LOCUS       c00012_NZ_FOZH..       21755 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FOZH01000012.1 Enterocloster citroniae strain NLAE-zl-G70, whole
            genome shotgun sequence.
ACCESSION   NZ_FOZH01000012
VERSION     NZ_FOZH01000012
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:51:31
            Original ID  :: NZ_FOZH01000012.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 69995
            Orig. end    :: 91750
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21755
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[79995:81750]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11755
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21755
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21755
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             1223..3583
                     /locus_tag="ctg12_67"
                     /transl_table=11
                     /translation="MNRDFENEFGQEDERLRSRSRRRDSGAGSGADSDTASARRPRSGP
                     DDAGMDRPAAKPRRPVSGTSRVRPEQAETEGRRIAGARPEGNVRSRAAGARPVSGNGLE
                     SRPGTARSRRPEGAGMPGSGTRSSGATAPGSGGRPAGSRAGAETGTRPAGARAGAETGT
                     RPAGARAGAETGARPAGTRAGAETGTRPTGARAGAETGARPAGTRRESRIYTPEVNLAD
                     DRASGARGASLRRNGKDISDRSAAKETAATDKAAGETKKFYRIMLITMIVLEFLIILPG
                     IFVTRQFLKKYNMLQRDPKFNIEQETNPNLNVDKVANMKGYWTVALFGVDSRNNSVGKG
                     NNADVIIIANVNQETSEIKLVSIFRDSYLNLDDEGSYNKINQAYFRGGPEQAIKALNKN
                     LDIQIDDYATFNWKAVADAINILGGVDVELSKAEFYYINAYITETVEATGVASQHLKSA
                     GVNHLDGVQAVAYARLRKMDTDFARTERQREIIQKCFDKLKTADFAVINNVMEVVFKQI
                     LTSVTLDDIIPAAKSLTKYTIADTVGFPMQRSDANMGKKGDCVIPQTLESNVIALHQFL
                     FDDDDYQPSDMVKKISSKISADSGMYNEGKYIDKVGTDGGYIPKPTQSTTQAAETTTKS
                     EEEGTDVSTSEIDEGIIDGENEWDLETDEFGDIIDPPEDESPGSHPGTTRPSGTTRPSG
                     SSSATIPYPGYTTSPADESSSSGVYPGSTTSPGSEVTGPGSTTAAYPGSTTGTSASYPG
                     STTGTSAAYPGSTTTTEGYVPEGPGSVIIGPGN"
     aSDomain        2246..2716
                     /aSDomain="TIGR00350"
                     /aSTool="tigrfam"
                     /description="lytR_cpsA_psr: cell envelope-related function
                     transcriptional attenuator common domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_67_0001"
                     /evalue="3.30E-26"
                     /identifier="TIGR00350"
                     /label="ctg12_67"
                     /locus_tag="ctg12_67"
                     /protein_end="498"
                     /protein_start="341"
                     /score="90.3"
                     /tool="antismash"
                     /translation="NADVIIIANVNQETSEIKLVSIFRDSYLNLDDEGSYNKINQAYFR
                     GGPEQAIKALNKNLDIQIDDYATFNWKAVADAINILGGVDVELSKAEFYYINAYITETV
                     EATGVASQHLKSAGVNHLDGVQAVAYARLRKMDTDFARTERQREIIQKCFDKL"
     PFAM_domain     2246..2719
                     /aSDomain="LytR_cpsA_psr"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03816.16"
                     /description="LytR_cpsA_psr family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_67_0001"
                     /evalue="1.60E-33"
                     /label="ctg12_67"
                     /locus_tag="ctg12_67"
                     /protein_end="499"
                     /protein_start="341"
                     /score="116.1"
                     /tool="antismash"
                     /translation="NADVIIIANVNQETSEIKLVSIFRDSYLNLDDEGSYNKINQAYFR
                     GGPEQAIKALNKNLDIQIDDYATFNWKAVADAINILGGVDVELSKAEFYYINAYITETV
                     EATGVASQHLKSAGVNHLDGVQAVAYARLRKMDTDFARTERQREIIQKCFDKLK"
     CDS             3644..3781
                     /locus_tag="ctg12_68"
                     /transl_table=11
                     /translation="MTVPAGPFLVLYKKMVTYLSQIIDTLYSESEDMRANQERGYMNVR
                     "
     CDS             3781..4017
                     /locus_tag="ctg12_69"
                     /transl_table=11
                     /translation="MIRNTVGNHTIIRDMKAVHIMNRSLTRDPILIRGRQGARDHWEAK
                     DHWEAKDHWEAGDHWETRDRPETGVLQRKGADC"
     CDS             4077..5303
                     /locus_tag="ctg12_70"
                     /transl_table=11
                     /translation="MVGVHVAASRYLNIYASADPSGKENGDQPVPGPDNGQMDGKGQNG
                     QSGQGGSGSHEKVPNSGGGGVADVSDIVEAAMPTVVAITSTTVYQSNNYGYGWFFGGPQ
                     TYEVPSSGSGIIIGENDQELLIVTNNHVVESASSMKVAFIDNEVVDAVIKGTDAETDLA
                     VISVPLDQIKADTKSKISVAKLGSSDDLKVGQGVIAIGNALGYGQSVTVGYVSALDREV
                     RVSNNATRTLLQTDAAINPGNSGGALLNMKGEVVGINAAKYSSTEVEGIGYAIPISKAQ
                     DIMSQLMNRKTMNPVEEAKRGYLGIQGTTVDEETASLFGMPRGVYVYKVLGDGAAAESD
                     LRDKDIITKVDGQSVKTMTELQELLACYELGEELELTVQTQENGQYQERIVQVTLKSMP
                     QEEQSNPAQ"
     PFAM_domain     4410..4850
                     /aSDomain="Trypsin_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13365.8"
                     /description="Trypsin-like peptidase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_70_0002"
                     /evalue="9.50E-28"
                     /label="ctg12_70"
                     /locus_tag="ctg12_70"
                     /protein_end="258"
                     /protein_start="111"
                     /score="98.1"
                     /tool="antismash"
                     /translation="GSGIIIGENDQELLIVTNNHVVESASSMKVAFIDNEVVDAVIKGT
                     DAETDLAVISVPLDQIKADTKSKISVAKLGSSDDLKVGQGVIAIGNALGYGQSVTVGYV
                     SALDREVRVSNNATRTLLQTDAAINPGNSGGALLNMKGEVVGI"
     PFAM_domain     4980..5213
                     /aSDomain="PDZ_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13180.8"
                     /description="PDZ domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_70_0003"
                     /evalue="2.60E-11"
                     /label="ctg12_70"
                     /locus_tag="ctg12_70"
                     /protein_end="379"
                     /protein_start="301"
                     /score="43.8"
                     /tool="antismash"
                     /translation="GYLGIQGTTVDEETASLFGMPRGVYVYKVLGDGAAAESDLRDKDI
                     ITKVDGQSVKTMTELQELLACYELGEELELTVQ"
     CDS             5422..6879
                     /locus_tag="ctg12_71"
                     /transl_table=11
                     /translation="MLVTERRTDLDDKDYTEDVKPSGQDKEDNKEDDKYEKVCYMCRRP
                     ESKAGSMISMPGGMNLCHDCMQKAFDSVTKGGMDFSKFSNMPYMNMNLNDLNVTPPAVE
                     IPKKQKIKKKSQEQPVLTMKDIPTPHVIKGKLDEYVIGQEKAKKVVSVAVYNHYKRAFL
                     DGKAGQGEGNAENAEPDDVVIEKSNILMIGPTGSGKTYLVKTLARLLDVPLAIADATSL
                     TEAGYIGDDIESVVSKLLAAADNDVERAQRGIIFIDEIDKIAKKKQTNTRDVSGESVQQ
                     ELLKLLEGSTVEVPVGSNQKNAMTPMATVNTDNILFICGGAFPDLEEIIKERLKKKSSM
                     GFGSVLKDTYDSDPNILSHVTNEDLRTFGMIPEFLGRLPVTVTLQGLTEDMMVRILKEP
                     RNAITKQYEKLLSMDEVRLVFEDDALMWIAEEALKRGTGARALRAILEEFMLDIMYEIP
                     KDPNIGSVVVTRPYLEKNGGPLIQMRG"
     aSDomain        5524..6858
                     /aSDomain="TIGR00382"
                     /aSTool="tigrfam"
                     /description="clpX: ATP-dependent Clp protease, ATP-binding
                     subunit ClpX"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_71_0002"
                     /evalue="1.80E-144"
                     /identifier="TIGR00382"
                     /label="ctg12_71"
                     /locus_tag="ctg12_71"
                     /protein_end="479"
                     /protein_start="34"
                     /score="479.7"
                     /tool="antismash"
                     /translation="YEKVCYMCRRPESKAGSMISMPGGMNLCHDCMQKAFDSVTKGGMD
                     FSKFSNMPYMNMNLNDLNVTPPAVEIPKKQKIKKKSQEQPVLTMKDIPTPHVIKGKLDE
                     YVIGQEKAKKVVSVAVYNHYKRAFLDGKAGQGEGNAENAEPDDVVIEKSNILMIGPTGS
                     GKTYLVKTLARLLDVPLAIADATSLTEAGYIGDDIESVVSKLLAAADNDVERAQRGIIF
                     IDEIDKIAKKKQTNTRDVSGESVQQELLKLLEGSTVEVPVGSNQKNAMTPMATVNTDNI
                     LFICGGAFPDLEEIIKERLKKKSSMGFGSVLKDTYDSDPNILSHVTNEDLRTFGMIPEF
                     LGRLPVTVTLQGLTEDMMVRILKEPRNAITKQYEKLLSMDEVRLVFEDDALMWIAEEAL
                     KRGTGARALRAILEEFMLDIMYEIPKDPNIGSVVVTRPYLEKNGGP"
     PFAM_domain     5533..5634
                     /aSDomain="zf-C4_ClpX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06689.15"
                     /description="ClpX C4-type zinc finger"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_71_0004"
                     /evalue="1.20E-05"
                     /label="ctg12_71"
                     /locus_tag="ctg12_71"
                     /protein_end="71"
                     /protein_start="37"
                     /score="25.2"
                     /tool="antismash"
                     /translation="VCYMCRRPESKAGSMISMPGGMNLCHDCMQKAFD"
     PFAM_domain     5974..6561
                     /aSDomain="AAA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07724.16"
                     /description="AAA domain (Cdc48 subfamily)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_71_0005"
                     /evalue="1.10E-45"
                     /label="ctg12_71"
                     /locus_tag="ctg12_71"
                     /protein_end="380"
                     /protein_start="184"
                     /score="155.9"
                     /tool="antismash"
                     /translation="EKSNILMIGPTGSGKTYLVKTLARLLDVPLAIADATSLTEAGYIG
                     DDIESVVSKLLAAADNDVERAQRGIIFIDEIDKIAKKKQTNTRDVSGESVQQELLKLLE
                     GSTVEVPVGSNQKNAMTPMATVNTDNILFICGGAFPDLEEIIKERLKKKSSMGFGSVLK
                     DTYDSDPNILSHVTNEDLRTFGMIPEFLGRLPV"
     PFAM_domain     6580..6795
                     /aSDomain="ClpB_D2-small"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10431.11"
                     /description="C-terminal, D2-small domain, of ClpB protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_71_0006"
                     /evalue="7.10E-14"
                     /label="ctg12_71"
                     /locus_tag="ctg12_71"
                     /protein_end="458"
                     /protein_start="386"
                     /score="51.7"
                     /tool="antismash"
                     /translation="LTEDMMVRILKEPRNAITKQYEKLLSMDEVRLVFEDDALMWIAEE
                     ALKRGTGARALRAILEEFMLDIMYEIP"
     CDS             complement(6951..8702)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 103.6; E-value: 2.4e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_72"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.6e-17, bitscore:
                     55.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADCPFNSASETIADFIYRYGSQQQIIGNPEDIPCMDFVSTDFSI
                     IYTPLDTVEPISLRRTSYYSIPGLYTLLDSSSMEASGILSTHSSPALGNRGRGVLIGII
                     DTGIDYTNPLFRNPDGTTRINSIWDQSLPEDKTLIPPGVPNRYNASGATYGTEYTREQI
                     NQALESDDPLALVPSTDTNGHGTFLAGIAAGGFLPEEDFTGAAPECELLIVKLKPAKQY
                     LRDFYLVSSDADAYQENDIMMGIKYLRVEAFSRGKPLVILLGIGSNLGSHEGTSPLSVM
                     LQDISRYLGTATVIAAGNETGRGHHYMGTIPTGESSVDVEIRVGQPESQRGFVVELWAS
                     TIDTYSVGFLSPSGETISRIPIIAGNETSIPFLLEPTVITVNYQLIEAGSGRQLIFMRF
                     EAPTTGIWKIRVYNTQFLTGQFNMWLPTHNLISEETVFLTPSPYTTITLPGNAPSPITV
                     GAYNHLNNSIYIHSSRGYTVGGLIKPDLAAPGVDVSGPAIGRRIGTSVPMTTRTGTSVA
                     AAHVAGAAANLLGWGIVEGNNITMSEASIKAYLIRGARRNPALSYPNREWGYGALDLYE
                     TFLRLRE"
     PFAM_domain     complement(6993..7370)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_72_0008"
                     /evalue="5.30E-14"
                     /label="ctg12_72"
                     /locus_tag="ctg12_72"
                     /protein_end="570"
                     /protein_start="444"
                     /score="52.2"
                     /tool="antismash"
                     /translation="TITLPGNAPSPITVGAYNHLNNSIYIHSSRGYTVGGLIKPDLAAP
                     GVDVSGPAIGRRIGTSVPMTTRTGTSVAAAHVAGAAANLLGWGIVEGNNITMSEASIKA
                     YLIRGARRNPALSYPNREWGYG"
     PFAM_domain     complement(7782..8417)
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_72_0007"
                     /evalue="1.90E-13"
                     /label="ctg12_72"
                     /locus_tag="ctg12_72"
                     /protein_end="307"
                     /protein_start="95"
                     /score="50.4"
                     /tool="antismash"
                     /translation="GRGVLIGIIDTGIDYTNPLFRNPDGTTRINSIWDQSLPEDKTLIP
                     PGVPNRYNASGATYGTEYTREQINQALESDDPLALVPSTDTNGHGTFLAGIAAGGFLPE
                     EDFTGAAPECELLIVKLKPAKQYLRDFYLVSSDADAYQENDIMMGIKYLRVEAFSRGKP
                     LVILLGIGSNLGSHEGTSPLSVMLQDISRYLGTATVIAAGNETGRGHHY"
     CDS             8822..9301
                     /locus_tag="ctg12_73"
                     /transl_table=11
                     /translation="MIYGWIIGGLAALDLGIKSVIESEEDDTFPRDLPSAKGLIKVHKN
                     HNAGFPFGFMKERPELVKGIPLMVISAMAGALCALLQDKGKTAQKAGIAIIIGGAISNL
                     YDRVVRGYVVDYFSIEWEPIKKVVFNLGDMFVFLGSTIIMLEQTAKSLAEVRKKK"
     PFAM_domain     8846..9259
                     /aSDomain="Peptidase_A8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01252.20"
                     /description="Signal peptidase (SPase) II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_73_0009"
                     /evalue="1.40E-23"
                     /label="ctg12_73"
                     /locus_tag="ctg12_73"
                     /protein_end="146"
                     /protein_start="8"
                     /score="83.9"
                     /tool="antismash"
                     /translation="GLAALDLGIKSVIESEEDDTFPRDLPSAKGLIKVHKNHNAGFPFG
                     FMKERPELVKGIPLMVISAMAGALCALLQDKGKTAQKAGIAIIIGGAISNLYDRVVRGY
                     VVDYFSIEWEPIKKVVFNLGDMFVFLGSTIIMLE"
     CDS             complement(9489..9848)
                     /locus_tag="ctg12_74"
                     /transl_table=11
                     /translation="MENGIVKPMVRSLLISYVLSGILLAALAFALYKLHLKEGQVNLMV
                     YAVYFITCLAGGFVAGKGIRQRRFFWGLLAGLFYFVVLFAVSWAMNMGSPIDMERSVTV
                     MGVCALGGTIGGMIS"
     aSDomain        complement(9492..9827)
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_74_0003"
                     /evalue="1.20E-28"
                     /identifier="TIGR04086"
                     /label="ctg12_74"
                     /locus_tag="ctg12_74"
                     /protein_end="119"
                     /protein_start="7"
                     /score="97.6"
                     /tool="antismash"
                     /translation="PMVRSLLISYVLSGILLAALAFALYKLHLKEGQVNLMVYAVYFIT
                     CLAGGFVAGKGIRQRRFFWGLLAGLFYFVVLFAVSWAMNMGSPIDMERSVTVMGVCALG
                     GTIGGMIS"
     PFAM_domain     complement(9492..9830)
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_74_0010"
                     /evalue="4.00E-30"
                     /label="ctg12_74"
                     /locus_tag="ctg12_74"
                     /protein_end="119"
                     /protein_start="6"
                     /score="104.4"
                     /tool="antismash"
                     /translation="KPMVRSLLISYVLSGILLAALAFALYKLHLKEGQVNLMVYAVYFI
                     TCLAGGFVAGKGIRQRRFFWGLLAGLFYFVVLFAVSWAMNMGSPIDMERSVTVMGVCAL
                     GGTIGGMIS"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_75"
                     /sec_met_domain="TIGR03973 (E-value: 2.5e-27, bitscore:
                     87.8, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.4e-27, bitscore: 88.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHVKTLNTNTLKDTMKKGGCGECQTSCQSACKTSCTVGNQSCEN
                     ANR"
     aSDomain        10004..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_75_0004"
                     /evalue="7.40E-26"
                     /identifier="TIGR03973"
                     /label="ctg12_75"
                     /locus_tag="ctg12_75"
                     /protein_end="44"
                     /protein_start="1"
                     /score="87.8"
                     /tool="antismash"
                     /translation="KHVKTLNTNTLKDTMKKGGCGECQTSCQSACKTSCTVGNQSCE"
     PFAM_domain     10004..10135
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_75_0011"
                     /evalue="1.60E-25"
                     /label="ctg12_75"
                     /locus_tag="ctg12_75"
                     /protein_end="45"
                     /protein_start="1"
                     /score="88.8"
                     /tool="antismash"
                     /translation="KHVKTLNTNTLKDTMKKGGCGECQTSCQSACKTSCTVGNQSCEN"
     CDS             10352..11755
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_76"
                     /sec_met_domain="PF04055 (E-value: 5.9e-13, bitscore: 42.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.6e-15, bitscore: 48.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-19, bitscore:
                     62.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.2e-29,
                     bitscore: 95.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIHQFINNGYHIILDVNSGSVHVVDPVVYDAVAVVSELVPEMEKP
                     EPLSSKVKSDVFDRLWGKYTPEELGEALEDIEELIAMEQLLTKDIYRDFVVDFKQRKTV
                     VKALCLHIAHDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGNREHLEVDF
                     FGGEPLMNWDVVKRLVEYGRSQEAEHHKKFRFTITTNGVLLNDEIMDFCNREMSNVVMS
                     LDGRKDINDKMRPFRNGSGSYDLTVPKFQKFAKSRGQKDYYVRGTFTRNNLDFAEDVLH
                     YADLGFEQMSMEPVVSDPAEDYSIRREDLPAILKEYDKLALEYIKRKKEGRGFNFFHFM
                     LDLKAGPCVAKRMAGCGSGTEYLAVTPWGDFYPCHQFVGNEEFLMGNVDTGIVNTDIRD
                     EFKTCNVYAKEGCKDCFARFYCSGGCSANAYNSSGSINGAYEIGCEMQKKRIECAIMIK
                     AALADEEAE"
     aSDomain        10355..11731
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_76_0005"
                     /evalue="4.90E-237"
                     /identifier="TIGR03974"
                     /label="ctg12_76"
                     /locus_tag="ctg12_76"
                     /protein_end="460"
                     /protein_start="1"
                     /score="785.0"
                     /tool="antismash"
                     /translation="IHQFINNGYHIILDVNSGSVHVVDPVVYDAVAVVSELVPEMEKPE
                     PLSSKVKSDVFDRLWGKYTPEELGEALEDIEELIAMEQLLTKDIYRDFVVDFKQRKTVV
                     KALCLHIAHDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGNREHLEVDFF
                     GGEPLMNWDVVKRLVEYGRSQEAEHHKKFRFTITTNGVLLNDEIMDFCNREMSNVVMSL
                     DGRKDINDKMRPFRNGSGSYDLTVPKFQKFAKSRGQKDYYVRGTFTRNNLDFAEDVLHY
                     ADLGFEQMSMEPVVSDPAEDYSIRREDLPAILKEYDKLALEYIKRKKEGRGFNFFHFML
                     DLKAGPCVAKRMAGCGSGTEYLAVTPWGDFYPCHQFVGNEEFLMGNVDTGIVNTDIRDE
                     FKTCNVYAKEGCKDCFARFYCSGGCSANAYNSSGSINGAYEIGCEMQKKRIECAIMIKA
                     A"
     PFAM_domain     10676..11077
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_76_0012"
                     /evalue="9.60E-14"
                     /label="ctg12_76"
                     /locus_tag="ctg12_76"
                     /protein_end="242"
                     /protein_start="108"
                     /score="52.1"
                     /tool="antismash"
                     /translation="CLHIAHDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANS
                     GNREHLEVDFFGGEPLMNWDVVKRLVEYGRSQEAEHHKKFRFTITTNGVLLNDEIMDFC
                     NREMSNVVMSLDGRKDINDKMRPFRNGSGS"
     aSDomain        11417..11668
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_76_0006"
                     /evalue="6.90E-18"
                     /identifier="TIGR04085"
                     /label="ctg12_76"
                     /locus_tag="ctg12_76"
                     /protein_end="439"
                     /protein_start="355"
                     /score="62.9"
                     /tool="antismash"
                     /translation="CGSGTEYLAVTPWGDFYPCHQFVGNEEFLMGNVDTGIVNTDIRDE
                     FKTCNVYAKEGCKDCFARFYCSGGCSANAYNSSGSINGA"
     CDS             11757..12902
                     /locus_tag="ctg12_77"
                     /transl_table=11
                     /translation="MKYQVITKDQKAKRARMETVHGVIETPVFMNVGTVGAIKGAVSTD
                     DLREIGTQVELSNTYHLHVRTGDKLIKEFGGLHKFMSWDRPILTDSGGFQVFSLTKLRK
                     IKEEGVYFNSHIDGHKIFMGPEESMQIQSNLGSTIAMAFDECPPSHASDEYIRQSVDRT
                     TRWLARCKEEMARLNGLPDTVNREQLLFGINQGGVVDEIRIQHAKTIREMDLDGYAVGG
                     LAVGESHEEMYHILDVTVPHLPEDKPVYLMGVGTPANILEAVDRGVDFFDCVYPSRNGR
                     HGHVYTNHGKLNLFNQKYELDSRPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCTL
                     HNLYFYNTMMKEIRNAIEEHRYSEYKAAKLAGMESSLKANE"
     aSDomain        11763..12875
                     /aSDomain="TIGR00430"
                     /aSTool="tigrfam"
                     /description="Q_tRNA_tgt: tRNA-guanine transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_77_0007"
                     /evalue="3.70E-146"
                     /identifier="TIGR00430"
                     /label="ctg12_77"
                     /locus_tag="ctg12_77"
                     /protein_end="373"
                     /protein_start="2"
                     /score="484.8"
                     /tool="antismash"
                     /translation="YQVITKDQKAKRARMETVHGVIETPVFMNVGTVGAIKGAVSTDDL
                     REIGTQVELSNTYHLHVRTGDKLIKEFGGLHKFMSWDRPILTDSGGFQVFSLTKLRKIK
                     EEGVYFNSHIDGHKIFMGPEESMQIQSNLGSTIAMAFDECPPSHASDEYIRQSVDRTTR
                     WLARCKEEMARLNGLPDTVNREQLLFGINQGGVVDEIRIQHAKTIREMDLDGYAVGGLA
                     VGESHEEMYHILDVTVPHLPEDKPVYLMGVGTPANILEAVDRGVDFFDCVYPSRNGRHG
                     HVYTNHGKLNLFNQKYELDSRPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCTLHN
                     LYFYNTMMKEIRNAIEEHRYSEYKAAKLAGM"
     aSDomain        11763..12878
                     /aSDomain="TIGR00449"
                     /aSTool="tigrfam"
                     /description="tgt_general: tRNA-guanine family
                     transglycosylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_77_0008"
                     /evalue="1.20E-139"
                     /identifier="TIGR00449"
                     /label="ctg12_77"
                     /locus_tag="ctg12_77"
                     /protein_end="374"
                     /protein_start="2"
                     /score="463.2"
                     /tool="antismash"
                     /translation="YQVITKDQKAKRARMETVHGVIETPVFMNVGTVGAIKGAVSTDDL
                     REIGTQVELSNTYHLHVRTGDKLIKEFGGLHKFMSWDRPILTDSGGFQVFSLTKLRKIK
                     EEGVYFNSHIDGHKIFMGPEESMQIQSNLGSTIAMAFDECPPSHASDEYIRQSVDRTTR
                     WLARCKEEMARLNGLPDTVNREQLLFGINQGGVVDEIRIQHAKTIREMDLDGYAVGGLA
                     VGESHEEMYHILDVTVPHLPEDKPVYLMGVGTPANILEAVDRGVDFFDCVYPSRNGRHG
                     HVYTNHGKLNLFNQKYELDSRPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCTLHN
                     LYFYNTMMKEIRNAIEEHRYSEYKAAKLAGME"
     PFAM_domain     11787..12866
                     /aSDomain="TGT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01702.20"
                     /description="Queuine tRNA-ribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_77_0013"
                     /evalue="5.80E-144"
                     /label="ctg12_77"
                     /locus_tag="ctg12_77"
                     /protein_end="370"
                     /protein_start="10"
                     /score="479.7"
                     /tool="antismash"
                     /translation="KAKRARMETVHGVIETPVFMNVGTVGAIKGAVSTDDLREIGTQVE
                     LSNTYHLHVRTGDKLIKEFGGLHKFMSWDRPILTDSGGFQVFSLTKLRKIKEEGVYFNS
                     HIDGHKIFMGPEESMQIQSNLGSTIAMAFDECPPSHASDEYIRQSVDRTTRWLARCKEE
                     MARLNGLPDTVNREQLLFGINQGGVVDEIRIQHAKTIREMDLDGYAVGGLAVGESHEEM
                     YHILDVTVPHLPEDKPVYLMGVGTPANILEAVDRGVDFFDCVYPSRNGRHGHVYTNHGK
                     LNLFNQKYELDSRPIEEGCGCPACRSYSRAYIRHLLKAKEMLGMRLCTLHNLYFYNTMM
                     KEIRNAIEEHRYSEYKAAKL"
     CDS             12950..13231
                     /locus_tag="ctg12_78"
                     /transl_table=11
                     /translation="MNTSSPIFWILYIVLLGGMLYFMAIRPQKKEKQRQQELLNSVAVG
                     DTILTSSGFYGVIIDMTDDTVIVEFGNNKNCRIPMQKAAIAQVEKAEA"
     aSDomain        12968..13213
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_78_0009"
                     /evalue="1.10E-21"
                     /identifier="TIGR00739"
                     /label="ctg12_78"
                     /locus_tag="ctg12_78"
                     /protein_end="88"
                     /protein_start="6"
                     /score="74.6"
                     /tool="antismash"
                     /translation="IFWILYIVLLGGMLYFMAIRPQKKEKQRQQELLNSVAVGDTILTS
                     SGFYGVIIDMTDDTVIVEFGNNKNCRIPMQKAAIAQV"
     PFAM_domain     12977..13210
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_78_0014"
                     /evalue="3.70E-26"
                     /label="ctg12_78"
                     /locus_tag="ctg12_78"
                     /protein_end="87"
                     /protein_start="9"
                     /score="90.9"
                     /tool="antismash"
                     /translation="ILYIVLLGGMLYFMAIRPQKKEKQRQQELLNSVAVGDTILTSSGF
                     YGVIIDMTDDTVIVEFGNNKNCRIPMQKAAIAQ"
     CDS             13358..13996
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 58; E-value: 1.8e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_79"
                     /transl_table=11
                     /translation="MIKHIVFDMGQVLVSYVGDLVCQKYIEDEQERKEVSTSVFVSPEW
                     ILLDMGVMPEEEALKKMQDRLDTEHKRDMAAWCFWHWHEYNMRPKEGMEEVVRWLKSMG
                     YGIYLCSNASVRLLTCYKEVIPAIDCFDGVLFSADVQCLKPQKEMYQHLFDRFRLKPEE
                     CFFIDDLSLNIEGARRCGMDGYCFEDGDVGKLKEVLGSLNRQQPHFNEK"
     PFAM_domain     13517..13906
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_79_0015"
                     /evalue="2.80E-15"
                     /label="ctg12_79"
                     /locus_tag="ctg12_79"
                     /protein_end="183"
                     /protein_start="53"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PEEEALKKMQDRLDTEHKRDMAAWCFWHWHEYNMRPKEGMEEVVR
                     WLKSMGYGIYLCSNASVRLLTCYKEVIPAIDCFDGVLFSADVQCLKPQKEMYQHLFDRF
                     RLKPEECFFIDDLSLNIEGARRCGMD"
     aSDomain        13598..13906
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_79_0010"
                     /evalue="1.30E-14"
                     /identifier="TIGR01509"
                     /label="ctg12_79"
                     /locus_tag="ctg12_79"
                     /protein_end="183"
                     /protein_start="80"
                     /score="52.6"
                     /tool="antismash"
                     /translation="HWHEYNMRPKEGMEEVVRWLKSMGYGIYLCSNASVRLLTCYKEVI
                     PAIDCFDGVLFSADVQCLKPQKEMYQHLFDRFRLKPEECFFIDDLSLNIEGARRCGMD"
     CDS             15244..17010
                     /locus_tag="ctg12_80"
                     /transl_table=11
                     /translation="VDLYGDLRKMMDVASGRRKASLVLKGGTVVNVFTEKTEVADIAIE
                     DGYIAGIGDYEGEHNVDLSGRYICPGFIDGHIHIESAMVSPPEFEKAVLPHGTTAVIAD
                     PHEIGNVAGCQGIDYMLETTKDLDLDVFIMMPSCVPATALDESGAVLGPEDLKPYYDNP
                     RVLGLAEVMNSLGVVAGMDDLMGKLSDAGSRGMVIDGHAPFLEGNGLNAYVCAGVLSDH
                     ECSDIDEALKKLGRGQYIMIREGTAARNLEALMPLFAAPYYERCMLVTDDKHPGDLISM
                     GHIDYIIRKAVSLGADPIKAIKMGTLHSARYFGLKDRGAVMPGLRADLAVLEDLKDFRV
                     LAVYKDGKLAAEKGVCIQEKEDKSRELASAFPRVFDSFHLDEITLKDLELEKKGTMQRV
                     IQFKPHELLTQERILPWPDDDTAAAQGHRAQGVDLNEDIVKAAVFERHLHTGHTGIGFI
                     GGYGLKKGAVATSVAHDSHNLIVIGTNDRDMVLAANAVRKNKGGLAVAVDGQVTGELAL
                     PIGGIMTQASVYEVESQLEKLKEQTRKLGISEDIDAFMTLAFVSLPVIPKLRINSYGVI
                     DVDRQEVVEAVF"
     aSDomain        15307..16995
                     /aSDomain="TIGR01178"
                     /aSTool="tigrfam"
                     /description="ade: adenine deaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_80_0011"
                     /evalue="5.30E-181"
                     /identifier="TIGR01178"
                     /label="ctg12_80"
                     /locus_tag="ctg12_80"
                     /protein_end="584"
                     /protein_start="21"
                     /score="600.8"
                     /tool="antismash"
                     /translation="LVLKGGTVVNVFTEKTEVADIAIEDGYIAGIGDYEGEHNVDLSGR
                     YICPGFIDGHIHIESAMVSPPEFEKAVLPHGTTAVIADPHEIGNVAGCQGIDYMLETTK
                     DLDLDVFIMMPSCVPATALDESGAVLGPEDLKPYYDNPRVLGLAEVMNSLGVVAGMDDL
                     MGKLSDAGSRGMVIDGHAPFLEGNGLNAYVCAGVLSDHECSDIDEALKKLGRGQYIMIR
                     EGTAARNLEALMPLFAAPYYERCMLVTDDKHPGDLISMGHIDYIIRKAVSLGADPIKAI
                     KMGTLHSARYFGLKDRGAVMPGLRADLAVLEDLKDFRVLAVYKDGKLAAEKGVCIQEKE
                     DKSRELASAFPRVFDSFHLDEITLKDLELEKKGTMQRVIQFKPHELLTQERILPWPDDD
                     TAAAQGHRAQGVDLNEDIVKAAVFERHLHTGHTGIGFIGGYGLKKGAVATSVAHDSHNL
                     IVIGTNDRDMVLAANAVRKNKGGLAVAVDGQVTGELALPIGGIMTQASVYEVESQLEKL
                     KEQTRKLGISEDIDAFMTLAFVSLPVIPKLRINSYGVIDVDRQEVV"
     PFAM_domain     15442..16290
                     /aSDomain="Amidohydro_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01979.22"
                     /description="Amidohydrolase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_80_0016"
                     /evalue="1.80E-21"
                     /label="ctg12_80"
                     /locus_tag="ctg12_80"
                     /protein_end="349"
                     /protein_start="66"
                     /score="77.0"
                     /tool="antismash"
                     /translation="YICPGFIDGHIHIESAMVSPPEFEKAVLPHGTTAVIADPHEIGNV
                     AGCQGIDYMLETTKDLDLDVFIMMPSCVPATALDESGAVLGPEDLKPYYDNPRVLGLAE
                     VMNSLGVVAGMDDLMGKLSDAGSRGMVIDGHAPFLEGNGLNAYVCAGVLSDHECSDIDE
                     ALKKLGRGQYIMIREGTAARNLEALMPLFAAPYYERCMLVTDDKHPGDLISMGHIDYII
                     RKAVSLGADPIKAIKMGTLHSARYFGLKDRGAVMPGLRADLAVLEDLKDFRVLAVYKDG
                     KL"
     PFAM_domain     16525..16986
                     /aSDomain="Adenine_deam_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13382.8"
                     /description="Adenine deaminase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_80_0017"
                     /evalue="2.80E-57"
                     /label="ctg12_80"
                     /locus_tag="ctg12_80"
                     /protein_end="581"
                     /protein_start="427"
                     /score="192.9"
                     /tool="antismash"
                     /translation="RAQGVDLNEDIVKAAVFERHLHTGHTGIGFIGGYGLKKGAVATSV
                     AHDSHNLIVIGTNDRDMVLAANAVRKNKGGLAVAVDGQVTGELALPIGGIMTQASVYEV
                     ESQLEKLKEQTRKLGISEDIDAFMTLAFVSLPVIPKLRINSYGVIDVDRQ"
     CDS             17138..18031
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 225.5; E-value: 2.6e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_81"
                     /sec_met_domain="Peptidase_S8 (E-value: 6.8e-51, bitscore:
                     166.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNQAREDINCDIVYSMGITGKGVGVAVLDTGVYLHEDFKDRVTAF
                     ADYVNQRPQPYDDNGHGTHISAMIGGSGASSEGKYRGVAPGCSLISVKVLDHKGNGYAS
                     DVLAGLKWIREHMQEYGIRIVNISVGSLSRRDMTENSILVRGVNAAWDDGLVVVVAAGN
                     HGPGRMTITTPGISRKVITVGCSDDHKEVEVMGSRMVDYSGRGPTLACICKPDIVAPGS
                     GIVSCCNEPGRYFSKSGTSMSTPLVSGAIALLLEKYPEMSNKDVKLRIRERAVNLGLPH
                     NQQGWGKLDVARLLED"
     PFAM_domain     17195..17998
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_81_0018"
                     /evalue="1.00E-49"
                     /label="ctg12_81"
                     /locus_tag="ctg12_81"
                     /protein_end="287"
                     /protein_start="19"
                     /score="169.4"
                     /tool="antismash"
                     /translation="GKGVGVAVLDTGVYLHEDFKDRVTAFADYVNQRPQPYDDNGHGTH
                     ISAMIGGSGASSEGKYRGVAPGCSLISVKVLDHKGNGYASDVLAGLKWIREHMQEYGIR
                     IVNISVGSLSRRDMTENSILVRGVNAAWDDGLVVVVAAGNHGPGRMTITTPGISRKVIT
                     VGCSDDHKEVEVMGSRMVDYSGRGPTLACICKPDIVAPGSGIVSCCNEPGRYFSKSGTS
                     MSTPLVSGAIALLLEKYPEMSNKDVKLRIRERAVNLGLPHNQQGWG"
     CDS             complement(18146..19006)
                     /locus_tag="ctg12_82"
                     /transl_table=11
                     /translation="MWLADKWNDYEVIDCSNGEKLERWGNYLLVRPDPQVIWDTVKTHK
                     GWKHMNGHYHRSSKGGGEWEFFDLPEQWSIGYNGLTFNLKPFSFKHTGLFPEQAANWDW
                     FGDKIKQAGRPIKVLNLFAYTGGATLAAAKAGASVTHVDASKGMVAWAKENAASSGLAD
                     APVRWIVDDCVKFVEREIRRGNRYDAVIMDPPSYGRGPKGEIWKIEDAIHPLVKLCVQL
                     LSDKPLFFLINSYTTGLAPSVLSYMLGVEVIPRFGGTVNAQEVGLPVTQSGLVLPCGAS
                     GRWEA"
     PFAM_domain     complement(18407..18844)
                     /aSDomain="Methyltrans_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10672.11"
                     /description="S-adenosylmethionine-dependent
                     methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_82_0019"
                     /evalue="2.30E-15"
                     /label="ctg12_82"
                     /locus_tag="ctg12_82"
                     /protein_end="200"
                     /protein_start="54"
                     /score="56.6"
                     /tool="antismash"
                     /translation="HRSSKGGGEWEFFDLPEQWSIGYNGLTFNLKPFSFKHTGLFPEQA
                     ANWDWFGDKIKQAGRPIKVLNLFAYTGGATLAAAKAGASVTHVDASKGMVAWAKENAAS
                     SGLADAPVRWIVDDCVKFVEREIRRGNRYDAVIMDPPSYGRG"
     CDS             19306..20664
                     /locus_tag="ctg12_83"
                     /transl_table=11
                     /translation="MKKHTVAVWVLAAVLSLGTATISAMAAEGWAQSGSSWVYYDSNGN
                     RVYNAWKKGADNQWRYLDGEGNMATSAWVDSDYYVDSNGIILTDKWLKLTNDDGEYEWY
                     YFGSSGKMMSDAWKKIDNKWYHFDGDGRMELGWILDDMYYTGTDGVMRTGWQKLEPPDE
                     DDDNRDRVTPGIDSVTDDDGRYWYYFSSSGKKFAPDSSDGDYTARKIDGTYYCFDETGA
                     MQTGWKNVRSSSNDSIEDYMYFGADGKARIGWYSIEPPDDLEGYDGDVEWFYFTNSGKP
                     RAADTERLTTNDIVKLNGKSYLFNHLGNPVYGLKKVYTGSGDDDWTTFYFGDKNKSCVQ
                     KGKIKVTEDDGNKSDFYFADNGRGYNGVKDNYLYYKGKLQKATDGQKYVCYRVDNKNYV
                     VNSSGKVMKSTKVKNSDGVKFVTNASGQLTSADEDTDIDSYVTEPMEPYCTED"
     PFAM_domain     19387..19524
                     /aSDomain="Choline_bind_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19127.2"
                     /description="Choline-binding repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_83_0020"
                     /evalue="6.40E-09"
                     /label="ctg12_83"
                     /locus_tag="ctg12_83"
                     /protein_end="73"
                     /protein_start="27"
                     /score="35.8"
                     /tool="antismash"
                     /translation="EGWAQSGSSWVYYDSNGNRVYNAWKKGADNQWRYLDGEGNMATSA
                     W"
     PFAM_domain     19651..19704
                     /aSDomain="Choline_bind_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01473.22"
                     /description="Putative cell wall binding repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_83_0021"
                     /evalue="1.30E-05"
                     /label="ctg12_83"
                     /locus_tag="ctg12_83"
                     /protein_end="133"
                     /protein_start="115"
                     /score="25.3"
                     /tool="antismash"
                     /translation="AWKKIDNKWYHFDGDGRM"
     CDS             21055..21372
                     /locus_tag="ctg12_84"
                     /transl_table=11
                     /translation="MASQVMRITLKAYDHQLVDQSAGKIIETVKKTGSQVSGPVPLPTK
                     KEVVTILRAVHKYKDSREQFEQRTHKRLIDITAPSQKTVDALSRLEMPAGVYIDIKMKT
                     K"
     aSDomain        21067..21360
                     /aSDomain="TIGR01049"
                     /aSTool="tigrfam"
                     /description="rpsJ_bact: ribosomal protein uS10"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg12_84_0012"
                     /evalue="8.80E-41"
                     /identifier="TIGR01049"
                     /label="ctg12_84"
                     /locus_tag="ctg12_84"
                     /protein_end="102"
                     /protein_start="4"
                     /score="136.2"
                     /tool="antismash"
                     /translation="VMRITLKAYDHQLVDQSAGKIIETVKKTGSQVSGPVPLPTKKEVV
                     TILRAVHKYKDSREQFEQRTHKRLIDITAPSQKTVDALSRLEMPAGVYIDIKM"
     PFAM_domain     21073..21357
                     /aSDomain="Ribosomal_S10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00338.24"
                     /description="Ribosomal protein S10p/S20e"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg12_84_0022"
                     /evalue="5.10E-32"
                     /label="ctg12_84"
                     /locus_tag="ctg12_84"
                     /protein_end="101"
                     /protein_start="6"
                     /score="110.1"
                     /tool="antismash"
                     /translation="RITLKAYDHQLVDQSAGKIIETVKKTGSQVSGPVPLPTKKEVVTI
                     LRAVHKYKDSREQFEQRTHKRLIDITAPSQKTVDALSRLEMPAGVYIDIK"
ORIGIN
        1 tctctaccaa gatgctgctg gcattctttg tgatcaacat catcctgatg gagacagagc
       61 ggatctgcat acgtctgttt cttcattccc ttcggaccaa cggatataac cagaagcatg
      121 tactgctcat tggatacagc cgcgcggccg aggggtttat tgacagggtc agtatgaacc
      181 cggagtgggg ataccatgta caggggatcc tggatgacaa tcaaaagccg ggttacagat
      241 acaggaatgt tcagatcctg ggtcccatgg atcatctgga gacatttctt gcctccaata
      301 ccctggatga gatcgccatc actctgagca tcaaggaata cgctaatttg gagcccatcg
      361 tggctgcctg tgagaaatca ggcgtgcata caaagtttat tcccgattat aataatataa
      421 taccaaccat accttatatg gaggaccttc agggacttcc ggttatccat atccgccatg
      481 tgcctcttac gggcgtgttt aatgcaacga tgaagcggat cgtggatatt atcggcgccc
      541 tgtttggtct gattgtattt tcgcctgtca tggtgctgac agctgtgctt attaagatca
      601 catcccccgg tcctgtgatc ttcagccagg agcgcattgg tcttcacaat catcccttta
      661 ggatgtacaa gttccgttcc atggaggtcc aggacccggg aaaggagcgg ggacagtgga
      721 ctacgcccca cgaccccagg gtaacttccg tgggccgttt catacgtaag acaagcattg
      781 acgagacgcc gcagtttttt aatgtcctgg ttggggacat gagcctggtg ggaccaaggc
      841 cggagaggcc cctttttgtt gagaaattca aggaagagat tccgcgttac atgatcaagc
      901 accaggtacg ccccggactg accggctggg cccaggtcaa tggataccgg ggagacactt
      961 ccattaccaa acgaatcgaa catgatctgt attatattga gaactggagc ctgggttttg
     1021 attttaagat tatgttttta actgttttta aagggtttat taataaaaat gcatattgat
     1081 atgcattccg tatacattta aaatactccc agcatcttgg ctgagcatga accgggcaag
     1141 atctggagcg tgtctggaaa tttttttctg gcagcgacag ccgggcttgg accgggctac
     1201 atgatagaat gaggatagac gaatgaatcg tgattttgag aatgaatttg gacaggaaga
     1261 tgagagattg agaagccgca gccggcgccg ggattcaggt gctggttctg gggctgattc
     1321 agatacagct tctgccagac gccccagatc cggcccggat gatgccggta tggaccggcc
     1381 tgccgcgaaa ccgcgcagac ctgtgtccgg gacatcacgg gtacggccgg aacaggcgga
     1441 gacagagggg agaaggatag cgggggcacg cccggagggg aatgtcagaa gcagggcggc
     1501 aggggcccgt ccggtatccg gaaacggttt ggaaagccgg cccgggacag cccggtccag
     1561 gagaccggaa ggcgcaggaa tgccgggaag cggaaccagg tcgtcaggcg caacagcgcc
     1621 aggcagcggg ggcagaccgg cgggaagcag agccggggcg gaaaccggaa ccaggccggc
     1681 gggagccaga gccggggcgg aaaccggaac caggccggcg ggagccagag ccggggcgga
     1741 aaccggggcc aggccggcgg gaaccagagc cggggcggaa accggaacca ggccgaccgg
     1801 agccagagcc ggggcggaaa ccggggccag accggcgggg accagacggg aaagccgcat
     1861 ttatacaccg gaggtcaacc tggcagatga cagggcatcc ggcgccagag gggcatccct
     1921 tcgcaggaac ggcaaggata tatcggaccg cagcgccgcc aaggagactg ctgcaacaga
     1981 taaggcagca ggcgagacga agaagtttta caggatcatg ctgatcacca tgatcgttct
     2041 ggagtttctg atcatcctgc ccgggatttt cgtgaccaga cagtttctta aaaaatataa
     2101 tatgctccag agagatccca agtttaatat tgagcaggaa accaacccta acctgaatgt
     2161 ggataaggtt gccaatatga agggatactg gacggttgcg ctttttggcg tggacagccg
     2221 gaacaattcc gttggaaaag gcaataacgc ggatgttatc atcattgcaa atgttaacca
     2281 ggaaaccagc gaaatcaagc tggtcagtat tttcagggac agctatctga atctggatga
     2341 tgaaggttcc tataacaaga tcaaccaggc ttatttcagg ggagggccgg agcaggcgat
     2401 caaggccctg aacaagaacc tggatataca gattgacgat tacgccacct ttaactggaa
     2461 ggcggtggcg gatgccatca atattctggg cggcgtggat gtggaattga gcaaggcgga
     2521 attttattac attaatgctt acattacgga aaccgtggag gccacggggg ttgcatccca
     2581 gcacctgaag tctgcgggag taaaccattt ggacggggtc caggcagttg cctacgcgcg
     2641 tctgcgcaag atggatacgg actttgcccg tacggagcgc cagcgggaga tcatacagaa
     2701 gtgttttgac aagctgaaga cagcggattt cgcagtgatc aacaacgtta tggaggttgt
     2761 attcaaacag atccttacca gtgttaccct ggatgatata atcccggcag ccaagagcct
     2821 gacaaaatat accattgcgg atacggtagg atttccaatg cagagaagtg atgccaatat
     2881 gggcaaaaag ggcgactgcg tcattcccca gaccctggag agcaatgtga tcgcactgca
     2941 tcagttcctg tttgatgatg atgattacca gcccagtgac atggtaaaga agatcagttc
     3001 caagatatcg gctgattcag gtatgtacaa tgaaggaaaa tatatagaca aggtaggtac
     3061 tgacggcgga tatataccaa agcccacaca gagtacgacc caggccgcgg agactaccac
     3121 taagagcgaa gaggaaggta cggatgttag tacctccgag atcgatgagg gaatcattga
     3181 cggtgagaac gagtgggatc ttgagaccga tgagttcggg gatatcattg acccgccgga
     3241 ggatgaaagt cctggttccc atccggggac aacgcggccg tcaggtacga cccgtccaag
     3301 cggaagcagc tcagccacta ttccctatcc gggttatacc acctctccgg ctgatgaaag
     3361 cagttcatcc ggtgtgtatc caggctccac cacgtcaccc ggcagtgaag tgaccgggcc
     3421 aggctctacc acggccgcgt atccgggcag taccaccggg acctcggcat cctatccggg
     3481 cagcaccacc ggaacctcag ccgcgtatcc gggcagcacc actactacag agggatatgt
     3541 tcccgaagga ccgggctctg tgatcatcgg accgggaaat taacctttac cggatacctt
     3601 tatccaatgt aaaataaggg ggccagcagg ttcactgtaa tttatgacag tgccggctgg
     3661 tcccttttta gtattatata agaaaatggt cacatattta tcacaaatca ttgatacact
     3721 ctattcagaa tcggaagata tgcgtgcaaa tcaggaaagg ggatatatga atgtacgata
     3781 atgatcagga atacggttgg aaatcatacg ataatcaggg atatgaaggc cgtccatata
     3841 atgaaccgca gtttgaccag ggacccaatt ttaatcaggg gccgtcaggg ggccagggac
     3901 cattgggagg ccaaggacca ttgggaggcc aaggaccatt gggaggccgg ggaccattgg
     3961 gagaccaggg accgtccgga gaccggcgtc ctccaaagaa aaggggcgga ctgttaaaaa
     4021 aagcagcttt gatcacagca ggagcggtcc tgttcggagg tgtttcagga ggcgtcatgg
     4081 tgggcgtcca tgtggctgct tcaagatacc tgaacattta tgcttcagca gatccttccg
     4141 gcaaagaaaa cggagatcag ccggttccag gcccggataa cggccagatg gacggaaaag
     4201 ggcagaatgg gcaaagcggc cagggcggat cagggtccca cgagaaagtt cccaactcag
     4261 gagggggagg agtggcggat gtgtctgata ttgtggaagc ggccatgcct acggtggtag
     4321 ccattaccag caccactgtt taccagagca ataattacgg ctatggatgg tttttcggcg
     4381 gtccccagac ctatgaagtc cccagctcag gatcggggat catcataggg gaaaatgacc
     4441 aggaactgct cattgtgact aataaccatg tggtggagag tgcctcctcc atgaaagtgg
     4501 catttataga taacgaggta gtggatgcag tgatcaaggg aacggatgcg gagacggatc
     4561 ttgcagtgat ctctgttcct ctggaccaga tcaaagcaga tacaaagagt aagatatccg
     4621 tagccaaact gggaagttca gatgacctaa aggtggggca gggcgtgatc gccatcggca
     4681 atgcgctggg atacggccag tccgtgaccg tgggatatgt gagcgccctg gaccgtgagg
     4741 tgcgggtatc caacaatgcc accagaaccc tgctgcagac tgatgctgcc attaacccgg
     4801 gcaacagcgg aggcgccctt ttgaatatga agggggaagt ggtgggaatc aatgcagcca
     4861 agtattcgtc cacagaggtg gaggggattg gatatgcgat ccccatttcc aaggcccagg
     4921 atatcatgag ccagctcatg aacaggaaga ccatgaatcc cgtggaggag gcaaagcggg
     4981 gatatctggg aatccagggt actacggtag atgaggagac ggccagcctg ttcggcatgc
     5041 ccaggggagt ctatgtatac aaggtcctgg gagacggggc ggcggctgaa tcggatttaa
     5101 gggataagga catcataaca aaggtggatg gacagtctgt caagaccatg acagaacttc
     5161 aggagctgtt agcctgttat gaactggggg aagagctgga gcttacggtc cagacccagg
     5221 aaaacggaca ataccaggag cgtattgtgc aggtgaccct gaagtccatg cctcaggaag
     5281 aacaaagcaa tcctgcacag taagttaaat ttttaaaaac aatatgaaat gaaaatgctt
     5341 cctcttgttt ggggaagcat tttgttatat acttatccca atggcagaag acggccagag
     5401 aggccctgga accacgcagg gatgcttgtt acagagagga gaactgactt ggacgacaaa
     5461 gactataccg aagatgtgaa accatccggt caagataaag aagataataa ggaagatgac
     5521 aaatatgaga aggtctgcta tatgtgccgc aggcctgaga gcaaggccgg ttccatgata
     5581 tccatgcccg ggggaatgaa cctgtgtcat gattgcatgc agaaagcttt tgattcggtg
     5641 acaaagggag gcatggattt ttccaagttt tccaacatgc cgtatatgaa tatgaacctt
     5701 aatgacctga acgtaacccc tcccgcggtg gagatcccaa agaaacaaaa gatcaagaaa
     5761 aagtcccagg aacagccggt ccttaccatg aaggacatac ccacgcccca tgtgatcaag
     5821 ggaaaactgg atgagtatgt gatcggacag gaaaaggcaa aaaaggtggt ttcagtggcc
     5881 gtttacaacc actacaagcg tgcttttttg gacggtaagg cagggcaggg agagggaaat
     5941 gcggaaaatg ccgagccgga tgatgtggtg attgagaaat ccaatatcct gatgatagga
     6001 cccacgggaa gcgggaagac ctatctggta aagacattgg cccgcctttt ggacgtgcct
     6061 cttgccattg cagacgccac ctccctaacc gaggccggat atatcggtga tgacattgaa
     6121 agcgtggtct ccaagctttt ggccgctgct gataacgatg tggagagagc ccagcggggg
     6181 atcatcttca ttgatgagat cgacaagatt gccaagaaaa agcagacaaa caccagggac
     6241 gtcagcggtg agtccgtgca gcaggagctt cttaagcttc tggagggaag cacggtggaa
     6301 gtgcctgtgg gctccaacca gaagaatgcc atgactccca tggcaaccgt gaacacggat
     6361 aatatcctgt ttatctgcgg aggagcattt ccggatctgg aggagatcat taaggaaagg
     6421 cttaagaaaa agtcctccat gggatttggc tctgtcctca aggatacata tgacagtgat
     6481 cccaatatac tgagccatgt aaccaatgaa gacctgcgca ccttcggtat gattcccgag
     6541 ttcctgggaa ggctgccggt gacagtgacc cttcaggggc ttacagagga tatgatggtc
     6601 cgtattttaa aggaacccag gaatgccatt accaagcaat atgaaaagct gctgtccatg
     6661 gacgaggtca ggcttgtgtt tgaggatgac gcccttatgt ggattgccga agaagcactg
     6721 aaaaggggaa ccggcgcaag ggctcttcgg gcaattctgg aagagtttat gctggatatc
     6781 atgtatgaga tacccaagga ccccaacatt ggttctgttg tggtgacacg tccttacctg
     6841 gagaagaacg gcggaccgct gatccagatg agaggatgag aatgaagttg aggatgggag
     6901 gacggtcccc aggacggccc ggtgcggcaa accggcagtc taaggggaat ttactcccgt
     6961 aaccgtaaaa atgtttcata tagatccagg gctccgtatc cccactccct gttgggatac
     7021 gacagcgctg gatttcttct tgccccccgg atcaggtaag ctttgatgga ggcctcactc
     7081 atggtaatat tatttccttc cacaattccc catcctaaaa gattggcagc agcgccggca
     7141 acgtgtgcgg cggcaaccga ggttccggtc ctggtggtca tgggaacgga ggttccaatc
     7201 ctgcgcccga tggcaggtcc gcttacatca acgcccgggg ctgccagatc cggcttgatc
     7261 agtcctccca ccgtgtatcc gcggctggag tgaatgtaga tgctgttgtt cagatggttg
     7321 taggcgccca ctgtgatggg agaaggggca tttcccggaa gcgtgatggt ggtgtaagga
     7381 ctgggagtca ggaacacggt ttcctccgag atcaggttgt gggtgggaag ccacatgtta
     7441 aattggcctg taagaaactg ggtattgtat acgcgtattt tccagattcc ggtcgtgggg
     7501 gcttcaaaac gcataaaaat aagctgcctt cccgaccccg cttcaatcag ctggtaattc
     7561 acggtaatga ccgtgggttc caaaaggaaa gggatagagg tttcatttcc ggctataata
     7621 ggaatacggc ttatggtttc cccgctgggg gaaagaaatc caacggaata tgtgtcaatg
     7681 gtggaggccc acagctcaac cacgaatccc cgctgggatt ccggctgccc cacgcggatc
     7741 tccacatcaa cagaagactc tcctgtgggt atggtgccca tgtagtgatg accccgccct
     7801 gtctcattgc ctgctgcaat aacagttgcc gtgcccagat accggctgat gtcctggagc
     7861 attacgctga gaggggatgt tccctcgtgg ctgcccagat tggagccaat gccgagaagg
     7921 atgaccaacg gttttccgcg gctgaatgcc tccacgcgca gatacttgat tcccatcatg
     7981 atatcatttt cctggtaagc gtcagcatcg ctgctgacaa ggtagaaatc gcgcagatat
     8041 tgtttggcag gttttagctt gacgatcagc agttcgcatt ccggggcggc tccggtaaaa
     8101 tcttcctcag gcaggaagcc gccggcggca ataccggcca gaaaggttcc gtgtccattg
     8161 gtgtccgtag atgggaccag ggcaagtgga tcatcggatt ccagggcctg gttgatctgt
     8221 tccctggtat actctgtgcc ataggtcgct ccgctggcat tataccggtt gggtacgccc
     8281 ggcggaatca gggttttatc ctccggcagg ctctgatccc agatgctgtt gatcctggtg
     8341 gtcccgtccg gattccggaa caggggattg gtatagtcga ttcccgtgtc aatgatgcca
     8401 atgagtacac cgcgcccccg gttgcccagg gcaggggatg aatgggtgga aaggataccg
     8461 gaagcttcca tgctggaact gtctaaaagc gtgtacagtc cggggatact gtagtaggaa
     8521 gtccgcctta atgatatggg ttccacagtg tccaagggag tatatataat actgaagtca
     8581 gtgcttacaa agtccataca gggaatgtct tccgggttac cgataatttg ctgctggctt
     8641 ccgtaacggt agataaagtc agcaatggtt tctgaggctg agttaaaagg gcagtctgcc
     8701 atgacatacc tcgtacaggg tatttgctat tattatatgc tgaattttag aaacctttca
     8761 ctggacggca gtgtgaaacc atagtagaat gaaagaaaag cgtggaaagg aaggcggaca
     8821 tatgatttat ggttggataa taggcggtct ggcggcgctg gatcttggca taaaaagtgt
     8881 gatcgaaagc gaggaggatg atacatttcc aagagatctg ccctcagcca agggcctgat
     8941 caaggttcac aagaatcaca acgcaggttt tccctttgga tttatgaagg agcggccgga
     9001 actggtcaaa gggattccgc tcatggtcat ctcagccatg gccggcgccc tgtgcgccct
     9061 gctccaggac aaaggaaaga cagcccagaa agcggggatt gccattatca taggcggagc
     9121 tatcagcaat ctctacgaca gagtggtccg gggctatgta gtggattatt tttccatcga
     9181 atgggagccg atcaagaaag tggtattcaa tctgggagac atgttcgtat ttctgggaag
     9241 cacgatcatt atgctggagc agacagcaaa aagcctggcc gaggtcagga aaaagaaata
     9301 ggtaagaaaa atagataaaa agtacaagga aaaataagta aagaaacaca aacgaaagaa
     9361 gaccgcagtc tccccaagac cgcggccttt ttctgaccgg cgatttaagt ggtgaagggg
     9421 gagcggtaca gcagtgggtg agaggaatgg atgtacctat cccccccacc caccccccaa
     9481 gtcccccctt aactgatcat tcccccaatg gttccgccca gggcgcatac gcccatgact
     9541 gtcacggaac gttccatatc aattggtgaa cccatgttca tggcccagga tacagcgaac
     9601 aggaccacaa aatagaacag accggccaga agcccccaga agaaccggcg ctgcctgatc
     9661 ccttttccgg caacaaaacc gcctgccaga caggtgataa agtaaactgc atacaccatg
     9721 aggtttacct gtccctcttt caaatgcagt ttatacaggg caaatgccag ggcggccagg
     9781 aggattccgg acagcacgta ggaaatgagc agggagcgga ccatgggctt aacgatacca
     9841 ttttccatag gattattctc cttcataaga atctatgttg cagtatattc ccggaggcgc
     9901 cgtgaatatg acaaaccttt gtaatttacc gttgcaaggg gctttaacct gtgttataat
     9961 ttcaaggaat tatattttgg ataagaggag gtgccgtaat atgaagcacg ttaagacatt
    10021 gaatacgaat accttgaagg ataccatgaa aaagggcgga tgcggcgagt gccagacttc
    10081 ctgccagtca gcatgtaaga catcctgcac cgttggaaac cagagctgcg agaacgctaa
    10141 ccgctagagt gtattttata aacacacgtt agcattgctc agacagatca aagatacgta
    10201 aggaaatttg gtataaagcc cctatggtcg ctgggattat aggggctttg ccacgcaaag
    10261 ggatgggccg gtactatgac aatggggagt gtgatcgatc aataccccct gccgcaccgc
    10321 aaaaggcccc ttagaaagag agagtagatt cgtgattcat caatttatta ataatggtta
    10381 ccatattata ctggatgtga acagcggttc cgtccatgtg gtagaccctg tcgtatatga
    10441 cgcagtggcg gtggtgtcag agctggttcc ggagatggaa aagcctgaac ccttgtcttc
    10501 caaggtcaag tctgatgtat ttgaccgcct gtggggcaaa tacacacccg aggagctggg
    10561 agaggccctt gaggacatcg aggagctgat cgccatggag cagcttctta caaaggatat
    10621 ttaccgtgat tttgttgtgg attttaagca gcgcaagaca gtggtcaagg ccctttgcct
    10681 tcacattgcc catgactgca acctggcctg cagatattgt tttgcagagg aaggggaata
    10741 ccacggccgc cgtgccctga tgagctatga ggttggcaaa aaggccctgg atttcctcat
    10801 tgccaattcg gggaacaggg agcatctgga agtggacttt tttggcggtg agccgctgat
    10861 gaactgggac gtggtgaagc gcctggtgga atacggccgt tcccaggagg cggagcacca
    10921 taagaaattc cgttttacca tcaccaccaa cggcgtgctt ttaaatgacg agatcatgga
    10981 tttctgcaac agggagatga gcaacgtggt catgagcctg gacggacgca aggatatcaa
    11041 tgataagatg cgccccttcc gcaatggcag cggcagctat gacctgactg ttcccaaatt
    11101 ccagaaattc gccaaaagcc gcggccagaa ggactattat gtgcggggga catttacaag
    11161 gaacaatctg gattttgcag aggatgtgct ccactatgcg gatctgggat ttgagcagat
    11221 gtccatggaa cccgtggtat ctgatccggc tgaggattat tccatccgca gagaggatct
    11281 tccggccatc cttaaggagt atgacaagct ggccctggaa tatatcaagc gcaaaaaaga
    11341 gggaagggga tttaacttct tccattttat gctggatctg aaagcaggcc cctgtgtggc
    11401 aaaacgtatg gcgggctgcg gttcaggcac cgagtacctg gcggttaccc catgggggga
    11461 cttctatccc tgccatcagt ttgtgggcaa tgaagaattt ctcatgggaa atgtggacac
    11521 cggtattgtg aacacggata taagggatga atttaagacc tgcaacgtgt atgccaagga
    11581 aggctgcaag gactgttttg caagattcta ctgcagcggc ggatgttcag ccaatgcata
    11641 caattccagc ggatccatta acggcgctta cgagatcggc tgcgagatgc agaaaaagcg
    11701 tattgagtgc gccatcatga tcaaagctgc tcttgcagat gaagaggctg aataatatga
    11761 aatatcaggt tataacaaag gaccaaaaag caaagcgggc cagaatggag accgtacacg
    11821 gcgttataga aactccggta ttcatgaatg tgggaaccgt gggcgccatt aagggcgcgg
    11881 tttcaaccga tgaccttagg gagatcggca ctcaggtgga actgtccaac acctaccatc
    11941 tccatgtgcg cacaggggat aagctgatca aagaatttgg cggacttcac aaattcatga
    12001 gctgggacag acctattctc acggattccg gcggatttca ggtgttttcc ctgaccaagc
    12061 tgcgcaagat taaagaagaa ggcgtttatt ttaactcgca tatagacggg cataagatat
    12121 tcatgggacc ggaggagagc atgcagatcc agtcaaatct gggttccacc attgccatgg
    12181 catttgatga atgtcctccc agtcatgcca gtgatgagta tatccgccag tccgttgacc
    12241 gcaccaccag atggctggcc cgctgtaagg aagagatggc ccgtttaaac ggactgccgg
    12301 acaccgtgaa cagggaacag ctgctgtttg gaatcaacca gggcggtgtg gtggatgaga
    12361 tccggatcca gcatgccaag accatacggg agatggacct ggacggctat gcggtgggtg
    12421 gacttgctgt gggggaaagc catgaggaaa tgtaccacat cctggatgtg accgttcccc
    12481 atctgcccga ggacaagccc gtttacctta tgggagttgg aaccccggcc aatatcctgg
    12541 aagcagtgga ccgcggagtg gatttcttcg actgcgtgta tccgtccaga aacggacgcc
    12601 atggccacgt gtacaccaac catggaaaac tgaacctgtt taaccagaaa tatgagctgg
    12661 acagcaggcc tattgaagaa ggctgcgggt gcccggcgtg cagatcctac agcagggctt
    12721 atatccgcca tctgctgaag gcgaaagaaa tgctgggaat gagattatgc accttgcata
    12781 atttgtattt ttataataca atgatgaaag agattcgcaa cgccatcgag gagcaccgct
    12841 acagtgagta caaagcggcc aagcttgcag gcatggagag ctctctaaag gctaatgaat
    12901 aattaactac tgtggcgagg cggcagtaga tgtgaaggag gaagtgagaa tgaatacaag
    12961 tagtccgata ttctggattc tctatattgt tcttctgggt ggtatgttat attttatggc
    13021 aatccgtcct cagaagaagg agaagcagag acagcaggag ctgttaaaca gcgttgcagt
    13081 aggagatacc atactgacca gcagcggatt ttacggtgta atcatcgata tgacagatga
    13141 tactgtaatc gttgaattcg gcaacaacaa gaactgccgt attcctatgc agaaggctgc
    13201 cattgctcaa gttgagaaag cggaagccta acatgacatg aaacccgggg cattgtcccg
    13261 ggttttctgt atataagatt acacagtcta taagatctta cagtctataa agttttgcag
    13321 tctataaaat ttagcagtct tccaggaggt aaattggatg attaaacata tagtctttga
    13381 tatgggacag gttctggtaa gttacgtggg agatctggtc tgccagaagt acatagagga
    13441 tgaacaggag aggaaggaag tgagcacatc cgtatttgtg tccccggagt ggatccttct
    13501 ggacatgggt gtcatgccgg aggaggaggc ccttaagaaa atgcaggacc gcctggacac
    13561 ggagcacaag cgggatatgg ctgcctggtg cttttggcat tggcacgaat acaacatgag
    13621 acctaaggaa ggaatggagg aagtggtaag atggcttaaa tccatggggt atgggatcta
    13681 tctctgctcc aatgcatcgg tgcgcctcct gacttgctat aaagaggtga tacctgccat
    13741 tgactgtttt gacggggttt tgttttccgc ggatgtccag tgcttaaagc cgcagaagga
    13801 gatgtaccag catctgtttg accgtttccg cctgaaaccg gaggagtgtt tttttatcga
    13861 tgacctgagt ctgaacatag agggggcacg caggtgtggg atggacggat actgttttga
    13921 ggacggggat gtagggaaac tgaaggaagt cctgggttcc ttaaaccgcc agcagccgca
    13981 ttttaatgag aagtagtggg aagtatggca atcaatggta agtgacggat gtttgtggta
    14041 agtatggcaa ttcttatgat ggaaatacat agaaaaagct ccgtaccaat tggtacggag
    14101 ccattttctt taggatttcg gattttcaaa aagggttgaa ggatagttgt taaatattcg
    14161 tgcatttctt atgtacttag tatagcatgc aatcctccaa aatgtttgaa tgttccttga
    14221 atagattatt aagaatttct taattcaaat atacgaaaaa ataacggccg gtcctagatg
    14281 gagagagtgc cttgcagaat cacatatctg aggcacaaaa ctcctttggc cccctatcac
    14341 cgtatttggg tgtcctgcaa ggcaacggat ggaggcgcac ttcagcgtac gcagattaat
    14401 gttaacgcgg ccagccgcca aaagatggct ggatagagac gaataaacgg cgcagcacaa
    14461 aagaatcccc cagagttgcc ctctggggga ttcactttgt ccgatggacc ataaccacat
    14521 actttagcta aatttattat aatccgagtg gtgagaaatg tcgatagcat tttcaggata
    14581 acaatcatac cgtacttatg gaaaataatt gctatataac tgcagcttcg tctttcgcga
    14641 ctgcatactg ggagatctgt tccacaaact taccactgtc tgaatgggat agaagttaag
    14701 aaccccttat aaagggggat ggcccggtct ggtacgccct ttcaggcgcc agtaccgggc
    14761 cgcgtcatct ctgactgaaa tcaatatatc acagtttggg atgaaactca atagtagtca
    14821 gataatcgta atgaagcgta atatttctta caaaaaagtt gggcttttgc gaaagaaagt
    14881 atgaagaaaa aaccgcctga gtacatccgt gcactcgggc ggtttttagt ggaagtaatg
    14941 gggctcgaac ccatgacctt tcgcgtgtga ggcgaacgct catcccagct gagctatact
    15001 tccatgagaa tattatagca cgataaattg gaaatacaag tgtttcattc ctaataatgt
    15061 aaaaaaattg cagaatattg tactttccat catattatag tattatgata tcaactacat
    15121 tggggcggat gtactctcaa agtctccccg gaacccggct ttgtggctga caagaatcaa
    15181 ctcgcaaatc tgggtgccgg agactcggag ggtacacgga tgaataaaag gaggtagttt
    15241 tttgtggacc tatatgggga tttaaggaaa atgatggatg tggcatcagg caggcgcaag
    15301 gcatccctgg tattaaaagg cgggacggtt gtgaatgttt ttacggaaaa gaccgaggtg
    15361 gctgatatcg ccattgagga cggatacata gctggcatag gggattatga gggggagcac
    15421 aatgtggacc tgtcgggccg gtacatctgc cccggcttta ttgacggtca tatacatatt
    15481 gaaagcgcca tggtgtcacc tcctgaattt gagaaggcgg tcctgcctca cggcaccacg
    15541 gctgtcatag cggatcccca tgagatcggc aatgtggccg gctgccaggg gatcgactat
    15601 atgctggaga ccaccaaaga cctggatctg gatgtgttta tcatgatgcc ctcctgtgtt
    15661 cctgccacgg ctttggatga gtcgggggct gttctgggac cggaggatct aaagccttac
    15721 tacgacaacc cgcgtgtgct gggccttgcg gaggtgatga actccctggg agtggttgcc
    15781 ggaatggatg acttgatggg gaaactcagt gatgccggca gcaggggaat ggtgatagac
    15841 ggccatgctc cgtttttgga gggaaatggg ctgaatgctt atgtgtgcgc cggggtgctc
    15901 tcggaccatg agtgttcaga tattgatgag gcgctgaaaa agcttggcag aggccagtac
    15961 atcatgataa gggaggggac cgcggccagg aacctggagg cgctgatgcc attgtttgcc
    16021 gccccttatt atgagcgctg catgctggtc acggacgaca aacaccccgg tgatctgatc
    16081 tccatggggc atattgacta tatcatacgc aaggctgttt cactgggggc ggatcccata
    16141 aaggccatta agatggggac tctccacagc gccaggtact ttggcttaaa ggacagaggg
    16201 gccgtcatgc ccggattgcg ggcagacctg gcagtgctgg aggatttaaa agatttccgt
    16261 gtgctggccg tgtataaaga cgggaaactg gcagcggaaa aaggcgtatg cattcaggaa
    16321 aaggaagaca aaagccggga gctggcatct gcattcccaa gggtatttga ttccttccat
    16381 ctggatgaaa ttacattaaa ggacctggag ttggaaaaga agggaaccat gcagcgtgtg
    16441 atccagttta agccccatga gctgctcaca caagagagaa tcctgccatg gccggatgac
    16501 gatactgccg cggcgcaggg gcacagggca cagggagtgg atctgaatga agacattgta
    16561 aaggcagctg tctttgagcg ccatttacat acaggtcata ccggcattgg ctttattgga
    16621 ggatatggac tgaagaaagg tgcagtggcc accagtgtgg cccatgattc ccacaatctt
    16681 attgtcatag gtaccaatga cagggatatg gttctggcag ccaatgccgt gagaaagaat
    16741 aaaggcggcc ttgccgtggc ggtggacgga caggtgacag gggagctggc ccttcccatc
    16801 ggcggcatca tgacccaggc ttccgtgtat gaggtggaat ctcagcttga gaaactgaag
    16861 gaacagacaa ggaagctggg gatcagcgaa gacattgatg cctttatgac acttgccttt
    16921 gtaagcctgc cggtgatacc taaactgagg atcaactcat atggcgtcat tgatgtggac
    16981 cggcaggagg ttgtggaggc agtcttttaa acacccatgg atctataaaa attaattttc
    17041 cttttcacaa cggtattttc ccgggactgc gggcggcgca gtggaacgca attcattttc
    17101 ccggaatatc ctaataaaaa aaggagaata tcgtgatgtg aatcaggcaa gagaagacat
    17161 aaattgtgac atcgtatatt ccatgggaat cacggggaaa ggggttggtg ttgcagtcct
    17221 ggacaccggc gtttatctcc atgaggattt taaggataga gtaacagcct ttgctgatta
    17281 tgtaaaccag aggccgcagc cctatgacga caacgggcac gggactcata tatcagctat
    17341 gataggaggg agcggcgctt cctcggaagg aaagtacaga ggggtggcgc ctggatgcag
    17401 tctgatatct gtaaaggtac tggatcacaa gggaaacgga tatgcctcgg atgtactggc
    17461 aggattaaaa tggatcaggg agcacatgca ggagtacggc atccgcattg tgaacatttc
    17521 agtgggctcc ctttccagac gtgatatgac ggagaactcc atattggtga ggggagtcaa
    17581 tgcggcctgg gatgatgggc tggttgtggt agtggcagcc ggcaaccatg gtccgggccg
    17641 tatgaccatt accacaccgg ggatcagccg caaggttatc acagtgggat gctccgatga
    17701 ccataaggaa gtggaagtga tgggaagccg gatggtggat tattccggcc gcggtcccac
    17761 tttggcatgt atctgcaagc cggatattgt ggctcccggg tcggggatcg tcagctgctg
    17821 caatgagccc ggccggtatt tctcaaagtc aggaaccagc atgtcaacac ctctggtatc
    17881 cggcgccatt gcacttttac tggaaaagta cccggaaatg agcaacaagg atgtgaagct
    17941 gcgcatccgt gaacgggccg tgaacctggg ccttccccat aaccagcagg ggtggggaaa
    18001 actggatgtg gcccgcctgc tggaagatta gaccagtaac agattgataa aaataaaaaa
    18061 tgcctgagcc catcgaagga tgggtatcag gcatttcacg ttccggcgcg cccgcgcttt
    18121 taggtacaat gaagaaatcg gaaacctacg cctcccagcg cccggaagcc ccgcatggga
    18181 gcaccagtcc tgactgggtt acgggaaggc ccacctcctg ggcattgacc gtaccgccaa
    18241 agcggggaat cacttccact cccagcatgt agctcagcac ggagggggcc aggcccgtgg
    18301 tgtatgagtt gatcaaaaag aacaggggct tgtctgaaag aagctgcacg cacagcttta
    18361 ccagaggatg gatggcatcc tcaattttcc agatctcacc cttggggccg cgcccgtaag
    18421 agggaggatc cattatgacc gcgtcatagc ggttgcctct gcggatctcc cgttccacaa
    18481 attttacgca gtcatccacg atccagcgca caggggcgtc cgccaggccg gaggaggcgg
    18541 cattttcctt ggcccatgcc accatgcctt tggatgcatc cacatgggta acgctggctc
    18601 ctgcttttgc ggctgccagt gtggcgcctc cagtgtaggc aaacaggttc agcactttta
    18661 tgggccttcc cgcctgtttg atcttatccc caaaccagtc ccagttggct gcctgttccg
    18721 gaaacagccc tgtatgctta aagctgaagg gcttcagatt aaatgtaagg ccattatatc
    18781 caatggacca ctgctccggc aggtcgaaga attcccactc accgccgcct ttgctgctgc
    18841 ggtgataatg gccgttcatg tgcttccagc ccttgtgggt cttaactgta tcccagatga
    18901 cctgcggatc aggacggacc agcaggtaat tgccccagcg ctccagcttt tcaccattgg
    18961 agcagtctat gacttcgtaa tcattccatt tgtcggcaag ccacataatt ataaaaacct
    19021 catttcctca atatctgatg tgataagtag cagattgcat catcccggcc gcagggttac
    19081 tgcctggatg aagtattata atacagagta tagtctaaat tgtgtgtaaa cgtcaagttt
    19141 atgataaaaa agaaaaaata cagtctatcg taaacaaatt gaaagataaa taaggttgaa
    19201 taattacggg agccttgata caatataggt taggattgca ggagtctcat actatgtgaa
    19261 tggcttcagc atgggcgagt gcagatggga agaggagctg agcatatgaa gaaacataca
    19321 gtggcagtgt gggtgctggc agcggtgctg tctttgggta cggctacgat ttctgccatg
    19381 gcggcggaag gttgggccca gtccgggagc agctgggttt actatgattc caatggaaac
    19441 cgcgtatata atgcatggaa aaagggggcg gacaaccagt ggcgttatct ggacggtgaa
    19501 ggcaatatgg ccaccagcgc ctgggttgat tccgattatt atgttgacag caatggtatc
    19561 atactcactg acaagtggtt gaaactgacc aatgatgacg gtgagtacga gtggtactat
    19621 tttggaagca gcgggaagat gatgtccgat gcctggaaaa agatcgataa caagtggtat
    19681 cattttgacg gggacggacg tatggagctg ggctggatcc tggatgatat gtactacacg
    19741 ggaacggacg gcgttatgcg gacaggatgg cagaagctgg aacccccgga tgaggatgat
    19801 gacaacaggg accgcgtcac acccgggatc gacagtgtaa cggatgatga tggaaggtat
    19861 tggtactatt tttcctccag cggcaagaaa ttcgcaccgg acagttcgga cggagattac
    19921 acggcgcgta agatagacgg tacatattat tgctttgatg agactggagc catgcagaca
    19981 ggctggaaga atgtgcgttc ctcctccaat gattccattg aggattacat gtatttcggc
    20041 gctgacggaa aggccaggat cggctggtac tccatagaac ccccggatga cctggaaggc
    20101 tatgacggtg atgtggagtg gttttatttt acaaacagcg gcaagccaag ggctgccgat
    20161 acagagcggc tgaccaccaa tgatatcgtg aaactgaacg gtaaatccta tctgtttaac
    20221 cacctgggca acccggttta cggacttaaa aaggtttata cgggttccgg ggatgatgac
    20281 tggaccacct tctatttcgg tgacaagaac aagagctgcg tgcagaaggg taagataaag
    20341 gtcacggagg acgatggcaa taagtcggat ttttactttg cggataacgg ccgcgggtac
    20401 aatggcgtga aggataacta cctatattat aaaggaaagc tccagaaggc cacggacggc
    20461 cagaagtacg tgtgctaccg ggtggataat aagaactatg tggtcaattc ctccggcaaa
    20521 gttatgaaga gcacaaaggt aaagaacagt gacggggtaa agtttgttac caatgccagc
    20581 gggcagctga catcagcgga tgaagatacg gatattgatt cctatgtaac agaacccatg
    20641 gaaccctatt gcactgagga ttaaaacatg gatcattggg aaagacttct ggtataacag
    20701 aggtcttttc tttttggccc gttggtcatt gaatcagtat cataaatagc aatgcagata
    20761 actatgcaga aaaaaataaa aaagtacttg catttaatgg agatgtatgc tatcataaca
    20821 aggctgtggc atgatagcgt tgaagcgaga ggttgccgcc cacaaagtga ggcgggtttt
    20881 ccgtggagcg aatgtcaagt taggaaactg gcgacaagtc actgtaccaa ttaaagaaac
    20941 tgcaggataa atggcagaat cagtgtggag ttccgttggg acacacacgg aaacgtgtac
    21001 agtcaccgct tgtcgtactt ggtttagaag tgcgaaaagg aggcgacttt ttttatggca
    21061 agtcaagtaa tgagaatcac tttaaaggct tatgatcatc agttagtaga tcagtccgcc
    21121 ggcaaaatca tcgagactgt aaagaagaca ggatcacagg tgagcggacc ggtaccgtta
    21181 ccaaccaaga aagaggtagt aaccattctg cgtgctgttc ataagtacaa agattccaga
    21241 gagcagttcg agcagagaac tcacaagaga ctgatcgaca tcactgctcc aagccagaag
    21301 acagttgatg cactgtccag actggaaatg ccggctggtg tgtacatcga catcaagatg
    21361 aaaacaaaat aatatttgtt ttcaagggaa aatgtttata tcctgaaggg tttaaattat
    21421 agaagcaaca ctgcatttcc tgttgaggaa tcaacatacc gcacccgtcc cccgggcgtc
    21481 agcaagggaa ggcttacggg caggttcata gtgttccacg tatagttaga ctgttctagg
    21541 atgaatgcga aagcattccg ctgtagatca tgaaacagga ggtaagacaa tgaagaaagc
    21601 gattttagca acaaaagtcg gaatgaccca gatcttcaat gagaatggtg ctttagttcc
    21661 ggtaaccgtg cttcaggcag gaccttgtgt ggtaacacag gttaagactg ctgagaacga
    21721 tggttacaaa gcagtacagg ttggtttcgt tgaca
//
