LOCUS       c00001_NZ_JAJF..       18866 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAJFOJ010000001.1 Roseburia inulinivorans DSM 16841 strain
            FDAARGOS_1587 ctg.s1.000000F_arrow_pilon, whole genome shotgun
            sequence.
ACCESSION   c00001_NZ_JAJF..
VERSION     c00001_NZ_JAJF..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:59:55
            Original ID  :: NZ_JAJFOJ010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1259502
            Orig. end    :: 1278368
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..966)
                     /locus_tag="ctg1_1147"
                     /transl_table=11
                     /translation="MKQTVKKLLFMLGIMCLTIFGKETSTTVLADNLDEIENYTIYAEP
                     DWEDGSVYLKYDITWKVLDSDTDGPLEWVKIGIPNSNVEEIEGYSSNIENIRYYKNGGS
                     YVRIDFDRKYYEGETVEFSFGIHQHHLYQTIDGMRVYRFTPGWFDEIVVDELNIYWKSD
                     NIKYVLNGYCEQDGYYQFRTSLAEGEKYTVKIEYDADVFQTEDDKKISHPVGTGTKIVM
                     AVMLLVVPGILLLLIIRAYKKGKPVDSYRAESGFGNAFTDIRTSSHYTGGRGSGGCACA
                     CACACAGGGRAGCSKKDFYGTKLTTMAIREALKDTAHEEI"
     protocluster    1..18866
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1268846:1269574]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9345..10072
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..18866
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18866
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="4"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(963..2333)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1148"
                     /sec_met_domain="PF04055 (E-value: 1.7e-20, bitscore: 71.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.2e-07, bitscore: 29.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 6.4e-08, bitscore: 30.2,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLREKIYELKNWKLAVHTTWNPGAENVMRIHLVPPRFLSGKIVPS
                     VVILNGQEIVPVSEAWAILLTEFIRRINEYENHAIEEKEVQQVLKETFGAVRKIYPKTD
                     PEVFHRDLSVMLDTFEDVIAGKIPQMEIAGISLGEYAPYMRAPHRMDLMVSAMTREGKW
                     HCNQKCIHCYAAGQPLSEEQELDTESWKKIIRACRKAGITQLTFTGGEPTLRDDLCKLI
                     SEARWFVTRLNTNGIRLTKELCAELVQAELDSVQVTFYSADPDIHNELVGGAHYEETVA
                     GIRNAVTAGINLSINTPLCSLNKDYLETLKFLHNLGVRYVTCSGLIITGNARTDESVRT
                     QLSGEQLYQVLKEAAGYCYANNMEINFTSPGWIAQEKLQELGLDVPSCGACLSNMAVTP
                     DGKVVPCQSWLSGENFGKMGVTRWEKIWNHPDCKARRMETAQMKQECPLRGKAEMTR"
     PFAM_domain     complement(996..1172)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1148_0088"
                     /evalue="5.20E-07"
                     /label="ctg1_1148"
                     /locus_tag="ctg1_1148"
                     /protein_end="446"
                     /protein_start="387"
                     /score="30.1"
                     /tool="antismash"
                     /translation="CGACLSNMAVTPDGKVVPCQSWLSGENFGKMGVTRWEKIWNHPDC
                     KARRMETAQMKQEC"
     PFAM_domain     complement(1401..1841)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1148_0087"
                     /evalue="1.20E-19"
                     /label="ctg1_1148"
                     /locus_tag="ctg1_1148"
                     /protein_end="311"
                     /protein_start="164"
                     /score="71.4"
                     /tool="antismash"
                     /translation="CNQKCIHCYAAGQPLSEEQELDTESWKKIIRACRKAGITQLTFTG
                     GEPTLRDDLCKLISEARWFVTRLNTNGIRLTKELCAELVQAELDSVQVTFYSADPDIHN
                     ELVGGAHYEETVAGIRNAVTAGINLSINTPLCSLNKDYLETLK"
     CDS             complement(2407..3249)
                     /locus_tag="ctg1_1149"
                     /transl_table=11
                     /translation="MGNFLPKYPKNYFKNQKGLRSFWKMISIGISIIFGILACIDKFEK
                     QWELNVFYFGIALLLFYIFIHPVWMDAKKKKGYKFEEDRIYVFNILGKQTRMIAYQTME
                     KAVQKRQVRCKNNGLVIGKGRNKICFLYEPGSLEAAKRVRQCYDMLQKHIEPALPCFRQ
                     TGQDLLDRRAFYRRCRKRQTILLLIGSFFAGVFCHNSSDPDATVMLIAAVVVGFCETLT
                     LLSLYGTILLEAENEKKITREFKETDYIRAKDARFGKVYTAVVVVCLLLFNAWVIFFS"
     CDS             complement(3353..4006)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 128.2; E-value: 5.7e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1150"
                     /transl_table=11
                     /translation="MKKTTVVFDLDGTLLDTLQDLANAVNYALEKQGMPKRTLEEVRQF
                     VGNGVRLLMIRAVPDGERNPLFEETFALFKEYYGKHCNDNTKPYAGVVELIETLKEKGY
                     AVAIVSNKIDFAVKELNDLYFKGIVPVAIGEKEGIRRKPAPDTVFEALKELGKTKEEAV
                     YVGDSDVDLETAKNSGMPCISVLWGFRDKEFLAEHGAERYAKTAEDVLRFVEEM"
     aSDomain        complement(3452..3769)
                     /aSDomain="TIGR01662"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IIIA: HAD hydrolase, family IIIA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1150_0021"
                     /evalue="4.40E-13"
                     /identifier="TIGR01662"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="185"
                     /protein_start="79"
                     /score="47.5"
                     /tool="antismash"
                     /translation="KHCNDNTKPYAGVVELIETLKEKGYAVAIVSNKIDFAVKELNDLY
                     FKGIVPVAIGEKEGIRRKPAPDTVFEALKELGKTKEEAVYVGDSDVDLETAKNSGMPCI
                     SV"
     PFAM_domain     complement(3452..3991)
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1150_0089"
                     /evalue="3.20E-39"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="185"
                     /protein_start="5"
                     /score="135.0"
                     /tool="antismash"
                     /translation="VVFDLDGTLLDTLQDLANAVNYALEKQGMPKRTLEEVRQFVGNGV
                     RLLMIRAVPDGERNPLFEETFALFKEYYGKHCNDNTKPYAGVVELIETLKEKGYAVAIV
                     SNKIDFAVKELNDLYFKGIVPVAIGEKEGIRRKPAPDTVFEALKELGKTKEEAVYVGDS
                     DVDLETAKNSGMPCISV"
     aSDomain        complement(3458..3778)
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1150_0022"
                     /evalue="5.40E-09"
                     /identifier="TIGR01509"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="183"
                     /protein_start="76"
                     /score="34.4"
                     /tool="antismash"
                     /translation="YYGKHCNDNTKPYAGVVELIETLKEKGYAVAIVSNKIDFAVKELN
                     DLYFKGIVPVAIGEKEGIRRKPAPDTVFEALKELGKTKEEAVYVGDSDVDLETAKNSGM
                     PCI"
     aSDomain        complement(3470..3763)
                     /aSDomain="TIGR01549"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v1: HAD hydrolase, family IA,
                     variant 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1150_0023"
                     /evalue="1.30E-08"
                     /identifier="TIGR01549"
                     /label="ctg1_1150"
                     /locus_tag="ctg1_1150"
                     /protein_end="179"
                     /protein_start="81"
                     /score="33.3"
                     /tool="antismash"
                     /translation="CNDNTKPYAGVVELIETLKEKGYAVAIVSNKIDFAVKELNDLYFK
                     GIVPVAIGEKEGIRRKPAPDTVFEALKELGKTKEEAVYVGDSDVDLETAKNSG"
     CDS             complement(4166..4333)
                     /locus_tag="ctg1_1151"
                     /transl_table=11
                     /translation="MLNIYFGDMEEAIYNPAVYFKNIYQDSWITNERSKAMIIKCLMRQ
                     HVGIIVQNGS"
     CDS             complement(4518..5246)
                     /locus_tag="ctg1_1152"
                     /transl_table=11
                     /translation="MIENAGEDRQIAVQIFIDYIQVPMIIEGETYQTFFVDTDKSFSKE
                     SCFQIAETLDESVDHKIMAAMTVYSDKHVKDSELEYTTNGYSIALDAVLDIAGNTDQLI
                     MNKLYNYENPRESYKDMWYGVLINTELQDFKRRVPNKEIIAQKNERKDFVYHVGGYDDC
                     TEALVILCMGMEQVDVNQQKYMLFKLEKGKIQDGLVTITMPDEQGCYDLTGWIIKNPFS
                     EEKTEINSVSDTWRFTINVT"
     CDS             complement(5350..5991)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 173.6; E-value:
                     8.8e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1153"
                     /transl_table=11
                     /translation="MTDDVVIQVNNVSKKFKSQVVLKDITLQCRTGRIYGFVGYNGSGK
                     TVLFKCICGLLYVDAGEIRVNGEKIGREMIKNAGIIIEEPAFLGNESGRKNLELLYMLR
                     HKRDKKRIADVMQMLGLNSESKKTVRQYSLGMRQRLALAQALMEDPDILILDEPMNGLD
                     RDGVNEIRQLLLKLKEQGKTILLASHNKEDIEVLCDEVFEMEHGKLQQIR"
     PFAM_domain     complement(5512..5928)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1153_0090"
                     /evalue="3.20E-28"
                     /label="ctg1_1153"
                     /locus_tag="ctg1_1153"
                     /protein_end="160"
                     /protein_start="21"
                     /score="99.0"
                     /tool="antismash"
                     /translation="LKDITLQCRTGRIYGFVGYNGSGKTVLFKCICGLLYVDAGEIRVN
                     GEKIGREMIKNAGIIIEEPAFLGNESGRKNLELLYMLRHKRDKKRIADVMQMLGLNSES
                     KKTVRQYSLGMRQRLALAQALMEDPDILILDEPMN"
     CDS             complement(5988..6836)
                     /locus_tag="ctg1_1154"
                     /transl_table=11
                     /translation="MIYGVTGMWGANKLGIIKYRIKNVKIFLIAIIWLFILDVYLADYR
                     SMAMTLGLKDSFAILPHVQNDFYFNKIMLLGGMIFFADIPFMSGEELYVVLKIGKEKWS
                     QINCCYIVLSGVLLSTLLTVLSLLTILPAISLKNEWGTLYQTFAFSGTADCVIINSKAM
                     SYYSPYALMLNIFLIDALTFAFMGMLLYTLSLFVSKIWSYVIVVVLIFLQSVFGKMGLV
                     LDNFLPFSWISASHWRFGYDRHRPDLIYIYTAFCMLLFLLAVISEWKIKRMDWVSKEEH
                     R"
     CDS             complement(6799..7593)
                     /locus_tag="ctg1_1155"
                     /transl_table=11
                     /translation="VKSYLKMDFYRMLTSKYFGIGILGVVGVYGLSLMQLKSQDVYLLN
                     YYIKFYSTYMLLLIFGAVAYSNAMMEDLEYKNYYLQIQKGSFRKYIWSKVITAFISAVI
                     VMVLGTSIFCLMAHFKMPLLSPDNDMLEYLADGDYLSQLITPETIFWYLIADAAMTGLM
                     AGIFSVFAMWLSLFVKNQMFTVMVPIVGFYFFVNYFTRIFGENDYFKLNVIYISNGKIF
                     ETSFSCFCYALFVAVAIAAITGKLIYSKMHNDIWGDRNVGSK"
     CDS             complement(7595..8746)
                     /locus_tag="ctg1_1156"
                     /transl_table=11
                     /translation="MKKKVLIKWIIGCVMLCIMLLVLWKRTHINYDEYSEKTSDMQHDE
                     VEEIRFPDYINEKVSDGLVFDAEVVIGENFDPDNFYVSTARIMKPDEEKWKQFFGVDNT
                     WDYNVYETESRIGDKIEFQTYTDKQENTLYLTSEEALWAKQDMVFIYNVLDTNEYSPQN
                     NGKLFSEKMDLSFESRQDNLRSVLDKMQQIGIDAAELEVHQEYDLNVDKLKEQEEKKIE
                     AGDIEQSEKKESWSTSDEAYYYYLDETTQGLPVFSKRSVNDYSGDERSQIIVCAGNDGI
                     RYLYMKWFFLFDIGDDKVKFAPIDNIKECIKRKYGKTLDENCITVKKMVLGVYPFATDK
                     EKNAVVPVWICFLERKTKGSEYVEKLYVPINAITGEEFYDMEG"
     CDS             complement(8796..9224)
                     /locus_tag="ctg1_1157"
                     /transl_table=11
                     /translation="MRKIKKIFAASTMAAMLMLPTYGAMASSVSFANFTFTTIPYAEKW
                     ERVTSKAKVDNEQNWYLTLTQKSELDSKEVRALAISNDVDPAMHGLNPYPLKSTTTSSG
                     AIKYQKQVTKNRTYSLYVSGNENVSKPHKIVISGRYTS"
     CDS             complement(9345..9926)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1158"
                     /sec_met_domain="AgrB (E-value: 2.7e-30, bitscore: 102.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEKCANTIADWLINCEVVKETDKELYSYAVYSILLSLSPLLLAI
                     GFGIGMGCVGRSVMIIMPFVIIRKFSGGYHTKHAWSCLIWSCLLLVLCMVLSFHIKCGW
                     VLALITVGAAVSLICFSPIDNENRVLSQEECGCYKMITAVLVIIFMLVDALLFVCQLHI
                     YSICISIGIMLSAGLQLPYIFKELRKMLTN"
     PFAM_domain     complement(9387..9911)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1158_0091"
                     /evalue="1.60E-28"
                     /label="ctg1_1158"
                     /locus_tag="ctg1_1158"
                     /protein_end="180"
                     /protein_start="5"
                     /score="99.4"
                     /tool="antismash"
                     /translation="ANTIADWLINCEVVKETDKELYSYAVYSILLSLSPLLLAIGFGIG
                     MGCVGRSVMIIMPFVIIRKFSGGYHTKHAWSCLIWSCLLLVLCMVLSFHIKCGWVLALI
                     TVGAAVSLICFSPIDNENRVLSQEECGCYKMITAVLVIIFMLVDALLFVCQLHIYSICI
                     SIGIMLSAGLQL"
     CDS             complement(9923..10072)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1159"
                     /sec_met_domain="TIGR04223 (E-value: 1.1e-10, bitscore:
                     38.5, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGKLSKAVAKGMVSVLNTFLRADANSAACVITYQPKAPKELARY
                     RRTK"
     aSDomain        complement(9947..10051)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1159_0024"
                     /evalue="2.10E-10"
                     /identifier="TIGR04223"
                     /label="ctg1_1159"
                     /locus_tag="ctg1_1159"
                     /protein_end="42"
                     /protein_start="7"
                     /score="38.5"
                     /tool="antismash"
                     /translation="AVAKGMVSVLNTFLRADANSAACVITYQPKAPKEL"
     CDS             10345..10701
                     /locus_tag="ctg1_1160"
                     /transl_table=11
                     /translation="MEFQYKEMGTRIKVRRKELKIKQAELAEALEISNNHMSSTENGRQ
                     KPSLDTFIGICRCLNVTPDYLLLGTMHAYNIPQDISDKLRLCNQSDIELAKDFIELLVK
                     RNSTNNTKDGYMLS"
     PFAM_domain     10378..10542
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1160_0092"
                     /evalue="3.20E-11"
                     /label="ctg1_1160"
                     /locus_tag="ctg1_1160"
                     /protein_end="66"
                     /protein_start="11"
                     /score="43.2"
                     /tool="antismash"
                     /translation="IKVRRKELKIKQAELAEALEISNNHMSSTENGRQKPSLDTFIGIC
                     RCLNVTPDYL"
     CDS             10879..11586
                     /locus_tag="ctg1_1161"
                     /transl_table=11
                     /translation="MRILICDDDALIVEQLQKYIRNFFEKIGVKCPELVCFSDGESLLA
                     DKGEKDILFLDVEMPGMNGIYVGNELKKRNDNIIIFIVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNMKDAVDLYNTMTIKIPIETKQGVHTLPASSVIAVEAQGRKVVIHTTQRD
                     FESIRNMQYWLELLPKNCFFQTHRSFIINFEHVTDFDRTLVHMADEQFHAYLTKRKYSA
                     FKEAYLLYLDSTR"
     PFAM_domain     10885..11211
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1161_0093"
                     /evalue="4.50E-16"
                     /label="ctg1_1161"
                     /locus_tag="ctg1_1161"
                     /protein_end="111"
                     /protein_start="2"
                     /score="59.1"
                     /tool="antismash"
                     /translation="ILICDDDALIVEQLQKYIRNFFEKIGVKCPELVCFSDGESLLADK
                     GEKDILFLDVEMPGMNGIYVGNELKKRNDNIIIFIVTSYSEYLDEAMRFHVFRYLSKPL
                     DKQRF"
     PFAM_domain     11287..11556
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1161_0094"
                     /evalue="3.60E-15"
                     /label="ctg1_1161"
                     /locus_tag="ctg1_1161"
                     /protein_end="226"
                     /protein_start="136"
                     /score="56.1"
                     /tool="antismash"
                     /translation="VHTLPASSVIAVEAQGRKVVIHTTQRDFESIRNMQYWLELLPKNC
                     FFQTHRSFIINFEHVTDFDRTLVHMADEQFHAYLTKRKYSAFKEA"
     CDS             11592..12899
                     /locus_tag="ctg1_1162"
                     /transl_table=11
                     /translation="MKNAICYFFSFLVEAIILWQYSSNLFSAKRKLLVKLIALCCLYFI
                     LFFCSLFESIWLNVAFYFLLNFIFLVIQFYLNWYTALFHSSILTAVMSMSELIVYGIIK
                     RFAPHFLDNGREFNHLLVFTVFNKLIFFTVIYLLIHFIKKQEKCSRQYDKSIFLLVFIP
                     IASVFVMFTFINIGENATLPPSLDWMITLSAVFLLTANLLMFGINQYHQKKNMEFTEMQ
                     LLLQQESDSARYYEMLHLQNENQRILIHDMKKHLQSIALLNEDNENEKIRAYIDQLMQS
                     SDLLEFSKICDHKILNNILCRYKKVCNDLHIAFHADIRSNTTTFLSDSDVTSLFCNMLD
                     NAVEASNHIKDSYIEITAAQRKHTPFIIITMINSCACNPFSPNGELVSSKPDPQAHGFG
                     IKSIEKIVHNYNGNMQMYYDGETFTFHTIIMLKMKP"
     PFAM_domain     12570..12878
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1162_0095"
                     /evalue="3.10E-22"
                     /label="ctg1_1162"
                     /locus_tag="ctg1_1162"
                     /protein_end="429"
                     /protein_start="326"
                     /score="78.5"
                     /tool="antismash"
                     /translation="SDSDVTSLFCNMLDNAVEASNHIKDSYIEITAAQRKHTPFIIITM
                     INSCACNPFSPNGELVSSKPDPQAHGFGIKSIEKIVHNYNGNMQMYYDGETFTFHTII"
     CDS             complement(12919..13947)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     134.3; E-value: 8.3e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1163"
                     /transl_table=11
                     /translation="MEMVTLGKTGITVNKNGFGALPIQRISTDDAVALARRAYEAGMTF
                     FDTARFYTDSEEKLGEAFEGMREKIYIATKTAAQNAEDFWKDLEVSLHNLRTDYIDIYQ
                     FHNPSFCPKPGDGTGLYEAMLEAKAQGKIRHIGITNHRLAVANEAIDSGLYETLQFPFC
                     YLATEKDLELVKKCKEADMGFIAMKALSGGLINNSAAAYAFEAQYDNVLPIWGVQRRSE
                     LEEFISYIDNPPVMNDEIKALIEHDRNELSGEFCRGCGYCMPCPAGIEINNCARMSLML
                     RRAPSDAQLTPEMQAKMKKIENCLHCNKCKSKCPYGLDTPTLLQKNYEDYKRVLAGEVS
                     VK"
     PFAM_domain     complement(12991..13185)
                     /aSDomain="Fer4_17"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13534.8"
                     /description="4Fe-4S dicluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1163_0097"
                     /evalue="2.10E-11"
                     /label="ctg1_1163"
                     /locus_tag="ctg1_1163"
                     /protein_end="319"
                     /protein_start="254"
                     /score="44.3"
                     /tool="antismash"
                     /translation="FCRGCGYCMPCPAGIEINNCARMSLMLRRAPSDAQLTPEMQAKMK
                     KIENCLHCNKCKSKCPYGLD"
     PFAM_domain     complement(13360..13893)
                     /aSDomain="Aldo_ket_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00248.23"
                     /description="Aldo/keto reductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1163_0096"
                     /evalue="3.60E-32"
                     /label="ctg1_1163"
                     /locus_tag="ctg1_1163"
                     /protein_end="196"
                     /protein_start="18"
                     /score="111.7"
                     /tool="antismash"
                     /translation="GALPIQRISTDDAVALARRAYEAGMTFFDTARFYTDSEEKLGEAF
                     EGMREKIYIATKTAAQNAEDFWKDLEVSLHNLRTDYIDIYQFHNPSFCPKPGDGTGLYE
                     AMLEAKAQGKIRHIGITNHRLAVANEAIDSGLYETLQFPFCYLATEKDLELVKKCKEAD
                     MGFIAMKALSGGLIN"
     CDS             complement(14268..16217)
                     /locus_tag="ctg1_1164"
                     /transl_table=11
                     /translation="MKIRLKFEKTNLIRLIVAMIFAAVLYYKVTFPIYVLAGFGACYFL
                     IKSLEIEINNKWLKLALNVVLLGGSSAMTAYMVQYLLLDAELRARIMDNKMFLNVLCCL
                     VIYLAVQVFTKNVGLTCIISHMALMIFAGINYFVYLFRGNEFIFSDLRSISTGLSVAGN
                     YEFVLDDRAVYVVLLSVLYVAFVRKIHVKFEKRLWMAVVCISIAVFCCAYIETETEGTV
                     TETWEQKGSYRNGYILNYVLSIRDCFIAEPDGYSEEVVTELENQYSGDGESYVNQNIEK
                     KPTIIVVMSESYADLSVVGDFLTNEQVTPYYDSLQDNIMKGHALSSVFGAKTPNSEWEF
                     MTGNSMAFLPSGSVVYQQYISDTPTSIVSNLKNIGYTCVAMHPYYETGWSRNAVYPTMG
                     FDETHFIDDFDQTKLLRKYITDQELYESIVERYESKKSNEDLFIMSISMQNHGGYTEKY
                     PNFNEQIRTLGASYSDANQYLSLLHESDKALEYLISYFQSVDDPVEIVFFGDHQPSLNT
                     NFYKGLNGKGLSGLTEDELENLYTVPFFIWTNYETETEEVPITSLNYLSTMALERAGIA
                     LPSYNQFLADMQQTIPAINSRGYYSVSSGCFKHLEEAVGEEAEWIDRYQILQYNNMFDK
                     KKQSKVFFPYLQNQ"
     PFAM_domain     complement(14496..15371)
                     /aSDomain="Sulfatase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00884.25"
                     /description="Sulfatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1164_0098"
                     /evalue="2.90E-25"
                     /label="ctg1_1164"
                     /locus_tag="ctg1_1164"
                     /protein_end="574"
                     /protein_start="282"
                     /score="89.4"
                     /tool="antismash"
                     /translation="PTIIVVMSESYADLSVVGDFLTNEQVTPYYDSLQDNIMKGHALSS
                     VFGAKTPNSEWEFMTGNSMAFLPSGSVVYQQYISDTPTSIVSNLKNIGYTCVAMHPYYE
                     TGWSRNAVYPTMGFDETHFIDDFDQTKLLRKYITDQELYESIVERYESKKSNEDLFIMS
                     ISMQNHGGYTEKYPNFNEQIRTLGASYSDANQYLSLLHESDKALEYLISYFQSVDDPVE
                     IVFFGDHQPSLNTNFYKGLNGKGLSGLTEDELENLYTVPFFIWTNYETETEEVPITSLN
                     YLSTMALERAG"
     CDS             complement(16452..17432)
                     /locus_tag="ctg1_1165"
                     /transl_table=11
                     /translation="LKWLFVILIIGAIVYTFRDTAGPILEQLKETTPSVLAGICVMSGI
                     YCLVEALITTVLAKQYNPDFRYQWGIENMFFCSFYRVATLGSGSGVAAIIYLNEHGVDY
                     SKGFGMYMLQYAFHKISIAIYSAIFFFLSWNYMCGHFGGYTWLLLAGYAITMVITLALI
                     LFCCSTKFHQLIFAMLDFFNKKGKYDALEHQLREQCADLETASKYLLHKKKMVAGVVGL
                     NLLKLCFWYGMPYLLFAGDKNINMVETMAITALSVMLAAVIPAPAGIGSTEFVFTGLFA
                     GIVGTGIAGSASLLYRFATFVFPFLIGVAVVITRKIRERRAMENL"
     PFAM_domain     complement(16509..17414)
                     /aSDomain="LPG_synthase_TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03706.15"
                     /description="Lysylphosphatidylglycerol synthase TM region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1165_0099"
                     /evalue="1.20E-24"
                     /label="ctg1_1165"
                     /locus_tag="ctg1_1165"
                     /protein_end="308"
                     /protein_start="6"
                     /score="87.6"
                     /tool="antismash"
                     /translation="ILIIGAIVYTFRDTAGPILEQLKETTPSVLAGICVMSGIYCLVEA
                     LITTVLAKQYNPDFRYQWGIENMFFCSFYRVATLGSGSGVAAIIYLNEHGVDYSKGFGM
                     YMLQYAFHKISIAIYSAIFFFLSWNYMCGHFGGYTWLLLAGYAITMVITLALILFCCST
                     KFHQLIFAMLDFFNKKGKYDALEHQLREQCADLETASKYLLHKKKMVAGVVGLNLLKLC
                     FWYGMPYLLFAGDKNINMVETMAITALSVMLAAVIPAPAGIGSTEFVFTGLFAGIVGTG
                     IAGSASLLYRFATFVFPFLIG"
     CDS             complement(17469..18866)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1166"
                     /sec_met_domain="PF04055 (E-value: 6.1e-15, bitscore: 53.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 7e-06, bitscore: 23.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLVETMERKAFGVAVDATLKNLNKDREKALLQIVDLTEKFMGN
                     NFSKEAYDGARAMIKNPDHKWMRYVNRLLDETDPHVAKMTALNLGFQAAFLGTKTIRKM
                     REVHNCNIPWLILMDPTSACNLHCTGCWAAEYGNKLNLTFDEMDSIVTQGKELGIYFYM
                     MTGGEPLVRKADIIRLCEKHNECAFHCYTNGTLVDQAFCDEMKRVGNLSLSISLEGFED
                     ANDFRRGAGVYDKVLHAMDLLHENGLIFGNSVCYTRKNMDAVTSDEFFDLLIEHGSRFA
                     WYFHLMPVGMKAAPELMPTAEQREYIYHRIREVRAKEGGKEIFVMDFQNDGEFVGGCIA
                     GGRNYCHINPKGDVEPCVFIHYSGANIREKSLLECLKQPLFMAYRDGQPFNDNMLRPCP
                     MLENPELLQKMVHETGAHSTDVEEAEPVEHLCGKCEAYACEWKKTADKLWEEHPYHQKG
                     YTNFKKK"
     PFAM_domain     complement(17673..17855)
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1166_0101"
                     /evalue="5.30E-05"
                     /label="ctg1_1166"
                     /locus_tag="ctg1_1166"
                     /protein_end="398"
                     /protein_start="337"
                     /score="23.7"
                     /tool="antismash"
                     /translation="CIAGGRNYCHINPKGDVEPCVFIHYSGANIREKSLLECLKQPLFM
                     AYRDGQPFNDNMLRPC"
     PFAM_domain     complement(18120..18509)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1166_0100"
                     /evalue="3.40E-14"
                     /label="ctg1_1166"
                     /locus_tag="ctg1_1166"
                     /protein_end="249"
                     /protein_start="119"
                     /score="53.6"
                     /tool="antismash"
                     /translation="PTSACNLHCTGCWAAEYGNKLNLTFDEMDSIVTQGKELGIYFYMM
                     TGGEPLVRKADIIRLCEKHNECAFHCYTNGTLVDQAFCDEMKRVGNLSLSISLEGFEDA
                     NDFRRGAGVYDKVLHAMDLLHENGLI"
ORIGIN
        1 ttatatttcc tcatgtgcgg tgtctttcaa cgcctcgcgg attgccattg tcgtaagctt
       61 tgttccgtaa aaatcttttt tcgagcatcc ggctctcccg cctccggcac aggcacacgc
      121 acatgcgcag gcacagccac cactacctct gccgcctgtg taatggctgc tcgttctgat
      181 atcagtaaac gcattgccaa atccgctctc cgctctgtaa gaatccaccg gtttgccttt
      241 tttgtacgcc cggatgataa gtaaaagcaa aatgcccggc actacaagaa gcataaccgc
      301 cattacaatt tttgtacctg ttccaaccgg atgcgaaatc ttcttgtcgt cttccgtctg
      361 aaatacatct gcatcatatt ctatttttac agtgtatttc tccccctccg ccaaagacgt
      421 gcgaaactga tagtaaccat cctgttcaca atatccattt aaaacatatt ttatattgtc
      481 agatttccaa tagatattca gttcatctac aacaatctca tcaaaccagc ccggcgtaaa
      541 tcgatacact ctcatgccat ctatagtctg gtatagatga tgctggtgga ttccaaatga
      601 aaattctacc gtctcaccct cgtaatattt ccggtcaaaa tcaatcctta cataggaacc
      661 gccatttttg taataccgaa tattttcaat attactgctg taaccctcaa tctcctctac
      721 attcgaattt gggataccga ttttaaccca ttccagagga ccgtctgtgt cgctatccaa
      781 cactttccac gtaatatcat atttcagata aacagagccg tcttcccagt ctggttctgc
      841 gtaaatcgtg taattttcaa tctcatccaa attgtccgcc aaaacggttg tcgatgtctc
      901 ttttccgaat atggtcaaac acatgatacc aagcataaac aataattttt tcaccgtctg
      961 tttcatcttg tcatctccgc ctttcccctt aatgggcact cctgtttcat ctgtgcggtt
     1021 tccatgcggc gcgctttaca gtctggatga ttccagatct tttcccagcg tgtcactccc
     1081 atttttccaa agttttctcc cgataaccag ctctggcacg gaactacttt tccgtctggt
     1141 gtgactgcca tgttacttaa acatgcacca caggacggta catccagtcc aagctcctgc
     1201 agcttttcct gcgcgatcca gcccggcgat gtaaagttga tttccatatt gtttgcataa
     1261 caatatccgg ctgcttcttt taacacctga taaagctgtt cccctgaaag ctgtgtccgt
     1321 accgattcat ccgttcttgc atttcccgtg atgatcagtc ccgaacaggt cacatatcgc
     1381 acacccagat tatgtaaaaa tttcagtgtt tccagataat ctttgttcaa actgcaaagc
     1441 ggtgtgttaa tactcagatt gattcctgct gtcaccgcat ttctaattcc agcaacagtt
     1501 tcctcataat gtgcaccgcc aacaagttca ttatgaatat ccggatctgc cgaataaaat
     1561 gtcacctgca cactgtcaag ttccgcctgt acaagttctg cgcaaagctc ctttgtcagc
     1621 cgtatcccat ttgtgtttaa ccttgttaca aaccatcttg cctctgaaat taatttacat
     1681 aaatcatctc taagtgtagg ttctccaccc gtaaaggtca attgggtaat tcctgctttc
     1741 ctgcatgcac ggatgatctt tttccagctt tcagtgtcaa gctcctgttc ttctgacagc
     1801 ggttgtcctg ccgcatagca gtgtatgcat ttttgattgc aatgccattt tccttcgcgt
     1861 gtcatggcag aaaccataag atccatccgg tgtggtgccc gcatatacgg tgcatattcc
     1921 ccaagactta ttcctgcgat ctccatctgt ggaatttttc cagcgatcac atcctcaaat
     1981 gtatccagca tgaccgacaa gtctctgtga aaaacttctg ggtctgtttt cggatatatc
     2041 tttctgaccg ctccaaaggt ttccttaaga acctgctgca cctccttctc ctctatcgca
     2101 tgattttcat attcattgat ccgccggata aactctgtga gaagaatcgc ccatgcctca
     2161 ctgaccggta cgatttcctg cccattcaat atcacaacag aaggcactat ttttcccgac
     2221 agaaagcgtg gtggaacaag gtgaatccgc atcacatttt ccgcgcccgg attccacgtt
     2281 gtgtgaaccg ccaatttcca atttttcaat tcatatattt tttcccgcag catattcact
     2341 catccccgca gcctgtcaga tattttttct tccagacctt tacacattat tttctatgta
     2401 ctgtttttat gaaaagaaaa taacccatgc attaaacaaa agcagacaga cgaccacaac
     2461 ggctgtgtat actttgccaa aacgcgcatc tttcgccctg atataatctg tctctttgaa
     2521 ttctcttgta atttttttct cattttctgc ttccagaaga attgttccat atagactgag
     2581 cagtgtcagc gtttcacaaa atcccacgac aaccgctgcg atcagcatca ccgttgcatc
     2641 cggatcagaa ctgttatggc agaatacgcc tgcaaaaaag ctgccgatca acagcaatat
     2701 cgtctgacgt ttcctgcatc tccgataaaa agctctgcgg tctaacaaat cctgtcctgt
     2761 ctgcctgaaa cacggcaatg ctggctcaat gtgtttctga agcatgtcgt aacactgtct
     2821 tacccgcttt gctgcttcca gacttcccgg ctcgtataaa aaacagattt tatttcttcc
     2881 ttttccgatt acaagaccgt tgtttttaca acggacctgc cgtttttgaa ccgctttttc
     2941 catcgtctga tatgcgatca ttctggtttg ttttcccaga atattaaaaa cataaatcct
     3001 gtcttcctca aacttatagc cttttttctt ttttgcatcc atccagaccg gatgaataaa
     3061 aatgtaaaac agcagtaaag caatcccaaa gtaaaacacg tttaattccc actgtttttc
     3121 aaatttatca atacatgcta atattccaaa aatgatgctg attccaatgg agatcatttt
     3181 ccagaagctt cttaaccctt tttgattttt gaaataattt tttggatatt ttggaagaaa
     3241 atttcccatt ctgctttact ccccattatg atgcgcaaac tttcctcgca aatatgcagt
     3301 ttgccgaatc gatgcacact tctaccgagt cactgcacaa tctgccaaac ctctacattt
     3361 cttctacaaa ccgcagcaca tcctctgcgg tctttgcata acgctctgcc ccatgctctg
     3421 ccaaaaattc tttgtcacga aagccccata atacggaaat acatggcatg ccggaatttt
     3481 ttgcagtctc taaatccaca tcagaatcac caacgtaaac cgcttcttcc ttcgtttttc
     3541 caagttcctt caatgcctca aaaacagtat ccggagccgg ttttctgcgg atgccctctt
     3601 tttcaccgat tgctacagga acaattcctt taaaataaag gtcgtttaat tctttgactg
     3661 caaaatcaat cttattcgat acgattgcta ctgcatagcc tttttccttt aacgtctcga
     3721 tcagttctac aacgcctgca tacggctttg tattatcatt gcaatgtttg ccgtaatatt
     3781 ctttaaaaag cgcaaaggtt tcctcaaata atggatttct ctccccatcc ggcaccgccc
     3841 ggatcattag cagacgcacg ccatttccta caaattgacg cacttcctct aatgtacgct
     3901 ttggcattcc ctgcttttcc agtgcataat tgactgcatt tgcaagatct tgtaaagtat
     3961 ctaataatgt tccgtctaaa tcaaaaacta cagttgtctt tttcatggtt atcctcctat
     4021 cgtacaaaca ttccagcaat cacaacaagc tcttccatat tatgaacgat ctcatctgta
     4081 tttaaaatgt ggattgtaaa ctcttgctct ccaaaatcca tcagatgtct taaattaatt
     4141 gtgatatctt tttcttcccc aatttctaag agccattttg cacaattatc cccacatgtt
     4201 gacgcattaa acacttgatt atcatcgctt ttgaacgctc gtttgtaatc caactatcct
     4261 gataaatatt tttaaaataa acagccggat tataaattgc ttcttccata tccccaaaat
     4321 aaatatttag catttataat atgcctccag ttccgacact tgccaaaaat gtatccctga
     4381 tgtatctttg attatacgaa aaatattatg cttcttcaat aaattcattt tattatgtat
     4441 tatttttttg tttgaaaaaa ctctctaacg aaaaattatc cagaccaaag gtctggataa
     4501 ttttttagtg tagtcaatta tgtcacattg attgtaaatc tccacgtatc actcactgaa
     4561 ttgatttctg ttttttcttc tgaaaatgga ttcttaataa tccatcctgt caaatcgtag
     4621 cacccttgct catccggcat tgtaattgtt actaatccat cttgtatctt tcctttttcc
     4681 agcttgaaaa gcatatattt ttgttgatta acatcaactt gttccatacc catgcataaa
     4741 ataaccagtg cttctgtaca atcatcatat ccgccaacat gatacacaaa gtcctttctt
     4801 tcattttttt gtgcaattat ttctttgttt ggtactcttc ttttgaaatc ctgtaattca
     4861 gtatttatca gcactccata ccacatatct ttatatgatt ccctgggatt ctcgtaattg
     4921 taaagtttat tcataattaa ttggtctgta tttcctgcta tatctaaaac tgcatcaagt
     4981 gctatagaat atccattcgt agtatattca agttctgaat ctttcacatg cttatcagaa
     5041 tatactgtca ttgcagccat aattttatga tcaacactct catccagagt ctccgctatt
     5101 tgaaaacaag attcttttga aaaactttta tcagtatcca caaaaaatgt ctgatacgtt
     5161 tctccctcaa ttatcatcgg cacctggata taatcaataa aaatttgtac tgcaatctgc
     5221 ctgtcctccc cggcattttc aatcataaag tacaaattat cgttgccatt atttacagaa
     5281 atttttgaat cattattttt tttatctcct gattttgaat atacatagta tctttttttt
     5341 cattattaat caccgaattt gctgcagttt tccatgttcc atttcaaata cttcatcgca
     5401 taaaacttct atgtcttctt tgttatgact tgcaagtaat attgtttttc cctgttcttt
     5461 cagtttcaat aataactgac gtatttcgtt tactccatcc ctatccagtc cattcattgg
     5521 ctcatccaga atcaatatat ccggatcttc cattaatgcc tgggctaatg caagcctttg
     5581 tctcattccc aacgaatact gtctcactgt ctttttagat tctgaattta atccgagcat
     5641 ctgcataaca tctgcaatcc tttttttatc gcgtttatgc cttaacatat acaatagctc
     5701 aagatttttc cttccggatt catttccaag gaatgccggt tcttcaataa taatccctgc
     5761 gttttttatc atttcacgtc caattttttc tccgttgact ctgatctctc ctgcatctac
     5821 ataaagtaac ccacatatac atttaaaaag aactgttttc ccagatccat tgtatcctac
     5881 aaatccataa atcctacctg ttctgcattg caatgttata tctttgagca caacttgcga
     5941 tttaaatttc tttgacacat tattaacttg tattacaaca tcatctgtca tctatgttcc
     6001 tccttactca cccagtccat tctttttatt ttccattcac tgattacagc cagtagaaat
     6061 aataacatac aaaacgccgt gtaaatgtaa ataaggtccg gtctgtgcct gtcatatcca
     6121 aatctccaat gcgaagcaga tatccatgaa aatggcagga aattatccaa cactaacccc
     6181 atttttccaa aaacagattg caaaaaaatt aaaacaacaa caattacata tgaccatatt
     6241 ttcgacacaa ataaactcaa tgtatatagc agcattccca tgaatgcaaa ggttaacgca
     6301 tcaatcagaa aaatattcag cattaacgca taaggtgaat aataactcat tgcctttgaa
     6361 tttataatca cacaatctgc cgttcctgaa aaagcaaatg tctgataaag cgttccccat
     6421 tcatttttta aactaattgc aggtaaaatt gtcaacaagc taagcaccgt aagcaatgtg
     6481 cttagtaata caccactcaa gacgatataa cagcaattaa tctgtgacca cttttctttc
     6541 ccaatcttaa gcactacata aagttcttct cctgacataa agggaatatc tgcaaaaaaa
     6601 atcatgccac caagcaacat aattttgtta aaataaaaat cattctggac atgtggcaat
     6661 attgcaaaac tatcttttaa ccctaatgtc attgccattg atctgtaatc agccaaatat
     6721 acatccaata taaacaacca gataatggca atcagaaata tttttacatt ttttattcta
     6781 tattttataa tacctaattt atttgctccc cacattcctg tcaccccata tatcattatg
     6841 cattttacta tatattaact ttcctgttat tgctgcaatt gcaactgcga cgaacagtgc
     6901 ataacaaaaa caactaaagg atgtttcaaa tatttttcca tttgatatat agatcacatt
     6961 caacttaaaa taatcattct ctccaaatat tcttgtaaaa taattgacaa aaaagtaaaa
     7021 ccctactata ggaaccataa ctgtaaacat ttgatttttt acgaataaag acaaccacat
     7081 agcgaataca gaaaaaatgc cagccattag ccctgtcatt gccgcatccg ctatcagata
     7141 ccaaaatatt gtttctggcg taataagctg actcagataa tcaccatcag caagatattc
     7201 cagcatatca ttatccgggg acaagagcgg cattttaaaa tgagccatta agcaaaaaat
     7261 ggatgttcca agtaccatca cgataacagc tgagataaat gccgtaatta ctttagacca
     7321 aatatatttt ctaaaacttc ccttttgtat ctgcaaatag tagtttttat actccaaatc
     7381 ctccatcatg gcattagaat atgcaacagc gccaaatatc agcaaaagca tatatgtact
     7441 atagaattta atataataat ttagcaaata tacatcctga ctttttaact gcatcagtga
     7501 aagtccatat acaccaacaa cacctaatat tccaattcca aaatacttcg atgttaacat
     7561 acgataaaaa tccattttca aatatgactt cacattaccc ctccatatcg taaaattcct
     7621 ctcctgtaat cgcattaatc ggaacatata atttttctac atactcactg ccttttgttt
     7681 ttcgctctaa aaaacatatc cagaccggaa caactgcatt tttctcctta tcagttgcga
     7741 atggataaac tcccaatacc atttttttta cagtaataca gttctcatct aacgtttttc
     7801 catattttct tttgatgcat tctttaatgt tgtcaattgg tgcaaatttt accttgtcat
     7861 cccctatatc aaataaaaaa aaccatttca tatacagata acgtattcca tcatttccag
     7921 cacacacaat aatctgtgat cgttcatccc ctgaataatc atttacactt cttttagaaa
     7981 aaaccgggag tccctgtgtc gtttcgtcca gataataata atatgcctca tccgaagttg
     8041 accatgactc ttttttctca ctttgttcta tgtcccctgc ttcaatcttt ttttcttcct
     8101 gttcctttaa cttatctaca tttaaatcat attcctggtg aacttccagc tccgctgcat
     8161 ctattcctat ttgctgcatt ttatctaaaa cggaacgtaa attatcttgt ctgctttcaa
     8221 aagagagatc catcttttca gaaaaaagct ttccattatt ttgtggacta tactcatttg
     8281 tatccagaac attataaata aataccatat cctgctttgc ccacaatgct tcctctgatg
     8341 ttaaatacaa agtattttcc tgtttatctg tatacgtctg aaattcgatt ttatccccta
     8401 tacggctttc tgtttcataa acattataat cccacgtatt atctacccca aaaaactgct
     8461 tccatttttc ttcatccggt ttcataatcc ttgccgtact cacataaaaa ttatcaggat
     8521 caaaattttc tccaattaca acctctgcat caaacaccag gccgtcactc actttttcat
     8581 tgatataatc aggaaatctg atttcttcta cctcatcatg ttgcatatca gaagtttttt
     8641 ctgaatactc atcataattt atatgcgtcc ttttccataa taccagtaac attatacaga
     8701 gcattacaca gccaatgatc cattttataa gcactttctt tttcataaat ctcctttttc
     8761 acaacaccga agtcaatcag actccggtgt ttttattatg acgtatatct tcccgaaatt
     8821 acaattttat gaggtttact tacgttttca tttccactga cataaagaga atatgtccta
     8881 ttctttgtaa cttgtttttg atattttata gctccactcg acgtcgttgt cgatttcagt
     8941 ggatatggat tgagtccatg cattgccgga tcaacatcat ttgatatagc caaagccctt
     9001 acttcttttg aatccaactc actcttttgt gttaaagtaa gataccaatt ctgttcattg
     9061 tcaactttcg cttttgaagt cactctttcc catttttctg catatggtat agttgtaaat
     9121 gtaaagttag caaatgaaac actggatgcc attgccccat atgttggcaa catcaacata
     9181 gcagccattg tgcttgcggc aaaaattttt tttatttttc tcatataagc aattctccct
     9241 tctactacta aatcctcgtg aaatcaatga caacttcatt atctcttata ttgtcatgat
     9301 ttcaatacgt tctgcgccaa acgacatttt ttgcctttat ttggtcaatt cgtcaacatt
     9361 tttctcaatt ctttgaaaat gtagggaagc tgtaaccctg cagacaacat aataccaatt
     9421 gaaatacata ttgaatatat atgtaactgg cacacaaaaa gcaacgcatc tacaagcata
     9481 aatattatta caagcacagc tgttatcatt ttataacaac cacattcttc ttggctcaac
     9541 actctgttct cattgtcaat cggactaaaa caaatcaggc ttacagctgc tcctacagta
     9601 atcaatgcaa gtacccatcc acatttgatg tgaaatgaca ataccatgca caatactaat
     9661 agcaggcatg accatatcag acacgaccat gcgtgttttg tatggtatcc tccgctaaac
     9721 ttccggatta ttacaaatgg catgattatc atgacgcttc gcccgacaca tcccatacca
     9781 atcccaaatc ctatggctag caacaacgga gatagcgaca aaagaatact atacacagca
     9841 taactgtata attctttatc tgtttccttt acaacctcac aatttatcag ccagtctgct
     9901 attgtatttg cgcatttctc aatcatttcg ttctcctgta tcttgctaat tcttttggtg
     9961 ctttgggttg atatgtaata acacatgccg ctgaatttgc atcagcacgc agaaatgtat
    10021 tcaaaactga taccattccc tttgcaaccg cttttgataa cttacctttc attgcaagtt
    10081 cctcctctct ccagattatc attgatattc acaggaacta taataaacga ttttccttct
    10141 ataaacgagt cctttggtat aaacagaaca attctttgca attttgggat aaaataaaac
    10201 ttttcacgca caaaatatat gtgatacaga aaacattatg caataaatta attaaattat
    10261 atgtaacacg gaatatttct gtatcacatt cttcgttctt gctgtttcta ttgataagat
    10321 acaataagaa agaaggtaat tcatatggaa tttcagtata aagaaatggg aactcgcata
    10381 aaagtacgcc gaaaggaatt gaaaataaaa caggcagaat tagcagaggc tcttgaaata
    10441 tcaaacaatc atatgtcctc cacagaaaac ggaaggcaga agccaagtct ggataccttt
    10501 atcggtattt gcagatgcct taatgttacg cccgattatc ttttgcttgg aacaatgcac
    10561 gcatataaca ttccacaaga tatttcagat aaattacgtc tatgcaatca gtccgatata
    10621 gaacttgcca aagattttat tgaacttctt gtaaaaagaa atagcacaaa caataccaaa
    10681 gacggctata tgctttcata attttgcatt tcccgcattc ttagcattct atgcgggaat
    10741 ttctcttact tttttccatt ttttaacttc aagcccaaaa tccactaaaa aatgtctttt
    10801 catacagttt ttttgtattt tcctaacctt tattgtataa tgtagaggaa attatacgtt
    10861 gtaaatggag tgaaaaagat gcgaatactc atctgtgacg atgatgctct gatagtcgaa
    10921 cagcttcaga aatatataag aaattttttt gaaaaaatcg gtgtgaaatg tcctgaactg
    10981 gtctgttttt ctgacgggga atctctactg gcagacaaag gtgaaaaaga cattcttttt
    11041 cttgatgtag aaatgcccgg aatgaatggc atctatgtgg gaaatgaatt aaaaaaaaga
    11101 aatgataata tcattatttt tattgtgact tcttattccg aatatcttga tgaagcaatg
    11161 cgttttcacg tatttcggta tctgtcaaag cctttggata aacagcggtt tttccgtaat
    11221 atgaaagatg ctgtcgacct gtataatacc atgacaatca aaattcccat tgaaacaaaa
    11281 cagggtgtac atacgcttcc cgcatcctct gtcatagcag tggaggcaca gggaagaaaa
    11341 gtagtgatac atacaactca gcgtgatttt gaatccatcc gcaatatgca gtattggctg
    11401 gagcttcttc ccaaaaactg ctttttccag acacaccgca gtttcattat caattttgaa
    11461 catgtcacag attttgaccg tactcttgtt cacatggcgg atgaacaatt ccatgcctat
    11521 ctgacaaaaa ggaaatacag cgcatttaaa gaagcctatc ttctttattt agatagtacg
    11581 aggtaaacca gatgaaaaat gctatttgtt attttttcag ttttcttgta gaagcaatta
    11641 tactttggca atattcctcc aatctgtttt ctgccaaacg caaactcttg gtaaaactta
    11701 tcgcactatg ctgcttatat tttatcctgt ttttttgttc gctgtttgaa tctatatggt
    11761 taaatgtagc tttctatttt ttgttgaatt tcattttctt agttatccag ttttatctaa
    11821 attggtacac agcattattt cattcatcta tcctgacagc agttatgtcc atgagcgagt
    11881 tgatagtata tggaattatc aagcggtttg ctcctcattt ccttgataat ggtagggaat
    11941 ttaatcatct tttggttttt acagtcttta ataaacttat attttttact gttatatatc
    12001 tcctcattca ttttataaaa aagcaggaaa aatgcagtcg gcagtatgat aagtccatat
    12061 ttttgcttgt tttcatccct atagcctctg tctttgttat gttcacgttt ataaatattg
    12121 gagaaaacgc cacccttcca ccatctcttg actggatgat tacattgagt gctgtttttc
    12181 tactgacagc taatctgctt atgttcggaa tcaatcagta tcatcaaaaa aaaaatatgg
    12241 aatttacaga aatgcagtta ttgctccaac aagagtcgga ttcagcgagg tattatgaaa
    12301 tgttacatct gcagaacgaa aatcagcgta ttttaatcca tgatatgaaa aaacatcttc
    12361 aatccattgc actgttaaat gaagataacg agaatgaaaa aatcagagct tacattgatc
    12421 aactaatgca gtcctctgat ttattggaat tttctaagat atgtgatcac aaaatattaa
    12481 ataatatttt gtgccgctat aaaaaagtgt gtaatgatct gcatattgca tttcacgcag
    12541 atatccgcag taataccact actttcctct ctgattcaga tgttacttct ctattctgta
    12601 acatgctgga taatgcggtg gaggcttcaa atcatatcaa ggattcctat attgaaatca
    12661 ctgctgctca aagaaaacat accccattta tcattattac aatgattaac tcatgtgcct
    12721 gcaatccgtt ctctccaaat ggggaacttg tttcttccaa acctgaccca caggcacatg
    12781 gctttggtat taagagcata gaaaaaattg ttcataacta taacggaaat atgcagatgt
    12841 actatgatgg tgaaaccttc acttttcaca cgattattat gttgaaaatg aagccatagt
    12901 ttacaattac agattttttt atttcacgct cacttcaccg gcaagcactc tcttgtagtc
    12961 ctcataattc ttctgtaaca aagttggggt atcaagtcca tacggacatt tgctcttaca
    13021 tttgttgcaa tgtaggcaat tctcaatctt cttcattttc gcctgcattt ccggtgtgag
    13081 ctgtgcatcc gatggtgcgc ggcgcagcat aagtgacatt ctcgcacagt tattgatctc
    13141 gattcctgcc ggacatggca tacaataacc acatccacga cagaattccc cgcttaattc
    13201 gtttctgtca tgctcgatga gcgctttgat ctcatcattc atcaccggag gattgtcgat
    13261 ataggaaata aattcttcca gttctgatct tctctggaca ccccagatag gaagtacatt
    13321 atcatactgt gcctcaaatg cataagctgc tgccgaatta ttgatcagtc caccggaaag
    13381 tgccttcatc gcaataaagc ccatatccgc ttctttgcac tttttcacaa gttccagatc
    13441 cttttctgtc gcaagatagc agaatggaaa ctgtaatgtc tcatacagac cagaatcaat
    13501 tgcctcattt gccactgcca gtctgtggtt tgtaattccg atatggcgta tttttccctg
    13561 cgcttttgcc tccaacatcg cttcatacaa tccggtgcca tcccccggct tcgggcagaa
    13621 agatggattg tggaactgat aaatatcaat gtagtccgtt cttaaattat gcagggaaac
    13681 ctctaaatct ttccagaagt cctccgcatt ctgggcagcc gtttttgtgg caatgtaaat
    13741 cttttccctc atgccctcaa atgcttcccc cagcttttcc tcactgtccg tataaaatct
    13801 tgccgtatca aaaaaagtca tgccagcttc atatgccctt ctcgcaagtg caactgcatc
    13861 atctgtgctg atcctctgta tcgggagtgc cccgaatcca ttcttattga ccgtgatccc
    13921 ggtctttcca agtgttacca tttccattct tctgtatctc cttacctgtc tatcgtcttg
    13981 taggtgtttg ccatcatctt ttctttccca gtataccacc tatcatttca ttgtgaaact
    14041 tatatataac gtaaattaga ttgtgacaaa ttgacaagag caaaagaaaa cactagggag
    14101 ccgccggttc ttagaaagca gcaatcgtgt ttcgttctga tttatcagat aagaaatacg
    14161 actgctgctt tcttagtacc gctgcgagcg acatgtagcg aaagcgtgtt ttcgttgatc
    14221 ttgttaattt gtcacaatct tcaataccta aatttatatt tcttccatta ttgattttgt
    14281 aaatatggaa agaaaacctt actctgcttc tttttgtcga acatattgtt atactgcaaa
    14341 atctgatacc gatcgatcca ctcagcctct tctcccactg cctcttccaa atgcttaaaa
    14401 cagccactgg aaacagaata gtatcccctc gaattgattg caggaatcgt ctgctgcata
    14461 tccgccaaaa actgattgta agacggaagt gcgatcccgg cgcgctccag cgccatggtg
    14521 gagaggtaat tcaggcttgt gatcggaact tcctctgtct ctgtctcata gttcgtccag
    14581 atgaagaacg gcacagtata aagattctcc agttcatcct ctgtcagccc cgacaaacct
    14641 tttccgttca gccctttgta aaaattcgtg ttcagactcg gctggtgatc cccgaaaaag
    14701 acgatctcca ccggatcatc cacgctctgg aaatagctga tgagatattc cagcgcctta
    14761 tcgctctcat gaagcaacga tagatactga ttcgcatcgg aataacttgc tccgagtgtc
    14821 cggatctgct cattaaaatt cgggtatttt tccgtgtaac cgccatggtt ctgcatggaa
    14881 atactcatga taaacaggtc ttcattcgac tttttactct cataccgctc tacaatgctc
    14941 tcgtaaagct cctggtcggt aatatatttc cgcaacagtt ttgtctggtc aaaatcatct
    15001 ataaaatgcg tctcgtcaaa tcccatagtc ggataaaccg cattgcggct ccatcccgtt
    15061 tcatagtaag gatgcatcgc cacacaggta taaccgatat ttttcagatt cgagacaatg
    15121 gatgtcggtg tgtcgctgat atactgctga tacacgacag aaccactcgg cagaaatgcc
    15181 atggaatttc cggtcataaa ctcccattca gagtttggcg ttttcgcacc aaaaacggag
    15241 gaaagggcat gtcccttcat gatattgtcc tgcagggaat cataatacgg tgtcacctgt
    15301 tcattcgtca gaaaatctcc caccacggaa agatccgcat acgattcact catcaccaca
    15361 atgatcgtcg gtttcttctc tatattttgg tttacataac tttctccatc gccgctatac
    15421 tggttttcaa gttctgtcac cacttcctcg gaatatccgt ccggctccgc aataaagcag
    15481 tcacggatac tcaacacata attcaagata taaccgttgc ggtagcttcc tttctgctcc
    15541 cacgtctcag tcacagtgcc ttctgtctcg gtttcaatat aagcacaaca gaataccgca
    15601 atggaaatac ataccactgc catccacagc cttttttcaa atttcacatg gattttccgc
    15661 acgaatgcca cataaagtac cgacagcagt accacgtaaa ctgctctgtc atccagcaca
    15721 aactcataat ttccagccac acttaatccg gtggaaatag aacgaagatc actgaaaata
    15781 aattcatttc cacggaacag atagacaaaa tagttgatcc ccgcaaaaat catcagtgcc
    15841 atatgagaaa taatgcaggt cagacccaca tttttcgtaa acacctgaac cgccagatat
    15901 atcaccagac agcacaggac gttcaaaaac attttgttgt ccatgatcct tgcccgaagt
    15961 tccgcatcca gcaaaagata ctgtaccata taagcagtca tcgcactgct gccgccaagc
    16021 agtaccacgt tcaatgccag ttttaaccat ttattgttaa tttcaatttc cagacttttg
    16081 atcaggaaat agcaggctcc aaaacctgcc agcacataaa tcggaaatgt tactttataa
    16141 tataataccg ctgcaaaaat cattgccacg ataagacgta tcagatttgt tttttcaaat
    16201 ttcagacgaa tcttcatctt cctgctccct gtaattcctg cacacgctgc atccgcccgt
    16261 gcatctcacc tcgattttac ccatttttta cactttacca acgatattct atcatcccat
    16321 aaaaatttgt caattttgtg aagcttaatc ttttcttaag acctcttttt tctcaaaaaa
    16381 ataccccaca atgactttta tggaaaaatc attatgaggt atcaaccctt gcatctatgc
    16441 agactgcgtc atcagagatt ttccattgcc cgccgttccc tgatctttcg tgtgatcacc
    16501 acagccacac cgatcagaaa tggaaaaaca aaagtagcaa aacgatataa cagagacgcc
    16561 gaaccggcta tgcccgtccc gacaatccct gcaaaaagtc cggtaaatac aaactcggtg
    16621 gaaccaatcc ccgccggtgc cggaattacg gcagcaagca taacagacaa tgcggtgatc
    16681 gccatggttt ccaccatatt aatattttta tctcctgcaa aaagaaggta tggcattcca
    16741 taccagaaac agagttttaa caggtttaga ccgaccacac ctgcgaccat tttcttctta
    16801 tgcagaagat atttagaagc ggtttccaga tctgcgcact gttctctcaa ctggtgttcc
    16861 aatgcgtcat actttccctt tttattaaag aaatcaagca ttgcaaaaat cagctgatgg
    16921 aactttgtgg aacagcagaa caggatcagt gccagtgtga tcaccatggt gatagcatac
    16981 cccgccagaa gcagccaggt ataacctcca aaatgtccgc acatataatt ccagcttagg
    17041 aaaaagaaaa tcgccgaata aatcgctatg ctgatcttat ggaatgcata ctggagcatg
    17101 tacattccaa atcccttcga ataatcaact ccgtgttcat tcagataaat gatcgctgca
    17161 acaccggagc cgcttccaag tgtcgcaaca cgataaaagg aacagaaaaa catattttct
    17221 attccccatt gataacgaaa atcagggtta tactgttttg ccagcactgt agtgatcagt
    17281 gcctcaacaa gacaatatat ccctgacatc acgcatatac ctgcgagaac agacggtgtc
    17341 gtttctttta actgctctaa gattggtccc gctgtatccc ggaaggtata tacgatcgct
    17401 cctataatta aaattacaaa tagccatttc aaaagatttt tctgcttttt actaattggt
    17461 ctcgcctctt atttcttctt gaaatttgtg tatcctttct gatgataagg atgctcctcc
    17521 cacagtttat ccgcagtctt cttccactca catgcatatg cttcgcattt tccgcataaa
    17581 tgttctaccg gctcagcctc ttccacatcg gtagaatgtg ctccggtctc atgtaccatt
    17641 ttctgtaaca attccggatt ctcaagcatt ggacatggtc ttaacatatt gtcattgaat
    17701 ggctgaccat ccctgtatgc catgaataat ggctgtttca gacattcaag caatgatttc
    17761 tcacggatat tggcaccgga gtagtggata aatacgcaag gctcaacatc tccctttgga
    17821 ttgatgtggc agtagtttct gccgcctgcg atacatccgc cgacaaactc accatcattc
    17881 tggaagtcca taacgaagat ttcttttccg ccttcttttg cacggacctc acggattctg
    17941 tggtaaatat attcacgctg ttctgctgta ggcatcagtt ccggagctgc cttcatacca
    18001 accggcatca aatggaaata ccatgcaaaa cggctgccat gctcgatcag cagatcgaag
    18061 aattcgtcgg aagtaactgc gtccatgttt ttacgagtat agcatacgct gttaccaaaa
    18121 atcaatccat tttcatggag cagatccatt gcatgaagca ctttatcgta tacaccggct
    18181 cctctacgga aatcgttcgc atcttcgaat ccttccagag aaatagataa ggaaaggttt
    18241 ccgacacgct tcatctcgtc acagaaggcc tgatctacca gcgttccgtt tgtatagcag
    18301 tggaatgcac attcattgtg cttctcacat aacctgataa tatctgcctt acgtaccagt
    18361 ggttcgccac ctgtcatcat atagaagtaa ataccaagtt cttttccctg tgtgacaatg
    18421 ctgtccatct catcaaatgt caggtttaac ttattaccat actctgctgc ccagcatccg
    18481 gtgcaatgca gattacatgc agaagtagga tccattaaga tcagccacgg aatgttacag
    18541 ttgtgcactt ccctcatctt acggattgtc tttgttccta aaaatgcagc ctgaaaacca
    18601 aggtttaatg ctgtcatttt agcaacgtgt ggatctgttt cgtctaaaag acggtttaca
    18661 tatctcatcc atttatgatc tggatttttg atcattgctc tcgcgccatc atacgcttct
    18721 ttgctgaagt tgtttcccat aaatttctct gtaaggtcaa caatctgcag aagtgctttc
    18781 tcacgatcct tattcagatt ttttaatgtt gcatcgactg cgacaccaaa tgcttttctt
    18841 tccattgtct ctactaaatt tgccat
//
