LOCUS       c00001_NZ_JAJF..       20570 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJFOJ010000001.1 Roseburia inulinivorans DSM 16841 strain
            FDAARGOS_1587 ctg.s1.000000F_arrow_pilon, whole genome shotgun
            sequence.
ACCESSION   c00001_NZ_JAJF..
VERSION     c00001_NZ_JAJF..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:59:55
            Original ID  :: NZ_JAJFOJ010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2689330
            Orig. end    :: 2709900
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20570
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2699330:2699900](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10570)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20570
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20570
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="6"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             687..1313
                     /locus_tag="ctg1_2467"
                     /transl_table=11
                     /translation="LELFAGTRSIGKAFESRGHEVFSVEWSKDFENIDLYEDINKVTAE
                     DIIRLFGKPDVIWASPDCSTFSIAAISHHRRKNPDTGSLEPVSTYAKFCDMVDQHVLKL
                     IEELQPRYYFIENPRGGMRKMEWMKGLSRYTVTYCQYGDNRMKPTDIWTNHPDPKFLPM
                     CHNGDSCHVAAPRGSKTGTQGLKGARERSVIPQKLCEHIVDICEE"
     CDS             1333..1737
                     /locus_tag="ctg1_2468"
                     /transl_table=11
                     /translation="VASEGKVRRGFYIEEDLLEQVDGLLEQADVKSRNEFLNQALKFYI
                     GYLTSEKIENYMLSTISSVMHSTVKDSENRMARAMYKLAVETSKLSHVIAYSHGVDEEA
                     LRKLQAKCAEEVKRINGTVSFESAYEYQKG"
     CDS             1864..3081
                     /locus_tag="ctg1_2469"
                     /transl_table=11
                     /translation="MSNVRWESPFPYSLAFNLFKQHFEEINRSYWAFVPAANTIKSFAK
                     KSLLDDNADPKKFFLIPDEEDRRMAPTYGEWKTDFSEYVNYSRLNIIMLLSSCFETYLR
                     TVVSLSFESKPGVIINCQDAVDGAALLKRDIMYGNMNDKSYRFGEVIEEVCRGEWANRF
                     CAFQKYFGKLPPQLLDLSKDLDELRVTRNNLGHYFGRRKDVYSAPIDFEPIETTRISHE
                     RILKYFKLIYSAAKMIDGYLHKNIIGSYDIIKKYFFSLSNGEILTDPYNPDAYQLRKLL
                     GRHDLTRVGKKYYDELVTYCETNYVESETDCIFTRKRCVKEINRRLKESGTKLLYNGQV
                     VPFDPLSFKLLLIKDNLYDKDNYSERKIGNNRQVQYLHSLALIDYVTKKLESNSNSIME
                     KLKEEK"
     PFAM_domain     2788..3069
                     /aSDomain="EC042_2821"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18740.3"
                     /description="EC042_2821-lke REase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2469_0125"
                     /evalue="4.60E-08"
                     /label="ctg1_2469"
                     /locus_tag="ctg1_2469"
                     /protein_end="402"
                     /protein_start="308"
                     /score="33.2"
                     /tool="antismash"
                     /translation="ETDCIFTRKRCVKEINRRLKESGTKLLYNGQVVPFDPLSFKLLLI
                     KDNLYDKDNYSERKIGNNRQVQYLHSLALIDYVTKKLESNSNSIMEKLK"
     PFAM_domain     3084..4259
                     /aSDomain="MobL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18555.3"
                     /description="MobL relaxases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0126"
                     /evalue="3.70E-36"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="392"
                     /protein_start="0"
                     /score="125.1"
                     /tool="antismash"
                     /translation="MPKLILRCNYLKNAPPSHLANYMNYISTREGVEKIDNTCGLLPAT
                     VKQKELIADILSKIEDADRMHEYYDYLQRPTRENATEFITQALENNLDIIAKKKNYIDY
                     LANRPRVEKIGTHGLFSNEGESIVLSRVAEEVANHPGVIWTNVISLRREDAERFGYDSA
                     AQWQALLRSRVELLCENYKIDSRNLKWYAAFHNESHHPHVHLVVYSTNPSEGYLSPKGI
                     DTMRSTYAHDIFRQEFMSIYEKRTQQREQLKEQANKSLLFLVQQMQSGICHHEKIAEQM
                     KVLSKRLMNTSGKKVYGYLKADVKAIVNGIVDELAKEEKVAECYKQWLESKSEILHYYK
                     DADAEQLPLSEQKELKSIKNMVIREAVRYGEGYLYTEDEGLEDLETEREEMD"
     CDS             3084..5864
                     /gene_functions="other (smcogs) SMCOG1295:Sel1 domain
                     protein repeat-containing protein (Score: 108.6; E-value:
                     8e-33)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2470"
                     /transl_table=11
                     /translation="MPKLILRCNYLKNAPPSHLANYMNYISTREGVEKIDNTCGLLPAT
                     VKQKELIADILSKIEDADRMHEYYDYLQRPTRENATEFITQALENNLDIIAKKKNYIDY
                     LANRPRVEKIGTHGLFSNEGESIVLSRVAEEVANHPGVIWTNVISLRREDAERFGYDSA
                     AQWQALLRSRVELLCENYKIDSRNLKWYAAFHNESHHPHVHLVVYSTNPSEGYLSPKGI
                     DTMRSTYAHDIFRQEFMSIYEKRTQQREQLKEQANKSLLFLVQQMQSGICHHEKIAEQM
                     KVLSKRLMNTSGKKVYGYLKADVKAIVNGIVDELAKEEKVAECYKQWLESKSEILHYYK
                     DADAEQLPLSEQKELKSIKNMVIREAVRYGEGYLYTEDEGLEDLETEREEMDADDSEVS
                     EDMAEVLADYSDAEPETEEPDSQEFYAKWTDAYKEAREYLYGTSEMEPDEEAAYEIMKE
                     EAEQGNAYAMADMGKMYAQGIFVEADKAKAQEWYEKSLKAMLIVEGRKENTYLEYRIGK
                     MYQYGLGTEENLPEAAKWFGMASSKEHKYALYSLGMLYLHGKGVEQDEEKACQLFQRSH
                     KKGNPYASFELGKLYEAGRGSERNTDLAGKCYRVAFLGFLNLEKKSRDDTLWYRIGTMY
                     LQGVGTEADEKEAEKYLRKSADYGNTHAAYQLAKLYIRQETEKRKTNPEEIPDYEKIRQ
                     AFKWLTAASEQGNSFADYALGKLYADGELTAKDMEKAFYHLHRAADADNVYAWYKLGRL
                     YLSDEYKNIGRAVHYLKLAANQKNEFALYRLGKLYLAGEEVAKNVELAIRYLEESAGVG
                     NQYAQYVLGKVYMMEKEVEQDKEKAYEYFRLAAEQGNVYAVYFLEHWNDMPHPDLLLMA
                     TRLMHHLENILKDDVSGKKGDRRTGMDRKLARKIRQKKIAQGHARDDREEMVQTQ"
     PFAM_domain     4476..4568
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0127"
                     /evalue="1.40E-04"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="495"
                     /protein_start="464"
                     /score="22.6"
                     /tool="antismash"
                     /translation="AYAMADMGKMYAQGIFVEADKAKAQEWYEKS"
     PFAM_domain     4617..4712
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0128"
                     /evalue="4.80E-04"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="543"
                     /protein_start="511"
                     /score="20.8"
                     /tool="antismash"
                     /translation="EYRIGKMYQYGLGTEENLPEAAKWFGMASSKE"
     PFAM_domain     4719..4817
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0129"
                     /evalue="1.80E-05"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="578"
                     /protein_start="545"
                     /score="25.4"
                     /tool="antismash"
                     /translation="YALYSLGMLYLHGKGVEQDEEKACQLFQRSHKK"
     PFAM_domain     4968..5054
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0130"
                     /evalue="5.30E-04"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="657"
                     /protein_start="628"
                     /score="20.7"
                     /tool="antismash"
                     /translation="YRIGTMYLQGVGTEADEKEAEKYLRKSAD"
     PFAM_domain     5208..5312
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0131"
                     /evalue="2.70E-04"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="743"
                     /protein_start="708"
                     /score="21.6"
                     /tool="antismash"
                     /translation="FADYALGKLYADGELTAKDMEKAFYHLHRAADADN"
     PFAM_domain     5421..5510
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0132"
                     /evalue="5.90E-04"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="809"
                     /protein_start="779"
                     /score="20.6"
                     /tool="antismash"
                     /translation="ALYRLGKLYLAGEEVAKNVELAIRYLEESA"
     PFAM_domain     5526..5630
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2470_0133"
                     /evalue="8.50E-06"
                     /label="ctg1_2470"
                     /locus_tag="ctg1_2470"
                     /protein_end="849"
                     /protein_start="814"
                     /score="26.4"
                     /tool="antismash"
                     /translation="YAQYVLGKVYMMEKEVEQDKEKAYEYFRLAAEQGN"
     CDS             5877..7361
                     /locus_tag="ctg1_2471"
                     /transl_table=11
                     /translation="LGDFIYFTEEQKERANAVPIMDILKREHEEVERSGNEWRWKRHGS
                     VTFRGNRWYRHSQQMGSHAIDFMQEFFGMSYPEAVTYLLDGETGQVIHGGSPPRETTGK
                     KSVRPKEEKTTEEKEPKVLIPPEKNDTMKRVYAYLMQKRHISREVLSFFARQGTLYESA
                     GHHNAVFVGVDKEGNARHIHKKGTCSDGRSFRMNEDGSDSSYGFGYVGAGNKLYVFEAP
                     IDFLSFLTLYPVNWQENSYIVLNGVSEHAMLQMLKDYANLDTVVLCLDHDPAGIEACGR
                     LAEILVQNGYRQIKNLKSTCKDWNEDLKLLHGEEVIPAQEHPKILECDAWMEILKQVTD
                     SVDIKYATKENVCRYYQDIYNALKKGNGKEHLEDAFDGGGMLLTGVLVRCMEKTGRELG
                     RETSADEILDNLHKRYRPHRDKGNYNTRLRNMQKAFEELMEVFDKEDLSLKENKEEFVK
                     KSMSLTMECIKAHIFFATEYEEPIQRKEMRMECSQP"
     PFAM_domain     6285..6500
                     /aSDomain="DUF3991"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13154.8"
                     /description="Protein of unknown function (DUF3991)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2471_0134"
                     /evalue="1.40E-17"
                     /label="ctg1_2471"
                     /locus_tag="ctg1_2471"
                     /protein_end="208"
                     /protein_start="136"
                     /score="64.0"
                     /tool="antismash"
                     /translation="AYLMQKRHISREVLSFFARQGTLYESAGHHNAVFVGVDKEGNARH
                     IHKKGTCSDGRSFRMNEDGSDSSYGFG"
     PFAM_domain     6525..6800
                     /aSDomain="Toprim_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13155.8"
                     /description="Toprim-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2471_0135"
                     /evalue="1.80E-20"
                     /label="ctg1_2471"
                     /locus_tag="ctg1_2471"
                     /protein_end="308"
                     /protein_start="216"
                     /score="73.1"
                     /tool="antismash"
                     /translation="YVFEAPIDFLSFLTLYPVNWQENSYIVLNGVSEHAMLQMLKDYAN
                     LDTVVLCLDHDPAGIEACGRLAEILVQNGYRQIKNLKSTCKDWNEDL"
     CDS             7346..9142
                     /locus_tag="ctg1_2472"
                     /transl_table=11
                     /translation="MQPAVMLLVSGVIMFSVIEGLSLLAHYYTLNGIKSKTVGDGQHGT
                     ARFATKKEIEETYVEVAYEPEKWRKGENLPTAQGLVLGSIERAGKLYALVDTGDVHCLM
                     IGAAGVGKTAHFLYPNIEYACACGMSFLTTDTKGDLYRNYAGIAKKYYGYQTAVIDLRN
                     PTRSDGDNMLHLVNKYMDEYLADHNNLSAKAKAEKYAKITAKTIISSGGADSASYGQNA
                     FFYDAAEGVLTAVILLIAEFCPKEKRHIISVFKLIQDLLAPSKVKGRNQFQLLMAKLPD
                     THKAKWFAGAALNTAEQSMQSVLSTALSRLNSFLDSELEQILCFDTAIDAEMFCKQKTA
                     VFLVMPEEDNTKYFIISLILQQLYREILVVADENGGKLDNRVVFYWDEVGTIPKIESAE
                     MMLSASRSRRVGIVPMIQSFAQLNKNYGKEGAEIIIDNCQDTIFGGFAPNSESAEVLSK
                     SLGNKTVMSGSISRGKNDPSQSLQMIQRPLMTPDELKSLPKGNFIVSKTGSHPMRTKLK
                     LFLKWGIIFEEPYEIEEKSARKVAYADKQEIEEEIIRRYMCCVDEEPESTEQGTASRSG
                     GMLQSQMNETVTKVRQALRTED"
     PFAM_domain     7610..8899
                     /aSDomain="T4SS-DNA_transf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02534.16"
                     /description="Type IV secretory system Conjugative DNA
                     transfer"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2472_0136"
                     /evalue="9.50E-41"
                     /label="ctg1_2472"
                     /locus_tag="ctg1_2472"
                     /protein_end="518"
                     /protein_start="88"
                     /score="140.2"
                     /tool="antismash"
                     /translation="GKLYALVDTGDVHCLMIGAAGVGKTAHFLYPNIEYACACGMSFLT
                     TDTKGDLYRNYAGIAKKYYGYQTAVIDLRNPTRSDGDNMLHLVNKYMDEYLADHNNLSA
                     KAKAEKYAKITAKTIISSGGADSASYGQNAFFYDAAEGVLTAVILLIAEFCPKEKRHII
                     SVFKLIQDLLAPSKVKGRNQFQLLMAKLPDTHKAKWFAGAALNTAEQSMQSVLSTALSR
                     LNSFLDSELEQILCFDTAIDAEMFCKQKTAVFLVMPEEDNTKYFIISLILQQLYREILV
                     VADENGGKLDNRVVFYWDEVGTIPKIESAEMMLSASRSRRVGIVPMIQSFAQLNKNYGK
                     EGAEIIIDNCQDTIFGGFAPNSESAEVLSKSLGNKTVMSGSISRGKNDPSQSLQMIQRP
                     LMTPDELKSLPKGNFIVSKTGSHPMRTKLKL"
     CDS             9151..9405
                     /locus_tag="ctg1_2473"
                     /transl_table=11
                     /translation="LSKKEIYETELPHRAVAVYLYLKDRANKEGTCYPAIGTIARELHL
                     SVSTVKRAISDLEENGFIRKKQRWRDNGGRSSLLFEIIR"
     PFAM_domain     9178..9339
                     /aSDomain="HTH_36"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13730.8"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2473_0137"
                     /evalue="2.70E-13"
                     /label="ctg1_2473"
                     /locus_tag="ctg1_2473"
                     /protein_end="63"
                     /protein_start="9"
                     /score="49.7"
                     /tool="antismash"
                     /translation="ELPHRAVAVYLYLKDRANKEGTCYPAIGTIARELHLSVSTVKRAI
                     SDLEENGFI"
     CDS             9636..10004
                     /locus_tag="ctg1_2474"
                     /transl_table=11
                     /translation="MDKYEELIAVFSETLKQSRDYHIAYMYQVGYVSVLGLYERDSTQN
                     NSMKIDEVFHSPEEMADSLLRNWRWQWFYKNRKLLGCQDFENICNLDNKIPDLLQEEYR
                     QSIQILQNKIHIALQVEN"
     CDS             complement(10001..10570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2475"
                     /sec_met_domain="AgrB (E-value: 1.4e-38, bitscore: 129.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHLSIVLTNYIFKKGIIDKKNYEIYQYGFQCFLEVSASTICSIV
                     IALLLHMFSECLFFFLLFIPMRSFSGGLHLKTYFSCFIGSCLILTTTLLIVKYLTIPIP
                     ISFMLYVFCAIIVLIIGPVDHPNREVDSQENRIFIRRTHFTLLFSFLLAVIFAITRNTR
                     YLFLQAIVFAFICITSFIGHIAYKQS"
     PFAM_domain     complement(10037..10549)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2475_0138"
                     /evalue="1.10E-37"
                     /label="ctg1_2475"
                     /locus_tag="ctg1_2475"
                     /protein_end="178"
                     /protein_start="7"
                     /score="129.3"
                     /tool="antismash"
                     /translation="LTNYIFKKGIIDKKNYEIYQYGFQCFLEVSASTICSIVIALLLHM
                     FSECLFFFLLFIPMRSFSGGLHLKTYFSCFIGSCLILTTTLLIVKYLTIPIPISFMLYV
                     FCAIIVLIIGPVDHPNREVDSQENRIFIRRTHFTLLFSFLLAVIFAITRNTRYLFLQAI
                     VFAFICIT"
     CDS             complement(10655..11962)
                     /locus_tag="ctg1_2476"
                     /transl_table=11
                     /translation="MRGYLSVISGFLLPALQLLIIQRYITTLFGPGNRKPAGIISWFLY
                     YAFLVATGFELLFPPQFLLVWNIFMVFMISTVTRKESLKRRCISTLLICTAWMLVEVIV
                     LLVLEAIGTDESVINDAGSFASKMCMLLLSVLLGRYAKKKQYAEIPLRYFIIILLVPAS
                     SIYMMHHILHMAAFHTEYSFFSVAAGILLLLVNYVIFTVYDRMGQAAELQSRNRLYEQQ
                     LDLCSHQAEEREGYYLELRRMRHDMKNHLSGILGMVNAGQTKEASDYIQKMLDDGIGTG
                     ADEISHTGNIVVDSLVNHKYALAQKDGIQFEARVFIPSVLPFQSGHLAIIFGNLLENAL
                     EACRKLPQEQRYIMLEATYIKEMLQICIKNGSPEKLKKDSSGRYLTTKKDTGCHGIGLA
                     SVEQALADYDGELFTQHEKGEFQVSAVLYSNSIEEK"
     PFAM_domain     complement(10682..10984)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2476_0139"
                     /evalue="1.20E-21"
                     /label="ctg1_2476"
                     /locus_tag="ctg1_2476"
                     /protein_end="427"
                     /protein_start="326"
                     /score="76.6"
                     /tool="antismash"
                     /translation="HLAIIFGNLLENALEACRKLPQEQRYIMLEATYIKEMLQICIKNG
                     SPEKLKKDSSGRYLTTKKDTGCHGIGLASVEQALADYDGELFTQHEKGEFQVSAVL"
     CDS             complement(12173..12679)
                     /locus_tag="ctg1_2477"
                     /transl_table=11
                     /translation="MLKIAICDDDLGFTGSLENLVLEESQSMGVRVNTDVFSDGKTLLK
                     SIQSGERYGLIFIDIEMEQIDGISAARKIRETDHSVLFIYISGYDKYLKELFEVEPFRF
                     LSKPLDKEKFRRYFKEACHRIGETEVFYQFKFNKKIQKVPLKDIVYFESRNRVVHIFIF
                     LWKTE"
     PFAM_domain     complement(12332..12670)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2477_0140"
                     /evalue="1.60E-14"
                     /label="ctg1_2477"
                     /locus_tag="ctg1_2477"
                     /protein_end="116"
                     /protein_start="3"
                     /score="54.1"
                     /tool="antismash"
                     /translation="IAICDDDLGFTGSLENLVLEESQSMGVRVNTDVFSDGKTLLKSIQ
                     SGERYGLIFIDIEMEQIDGISAARKIRETDHSVLFIYISGYDKYLKELFEVEPFRFLSK
                     PLDKEKFRR"
     CDS             complement(12657..13058)
                     /locus_tag="ctg1_2478"
                     /transl_table=11
                     /translation="MTENRIRELRRSHNMSQEALGTIINTTQQAVSKMEKDTCAISTDL
                     LISMARYFNVTTDYILGLSDIKRDLSGQIRMNQEMDQCYDIVLRYNNLTDTNKKTLQCL
                     LKRLEQAQLEEEEADIAEEVLKNAEDSHM"
     PFAM_domain     complement(12879..13043)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2478_0141"
                     /evalue="1.50E-11"
                     /label="ctg1_2478"
                     /locus_tag="ctg1_2478"
                     /protein_end="60"
                     /protein_start="5"
                     /score="44.3"
                     /tool="antismash"
                     /translation="IRELRRSHNMSQEALGTIINTTQQAVSKMEKDTCAISTDLLISMA
                     RYFNVTTDYI"
     CDS             13514..15130
                     /locus_tag="ctg1_2479"
                     /transl_table=11
                     /translation="MEKIEKITIRLVMLLIGFSLLFPVRALAAEKDEITEKKQIIFLLD
                     ASKSMQGDGQWIEAADSACMIASALPKEYEVALLVYNTEIVYEEDFGNINQKTRHALET
                     VELQGYTTPAVALETAADMFDSAAADKRVVFISDGEISLRDQSKTETAIRQFENMVDQI
                     AEKGIKIDMFAIPNDKTENEVSYGTKVTSGEQYTVGENQTIEEITAKYLFQTLQIEKIE
                     LGEAVSGEGNMTVDLQDTYMQNAKILLVSGENIEDFHVTGQCESLNMLQGNKFAVAELE
                     NPLERQITMDYSLENRGNVHIYLIKEYFLKADMEKSYTSEEGTFTLKVNVVNHQDKPVL
                     DSETLKNSISVLIDGQESSYEVENGTALVPYQTDKTTNVNVEVTTQTSGNVIHYIETTD
                     MVELTVPVVEEEPDYTVLWIVIISLCAVALLLSVLYERKKQKKNDGEAGSIIIEPSEPP
                     VVPKYDFSGQLAVYLLKGEREDDIPPCSIKLFGKSRKSISFDWVKDRCGIDYKLSDADK
                     IRFTGGKDHTLCFKTPVMQPS"
     PFAM_domain     13631..13933
                     /aSDomain="VWA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13519.8"
                     /description="von Willebrand factor type A domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2479_0142"
                     /evalue="1.40E-09"
                     /label="ctg1_2479"
                     /locus_tag="ctg1_2479"
                     /protein_end="140"
                     /protein_start="39"
                     /score="38.6"
                     /tool="antismash"
                     /translation="IIFLLDASKSMQGDGQWIEAADSACMIASALPKEYEVALLVYNTE
                     IVYEEDFGNINQKTRHALETVELQGYTTPAVALETAADMFDSAAADKRVVFISDGE"
     CDS             15273..17453
                     /locus_tag="ctg1_2480"
                     /transl_table=11
                     /translation="VNTITQTNRTILFEEINPEKLNLLTLVGDVRGVNSVSDDKIKEIN
                     DALLVRSFDEFLEKFEPVVYSYFDANNQKVIYTLKKPENIEDELLSEIHLNRQNDYLKM
                     LMTLVEAKRAEGSINVDFKFEKLTDMISPKKVMDDIRQNRKELQYTYSEYAKLEDGDPK
                     KLDTADKLNLMFEEASVNYNNVMAMLPLAIEDIKTRLLLGDGQTKKDEAPLSLGVLSMD
                     EHGELKILEAPKENKKELMVLDDNANAGLIQAIEKDYMDLNEDGNEYVKSLVARTFCPL
                     ASTMESVVDIEKEVSNYNSYLEFYKRSKDDFIKTVKPLVEKIMGVWAFFEQYPRNCKGM
                     RPSMVISNVSNDMLAKSSNIPRLLAYLNTVNAKNDFENTIWYAIVPSVSLNSSSKLKAV
                     RQRFQGNENVEKEDVNSVESLVRILDALKDYEVQCFFSYETGDKTTFNIMATEGIEKYE
                     TKCAQLIGKPFSEYAIPCIPNFTVIPKDKSGVILDNRMYVTEQNTAALSKEKEDIMKIW
                     IDGVYIGAAYVAAGLVAAYQSPDYLKEVFKKNVDEQLPGVRFDIESGDHALQVRTTMAK
                     EITGYTNDIKSDINRKNFGFVFSSENAVLKDLNIQNIMVYKARNLLTDGKSYEPIYKTQ
                     VTTYIQRVMRLATGDFKQENIVEFFSSKPTSQRSRWMEKKDYINAIIGNGDDIRYSIDE
                     TAGYCTLDIAFNGNVKNLEIEINRVNNEDRTF"
     CDS             17488..17916
                     /locus_tag="ctg1_2481"
                     /transl_table=11
                     /translation="MGFRLAVSGGAESISLDERTIEKVSFGSDSAADSNARATDFGIAV
                     KITGKMLYKVGADGDDGTLGLAKWSQVPSEQADCYRSAKIDVVSAGQVVREYTIPNAFV
                     MEYKEHLDDETGVGTFYLHIKQKKDENDAVKIEGGYGE"
     CDS             17984..18409
                     /locus_tag="ctg1_2482"
                     /transl_table=11
                     /translation="MSFLVKVEGSESFEVAKECVRSVNVTTDIPLDSNARTKDVGATMV
                     ITGKILAALDGDITDSTRKLALWSVVSAEKADCYRKVTVEHVAGGVMERKYCFPNAFVI
                     KYSEDFDNKEGVGIFTLVLRQKKDKIASVAVEGNYSA"
     CDS             18517..18936
                     /locus_tag="ctg1_2483"
                     /transl_table=11
                     /translation="MNPYQVLGVSQTDDEDIIKKAYRKAAKECHPDTHPGDKRAEERFK
                     EIGEAYRILSDKQKRKEYDARAAQREQESATGRNSAQTGRRSAGGSIYPGDIEKEFERF
                     FSKGVQSEKKENSSQQKINPMDVTGLFERYMGFKH"
     PFAM_domain     18520..18708
                     /aSDomain="DnaJ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00226.33"
                     /description="DnaJ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2483_0143"
                     /evalue="2.30E-26"
                     /label="ctg1_2483"
                     /locus_tag="ctg1_2483"
                     /protein_end="64"
                     /protein_start="1"
                     /score="91.8"
                     /tool="antismash"
                     /translation="NPYQVLGVSQTDDEDIIKKAYRKAAKECHPDTHPGDKRAEERFKE
                     IGEAYRILSDKQKRKEYD"
     CDS             18989..19525
                     /locus_tag="ctg1_2484"
                     /transl_table=11
                     /translation="MNKKNFMDMMICSLSAAIIILCFTYMEQSRGRDTLTAVCGIVFLA
                     FLLLAVMDSLPTKRKRGANGRGIQELLLLDEEGNEISAWHIGGKTSLLIGRDEHKENVD
                     INLQNTEYGGMVDRQHAVLNYAAGQWYIEDLGSRNGVRIQDAKDGKLYQVSKEHPCRIN
                     AGDIIFIGNTRLRAK"
     PFAM_domain     19265..19501
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2484_0144"
                     /evalue="1.20E-10"
                     /label="ctg1_2484"
                     /locus_tag="ctg1_2484"
                     /protein_end="171"
                     /protein_start="92"
                     /score="41.6"
                     /tool="antismash"
                     /translation="LIGRDEHKENVDINLQNTEYGGMVDRQHAVLNYAAGQWYIEDLGS
                     RNGVRIQDAKDGKLYQVSKEHPCRINAGDIIFIG"
     CDS             19539..20045
                     /locus_tag="ctg1_2485"
                     /transl_table=11
                     /translation="MSGNLIRCQNGHLFSSRRYGTVCPYCNIETATKEKKSVEKSQEEI
                     EDILFLEEEHPVCGWIVCVKGPRRGKDYRVMDGKNFVGRADDMDIQILGDNKIARRNHA
                     VIVFDAKKRENMILPGDSNGLVYLNGEAVYLPQPLSAYDVIEMGESTFLFVPFCGEHYM
                     WEDDK"
     PFAM_domain     19782..19982
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2485_0145"
                     /evalue="2.80E-06"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="148"
                     /protein_start="81"
                     /score="27.7"
                     /tool="antismash"
                     /translation="VGRADDMDIQILGDNKIARRNHAVIVFDAKKRENMILPGDSNGLV
                     YLNGEAVYLPQPLSAYDVIEMG"
ORIGIN
        1 aaccgcagga atggtgatga catcatctgc ggtccatttt ttatctgtgg ggatagcccg
       61 gacggtgatt tcatttccct gacggagcag cagatcgaga aatataccag acgatttgga
      121 gagattgagc agtttacagg gcaggaaccg gaactggagc cacatatgac catcctcgct
      181 ttttaagaaa gtgacaggac aatggaaagg aaacggcaca gacaccgccg tgtgagcctg
      241 cgtgtggcaa cgtgtgccgt tattctgcaa aactggataa agtgaccgat taagctatat
      301 tctgccctgt atgagccgat ttggagaaaa taacagaaaa cccggagtgc ggaggcatcc
      361 aagactccga aaatggggat gaaacggggc tgtaaaacag ggtcgaaaat agtgcaggtt
      421 aaaggggtta tgccgctttg gggcggccta acccgtgaaa cacccaccgg cagagccgtt
      481 gggggatttg tggtatggca taactttttt gaagatttgg aagaagttat gctaattttt
      541 attattttca agaattgaaa ggcattgaag gaacttaaat ttatgccttc cgcaaaaatg
      601 cttgcaggca gaagaaaaaa ggaaaggaat tgagtagtcc cgtggggtaa ggtgcgcacc
      661 actaccggta tgggactatg aaagttttgg aattatttgc aggaacacgg agtatcggga
      721 aagcctttga gagtagaggg catgaagtat tcagtgtgga gtggtccaag gactttgaga
      781 acattgattt gtatgaggac attaataagg taaccgcaga ggatatcata agactttttg
      841 gaaagccgga tgttatctgg gcaagtccgg actgctccac attcagtatt gctgcaatca
      901 gtcatcacag aagaaaaaat ccggataccg gaagtctgga gccggtcagt acctatgcaa
      961 aattttgtga tatggtggac cagcatgtgc tgaaactcat tgaagagtta cagccaaggt
     1021 attattttat tgaaaatccc agaggcggta tgcggaagat ggaatggatg aaaggtctgt
     1081 caagatacac cgtgacatat tgtcagtatg gtgacaatcg gatgaaaccg actgacatct
     1141 ggacgaatca ccctgatcca aaatttttgc cgatgtgtca taatggagat tcgtgtcatg
     1201 tggcagctcc aaggggaagc aagactggga cgcagggatt aaaaggtgcc agagaaagaa
     1261 gtgtgatacc gcagaagttg tgtgaacaca ttgtagatat ctgcgaagag taatttatga
     1321 aggaggatga gagtggcaag cgaaggaaaa gtaaggagag gattttatat tgaggaagac
     1381 ttgctggagc aggtggatgg attgttggag caggcagatg tgaaatcaag aaatgaattt
     1441 ttgaatcagg cattaaaatt ttatatcggc tatctgacat cagagaaaat cgaaaactat
     1501 atgctttcca ctatctcatc agtgatgcat tccacagtga aggatagcga gaaccgaatg
     1561 gctcgtgcga tgtataagct ggcagtggaa acatcaaagc tgtcccatgt gattgcatat
     1621 agtcatggag tggatgaaga ggccctaagg aaactacagg caaagtgtgc agaggaagtg
     1681 aaacgtatta atggaacagt tagttttgag agtgcctacg aatatcaaaa agggtagtca
     1741 tggagcttag tggtgtgata ttattgtgaa tatagcatat tttgattttc atgttggagt
     1801 ttgatggata gtaaaataag atttaactga tttaggtatg attgacatag ggagaaaaat
     1861 aatatgagta atgtacgttg ggaatctcca tttccgtatt cattagcatt taatttgttt
     1921 aagcaacatt ttgaggaaat aaatcgttca tattgggctt ttgttccagc agcaaatacc
     1981 atcaaatcat ttgcaaagaa gagtttgctt gatgataatg ctgacccgaa aaagtttttt
     2041 ttgattccag atgaagagga tcgtaggatg gctcctacat atggcgagtg gaaaactgat
     2101 ttttcggaat atgtaaatta ctcaaggttg aatattatta tgcttttaag ttcatgtttt
     2161 gaaacatatt taaggacggt ggtttctctt tcttttgagt caaaaccagg agtgattatt
     2221 aattgccaag atgctgttga cggcgcagca ctgctaaaaa gagatattat gtatggtaac
     2281 atgaatgata aatcgtatcg ttttggtgaa gtgattgagg aagtgtgtcg cggggaatgg
     2341 gcaaaccgtt tttgtgcatt tcaaaaatat tttggcaagt taccacctca attattagat
     2401 ttatctaagg atttagatga acttagagtt actaggaata atttaggaca ttattttgga
     2461 agaagaaagg atgtatatag tgctccaatc gatttcgagc cgatagaaac tacaagaata
     2521 tcacatgaac ggattttaaa atatttcaaa ttgatttact cggctgcaaa aatgatagat
     2581 ggctatttac acaaaaacat cattggctcc tatgatatta taaaaaaata tttcttttca
     2641 ctgtcaaatg gtgagatatt aactgaccct tataatccag atgcgtatca attacgaaaa
     2701 ctattgggta gacatgatct tacaagggtt ggtaagaaat actatgatga gttagtaaca
     2761 tattgcgaga caaattatgt tgagagtgaa acagattgta tatttacaag gaaaagatgc
     2821 gttaaagaga ttaatagaag gttaaaagaa tcaggcacta agttacttta taatggacag
     2881 gtagttccgt ttgatccgtt gtcgtttaaa cttcttttaa taaaagataa tctttatgac
     2941 aaagacaatt attctgaaag aaaaataggc aacaatcgtc aagtgcaata tttacattca
     3001 ttggctttaa ttgattatgt tacaaaaaaa ctagaatcca attctaattc tattatggaa
     3061 aaattgaagg aagaaaagta ataatgccaa aattaatttt acgttgcaac tatctcaaga
     3121 atgcccctcc ttcacatctt gccaattaca tgaattatat cagcacccgt gaaggtgtgg
     3181 agaagataga caatacttgc ggtttgcttc cggctacggt caagcaaaag gaactgatag
     3241 cagatatttt gtcaaagata gaagatgcag accgcatgca tgagtattat gattatctcc
     3301 agaggccgac aagggagaat gcgacagagt ttatcacgca ggcattggaa aataatctgg
     3361 atatcatagc caagaagaaa aattacatag attaccttgc aaacagacca agagtagaaa
     3421 aaataggtac tcatggtctg ttttctaatg agggggagtc tattgtgctg tcccgtgtgg
     3481 cagaggaggt ggcaaatcat ccgggagtga tatggaccaa tgtcattagc ctgcggagag
     3541 aggatgccga aaggtttgga tatgacagtg ctgcacagtg gcaggcactg ctacggagca
     3601 gggtggaact tctgtgtgaa aactataaga tagacagcag aaacctcaaa tggtatgcag
     3661 cattccataa cgagtcccat catcctcatg tacatctggt ggtatactcc acaaatccat
     3721 cggaaggtta tctatcgcca aaaggtatcg acaccatgag gtctacctat gcccatgaca
     3781 ttttccgtca ggagtttatg agtatttatg aaaagagaac acagcaaagg gaacagttga
     3841 aagagcaggc aaataaaagt ctgctttttt tagtgcagca aatgcaaagt ggtatctgtc
     3901 accatgaaaa aattgcagaa cagatgaaag tgttatccaa acgattgatg aataccagtg
     3961 gcaaaaaggt atacggatat ctgaaagcag atgtaaaggc aatcgtcaat ggtattgtgg
     4021 atgaactggc aaaggaagag aaagtggcag agtgctacaa acaatggcta gagagcaaaa
     4081 gtgagatact gcattattac aaggatgcag atgcagagca gcttccgttg tcagagcaga
     4141 aggaattaaa aagcatcaaa aacatggtca tcagggaagc agtccgatac ggagaagggt
     4201 atctttatac agaggacgag ggactggaag atttggaaac cgaaagggaa gaaatggatg
     4261 cagatgattc tgaagtgtca gaagatatgg cggaagttct agcagattat tctgatgcgg
     4321 agccggaaac ggaagaaccg gacagtcagg agttttatgc caagtggacg gatgcttata
     4381 aagaagcgag ggaatatctg tatggcacat cggagatgga gccggatgag gaggctgcct
     4441 atgaaatcat gaaagaggag gcagagcagg gaaatgccta tgcaatggca gacatgggta
     4501 agatgtatgc acagggcatt tttgtggaag cagacaaggc gaaagcacag gagtggtatg
     4561 aaaagtccct aaaggcaatg cttatcgtgg aaggcagaaa agaaaacact tatctggaat
     4621 accgtatcgg aaaaatgtat cagtatggct tgggaactga ggagaatctg ccggaggcag
     4681 ccaagtggtt tgggatggca tcaagtaaag agcataagta cgccttatat tcccttggca
     4741 tgttgtatct gcatggcaaa ggtgtggagc aggacgaaga gaaagcctgt cagttgtttc
     4801 agcgttccca taaaaagggc aatccttacg catcctttga attgggaaaa ctgtatgaag
     4861 ctggaagagg aagcgagagg aatacggatc tggcggggaa gtgctaccgg gtagcgtttc
     4921 ttggtttctt aaatctggaa aagaagtcca gggatgatac cttatggtac cgaattggaa
     4981 ccatgtattt gcaaggagtt ggtactgaag cagatgaaaa ggaagccgaa aagtatctcc
     5041 gtaagtctgc ggattatgga aatacccatg cagcctatca attggcaaag ctgtacatcc
     5101 gtcaggaaac ggagaaacga aaaacgaacc cggaagaaat accggactat gaaaaaatta
     5161 gacaggcatt taaatggctg acagcagctt ccgagcaggg caattctttt gctgattatg
     5221 cccttggaaa actgtatgcg gatggggaac tgacagcaaa ggatatggaa aaggcattct
     5281 atcatttaca cagagcagca gatgcagata atgtctatgc gtggtacaag ttgggcagat
     5341 tgtatctgtc ggatgagtat aagaacatcg gcagggcagt ccattatcta aaactggcag
     5401 caaatcagaa aaatgaattt gcattatacc ggcttgggaa gttatatctt gcaggggagg
     5461 aggtggcaaa aaatgtagaa cttgccatac ggtatctgga agagtcagcc ggcgtgggaa
     5521 atcagtatgc acagtatgtc cttggcaagg tgtatatgat ggaaaaagag gtagagcagg
     5581 ataaggaaaa agcatacgaa tatttcagat tggcagcgga gcagggaaat gtgtacgctg
     5641 tttatttttt ggaacactgg aatgatatgc cccatccgga tttactacta atggcaacca
     5701 gactcatgca tcatctggaa aatatactaa aggacgatgt ttccggaaag aaaggagaca
     5761 gacgaactgg aatggatcgt aagctggcta gaaagataag acaaaagaaa atcgcacaag
     5821 gtcatgcaag agatgacagg gaagaaatgg tacagacaca gtaaaggagg agcagattgg
     5881 gagatttcat ttattttaca gaggagcaga aggaaagagc caatgcagta cccatcatgg
     5941 atattttgaa acgggagcat gaagaagtgg aacgctccgg aaatgaatgg agatggaagc
     6001 ggcatggtag tgtgacgttc cgtggaaacc gctggtacag acacagccaa cagatgggaa
     6061 gccatgctat tgatttcatg caggagttct ttgggatgtc ttatccggag gcagttacct
     6121 atttgttaga tggggaaacc ggacaggtca ttcatggagg aagtccgccg agggaaacaa
     6181 caggcaagaa atcagtacgt cccaaggaag agaaaaccac agaagaaaaa gaaccgaaag
     6241 tattaatacc gccggaaaag aacgatacca tgaaaagagt atatgcctat ctgatgcaga
     6301 aaaggcatat cagtagggag gtgctgtcct tttttgccag acagggaaca ctgtatgaat
     6361 cggccgggca tcacaacgct gtatttgtcg gagtggataa ggaagggaat gcacgccaca
     6421 tacataaaaa gggtacttgt tcggatggca ggagcttccg catgaacgag gatggttcgg
     6481 actcttccta tgggttcggt tatgtcggag caggaaataa gctgtatgtg tttgaggcac
     6541 ccattgactt tctatcattt ctgacgttgt accctgtaaa ctggcaggag aacagttata
     6601 ttgtcttaaa cggagtttca gaacatgcca tgctgcagat gttaaaggat tatgcgaatc
     6661 tggatacggt tgtgttgtgc ctggaccatg atccggcagg catagaagcc tgtggaagac
     6721 tggcagagat tttggtgcag aatggataca ggcagattaa gaatttaaaa tccacctgca
     6781 aggactggaa tgaagattta aaacttctgc atggggaaga ggtaatccca gcacaggagc
     6841 atccaaagat tttggaatgc gatgcatgga tggaaatact aaagcaggtc acagacagtg
     6901 tggatatcaa atatgccacc aaggaaaatg tgtgccggta ttatcaggac atttataatg
     6961 cactgaagaa aggaaacgga aaagaacatc tggaagatgc tttcgatggc gggggaatgc
     7021 ttttaaccgg ggtgctggtt cgatgcatgg agaaaacagg cagggaactt ggcagggaaa
     7081 caagtgcaga tgaaatactg gataacctgc ataagcgata ccgaccacat agggataagg
     7141 ggaactacaa tacaaggctt cggaacatgc agaaagcctt tgaggaactg atggaggtat
     7201 ttgacaaaga ggatttgtcc ttaaaagaga ataaagaaga atttgtgaag aagtctatga
     7261 gcctgacgat ggaatgcatc aaggctcata ttttttttgc aacagaatat gaagaaccca
     7321 tacaaaggaa ggagatgagg atggaatgca gccagccgtg atgttattgg tgtcaggggt
     7381 aattatgttt tccgtgattg aaggactttc cctgctggca cattattata cgctcaatgg
     7441 aatcaagagt aagaccgtag gagatggcca gcacggtacc gcccggtttg ctaccaagaa
     7501 ggaaattgaa gaaacctatg tggaagtagc ctatgagccg gagaagtgga ggaaaggaga
     7561 aaacctgccg acagcacagg gacttgtgct tgggagcatt gaaagggcag gaaagttata
     7621 tgcccttgtg gataccgggg atgtgcattg tctgatgatt ggagcagcag gtgtgggtaa
     7681 gacagcacat tttctctatc ccaacatcga atatgcctgt gcctgcggaa tgagttttct
     7741 gactacggat accaagggtg acctttatag aaactatgca ggaattgcca agaaatatta
     7801 tggataccag acagcagtga ttgacttaag aaaccctacc agaagtgatg gcgataatat
     7861 gctccacttg gtaaacaagt acatggatga gtatctggct gaccataata acttaagtgc
     7921 caaggcaaaa gcagaaaaat atgcaaagat tactgccaag accatcatat cctccggggg
     7981 agccgacagt gccagctacg gacaaaacgc attcttttat gatgccgcag aaggtgtact
     8041 gaccgcagtt attttgttaa tagcagaatt ttgtcccaag gagaaacgac acatcatcag
     8101 tgtgtttaaa ctgattcagg atttactggc gccatccaag gtaaaaggaa gaaatcagtt
     8161 tcagttactg atggccaaac ttccggatac ccataaggcg aaatggtttg ccggggcagc
     8221 tttgaatacc gcagagcagt ccatgcagtc tgttctttcc acagcactct ccagactaaa
     8281 ctctttcctc gattctgaac tggagcagat actgtgcttt gataccgcta ttgatgctga
     8341 aatgttttgt aagcagaaga cagcggtatt tttagtgatg ccggaagaag acaacaccaa
     8401 gtattttatt atctctctga ttttgcagca actctatagg gaaatccttg tggtggcaga
     8461 tgagaatgga gggaagttag acaaccgtgt ggttttctat tgggatgagg tcggaaccat
     8521 accaaagatt gagagtgcgg agatgatgct ctctgcatcc cgttccagaa gggtaggtat
     8581 cgtacccatg atacagtcct ttgcacagct taataagaac tacggaaaag aaggggcaga
     8641 gattatcatc gataactgcc aggataccat cttcggtgga tttgcaccaa actcggaatc
     8701 cgcagaggta ctgtccaaga gccttggaaa caagacggtc atgtccggct ccatcagcag
     8761 gggaaagaat gatccgagtc agtccctcca gatgatacaa agaccattaa tgacacctga
     8821 tgaattaaag tccctgccaa aaggaaactt tatcgtgtcc aagacaggca gccatcccat
     8881 gaggaccaag ctgaaactgt tcctaaagtg ggggattatc ttcgaggaac catacgagat
     8941 tgaggaaaag tcagcaagaa aggtagccta tgcagacaag caggagattg aagaagagat
     9001 tatccgcaga tatatgtgtt gtgtggatga ggagccggaa agtacggaac agggcactgc
     9061 gtccagaagc ggtggtatgc tgcagtctca gatgaatgaa acggtgacaa aggtaagaca
     9121 ggctcttaga acagaggatt aggtgattag ttgagcaaaa aagaaatata tgaaacagaa
     9181 ctgccccata gggctgtggc ggtatatttg tacttaaagg atcgtgcgaa taaggaaggc
     9241 acctgctacc cggcaatcgg taccattgca agggaactgc atctgtctgt cagcaccgtg
     9301 aaacgtgcca tcagcgatct ggaggagaac ggatttatac gcaagaaaca gcgctggcgt
     9361 gataatggtg gaagaagtag tctgctgttt gaaatcataa ggtaagcaca aaggggatac
     9421 tgcgctggtc aggtggacta tggtatggtt caccatggcc tgtgcaggga acttttcaat
     9481 ttaaggatta agacagagaa aatggaattt ggtattattt gatgtagtaa tagttaataa
     9541 aagaaataag tgttatgata agttttaata tgagaagtaa ataataacca ttataacctt
     9601 tatgcaatgg tgtgatattg aggagagatt attagatgga caaatacgag gagttgatag
     9661 ctgttttttc agagacactt aagcaatcaa gggattatca tattgcctat atgtaccaag
     9721 tgggctatgt atctgtactc ggattgtatg aaagagatag tacacagaac aactcaatga
     9781 aaattgatga ggtttttcat tctccggaag aaatggcgga cagtttgctg cgtaattggc
     9841 gctggcaatg gttttataag aatagaaagc tgttaggctg tcaagatttc gaaaatattt
     9901 gtaatcttga caataaaatc ccagacttgc ttcaggaaga atacagacaa agtatacaaa
     9961 tccttcagaa taaaatccat attgctttac aggtggaaaa ttaagactgt ttataagcaa
    10021 tgtgtccgat aaaagaggtt atacatataa aagcaaatac aattgcctga agaaacaaat
    10081 atcttgtatt tctggttatg gcgaaaataa ctgcaagcag aaaactgaat aataaggtga
    10141 aatgtgttct tcggataaaa atacggtttt cctgtgagtc aacttccctg tttggatgat
    10201 ctacaggtcc tatgattaaa actataatgg cacaaaacac gtacagcata aaggaaatag
    10261 gaatcgggat agtaaggtat ttcacaataa gcagggtagt agttagtatc aagcaggagc
    10321 cgataaaaca ggaaaaatag gtttttaaat gcaagccgcc gctgaatgaa cgcattggaa
    10381 taaacaatag gaagaaaaac aggcattcgg aaaacatatg cagcaacaag gcaatcacaa
    10441 tactgcaaat tgtgctggca gaaacttcta aaaagcattg aaagccatat tggtatattt
    10501 cgtaattttt tttatcaata attccctttt taaagatata gttcgttaat acaatagata
    10561 aatgttccat aacagaggtc tcctttaata atcttatagt ataaaacaaa gaaagaggaa
    10621 aaacgggtag ttgtagaaaa taggaaaatg caggtcattt ttcctctatg gaattactat
    10681 acaacaccgc agaaacctga aattctcctt tttcatgctg ggtaaacagt tccccatcat
    10741 aatcagccag tgcctgttct accgaggcaa gaccaattcc gtgacagccg gtatccttct
    10801 ttgtggtaag gtatcgtccg ctgctgtctt tttttaattt ctctggacta ccatttttta
    10861 tacaaatctg gagcatttct tttatataag tagcttccag catgatatat ctctgttcct
    10921 gcggcagctt cctacaggcc tccagtgcat tttccagcag atttccgaag ataatggcaa
    10981 ggtgtccgct ctggaacggc agtacggacg gaataaatac ccttgcctca aactggatgc
    11041 cgtccttctg ggcaagggca tacttatggt tcacaaggga atccaccacg atgtttccgg
    11101 tgtgggagat ttcgtctgcg ccggttccga taccatcatc cagcatcttc tgtatgtaat
    11161 cactggcttc ttttgtctgt ccggcattta ccatgccaag aatccccgat aagtggttct
    11221 tcatatcatg ccgcatccgc cgcagttcca gataataacc ctcccgttcc tctgcctgat
    11281 ggctgcataa atctaactgc tgttcataca gccggttccg ggactgaagc tccgctgcct
    11341 gtcccatccg gtcatacacc gtaaaaatca cgtaattgac aagcaggaga agtatgcccg
    11401 cagccaccga gaaaaaagaa tattccgtat gaaatgctgc catgtgaagg atatggtgca
    11461 tcatataaat gctgctcgcc ggtaccaaaa gaattatgat gaaataacgc agcgggattt
    11521 ccgcatactg ttttttcttt gcgtaacggc caagcagtac tgaaagcaga agcatacaca
    11581 tcttggatgc gaagcttccg gcatcattaa tgacgctttc atctgttcca attgcctcta
    11641 agaccagcag cacaatgacc tctaccagca tccatgccgt acagataaga agggtgctga
    11701 tacagcgtct tttcaggctc tcttttctgg taacggtact gatcataaat accataaaga
    11761 tattccagac cagaagaaac tgcggaggga acaggagttc aaaccctgtt gccacaagga
    11821 aagcatagta taaaaaccag ctgattatgc ctgcaggctt tctgtttcct ggaccgaaaa
    11881 gggtcgttat gtatctctgt ataatcagaa gctgcagtgc cggaagcaga aagcccgata
    11941 taacggaaag atatcccctc attcaataac cgcctttccc gctgccattg tgcagagctg
    12001 tcggcgcact tccttctgtc ggtcctcact gattttcagt tccatctctt tcccattcat
    12061 actgattgtt atgttaaaaa aattcatttt tgttatataa tcgtaattca caaggaagga
    12121 ctggtggata cggaggaaat atttccgact atttgcgagt tccttctcta cgttattcag
    12181 ttttccataa aaatatgaaa atatgcacta ctcggttgcg gctttcaaag tacacaatat
    12241 cttttaaagg tactttctga attttcttat tgaacttaaa ctggtaaaag acctccgttt
    12301 cacctatccg gtgacaggct tctttaaaat accggcgaaa tttctcttta tccagcggtt
    12361 tagagagaaa acggaaaggc tctacctcaa acagttcctt taaatattta tcatatcctg
    12421 aaatatatat gaacaacaca gaatggtctg tttcccggat ttttcgagca gcggagatgc
    12481 cgtcaatctg ttccatttca atatctataa aaataagtcc gtatcgttcc ccggactgta
    12541 tgctcttcaa aagtgtcttt ccatcagaaa atacatccgt attaacccgg actcccatac
    12601 tctggctttc ttctaacacc aagttctcaa gacttcccgt aaagccaagg tcatcatcac
    12661 atatggctat cttcagcatt tttaagtacc tcttctgcta tatctgcttc ctcttcttcc
    12721 aactgtgcct gttccaaacg tttgagaaga cactggagtg tctttttgtt cgtgtccgtc
    12781 aggttgttgt agcggagtac aatgtcatag cactgatcca tctcctgatt catgcggatt
    12841 tgcccgctca gatcccgttt tatatcggac agcccgagga tatagtcagt ggtaacatta
    12901 aaataccttg ccatgctgat aagcaggtct gtggagatgg cacatgtgtc tttttccatc
    12961 ttgcttaccg cctgctgggt ggtgttgatt atagtcccaa gggcttcctg tgacatgttg
    13021 tggctcctgc ggagctcacg gatacggttc tcagtcataa ttgtgacatc ctttctaata
    13081 actattttac ataattatta gaagtttact cacaactgta taatgtaaat caaatacagg
    13141 acggcgttaa tagaaacata atgtgcttat atatctaatc aagatgagaa tgaaagtaaa
    13201 agagttttgt gctatagaga tgacaagtta taccaatttt aaaggtacat actatagtgc
    13261 gtttccggaa aaagtgacaa attatgtcga aaattcaacg tataagagat ttcagaatta
    13321 ctcaggtata aactatatgc gtaatgaaaa gaaagtcatt ggaaaaaagc gcaaatcata
    13381 gttgtgaccg aactggtcgt gggaatggta tttctgatgg tgaataagaa agctgcctat
    13441 gcggtttggg gcgcagtaat ctggtgcgga gtaagttatc tggcatggcc agtaaagaga
    13501 tatatggaga aaaatggaga aaatagagaa gataacaatt agattagtaa tgctgctgat
    13561 agggttttct ttgctgtttc cagtaagggc tcttgcagca gaaaaggatg aaattactga
    13621 aaagaaacag attatatttt tgctggatgc aagcaaatca atgcagggag acggacagtg
    13681 gattgaggca gcggacagcg catgcatgat agcgtcggcg ttgccgaaag aatacgaagt
    13741 ggcattgctg gtatataaca cggaaattgt ttatgaggaa gatttcggaa acattaatca
    13801 gaaaaccagg catgcacttg agacggtaga gctgcagggc tacaccaccc cagcggtggc
    13861 gttggaaacg gcggctgata tgtttgacag tgcggcggca gataaaagag tggtatttat
    13921 ttccgacggg gaaatttctc tgcgggatca aagcaaaaca gaaactgcaa tcaggcagtt
    13981 tgaaaatatg gtggatcaga ttgcagaaaa gggaataaaa attgacatgt ttgcaatccc
    14041 caatgataag acggagaatg aggtttcgta tggaacgaaa gtgacgtcag gagagcagta
    14101 tacagtaggc gaaaaccaga cgattgaaga aatcactgca aaatatctgt tccagacgtt
    14161 acagatagaa aaaatagaac ttggcgaggc ggtttccgga gaaggaaata tgacagtgga
    14221 tctgcaggat acttatatgc agaatgcaaa gatacttctc gtgtcagggg aaaacatcga
    14281 ggattttcat gttacaggac agtgtgagag cctgaatatg cttcagggaa acaagtttgc
    14341 ggttgctgaa ttggaaaatc cattggaacg gcagattaca atggactatt ctctggaaaa
    14401 cagaggaaat gtccatattt atctgataaa agaatatttt ttaaaagctg atatggagaa
    14461 atcctataca tcagaggaag ggacatttac cctgaaggta aatgttgtaa accatcagga
    14521 taaaccggtt ttggattcag aaaccttgaa aaatagcatt tctgtgttga tagacggtca
    14581 ggagagttct tacgaagtgg aaaatggtac agcgttggtt ccgtatcaga cagacaagac
    14641 aacaaatgta aatgtagagg ttaccactca gacatcagga aatgtgatcc attacataga
    14701 gacaacagat atggtggaat tgacagttcc ggttgtagag gaagaacctg attatacagt
    14761 cctttggatt gtgattatat cgctatgtgc agtggcactt ttactttctg ttttatatga
    14821 aaggaaaaag caaaaaaaaa acgatggtga ggcgggttcc attatcatag aaccgtcaga
    14881 acctcctgtg gtgccaaagt atgatttttc aggacaactg gcagtgtatc tgttaaaggg
    14941 agagcgggaa gacgatattc cgccttgtag tattaaatta tttggaaaat cacgaaaaag
    15001 tatatccttt gactgggtga aagaccgctg cgggattgat tataaattat cggatgcaga
    15061 caaaatccgg tttaccggag ggaaagacca caccttatgt ttcaaaacac cggttatgca
    15121 accatcgtaa aaggaaacca gattttgaaa cgggagagaa aatattcctt atgttatgga
    15181 gaaaaaatac tgttgatttt taataatggg ggaacagaaa tcgaacttca ttataaaaat
    15241 atgaaaccaa gcgaaaggta aggaggaaca aagtgaatac aataacacag acaaacagga
    15301 cgattctctt tgaggaaatc aatccggaaa agctgaatct tctaacactt gtgggagacg
    15361 tcagaggggt aaacagcgta agtgatgata aaatcaagga aataaacgat gccttgctgg
    15421 tgagaagttt cgatgagttt ttagaaaaat ttgagccggt agtatattct tattttgacg
    15481 caaacaacca gaaagtaatc tataccctca aaaaaccgga aaacattgag gatgagttat
    15541 taagcgaaat ccatctgaac cgccagaatg attatctgaa aatgttgatg actcttgttg
    15601 aggcaaagcg ggcagaggga agtattaatg tagattttaa atttgagaaa ctgacggata
    15661 tgatttcccc caaaaaggtc atggatgata tccggcagaa tcggaaggag ctccagtata
    15721 catacagtga gtatgcgaaa cttgaggacg gcgatccaaa aaagttagat acggcggata
    15781 agctgaatct gatgtttgaa gaagcaagcg taaactacaa taatgtgatg gcgatgttgc
    15841 cgcttgcgat agaggatatc aaaacaaggc tgctgttggg agacgggcag acgaagaaag
    15901 acgaagcccc attaagtctt ggcgttctca gcatggacga gcacggggaa cttaagattt
    15961 tagaggcacc aaaggaaaac aaaaaagaac tgatggtatt ggacgacaat gctaatgcag
    16021 gattgattca ggcaatcgaa aaagattata tggatctgaa tgaggacgga aatgagtatg
    16081 tgaagtccct ggttgcgaga acattctgcc ctctggcttc taccatggag agcgtcgtag
    16141 atattgagaa agaagtatcg aactacaact cttaccttga gttttacaag cggagcaagg
    16201 acgattttat caagacggta aaaccactgg tggagaaaat tatgggagta tgggctttct
    16261 ttgagcagta tccgagaaac tgcaagggca tgagaccttc catggtgatt tccaatgtaa
    16321 gcaacgatat gttggcaaag agcagcaaca ttccgagact tttagcatac ctcaatacag
    16381 taaatgcaaa aaatgatttt gagaatacca tctggtatgc gattgttccg tcggtttctt
    16441 taaacagcag ttctaagctt aaggcggtaa gacagcgttt tcagggaaat gagaacgtag
    16501 agaaagagga tgtgaacagc gtggagtcgc tggttcgaat actggatgcg ctgaaagatt
    16561 acgaagtgca gtgtttcttc agctatgaga cgggggataa gaccaccttt aatattatgg
    16621 cgacagaggg aattgaaaag tatgaaacaa agtgcgcaca gctaatcggc aagccattca
    16681 gcgagtatgc aattccctgc attccgaatt ttacagtgat ccctaaagat aaatccggag
    16741 tgattctgga taacaggatg tatgtcacgg aacagaatac ggcagcactt tccaaagaaa
    16801 aagaagatat tatgaaaatc tggattgacg gcgtttatat aggagccgca tatgtggcag
    16861 ccggactggt ggcagcttac cagagtccgg actacttaaa agaagttttt aagaaaaatg
    16921 tagacgagca gcttccaggt gttcggtttg atattgagtc aggagatcat gcgctacagg
    16981 ttcggacaac catggcaaaa gagattacag gatatacgaa tgatattaag agtgatatca
    17041 accggaagaa tttcggattt gtattttctt cggaaaacgc agtgcttaag gatctgaata
    17101 ttcagaacat catggtttat aaggcgcgta acctgctgac agacggaaag agctatgagc
    17161 caatctacaa gacacaggtg actacttata ttcagagggt gatgcgcctg gcgacaggtg
    17221 actttaagca ggaaaatatt gtagagtttt tctccagcaa gcctaccagc cagagaagta
    17281 ggtggatgga gaaaaaagat tacattaatg cgattatcgg aaacggagat gatatccggt
    17341 attccatcga cgaaacggca ggctactgta cgcttgatat cgcattcaac ggcaatgtga
    17401 agaacctcga aatcgagatt aaccgggtca acaatgagga cagaacattt taaataaagt
    17461 ccgaaagaaa agaaggagga aatgaacatg ggttttagat tagcagtgag tggaggcgca
    17521 gagagcatca gtctggatga gagaaccatc gagaaagtta gtttcggttc tgattctgca
    17581 gcagattcca acgcaagggc aacagatttc ggtatcgcag taaagattac tggaaaaatg
    17641 ctctataaag tgggagcaga cggagatgac ggaacactcg gattagccaa atggtctcag
    17701 gttccgtccg agcaggcaga ctgctacaga agtgcaaaga ttgacgttgt atcagcaggg
    17761 caggtggtaa gagaatatac aatccccaat gcgtttgtca tggaatataa agagcatttg
    17821 gacgatgaaa ccggcgtggg tactttctac ctgcatatca agcagaagaa ggacgaaaat
    17881 gatgcggtga agattgaagg cggttacggc gaatagcatg agaagaatgc aggttcagta
    17941 ttcttcttgc ggattttaaa tattttaaaa aggagatgga attatgtcat ttttagtaaa
    18001 agttgaagga agcgagagct ttgaagtggc taaggagtgt gtcagaagcg taaatgttac
    18061 cactgatatt ccgttggatt cgaatgcaag aaccaaggac gtcggcgcaa ctatggtgat
    18121 tacaggaaag attttagcgg ctttggacgg ggatatcact gacagtacaa gaaagctggc
    18181 gttatggtcg gttgtttcgg cagagaaagc agattgttat cgcaaggtga cggtagagca
    18241 tgtggcaggc ggcgtgatgg aaagaaaata ttgttttccc aatgcatttg tcattaaata
    18301 cagcgaagat tttgacaaca aggaaggcgt cggaatcttt acgttagtgc tcagacagaa
    18361 gaaagacaaa atcgcttctg tagcggtaga aggaaattat tcagcataac ggcagggcgc
    18421 agattgtcag taaatgtgac agcctgcgcc ttaaatcagt aatcagaagt gtgcgttatc
    18481 agatttgtat tgttatgaaa aaaggttggg ataaacatga atccatatca ggtattaggc
    18541 gtttcgcaga cggacgatga ggatatcata aaaaaggcat acagaaaagc ggcaaaagaa
    18601 tgccaccccg atactcatcc gggagataaa agagcagagg aacggtttaa ggaaatcgga
    18661 gaggcatacc ggattctcag tgataaacaa aaaagaaaag agtatgatgc cagagcagca
    18721 cagagagaac aggaaagtgc gacaggcaga aacagtgccc aaacaggcag aaggagcgcc
    18781 ggaggatcga tttatccggg agatatagaa aaggaatttg aacgattttt ttccaaagga
    18841 gtgcagagcg agaagaagga aaacagttca cagcaaaaaa taaatcccat ggatgtgaca
    18901 ggcttatttg agcgttatat gggatttaaa cactgagaaa gacggtttga ctttatgaat
    18961 gcaaatttgt gggcatattg aggtgaaaat gaataagaaa aatttcatgg atatgatgat
    19021 atgcagcctt tccgctgcaa ttataattct atgttttaca tatatggagc agagcagagg
    19081 acgggataca ctcacagctg tctgcgggat tgtatttctg gcatttctgc tgctggcggt
    19141 gatggattct ctgccgacta agcgaaaaag aggcgcaaac ggacggggaa tacaggaact
    19201 tctgctgtta gatgaagagg gaaacgaaat ttctgcctgg catattggcg gaaagacctc
    19261 gcttttgatc ggacgggacg agcacaagga aaatgtggac attaaccttc aaaatacaga
    19321 gtatggcgga atggtagacc gtcagcacgc cgtgttgaat tatgcggcgg gacagtggta
    19381 tatcgaggat ttaggaagca gaaacggtgt aagaattcag gacgcaaagg atgggaaact
    19441 gtatcaggtt tcaaaggaac atccatgccg gattaatgca ggcgacatta tttttatcgg
    19501 gaacacaaga ttaagggcaa aataaggaga gacaaaacat gagtggaaat ttaattcgct
    19561 gtcaaaatgg acatcttttt tcaagcagaa ggtacggaac agtatgcccg tactgcaata
    19621 ttgagacagc aaccaaagaa aaaaagtcag tggagaaatc tcaggaagag attgaggata
    19681 ttctctttct ggaggaggag catccggtct gcggctggat tgtatgtgta aaaggcccga
    19741 gaagaggcaa ggattaccgg gtaatggacg ggaaaaattt tgtgggacgg gcagacgaca
    19801 tggatatcca gattttgggg gacaacaaaa tcgcacggag aaaccatgcg gtgattgtat
    19861 tcgacgcaaa gaaacgggag aatatgattt tgccggggga cagtaatggt ctggtctatc
    19921 tgaacggcga agcggtttat ctgccgcagc cattgagcgc atatgacgtg atagagatgg
    19981 gagagagtac attccttttt gttcctttct gcggagagca ttatatgtgg gaggacgata
    20041 aatgagtgcc ccatacctga ccatctgcat cctgtgtgtg ttattaggaa ttgcattttt
    20101 gtaccggttt tgtctggtat tccagagcag cagagaagga tatgagacag gagcaagcaa
    20161 gaccatcggc agccgtgaaa tacagatgga ttactataca atagaagaaa atgagaatgg
    20221 gttactggcg gttctggcgg atggaatggg aaaagaagcg ggcggcagga tagcagccaa
    20281 aacggtcatc cgggttttta aagaaatttt tggaacatat aacatggcgg atcacccttc
    20341 ctattttttc agaaaagcat ttcagactgc aaaccgggaa attttaaaac agatggatga
    20401 gggaagagga atggcggcgg tcagcgccgt tatgatacag ggaggatttc tgttttacgg
    20461 gattgtcggg aatgtaaaga ttgcagtatt ccgaaatgag gaactgattc ctcttggaac
    20521 gggacatact gtagatgtgc tggcacagga taagtatgtg gaaggtgttc
//
