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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_LR699004.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 1,726,546 | 1,738,720 |
Region 2 | arylpolyene | 1,898,558 | 1,946,069 | flexirubin | Other | 44%
Region 3 | RRE-containing | 3,780,102 | 3,800,889 |

NZ_LR699004.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,726,546 - 1,738,720 nt. (total: 12,175 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.22 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.20 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.19 | RiPP | coagulin | Bacillus coagulans
BGC0000519.1 |  | 0.16 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000624.1 |  | 0.16 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000584.1 |  | 0.15 | RiPP | colicin V | Escherichia coli
BGC0000501.1 |  | 0.15 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0000551.1 |  | 0.15 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000626.1 |  | 0.15 | RiPP | thuricin | Bacillus thuringiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.55 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.53 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000617.1 |  | 0.51 | RiPP | coagulin | Bacillus coagulans
BGC0000519.1 |  | 0.47 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000624.1 |  | 0.47 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000584.1 |  | 0.46 | RiPP | colicin V | Escherichia coli
BGC0000501.1 |  | 0.46 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928
BGC0000551.1 |  | 0.46 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000626.1 |  | 0.45 | RiPP | thuricin | Bacillus thuringiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR699004.1 - Region 2 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,898,558 - 1,946,069 nt. (total: 47,512 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.28 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001075.1 |  | 0.25 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000231.1 |  | 0.23 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.22 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000838.1 |  | 0.21 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001895.1 |  | 0.20 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000219.1 |  | 0.20 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000194.1 |  | 0.19 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0001897.1 |  | 0.19 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.62 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001075.1 |  | 0.58 | Terpene, Polyketide | aurachin RE | Rhodococcus erythropolis
BGC0000231.1 |  | 0.57 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.55 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000838.1 |  | 0.54 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001895.1 |  | 0.52 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000219.1 |  | 0.52 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000194.1 |  | 0.51 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0001897.1 |  | 0.51 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR699004.1 - Region 3 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,780,102 - 3,800,889 nt. (total: 20,788 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001655.1 |  | 0.20 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001356.1 |  | 0.18 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0000794.1 |  | 0.18 | Saccharide | S-layer glycan | Geobacillus stearothermophilus
BGC0000785.1 |  | 0.17 | Saccharide | O-antigen | Burkholderia mallei
BGC0000782.1 |  | 0.17 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000774.1 |  | 0.17 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000792.1 |  | 0.17 | Saccharide | polysaccharide | Enterococcus faecalis OG1RF
BGC0000783.1 |  | 0.16 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000772.1 |  | 0.16 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0000736.1 |  | 0.16 | Saccharide | capsular polysaccharide | Mannheimia haemolytica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001655.1 |  | 0.53 | RiPP | LP2006 | Nocardiopsis alba DSM 43377
BGC0001356.1 |  | 0.49 | RiPP | paeninodin | Paenibacillus dendritiformis C454
BGC0000794.1 |  | 0.49 | Saccharide | S-layer glycan | Geobacillus stearothermophilus
BGC0000785.1 |  | 0.49 | Saccharide | O-antigen | Burkholderia mallei
BGC0000782.1 |  | 0.49 | Saccharide | O-antigen | Burkholderia pseudomallei 1026b
BGC0000774.1 |  | 0.49 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000792.1 |  | 0.48 | Saccharide | polysaccharide | Enterococcus faecalis OG1RF
BGC0000783.1 |  | 0.47 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000772.1 |  | 0.47 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0000736.1 |  | 0.46 | Saccharide | capsular polysaccharide | Mannheimia haemolytica

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names