LOCUS       c00002_NZ_JAJF..       23849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJFOJ010000002.1 Roseburia inulinivorans DSM 16841 strain
            FDAARGOS_1587 ctg.s1.000001F_arrow_pilon, whole genome shotgun
            sequence.
ACCESSION   c00002_NZ_JAJF..
VERSION     c00002_NZ_JAJF..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:59:55
            Original ID  :: NZ_JAJFOJ010000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1367581
            Orig. end    :: 1391430
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23849
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1377581:1381430]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..23849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="4"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(55..1752)
                     /locus_tag="ctg2_1261"
                     /transl_table=11
                     /translation="MSQISQIKKIYHAAIYVRLSKEDGAVASHEKTESNSIANQKSLIR
                     DFLENKNDIEVVQEYVDDGFSGSNFERPAFQMMLEDIKKGKIDCVVTKDLSRFGREYID
                     SGMYIERLFPAMGVRFIAINDGIDSGEAKSQSDEIIIPFKNLINDAYCRDISIKIRSHL
                     EIKRKQGDVITAFVPYGYKKNDKDKHKLEIDVYAANVVKDIFRMKLHGKSQDAIACELN
                     SSGILPPAEYKASTGSNYQTCFKTKEKSEWTSVMVRRILTNEVYIGNLVQGKQTTPNHK
                     VKKTIIKEKCEWIRIEKNHEPVITDRDFEVVQRLLAMDTRTSPDREEVYPLSGVVTCGG
                     CGIPMVRKTSKVGGKTYAYYLCATHKDSKQCSSHRISTDKLEEVVLELLQTHIDNMIDL
                     KRILSFIGNVPFQQLDMKKLEERREKKQAEVDRCADLRGMLYEDMKDGIISKEDYKELH
                     TAYEQRKKSAEIAIHQIELEMEDVLNRKSKGFVWLDYFTEHKNIEKLTREVVVSLIREI
                     KVFDKTHIEVVFDFDDCYKECLNVIASQGHSVEVDSTGKLNIRLKEAV"
     PFAM_domain     complement(583..762)
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1261_0079"
                     /evalue="3.20E-16"
                     /label="ctg2_1261"
                     /locus_tag="ctg2_1261"
                     /protein_end="390"
                     /protein_start="330"
                     /score="59.6"
                     /tool="antismash"
                     /translation="PLSGVVTCGGCGIPMVRKTSKVGGKTYAYYLCATHKDSKQCSSHR
                     ISTDKLEEVVLELLQ"
     PFAM_domain     complement(805..1161)
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1261_0078"
                     /evalue="1.80E-21"
                     /label="ctg2_1261"
                     /locus_tag="ctg2_1261"
                     /protein_end="316"
                     /protein_start="197"
                     /score="76.6"
                     /tool="antismash"
                     /translation="ANVVKDIFRMKLHGKSQDAIACELNSSGILPPAEYKASTGSNYQT
                     CFKTKEKSEWTSVMVRRILTNEVYIGNLVQGKQTTPNHKVKKTIIKEKCEWIRIEKNHE
                     PVITDRDFEVVQRLL"
     PFAM_domain     complement(1240..1716)
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1261_0077"
                     /evalue="2.10E-23"
                     /label="ctg2_1261"
                     /locus_tag="ctg2_1261"
                     /protein_end="171"
                     /protein_start="12"
                     /score="83.1"
                     /tool="antismash"
                     /translation="AAIYVRLSKEDGAVASHEKTESNSIANQKSLIRDFLENKNDIEVV
                     QEYVDDGFSGSNFERPAFQMMLEDIKKGKIDCVVTKDLSRFGREYIDSGMYIERLFPAM
                     GVRFIAINDGIDSGEAKSQSDEIIIPFKNLINDAYCRDISIKIRSHLEIKRKQGD"
     CDS             complement(1879..2127)
                     /locus_tag="ctg2_1262"
                     /transl_table=11
                     /translation="MTAEEYRALLDVDFNNVKIEDLTDIRKIKIDKNQPQSKRQAQFLK
                     QVGNPYMLRRGSMMIKVSFANNGLSMEQAFENLLLNV"
     CDS             complement(2210..2596)
                     /locus_tag="ctg2_1263"
                     /transl_table=11
                     /translation="MKLNRGDIVIANLESVSKGSIQKYTRPYIIISNNKANQYSPVVTA
                     VAMSTKTWKKKYLPTHCPIPAAKVKVTDTDFEVFDSMALCEQIVSIDVNVHIERVVASI
                     SDTELLDKITECVKIQIGAYEKYN"
     PFAM_domain     complement(2237..2584)
                     /aSDomain="PemK_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02452.19"
                     /description="PemK-like, MazF-like toxin of type II
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1263_0080"
                     /evalue="2.10E-19"
                     /label="ctg2_1263"
                     /locus_tag="ctg2_1263"
                     /protein_end="120"
                     /protein_start="4"
                     /score="70.0"
                     /tool="antismash"
                     /translation="RGDIVIANLESVSKGSIQKYTRPYIIISNNKANQYSPVVTAVAMS
                     TKTWKKKYLPTHCPIPAAKVKVTDTDFEVFDSMALCEQIVSIDVNVHIERVVASISDTE
                     LLDKITECVKIQ"
     CDS             complement(2602..2769)
                     /locus_tag="ctg2_1264"
                     /transl_table=11
                     /translation="MNLLSFLMNDMTEENRKLKLIIFPGETVVIDEYGKRIVACPTEDE
                     AEEYIREQEE"
     CDS             complement(2741..3061)
                     /locus_tag="ctg2_1265"
                     /transl_table=11
                     /translation="MQDSKEKQCLIFVRNNANDTADRIEAYAKKSGMKVVETIFNTDKK
                     AVERLRYYIERDVIICVLVRDVVDISMELNEIKAVMTLAAEHGISINAESRGYEPALIS
                     YE"
     CDS             complement(3070..3492)
                     /locus_tag="ctg2_1266"
                     /transl_table=11
                     /translation="MERAIIYYAKTGLEATDHFVPKLLEKYCQDNGYEIVAMLSEPAST
                     EGVSFPMKYAIIGLNMEEDVNTIITLSKDMIGATDETVIDTLGKLSEYDIYVEDINGEL
                     EECYEMMYKEPVQESDIRGLVLDTVSKFYHNIRDGR"
     CDS             complement(4144..4467)
                     /locus_tag="ctg2_1267"
                     /transl_table=11
                     /translation="VYYDIVNSGERIKELRAARRMTRQQLAEQIGLSVDALRKIEAGVN
                     GAKIDTLISIAELFHITLDYLVCGCERKAEVDDLLVGLKEKEVQFIRNMVLNAVDNMKL
                     LTE"
     PFAM_domain     complement(4270..4434)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1267_0081"
                     /evalue="2.00E-12"
                     /label="ctg2_1267"
                     /locus_tag="ctg2_1267"
                     /protein_end="66"
                     /protein_start="11"
                     /score="47.1"
                     /tool="antismash"
                     /translation="IKELRAARRMTRQQLAEQIGLSVDALRKIEAGVNGAKIDTLISIA
                     ELFHITLDYL"
     CDS             complement(4660..4872)
                     /locus_tag="ctg2_1268"
                     /transl_table=11
                     /translation="MIVYDRLWITLKKKNISQYALIKDYGIDKAQLQRLRKNMVVKTVI
                     LNRLCSILDCKIEDIMEFVPDEDIK"
     PFAM_domain     complement(4675..4857)
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1268_0082"
                     /evalue="4.90E-17"
                     /label="ctg2_1268"
                     /locus_tag="ctg2_1268"
                     /protein_end="66"
                     /protein_start="5"
                     /score="62.2"
                     /tool="antismash"
                     /translation="RLWITLKKKNISQYALIKDYGIDKAQLQRLRKNMVVKTVILNRLC
                     SILDCKIEDIMEFVPD"
     CDS             5121..5354
                     /locus_tag="ctg2_1269"
                     /transl_table=11
                     /translation="MNDKNTYSVDKYLEIIAEKEGITKEEVQQEIGRAVSIALKSPDPK
                     MQRFWTDFPCENDTPTIEEIIYHLAEKFAKES"
     CDS             complement(5379..5723)
                     /locus_tag="ctg2_1270"
                     /transl_table=11
                     /translation="MGKREHIYEIIAENIRKERRRLGITQAELAERADVSLDTIKSVEN
                     GRRAMSLDTYLNIVHALESSPMVLMSQQHPEKHIERFAFMMNRCDEREIEFALHMIEQI
                     LRGQEDYLSE"
     PFAM_domain     complement(5526..5681)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1270_0083"
                     /evalue="6.90E-10"
                     /label="ctg2_1270"
                     /locus_tag="ctg2_1270"
                     /protein_end="66"
                     /protein_start="14"
                     /score="38.9"
                     /tool="antismash"
                     /translation="IRKERRRLGITQAELAERADVSLDTIKSVENGRRAMSLDTYLNIV
                     HALESSP"
     CDS             complement(5984..6598)
                     /locus_tag="ctg2_1271"
                     /transl_table=11
                     /translation="MKKIISMVLSFILILGCSTTAFAAETHNYDTENLPHDGADYFETE
                     IKADEENEERISDFVTVYGYQYTKGSLKSGAWRNGTSGGSSTSSAKLSLNYTQDTSYNI
                     SFKASVSGGYTNGGTIGSELGVTLGASKSYSLGSGYSVTVPKGSHYLIKYRPMYYTYKV
                     VETKYKERYNEALGGMERYVVETKTCYVDVFSHWDFTHVAK"
     CDS             complement(6605..6868)
                     /locus_tag="ctg2_1272"
                     /transl_table=11
                     /translation="MKDFHLKILAIIMIIFGIFGLSTLPFLSIIVQYIDSITGFSSGNG
                     YLTNNMDYLFKSPLIYIGGFFVFSIILAIIYLVYSFFKAKRG"
     CDS             complement(7357..8043)
                     /locus_tag="ctg2_1273"
                     /transl_table=11
                     /translation="MVNMVNTAVNNNIYAGRKSGSKYNQSKAFQQKEVLETPDVAAVNK
                     YANVQEIYEALKCNVSCRGYEQGQDEIAEKEIQNDEPEISNDSSEKMTVWYQGVPLEEW
                     ALTDPKYTDSETGISWYIRDGKYPYMVGEDAEKFRKLCEESGEFALKKFAEMTGLIQKL
                     DDNTVAYVGDNGIAVKSKDGKEMFVDTSGLSYDIVMDMFRNLPRNGNFFSNKYWSDNIQ
                     KAQARS"
     CDS             complement(8183..8722)
                     /locus_tag="ctg2_1274"
                     /transl_table=11
                     /translation="MKKVKSLKALVLSLMLCLAMGTTAFASEVSTQGQAAPNANKAVEV
                     SDCGDLDVVPAYDDAVALADTIQYDANRTITRSNSRSGVFNGNYYYTINNSSVTKLCLN
                     VYMPNESGTDYLQGTITLVGNDGTSAPVQIANYSGDSWTLTFTGVKVGVRYHFHYELYS
                     VGSSQVGYIASAAYAQ"
     CDS             complement(8788..9315)
                     /locus_tag="ctg2_1275"
                     /transl_table=11
                     /translation="MRIGSGVQSVSELFGKRQNNSKTSVNGNEAFPQTSMKVYLKTDDM
                     LFSGGNGTGLSFYIKYAEESTDDNPVVIAKGIDENGKEFEEKININDIDLRNASYVEMS
                     ALEAYYDVDRGNSLSSFPQETGHMGLNERCDLISSFEKVIQDMNKLGKYDLQMFYMRNM
                     NTYLNLERQKKA"
     CDS             complement(9368..9856)
                     /locus_tag="ctg2_1276"
                     /transl_table=11
                     /translation="MLMGMGTMVSAAEKESSIPEYSETNDGGMTVNIAGDQEGTIVEGS
                     GNEEGINPLWWPGDGPAPQVTSISLYKYGWLTNGNFGVTIKVYGYGSDTTTFDGRSISW
                     IHQEPFIISGTGADGFYYTYDCGPITQAGSYRFNTTFRSTNFPNTTRSFSTVFTFSAN"
     CDS             complement(10001..10150)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1277"
                     /sec_met_domain="TIGR04223 (E-value: 3.5e-06, bitscore:
                     23.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVNKKVLKVVEHVMRNEAVYGIDRFPPACMGIFHQPKRPIIQK
                     KSER"
     aSDomain        complement(10028..10135)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_1277_0011"
                     /evalue="1.10E-05"
                     /identifier="TIGR04223"
                     /label="ctg2_1277"
                     /locus_tag="ctg2_1277"
                     /protein_end="41"
                     /protein_start="5"
                     /score="23.4"
                     /tool="antismash"
                     /translation="KKVLKVVEHVMRNEAVYGIDRFPPACMGIFHQPKRP"
     CDS             complement(10147..10728)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1278"
                     /sec_met_domain="AgrB (E-value: 8.5e-32, bitscore: 106.4,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKIADDLIGQMTEARLIDKEMEARYVYVFICWIEKFITVGSII
                     VISLMFHKLLPTIFFLVFFLELRKRTGGYHLDKFYRCYLASIVSYLVIVIISEKLSEHP
                     QWLFAIVLLAITGIGLIGTANHPNMHMTSDELMESKKSARTIVLLEGCIILGCVLLDAD
                     MVYVSYMAIAVILCAALLCIAKIFKQEVKE"
     PFAM_domain     complement(10180..10713)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1278_0084"
                     /evalue="6.70E-30"
                     /label="ctg2_1278"
                     /locus_tag="ctg2_1278"
                     /protein_end="183"
                     /protein_start="5"
                     /score="103.9"
                     /tool="antismash"
                     /translation="ADDLIGQMTEARLIDKEMEARYVYVFICWIEKFITVGSIIVISLM
                     FHKLLPTIFFLVFFLELRKRTGGYHLDKFYRCYLASIVSYLVIVIISEKLSEHPQWLFA
                     IVLLAITGIGLIGTANHPNMHMTSDELMESKKSARTIVLLEGCIILGCVLLDADMVYVS
                     YMAIAVILCAALLCI"
     CDS             complement(10866..12170)
                     /locus_tag="ctg2_1279"
                     /transl_table=11
                     /translation="MLISYIQSIMMIILEVICCKIFFESFAEKRSKNNYRNYSIILGIV
                     VCEYVIASLFYDKFILKQILAIVAVAVFMCFYFKIHFGKAIILSLLFQALLLSVDYFTL
                     WLNVSLFDSIAEISRLHFVGGSLITVLGKIILFLVVLLIRKKVGGESSDVLRSTDWLRF
                     IFFPVFTIFTVIALIMTSGNIENQKQENVFLVIALCLAGMNIVVFYMINDILKREIKIR
                     ENEVFQLKARNQTDMYRSISENFVKQRKKTHEYKNQIMCIESLIEMENYDELKDYVKSI
                     SGNLSTELDYIKTNNVIIDAILNSKYKETLDKGIVFIFQINDLSGIKMCDEDIVVILSN
                     LLNNAIEACEKCSGKKFMKMKLVKEKDNIIISVKNTYDGKLNIKDGEIQTSKKYEMDEH
                     GVGIKNIIEVITKYQGSYAIRNDNNEFYFSVILPN"
     PFAM_domain     complement(10872..11180)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1279_0085"
                     /evalue="3.70E-25"
                     /label="ctg2_1279"
                     /locus_tag="ctg2_1279"
                     /protein_end="433"
                     /protein_start="330"
                     /score="87.8"
                     /tool="antismash"
                     /translation="DEDIVVILSNLLNNAIEACEKCSGKKFMKMKLVKEKDNIIISVKN
                     TYDGKLNIKDGEIQTSKKYEMDEHGVGIKNIIEVITKYQGSYAIRNDNNEFYFSVILP"
     CDS             complement(12171..12929)
                     /locus_tag="ctg2_1280"
                     /transl_table=11
                     /translation="MSNLCVEGDEHMFRIAICDDERQFRKRIHDILIEYMNENDILYEI
                     DEFESGKDFISLGINLAKYDIVFLDVNMDELDGMETAQKIRKVSNDVFIVFVTAFITCA
                     PQGYSVGAIRYILKNNVNFPELIFECMDAISLNMNYVAQKKKFNFNEGTKIVALERLLY
                     IESRLHKLEFYIMEDKLKKYSIYGKLDELEKELQGNDFIRIHQSYLVNMKHIEKVSRYE
                     ALLNNGIKLEIPKARYKFVEETFVSYKGEL"
     PFAM_domain     complement(12207..12473)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1280_0087"
                     /evalue="5.90E-16"
                     /label="ctg2_1280"
                     /locus_tag="ctg2_1280"
                     /protein_end="241"
                     /protein_start="152"
                     /score="58.6"
                     /tool="antismash"
                     /translation="TKIVALERLLYIESRLHKLEFYIMEDKLKKYSIYGKLDELEKELQ
                     GNDFIRIHQSYLVNMKHIEKVSRYEALLNNGIKLEIPKARYKFV"
     PFAM_domain     complement(12573..12887)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1280_0086"
                     /evalue="7.20E-16"
                     /label="ctg2_1280"
                     /locus_tag="ctg2_1280"
                     /protein_end="119"
                     /protein_start="14"
                     /score="58.4"
                     /tool="antismash"
                     /translation="IAICDDERQFRKRIHDILIEYMNENDILYEIDEFESGKDFISLGI
                     NLAKYDIVFLDVNMDELDGMETAQKIRKVSNDVFIVFVTAFITCAPQGYSVGAIRYILK
                     N"
     CDS             complement(13086..13670)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1281"
                     /sec_met_domain="AgrB (E-value: 3.9e-39, bitscore: 130.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAKFAKKINEILIQKGIVQKEEAELYQYGIENGIVVAGNLLASG
                     IFGIVTGRPGLVLVFLLFYASLRSYSGGSHCKSRIGCFLISMAILFIPVYTYEPVMKNV
                     PNALILLIGVLAVVIIIVLAPVESINKPLDEEERRYYARVTHCITALQVCVLIILFCLD
                     LQDYFYAGYVSIVLIAVFMVMGKIAVKRYVQ"
     PFAM_domain     complement(13122..13655)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1281_0088"
                     /evalue="8.20E-38"
                     /label="ctg2_1281"
                     /locus_tag="ctg2_1281"
                     /protein_end="183"
                     /protein_start="5"
                     /score="129.7"
                     /tool="antismash"
                     /translation="AKKINEILIQKGIVQKEEAELYQYGIENGIVVAGNLLASGIFGIV
                     TGRPGLVLVFLLFYASLRSYSGGSHCKSRIGCFLISMAILFIPVYTYEPVMKNVPNALI
                     LLIGVLAVVIIIVLAPVESINKPLDEEERRYYARVTHCITALQVCVLIILFCLDLQDYF
                     YAGYVSIVLIAVFMV"
     CDS             complement(13685..13849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1282"
                     /sec_met_domain="TIGR04223 (E-value: 1.4e-10, bitscore:
                     37.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLRRLMNRLSHGALSSVAALALTVTATNMNRCCWFIFGQDKLP
                     DNAKKLRKF"
     aSDomain        complement(13700..13807)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_1282_0012"
                     /evalue="4.50E-10"
                     /identifier="TIGR04223"
                     /label="ctg2_1282"
                     /locus_tag="ctg2_1282"
                     /protein_end="50"
                     /protein_start="14"
                     /score="37.4"
                     /tool="antismash"
                     /translation="ALSSVAALALTVTATNMNRCCWFIFGQDKLPDNAKK"
     CDS             complement(13953..14915)
                     /locus_tag="ctg2_1283"
                     /transl_table=11
                     /translation="MGESYKYYFVMVICSFVRGNVMYILSKLISKKGMQIADFPKEILG
                     VLVMVFAFTVLNCCFVILLSLEAGSEKSLLMCASIVISIVLTDYFMLYMMERFNYLVQK
                     QYEDAMYREEMHYKDIYYEEAEKQNKEVQKLKHDMKHKLHELYYLVENSDGQELSEKIG
                     AMCKEFEQIDEKQYSDNPIVDSVLRIKFGRAKARGIKVETSIRIPKQMQLDHGDIGVLY
                     GNLVDNAVEACSKVPEGQRFVKIENKYQSGILLLVITNSKTGKKNKSLKTTKKDNIRHG
                     HGVQSVRKVIEKYNGTVSFTDKGDIFEVSAMLYGIEVRE"
     PFAM_domain     complement(13977..14270)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1283_0089"
                     /evalue="9.00E-23"
                     /label="ctg2_1283"
                     /locus_tag="ctg2_1283"
                     /protein_end="313"
                     /protein_start="215"
                     /score="80.2"
                     /tool="antismash"
                     /translation="GDIGVLYGNLVDNAVEACSKVPEGQRFVKIENKYQSGILLLVITN
                     SKTGKKNKSLKTTKKDNIRHGHGVQSVRKVIEKYNGTVSFTDKGDIFEVSAML"
     CDS             complement(14885..15238)
                     /locus_tag="ctg2_1284"
                     /transl_table=11
                     /translation="MSNTINVNYMTRAYNQYQQKNAAKDQEKEDTRFADSVREKSEASG
                     SIVGNSKIGSVSAKDMTMVEYKQYIYNKISQIPMHPTRAGESISVTISEAGFEAMKNDP
                     EYEAWEKVINIIL"
     CDS             complement(15648..16565)
                     /locus_tag="ctg2_1285"
                     /transl_table=11
                     /translation="MTKRDKPAMSEEEFEKAIKELAQKEFATGKRDDAAYRKLCMQHGE
                     TVSPDRKTIYESSMRKTGGKMNAACMFWDNNGNKTLSYNPESRNWKAISTEEEFARARV
                     FTSIYNDELARLKKEYGENAKGTRATLNARGAIIEINNIELYQGGNCMGVDSILGGNFS
                     VQTKDFTKRTTSGATDVNQTQGLSESEKLENFKKEIWKEIDSMSWGSNISVQITNSAFE
                     KMMVDKEFKNKMMNIIREDAHGSNMMCGGTLINIDENGYKGYSYMQDHTKEAGRAFDAH
                     SKDKDSFYSKKCKKDELNELWERD"
     CDS             complement(16735..17340)
                     /locus_tag="ctg2_1286"
                     /transl_table=11
                     /translation="MQVNSSNGSLQQRIFSGTGSIGGVHLPDFNDKYVFSKKKSGISDE
                     EYRKQIVAQAYKDFEKGTFQNKSDGFNKLMKNYTSEVSPDRKGIITSGLKAVSRNRHNV
                     LKPIDFVATLLEGKVKYQKLPSGNSEYIEFYDKNGEMVATYSNNGWTMYTTNAEAARQT
                     EMCMIYNEAWGNAKRGLPIVGGESVNEENLKSSFDVKA"
     CDS             complement(17340..18017)
                     /locus_tag="ctg2_1287"
                     /transl_table=11
                     /translation="MSITFLSNPIHLPDFFKFDREYLGKQESQNEDQKVFHKDTLEVSQ
                     LSKNRENLMDKIKHTVVHSVTSFSDMRAGILKEIREEKGQYDYTDVVNACGLSYARLYS
                     EIEERYKNGNEQYYKSAGGTPWTKEEIEWLDMQYEQEVAWQKSCARIAARGQVFQGNIP
                     EVPTKEIEELEDSFYQAKDAYIKLYQESKQTGKFLVLQNYMLGSSRMYEMLNKLGNLQE
                     RVE"
     CDS             complement(18043..18705)
                     /locus_tag="ctg2_1288"
                     /transl_table=11
                     /translation="MAISGVGQSYYQNNVATTKSTKSVNSTEETGNTKELSEAEEMAIF
                     KKEFYAEIDKIPRNRTITNVAINISEEAFKNMKDDPEYREKILSALKRDLTSSFAPLEA
                     SMVLTVGATAKDYRGDSWSGVNNQSEFFARSQNSFYKKTSNKKDRQKELLEEYLEKRAQ
                     VKKQQQEMLNEKIAKQEQERSRLLRSWNNERLLSKASNAYEANAMTEAVTDSAFSLG"
     CDS             complement(18722..19453)
                     /locus_tag="ctg2_1289"
                     /transl_table=11
                     /translation="MAINGVGHNYDYLGTTTNYIRGKATVREAISKMVKQSANLSISDA
                     GRNMLREMASKFEPDSDYTNVRELTIQNTNEVAWEHYTAMRDISSLTLKDGNYNVEDVM
                     KSIMDTYETRYNEIVKEHENGDREVSYELTGKRSLTLDEDLAGLDEAFKMRLANLEGYI
                     TCQQTNKAFENADSSWYFRRNSPQNEVKTQDKAQMFDTKYQKTAVSIMEQAKEKFLVAF
                     KSINYKQGTATSILSDIMKKC"
     CDS             complement(19780..20145)
                     /locus_tag="ctg2_1290"
                     /transl_table=11
                     /translation="VQEYYEKLCKKFPEITFNTGSSLMSGNENKVVINLSSECLKKMAN
                     DPEFAKKVEFNLTGAVPGQNRMLAQAKADNAVIHGVTTVIDADGNASVTCGGMTRTSGS
                     KQNSTTLNAEKKEKERL"
     PFAM_domain     complement(19789..20142)
                     /aSDomain="DUF6033"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19498.1"
                     /description="Protein of unknown function (DUF6033)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1290_0090"
                     /evalue="6.60E-20"
                     /label="ctg2_1290"
                     /locus_tag="ctg2_1290"
                     /protein_end="119"
                     /protein_start="1"
                     /score="71.9"
                     /tool="antismash"
                     /translation="QEYYEKLCKKFPEITFNTGSSLMSGNENKVVINLSSECLKKMAND
                     PEFAKKVEFNLTGAVPGQNRMLAQAKADNAVIHGVTTVIDADGNASVTCGGMTRTSGSK
                     QNSTTLNAEKKEKE"
     CDS             complement(20252..21280)
                     /locus_tag="ctg2_1291"
                     /transl_table=11
                     /translation="MASVFKGLNVKIDAVSVWIGGYIMRIQAANTFYTGTYSVLNTKSS
                     FPYAVKVEGYGNTRNQRSLFQFAHVTITEHMVNAKYGTKITNGPRVQMQTAGSKKKEDW
                     TEVSKEQLAEVKLPASFDKLKEQNSYFYHGENISDYELVQTAVALGKMELPTDEKKCIP
                     DRVAMDAFEVLVRDQAAPKNSWSNTLYSEDGKYTFTKTESGRWQMHLIDDAAIGASLED
                     IANWMMSGTPNRNIETRYLNYLHTVDPDLYNVAMRIGSEVRSYGFMEDLHQQGVLSDSQ
                     NQYDMSLLGMLFGKDADSMRMILNGCKESGNFLELLDLYSPDGAKSLDKLREQQYKHGG
                     IV"
     CDS             complement(21363..21659)
                     /locus_tag="ctg2_1292"
                     /transl_table=11
                     /translation="MGNTKLGFMNVPNGDAIAFDMKESEINPSVVYLSHDDGEGHGYIL
                     GKDFNTYLEQLLLVGACGNEDWQMLPFCLDAQSGIVSDCENAKEYRKLIGLQI"
     CDS             complement(21665..21934)
                     /locus_tag="ctg2_1293"
                     /transl_table=11
                     /translation="MLEWSTDEDFWVRRIAIDHQLCRKERTNTELLEKILVNNFGSSEF
                     FINKAIGWSLRDYSKTNQDWVRNFVETHKDKMDKLSIREASKYL"
     PFAM_domain     complement(21668..21934)
                     /aSDomain="DNA_alkylation"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08713.13"
                     /description="DNA alkylation repair enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_1293_0091"
                     /evalue="5.20E-34"
                     /label="ctg2_1293"
                     /locus_tag="ctg2_1293"
                     /protein_end="89"
                     /protein_start="0"
                     /score="117.9"
                     /tool="antismash"
                     /translation="MLEWSTDEDFWVRRIAIDHQLCRKERTNTELLEKILVNNFGSSEF
                     FINKAIGWSLRDYSKTNQDWVRNFVETHKDKMDKLSIREASKYL"
     CDS             complement(21951..22286)
                     /locus_tag="ctg2_1294"
                     /transl_table=11
                     /translation="VLKTPIKLVDSSSLNRLSNSVNIASDMRIAVNDGYILKVKQQGVE
                     VSGGNDPYDTEAYMKAQKMAGSLSTLLRNACGNMHTVAYSQEEYARWTEGVSDVMGYLG
                     IDYSFYR"
     CDS             complement(22287..22433)
                     /locus_tag="ctg2_1295"
                     /transl_table=11
                     /translation="MEISNNQSYYINPNTRQFTSNVKNTAIKDREVFNGSMQNLLNPIE
                     DLV"
     CDS             complement(22417..23118)
                     /locus_tag="ctg2_1296"
                     /transl_table=11
                     /translation="MDVGSVYGSYYETAKSYMGLRKEEKQAGSAEKVTDKSQVSSEDMT
                     LEEYKEYFNEKMNSLYTHPSQRNRNDIIDITDAAYKRMQTDPEYEKKILDALAKNKAVN
                     FGNYIPQISYMHIDDTYEKCYGYTQGMKENDGYSGSSSAKGTDAGRQKKARQKELLEEY
                     LEKRAQAKKQQLEMLNKKIAKMELERSRQTQSWNSERQMAKASNAYDANIMMEAELVKN
                     ITKGENNGNFK"
ORIGIN
        1 tcagtcggct ctgcaactgc aaccggcata ttttttctgc tctttcttgc catactacac
       61 agcctccttt aatctgatat tcagttttcc tgtactgtcc acctcaaccg aatgcccctg
      121 acttgcaata acattaagac attctttgta gcagtcatca aagtcaaaca ctacttcaat
      181 gtgggtttta tcaaatacct ttatttcacg gataagagat acaaccactt cccttgtaag
      241 cttctcgata tttttatgtt ccgtaaaata atcaagccat acaaagcctt tgctcttacg
      301 attcagcaca tcttccattt ccaattcaat ctggtgaatg gcaatctcgg cactcttttt
      361 cctctgctca tatgctgtat gaagctcttt gtaatcttcc tttgagataa tgccatcctt
      421 catatcctca taaagcattc ctctgaggtc tgcacatctg tctacctctg cctgtttctt
      481 ttcacgcctt tcctcaagct ttttcatatc aagctgctga aacggcacgt tgccgataaa
      541 agaaagaatt cttttaaggt caatcatgtt atcaatgtgt gtctgtaaaa gctctagcac
      601 cacttcttcc aacttatccg tggaaattct gtgggaactg cactgctttg aatccttatg
      661 ggttgcacac agataatagg cataagtttt gccacccact tttgaagttt ttcttaccat
      721 gggaatccca cagccgccac aggtaactac ccctgacagc ggataaactt cctctctgtc
      781 cggtgatgtt cttgtatcca ttgcaagcaa tctctgtact acttcaaaat ccctgtccgt
      841 gataaccggc tcatggttct tttcaatcct tatccattcg catttttctt tgattatggt
      901 ctttttgacc ttgtgattcg gtgttgtctg ttttccctgt acgagattac ctatataaac
      961 ctcatttgta aggattctcc ttaccatgac tgaagtccac tccgactttt cttttgtctt
     1021 aaagcatgtc tgataattgc ttcctgtgct tgctttatac tcagccggtg gaagtattcc
     1081 tgatgaatta agttcacatg caattgcatc ctgacttttt ccatgcaact tcattctgaa
     1141 aatatctttc acaacatttg ctgcatatac atcaatttcc agtttgtgct tatctttatc
     1201 attctttttg tatccatatg gcacaaatgc cgtgattaca tctccctgct ttctcttaat
     1261 ttcaagatgt gaacgtatct taattgaaat atcacgacag taagcatcat taataagatt
     1321 tttgaatgga ataataatct catctgactg cgactttgcc tctccggaat caataccatc
     1381 attgattgca ataaatctta ctcccatagc agggaataat cgctcaatat acatacctga
     1441 atctatatat tctcttccga atctgctcag atccttagtg acaacgcaat caattttgcc
     1501 tttcttaata tcttcaagca tcatctggaa tgccggtcgc tcaaaattag agccgctgaa
     1561 accatcatca acatactcct gcacaacctc aatatcattt ttgttttcga gaaaatctct
     1621 aatcagtgat ttctgatttg cgatactgtt actctcagtt ttttcatgtg aagcaacagc
     1681 gccatcttcc ttcgataaac gaacatagat ggctgcatga tagatctttt tgatctgact
     1741 tatctgactc atatgcacat cctcctattg ttgtttaagt tagaagataa cttttcaata
     1801 aggtgatatg cactaattta gaatttttat accaaaaaca tcatagcaca tatcactttg
     1861 aaattccacc acaaattttc agacattcaa aagcagattt tcaaatgcct gttccatcga
     1921 cagtccatta ttcgcaaagc ttaccttaat catcatactt ccacgacgca gcatatatgg
     1981 atttcccacc tgttttaaga actgtgcctg cctcttactc tgtggctgat ttttatctat
     2041 tttaattttt ctaatatcag tcagatcttc tatttttaca ttgttaaaat ccacatctaa
     2101 tagtgctctg tattcttctg ctgtcataaa atctatcccc ctttcagtaa aaatgccacc
     2161 catagaatac aggtggctat gtaacccgga gcaaatgccc cggtaatatt taattgtact
     2221 tttcatatgc cccaatctgg atttttacac attcagtaat cttatcaagt agttccgtat
     2281 ctgaaattga agcaactacc ctctcaatat ggacatttac atcaatggat acaatctgct
     2341 cacataatgc catactgtca aatacctcaa aatctgtgtc agtaaccttt acctttgcag
     2401 ccggtattgg acagtgggtt ggcagatatt tctttttcca tgtttttgtg gacatggcta
     2461 ctgctgtgac aaccggtgaa tactgatttg ccttgttatt tgagataata atataaggtc
     2521 ttgtatactt ctgaatgctc cctttactta ctgactccag atttgcaata acaatgtcgc
     2581 ccctgttcag tttcatctat gtcattcctc ctgttccctg atatattctt ctgcctcatc
     2641 ctctgtcgga caggcaacaa tccgtttccc atattcatca atcactactg tttcgcccgg
     2701 aaatataatc agttttaatt ttctattttc ttctgtcata tcattcataa gaaatgagag
     2761 caggttcata gcccctgctc tctgcattaa tactgattcc atgttccgct gcaagtgtca
     2821 ttacagcttt aatctcatta agttccattg aaatgtctac cacatctctt actagcacac
     2881 agataatgac atctctttca atataatatc ttaatcgttc aaccgctttt ttatctgtat
     2941 taaaaattgt ctcaacaact ttcatgccgg acttttttgc atatgcctcg atacggtcag
     3001 ctgtatcatt tgcattattc cttacaaata tcagacactg cttttctttg gaatcctgca
     3061 tattgcctcc tatctgccgt ccctgatgtt atgatagaac tttgataccg tatcaagcac
     3121 cagccctctt atatcacttt cctgaacagg ctctttgtac atcatctcat aacactcttc
     3181 aagttctcca ttaatatcct ccacatagat atcatattcg ctgagttttc caagtgtatc
     3241 aataacggtc tcatctgttg caccaatcat atcctttgaa agtgttatga ttgtattaac
     3301 atcttcttcc atatttaaac caataatggc atatttcatc ggaaatgaaa ctccttctgt
     3361 agaagcaggc tctgaaagca tagctacaat ttcatagcca ttatcctgac aatacttttc
     3421 aagcaacttc ggcacaaaat gatctgtagc ctctaatcct gtttttgcat aatatataat
     3481 tgctctttcc atcttaaaat ctccttataa ataatattga tttgatactg tgcgcacttt
     3541 atctcctcac ataagctgac ttatctgtac tctccacacc atcacaccta aacatttctt
     3601 ttctgtcggt gaccataaat cagtttgtgt gggaagataa aatactatct tcccggtttc
     3661 ttaaccatcc ccgtatcggg taacatatcc tttgccagcc acaaacactt cgtagtttcc
     3721 tgcccatctg gacttacgaa agtagccact ctctgaaaat gcgttttgct gaaattcagg
     3781 tgcacttatt atctcattac ctccggctgc taacccggta ggcacaaccc tctgctctta
     3841 tccttaaagg ctcctgctgt tacgtttctc ataatcggct acagctctga ggatagtcat
     3901 cgcacgaaat gggattctgc caccctgtca tagacaaggc gatataagct cgtgggatat
     3961 gcgtgtccta ttctgttttc aatattcaac ggttcttttc tcagaacctg aacaaagtat
     4021 aactgacacc acgcatcttc tacagtaacc gacactcttt tgaactaaga gtaacactcc
     4081 cacctgttcc aaatccttat aaaaaaagcc ggactgcatt atcaaaaatg caatccgact
     4141 tttttattct gtcagaagtt tcatattgtc aacggcattt aataccatat tccggataaa
     4201 ctgtacttcc ttctccttca gaccaaccag cagatcatcg acttctgcct ttctttcaca
     4261 cccacacaca agataatcca acgttatatg aaacaattca gcaatactaa tcagcgtatc
     4321 tatttttgct ccatttacac cagcttcaat tttccgcaga gcatccactg acaatccaat
     4381 ctgctcggca agctgctgtc ttgtcattct tcttgccgca cgcaactctt ttattctttc
     4441 tccactatta acaatatcgt agtacacctt ccactctttt ccggcacctt atatatttgc
     4501 ttaagctgta ttcattgtac cgtaagcgaa tcttttgtaa gagtgactaa accagctatt
     4561 tcaggtggaa tattgtacac cttaatacca agaatataaa tatttgcgga ttaaaaaaga
     4621 gatatttcca aactctcatt acattttgga aatatctctt tacttaatat cctcatccgg
     4681 cacaaactcc atgatgtcct ctatcttaca atcaagtatg gaacataatc tgttaaggat
     4741 taccgttttt acgaccatat tctttcgcaa tcgctgtaac tgtgctttat ctattccata
     4801 atctttaatt agtgcatact ggctaatatt tttcttcttg agtgtgatcc ataacctgtc
     4861 atatactatc attacaaaga cctcctcctt gtattctacg caagagtgtc ctataatgat
     4921 atggtgcgtg tatgcaccat actgtatgta tatgatagaa tagaaaatag ccataatctg
     4981 catagaaaac agctctcaag gttattatgt aatatagaac ggattatctg ttttactttt
     5041 atggtattca accgggacaa ttcaagcacc tgacaatttg accgcaaata cccttctcag
     5101 aaaggattca caacaacact atgaatgata aaaacacata ctctgttgat aaatatttgg
     5161 aaatcattgc cgaaaaagaa ggaatcacaa aagaagaagt ccaacaggaa attgggcggg
     5221 cagtttccat tgctttaaaa agccctgatc caaaaatgca acgcttctgg acagactttc
     5281 catgtgaaaa tgatactccc accattgaag aaatcatata ccatctcgct gaaaaatttg
     5341 caaaagagtc atagacaaag gacaggataa ctacccgtct attcactcag ataatcttcc
     5401 tgtcctctta atatttgttc aatcatatgt aatgcaaatt ctatttctct ttcgtcacat
     5461 cgattcatca taaatgcaaa acgctcaatg tgtttttctg ggtgctgctg gctcatcaaa
     5521 accataggcg atgactccaa tgcatgaaca atattcaaat atgtatcaag actcattgcc
     5581 cttctgccat tttcaacact tttgatagta tccaatgata catctgcccg ttctgcaagc
     5641 tctgcctgtg taattccaag ccttctgcgt tcttttctga tattctctgc aataatttcg
     5701 tatatgtgct ctcttttccc catagcccca tcatcctttc tgacttatcg cattatatca
     5761 gaaattatta tgggttttag gaaactgtaa tcctttgaca ttttcgtgta atactttgca
     5821 tattccttct aaacaccaat ctacttttac actgaaattt aaaatttcag caaaatgtat
     5881 ataacaacat gagaaaagcc cgtggcagat ccacgagctt tatctccagt ttgaagcatg
     5941 gatatagata gttccctgct tttatttagt gtaacataca cctttactta gctacatgtg
     6001 taaaatccca gtgcgaaaat acgtctacat agcaggtttt tgtttcaacc acatatctct
     6061 ccatgccgcc taatgcttca ttatatcttt ctttatattt tgtctcaacg accttatatg
     6121 tataatacat aggacgatat ttgattaaat aatgagatcc ttttggaaca gttacggagt
     6181 atccgctacc taaagaatat gattttgatg cacctagtgt aacacccaac tcacttccta
     6241 tagttccacc atttgtatat ccaccggaaa ctgaagcttt aaaggaaata ttataagaag
     6301 tatcttgagt gtaattcaat gataattttg cgctagatgt agaactacca ccactcgtgc
     6361 catttctcca tgcaccactt tttaaactac ctttggtata ttgataacca tatacggtaa
     6421 caaaatcaga aatgcgttct tcattttcct catcagcttt aatttccgtt tcaaaataat
     6481 cagctccatc atgaggcaaa ttttcagtgt catagttatg agtctccgca gcaaacgctg
     6541 ttgtcgagca ccccaaaatc aatataaaac ttaaaaccat actaattatt tttttcatta
     6601 gaagtcaccc ccgctttgct ttaaaaaaac tataaaccag ataaataatt gccaaaatga
     6661 tactaaaaac aaaaaagcca ccaatataaa taagaggact tttaaaaaga taatccatgt
     6721 tattggtaag atatccattt cctgaactaa atccagttat tgagtcaata tattggacaa
     6781 taatggaaag aaacggaagc gtacttaaac caaatatgcc aaaaattatc attattatag
     6841 ctaaaatctt caaatgaaaa tctttcatca aaatcacccc ctattttaat atcattttgt
     6901 cgttatatgc agatcattct ataagcatat tcataattat atttacttct cctttcctca
     6961 gtattcaatg tgccatatag agcaatctgt tgtatattct aagaatagca ggaatcaaag
     7021 caaaagaaaa tatcctatgc agaaagtgac ctgtttttgc agaaaatgac caacagaaca
     7081 aaaattactc agaaatcaag taaaaaacac agcattgata ctatttcaaa gctacagttc
     7141 tgctctaaag aatatattga gagtacgctt tcaacaatat ttcctagtct aaaaacggta
     7201 ttagaagaat tttggtaaaa atttagcagg caataatttg aatattattg cctgccaaat
     7261 taatgatgaa atcatatgat tcttctgtca atcagaacca atctgctttc tcctatcgga
     7321 gtccaagcat acacactctt gcaatataac gtatcatcag ctccgagcct gtgctttctg
     7381 tatattgtct gaccaatact tattgctgaa aaaattccca tttctaggca aatttctgaa
     7441 catatccata acaatatcat atgataagcc tgatgtgtcc acaaacatct ctttcccatc
     7501 tttagattta actgcaattc cgttatcacc cacatacgct actgtattgt catctaattt
     7561 ctgtattaat cccgtcattt ccgcaaattt ctttagcgca aactccccgg attcttcaca
     7621 aagttttcgg aacttttctg catcctcacc taccatatac ggatattttc catctctaat
     7681 ataccatgaa attcccgttt ctgaatccgt gtatttagga tcagttaatg cccactcttc
     7741 caaaggaaca ccctgatacc atactgtcat tttttcactg gaatcattgc ttatttctgg
     7801 ttcatcattt tgaatttctt tctcagcaat ttcatcctgc ccctgttcat atcctctaca
     7861 tgacacgtta cactttagtg cctcataaat ttcttgaaca tttgcatatt tgttaactgc
     7921 tgcaacatcc ggtgtctcta acacttcctt ttgttgaaaa gcctttgatt ggttatattt
     7981 tgaacctgat tttcttcctg cgtaaatatt gttatttaca gcggtattta ccatatttac
     8041 catatttata atccctccag cagcaatata atctaatttt cttattatag tatgttgcac
     8101 tttatgccag attgctataa aatgcaacat acaatgaaaa tattctgttg cgcttgctta
     8161 atatcccata ttcaagcagc tattattgtg cataagcagc agaagcaata tagcctacct
     8221 gcgaagaccc aacagaatac aactcataat ggaaatggta tctaacgcct accttaacac
     8281 ctgtaaatgt cagtgtccat gaatctcctg aatagttagc aatttgtacc ggtgcacttg
     8341 ttccgtcatt tcctacaaga gtaattgttc cctgaagata atctgttcca ctttcattag
     8401 gcatataaac atttaagcac aactttgtaa cgcttgagtt attaatggtg taataataat
     8461 ttccgttgaa tacaccgctt ctggaattgc ttcttgtaat ggttctattt gcatcatact
     8521 gaatcgtatc tgcaagagca acggcgtcat cataagcagg tactacgtcc aaatcgccac
     8581 aatcgcttac ttctactgcc ttatttgcat taggggcagc ctgtccctga gtggatactt
     8641 cacttgcaaa cgcagttgtt cccattgcca aacataacat caaactcaac accaacgcct
     8701 ttaaactttt tactttcttc attttaaaat ctcctttcaa attaacatcg tataaatttt
     8761 cattccaaca ggaatctata aacaacttta tgcttttttc tgtctttcca gatttagata
     8821 agtattcata tttcgcatat aaaacatctg caaatcatac tttcctaatt tgttcatatc
     8881 ctgaataacc ttttcaaagc tggatataag gtcacatctt tcatttaatc ccatgtgacc
     8941 agtttcttgt ggaaaagagc tgagactatt acccctatca acatcataat atgcctccaa
     9001 agcactcatt tcgacataag aagcatttct caaatcaata tcgttaatat taatcttttc
     9061 ttcaaattct tttccatttt catcaatccc tttggctatc actacaggat tatcatctgt
     9121 tgactcttct gcatacttaa tataaaacga aagaccggtt ccatttccgc ctgaaaacaa
     9181 catatcatcc gtctttaaat acactttcat tgatgtctga ggaaatgcct catttccgtt
     9241 aacagatgtt ttgctattgt tttgtcgctt tccaaataat tcagatacac tctgcactcc
     9301 cgaaccaata cgcatttaac cacctccatt cgcattataa tatgttattt atatgaatta
     9361 acatatatta gtttgcacta aacgtgaata ccgttgaaaa ggaacgtgta gtattaggga
     9421 agtttgttga cctgaaagtt gtattaaatc tataacttcc cgcttgcgta atcggaccac
     9481 aatcatatgt ataatagaag ccatctgcgc ctgtaccaga tataataaat ggctcctgat
     9541 gtatccacga aatacttctt ccatcaaatg ttgtagtatc gctgccatat ccatatacct
     9601 tgatcgtaac gccaaaattt ccatttgtaa gccagccata tttataaagt gaaatgcttg
     9661 tcacctgcgg agccggtcca tctccaggcc accatagcgg attaatccct tcctcattac
     9721 cactgccttc aactattgtt ccttcctgat ctcctgcaat attcaccgtc attccaccat
     9781 cattggtttc agaatattca ggaatactac tctccttttc tgctgctgac accattgttc
     9841 ccatacccat taacatagtc aatgctaatg caaatgcaat aactttctta atttttttaa
     9901 catatcagta cctccttttt atacttgtca tcttggaata aacaattaag ttcctatagc
     9961 atctatggct acagatataa tagtaaaaca cgccagttaa ctatctttca cttttcttct
    10021 ggataatcgg acgtttcggc tgatgaaata ttcccatgca tgcaggtggg aatctatcta
    10081 ttccatatac agcttcattt ctcatgacat gttctacaac cttcaacact ttcttattaa
    10141 ccttcttcat tctttcacct cctgtttaaa aatttttgct atacacagca aagctgcaca
    10201 taatataaca gctattgcca tataactaac gtaaaccata tctgcatcta acagaacaca
    10261 gccaagtatt atgcacccct caagtaaaac aatagtcctc gcagattttt tcgattccat
    10321 caattcatct gatgtcatgt gcatattagg atgattcgct gtaccaatca atcctatccc
    10381 tgttatagca agtagtacta ttgcaaataa ccattgtgga tgttctgaca atttttcact
    10441 tataatcacg ataactaaat aagaaacaat ggatgctaaa taacatctat aaaacttgtc
    10501 cagatgatat ccgccagttc tctttcttaa ttctaaaaaa aacacaagaa aaaatatagt
    10561 tgggagcagc ttgtgaaaca tcaaactgat tacgataata ctgccaacag taataaattt
    10621 ctctatccaa cagataaaaa cataaacata tcttgcttcc atctctttgt caattaacct
    10681 tgcttcagtc atctgaccaa ttaaatcatc agctattttt tcaatcatag ttatgcctcc
    10741 tgccaaatta agtataactt tatctgttta caaaacaata tccattgcag aaagtgacct
    10801 ttttttgcag aaaatgacaa aaaaaagtga tttgcttgca gcaaatcact tttttaaggt
    10861 tcatcttagt ttggcaatat aactgagaag tagaactcat tattatcatt tcgtatagca
    10921 taagagcctt gatattttgt tataacctca attatatttt ttattccaac cccatgctca
    10981 tccatttcat atttctttga ggtctgtatt tctccatctt taatattaag tttaccatca
    11041 tatgtattct ttacagatat aataatgttg tctttctctt taaccagttt cattttcata
    11101 aattttttgc ctgagcactt ttcacaagcc tctattgcat tattcaaaag attcgataat
    11161 ataacaacaa tatcctcatc acacatttta attcctgata gatcattgat ttgaaagata
    11221 aatacaatgc ctttatccaa tgtttcctta tatttgctat ttaatatagc atcaataatc
    11281 acattatttg ttttaatata atctaactct gtactcaaat ttccgcttat acttttcaca
    11341 taatccttta gttcatcata attttccatc tctatcaaag actcaatgca cataatctgg
    11401 ttcttatatt catgtgtttt tttccgttgt ttaacaaaat tttctgaaat agaacggtac
    11461 atgtctgtct gatttcgtgc tttcagttga aacacttcat tttcacgaat cttaatttca
    11521 cgttttaata tatcatttat catatagaac acaactatat tcatccctgc taaacacaat
    11581 gctataacca agaatacatt ttcctgcttt tgattctcaa tgtttccaga tgtcatgatc
    11641 aatgcaataa ctgtgaagat tgtaaaaact gggaaaaaaa taaatcgaag ccaatctgta
    11701 cttcttaaaa catccgagga ctcccctcct actttcttcc tgataagcaa aacaactagg
    11761 aaaagaatta tttttcccaa aaccgttatt aaacttccac ctacaaaatg caacctgcta
    11821 atttctgcta tactatcaaa aagagaaaca tttaaccata gtgtaaaata gtctacagaa
    11881 agcagcaatg cctgaaataa taatgataag attattgctt ttccgaaatg aattttaaaa
    11941 taaaagcaca taaacaccgc aacagcaact atagccaata tttgtttcaa gataaactta
    12001 tcataaaata atgaagctat tacatattca cataccacaa ttcctaaaat aatactataa
    12061 tttctataat tattttttga tctcttttca gcaaaacttt caaaaaatat tttgcagcat
    12121 attacctcca atattatcat cataatactt tgaatgtaac taatcagcat ctacaattct
    12181 cctttatacg aaacaaatgt ttcttcaaca aatttatatc gtgcttttgg aatttccaac
    12241 ttaataccat tgttcaataa cgcctcatac cggctgactt tctcaatatg cttcatatta
    12301 accagataac tttgatgtat ccggataaaa tcattacctt gcaactcttt ttccagctca
    12361 tctagtttgc catatattga atattttttt aacttgtcct ccataatgta aaactcaagt
    12421 ttatgcaatc tgctctctat gtataataaa cgctctaatg ctacaatctt tgtaccctca
    12481 ttaaagttaa atttcttctt ttgggctaca taattcatat tcaagctgat tgcatccata
    12541 cactcaaata ttagttccgg aaaatttaca ttatttttca aaatatatct tatagctcct
    12601 acgctgtatc cttgaggggc acatgtaata aatgctgtaa caaaaactat aaaaacatca
    12661 ttgctgactt ttcttatttt ctgcgcagtt tccattccat ccagttcatc catatttaca
    12721 tccaaaaaaa caatatcata ctttgccaga ttgataccta aacttataaa atcctttcct
    12781 gattcaaatt catcaatttc gtataatata tcattttcat tcatatattc tattaaaata
    12841 tcatgaatgc gttttctaaa ttgtctttca tcatcacata tagcaattct gaacatatgc
    12901 tcatcccctt ccacacacaa atttgacata cttctttcat ttggttggat tattttttgt
    12961 atattttcct attttttatt atatttcggc atctttatcc aaaattttaa ccattactct
    13021 atattgctaa tatcccatgt tcgtctacaa aattatatat caatacctat ttttaataca
    13081 ttttgctatt gcacatatcg tttcactgca atctttccca taaccataaa tactgctatc
    13141 aggactatac ttacataccc ggcataaaaa taatcttgca gatccagaca aaacaaaatg
    13201 ataagaacac atacctgcaa tgccgttatg caatgtgtta cccttgcata ataccttctt
    13261 tcttcctcat caagcggttt attgatactt tccactgggg caaggacaat aataattacc
    13321 acggcaagaa ctccgatcaa taaaatcaag gcattaggaa catttttcat tacaggctca
    13381 tatgtataaa ccggaataaa taaaattgcc attgaaatca aaaaacagcc gattctactc
    13441 ttacagtggc tgcccccact atagcttctc aacgaggcat aaaataacag gaagaccaga
    13501 acaagtcccg gtctccccgt cacaatgcca aatattccag aagccaaaag gtttcctgca
    13561 acaacaatac cattttctat cccatattgg tacagttctg cctcctcttt ttgcacaatc
    13621 cccttttgta tcaatatttc atttatcttc tttgcaaatt tagcaatcat accctgttac
    13681 caccttaaaa ttttctaagt tttttcgcat tatccggtaa cttgtcctgt ccgaaaataa
    13741 accagcagca acggttcata tttgttgcag ttaccgtaag ggcaagtgct gccacgctgc
    13801 ttaatgctcc atgactgagt cggttcatca atcttcttaa ttttgacata tatgtatgtc
    13861 ctccttttca tttgatgaat gcactatatc atactttaca ggaaaatccg tcaaagtgta
    13921 acagattgac atttaagtgt aacactttgc atttattccc tcacttcaat tccatagagc
    13981 attgctgaaa cctcaaatat atccccttta tctgtaaaac tgaccgttcc attgtatttt
    14041 tctatcactt tgcggacact ctgaacacca tgcccatgtc tgatattatc tttcttggtt
    14101 gttttcaggc ttttattttt ctttcctgtt ttgctgtttg ttattacaag aagcaaaatc
    14161 cccgactggt acttattttc aatctttaca aaacgctgtc cctccggcac cttgctacag
    14221 gcttctaccg cattatccac aagatttcca tacaatacac ctatatcccc gtgatcaagc
    14281 tgcatctgct ttggaatacg aatagatgtt tctactttta ttcccctcgc ctttgccctg
    14341 ccaaatttaa tgcggagcac agaatctacg attggattat cagaatactg cttttcatct
    14401 atctgctcaa attccttgca catcgcaccg attttctctg aaagttcctg cccatcacta
    14461 ttttccacca gataatacag ttcatgcaat ttatgtttca tatcgtgctt taacttctgc
    14521 acttccttat tctgtttttc tgcttcttca taatagatgt ctttatagtg catttcttcc
    14581 ctgtacattg catcctcata ctgtttttgc acaagataat taaagcgttc catcatatac
    14641 agcataaaat aatctgtcag gacaatggaa attacaatac tggcacacat aagcaggctt
    14701 ttttcactgc cagcttccaa tgacaaaaga ataacaaagc aacagttcaa caccgtaaag
    14761 gcaaatacca taacaagcac acccaaaatt tctttcggaa aatcagcaat ctgcatccct
    14821 ttctttgaaa tcaattttga cagaatatac atcacatttc cacgaacaaa gctgcatatt
    14881 accattacaa aataatattt ataactttct cccatgcttc atactctgga tcattcttca
    14941 ttgcttcaaa acccgcctct gaaattgtaa cagatattga ctcgcctgct cttgtggggt
    15001 gcattggaat ttgagatatt ttattgtaaa tgtactgctt gtattccacc atcgtcatat
    15061 ctttagcaga cacagaacct atttttgaat tgcccactat acttccacta gcttcgctct
    15121 tttctcttac actatccgca aaccttgtat cttccttctc ctgatcttta gccgcatttt
    15181 tctgctggta ctgattgtaa gcccgtgtca tatagttcac attaattgta ttactcatag
    15241 taacctcctc caaatatatt tatataattt aacccgttgt gctagttgat tgttgatata
    15301 gaaaaacttc aacaaaatat gctatgcatg gcatttaaca gtatattccg ggcatcctgt
    15361 gacattggaa aaatcaagca gctaattttc tgaaattttt aacttttaaa aataggaagg
    15421 gatttttcgg gcttttttag tatatttcac caactatgca gtttaaataa aacaagtagc
    15481 acaacgagtt aatttaccta aacatggtaa ttacatatct gccaattact ttttgactgt
    15541 tttttcttcg tataattttg caatatcttc tttgtgttga aatatatctt tcagacgcaa
    15601 gctttccata tactcatcgt cagccttttc ttgatattgg cgttttttta atctctctcc
    15661 caaagttcat ttaattcatc ttttttacac tttttcgaat aaaaactgtc tttatctttg
    15721 gaatgtgcat caaacgctct tcctgcctct tttgtatgat cctgcatata ggaataacct
    15781 ttatatccat tttcatcaat gtttattaaa gttccaccac acatcatatt tgagccatgg
    15841 gcatcctctc tgatgatgtt catcattttg tttttaaact ctttgtccac catcattttt
    15901 tcaaatgcac tattcgttat ttgtaccgaa atattcgatc cccacgacat agaatctatt
    15961 tctttccaaa tctctttttt aaaattttcc aatttttctg actctgataa cccctgtgtt
    16021 tgattaacat ctgttgcacc tgatgtagtt ctttttgtaa aatcttttgt ttgaacagaa
    16081 aaattacctc ctaatataga atcaacaccc atgcaattac ctccttgata taattctata
    16141 ttgtttattt caatgatagc tcctctagcg ttcagagtag cccttgttcc ctttgcgttt
    16201 tctccatact cctttttcag tcgtgccagt tcatcattat agatagatgt aaatacacgt
    16261 gcccttgcaa attcttcctc tgtgcttatg gctttccagt tccttgattc aggattgtaa
    16321 gacagcgttt tatttccatt gttgtcccaa aacatacaag ccgcattcat ctttcctcct
    16381 gtctttctca tgcttgattc atagatggtt tttctgtccg gggaaactgt ctcaccatgc
    16441 tgcatacata attttcgata tgccgcatca tcccgcttcc cggtggcaaa ttccttctgt
    16501 gcaagttcct ttatagcttt ctcgaattct tcctccgaca ttgcaggctt atcacgtttc
    16561 gtcataatat tatcccaatt cggttttgtg aattgaatat caaccggctt gaaacgcagt
    16621 gcgaaatttc cataatcaca ttgttacacc atttacaata aatttgcgta tattctctcc
    16681 atcgactaag cggagaaaca ctgttcacaa taatttccat tactctattt ttcactatgc
    16741 tttgacatca aaactgcttt tcaaattttc ttcatttacg gattcccctc ctactatcgg
    16801 aagtcctctt tttgcatttc cccatgcttc attataaatc atgcacattt ctgtttgcct
    16861 cgctgcctct gcattcgtgg tatacattgt ccatccattg ttggaataag ttgctaccat
    16921 ctccccattc ttatcataaa attctatgta ctcactattg cccgatggca gtttctgata
    16981 ctttactttc ccctcaagca gagttgcgac aaaatctatc ggctttaaca cattatgtct
    17041 atttcttgaa acagctttta atccagaagt aatgattccc tttctatccg gggatacttc
    17101 tgatgtataa tttttcatca atttgttaaa gccatctgat ttattttgaa atgtaccctt
    17161 ttcaaaatct ttataagcct gcgctacaat ctgttttctg tattcttcat cactaatacc
    17221 gcttttcttt ttggaaaaca catacttatc gttaaaatcg ggcagatgga caccgcctat
    17281 acttcctgtt cctgaaaaaa tcctttgttg taatgaacca ttggacgaat taacctgcat
    17341 tattccaccc tctcctgtaa atttcctaat ttattcagca tctcatacat ccggctacta
    17401 cctaacatat aattttgcaa aacaagaaac ttacctgtct gtttgctttc ttgatataac
    17461 ttgatgtagg catccttcgc ctgataaaag ctgtcctcca attcttcaat ctcttttgtt
    17521 ggcacttcag gaatattccc ctgaaagacc tgtccccggg ctgctattct ggcacaggat
    17581 ttctgccatg ccacttcctg ctcatattgc atatccagcc actcaatttc ttctttcgtc
    17641 catggtgtac cacctgctga cttataatac tgctcatttc catttttata acgttcctca
    17701 atttcagaat aaagccttgc ataactcaat ccgcaggcat ttacaacatc agtatagtca
    17761 tactgccctt tttcttccct aatttctttt aatattccgg ctctcatatc gctgaacgat
    17821 gtaaccgaat gcacaactgt atgcttaatt ttatccatta aattttccct gtttttcgat
    17881 aattgagaaa cctctaaagt atccttatga aacactttct ggtcttcatt ttggctttcc
    17941 tgttttccca aatattccct atcaaacttg aaaaaatccg gcagatgaat aggattactt
    18001 aaaaatgtaa ttgacatatc tctttctcct tacttaaaat cactatccaa gcgaaaaagc
    18061 actatccgta accgcttccg tcatagcatt tgcttcataa gcattagacg cttttgacaa
    18121 cagcctttca ttgttccacg accgtaataa tcggcttctt tcctgttcct gctttgcaat
    18181 cttttcattc aacatttcct gctgctgttt tttaacctgc gcccgttttt ctagatattc
    18241 ttccaaaagc tctttttgtc tatctttctt gttgcttgtc tttttataaa aactgttttg
    18301 tgaacgagca aaaaattccg attgattatt aacaccagac catgaatcgc ccctataatc
    18361 tttagcagta gctcctacag tgagcaccat agaagcttcc aacggtgcaa aggacgaagt
    18421 taagtcacgt ttaagtgctg ataatatctt ttccctgtac tccggatcat ctttcatatt
    18481 cttaaatgct tcctctgata tgttgatagc cacattggtt atagttctat ttctgggtat
    18541 cttatcaatt tcagcataaa attccttttt gaaaatcgcc atttcttccg cttctgataa
    18601 ttcctttgta ttgcccgttt cttccgtgct gtttacgctc tttgtacttt tcgttgttgc
    18661 aacattgttc tgataataac tctgtcctac tccactaata gccattttta atcctccttt
    18721 atcagcactt tttcataata tccgatagta tgcttgttgc tgttccttgt ttgtaattta
    18781 tacttttaaa ggctaccaaa aacttctctt tagcctgctc cattattgat actgcggttt
    18841 tctgatattt tgtatcaaac atttgagcct tatcttgtgt ttttacttca ttttgagggc
    18901 tatttctacg gaaataccat gaactgtctg cgttttcaaa tgctttattg gtttgttgac
    18961 aggtaatata tccttctaaa tttgccagac gcattttaaa ggcttcgtcc aatccggcta
    19021 aatcttcgtc aagtgtcaat gaccttttcc ccgtaagttc gtaggaaact tcacgatctc
    19081 cattttcatg ttcttttacg atttcattat aacgggtttc atatgtatcc attatagatt
    19141 tcatcacatc ttcaacatta taattcccgt cttttaatgt taggctgcta atatcccgca
    19201 ttgcggtata gtgttcccaa gcaacctcat ttgtattttg tattgtcagt tccctgacat
    19261 tggtataatc cgaatcgggt tcaaatttgc ttgccatttc ccgcagcata tttcttcctg
    19321 catcagaaat agaaagattt gccgactgct tcaccatctt tgagattgct tccctaacag
    19381 ttgcttttcc ccgtatataa tttgtagtcg ttcccaaata atcataatta tgtccgactc
    19441 cattaatagc catttcctaa ttctccattg tcatcaattt tttatattgc cgcccctgcc
    19501 cccttgcaat aagtccgggc agtccgcaaa agcaaaggtt tatgcgcctt gcggaatatg
    19561 aacaatttct ccttatgcct ttatatcaaa acttgcccct gtcggcgcag atgtaccaga
    19621 aaccgcagct aagaggttct gcgtaacact ttttacatca gtgccagtag ctgatattgt
    19681 aaacgtttca tcttctgtca gcttctccaa ctgcgccttt ttctctgccc gtctcttagc
    19741 tgccttttct tctgagattt ttctttcctc acgctttttc tataatcttt ctttttcttt
    19801 cttttccgca ttcaatgtag ttgaattttg ttttgaacca ctggttcttg tcatacctcc
    19861 gcaagtaaca gaagcattcc catcggcatc tattacagtt gtaacaccat gtatcactgc
    19921 attatcagct ttggcttgtg caagcattct attctgtccc ggtactgcac cagttaaatt
    19981 aaactctact ttcttggcaa attccggatc atttgccatt ttctttagac attcgctaga
    20041 aagatttatt accactttat tttcatttcc actcataaga ctgctacccg tattaaaagt
    20101 aatctccggg aactttttac acagtttctc ataatattcc tgcactttgt ccttgctgtt
    20161 tgtctttacc tccgttgcta cattagtgtt tcacactctt ctacttcgag aattaattgc
    20221 tttttcatat cctgtcataa aactcgctat attaaacaat tccaccgtgc ttatattgct
    20281 gttcccgaag cttatccaac gattttgctc catccgggct atacaaatcc aataattcca
    20341 aaaaattacc agactcctta cacccattca atatcatacg catactatcc gcatctttac
    20401 cgaataacat acccaacaga ctcatatcat actgattttg actatcactt aatactccct
    20461 gctgatgtaa atcctccata aaaccataag aacgaacctc ggaacctatt cgcatcgcca
    20521 cattatataa atccggatca acagtatgaa gataatttag gtagcgtgtc tcaatatttc
    20581 tattgggcgt gccgctcatc atccaatttg ctatatcttc caaagatgca cctatggcag
    20641 catcatcaat caaatgcatc tgccatcttc cgctttcagt ctttgtaaag gtatattttc
    20701 catcttccga atacaatgta tttgaccatg agttttttgg agccgcctgg tctctgacaa
    20761 gcacttcaaa tgcatccatt gcaactctgt ctgggataca ctttttctca tctgttggta
    20821 attccatttt ccccaatgct actgcagttt gcactagttc ataatccgat atgttttctc
    20881 catgataaaa ataagaattt tgttctttca atttatcaaa tgatgccggt agttttactt
    20941 ctgccaactg ttctttggaa acctcagtcc aatcttcttt tttcttacta cctgcggtct
    21001 gcatctgcac tctcggaccg tttgtaatct ttgtaccata ttttgcattt accatatgtt
    21061 ctgttattgt cacatgtgca aactgaaata aactcctttg gtttcttgta tttccgtaac
    21121 cttcaacttt cacagcatat ggaaatgatg acttcgtatt caaaacagag taagtacctg
    21181 tataaaatgt atttgccgct tgtattctca taatataacc tccaatccaa acagaaacag
    21241 cgtctatttt cacattcaat cccttgaaaa cagacgccat ccttagctca taatatttat
    21301 cgacattcat tcatttttct ttacagaatg gaacgaaacc tgaaatttgg gcgtgcctct
    21361 tactatatct gtaaccctat aagttttcga tactcctttg cattttcaca atctgataca
    21421 attcctgatt gcgcatccaa gcaaaacggt aacatctgcc aatcctcatt gccacatgct
    21481 cctaccaata acaattgttc taaataagta ttaaaatctt tacccagtat atatccatgt
    21541 ccttcaccat cgtcatggct aagatatacc acagacggat ttatttcact ctctttcata
    21601 tcaaatgcta ttgcatcacc attagggaca ttcataaaac ccaattttgt gtttcccatt
    21661 tgacttataa atatttgctt gcttctctga tactcaattt atccatcttg tctttatgag
    21721 tttcaacaaa atttcttacc caatcctgat ttgtcttaga ataatctctc agactccaac
    21781 cgatggcttt gttgataaag aactctgaac tgccaaagtt attcactaat attttttcaa
    21841 gcaattccgt atttgttcgc tctttcctac aaagctggtg gtcaatagca attcggcgca
    21901 cccaaaaatc ttcatctgtt gaccactcca acattaggtc atttattcgt tcatctgtaa
    21961 aagctataat ctatgccgag ataccccatc acatcggata caccttctgt ccatctggca
    22021 tactcctcct gagaatatgc tactgtgtgc atattcccac aagcattccg caacagcgta
    22081 gacagcgaac ccgccatctt ctgcgctttc atatatgcct ctgtatcata aggatcatta
    22141 ccgccggaaa cctccacacc ctgttgcttt accttcaata tgtaaccgtc gtttacagcg
    22201 atgcgcatgt cggatgcaat attgacggaa ttgctcagcc tgtttagaga agaactatct
    22261 accagcttaa tcggcgtttt gagcacctat accaaatcct ctatgggatt taacagattc
    22321 tgcatcgaac cattgaatac ctccctgtcc tttattgctg tatttttcac atttgatgtg
    22381 aattgtctgg tattcggatt gatataataa gattgattat ttgaaatttc cattgttttc
    22441 tcctttggtt atgttcttca caagctctgc ttccatcata atatttgcat cataagcatt
    22501 ggaagccttt gccatctgcc tctcactgtt ccatgactga gtctgtctac ttctttccag
    22561 ttccatcttt gcaatttttt tatttaacat ttccagctgc tgtttcttag cctgcgcccg
    22621 cttttccaaa tattcttcca gcagttcctt ctgccttgcc tttttctgcc gtccggcatc
    22681 agttcccttt gcggaggaac tcccggaata accgtcattc tccttcatgc cctgcgtata
    22741 gccgtaacat ttctcatatg tgtcatctat atgcatatat gatatttgtg gaatatagtt
    22801 tccaaaatta actgccttat tcttcgctaa agcgtctaat attttcttct catattccgg
    22861 atcagtctgc attcttttat aagcggcatc cgtaatatct ataatatcat ttctattccg
    22921 ctgcgatgga tgtgtatata atgaattcat cttttcatta aaatactcct tgtattcctc
    22981 caaggtcata tcttccgagg aaacctgact tttgtctgtg accttttccg cagatcccgc
    23041 ttgtttttcc tccttcctca aacccatgta actctttgct gtttcataat aactgccata
    23101 aactgaacct acatccatta ctacattctc cttccttttt catatttttt tattttattt
    23161 ccttctgctg cagcattact gtgactttaa acacatcgtt ttttattttg atatccatat
    23221 ctccaagata atggtctgcc acatccttta cattttttaa ccctattcca tgctccatca
    23281 aaatatccgg cagatcgctc tgtttcgttg tcatcgggac gatacctcca tcttcccata
    23341 tcactttccc atcaaagctg ttttccactt caatcagtag gaaatgattc tttttcttta
    23401 aagtcagatt gatatatcgc tgttcctgct ccagtttctc gcaggcttct atggcattgt
    23461 ctaaaaggtt attcagaatg atacctatat caaatgcaga aattgtgtct gtttccccca
    23521 agttaaattt tacttgaaac gaaatacctg cattttccgc tttctggtat ttatcattga
    23581 taatcacatc tgtgaccgca tttcctgtat tgaatttata gtccatagtc tgtatggttt
    23641 catccagctt ttcgatataa ctctctactt catcatattt ctcacttgcc accagccctt
    23701 ttatattcgt catatggttt ttcatctcat gccttactct gcgaatgctc ccgtagaagt
    23761 tctctgcttc ttccagtctc tgcttcatgg ctttgacctg ttgttcttcc acaaaatgtt
    23821 tctgccgttc tttttgaagc tccctgtaa
//
