LOCUS       NZ_KB907788.1          24624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB907788.1 Dyadobacter beijingensis DSM 21582
            H144DRAFT_scaffold00003.3, whole genome shotgun sequence.
ACCESSION   NZ_KB907788
VERSION     NZ_KB907788.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:10:29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 208134
            Orig. end    :: 232758
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24624
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[218134:222758]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14624
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..24624
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03882))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03882))"
                     /tool="antismash"
     CDS             complement(139..1050)
                     /locus_tag="ctg3_160"
                     /transl_table=11
                     /translation="MNTEQSNPLLCDIESGICEMPGNNADTAATTAATAHNVLKIIYFT
                     DPICSSCWGIEPQLRKLKMEYGRYFDIEYRMGGLLPDWSYNSGGISKPSDVAHHWDEVS
                     HYYDMPIDGDVWLEDPLHSSYPPSIAFKAAQMQDAAKAVRFLREIREMVFLRKQNITQW
                     KHLATAAGNVGLDLQQFEADYHGHAKSLFKEDLDLGAQLGVRGFPTLFFADRNGGLEKV
                     YGTKPYEVYEAALRRQLPSAVKSPIDTGWQKLFTRYRTLTTREFAELSQTPREDSEAFL
                     QKLVESGSLSRLITKNGTLWIN"
     PFAM_domain     complement(355..924)
                     /aSDomain="Thioredoxin_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13743.8"
                     /description="Thioredoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_160_0001"
                     /evalue="1.20E-58"
                     /label="ctg3_160"
                     /locus_tag="ctg3_160"
                     /protein_end="232"
                     /protein_start="42"
                     /score="198.0"
                     /tool="antismash"
                     /translation="YFTDPICSSCWGIEPQLRKLKMEYGRYFDIEYRMGGLLPDWSYNS
                     GGISKPSDVAHHWDEVSHYYDMPIDGDVWLEDPLHSSYPPSIAFKAAQMQDAAKAVRFL
                     REIREMVFLRKQNITQWKHLATAAGNVGLDLQQFEADYHGHAKSLFKEDLDLGAQLGVR
                     GFPTLFFADRNGGLEKVYGTKPYEVYE"
     CDS             1284..1589
                     /gene_functions="regulatory (smcogs)
                     SMCOG1167:transcriptional regulator (Score: 72.3; E-value:
                     3.1e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_161"
                     /transl_table=11
                     /translation="MENTEEGQGQCPAETLLKQLAGKWKPQIFRIALAGPVRFNALLRQ
                     LDGSSKQAIASALKEMEEQQLIEKQVIKLKPLHIEYILSERGRSLIPIFRQLEHLA"
     PFAM_domain     1341..1580
                     /aSDomain="HxlR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01638.19"
                     /description="HxlR-like helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_161_0002"
                     /evalue="2.60E-17"
                     /label="ctg3_161"
                     /locus_tag="ctg3_161"
                     /protein_end="99"
                     /protein_start="19"
                     /score="62.5"
                     /tool="antismash"
                     /translation="LAGKWKPQIFRIALAGPVRFNALLRQLDGSSKQAIASALKEMEEQ
                     QLIEKQVIKLKPLHIEYILSERGRSLIPIFRQLEH"
     CDS             1871..3076
                     /locus_tag="ctg3_162"
                     /transl_table=11
                     /translation="MSDFLDLQNGWYNGLIQGLGQSQDSFQIIQPAPPIASGTAANPTF
                     WAYYNNIPPQSLTAQFVASGGNQFYSNYRGLLSALEPSRNINVKEDIGEANFLAWQAYV
                     QTQPTPSMNQIPTMFRNWAMFNAPEVANIGSSDYAAILLDPIATAQNELTLVYTTPAGL
                     PINFDWQLNYADMVNQLASAPSRSFSFDSSTMNKNVSGSWAGSSKSGFFGLWGGSSSTS
                     SLSEQFASSRIQVSASFEHILVLPNTPGAWYYSSAMGLAFANKTGSPWRDKAAINWNNT
                     FGPDGNMQYFSANVIVASGMSITVTSDASYSSLDQQTITSSGSSGFWPFYSGDSGSSST
                     NRVTFNQDGHMTITTSSIPGVPVVVGVNVLSAGEFVGHSSSLGVSLFESAKAFAAESLA
                     TV"
     CDS             3148..4272
                     /locus_tag="ctg3_163"
                     /transl_table=11
                     /translation="MMATDTSTDAVTALTDAWYNQLAASLSLSVRNFQLLQPPAVPTGD
                     QSLWDSFNVVPPVTLKYNRWVYQQPAFFKQYAALVNSLSFPESAFVEDIGADTYVQWTA
                     YLKTVSPPPAPNELPGVWFQWAMLHAPSVANIGRSDLATQLLIGGAQAALEPYEGPDAK
                     QADYSPSFGDLKNILKLSSGASFSFDSSTADPDVSGSWVPGDDPNYFGVWTGSSTAFRI
                     SRKFALSKITVTAAFDHFGVVPVTPGPWYNSSMLHLAWVSGASVPPWVSESDWDRYFGA
                     SGKLTHAIGSVLAADGITLTLHSDANFSPEEQAVIRVLALMGDWPVYCPVQLSAITNTV
                     TSAPGSLTIRFHAAPGNPVILGYNVFDIRSYTGA"
     CDS             complement(4278..4724)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1298:putative carboxymuconolactone decarboxylase
                     (Score: 62.2; E-value: 7.4e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_164"
                     /transl_table=11
                     /translation="MKTRVDVAATQPQAYKAMYGLEQYLSASKLSKTHRELIKIRASQI
                     NGCAFCIDMHTKDALKAGESIQRIVLLNAWRETALFTPEERVILALTEAVTLIHRGGVS
                     DELYAQASALLDEEYLAQVIMAIATINTWNRIAISTTMQPAAAA"
     PFAM_domain     complement(4446..4691)
                     /aSDomain="CMD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02627.22"
                     /description="Carboxymuconolactone decarboxylase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_164_0003"
                     /evalue="9.20E-21"
                     /label="ctg3_164"
                     /locus_tag="ctg3_164"
                     /protein_end="93"
                     /protein_start="11"
                     /score="73.8"
                     /tool="antismash"
                     /translation="PQAYKAMYGLEQYLSASKLSKTHRELIKIRASQINGCAFCIDMHT
                     KDALKAGESIQRIVLLNAWRETALFTPEERVILALTE"
     aSDomain        complement(4494..4643)
                     /aSDomain="TIGR00778"
                     /aSTool="tigrfam"
                     /description="ahpD_dom: alkylhydroperoxidase AhpD family
                     core domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_164_0001"
                     /evalue="5.20E-21"
                     /identifier="TIGR00778"
                     /label="ctg3_164"
                     /locus_tag="ctg3_164"
                     /protein_end="77"
                     /protein_start="27"
                     /score="71.9"
                     /tool="antismash"
                     /translation="SKLSKTHRELIKIRASQINGCAFCIDMHTKDALKAGESIQRIVLL
                     NAWRE"
     CDS             complement(4793..5383)
                     /locus_tag="ctg3_165"
                     /transl_table=11
                     /translation="MDFPENAGRALTEHIKAIAGLPTDTTGGVLDFFRYRQVAKKEVVQ
                     QADRECTTLYFVVRGCLRMYFADSKGVEHTTQFALESWWLTDFLAFEKKQQTGFAIQAV
                     EPAEVLSIDRQSYHAMLDAFPRMERYFRILYQYGYGAAMLRMKYQQDMSREALYRQFAG
                     LYPDFVQRVPQYLLASYLDITPEYLSELRKKRS"
     PFAM_domain     complement(5018..5278)
                     /aSDomain="cNMP_binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00027.31"
                     /description="Cyclic nucleotide-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_165_0004"
                     /evalue="6.90E-10"
                     /label="ctg3_165"
                     /locus_tag="ctg3_165"
                     /protein_end="122"
                     /protein_start="35"
                     /score="39.0"
                     /tool="antismash"
                     /translation="RQVAKKEVVQQADRECTTLYFVVRGCLRMYFADSKGVEHTTQFAL
                     ESWWLTDFLAFEKKQQTGFAIQAVEPAEVLSIDRQSYHAMLD"
     CDS             5477..6448
                     /locus_tag="ctg3_166"
                     /transl_table=11
                     /translation="MQKKFDLKSFNLYQFLKHQNAHNFHTPFFLADKDTYRHAHVNFPF
                     RTFAYGLGVTYSGDGDTFKIGSTDYTVGAHCLTTIGPGLVCQWAGNYTAEHDTVYFTEE
                     LFRDIRTNAFLQSLSFFFHGGNHVIRLTEAQTAKMRSLFEVLKELKNDNEAVPGIVYSL
                     LKLADSFHGAAHAASDGNRVNTGLGNGTGSIESNADHASGDAPAPPANRASSRISSKQK
                     ITRAFRKLVAEHFPEHKEVAHYATELNITPKYLSEILQAELGKPAKTFIDEHVLMEAKS
                     LLKQTTFSVQEICYWLGFEDASHFTKWFRKQAGVTPTEYRKE"
     PFAM_domain     6206..6442
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_166_0005"
                     /evalue="6.90E-21"
                     /label="ctg3_166"
                     /locus_tag="ctg3_166"
                     /protein_end="322"
                     /protein_start="243"
                     /score="74.4"
                     /tool="antismash"
                     /translation="YATELNITPKYLSEILQAELGKPAKTFIDEHVLMEAKSLLKQTTF
                     SVQEICYWLGFEDASHFTKWFRKQAGVTPTEYRK"
     CDS             6541..7659
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262:haloalkane dehalogenase (Score: 46.9; E-value:
                     3.5e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_167"
                     /sec_met_domain="PF00561 (E-value: 4.8e-13, bitscore: 45.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNAEAFEVAVSQQVLDDLKNRLQNTRWPGEADGSGWAFGTSEAY
                     LKELTQYWLHTYDWRKQEEALNRYPQYIADVNGVQVHFQYIKGNGANAKPLLLTHGWPD
                     SYYRFHKLIPLLTEGEQPFDLVIPSIPGFGFSEKTALSSTAVADLWKDLMTQTLGYEHF
                     YAAGGDIGMSVTKALASKYPGIVAGVHFTDIGYPMGQEDPATMTEAEQQFAQFVQQWWY
                     SEGAYAMVQATKPQSLAYGLNDSPVGLAAWIVSFGNAGAHPDILEKAFGGRDALLTNIM
                     IYWVTQTIATSARIYKVDAMAQWSGEKPLEKSDVPAGIAVFPREAQFPKEWAERFVHVV
                     SFRAMDEGGHFAALEVPEIFAAELKRFFSELH"
     PFAM_domain     6553..6867
                     /aSDomain="EHN"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06441.14"
                     /description="Epoxide hydrolase N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_167_0006"
                     /evalue="2.90E-32"
                     /label="ctg3_167"
                     /locus_tag="ctg3_167"
                     /protein_end="109"
                     /protein_start="4"
                     /score="111.4"
                     /tool="antismash"
                     /translation="EAFEVAVSQQVLDDLKNRLQNTRWPGEADGSGWAFGTSEAYLKEL
                     TQYWLHTYDWRKQEEALNRYPQYIADVNGVQVHFQYIKGNGANAKPLLLTHGWPDSYYR
                     F"
     CDS             7723..9282
                     /locus_tag="ctg3_168"
                     /transl_table=11
                     /translation="MLAMVAAIVLLNMWATKLKVAYPILLVVAGLLVSFVPGLPVLKIN
                     PDLIFLIFLPPLLFEAAWSVSFKEMRKWWRIIGSFAFLVVFFTAFSVAITTTYLIPGFT
                     IALGFLLGGIVSPPDAVSTGAIMKFVKIPKSTVAILEGESLLNDASSLIIFRFALAAVA
                     TGHFVWQQAATSFLWMVAGGAGIGLALAWAFVQAHRRLPTDAPSDIALTLIEPYVMYWV
                     AEELHSSGVLAVVAGGLFMSARRLSFLSSTSRIMGYSVWESFVFILNGVVFLIIGLDLP
                     EIVEGLRLEGVPLRTAIGYGVLVTLVLILARMISSYAAMIATLIFRPSVAPRARSNRAR
                     FKMPLLLGWTGMRGVVSLAAALSIPVALDNGAAFPQRNLILFITFVAILLTLVVQGLTL
                     PAFIKRGKLFEAFTEDSEQEAMQKIKRGLRQQIYHFLQHRKNDGLHEEMAVRKILQHWE
                     EKAKSSDDEWMNDQTKAILLEMLECQRTYLAELNKDISVNEDYIRRQLYQIDLEEERLR
                     MI"
     PFAM_domain     7726..8934
                     /aSDomain="Na_H_Exchanger"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00999.23"
                     /description="Sodium/hydrogen exchanger family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_168_0007"
                     /evalue="2.40E-52"
                     /label="ctg3_168"
                     /locus_tag="ctg3_168"
                     /protein_end="404"
                     /protein_start="1"
                     /score="178.1"
                     /tool="antismash"
                     /translation="LAMVAAIVLLNMWATKLKVAYPILLVVAGLLVSFVPGLPVLKINP
                     DLIFLIFLPPLLFEAAWSVSFKEMRKWWRIIGSFAFLVVFFTAFSVAITTTYLIPGFTI
                     ALGFLLGGIVSPPDAVSTGAIMKFVKIPKSTVAILEGESLLNDASSLIIFRFALAAVAT
                     GHFVWQQAATSFLWMVAGGAGIGLALAWAFVQAHRRLPTDAPSDIALTLIEPYVMYWVA
                     EELHSSGVLAVVAGGLFMSARRLSFLSSTSRIMGYSVWESFVFILNGVVFLIIGLDLPE
                     IVEGLRLEGVPLRTAIGYGVLVTLVLILARMISSYAAMIATLIFRPSVAPRARSNRARF
                     KMPLLLGWTGMRGVVSLAAALSIPVALDNGAAFPQRNLILFITFVAILLTLVVQGLTLP
                     AFIK"
     aSDomain        7726..9270
                     /aSDomain="TIGR00831"
                     /aSTool="tigrfam"
                     /description="a_cpa1: Na+/H+ antiporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_168_0002"
                     /evalue="3.20E-94"
                     /identifier="TIGR00831"
                     /label="ctg3_168"
                     /locus_tag="ctg3_168"
                     /protein_end="516"
                     /protein_start="1"
                     /score="314.3"
                     /tool="antismash"
                     /translation="LAMVAAIVLLNMWATKLKVAYPILLVVAGLLVSFVPGLPVLKINP
                     DLIFLIFLPPLLFEAAWSVSFKEMRKWWRIIGSFAFLVVFFTAFSVAITTTYLIPGFTI
                     ALGFLLGGIVSPPDAVSTGAIMKFVKIPKSTVAILEGESLLNDASSLIIFRFALAAVAT
                     GHFVWQQAATSFLWMVAGGAGIGLALAWAFVQAHRRLPTDAPSDIALTLIEPYVMYWVA
                     EELHSSGVLAVVAGGLFMSARRLSFLSSTSRIMGYSVWESFVFILNGVVFLIIGLDLPE
                     IVEGLRLEGVPLRTAIGYGVLVTLVLILARMISSYAAMIATLIFRPSVAPRARSNRARF
                     KMPLLLGWTGMRGVVSLAAALSIPVALDNGAAFPQRNLILFITFVAILLTLVVQGLTLP
                     AFIKRGKLFEAFTEDSEQEAMQKIKRGLRQQIYHFLQHRKNDGLHEEMAVRKILQHWEE
                     KAKSSDDEWMNDQTKAILLEMLECQRTYLAELNKDISVNEDYIRRQLYQIDLEEERL"
     CDS             9436..9993
                     /locus_tag="ctg3_169"
                     /transl_table=11
                     /translation="MKNDVKKLLIAAAGAVTVPLLLTALALWQWKPGAPMLAVVLLLGA
                     VALVYDLVAKRKLNSHAYRFALGIAILTVLALLWMNVAVGGILGDNPANMMYFGVLITG
                     LAGAVIARLEAVGMAFALFAMAFAIVLIPIIAWAIGTPAFANGFPAVMGLHAGFALLFC
                     GSGTFFLRAARGQRTRHMSTGA"
     CDS             complement(10001..11164)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_170"
                     /sec_met_domain="LANC_like (E-value: 1.4e-15, bitscore:
                     52.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAAAKIDEIHEVINIYRRQLTSFSLSEGYLGVSVFKYLYAVHTG
                     RKRYLDEAREAFDHACDMIDGDPRKAYPQDFTDLGSVAQYLCQAGVLDIDPNVFLSDVD
                     SILLSKMRAELSAGNIGSLTSGALGYGLYFLQRSYYNRERAQPVVEELVLGIIRSAVRT
                     DGTCHWNAGLDHDEAGSGLFFPQGEAAILLILSRVVEMGLFPATHLEALTQEAIAYIEN
                     RHLEQKALSETDKNYGVYLNRQASRYEDISLGYTLLRTGTAFKNAEWSKEGRAILKNCA
                     SRHLIDPTGVQNAGILSGATGLALLFDRAAHLTNDVAMEHAANFWYTQILRFDLNADGY
                     AGYKVLENPWSPQSNIAFSEGIIGIGCGLIKSLNPGKVDFHDLIWLL"
     PFAM_domain     complement(10025..11101)
                     /aSDomain="LANC_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05147.15"
                     /description="Lanthionine synthetase C-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_170_0008"
                     /evalue="2.40E-08"
                     /label="ctg3_170"
                     /locus_tag="ctg3_170"
                     /protein_end="380"
                     /protein_start="21"
                     /score="33.0"
                     /tool="antismash"
                     /translation="TSFSLSEGYLGVSVFKYLYAVHTGRKRYLDEAREAFDHACDMIDG
                     DPRKAYPQDFTDLGSVAQYLCQAGVLDIDPNVFLSDVDSILLSKMRAELSAGNIGSLTS
                     GALGYGLYFLQRSYYNRERAQPVVEELVLGIIRSAVRTDGTCHWNAGLDHDEAGSGLFF
                     PQGEAAILLILSRVVEMGLFPATHLEALTQEAIAYIENRHLEQKALSETDKNYGVYLNR
                     QASRYEDISLGYTLLRTGTAFKNAEWSKEGRAILKNCASRHLIDPTGVQNAGILSGATG
                     LALLFDRAAHLTNDVAMEHAANFWYTQILRFDLNADGYAGYKVLENPWSPQSNIAFSEG
                     IIGIGCGLIKSLNPGKVDF"
     CDS             11463..14624
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     714.6; E-value: 2.9e-216)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_171"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7e-166, bitscore:
                     548.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.3e-60, bitscore:
                     200.0, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-09,
                     bitscore: 34.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILSQGFFVLRRPRLPLDVLYEFNARVNNRAELFEKELIRFFSQ
                     PAMLEAIYLASPELYDSFTGLVEGRVKTGTEKLLKTLYKYLVRMTSRSTPYGLFAGCAV
                     GTPGPETRIEFDPTDPEYTHARLDMNYVAGMADALLEKPGIRAALQFSVNTSLYRIGDT
                     YRYVESTWQNEKRSYVLASVDSNEYLDGIIARARTGATIGELARRITGPEISREEALQY
                     IDALIDAQILVSELAATVTGDEFFQVLKAKLSGMDAAAEEVAQMGQVADLLAPGNGGVA
                     KYGEVGELVNRHFVTTGSKDLIQADLFYNTRSCTIGERAIGTLLKEYADIQLLGYQNPM
                     REMDQFKKRFLERYEQREMPLLEVLDSESGIGYGDVAAGRADNLPLLDDLHLPDHGHTP
                     APGLSPLARFREKLCGQAARDHSTAVRLTDAMLQELRETAQPARIPDSFYLFGNLVAGS
                     QQAVDEGDFKFVLNAMGGPSGLKLLGRFCHGNPQLAGRVRKAVAEEENCREDGIFAEIA
                     HLPEARVGNVLMRPHFRQYEIPYLSGSSLPEENRIMPDDLMVSVSAAGEVILRSKRLNK
                     RIFPRLTNAHNFTGGLPVYRFLCELTYQENYRYAGWHWDHLAANTFLPRVEYKHWILSR
                     ATWNLDKALFSKHSLKDIFAADEWLAIRKAYQIPRFVQLRQGDSELLIDGDSDFSVGIL
                     CETLRKYGQITLTEFLESRVLGEPGQHYLNEILIPFLHTQAPAPAKRDTPAASVHAGSA
                     RRNFITGSEWLYVKIYAGTKTVDRLLTTVVKPLADRLVADGTIEKWFFVRYEDPDYHIR
                     LRFYHGSNPSFWHRVLAELNAVMDPLITDGIVHKIQTDTYKRELERYACGSYEEVESVF
                     FADSDATAGFLSLISGDEGERYRWQIGLRAVDMLLNDLGFTLESKKDLMDRLQANFFQE
                     FDGNTQLNIQLNDKYRAQTGTIERFLDPRYDGVNEIEEAIVLFGIRSERIRESMKIIGP
                     TMGVSFLSFASSLVHMFLNRLFVSQQREHELVIYHYLKKYYGSRLARRKNVAKDVIQEG
                     FLVIN"
     PFAM_domain     11595..13544
                     /aSDomain="Lant_dehydr_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04738.15"
                     /description="Lantibiotic dehydratase, N terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_171_0009"
                     /evalue="5.00E-158"
                     /label="ctg3_171"
                     /locus_tag="ctg3_171"
                     /protein_end="694"
                     /protein_start="44"
                     /score="527.1"
                     /tool="antismash"
                     /translation="QPAMLEAIYLASPELYDSFTGLVEGRVKTGTEKLLKTLYKYLVRM
                     TSRSTPYGLFAGCAVGTPGPETRIEFDPTDPEYTHARLDMNYVAGMADALLEKPGIRAA
                     LQFSVNTSLYRIGDTYRYVESTWQNEKRSYVLASVDSNEYLDGIIARARTGATIGELAR
                     RITGPEISREEALQYIDALIDAQILVSELAATVTGDEFFQVLKAKLSGMDAAAEEVAQM
                     GQVADLLAPGNGGVAKYGEVGELVNRHFVTTGSKDLIQADLFYNTRSCTIGERAIGTLL
                     KEYADIQLLGYQNPMREMDQFKKRFLERYEQREMPLLEVLDSESGIGYGDVAAGRADNL
                     PLLDDLHLPDHGHTPAPGLSPLARFREKLCGQAARDHSTAVRLTDAMLQELRETAQPAR
                     IPDSFYLFGNLVAGSQQAVDEGDFKFVLNAMGGPSGLKLLGRFCHGNPQLAGRVRKAVA
                     EEENCREDGIFAEIAHLPEARVGNVLMRPHFRQYEIPYLSGSSLPEENRIMPDDLMVSV
                     SAAGEVILRSKRLNKRIFPRLTNAHNFTGGLPVYRFLCELTYQENYRYAGWHWDHLAAN
                     TFLPRVEYKHWILSRATWNLDKALFSKHSLKDIFAADEWLAIRKAYQIPRFVQLRQGDS
                     ELLIDGDSDFSVGIL"
     aSDomain        13749..14552
                     /aSDomain="TIGR03891"
                     /aSTool="tigrfam"
                     /description="thiopep_ocin: thiopeptide-type bacteriocin
                     biosynthesis domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_171_0003"
                     /evalue="2.40E-57"
                     /identifier="TIGR03891"
                     /label="ctg3_171"
                     /locus_tag="ctg3_171"
                     /protein_end="1030"
                     /protein_start="762"
                     /score="192.8"
                     /tool="antismash"
                     /translation="WLYVKIYAGTKTVDRLLTTVVKPLADRLVADGTIEKWFFVRYEDP
                     DYHIRLRFYHGSNPSFWHRVLAELNAVMDPLITDGIVHKIQTDTYKRELERYACGSYEE
                     VESVFFADSDATAGFLSLISGDEGERYRWQIGLRAVDMLLNDLGFTLESKKDLMDRLQA
                     NFFQEFDGNTQLNIQLNDKYRAQTGTIERFLDPRYDGVNEIEEAIVLFGIRSERIRESM
                     KIIGPTMGVSFLSFASSLVHMFLNRLFVSQQREHELVIYHYLKKYY"
     PFAM_domain     13749..14552
                     /aSDomain="Lant_dehydr_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14028.8"
                     /description="Lantibiotic biosynthesis dehydratase C-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_171_0010"
                     /evalue="4.00E-61"
                     /label="ctg3_171"
                     /locus_tag="ctg3_171"
                     /protein_end="1030"
                     /protein_start="762"
                     /score="207.4"
                     /tool="antismash"
                     /translation="WLYVKIYAGTKTVDRLLTTVVKPLADRLVADGTIEKWFFVRYEDP
                     DYHIRLRFYHGSNPSFWHRVLAELNAVMDPLITDGIVHKIQTDTYKRELERYACGSYEE
                     VESVFFADSDATAGFLSLISGDEGERYRWQIGLRAVDMLLNDLGFTLESKKDLMDRLQA
                     NFFQEFDGNTQLNIQLNDKYRAQTGTIERFLDPRYDGVNEIEEAIVLFGIRSERIRESM
                     KIIGPTMGVSFLSFASSLVHMFLNRLFVSQQREHELVIYHYLKKYY"
     CDS             14748..15560
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 55.4; E-value:
                     8.1e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_172"
                     /transl_table=11
                     /translation="MTGKISCLIVDDEEPAHEVLKFLIAKLSWLVYAGSCYNVVEALEM
                     IPEVKPDIIFLDVNMPELSGLDLLSIVEAPDSHVIMTTAHAQYAVDGFSFDVTSFLLKP
                     IGFDRFLKAVTKVRKLMGNSQPAIDKPRHLAEEVHGGEAPRGNVPAFASEPPAEQRPEP
                     AHEEYMWIRADRKMYCVWFKDIYFIEGLKDYVKVYYSNGVLVTLASMATMMTRLPAPPF
                     VRTHRSYIVNRNMIRMIEGNMVTMLNGMKVSIAVSPTRDEVFRQLTEK"
     PFAM_domain     14769..15089
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_172_0011"
                     /evalue="2.10E-18"
                     /label="ctg3_172"
                     /locus_tag="ctg3_172"
                     /protein_end="114"
                     /protein_start="7"
                     /score="66.6"
                     /tool="antismash"
                     /translation="LIVDDEEPAHEVLKFLIAKLSWLVYAGSCYNVVEALEMIPEVKPD
                     IIFLDVNMPELSGLDLLSIVEAPDSHVIMTTAHAQYAVDGFSFDVTSFLLKPIGFDRFL
                     KAV"
     PFAM_domain     15273..15545
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_172_0012"
                     /evalue="2.20E-16"
                     /label="ctg3_172"
                     /locus_tag="ctg3_172"
                     /protein_end="266"
                     /protein_start="175"
                     /score="60.0"
                     /tool="antismash"
                     /translation="KMYCVWFKDIYFIEGLKDYVKVYYSNGVLVTLASMATMMTRLPAP
                     PFVRTHRSYIVNRNMIRMIEGNMVTMLNGMKVSIAVSPTRDEVFRQ"
     CDS             15570..16712
                     /locus_tag="ctg3_173"
                     /transl_table=11
                     /translation="VENTIVKKRSLIEKLLFPRTQGLRVAYHILFWTCFILLHYAYALP
                     VIGRKSADATVTLANFSYFLKIIPEYYICVGIYNVLGKYVRGILLAFIVVIAALITNHV
                     FSIFMFIGVDKLAGLENMTERFQMFSKMYLQPFDFRDIRSWLVFTNDLSEIQFFMVPAT
                     LKMAKYAANETIARQKLQSDALAMELKALKSQINPHFVFNVLNAAYAKILPISEDAAEH
                     LQKIAEILRFSLYEMDDEFIGLEKELSYMNLYIELESIRSNRRCKVNVSKYGQIAETHR
                     IPTLSLITLVENAFKHGVHASRKESYVNILIDVSSGSLEFTIANSKPENPVLRAKEGRS
                     GGIGLVNLEKRLEIYYPGRYEFEKTETAAEFTVSVTFPLE"
     PFAM_domain     16128..16361
                     /aSDomain="His_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06580.15"
                     /description="Histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_173_0013"
                     /evalue="2.30E-19"
                     /label="ctg3_173"
                     /locus_tag="ctg3_173"
                     /protein_end="264"
                     /protein_start="186"
                     /score="69.6"
                     /tool="antismash"
                     /translation="MELKALKSQINPHFVFNVLNAAYAKILPISEDAAEHLQKIAEILR
                     FSLYEMDDEFIGLEKELSYMNLYIELESIRSNR"
     CDS             complement(17019..19145)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 91.3; E-value: 1.3e-27)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_174"
                     /transl_table=11
                     /translation="MKRTLPFIFGLFAALQAFAQPLPDLSKYKTTTAKLERLAKIGDSL
                     ILAEKHVALHDVALYAIKLTPANDAKRLALFHYQLGFALETTSKSDSCFRIYEKSLDYA
                     KKARDTRQTVQSLDRLLFLYNNVAGFKAKSEAALKEALAIVDTLRDPMDKVELYSSIQN
                     YYSIRGEYEKQVRYLLESIELKKKLIAQGKVKDREYVVSDLMNLAEMYFELEQADNGLR
                     YAKEARSYMVNNTVYRHHYYKDMTDAYLLLRQPAMARTYYDSLSAMLTPDDIQPTRRHN
                     KIAADLGFTDYYLTRNKPDSAAIYIQRAVALAPQWAPDFLMSQVRYMEGSVYYAQKKYE
                     KALPLLTASEPLIEEFGAQMYVALLQSIARCYAAAGQWQNAYAYYDKYAPLRDSLYRES
                     AKKSIADAEARYQNKEKQAEIQIKNLQIDEAQKQRLWLISGLAFVTLSLVLLGVIYRNK
                     RRTATLLDDKNRQLGKLIEDLEEANRTKAKLFGIISHDLRSPISQVYQFLKLQQLNPDR
                     LNHIQKEQLSEKIQTATGSLLETMENLLLWSKTQMNQFQPSIEHVAIAEVTAQCLSLLH
                     LNIEAKQLQVIHDIPGEAAADTDPYYLQTILRNLLQNAIKAAEEQSTLTLAWDEAARRL
                     TIENTGPAFSQAQYERVLAQTDLQKGLSGLGLRLVDELSAKSGLTVRFENPEEGITRTV
                     INVNATTGGSGNGR"
     PFAM_domain     complement(17055..17351)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_174_0014"
                     /evalue="1.00E-08"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="697"
                     /protein_start="598"
                     /score="35.7"
                     /tool="antismash"
                     /translation="DPYYLQTILRNLLQNAIKAAEEQSTLTLAWDEAARRLTIENTGPA
                     FSQAQYERVLAQTDLQKGLSGLGLRLVDELSAKSGLTVRFENPEEGITRTVINV"
     CDS             complement(19149..19868)
                     /locus_tag="ctg3_175"
                     /transl_table=11
                     /translation="MTPPPSRIRFIAIDDNPLDLLFLEEMVSAYPFLENCGTFTNPLEG
                     YEAQQYIRPDLVFLDIEMPAFTGIELLRKFREEVPMAVFITSHPDFALEGFELSALDYV
                     LKPIMENRFAATVARIRDFWEMRQKSHAYEVLFEQDTLTIKEGHNQVKLAQRDIIYLEA
                     MQDYTKIVTPGKNYMTLSTLSCFMEQLPSDRFLRVHRSYAVSLGQIRELRHSELVCDRA
                     IIPIGKTYRSALSKLKL"
     PFAM_domain     complement(19161..19418)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_175_0016"
                     /evalue="8.60E-17"
                     /label="ctg3_175"
                     /locus_tag="ctg3_175"
                     /protein_end="236"
                     /protein_start="150"
                     /score="61.3"
                     /tool="antismash"
                     /translation="VKLAQRDIIYLEAMQDYTKIVTPGKNYMTLSTLSCFMEQLPSDRF
                     LRVHRSYAVSLGQIRELRHSELVCDRAIIPIGKTYRSALSK"
     PFAM_domain     complement(19521..19838)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_175_0015"
                     /evalue="1.20E-13"
                     /label="ctg3_175"
                     /locus_tag="ctg3_175"
                     /protein_end="116"
                     /protein_start="10"
                     /score="51.3"
                     /tool="antismash"
                     /translation="IAIDDNPLDLLFLEEMVSAYPFLENCGTFTNPLEGYEAQQYIRPD
                     LVFLDIEMPAFTGIELLRKFREEVPMAVFITSHPDFALEGFELSALDYVLKPIMENRFA
                     AT"
     CDS             complement(20003..20434)
                     /locus_tag="ctg3_176"
                     /transl_table=11
                     /translation="MKKLIYLISIALLAACQPKQVEPANIGLVWKAQSVKENGTLVYTA
                     GNPASTRPGYARLRLDLTSKEQVTFMDIDGRKLTGKWSLSPDNGRLILENLTPPPSESA
                     GNIEFYLTEPPAAGRLLLKRTNESKKTGNTVNEYELVPE"
     CDS             complement(20466..22199)
                     /locus_tag="ctg3_177"
                     /transl_table=11
                     /translation="MNNRILSPITSTLLCLTAMLAFSTTGHAQRAMLRATAVSYQQVDL
                     SWDRLPGTAELYEIERKEDGPGQNFANIARNVPRGTFAYQDKTVQENRTYIYRVKAYCE
                     KSCGGEFNEARVTTPFAPAATPGNLEVFYISGRGVAITWQGNNSDNARFILERSDNGGG
                     FGTIATVPYARSLSYNDNNVSPGNRYCYRVKAVNAGGESGYSNEGCVNLAIPRPGAPAN
                     LSAKVISSGQVDLKWQDNADNEAGFDVERSDNGTQFSKIGETNANAADFTDSGVQPNRK
                     YWYRVVARNGGGFSDYSNVVEAVTPDIAPNTPRAGSAVAVSYQQINLSWGDVSDNETGF
                     EIESSTNGTQFSKIASTLSNIQNLEIKDLKQLTTYYFRVRAVNAIGPSGYSETMSATTP
                     RAPVPDKPTGLTATPMSFDLIQLKWNALSANAETVVIERSQQPNAGFAKIGSQAAANIQ
                     FPDREILDIHDYYYRVKAVNSNGESPYSDVAKVPAGAIITGVEPVAPEGLVYTHNNRLH
                     IALVRPASGKLHLYDARGVLVRSWPLSQQMQIDLNAWLPGIYVAVLDGEKILVKQKVFI
                     R"
     PFAM_domain     complement(21030..21263)
                     /aSDomain="fn3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00041.23"
                     /description="Fibronectin type III domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_177_0017"
                     /evalue="7.10E-06"
                     /label="ctg3_177"
                     /locus_tag="ctg3_177"
                     /protein_end="390"
                     /protein_start="312"
                     /score="26.4"
                     /tool="antismash"
                     /translation="PRAGSAVAVSYQQINLSWGDVSDNETGFEIESSTNGTQFSKIAST
                     LSNIQNLEIKDLKQLTTYYFRVRAVNAIGPSGY"
     CDS             complement(22225..24213)
                     /locus_tag="ctg3_178"
                     /transl_table=11
                     /translation="MKTIIRILTLFCLGTAALQAQKPQAIGGPYGVFIQIDKLLHGPQY
                     VIERLETGKNKPEWQPVCTTGKGPANAAELTARLTVLAAKNPLYQLPNDSLTTLLFDRY
                     RNVAHADSLGGYGSNPQYLEALGLGFLDTGVQQGLRYDYRLRALGAREGVYHNPGTVSV
                     PGAKLATTARSVSRHTDGRTVSIQYLIKKPNPYIAGARVLRAAFGQTGFEECGAEWGFR
                     KGERDSLFLVVTDPNVRRKMLYSYVVYLQDFVGNESAASDTLTLANLRAQDEIPVIHRI
                     STRSVESDNAITVSWELSSVKDLRAVEIWRSEDFDTGFKRVGVAAATDTAYTDHAVEPV
                     QGYYYQVRLNGTYESSPASVKVSGMLKANRPALLAPAHFQLTETQDSLTFRWEAADFDT
                     HGYYIYFAAGQTDTLQQFSDMIPAHAALKYQIPVQKLAIGVAYRWAVVAVNTSYNQGPM
                     SNELYSEPRFPTRLATPLNPELIDQPGNAWLVWENMKAIDPYTLGYIIERKAENEKAFK
                     EIYRQHAEDQARNHYADSTVKQGVHYSYRIRAYGMGGRLSAFSTEIGYYQPHDAVLPVH
                     GLNVATTNRGVLVSWDAPLAKPDKYLVYRYTEKTEKPRLVSAPLGTQTGYIDRDAVAGV
                     GYYYHVVAVGTDNRESAPTDPVKVDWK"
ORIGIN
        1 cattaccacc ggcgcgcaca cgatcgacca gctgcgtacg gtatccccgg aatacatcat
       61 ccacagcctt accgaactct ggccgatcgt ggcgtcgccg ctcgcgccgg tgaaccagca
      121 catttgagga gggttcactt aattaatcca cagcgtgccg ttttttgtga tcagcctgga
      181 aaggctgccc gattcgacga gtttctgcaa aaaggcctcg ctatcctcgc ggggcgtttg
      241 cgacagctcg gcgaattcgc gtgtcgtgag tgtacggtat cgggtaaata acttttgcca
      301 accagtgtcg atcgggctct tcacagccga aggcagttgc ctgcgcaatg cggcttcgta
      361 tacttcgtag ggtttcgtgc cgtacacctt ttcgagcccg ccgttccgat ccgcgaaaaa
      421 gagggtagga aagccccgca cgcccagctg cgcgcccagg tcgaggtctt ccttgaaaag
      481 gcttttggca tggccatgat aatccgcttc gaactgctgc aaatccagtc ccacattacc
      541 ggcagcggtg gcgaggtgtt tccactgggt aatgttctgt tttcgcagga ataccatttc
      601 gcggatctcg cgcaggaacc gcaccgcttt ggccgcatcc tgcatttgtg ccgccttgaa
      661 tgcgatggac ggcggatagg acgaatgtag cgggtcttcg agccacacgt cgccgtcgat
      721 gggcatgtcg tagtagtggc tcacctcgtc ccagtgatgg gctacgtcgg aaggcttgct
      781 gatgccgccg ctgttgtagc tccaatcggg caggaggccg cccatgcggt attcgatgtc
      841 gaagtagcgg ccgtattcca ttttgagttt gcgcaattgc ggctcgatgc cccagcacga
      901 cgagcagatc ggatcggtga aataaatgat tttcaataca ttatgcgcgg tggcggcggt
      961 ggtagcggcc gtatcggcgt tgtttccggg catttcgcaa atgccggact ctatgtcgca
     1021 taaaagcggg ttgctctgtt ctgtattcat gtcaaatcgt acgttctgcc cgcattgggc
     1081 cgtttcatac cgcaaatttc ccccggtttt cgacaggagt caattagtca gaaattcttg
     1141 actacccgct tcggatcaat gggtgctctc aattcattga taatcaacta aaaagcgatt
     1201 gaataaattt taaggttgga taacgggacg aaaccgccta acttttgagc ggatagcgtc
     1261 cattcaatgg ctatccgttt gatatggaaa acacggaaga aggccagggc caatgcccgg
     1321 cggagacatt gctgaaacag ctcgcgggca aatggaaacc gcaaatattc aggatcgcat
     1381 tggcagggcc ggtccggttc aatgcgttgc tgcgtcagct ggacgggtcg agcaagcagg
     1441 ccattgccag cgcattgaag gagatggaag aacagcagct gattgaaaaa caggtcatta
     1501 aactgaaacc gctgcatatc gaatacattt tgtcggaacg cggccggtcg ctgatcccga
     1561 ttttcaggca gctggaacac ctggcgtgaa acgccattaa cctcttttcg ggcacgctcg
     1621 ctgcccctga tttttacgcc cgatcacccc ctcatttccc gcgcctcccc aggggcgtgt
     1681 aaacacctgt tttgcctaaa cgggtgttta cacgcattcg tgaagaacta tttcgatcca
     1741 cctttgtaga gcaaaagctt ttgtacggtg gagcccagtc accacctcaa aaaacggact
     1801 tgcctgtaag agtattggtt acaggggcgg ttcccgaacg tcatttcgcg ggttacttac
     1861 attttcaacg atgagcgatt tcctagactt acaaaatggc tggtacaatg gtctgatcca
     1921 gggattggga caaagccagg attcttttca gatcattcag cctgcgccgc cgattgccag
     1981 cggtaccgcc gctaacccga ctttctgggc ttactacaac aacatccctc cccaatcatt
     2041 gactgcccag ttcgtcgcca gtggtggtaa ccagttttac agcaattaca gaggcttgct
     2101 ttcggcactg gagccgtcac gcaatatcaa tgtgaaagaa gacatcggtg aggcgaactt
     2161 cctcgcatgg caggcctacg tgcaaacgca gcctacgccg agcatgaacc agatcccgac
     2221 gatgttcaga aactgggcga tgttcaatgc cccggaggta gcgaacatcg gttcatccga
     2281 ctacgctgcc atcctgctcg accccattgc taccgcgcag aacgagctga cattagtgta
     2341 caccacgcct gccggtctgc cgatcaattt cgactggcag ctgaactacg ccgatatggt
     2401 gaaccagctg gccagcgcgc cttcccgttc gttctcgttc gatagcagca cgatgaacaa
     2461 gaatgtaagt ggctcatggg caggtagttc caaatcgggc ttcttcggct tgtggggcgg
     2521 cagcagctct acttcttcgc tgagcgagca atttgcttcc agccgtatcc aggtgagcgc
     2581 gagcttcgag cacattcttg tattgcccaa cacgccgggc gcgtggtact attcttccgc
     2641 catgggactc gcatttgcca acaagacagg cagcccctgg agagataagg cggccattaa
     2701 ctggaacaat acgttcgggc cggatggtaa catgcagtat ttctccgcaa acgtcatcgt
     2761 ggcgtccggt atgtccatca ccgttacgtc ggatgcgtcg tattcgtcgc tggatcagca
     2821 gacgatcact tccagcgggt cgtccggctt ctggccgttc tattccggtg acagcggcag
     2881 ctcgtcgacc aaccgtgtga cgttcaacca ggacggccac atgaccatca ctaccagcag
     2941 cattccgggc gtaccggtgg tagtgggcgt gaacgtactg tcggccggcg aatttgtggg
     3001 ccactcttca agcctgggcg tttcgctctt cgaatcggcc aaagctttcg cggcagaaag
     3061 cctcgctacc gtttaagttt tcgcaggaca ggccgggatg ctcgaaagag ccccggcctt
     3121 cttttttgat tttaaccagg aattactatg atggcaacag atacctccac cgacgcggtc
     3181 accgccctga cggacgcctg gtacaatcag ctggcggcca gtctcagcct gtcggtccgc
     3241 aatttccagc tgctgcaacc gccggccgtg ccgacgggcg atcagagcct ttgggacagt
     3301 ttcaacgtgg ttccgccggt gacgctcaaa tacaatcgct gggtgtacca gcagcctgca
     3361 tttttcaaac agtatgcggc attggtgaac agcctgtcgt ttcctgagag cgcatttgtg
     3421 gaagatatcg gggccgatac ctacgtgcaa tggacggcct atctcaaaac cgtgagcccg
     3481 ccgcctgcgc ccaacgagct gcctggcgtg tggttccaat gggcgatgct gcatgcgccg
     3541 tcggtcgcga atatcgggcg ctccgacctg gccacgcagc tgctcatcgg tggtgcgcag
     3601 gctgcattgg agccctatga aggccctgat gccaaacagg ccgattactc gccttctttc
     3661 ggggatctaa aaaacatcct gaaactatct tccggagcga gcttctcgtt cgattcgtcc
     3721 acggccgatc ccgacgtgtc cggctcatgg gtacccggcg acgaccccaa ttatttcggc
     3781 gtgtggacgg gcagttcgac cgcattccgc atcagccgga agttcgcgct gagcaagatc
     3841 accgtcaccg ccgcattcga ccatttcggc gtcgttcccg ttacgcccgg cccctggtac
     3901 aattccagca tgctgcacct tgcctgggtg tcgggggcta gtgttcctcc ctgggtcagc
     3961 gagtccgact gggataggta tttcggcgca tccggcaagc ttacccacgc aatcggctcc
     4021 gtactggcgg ccgacggcat tacacttacc ctccactccg atgccaattt cagtcccgaa
     4081 gagcaggctg tcatccgcgt gctcgcgctg atgggcgact ggcctgtgta ttgcccggtc
     4141 caattgtcgg cgatcaccaa taccgtcacc agcgcgccgg gctcgctcac gatccgtttc
     4201 catgccgcgc cgggcaatcc cgtgatactg ggctacaacg tgttcgatat ccgaagttac
     4261 acgggcgctt aggaacgcta tgccgccgcc gccggctgca tggtggtgct gatggcgatg
     4321 cggttccagg tattgatggt cgcgatggcc atgatcacct gcgccaggta ttcctcgtca
     4381 agaagtgcgg aggcctgtgc gtacagctcg tcgctcacgc cgccccggtg aatgagcgta
     4441 actgcctcgg tgagtgcgag tatcacgcgc tcttccgggg tgaacagcgc cgtttcccgc
     4501 caggcattca gcagcacgat gcgctggatg ctttcgccgg ctttcagggc gtctttggta
     4561 tgcatatcga tacaaaacgc gcatccgttg atttgcgaag cccggatttt gatcagctcg
     4621 cggtgtgttt tgctgagttt cgaagcgctc agatactgtt cgagaccgta catggccttg
     4681 tatgcctgcg gctgcgtggc cgctacgtct acccttgttt tcatctgttt ttcaaatggt
     4741 tgattgatgg gtcaaaggta gcggggcgtc agccgcattt acttaaactg gtttaagatc
     4801 gctttttgcg gagctcgctc aggtattcgg gcgtgatgtc gaggtaggaa gcgagcagat
     4861 attgcggcac gcgctgcacg aagtcagggt agaggccggc aaactgccgg tacagcgctt
     4921 ccctggacat atcctgctgg tacttcatcc gcagcatcgc cgcgccgtag ccatactggt
     4981 aaagaatgcg gaaataccgc tccatgcgcg ggaaggcgtc gagcatcgca tgataagact
     5041 gccggtcgat ggacagcact tcggccggct ccaccgcctg aatggcaaat ccggtctgct
     5101 gtttcttttc aaatgcaaga aaatcggtga gccaccagct ctcaagggca aactgcgtgg
     5161 tatgctccac gcctttacta tctgcaaaat acatccgcag gcacccgcgc acgacgaaat
     5221 acagcgtggt gcattcccgg tcggcctgct ggacgacctc ctttttggcg acctgccggt
     5281 accggaaaaa atccagtaca ccgcccgttg tgtcggttgg taatccggca atggctttga
     5341 tgtgctcggt aagtgcccgg ccggcgtttt cggggaaatc catatgcacg gttgtttggt
     5401 caaatttact ttttacatcg gcatcggaga atgtttttta tattttccct aaaattccgg
     5461 taaaagtact acggccatgc agaaaaaatt tgatctgaaa tccttcaacc tgtatcaatt
     5521 tctcaaacat cagaacgcgc acaactttca tacgcctttc ttcctggccg ataaagacac
     5581 ctatcgccat gcccacgtca attttccgtt caggacattt gcatacggac tcggtgtgac
     5641 ctattcgggt gatggcgaca cgttcaaaat aggcagtacg gattatacgg tgggggcgca
     5701 ttgcctcacc accatcgggc ctgggctggt gtgccaatgg gcgggtaact acacggccga
     5761 gcacgacacg gtatatttta ccgaagagct gttcagggat attcgcacga atgctttttt
     5821 gcagtcgcta tccttctttt ttcacggcgg caaccacgtg atccggctca cggaggcgca
     5881 gacagccaaa atgcggtcgc ttttcgaggt attgaaagaa ttgaaaaacg acaatgaggc
     5941 cgttcccggc atcgtgtact ccctgctgaa actggccgat tcctttcacg gggctgccca
     6001 tgctgcatcc gatggtaacc gggttaacac aggactcggc aatggtaccg gcagcattga
     6061 atccaatgcg gaccacgctt ccggcgatgc gcctgccccg cccgcaaacc gggcttccag
     6121 ccgtatttcc agcaagcaga aaatcacccg agcgttccgc aagctggtgg cggagcattt
     6181 tcccgagcat aaggaagtgg cacactatgc caccgaactg aatattaccc ccaaatacct
     6241 gagcgaaatc ttgcaggccg agctcggcaa gccggccaag acgttcatcg atgagcacgt
     6301 gctcatggag gccaaaagcc tgctcaaaca gaccaccttt tccgtacagg aaatctgcta
     6361 ctggctgggc ttcgaggacg cttcccactt caccaaatgg ttccggaaac aggccggcgt
     6421 cacgcctacc gagtaccgga aggaataacc gacttttgta ccatttctcc cgaaatccgg
     6481 cctaacacca gggccctgca cggtggtacc tttgtttcga accaatcaaa aacacagacc
     6541 atgaagaacg cagaagcatt tgaagtagcc gtttcccaac aggtattgga cgatctgaaa
     6601 aaccgcctgc aaaacacccg ctggccgggc gaggcagacg gctccggctg ggcattcggg
     6661 acgagtgaag cgtatttgaa agaattgacc caatactggc tccacaccta cgactggcgc
     6721 aagcaggagg aggccttgaa ccggtacccg caatacatcg ccgatgtgaa tggcgtacaa
     6781 gtgcattttc agtatattaa aggcaatggt gcgaatgcga agccgctcct gctcacgcac
     6841 ggatggcccg atagctacta tcgtttccac aagctcatac cgctgctgac ggaaggcgaa
     6901 cagccgttcg accttgtgat cccctccatt ccgggtttcg ggttttctga aaaaacggcg
     6961 ctgtcgagca cggccgtcgc cgacctttgg aaagacctca tgacccaaac gctcggttac
     7021 gagcatttct acgctgccgg cggggatatc gggatgagtg tcaccaaagc gctggcttcc
     7081 aaataccccg gcatcgtggc aggcgtgcat tttacggaca ttggttaccc gatgggccag
     7141 gaagacccgg ctaccatgac cgaggccgag cagcagttcg cgcagtttgt gcagcaatgg
     7201 tggtacagcg agggcgccta tgcgatggtg caggccacga agccccagtc gctcgcctac
     7261 gggctgaacg actcacccgt cgggctggcg gcatggatcg tcagcttcgg caatgcgggc
     7321 gcccatcccg acatactcga aaaagcattc ggcggccggg atgcgctttt gaccaacatc
     7381 atgatttatt gggtcacgca aaccattgcc acctccgcgc ggatatacaa ggtggacgcg
     7441 atggcgcaat ggagcggcga aaagcctttg gagaagagcg atgtaccggc cggtatcgcg
     7501 gtgtttccga gggaggcaca gttcccgaaa gaatgggccg agcgcttcgt ccatgtcgtc
     7561 agcttccgtg caatggacga gggcgggcat ttcgcggcgc tggaagtgcc ggagattttc
     7621 gcggcggaac tgaaaaggtt tttctcggaa cttcattaaa ttggagattt gatgacctaa
     7681 acagccgccg atcccgttcc gatgcattcc atcttacctt ttatgctggc catggtggcc
     7741 gctatcgtat tgctgaatat gtgggccacc aaactgaaag tggcataccc cattctgctg
     7801 gtggtggccg gcctgctggt gagcttcgta ccgggattgc cggtgttgaa aatcaatccc
     7861 gacctgattt ttctcatttt tctcccgccg ctgctgtttg aggccgcctg gtcggtttcg
     7921 ttcaaggaaa tgcggaaatg gtggcgcata atcggcagtt tcgcgttcct ggtggtcttt
     7981 tttacggcat tttcggtggc cattaccacc acgtacctga tccccggctt caccatcgcc
     8041 ctgggcttcc tgctgggcgg catcgtttcg ccacccgacg cggtcagtac cggggcgatt
     8101 atgaagtttg tgaaaatacc caagtcgacc gtcgcgatac tggaaggcga gagcctgctc
     8161 aacgacgctt cgtcgctcat tattttccgg ttcgcattgg cggcggtggc tacggggcac
     8221 tttgtatggc agcaggccgc aaccagcttt ttgtggatgg tcgccggtgg cgcgggcatc
     8281 gggctggcgc tcgcgtgggc gttcgtgcag gcccacagga ggcttcctac cgacgcaccg
     8341 tcggacattg cgctcacgct tattgagcct tatgtgatgt attgggtagc cgaagagctt
     8401 catagctccg gcgtgctcgc ggtggtggcc ggcgggttgt tcatgtcggc ccgccggctg
     8461 tcgtttttga gtagtaccag ccgcattatg ggttacagtg tttgggagag ctttgtattt
     8521 atattaaacg gcgtcgtgtt cctcatcatc gggctcgatc tgcctgaaat cgtcgaaggg
     8581 ctgcggctgg aaggcgtgcc gctgcgtacc gccatcggct acggcgtgct ggtcacgctg
     8641 gtgctgatcc tggcgcggat gatcagttcc tatgccgcga tgatcgccac gctcatcttc
     8701 cggccttctg tggcaccccg tgcccgctcc aaccgggcgc gtttcaaaat gccgctgctg
     8761 cttggctgga ccggcatgcg gggcgtggta tcgctcgctg ccgcattgtc catccccgtg
     8821 gcgctggaca acggagccgc attcccgcag cgcaacctga tcctcttcat tactttcgtc
     8881 gccatcctgc tgactttggt cgtccagggg ctcacgctgc cggctttcat taagcgcggg
     8941 aagctgttcg aggcattcac ggaagattcc gagcaggaag ccatgcagaa gatcaagcgg
     9001 gggctgcggc agcagatcta ccattttttg cagcaccgga aaaacgacgg gctgcatgaa
     9061 gagatggctg tccgcaaaat cctgcaacat tgggaagaaa aggccaaatc atccgacgac
     9121 gaatggatga atgaccaaac caaagctatt ctgctggaaa tgctggaatg ccagcgcacc
     9181 tacctcgccg aactcaataa ggatatctct gtcaatgaag actacattcg ccggcagctc
     9241 taccagatcg acctggaaga agagcgcctt cgtatgattt gaagcgacgg ggcggtggga
     9301 gttttgaatg gaaatttatt gcataaaaga actttgtatt tcaaagttct tttatatttt
     9361 tgcgtaaacc tgtatgcctg ctaaggccgg caggacagca ggtccattct caaaccattt
     9421 caatctattc aagctatgaa gaacgatgta aaaaaactgc tgatcgcggc cgctggcgct
     9481 gtgactgttc cgctgttgct gacggcgctg gcgctttggc aatggaaacc cggcgcgccg
     9541 atgctggcgg tcgtgctgtt gctgggcgcc gttgcgctcg tatacgacct ggtggccaaa
     9601 cggaaactga acagccatgc ctaccggttt gcgttgggca tcgcgatcct gacggtactc
     9661 gcattgctct ggatgaatgt ggccgtgggc ggcattctcg gcgataatcc ggcgaatatg
     9721 atgtatttcg gcgtgctgat cacgggcctg gccggtgccg tcatagcacg cctcgaagcc
     9781 gtaggaatgg ctttcgcatt gtttgcgatg gcatttgcga tagttctcat ccccatcata
     9841 gcgtgggcga tcggtacgcc tgcttttgcc aatggtttcc cggcggtaat gggcctgcat
     9901 gccggttttg cattactttt ttgcggatcg gggacgtttt tcctgcgtgc ggcgcggggg
     9961 cagcgcacga ggcacatgtc caccggcgct tagcgatcgt tcagagcagc cagatcagat
    10021 catgaaaatc caccttcccg gggttcagcg atttgatcag cccgcagccg atgccgataa
    10081 tcccttcgct gaatgcgata ttgctttgcg ggctccacgg gttttcgagg accttgtagc
    10141 ccgcatagcc atcggcattg aggtcgaaac ggaggatttg cgtataccag aagttggcgg
    10201 catgctccat cgcgacgtcg ttcgtcaggt gtgcggcgcg gtcgaacagc agggcgaggc
    10261 ctgtcgcacc cgacaatatc cccgcatttt gtacgcctgt cgggtcgatc aggtggcggc
    10321 ttgcgcagtt tttgagaata gctcttcctt ctttggacca ttcggcgttt ttgaatgccg
    10381 ttccggttct taacagggtg tatcccaggc tgatatcttc atagcgtgaa gcctgccggt
    10441 tcaggtatac cccataattc ttgtccgttt cagagagcgc cttttgttcc agatggcggt
    10501 tctcgatgta ggcaatcgcc tcctgggtaa gcgcttccag gtgcgtggcc gggaacaggc
    10561 ccatttctac gaccctgctc agaatcagca atatcgccgc ctccccctgc gggaaaaata
    10621 gcccggagcc ggcttcgtcg tggtcgaggc cggcattcca atgacaggtg ccgtcggtgc
    10681 ggaccgcgct ccggataatg cccagcacca gttcttccac caccggctgg gcgcgctcgc
    10741 ggttataata gctgcgttgt aaaaagtaca gcccgtagcc cagcgcgccg ctggtgaggc
    10801 tgcctatatt ccccgcgctc agttcggcgc gcattttact taataatatg gagtccacat
    10861 cgctcaggaa cacgttcgga tcgatgtcga gtacccccgc ctggcagagg tattgcgcaa
    10921 cggagcccag atcggtgaag tcctgcgggt aggccttccg cgggtcgccg tcgatcatgt
    10981 cgcaggcgtg gtcgaatgcc tcccgcgcct cgtcgaggta gcgtttgcgg cctgtgtgta
    11041 cggcgtagag gtatttgaaa acggatacgc ccaggtatcc ttccgacagg ctgaaactgg
    11101 tcagctgccg gcggtaaatg ttgatgacct cgtggatttc gtcgattttg gcagcggcaa
    11161 tcatggtcga cagcctcgat attcctggtg atgttgatat cattatcgtg cacaaatttg
    11221 atctgtacac aaatgtgggc aagcgcggca actggcgcac attttttaga ccaattcacg
    11281 ggctatttcg acgaaatgat gcaacggtgc ggcgcacggg cattctggcg gcgggatcgg
    11341 gcttttttcg acggcgggga ttttgtccat gaaagcagat cattggtata aacaatttgg
    11401 cggccggcga agagaatgaa aagtttggac cactttgttt ataatgatta acccgccggc
    11461 ttatgtctat tttatcccaa ggatttttcg ttttgagacg tccccgcctg ccgctggatg
    11521 tcctgtatga gtttaatgca cgggtcaaca accgggccga gctttttgaa aaagagctga
    11581 tccgtttttt ttcccagcct gccatgctgg aagccattta cctggcatca cctgagctat
    11641 acgattcgtt taccggactg gtggagggcc gggtgaagac cggtaccgaa aaactcctca
    11701 aaactttata caaatacctc gtgcggatga cctcccgcag taccccgtac gggctttttg
    11761 ccggctgtgc ggtgggtacg cccggccccg aaacccgcat cgaattcgac ccgaccgacc
    11821 ccgagtatac gcacgcacgc ctcgacatga actatgtggc cggcatggcg gacgcccttt
    11881 tggaaaaacc cggaatccgc gcagcattgc aattttccgt gaataccagc ctttatcgta
    11941 tcggcgatac ctaccgctac gtggagagca catggcagaa cgaaaaacgg tcgtacgtgc
    12001 tggcatcggt ggacagcaac gaatacctcg acggtatcat tgcccgcgcc cgcacgggcg
    12061 cgacgatcgg ggagctggcc cggcgtatca ccggcccgga gatcagcagg gaagaggcat
    12121 tgcaatatat cgacgccctg atcgatgccc agatactggt gtcggagctg gccgctacgg
    12181 tgacgggcga cgagtttttt caggtattga aggcaaaatt gagcggtatg gacgcggcgg
    12241 cggaagaggt ggcacaaatg gggcaggtgg ccgacttgct ggcgcccggc aacggcggcg
    12301 tggcgaaata cggcgaggta ggggaacttg tgaaccggca tttcgtgacg acgggcagca
    12361 aggacctcat ccaggccgac cttttttaca acacgcgctc ctgcacgatc ggcgaacggg
    12421 cgattgggac gcttttgaag gaatatgccg atattcagtt gctgggctac cagaacccga
    12481 tgcgggaaat ggaccagttt aaaaagcggt tcctcgaacg ttacgaacaa cgcgaaatgc
    12541 cgctgctgga agtgctggac agtgaatcgg gcatcgggta tggcgacgtg gccgccggcc
    12601 gggccgataa tctgccgctc ctggacgacc tgcatcttcc tgaccacggg cataccccgg
    12661 cgccggggct ttcgccgctc gccaggttcc gcgagaaact ctgcggacag gccgcgcgcg
    12721 accattccac ggccgtccgg ctgaccgacg ccatgctgca agaactccgc gaaacggcgc
    12781 agcccgcccg gatacccgac agtttttacc tgttcggaaa cctggtggcc ggctcgcagc
    12841 aagccgtcga cgagggcgat ttcaaattcg tactgaatgc catgggcgga ccatcgggtt
    12901 taaagctgct cgggcgcttt tgccacggca acccgcagct ggccgggcgc gtcaggaaag
    12961 ccgtagcgga ggaagaaaac tgccgcgagg acgggatttt cgcggaaatc gcgcatttgc
    13021 ccgaagcccg cgtcggcaat gtgctgatgc gcccgcattt ccggcagtat gaaatcccgt
    13081 acctttccgg ctcctcgctg ccggaggaga accgcattat gccggacgat ctgatggtgt
    13141 ccgtatcggc ggcgggggag gtaatattgc ggtcgaagcg gctgaacaaa cgcattttcc
    13201 cgcgattgac caatgcgcac aatttcacgg gcggcctgcc ggtataccgt ttcctctgcg
    13261 agctgaccta ccaggaaaac taccggtatg cgggctggca ttgggaccat ctggctgcga
    13321 acacattcct gccgcgggtc gagtacaagc attggatact gagccgcgca acctggaacc
    13381 ttgataaggc gttgttttcc aaacattcat tgaaagacat ttttgctgcc gacgaatggc
    13441 tggcgatacg gaaagcctac caaattcccc gtttcgtgca gctgcgccag ggcgacagcg
    13501 agctgctgat cgacggcgat tccgactttt ccgtgggcat actctgcgaa acgctccgca
    13561 aatacggcca gatcacgctc acggaattcc tcgaaagccg cgtcttaggc gagcccggcc
    13621 agcattacct gaacgaaatc cttattcctt tcctgcatac gcaggctcct gcgccggcga
    13681 agcgggacac gcctgcggca agtgtgcacg caggcagcgc gaggcgcaac ttcattaccg
    13741 gcagcgaatg gctgtatgtc aagatttacg ccggtaccaa aacggtggac cgcctcctta
    13801 ccaccgtcgt gaagccgctt gccgaccggc tggtagcgga cgggacgatc gaaaagtggt
    13861 tttttgtccg ctatgaagac cctgactacc atatacgcct gcggttttac cacggcagca
    13921 acccgtcgtt ctggcaccgg gtgctggccg aactcaatgc ggtgatggac ccgctgatta
    13981 ccgacgggat cgtccacaaa atacagaccg atacctacaa gcgcgaactg gaacgttacg
    14041 cctgcgggag ctacgaggaa gtggaatccg tgtttttcgc cgacagcgac gccacggcgg
    14101 ggtttctgag cctgatttcg ggcgacgaag gcgagcggta ccgctggcag atcgggctgc
    14161 gggccgtgga catgctgctg aacgacctcg gttttaccct cgaatccaaa aaggacctga
    14221 tggaccgcct gcaagccaac tttttccagg agttcgacgg taacacgcag ctaaacattc
    14281 agttgaacga taaataccgg gcgcagacag gcacgatcga acgttttcta gatccgcgtt
    14341 acgacggggt gaatgaaatt gaagaggcca tcgtgctgtt cgggatacgt tcggaacgca
    14401 tccgggagtc gatgaaaatc atcgggccga cgatgggtgt atcgttcctg agcttcgcga
    14461 gcagcctcgt ccacatgttc ctgaaccgcc tgttcgtatc acagcagcgg gagcacgaac
    14521 tggttattta tcactatctc aaaaaatact atggctcccg cctggcgcgc aggaaaaatg
    14581 ttgcgaagga tgtgatccag gaggggtttt tagtaataaa ttaaacgata atgcgcatat
    14641 ttgttgcgaa aagtgtaacc gcatttggtt tttgttgacg tttttacggt taggtacctt
    14701 ccatagacat taacgatcat caatcacaat tcggactcgg tgcaaatatg acaggaaaaa
    14761 tcagttgtct catcgtggac gatgaggagc cggctcatga agtccttaaa tttctgattg
    14821 caaagcttag ctggctcgtc tatgcaggca gttgttacaa tgtcgtggag gcattggaaa
    14881 tgattcccga agtaaaaccc gacattattt ttctcgatgt aaatatgccg gaactttcgg
    14941 ggctcgacct gctcagcatc gtcgaagcgc cggattcgca tgtgatcatg accaccgccc
    15001 acgcacagta cgcggtggac ggtttttcat ttgatgtcac gtcatttctc ctcaaaccca
    15061 tcggtttcga ccgtttcctg aaagcggtga cgaaggtgcg aaagctgatg ggcaacagcc
    15121 agccggccat cgacaaaccc cggcacctgg cggaagaggt gcatggcggg gaggcaccgc
    15181 gcggaaatgt ccctgcattc gcttccgagc cacccgccga gcagcgtccc gagcccgcgc
    15241 acgaggagta tatgtggatt cgtgccgacc ggaaaatgta ttgtgtctgg ttcaaggaca
    15301 tctattttat cgaaggattg aaagactacg taaaagtgta ttattccaac ggggtgctgg
    15361 tgacgctcgc ctccatggcc acgatgatga cgcggctgcc ggccccgcct tttgtgcgga
    15421 cgcaccgttc ctatattgtc aaccgtaaca tgatcagaat gatcgaagga aacatggtca
    15481 ccatgctgaa cggtatgaaa gtatccattg ccgtttcgcc cacgcgcgac gaggttttca
    15541 ggcagttgac agaaaaatag cattcaggcg tggagaatac tatcgtaaaa aagcggtcgc
    15601 tgatcgaaaa gctcctcttc ccgcgcacgc aggggctgcg ggtggcttat catattctgt
    15661 tttggacctg ttttatatta ttgcattacg cttatgcgtt gccggtaata ggacgaaaga
    15721 gcgctgatgc taccgtaacg ctcgccaact tttcttactt tttaaaaata atacccgagt
    15781 actatatctg cgttggtatt tacaatgtat tgggaaagta tgttcgcgga atattgctgg
    15841 cgttcattgt cgttatcgca gcactgatca cgaaccatgt cttctccata tttatgttca
    15901 ttggggtgga caaattagcg ggcctcgaaa atatgaccga acggttccag atgttttcga
    15961 aaatgtatct acaacctttt gattttcggg acattcggtc gtggcttgtc tttaccaacg
    16021 acctttccga aattcagttt tttatggtgc ctgcaacgct gaaaatggca aaatatgcag
    16081 cgaacgagac cattgcccgt caaaagctgc aaagtgacgc attagctatg gagctgaaag
    16141 cgttgaaatc gcagatcaac ccgcatttcg tatttaacgt attgaatgcg gcttatgcta
    16201 aaattttacc aatttcagag gacgctgccg agcaccttca aaaaatcgcc gagattctac
    16261 ggttttcgct ttatgagatg gacgatgaat ttatcggact tgaaaaagag ctttcgtaca
    16321 tgaatctata catcgagttg gaatcgatac gtagcaaccg ccgctgcaag gttaatgtaa
    16381 gcaagtacgg gcagatcgca gaaacgcatc gaattccaac attatcgttg attacgctgg
    16441 ttgaaaatgc attcaaacac ggcgttcacg caagccgcaa ggaatcctat gtgaatattc
    16501 tgatcgacgt ttcgtccggc tcgctggaat ttaccatcgc caacagtaag ccggaaaatc
    16561 cagtcctgcg tgcaaaggaa ggccggagtg gtggaattgg tctggttaac ctggaaaaac
    16621 gattggagat ttactatcct ggtcgctatg aattcgagaa aacggaaact gctgccgagt
    16681 tcacagtttc ggtgacattt cccctggaat agcagtttcg aagcaatact tcatttggtc
    16741 gaggaagggc cgagcttcgt ataaaaagat tctacagccg ctttttgaag gattaatttg
    16801 tggtgttaat caaccctaat tatacaatga aaaagcaaac aaccatcccc gctaaacttc
    16861 aactcgtaaa atcaactgtg gcacgcctga atggattttc atccatccgc ggcaacagaa
    16921 ttcacattca ggacgagacg accgcgagca gcatgctatg tagaacagta ctgatctgac
    16981 atcgcgaccc gaagcggaaa agtgcccgcc ccacgccact accggccatt ccctgaaccg
    17041 ccggtagtgg cgtttacatt tattactgtc ctggtgatcc cttcttccgg gttctcgaac
    17101 cgaaccgtca ggccggattt ggccgagagc tcgtccacga ggcgcaagcc tagtcccgag
    17161 aggccttttt gcaggtccgt ttgtgcgagt acccgctcgt attgcgcctg actgaatgcc
    17221 gggcccgtgt tttcgatcgt caggcggcgg gcggcttcgt cccaggccag ggtgagcgta
    17281 ctttgctctt cggcggcttt gatggcattt tgcagcaggt tgcgcaggat tgtctgcagg
    17341 tagtaggggt ccgtgtcggc ggcggcttcc ccgggaatgt cgtggattac ctgcagctgt
    17401 ttggcttcga tattcagatg cagcaggctc aggcattggg ccgtcacctc ggcgatcgcc
    17461 acgtgttcga tgctgggctg gaactggttc atctgcgttt tcgaccagag gagcaggttc
    17521 tccatcgttt cgagcaacga gccggtggcc gtttggattt tttcgctgag ctgctctttc
    17581 tggatgtggt tcaaccggtc gggattgagc tgttgcagtt tcaggaactg gtacacctgg
    17641 ctgataggcg agcggaggtc gtggctgata atgccgaaaa gcttggcctt ggtgcggttg
    17701 gcttcttcca gatcctcgat cagcttcccg agctggcggt ttttatcgtc gagcagggtg
    17761 gccgtgcggc gtttgttccg gtaaataacg cccagcagca cgagcgacag cgtcacgaat
    17821 gccagtccgg agatcagcca gaggcgctgt ttctgcgctt catcgatttg caggttcttg
    17881 atctgtattt cagcctgctt ttccttgttc tggtagcgcg cctcggcgtc ggcaatgctc
    17941 tttttggccg attcccggta gagcgagtcg cggagcggcg catatttgtc gtaataggcg
    18001 taagcattct gccactggcc tgccgccgca tagcagcgcg cgatcgattg cagcagggcc
    18061 acgtacattt gcgcgccgaa ttcctcgatc agcggttccg aggcggtcag cagcggcagt
    18121 gccttttcgt atttcttttg cgcataatac acgctgcctt ccatgtaccg cacctgtgac
    18181 atcaggaaat ccggcgccca ttgcggggcg agtgccacag cgcgctgaat gtaaatggcc
    18241 gcactgtcgg gcttgttccg ggtgaggtaa taatccgtaa aacccaggtc ggcggcgatc
    18301 ttgttgtgcc ggcgcgtcgg ctgtatgtcg tccggcgtaa gcatggccga gaggctgtcg
    18361 tagtaggtgc gtgccatagc cggctgccgg agcagcaggt aagcgtccgt catatccttg
    18421 taataatgat gacggtacac cgtattgttc accatgtagc tccgggcctc tttcgcgtac
    18481 cggaggccat tatcggcctg ttccagttca aagtacattt cggccaggtt catcaggtcg
    18541 gataccacgt attcgcggtc tttcaccttt ccctgcgcga tgagcttttt ctttaattcg
    18601 atggattcca gcaggtagcg gacctgcttt tcatattcac cgcgtatcga atagtagttc
    18661 tggatcgaag aatacagttc gactttgtcc atcggatcgc gcagcgtgtc cacgatcgcc
    18721 agggcctctt tcagcgcagc ttcgctttta gccttgaaac cggccacatt gttgtataaa
    18781 aaaagcagcc ggtcgagcga ctggaccgtt tgccgcgtgt cgcgggcctt tttggcatag
    18841 tccagcgact tttcgtaaat gcggaaacag ctgtctgatt tcgaagtggt ttccaatgcg
    18901 aatcccagct ggtaatgaaa caatgcaagc cgtttcgcgt cgttggccgg ggtcagttta
    18961 atggcataaa gcgccacgtc atgcagcgcg acatgctttt cggccagtat aagcgagtcg
    19021 ccgattttgg cgagccgttc cagtttggcc gtcgtcgttt tgtatttcga aagatcgggc
    19081 aggggctggg caaatgcctg caacgccgca aaaagcccga aaataaaagg tagagttctt
    19141 ttcatcggct acaatttcag tttggaaagc gccgaacgat aggttttgcc gatggggata
    19201 atggcgcggt cgcataccag ttccgaatgc ctgagctcgc ggatctgccc gagcgacacg
    19261 gcgtagctcc ggtgtacccg caggaagcgg tcggagggca gctgctccat gaagcaggat
    19321 agcgtcgaaa gcgtcatgta attcttccca ggcgtcacga ttttggtgta atcctgcatc
    19381 gcttccaggt agatgatgtc acgctgggcc agtttcacct ggttatgccc ttccttgatc
    19441 gtgagcgtgt cctgctcgaa aagcacctcg taagcgtgcg atttttgccg catttcccaa
    19501 aaatccctga tccgcgcgac cgtagccgca aaccggtttt ccatgatcgg tttgagcaca
    19561 taatcaaggg ctgaaagttc gaaaccttcg agggcgaaat cggggtggga ggtaatgaaa
    19621 acggccatcg gcacctcttc ccggaacttt cggagcagtt cgataccggt aaatgccggc
    19681 atttcgatgt cgaggaacac caggtcgggc ctgatgtatt gctgcgcttc gtacccttcg
    19741 agcgggttcg tgaacgtgcc gcaattttcg agaaaagggt aggcgcttac catttcttcc
    19801 agaaacagca gatcgagcgg gttatcgtcg atcgctataa accggatacg tgaaggagga
    19861 ggagtcatga aagggtgcag tcggattttt gtacccaata tatacaaaaa gcatttgcaa
    19921 agtgctggtt ccgactgaca agcctacatg atgattgagc gaaaggtttt gagaagttaa
    19981 attgacggtg tggaaagcgg catcattccg gcacgagctc gtactcgttt acggtattgc
    20041 ccgttttttt gctttcgttg gtgcgtttca gcaggagcct gccggcggcc ggtggttcgg
    20101 tcaggtaaaa ttcgatgtta cccgccgatt cgctgggtgg tggcgtgaga ttttcgagga
    20161 tcagacggcc attgtccggc gagagcgacc attttcccgt cagctttcgg ccgtcgatgt
    20221 ccataaatgt gacctgttcc ttgctcgtca ggtcgaggcg caggcgggcg tagccggggc
    20281 gcgtgctggc ggggttgccc gcggtgtaca cgagcgtacc gttttccttc acggattgtg
    20341 ccttccagac gaggccgata ttggccggtt ctacctgttt aggctggcag gctgcgagta
    20401 atgcaatgga aatgaggtat ataagctttt tcatgtcaaa acagtctgag gtgaatgccg
    20461 gcggtttacc ggatgaatac tttttgttta accaggatct tttccccatc caggaccgcc
    20521 acgtaaatgc ccggcagcca ggcattcagg tcgatctgca tctgttggga cagcggccag
    20581 gaacggacca aaaccccgcg tgcatcgtac aaatgcagtt ttccggaagc gggacggacc
    20641 agggcaatat gcaggcggtt gttatgggtg taaaccaaac cctccggtgc cacaggctcg
    20701 acgcccgtga taatggcgcc ggccggtacc ttcgccacgt cgctgtaagg agattcaccg
    20761 ttgctgttga cggccttgac ccggtagtag taatcgtgaa tatcaaggat ttcgcggtcg
    20821 ggaaactgga tgttggccgc cgcctggctg ccgatttttg caaatcccgc attcggctgc
    20881 tgcgaacgtt cgatgaccac cgtctccgca ttggccgaca atgcattcca tttcaactga
    20941 atcaggtcga agctcatcgg tgtcgccgtc aggccggtcg gtttgtccgg caccggcgcc
    21001 cgtggcgtag tagcgctcat cgtttcggag tagcccgacg gcccgatcgc attcacggcg
    21061 cggacgcgga aatagtaggt cgtgagttgt ttcaaatcct tgatttccag gttttgtata
    21121 ttgctcaaag tcgatgcgat cttggaaaac tgcgtgccgt tcgtggagct ttctatttca
    21181 aaacccgtct cattatcaga cacatcgccc cagctaagat tgatttgctg ataagaaacc
    21241 gccacggctg agcccgcgcg cggggtatta ggcgcgatat cgggtgtaac ggcctccacg
    21301 acattggaat agtccgaaaa accgccgccg ttgcgggcga ccacacggta ccagtattta
    21361 cggttcggct gcacaccgct gtcggtaaaa tcggctgcat tcgcattcgt ttcaccgatt
    21421 ttggaaaatt gggtaccatt atccgaccgc tccacgtcga agccggcttc gttatcggca
    21481 ttgtcctgcc atttcaggtc cacctggccg ctgctgatga ctttcgcgga aagattggca
    21541 ggagcaccgg gcctgggaat ggccaggtta acgcagcctt cattggaata gcccgactcc
    21601 ccgcccgcat tcactgcctt cacccgatag cagtagcgat tgccgggtga aacattgttg
    21661 tcgttgtagc tcagcgaccg ggcgtaaggc accgtcgcga tcgtaccgaa tccgccgcca
    21721 ttatccgagc gttcgaggat gaagcgcgca ttgtcgctgt tgtttccctg ccaggtaatg
    21781 gccacgccac ggcccgaaat gtagaatact tcgaggttac ccggcgtcgc tgccggggca
    21841 aacggcgtcg ttacccgtgc ttcgttgaac tccccgccgc aggatttttc gcagtaggcc
    21901 ttcacacggt aaatgtaggt gcggttttcc tgcacggttt tgtcctggta ggcaaatgtg
    21961 cctctcggaa cgttgcgcgc gatgttggcg aagttctggc ccggaccgtc ttcttttcgc
    22021 tcaatctcgt acaattcggc agttccgggc aggcggtccc acgacaaatc gacttgctgg
    22081 tacgacaccg ccgtggcgcg cagcatcgcg cgctgggcat gccccgtggt tgaaaacgcc
    22141 agcatggccg tgaggcagag caaggtgctg gtaatggggg atagtatgcg attgttcatt
    22201 ggctcggtaa catgattaag agattcattt ccaatccact ttcacgggat cggtaggggc
    22261 gctttcgcgg ttgtcggtac cgacggccac gacatggtaa tagtacccga cgcccgccac
    22321 ggcatcgcgg tcgatgtagc ccgtttgcgt gcccaggggc gcactcacga ggcggggctt
    22381 ttcggttttt tccgtgtagc ggtacacgag gtatttgtcg ggtttggcta atggggcgtc
    22441 ccagctcacg agcacgccgc ggttggtggt cgcgacattc agtccatgca cgggcagcac
    22501 ggcgtcgtgc ggctggtagt aacctatttc cgtgctgaat gcgctcaggc ggccgcccat
    22561 gccgtaggcg cggatgcggt agctgtaatg cacgccctgt ttcacggtgc tgtcggcgta
    22621 gtggttgcgc gcctggtctt ctgcatgctg gcggtatatt tccttgaatg ccttttcatt
    22681 ttccgctttt ctttcgatga tgtagcccag tgtgtaggga tcgatggctt tcatgttttc
    22741 ccaaacgagc caggcattac ccggctggtc gatcagttcg ggattgagcg gcgtggcgag
    22801 gcgggtgggg aagcggggtt cggaatagag ctcgttgctc atcgggccct ggttgtagct
    22861 cgtgttcacg gccacgacgg cccagcggta ggccacgccg atggcgagtt tttgcacggg
    22921 gatctggtat ttcaatgcgg catgggccgg gatcatgtcc gaaaactgct gcaaggtgtc
    22981 cgtttgcccg gcggcgaagt agatgtaata gccgtgcgtg tcgaaatcgg ctgcttccca
    23041 gcggaaggtg agcgaatctt gggtttcagt cagttgaaag tgcgccggcg caagcagtgc
    23101 cgggcggttg gctttgagca ttcccgatac tttcacggac gcgggcgagg attcgtaagt
    23161 gccgttcagc cgcacctggt agtagtaacc ctgcaccggt tccacggcgt ggtcggtgta
    23221 agccgtatct gtcgccgccg ccacgccgac ccttttaaaa cccgtgtcga aatcttcgct
    23281 gcgccatatt tccacggccc gcaggtcttt caccgacgac agttcccaac tgacggtgat
    23341 cgcattgtcg ctctccacgg agcgcgtgct gatgcggtgt atgacgggga tttcgtcttg
    23401 tgcgcgcagg ttcgcgaggg tgagtgtatc cgaagcggcg ctttcgttcc cgacgaaatc
    23461 ttggagatac accacatagg agtacagcat tttccggcgc acattcgggt cggtcacgac
    23521 gaggaagagg gagtctcttt cacctttgcg gaagccccat tcggcgccgc attcctcgaa
    23581 tcccgtttgt ccgaaagcgg cacgcagcac ccgtgcgccc gcaatgtagg ggtttggttt
    23641 cttgattaaa tactgaatgc tgacggtgcg gccatcggta tggcggctca cggaccgtgc
    23701 cgtggtggcg agtttcgcgc cgggaacgga taccgtgccg ggattgtggt aaacgccctc
    23761 cctcgcaccc aatgcccgca gtcggtagtc gtagcgcagg ccttgctgca cgccggtgtc
    23821 gaggaagccc agcccgagcg cttccaggta ttgcgggttg gacccgtagc cgcccagcga
    23881 atcggcgtgg gctacgttcc ggtaacgatc gaacagcaag gtggtcagcg agtcgttcgg
    23941 gagctggtac aacgggtttt tggcggcgag taccgtgagg cgcgccgtaa gttcggccgc
    24001 attggcgggg cctttgccgg tcgtacatac gggctgccat tcgggcttgt ttttgccggt
    24061 ttccagtcgc tcgatcacat attgcgggcc gtgaagcagt ttgtctattt gaataaacac
    24121 gccatacggg ccaccgatgg cttgtggctt ttgtgcctgc aatgcggctg tgccaaggca
    24181 gaagagcgtg aggatgcgaa tgattgtttt catatcgatg gatcgttatt ctttcaccag
    24241 gcagccggtg tcgcatttgg taaaggtgca ttcggggctg atctgcaagc cggggctgcc
    24301 gccgatcgtg tagttggccg agccgttgag tttgaggcag aaatcggcgg aggtgcccgt
    24361 cgaaagcccg ctgaggtctt cggtaagcgt caccgaaaag cccgcgctga ggcgcgaatc
    24421 cagggttacc gacacatttt tgggaccggt atcgacggtc agcttcgtat ccacgccgcc
    24481 gttcacatgc acctcgccgc ccgcgctgac ggagagcacg ctcccgtatg cataggcatg
    24541 cgcgccaatg cccatgccgc cgcccacgga gaatgcgcca ttgtcgtaat tgccgtacac
    24601 gtagccgtcc acataggcat ccat
//
