMANYTGYCTAKGGIDLMAQS"
     PFAM_domain     18829..19542
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2197_0319"
                     /evalue="8.00E-44"
                     /label="ctg1_2197"
                     /locus_tag="ctg1_2197"
                     /protein_end="258"
                     /protein_start="20"
                     /score="150.0"
                     /tool="antismash"
                     /translation="GATGALGKAVSFGYGLAGMKVFVTGRSDKKCQELCSELEAQGIEC
                     GYSTGDPAVEADVKKVVNDAVGKFGEINVLVTAAGYNNPQPIVEQALEEWKKIMDSDVQ
                     GTWLFCKYVGEKMIAQGKGGKVILVSSARSKMGMANYTGYCTAKGGIDLMAQSLACEWT
                     AKYKINVNTINPTVFRSDLTEWMFDPESAVYQNFLKRLPVGRLGEPEDFVGPCIFLASS
                     ASDFMTGANVATEGGY"
     CDS             19731..20666
                     /locus_tag="ctg1_2198"
                     /transl_table=11
                     /translation="MGKKIYVDLTHPFSADIPRWPYFVKPVIDSMHTLAKGGVLTQRID
                     CVQHTGTHCDAPRHVMEYEFDGRRARYTHEMPVDAYMGDAVCLEINIEPWGLILPEHLE
                     DACKRANIKPEELEGMVICLNTGMHRKFDDSKEYYHYSCGTGVEAGKWFVKHKVKCVAM
                     DMQALDHPLHTAMGNNGGTRMNLIGNSGRSITEEYKEKFGEEAYAEFDKDEYIRIHGKE
                     AYDAKFGDLEAIGCWGTWEPCHKQMLGHGIVGVENLGGNLDKVSGKRFRFLCMPIRWYM
                     GDGSMVRCVAEIDEDDVNDVPDRTYTYGGF"
     PFAM_domain     19749..20240
                     /aSDomain="Cyclase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04199.15"
                     /description="Putative cyclase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2198_0320"
                     /evalue="2.90E-28"
                     /label="ctg1_2198"
                     /locus_tag="ctg1_2198"
                     /protein_end="170"
                     /protein_start="6"
                     /score="98.9"
                     /tool="antismash"
                     /translation="VDLTHPFSADIPRWPYFVKPVIDSMHTLAKGGVLTQRIDCVQHTG
                     THCDAPRHVMEYEFDGRRARYTHEMPVDAYMGDAVCLEINIEPWGLILPEHLEDACKRA
                     NIKPEELEGMVICLNTGMHRKFDDSKEYYHYSCGTGVEAGKWFVKHKVKCVAMDMQALD
                     H"
ORIGIN
        1 aaaaggccaa ttaagtaggt tttgtgtgtc aaaaagaata aaaaataaat cttattcgcc
       61 tgccagattt ttctcacatg cgttcgaaaa ggcaaatgcg taaaaaaaat ctccggctcc
      121 acagtcgcct gcgatttttt tactaaaata attatttcaa tataaaattg agataaaatt
      181 attccaacag ctatacacta aaaatttgta atatgttata attttagaaa aagcattttt
      241 agggagagaa attgataact aatgttgaaa attgttgttt tacaaggaat aacgacttaa
      301 gggtatcagt ttattatttt aggtatataa aggggagaaa atgtatggaa ttattgaatc
      361 attataaggg gtttattatt attggaattt cagggtttat tggattttta gggatagtat
      421 ctctaattaa aaagccaaag gcactaagta gatttgaggc tttttggaca gccttagtac
      481 tatgttcaga aggagtttac ttgggatttt gcattaatag tcaagaggct gtacttgaaa
      541 ttatattttt aggggttgct atatttctat tatgggtaat aatattattt ctatttagaa
      601 gacctaaatt cgagcataga ggaatagtaa tgataacctg cttagtagga attatacttt
      661 atctagcttt gttttatttg aatcatttta atttattagg ataaataatt tatagataca
      721 tatttaaggc ttatgttatt tgtttagtaa cataagcttt tttgttgcta attgagaaaa
      781 aagtcataat ttgaatttta aatgtgaaat ttgattataa aagtagaaga aattaagaaa
      841 aaatatgtag aaaatgatag aatatgatag aatatatgaa aggaggcgaa ttatgcatat
      901 tttatcaatc tttcgaaaaa agataattga gtatttacat ttagtagtta tgtgcgttag
      961 cttatattat gtatcaaaat ttaattttgt atatttggat gcatctgcag aaatagtaac
     1021 tgttcttttt ggatttatac tcatattaat aatattaagt acaataaaag catgtgatag
     1081 taagtatttt catttgatag catttatact tagtattttt ggaattattg cattatttgt
     1141 tgatgattat ggagaaaata atttattgta tattttattt caatattacg aatgtatttt
     1201 attgaattta tcggttaagt atataaataa aaaggctaat ttgagtaacc tattttctga
     1261 aaataaaatt cttgtaagct tatttttatt tattactttt gttatcagtt atgtatcaaa
     1321 aaactatgat actaaatact ctttagatat acttggaagt gtaagtgcag tattaattat
     1381 actcggatat ataattttct tttatagaat tattaaaact aaagctaata ttctaaatgg
     1441 aagtaaattg aatttgtttt cattgatatt tttcaagagt ttatcatatc tttgtttttc
     1501 attatttaat gatacaacta ttaatatact ggggcacttg tttgaaaata tagtgtacta
     1561 ttacatattt aatataatta tcaaagagat agttataaat ccttataata atttatttaa
     1621 taggtttatg aacaaatcac aggagttaga aattgctaat aaaaagatag ataaaataag
     1681 tcataaggct gctaatatag aaaaattaaa cgataaattc attaatttaa ttccagatgg
     1741 aattataata atcagagata agaaaatcga atctgtgaat gatagacttt taaatatgtt
     1801 tgatattaat gacgaattag aagttgaaaa ggctgatttt gataaaatac tagatagttc
     1861 acaattagat atttttatgt caagaataaa tagcatggat agcaggattt tagaaaaacc
     1921 gcaagagtac gagataaaat gggacggaat gaaaaaatgg gtcgaagtaa agtcattaat
     1981 tgccaatgat gaaagaggag aatatatcat ttctgcaata cgaaatattg aagatagaaa
     2041 aaaggttgaa gaagcagaaa aattattaga actaaaaaat aaagaggaaa gtcttaaaaa
     2101 tgattttttt gcgaatatat cacatgaact taggacacca attaatgtta tttattctgc
     2161 tcttcaagtt caaaatggtt atttaaaaaa ggacaactgt aatgaaaatg tattaaaata
     2221 taatttgata attaaacaaa attgtctaag acttatgaga ttgattaata atatcataga
     2281 tataacaaga atagaaagta gtttttttat accaaactat aaaatagaga atattgttta
     2341 cttagtagaa gaaataacta tgtcaattgc agtctatgtt aaaagtaaga atattaaact
     2401 aatctttgat acagaggtgg aagaagccta tgttaattgt gattcgaatt tgattgaaag
     2461 aattatgctt aatgtgcttt caaatgcagt gaagtatgga aaagagggcg ggaatatttt
     2521 tgttaatatc tataaggatg gtgaaaataa tattttaatt tcagtgaaag atgatggtat
     2581 gggaatacca agtgacatgc aggcaaatat ttttgaaaga ttttcaaagg ttgacaacag
     2641 catatctagg aagatagaag gtagtgggat aggtttatct cttgttaagc agcttgtgga
     2701 aattcaacaa ggaactattg tttgtgaaag tgaattgaat gttggatcag aatttaaaat
     2761 aacctttcca actgtagaat attctttaga agatgtaaca gatgaggaac agttaaattg
     2821 ctattctaat aatgctatag aaactgctga aattgaattt tctgatattt attaataatt
     2881 agtaaaagtt aaaggtaata aacatttatg agtaagtgtt tattaccttt ttcatttaag
     2941 tacaaactat tgacaaatta tcccttgaac tttacaatgc ttccgaaata gataataaga
     3001 aatttgatta actaaatagt taattaaaaa taagaaggag atgatcagtt gtgaagggaa
     3061 aggttctcat ggcgacattc aaaaggaatt ttattgttat gcttagggca tatccaatga
     3121 gtttttttgt aggaaatctt ttaacagggt tttacacagt agtaggagca ttgtttatgt
     3181 acaagatgct ttttaacgga gcagttggga aggaattttt aggttacaca ggtactggag
     3241 attatatgag ctatgtaatt ttaggcagct taacttacat ttatgttgtt aggacatgct
     3301 taaatgtaag taggagtctt attactgagt taagggaagg taccttggaa agcttgatgc
     3361 ttgcaccttt taaaagggga gaatatttta taggaaatat gcttcagcag actgtcgcta
     3421 ctacctttga agtgagtata tctttaatta ttgctattcc ctttggtttg aatttaagca
     3481 gtgtaaacat atcagctctt attatttcag cacttttagg tttatatggt ttctttggat
     3541 tgtctatggt ccttgcttct ataatgctgt atacaagaga tacttatatt tcacaaaata
     3601 ctttatttgt aggaatgctt ttgctatgtg gtataacttt tccaacagaa tatttgccaa
     3661 cagttttaag gtggatggga gaattaatac ctgtaactga aatttcaaat ttagtaagag
     3721 gctcagtgct tttaggtaaa ggaatctttg agcagacaaa tacaattatt tatgtatttt
     3781 tattaagtac cgtttatatg ataataggat ttttaagtct taagaaaata gaatttatag
     3841 cattagaaaa aattcaagga taggtgataa gcatgataga agcaagaaat ttaaagaaga
     3901 tatatgaaac taaaattagt aaaggattat ttaaaagtga aaaagttaaa tttgaagcag
     3961 tcaaagacgt gtctataaaa ttaaaggagg gacagataat aggactctta ggtattaacg
     4021 gggctggaaa aacgactact attaagatgc tgacaacctt actttcccca acctctggag
     4081 aatattttgt tgatggaatt gatgcagtta aaaatccaat ggttataaaa aagaaaatta
     4141 atatggttgc tggtggggag aaaatgattt attttagact gactccacaa gagaacctat
     4201 ggtattatgg acagctatat ggaataccaa ataagcttct tcaagagaga attgattatc
     4261 ttcttaagtt ggttggttta tatgaaaata aggataaaaa agtagaggaa ttttctaaag
     4321 gaatgaagca aaggcttcaa attgccagag gacttattaa tgatcctcaa tatatattta
     4381 tggatgaacc aaccttaggc ttagatgcag taacttcaaa agagttgagg gaaaatgtta
     4441 aagtacttac taaagaaaga ggcaagggaa tattattaac ctcacattat atggaggaag
     4501 ttgaagaact tgcagattat atttatgttt tagataaagg agaaataatt aaacagggaa
     4561 cggttaagga attgtccaag gatgtattta caaaaataga atataaatta attcttcata
     4621 ataatataga aggttttgat aactatttgt ttaatatttt agccagtaag gatagcacag
     4681 ttgaagtata taatgatgaa aagacttaca aaatcataag ttcaagaaat ttaagtcttg
     4741 atatatcaaa agcttgtata aataaaggag caattataaa agaatattac gaaattgtac
     4801 ctaaccttga agacactata ataaaacttt caaagaaggg agcataattt atgaagacat
     4861 tttttaaagt ttgctccgca gaaatgaaaa aacagcattt aaattatttt cacagcaaat
     4921 taatctatgt ttcattattt ttatggccaa tacttaattt tataactacc tattatagtt
     4981 ttaagccttt tcgaataaat aatagtaata ttagctatct taatgaggaa aatgtggtaa
     5041 tatttatagt attaggatat atggcaatga gtttgtttag aagcttggtt caatcggctt
     5101 ggaacttttc ttttgaaaga ataagtggaa ccttggaatt aatttattta tcgccagctt
     5161 caaggcaggg ggtaatctta gggaatgctt tatcttcact ttttgaaagt gttgtattta
     5221 tggtactttt tacaatagga gtgctaatct ttaaaagaga ggttttgaat attaattatt
     5281 tagcattgat gatagttttt attataacct tagcaatggc agtagtatgg gggatgttat
     5341 tgaattcgat ctttttgttt tcaagagatt caggtttttt atttacaatc ttagaagaac
     5401 ctatggagat attttcagga gtaaaggtac caacctcagt atttccaatg tgggcaaagg
     5461 ttataagcct tgtgtttcca ttaacctatg ctattgaagc tgtaagaaag gttgtattaa
     5521 atggaagtcc tttaagtgaa atgaataatt ttattgttat tggcttagga ataataatac
     5581 tattatatat tgcatgtata caaataatta agctggttga aattcatagc agaaaaacag
     5641 gtgattttac ttatttttaa taagctttta attgtatatt atatatacta caaaataatt
     5701 gttcaaaacc taaagatatc ctaagaatat ctttaagctt tgaatagtga gttgtgaacg
     5761 ttgatataga tatccaaatt aataataaaa cttataaata aggtggagat agttaatgat
     5821 taaaaatgta gtctttgata ttggaaatgt attattaaat tttgaaccaa aagaatatgt
     5881 aagatctaaa gtcattgaag aaaaagttga agaaatatac gagagtattt ttaaaagtga
     5941 agaatggcca atgcttgata ggggaacaat tactgaagca gctgctaaag caaatataat
     6001 taaaagaaaa attgaaaatg aagagtttat taatgcagtt tttcaagatt ggtatgctat
     6061 tttgtcacct atagaaagca gtgtggatat attaaaaaaa ttaaaagaaa atgggtataa
     6121 gcttttttat ttatctaatt ttcatttggc tgcttttgaa tatgtaacta aaaaccatga
     6181 tttttttgaa ttatttgatg gaggaattgt ttcttataag gaaaagcttc ttaagccaga
     6241 aaaagaaatt tatgataaaa ttttagatac atataaactt gaaccaagtg aaactatatt
     6301 tatagatgat acagaagaaa atgttacagc agcaaggaaa catggtatac atggaattgt
     6361 attaaaagat cccaaagatt tacaagcctt attaaacgaa tttcaggtta aggtttgata
     6421 acttttatag tgaaaaggaa gctttatgaa gatagctgtt atttatgaaa aaggaattaa
     6481 aggtgagttt gtatattctc cacttaatga aatgttttgt gcaatgcaca tattgataaa
     6541 gcctgagcat catttgcata gaaataagtg gattcaaaag atagctaata atgaaaaaat
     6601 gttagaagct ataaaaaaat attctgatat tacagaggaa tattgcatag taatggattt
     6661 ttgtgcttat tttgaagaat gtacagagtt aaatatattg agtgctatag aatttttatc
     6721 acaagtacct cttaataaaa taaataaaat ctttaaagcc tatgataaaa gaatgaacca
     6781 aagccaatat aaagaattct tggaattgtt aaaaaggttt tatattgaaa tatttgcgga
     6841 agaattaaaa tatatagaac cgatgataac tagaatatta aagaaaaaag ccaaacttgc
     6901 agaagatatt ggaatcttta actttgtaga aactattcat gaaagaataa aggtggaaga
     6961 ggaaaaaata aaattctata agaataaaga atatgtggta aagaaagctg aaatcaaaac
     7021 aattaccata aatctatcaa cttttataag tcctcattta atgcttggaa taataaataa
     7081 taatttatat ttaacatatt tagtggaact agatacttat gaaaaagaaa gtcccaagga
     7141 tttagaaaga gctttaaaag ctttaggaga tggaaccaga ttacgaattc taaaagaaat
     7201 aagcagaaaa ggtaagagta cacaggaatt aagtacttta ctaaatatat cagaagcagc
     7261 ggtatctaaa gctttaaaac ttttgcaaga aggtgagcta gttaaaaaag aaagacaagg
     7321 aaattatata atatatactg ttaatacaat ttcaattgat tttattgctt ataagatata
     7381 tgaatatatt tattaaattc tcaattataa atgttcaatt attaattaat gttggaagtt
     7441 aaaaggagaa agttcatgtt tcttaacata aaatttggac attccctttt ggagagttga
     7501 tttttattta tgaatttatt aatttgcgat ataatattaa ttaaaactta tataaaagaa
     7561 tatatatgtt gaaaaagtat tattcaagaa ataaagattt ccaaaggaaa tcaacattta
     7621 tttataattg atgccctaaa agggtaccct gtggggtatt gaaccttgat aattgcaata
     7681 tatatatttg agaggagaca aagttcatga aaatagcaaa tggtgttgaa atgcttgaat
     7741 tagcagctaa aaatatgaaa ggtgaaccta catccattta tccaatatta atatgtgata
     7801 aggaaacaat tattttagtt gatgctggat atccaggaca attagagcaa attcgtaaag
     7861 aagtagaaaa aacaggcgta aaatttgaaa ctgtgaatat ggtgctaatt acacatcacg
     7921 atatcgatca tattggaagt cttgcaagta tagtgaagga actgcctgag gtaaaagtgc
     7981 tttgtcatga ggaagaaaaa gcatatattg agggagttaa gaagccacat aaattagcta
     8041 tgctagaagc taatttagat aatttatcac aagaaatgaa aggcttttat gaacatttta
     8101 aggttggttt tgaaaaagcg agaacaaaag ttgatagaac cttaaaagat ggtgaagagt
     8161 taccttattg tggtggcata acaataattt atacaccagg acatactatg ggacatagct
     8221 gcttatattt taaagaaagt aaaactctta tagcgggaga tcttttaatg gttaaagagg
     8281 gagttcttgt taaagctcct gagtcaatta attttaatga tgagttatgc ttaaaatccc
     8341 taaaaaagct tatgcaatat gatatagaaa atgtggtttg ctatcatgga ggcatatata
     8401 gcaataaagt taatgaacga ataaatgaat taatagaaac attagcacaa taaaatagga
     8461 agggcattag taaaattttg tctaaatata aacctacgaa aatttttcgt aggtttatat
     8521 tttaaattta attatttatg attggttata ataacattaa tgtaaattat agtaaaaata
     8581 taatgattaa attacaatta tatgttatat tatatataaa aataatagtt aagataaatg
     8641 tatggaggtg ctattacatt tttggtgatt actaagatat aaaaagtaga aatgaaaacg
     8701 ttagaatata tggttaagaa taagtagaat aaatgtattt ttattcaaat atttaacagc
     8761 tgatttaaat aaaagggaat tgatggatta ttcatcagca tagtacttaa aactcctagt
     8821 ttaaattgat atgagatctc aatggaatac cttttagagg cataatatta tttatttgta
     8881 agaaaaaaag tggataaata ttataaaaga tattataatg tatcatatta tgcattttta
     8941 actattatgg aatatattca aagaatttta ataattaatt gtgaatttta gggggagaca
     9001 tggcagaaac aatattacta gcattactat ttgcaaaaat aaggagatat gaaataaaac
     9061 ccctttttaa aacatggacg ttttatccta taatcatatt tgaaataatt tttttgtttg
     9121 gacagcttag tattttctta gggcattatg aatttattag ttttctgaaa agtttgaata
     9181 cattttattt ctgcacatac ttattattag tttttaaata tagaatatac cttcaatcaa
     9241 taataggttc tatttttatg cttataggtg gaggtttaaa tgatattgta ataaaagcta
     9301 atgatggctt tatgccagtt tttccgactt tatcctattt aacaggatat gctaaaactg
     9361 aagcatttgt tatagtaaaa gacattcata tgttaggaaa ttcacaaact aaactaaaga
     9421 tactaacaga ttttattgat ttaggttata gcattcttag tataggagac gtatttataa
     9481 gagcatttgt atttataata atctacaatt caataaagaa aattaataat caaaggagaa
     9541 aataaatgtt aaggttaaca gtgtttgaat ttatatttag ggggatgcca gaagcatttg
     9601 tagtaatgtt tgcaatgctt atgttatcaa atgcacgtat agatcgtaat agatacataa
     9661 tttcgagttt gttactggga tttggtgaat atggaatacg atttctacct ataagttttg
     9721 gagtacatac tatattaggc atatttataa tgattataat tatgtggagt atagataatg
     9781 tagatgttat ttttgcaata agatcttcat taatattaac tataactatg ttcataatag
     9841 aagggttaaa tataattgca ctaaagctta tttttaagga tgtatttgat acaataatgc
     9901 tagataccaa gttaaggaca ttaactggaa ttccatcatt aataatttta gtaataataa
     9961 gttatattat ttattattta aaaaaaagga agaattagat atgtttaaaa ttgaaagaat
    10021 atgtgaaaaa atttcaggat acatttctca agaattgaat tttgatgatg ataaaagggc
    10081 tgtaatcaat tatggaatat ttggtttatt tcaaacagga atgtgtatta tcttagttat
    10141 tttatttggg atatttttta atgtgacaat agaagcgctt atagtatctt ttactataag
    10201 tatcttaagg aaaagttcag gaggggttca tgcaaaatct ccaatgagat gtgcagttat
    10261 tggtacagct tcaagtattg gtatggccct attaagtaaa aatattaata tgagtttggt
    10321 tatggttata ttagttggaa gtgtaatttt catatggtca tactatatta taaataaaat
    10381 tgcaccagta gatagtatag caaaacctat taaaaatatt gaaaagagga aaagattaaa
    10441 aggaacttca attaaaacct tgagctttta tttaattact ataataacta ttattttaag
    10501 ttatctatat ttagaaaatc gaaatttatt aggttacata ttatgtgttt atatgggttt
    10561 gttatggcag gtattttctt taactaaatg tggacatatt gtattaggca agttgggata
    10621 attaaaatta atcactgagg ggaggtgaaa aaatgaagag taaaatttta atgggtatag
    10681 ctacaatagc aactgttttt gcttcaattg tagctacttc agcatgttgg tatgttcatt
    10741 atcaacctga agagccaaaa tgcttgagag atgaataaat tgaaaaatga gaccaaatta
    10801 ttggtctcat tatagtaagt ataaggggca gtgtatgaaa aaaataataa ataataaaca
    10861 aaaacaaatt aatgatatag tttcagtagt taaattgtct acacttttgc ttattggtat
    10921 aattttatct aaaacatttg ttaaaaataa ctcggcaata tgggaatcta gtacttttta
    10981 tattctcata attttattta taccattaat gctcttcgtt ttagtatact tagcatggtc
    11041 tttttcagtt gaaaataaaa ttaagaataa atatagaaat atttttaata taattgaaat
    11101 aaatttcttt ttaattgtat tttccgcaat tatatgggta tgtggagtaa atggaagtca
    11161 atataaaatt ttgtacttat ttataattat aacgacaaca attcaatacg gaatgaagcg
    11221 tggattaata gtttcaatca tatcgtcatt aattatttta gggatggata ttatggttgt
    11281 cccaaatgct tacttaaatg atttttttca agatgattta attttggtag gaatttttat
    11341 tttaacagca tggcctttgg ggttttatgt aaaaatagaa ggtgaacata ttaaaaggtt
    11401 agaagaacaa ataaatattg atgggctcac tgaattatat aatcacagat atttttgtga
    11461 taccttaatt gagaaagtta aagctggaga aaggaataat aaacctgtat ccatgatttt
    11521 tatagatata gattatttta aacaatacaa tgatacatat gggcatcaaa aaggagacta
    11581 tgtacttaga aaagttgcag aaattattaa aggaaatata agagaaggag atctttcagc
    11641 taggtatgga ggagaagaat ttgcagtgat tctacctgat actaatgaga aagaagcctt
    11701 gaatcttgct gagcatctaa gagaacgaat agaaaataca tattttgaag gagaagatag
    11761 tcagccgaat ggtaagatta ctgcttctat gggagtatct gtttatcctg ataaagcaaa
    11821 agatgatata gaattaataa aaagtgctga tgatgcttta tacagggcaa aatttataaa
    11881 taagaataag gttgaatcat atacttctat tttagatgag attaaaagca acattgatga
    11941 aaaagatgtt gaacttgtta catctataaa aactttaatt agcgttatta atgctaaaga
    12001 taaatataca tatggacacg tagaacgtgt ggtaatttat agtaggctta ttgcagaaaa
    12061 gcttcagcta agcaaaagaa ataaagaaat tttgatttat ggtgcatata tgcacgatat
    12121 tggaaagata aatactagga aagaagttct agtgaaaaag atgaagctta cagatgagga
    12181 atgggaggaa cttaagcagc atcctgccaa tggggcagag ataatcaagt ctgttgaatc
    12241 tcttaaagaa attactccat taataataag tcaccatgaa agatatgatg gaaaaggata
    12301 tccgaatagg ttaaaagggg atgaaatacc tttccttgca agaattctta cagtagtaga
    12361 tagctttgac gccatgactt caaatagacc atataataca agaaagtctt acgaagatgg
    12421 aatacaggaa cttgaaagat gcagtggaac acaatttgat cctgagattg taaaagcttt
    12481 tgttgaagta gttagaaatg acatagaagt gtcagattta aatggtatga acagaaagta
    12541 tgccaattaa atagttgttt ttaaaatgat gattggaaat taaacattta attggcatat
    12601 tattaaaacc accagaaata gcttggttgc tattttggcg gtttttaata tataaactaa
    12661 agtaaagtat caacaccatt tacattagct tgttcatttt catcaattgg aataacaata
    12721 catttctttc catcaattat ttgtgatttt atttgagcta ctttttgagg ttttacttga
    12781 agaataatgt cataatcaga atttgattct tcttcaacag ctaattcatg attagaattt
    12841 tgttcaaaag ttctatctga atcgtcatct aatttaatat cagtctttgc ttctaaaatt
    12901 gtatctgctg ctgattctaa agaactctct ttttctatgc tttcttcttt ttctgaaact
    12961 aattgagagc tttgttttgt ttcttcaagt ctttcttcaa gaaatttgac tttcttctca
    13021 agtctttctt ctttttttct ttgctcattt gctgtaagtg cttttttatc aattaaatga
    13081 tcaactatag gaggggtatc cccaaatacg tctatatagg atttttcaat cttagcagtg
    13141 atttcttctg aaattccact ttccattaaa agatcttgaa tattatcatt tgatagaagt
    13201 ataggttcag catttttgcc attaacagca atgtgttctt ctgccatgct actaagagtt
    13261 tcttgaattt ccataaataa atgttctgat ttttcctcgt cacagccaac agctttacta
    13321 atgatagttt ggaatttttc cttctgttca gttgcagttt cttttgaact gcagcctaaa
    13381 acttcttcca ttacttccgg atgtgagtct tttgcgtttt ttgcatagta tataatagaa
    13441 tgaatatcag tgcttcgatc tataaaagct ggaaatacaa atccaaggtc aggaactcca
    13501 actatccagt ctctaatacg tgctccaatt ttatgttcat cttcaagata tccaagagca
    13561 ggttttgcaa gttctactgg acaaattgca cataaaatat attcgtaaac ttcttcagat
    13621 tcatctaact tagaattatc tgtagtcctt gtcataacat cataagcatc gtgaaaaaga
    13681 agtattagaa aattaccagt atagtcatag ctatctataa ttttattgta gaagtcatca
    13741 agcttcgcat catcttttaa tctgctcttt ttaagctcca ttagagaaag ttggtggctt
    13801 cccatacctt cttcctctaa agggaagtta agctctaaaa gattattgcc aattgttcca
    13861 gatagggtct ttttagcaat ttctagatat ttataaaatt cttcatctct taaatttaaa
    13921 aaagtttcct taagttttaa tacaatattc ttttggccat ctacatagca gccacacatt
    13981 ctggtaaatg tacaatcatc cttttttaaa cgtcttttca attctaatat gtcttttttt
    14041 ctcatatagc gcccttccat ttcgtgaata ttaatttagt acataataag aatatgttac
    14101 ctaatatagt atagttcgca attaaatagc atgcaagtat ataaattaat ttctaatatt
    14161 aatgcctcat attgaatgta aatgaacatt tatattttaa aactttgaat agtgattttg
    14221 tcccaaacaa tgtttatttt aaactaaatt gttatgtaaa aagttttttg cataacaaaa
    14281 ttagacatgc aattatatta caaaaaataa atatataatt atgtttaaaa gttgtaaaaa
    14341 acaagtaaat attaaaagga aaaatgttga aagtgtcgaa ttttatttat aggaatatat
    14401 atggtaaaag aggagagggc aatatatgaa gaagagtatt ggtgggataa agggtagaat
    14461 tttaatagct acagttttag ttgttttaat aactgtagta agtattagtg gtatttcaat
    14521 ttatcaagtt aataaaaaga attacagtga ttatttaact aattctaagg gacaaatgaa
    14581 cacagtttcc caggcaatta aaattttcta tgaccaaata gataaaaacc tcgatatgct
    14641 tgcaacaaat cctttagtaa tgtcggcaga taatactata acaagttata aaggtacaac
    14701 agaagaaact caaatgaaac cttctgctaa tggagaactt gaaaaagcaa tttacaaagt
    14761 atttgaacaa tatggaaata gccatgaagg aacaaactat gtatatttag gcactaaaga
    14821 tggaagatat atacaatggc ctgaaactac aacctttgca ggctatgatc cagtaataag
    14881 accttggtat gttcaggcta aagataaaaa tggaaaaatt attagaacag agccatatac
    14941 ttttaagtct gaaatgctta caagtaatgc acgttcattt acagataaag atggaaactt
    15001 tattggagct ataggtcttg atgtgaagca atctaaaatc agtgaaatgt taaatcaaat
    15061 gaagattggt gaaactggat tttcaatgat aatacatact acaggtgcta taatggcaga
    15121 cgggaaaaat cctgataata attttaagaa agtacaagaa attggaattg ctggcttgga
    15181 tagactttta actgatcaaa caaatgcatt tgaggttgta atcaatggtg aaaaatatct
    15241 tgtaaatcct tataaagtag aaggtaccga ttggatttta gcatcgctca taactcaaaa
    15301 agagttaaca ggtaatgcaa gagaaataat gaaggtggta attatctcag cattgataat
    15361 actagtatta gtaagtattt taattaattt tatttctagc agtataacaa aacctatagt
    15421 agccgttaca ggaagagtaa aagaatttgc taatttagat ttttcatcaa ctaatcagtt
    15481 aagttctgct tacataaata gaaaggatga aactggtgag atgataaggg ctcttaaaat
    15541 tatgagagaa aatgtagcag actttattcg aaaagcagcg gatacaacgg aacacattgc
    15601 tgcatcatca gaagaactaa ctgctacttc agagcaagca gctactgcat cagaagaagt
    15661 tgcaaaaact attgaagaaa ttgcaaaagg agcttcggat caagctaagg atacagaaat
    15721 aacagctaat aacatagggg aactaggaac tttgttagag aaggaattaa attatacaaa
    15781 agaacttaac gtggcagcag ttcgaattga aaagcaaaaa gaagatggtt tcttgatttt
    15841 aaaagaactt atcaataaga cacagaaaaa tagtgatgca tctagtaatg tttataatat
    15901 tataatgagc aataatgata gtgcagaaaa aattaatagt gccagcacta tgattcaaag
    15961 cattgcagaa caaactaatc ttttagcttt aaatgctgca atagaagcag caagagcagg
    16021 tgaagcaggg aaaggctttg cagttgttgc agatgaaata agaaaacttg cagagcaatc
    16081 aaataatttt acaaatgata ttaaaactat aataaatgag ttaaaaacta aatctcaaaa
    16141 tgcagttgat ttaatgcagg aaacaaaata tgttgttgag gaacaagcta ctagcgttaa
    16201 agaaactgaa ggaaaattta aaggaatagc cgaagcaata gatataataa aaaatataat
    16261 tgaaaaactc aatcagtcta caagtttgat ggttgaaaat aaagataaaa ttattgattt
    16321 aacacaaaat ctatcagcaa tttctgaaga aaatgctgca gcaacggaag aaacagcagc
    16381 atctatggag gaacaatcag caacaatcca agaaatagct agtgcaggtg aaaggttagc
    16441 tacaattgca gaagagttaa aggtatcaat agataaattt aaattttagt ttcaaagata
    16501 aattataaaa ttagtgaaaa agcaaactac ttaatcaact agtagtttgc ttttttagtt
    16561 ctaataattt aagaaatgaa ttatggttaa taagatgtaa tacaatattg tattaatcaa
    16621 tgcgatattg tattgattaa gaaaacgttt aaacaagttg attaataagt ttttttatta
    16681 attttaatac atttttgtat taaaaaatgt actatttcta ataacgtttt caaaaaagta
    16741 atgttaatta aagttgaaat ttaaatttat tagcagcaag aaaacaagtg aaataggggg
    16801 acttagagat aaaacaaaga ataaaaaagc ttcaataata aaagttggca tgctaattgc
    16861 tttaaatatt agtgttgaaa gatacagagt aagaagaagg tgtattaagt ggacaaggtt
    16921 aaaagtatcg atgaagtaat ggaatatatc aaagatggta tgactattat ggtaggtggt
    16981 tttatgggag taggtactcc tgaaatgctt attgatgcaa ttgttaagaa aaatgttaaa
    17041 gatttaacta taattgccaa tgatactgga cttccggata agggagttgg aaagttagtt
    17101 gtaaataagc aggttaaaaa agtagtagca tcccatattg gattaaatcc agaaacaggg
    17161 aagcaaatga atactggaga aatggaagta gatttagtac cacaaggtac tttagctgaa
    17221 agaattagat gtggtggagc tggaattgga ggttttttaa ctgaaacagg cataggaaca
    17281 gctgttgaag aaggaaaaca aaaactgaaa ttaaatcaca aagaatacat tttagaattg
    17341 cctttaagag cagatatggc actagttgga ggttcagtag tagataagaa ggggaatatt
    17401 ttctataatg cttcaacaag aaatttcaac ccattaatag caactgcagc agatttagtt
    17461 attgttggag ctgaaaaaat agttgaggtt ggggacttag atccaaatca tgttatgaca
    17521 ccaggtattt ttgttgatta tattgttgga ggtgacaatt aatggatagt aaaaatgcaa
    17581 aggagtttat tgctaggaga atagcaaaag aacttaaaga tggggatgtt gtaaatttag
    17641 gaattggatt gccgaccatg gtagcaaatt atttaccaca tggaattgat gtgacatttc
    17701 aatcggaaaa tggttttgta ggattaggca atgcgcctga agagggaaaa gaagacaaag
    17761 atatagttaa tgccggagca cagtatgtga ctattaacaa tggggcagct ttttttgaca
    17821 gtgcaacctc ttttggaata attcgtggtg gacatgttga cgttactgtt cttggagcct
    17881 tggaggttga tgaaaaaggt aatcttgcaa attatatgat accaggaaag atggttccag
    17941 gtatgggtgg ggctatggat ttagtaagcg gtgcaaagaa ggtaataatt gcaatgcttc
    18001 acactgcaaa aggtgaatca aaaatactta aagaatgtag acttcctctt acagctgtag
    18061 gcaaggttag tttaattgtt acagatatgg ctgttatgga agtcacgaaa gaaggtcttt
    18121 tattaaagga aatagcagaa ggtttgacag ttgaagaagt attaaatgca acagaggctg
    18181 aattaattat acctgacgac ttaagagtca tagcagttta aagtgaaact tgatttagat
    18241 ggggaaccca tcgaaatctt agttgaactt ataccctcaa ggggtaccca gtccaggagc
    18301 atgcagtcgt taactttcaa ttaaataagt gggagtgtta cgaatgctag ctatcggata
    18361 ataatatttt aggagagtga tttaaatgaa aaaagtagaa ttaaaaaatg tagctccata
    18421 caatgctcca aagcattttg atatgaaggc aatgaaatta cacggagaag cagaaacagg
    18481 tgcaaagcaa ttttggatgg gaatgtcata tttcttacca ggtggaggag cagaatatgc
    18541 ttatgaagat tctccaactg aaaagattta tttcgtatta gatggtgaaa taacagtaaa
    18601 atcaaaagat gaaacttttg tacttaaaaa ggatgattct atctttattg gaccaaatga
    18661 aggcagagaa atgattaatg aaacaaataa agtagctact gttttagtag tagtaagcaa
    18721 taattaatat atttctaaag acccaattag caggaaggtg gagaaaaaat ggattctaaa
    18781 tttattaata atttatttga tgttaaagga aaagtagcag taataactgg tgcaacaggt
    18841 gctttaggaa aagctgtttc ctttggatat gggttagctg gcatgaaggt ttttgttaca
    18901 ggaagaagtg ataaaaagtg ccaagaactt tgcagtgaat tagaagctca aggaattgaa
    18961 tgtggatatt ctacaggaga tccagcagtt gaagctgatg taaaaaaagt tgttaatgat
    19021 gcagtaggta aatttggtga aatcaatgtg ttagtaacag cagcagggta taataaccct
    19081 caaccaatcg ttgaacaagc tttagaggaa tggaagaaaa tcatggattc agatgttcaa
    19141 ggtacatggt tattctgtaa atatgttgga gaaaaaatga tcgctcaagg taagggtgga
    19201 aaagttatac tagtatcttc agctcgttct aaaatgggaa tggcaaatta cacaggttac
    19261 tgtacagcaa aaggtggtat tgaccttatg gctcaatctc ttgcttgtga atggacagca
    19321 aaatataaaa tcaatgttaa cacaattaac ccaacagtgt tccgttcaga tttaactgaa
    19381 tggatgtttg atccagaaag tgctgtttat caaaacttct taaaacgtct tccagttggt
    19441 cgtcttggag aaccagaaga ttttgttgga ccatgcatct tcttagcatc aagtgctagt
    19501 gactttatga caggagctaa tgttgctact gagggtggat attgggctaa ctaataaact
    19561 aataagtatt ttataaaata atgtttccat aaggcaatta aactgacagt aatgtgattt
    19621 ttataaaaat attaattgaa aaattattaa tacactcata atcttttaaa aaggcagcta
    19681 tgctgcatat agaaataatt aataataaat gatatttgga ggaatttaaa atgggaaaaa
    19741 aaatatatgt agatttaact catcctttta gtgcagatat accaagatgg ccttatttcg
    19801 ttaagccagt aattgattct atgcatactt tagccaaagg tggagttctt acacaaagaa
    19861 tagattgtgt tcaacataca ggaacacact gtgatgcacc acgtcatgtt atggaatatg
    19921 aatttgatgg tagacgtgct cgttacactc atgaaatgcc agtagatgca tatatgggag
    19981 atgcagtatg tttagaaatc aacattgaac cttggggatt aatattgcca gaacatcttg
    20041 aagatgcttg taagcgtgca aacattaagc cagaagaatt agaaggaatg gtaatttgct
    20101 taaatacagg aatgcatcgt aaatttgatg attcaaaaga atactatcat tactcatgtg
    20161 gtacaggtgt tgaagctgga aaatggtttg taaaacataa agttaaatgt gtggctatgg
    20221 atatgcaagc tttagatcat ccacttcata ctgctatggg taataatggt ggtactcgta
    20281 tgaacttaat aggtaattca ggaagatcta ttacagaaga atataaggaa aaattcggcg
    20341 aagaagcata tgctgaattt gataaagatg aatatatcag aattcatggt aaagaagcat
    20401 atgatgctaa atttggtgat ttagaagcaa ttggctgctg gggaacatgg gaaccatgcc
    20461 ataagcaaat gttaggacat ggtattgttg gagttgaaaa ccttggtgga aatttagata
    20521 aagtatcagg aaaacgcttc agattcttat gtatgccaat tagatggtac atgggagatg
    20581 gatcaatggt tcgttgcgtt gcagaaatcg atgaagatga tgtaaatgat gtaccagata
    20641 gaacttatac ttacggggga ttttaggcag tttacagttt acaatttaca gttcacagtt
    20701 tatgcgcttg aggggatctt gtgagtagtt tacggttggt gaacaattta attattaata
    20761 aagtaatttt gaggatgc
//
