LOCUS       c00004_NZ_JALU..       21666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JALU01000004.1 Mogibacterium timidum ATCC 33093 ctg7180000004161,
            whole genome shotgun sequence.
ACCESSION   NZ_JALU01000004
VERSION     NZ_JALU01000004
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:59:21
            Original ID  :: NZ_JALU01000004.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 43026
            Orig. end    :: 64692
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[53026:54692]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21666
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21666
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             406..1014
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101:phosphoglycerate mutase (Score: 136.6; E-value:
                     1.4e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_32"
                     /transl_table=11
                     /translation="MRLYVLRHGQTQLNSERRLQGHMQTELNDVGIAQAEMVASILNDN
                     GIKFDRIYSSPLERAIRTGEIATGVSRESFVIDHNLTEIDFGINEGRKYDELQGASGNI
                     FLSPETYLPPEGGESLESLLNRMKHFLERMRDEECEGNVLAVSHGTAIHMILLYLRGMS
                     LSELWTEHVGNCNVTVIDIDGREMKIRDDLQIATDSCIK"
     PFAM_domain     412..972
                     /aSDomain="His_Phos_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00300.24"
                     /description="Histidine phosphatase superfamily (branch 1)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_32_0001"
                     /evalue="3.40E-47"
                     /label="ctg4_32"
                     /locus_tag="ctg4_32"
                     /protein_end="189"
                     /protein_start="2"
                     /score="160.7"
                     /tool="antismash"
                     /translation="LYVLRHGQTQLNSERRLQGHMQTELNDVGIAQAEMVASILNDNGI
                     KFDRIYSSPLERAIRTGEIATGVSRESFVIDHNLTEIDFGINEGRKYDELQGASGNIFL
                     SPETYLPPEGGESLESLLNRMKHFLERMRDEECEGNVLAVSHGTAIHMILLYLRGMSLS
                     ELWTEHVGNCNVTVIDIDGREMKI"
     CDS             1113..1946
                     /locus_tag="ctg4_33"
                     /transl_table=11
                     /translation="MRAVIDVGGGTRDIFGAGVFDYFLEHEVTFDRCYGVSAGGANIAS
                     FIAGQQFRNYEFYTEYAMRKEYMSFDNFIKTGSYVDLDYVYGTLSNSYGEYPLDYEAFK
                     ENPAEFILVATEAKTGETKYFTKDDISKNNYAPLNASSCVPVVNKPYEINDVEYFDGGL
                     ADPIPYKKALEDGCDEFVIILTRPRNGRRDNAKDKRIAQVLARQYPKAAELLENRAELY
                     NEQLDAVNLLEAQGKATIIAPDSIGKLKTLTKDLDMLKNLYRKGLVAAKYAGLDS"
     PFAM_domain     1134..1628
                     /aSDomain="Patatin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01734.24"
                     /description="Patatin-like phospholipase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_33_0002"
                     /evalue="2.90E-10"
                     /label="ctg4_33"
                     /locus_tag="ctg4_33"
                     /protein_end="172"
                     /protein_start="7"
                     /score="40.8"
                     /tool="antismash"
                     /translation="GGGTRDIFGAGVFDYFLEHEVTFDRCYGVSAGGANIASFIAGQQF
                     RNYEFYTEYAMRKEYMSFDNFIKTGSYVDLDYVYGTLSNSYGEYPLDYEAFKENPAEFI
                     LVATEAKTGETKYFTKDDISKNNYAPLNASSCVPVVNKPYEINDVEYFDGGLADPIPYK
                     KA"
     CDS             complement(2165..2599)
                     /gene_functions="regulatory (smcogs)
                     SMCOG1284:transcriptional regulator, MarR family (Score:
                     74.1; E-value: 1.5e-22)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_34"
                     /transl_table=11
                     /translation="MDKYDNLKLDKQLCFPLYACSKEITRRYKPFLSKLDLTYTQYITM
                     MVLWEFRELSVKELGDKLFLDSGTLTPLLKKLESKGYLTRTRSVKDERNLIIKVTDKGM
                     ALREEALSVPQEIRACVSLTDDEAATLFRLLRRFMNTIEQ"
     PFAM_domain     complement(2318..2491)
                     /aSDomain="MarR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01047.24"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_34_0003"
                     /evalue="3.60E-15"
                     /label="ctg4_34"
                     /locus_tag="ctg4_34"
                     /protein_end="94"
                     /protein_start="36"
                     /score="55.7"
                     /tool="antismash"
                     /translation="LTYTQYITMMVLWEFRELSVKELGDKLFLDSGTLTPLLKKLESKG
                     YLTRTRSVKDERN"
     CDS             2798..3874
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_35"
                     /sec_met_domain="PF04055 (E-value: 2.4e-16, bitscore: 53.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVMKIARKLVKQGYLEHDEYARLLANRNDKVREYLRSTAQEIA
                     IENYGHDIFLRGIIEFTNTCRNDCYYCGIRKSNGKVDRYRLNPDRILHCCEIGYRIGLR
                     TFVLQGGEDPYFTDDRMCELIRGIKSKYPDCAITLSIGEKERESYERYFEAGADRFLLR
                     HETADADHYSKLHPETLSLEHRMKCLNTLKDIGYQIGAGFMVGSPGQTYDTVASDFEYL
                     HSLNPHMIGIGPFIHHDDTPFRDEPDGTVEMTLYCLSILRIMFPKVLLPATTALGTIDE
                     KGREKGVLAGANVIMPSLSPDDIRGKYLIYDGKAGVDDEAEAGRKLLDVKLAKIGYRTV
                     TERGDYKGWNRTQNSIRS"
     aSDomain        2822..3835
                     /aSDomain="TIGR03956"
                     /aSTool="tigrfam"
                     /description="rSAM_HydE: [FeFe] hydrogenase H-cluster
                     radical SAM maturase HydE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_35_0001"
                     /evalue="6.20E-162"
                     /identifier="TIGR03956"
                     /label="ctg4_35"
                     /locus_tag="ctg4_35"
                     /protein_end="346"
                     /protein_start="8"
                     /score="536.5"
                     /tool="antismash"
                     /translation="RKLVKQGYLEHDEYARLLANRNDKVREYLRSTAQEIAIENYGHDI
                     FLRGIIEFTNTCRNDCYYCGIRKSNGKVDRYRLNPDRILHCCEIGYRIGLRTFVLQGGE
                     DPYFTDDRMCELIRGIKSKYPDCAITLSIGEKERESYERYFEAGADRFLLRHETADADH
                     YSKLHPETLSLEHRMKCLNTLKDIGYQIGAGFMVGSPGQTYDTVASDFEYLHSLNPHMI
                     GIGPFIHHDDTPFRDEPDGTVEMTLYCLSILRIMFPKVLLPATTALGTIDEKGREKGVL
                     AGANVIMPSLSPDDIRGKYLIYDGKAGVDDEAEAGRKLLDVKLAKIGYRTVTERGDY"
     PFAM_domain     2972..3454
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_35_0004"
                     /evalue="2.70E-14"
                     /label="ctg4_35"
                     /locus_tag="ctg4_35"
                     /protein_end="219"
                     /protein_start="58"
                     /score="53.9"
                     /tool="antismash"
                     /translation="IEFTNTCRNDCYYCGIRKSNGKVDRYRLNPDRILHCCEIGYRIGL
                     RTFVLQGGEDPYFTDDRMCELIRGIKSKYPDCAITLSIGEKERESYERYFEAGADRFLL
                     RHETADADHYSKLHPETLSLEHRMKCLNTLKDIGYQIGAGFMVGSPGQTYDTVASDF"
     CDS             3952..5064
                     /locus_tag="ctg4_36"
                     /transl_table=11
                     /translation="MDKETRPYIAWDIVQDFMVKAFIQLGVPEADAAICADVLMESDRR
                     GIESHGVNRFKPIYVDRINKGILNPVTKVDIIRESPTTAVLDANDGIGMVAGKMAMDMA
                     VEKAGKYGTACVAVRNSSHYGIAGYWSSMATDVGMIGITGTNARPSIAPTFGVENMLGT
                     NPLTIGIPTDEGNPFLIDCATSITQRGKLEFYERTGKDTPAGMVIGRDGSALTDTSYIL
                     KALNSGEAALAPLGGIGEEMGGYKGYSYATAVELLSAALSGGLFLKNLTCFNENGELRP
                     YHLGHFFIVIDPEAMTGREVCEKTAGDILRALRASQKAPGEERIYTAGEKEWDIKEFRK
                     DKGVPMGEAVQREFIEVRDSLGINFKFPFE"
     PFAM_domain     3982..5010
                     /aSDomain="Ldh_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02615.16"
                     /description="Malate/L-lactate dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_36_0005"
                     /evalue="2.30E-114"
                     /label="ctg4_36"
                     /locus_tag="ctg4_36"
                     /protein_end="353"
                     /protein_start="10"
                     /score="382.1"
                     /tool="antismash"
                     /translation="WDIVQDFMVKAFIQLGVPEADAAICADVLMESDRRGIESHGVNRF
                     KPIYVDRINKGILNPVTKVDIIRESPTTAVLDANDGIGMVAGKMAMDMAVEKAGKYGTA
                     CVAVRNSSHYGIAGYWSSMATDVGMIGITGTNARPSIAPTFGVENMLGTNPLTIGIPTD
                     EGNPFLIDCATSITQRGKLEFYERTGKDTPAGMVIGRDGSALTDTSYILKALNSGEAAL
                     APLGGIGEEMGGYKGYSYATAVELLSAALSGGLFLKNLTCFNENGELRPYHLGHFFIVI
                     DPEAMTGREVCEKTAGDILRALRASQKAPGEERIYTAGEKEWDIKEFRKDKGVPMGEAV
                     QRE"
     CDS             5107..6123
                     /locus_tag="ctg4_37"
                     /transl_table=11
                     /translation="MIRLAINGFGRIGRLAFRRVMETDGFKVVAINDLTSPSMLAYLLK
                     YDSVQGSYLGHTVEHDEESITVDGKRITIYKEADAHRLPWEELNIDVVLECTGLYTSKE
                     KSQAHIDAGAKKVLISAPAGNDLKTVVYGVNHETLTADDKIVSGASCTTNCLAPMAKAL
                     AGYRELRTGFMTTIHAYTGNQKLLDAPDKSLKYRRSRAAAINIVPTSTGAAQAIGNVIP
                     ELAGKLIGSAQRVPVATGSITILDATLKDETDSVSVDGINAAMRAAQDQSFGYNEDEIV
                     SADVIGMSWGSLFDATQTLAQKCGTHIYEVRVVAWYDNEMSYVSQLIRTIAYMARLE"
     PFAM_domain     5110..5415
                     /aSDomain="Gp_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00044.26"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase, NAD
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_37_0006"
                     /evalue="7.00E-36"
                     /label="ctg4_37"
                     /locus_tag="ctg4_37"
                     /protein_end="103"
                     /protein_start="1"
                     /score="122.7"
                     /tool="antismash"
                     /translation="IRLAINGFGRIGRLAFRRVMETDGFKVVAINDLTSPSMLAYLLKY
                     DSVQGSYLGHTVEHDEESITVDGKRITIYKEADAHRLPWEELNIDVVLECTGLYTSK"
     aSDomain        5113..6093
                     /aSDomain="TIGR01534"
                     /aSTool="tigrfam"
                     /description="GAPDH-I: glyceraldehyde-3-phosphate
                     dehydrogenase, type I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_37_0002"
                     /evalue="2.50E-118"
                     /identifier="TIGR01534"
                     /label="ctg4_37"
                     /locus_tag="ctg4_37"
                     /protein_end="329"
                     /protein_start="2"
                     /score="393.0"
                     /tool="antismash"
                     /translation="RLAINGFGRIGRLAFRRVMETDGFKVVAINDLTSPSMLAYLLKYD
                     SVQGSYLGHTVEHDEESITVDGKRITIYKEADAHRLPWEELNIDVVLECTGLYTSKEKS
                     QAHIDAGAKKVLISAPAGNDLKTVVYGVNHETLTADDKIVSGASCTTNCLAPMAKALAG
                     YRELRTGFMTTIHAYTGNQKLLDAPDKSLKYRRSRAAAINIVPTSTGAAQAIGNVIPEL
                     AGKLIGSAQRVPVATGSITILDATLKDETDSVSVDGINAAMRAAQDQSFGYNEDEIVSA
                     DVIGMSWGSLFDATQTLAQKCGTHIYEVRVVAWYDNEMSYVSQLIR"
     PFAM_domain     5572..6057
                     /aSDomain="Gp_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02800.22"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_37_0007"
                     /evalue="3.20E-42"
                     /label="ctg4_37"
                     /locus_tag="ctg4_37"
                     /protein_end="317"
                     /protein_start="155"
                     /score="143.9"
                     /tool="antismash"
                     /translation="LAPMAKALAGYRELRTGFMTTIHAYTGNQKLLDAPDKSLKYRRSR
                     AAAINIVPTSTGAAQAIGNVIPELAGKLIGSAQRVPVATGSITILDATLKDETDSVSVD
                     GINAAMRAAQDQSFGYNEDEIVSADVIGMSWGSLFDATQTLAQKCGTHIYEVRVVAWY"
     CDS             6228..7658
                     /locus_tag="ctg4_38"
                     /transl_table=11
                     /translation="MEVKEARQYVVDRLEYAFKPDSIAVIGASRNETKVGFKVIQGLRK
                     CGYEGELYPINIKATEVAGIPAYKNINDVPEDVDLAFISLPATGVFDALKDCVEKKVKI
                     AVVSSSGFKEVGNGDLQNEITDFCREHELPLIGPNLVGIGTPYHDFNCGFIPYLPNKGP
                     VALISQSGSNLLAALGASQLDHFGISMFVGLGNKADVDFCEMIKYADNEPNTKCIAVYI
                     EALDSPEAFKKACLECEKPITAVKVGASKIGVKAAFAHTASENRGHSNAEYDQLFEESG
                     VLRENTWQEFLDTSLALGNCPPLRGDNVVIITNGGGAGLLAADHFERLGMPIKELKEIS
                     PELRDNIRSYMPAFGSPLNPVDISGTATSDMYGGALKTAYRDENVDGIMISVCPTAVTD
                     VEAITETVINIYRQYKNLGKPFIMECQGGNECRNAIMKLRDSGIPAYSTPEQAVNAMVA
                     LRRYSHIMNKKEQLIKNI"
     PFAM_domain     6291..6653
                     /aSDomain="CoA_binding_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13380.8"
                     /description="CoA binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_38_0008"
                     /evalue="2.60E-17"
                     /label="ctg4_38"
                     /locus_tag="ctg4_38"
                     /protein_end="142"
                     /protein_start="21"
                     /score="63.5"
                     /tool="antismash"
                     /translation="SIAVIGASRNETKVGFKVIQGLRKCGYEGELYPINIKATEVAGIP
                     AYKNINDVPEDVDLAFISLPATGVFDALKDCVEKKVKIAVVSSSGFKEVGNGDLQNEIT
                     DFCREHELPLIGPNLVG"
     PFAM_domain     6708..7112
                     /aSDomain="Succ_CoA_lig"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13607.8"
                     /description="Succinyl-CoA ligase like flavodoxin domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_38_0009"
                     /evalue="4.00E-32"
                     /label="ctg4_38"
                     /locus_tag="ctg4_38"
                     /protein_end="295"
                     /protein_start="160"
                     /score="111.0"
                     /tool="antismash"
                     /translation="KGPVALISQSGSNLLAALGASQLDHFGISMFVGLGNKADVDFCEM
                     IKYADNEPNTKCIAVYIEALDSPEAFKKACLECEKPITAVKVGASKIGVKAAFAHTASE
                     NRGHSNAEYDQLFEESGVLRENTWQEFLDTS"
     PFAM_domain     7152..7610
                     /aSDomain="Ligase_CoA_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19045.2"
                     /description="Ligase-CoA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_38_0010"
                     /evalue="2.00E-15"
                     /label="ctg4_38"
                     /locus_tag="ctg4_38"
                     /protein_end="461"
                     /protein_start="308"
                     /score="57.3"
                     /tool="antismash"
                     /translation="VVIITNGGGAGLLAADHFERLGMPIKELKEISPELRDNIRSYMPA
                     FGSPLNPVDISGTATSDMYGGALKTAYRDENVDGIMISVCPTAVTDVEAITETVINIYR
                     QYKNLGKPFIMECQGGNECRNAIMKLRDSGIPAYSTPEQAVNAMVALRR"
     CDS             7748..8839
                     /locus_tag="ctg4_39"
                     /transl_table=11
                     /translation="MNGDKLFRLLMILCLAMGIMGLTVGKFILGGIFIGLAVAVWLTTG
                     GKHYNDRNIYDKIVEDSEAITIEHIYERLKNLDTCLGRPWMGHNTFTKDAAINFGPSPF
                     KDFITIYKDKKNIIIKSSTELEHLVRDKASEAYFKELLDTKSMKVTPEAYSNFASWKLM
                     TTVLVDDLTEIVKALKESGEVKSGELGKFKFYYANSIDCLYKDEDDNVYTYVRTQNDPL
                     NVKIYDIPDGDDAIEESGEVLAEVTGSAKDEKSGFKFYMSGEEYGTLYRDSDSGSDSYY
                     IDTNDGRVHVEGFRAVRKANLSCNYIITIDGVRKAVIAGNARIVFEGNNLTENSLICSL
                     DNDFLLLYMAIQEFIMTKNKWLK"
     PFAM_domain     8940..9332
                     /aSDomain="Usp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00582.28"
                     /description="Universal stress protein family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_40_0011"
                     /evalue="3.40E-16"
                     /label="ctg4_40"
                     /locus_tag="ctg4_40"
                     /protein_end="131"
                     /protein_start="0"
                     /score="60.1"
                     /tool="antismash"
                     /translation="MKRILVPVDGSPRSLIALEQLKNTFSPKAFEVVLVMVRENTGYAL
                     TMAEEAEIREELDKRLTSIAKTIDNYKVITRSAIGRAGARVIEAAKECGVEMIVMTKST
                     KPGSGSSIGLTASYIIRHAQCDVMIVK"
     CDS             8940..9932
                     /locus_tag="ctg4_40"
                     /transl_table=11
                     /translation="MKRILVPVDGSPRSLIALEQLKNTFSPKAFEVVLVMVRENTGYAL
                     TMAEEAEIREELDKRLTSIAKTIDNYKVITRSAIGRAGARVIEAAKECGVEMIVMTKST
                     KPGSGSSIGLTASYIIRHAQCDVMIVKETESKKVEGYRGAVFKRAKGTVALRGQLSLKQ
                     SECLIPSVKGDVIYNIEVKRGRVRFIHRSFNGVTKEWDLPPSNGQREIYEIEAGEKVAI
                     HVNATGVGKMADRIRILNRNMKTEAVFSYEITADKGDAASDADNKAAQASVNMTTKNDN
                     STVMSDNTEPENDDVQKVDEAATADTDTVTDSHETVDFNETHEDSEADM"
     CDS             10001..10153
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_41"
                     /sec_met_domain="TIGR03973 (E-value: 9.6e-23, bitscore:
                     73.2, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 3.6e-22, bitscore: 71.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRIKTISTRNMAKTTLSGGCGECQTSCQSASKTSCSVANQHCEQ
                     AKNNR"
     aSDomain        10007..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_41_0003"
                     /evalue="2.70E-21"
                     /identifier="TIGR03973"
                     /label="ctg4_41"
                     /locus_tag="ctg4_41"
                     /protein_end="44"
                     /protein_start="2"
                     /score="73.2"
                     /tool="antismash"
                     /translation="RIKTISTRNMAKTTLSGGCGECQTSCQSASKTSCSVANQHCE"
     PFAM_domain     10007..10135
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_41_0012"
                     /evalue="4.60E-20"
                     /label="ctg4_41"
                     /locus_tag="ctg4_41"
                     /protein_end="45"
                     /protein_start="2"
                     /score="71.3"
                     /tool="antismash"
                     /translation="RIKTISTRNMAKTTLSGGCGECQTSCQSASKTSCSVANQHCEQ"
     CDS             10254..11666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_42"
                     /sec_met_domain="PF04055 (E-value: 2.2e-16, bitscore: 54.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.7e-08, bitscore: 26.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.8e-14, bitscore: 47.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.3e-20, bitscore:
                     65.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 3.2e-08, bitscore: 27.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.3e-29,
                     bitscore: 95.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIIMDVNSGAVHSVDDVAYDIIDLYDEGKSRAEIT
                     NEIRNKYEDISASDIDETLADIETLKEEKLLFSEDPFEDIAGKLKAKQSVLKAICLHVA
                     HGCNMDCKYCFAGKGEYSGKAGIMSLEVGKQALDFLVENSGARKNLEVDFFGGEPLLNW
                     DVCKELVAYGRELEKKHNKHFNFTLTTNGVLIDDDVIEFVDKECSNVVLSMDGRRQTHD
                     FMRTSKDGKGTYDRIVEKFKKLADARGQKQYYMRGTYTAYNKDFAADVLAMADLGFKET
                     SIEPVVGDSNTDYALHDEDLPMLKEQYEKLASEMLEREKRDEGFNFYHYTVDLTGGPCI
                     YKRVSGCGVGTEYLAVTPAGDLYPCHQFVGDDDFKVGNVYDGIINGDVIDGFRNNNNVY
                     TRDKCRGCFAKLYCSGGCAANNYHANGDINKVYDFGCELHKKRIECALMLKVAEEELGI
                     ERLPGASAVISY"
     aSDomain        10257..11609
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_42_0004"
                     /evalue="9.80E-218"
                     /identifier="TIGR03974"
                     /label="ctg4_42"
                     /locus_tag="ctg4_42"
                     /protein_end="452"
                     /protein_start="1"
                     /score="721.4"
                     /tool="antismash"
                     /translation="IHQYKLNGYNIIMDVNSGAVHSVDDVAYDIIDLYDEGKSRAEITN
                     EIRNKYEDISASDIDETLADIETLKEEKLLFSEDPFEDIAGKLKAKQSVLKAICLHVAH
                     GCNMDCKYCFAGKGEYSGKAGIMSLEVGKQALDFLVENSGARKNLEVDFFGGEPLLNWD
                     VCKELVAYGRELEKKHNKHFNFTLTTNGVLIDDDVIEFVDKECSNVVLSMDGRRQTHDF
                     MRTSKDGKGTYDRIVEKFKKLADARGQKQYYMRGTYTAYNKDFAADVLAMADLGFKETS
                     IEPVVGDSNTDYALHDEDLPMLKEQYEKLASEMLEREKRDEGFNFYHYTVDLTGGPCIY
                     KRVSGCGVGTEYLAVTPAGDLYPCHQFVGDDDFKVGNVYDGIINGDVIDGFRNNNNVYT
                     RDKCRGCFAKLYCSGGCAANNYHANGDINKVYDFGCELHKKRIECALMLKVA"
     PFAM_domain     10287..10451
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_42_0013"
                     /evalue="1.40E-05"
                     /label="ctg4_42"
                     /locus_tag="ctg4_42"
                     /protein_end="66"
                     /protein_start="11"
                     /score="25.3"
                     /tool="antismash"
                     /translation="IIMDVNSGAVHSVDDVAYDIIDLYDEGKSRAEITNEIRNKYEDIS
                     ASDIDETLAD"
     PFAM_domain     10551..10955
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_42_0014"
                     /evalue="8.20E-14"
                     /label="ctg4_42"
                     /locus_tag="ctg4_42"
                     /protein_end="234"
                     /protein_start="99"
                     /score="52.3"
                     /tool="antismash"
                     /translation="CLHVAHGCNMDCKYCFAGKGEYSGKAGIMSLEVGKQALDFLVENS
                     GARKNLEVDFFGGEPLLNWDVCKELVAYGRELEKKHNKHFNFTLTTNGVLIDDDVIEFV
                     DKECSNVVLSMDGRRQTHDFMRTSKDGKGTY"
     PFAM_domain     11292..11474
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_42_0015"
                     /evalue="4.80E-06"
                     /label="ctg4_42"
                     /locus_tag="ctg4_42"
                     /protein_end="407"
                     /protein_start="346"
                     /score="27.0"
                     /tool="antismash"
                     /translation="CGVGTEYLAVTPAGDLYPCHQFVGDDDFKVGNVYDGIINGDVIDG
                     FRNNNNVYTRDKCRGC"
     aSDomain        11292..11546
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_42_0005"
                     /evalue="1.20E-18"
                     /identifier="TIGR04085"
                     /label="ctg4_42"
                     /locus_tag="ctg4_42"
                     /protein_end="431"
                     /protein_start="346"
                     /score="65.3"
                     /tool="antismash"
                     /translation="CGVGTEYLAVTPAGDLYPCHQFVGDDDFKVGNVYDGIINGDVIDG
                     FRNNNNVYTRDKCRGCFAKLYCSGGCAANNYHANGDINKV"
     CDS             11885..12487
                     /locus_tag="ctg4_43"
                     /transl_table=11
                     /translation="MNKVILATQNKGKIDEMREIFSKFGMDVVSRDEMGLPKDDIEETG
                     TTFEENSYIKASTIAKQCDGIVVADDSGIAVDCIGGNPGVYSARFAGEGCTPHDNNVKL
                     LQLMDGIPADERGAKFVSVITLIYPDGKKLVARGECEGSIAEEIRGDHGFGYDPLFIPK
                     GYDKTFGELSVELKNKISHRAKSLHKLEELIREQRDK"
     aSDomain        11891..12463
                     /aSDomain="TIGR00042"
                     /aSTool="tigrfam"
                     /description="TIGR00042: non-canonical purine NTP
                     pyrophosphatase, RdgB/HAM1 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_43_0006"
                     /evalue="2.60E-59"
                     /identifier="TIGR00042"
                     /label="ctg4_43"
                     /locus_tag="ctg4_43"
                     /protein_end="193"
                     /protein_start="2"
                     /score="197.7"
                     /tool="antismash"
                     /translation="KVILATQNKGKIDEMREIFSKFGMDVVSRDEMGLPKDDIEETGTT
                     FEENSYIKASTIAKQCDGIVVADDSGIAVDCIGGNPGVYSARFAGEGCTPHDNNVKLLQ
                     LMDGIPADERGAKFVSVITLIYPDGKKLVARGECEGSIAEEIRGDHGFGYDPLFIPKGY
                     DKTFGELSVELKNKISHRAKSLHKLEEL"
     PFAM_domain     11894..12460
                     /aSDomain="Ham1p_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01725.18"
                     /description="Ham1 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_43_0016"
                     /evalue="1.60E-58"
                     /label="ctg4_43"
                     /locus_tag="ctg4_43"
                     /protein_end="192"
                     /protein_start="3"
                     /score="197.8"
                     /tool="antismash"
                     /translation="VILATQNKGKIDEMREIFSKFGMDVVSRDEMGLPKDDIEETGTTF
                     EENSYIKASTIAKQCDGIVVADDSGIAVDCIGGNPGVYSARFAGEGCTPHDNNVKLLQL
                     MDGIPADERGAKFVSVITLIYPDGKKLVARGECEGSIAEEIRGDHGFGYDPLFIPKGYD
                     KTFGELSVELKNKISHRAKSLHKLEE"
     CDS             12468..13553
                     /locus_tag="ctg4_44"
                     /transl_table=11
                     /translation="VSKEINNASNLNTENIGEGENEKVRLTKDNLVRIGFHIFRQFDDQ
                     YYAGFAAQIAYFFFMASVPTLIVLSQLLGVFDLSLDIIKNWLDHNVDSTLSSFVMGLFS
                     ASSVRLGNFVLIFLALWAASALEFSLSRLTSYTLTDGAYKFNFFKERIKAVPTAALTIF
                     AVAFTLVVFVYGEEIFSKLFKGSIFSQVLLGLRLPIVAGSFFAMITLNYYILPLVRVPL
                     RAILPGAVFSSLGILIATSIYAYYIGYATNYDILYGAFSSIVALMLWFYIISWILCIGM
                     MFNKAWDEVMERDRLSHDRMIEYIEKQSNLLGEDLYKKYFITGDDDYGTETLAVKMSRK
                     FVKGYEEELRKEKQKKARRHL"
     PFAM_domain     12615..13328
                     /aSDomain="Virul_fac_BrkB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03631.17"
                     /description="Virulence factor BrkB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_44_0017"
                     /evalue="1.50E-30"
                     /label="ctg4_44"
                     /locus_tag="ctg4_44"
                     /protein_end="287"
                     /protein_start="49"
                     /score="106.8"
                     /tool="antismash"
                     /translation="FAAQIAYFFFMASVPTLIVLSQLLGVFDLSLDIIKNWLDHNVDST
                     LSSFVMGLFSASSVRLGNFVLIFLALWAASALEFSLSRLTSYTLTDGAYKFNFFKERIK
                     AVPTAALTIFAVAFTLVVFVYGEEIFSKLFKGSIFSQVLLGLRLPIVAGSFFAMITLNY
                     YILPLVRVPLRAILPGAVFSSLGILIATSIYAYYIGYATNYDILYGAFSSIVALMLWFY
                     IISWILCIGMMFNKAW"
     CDS             13565..14497
                     /locus_tag="ctg4_45"
                     /transl_table=11
                     /translation="MKETNVNSERIDRKKLVFILNPRAGTMQANKYMVDILQTFSDAGF
                     ITSVLITAKSGDAREFAVRYANDCDVMACAGGDGTFNEMIDGVISSGAKCRIGYIPAGS
                     TNDFGASIGLSKNIIEAANSIANGEAITLDVGSFNGRFFSYVASFGAFTSTAYSVPQNL
                     KNILGHTAYVMQGIKDIVNIKSHHVKVITDEGMASERVIEENLIFGAVCNSTSVGGMIK
                     LDSFKVDMNDGLMEILLIKSPRNLLDLNSIARSILANDLDTKDIAFYSAKTVRFEMSEA
                     IPWTLDGEYEPGASVINIDTVCDAIDILV"
     aSDomain        13604..14488
                     /aSDomain="TIGR00147"
                     /aSTool="tigrfam"
                     /description="TIGR00147: lipid kinase, YegS/Rv2252/BmrU
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_45_0007"
                     /evalue="3.90E-47"
                     /identifier="TIGR00147"
                     /label="ctg4_45"
                     /locus_tag="ctg4_45"
                     /protein_end="308"
                     /protein_start="13"
                     /score="158.6"
                     /tool="antismash"
                     /translation="KKLVFILNPRAGTMQANKYMVDILQTFSDAGFITSVLITAKSGDA
                     REFAVRYANDCDVMACAGGDGTFNEMIDGVISSGAKCRIGYIPAGSTNDFGASIGLSKN
                     IIEAANSIANGEAITLDVGSFNGRFFSYVASFGAFTSTAYSVPQNLKNILGHTAYVMQG
                     IKDIVNIKSHHVKVITDEGMASERVIEENLIFGAVCNSTSVGGMIKLDSFKVDMNDGLM
                     EILLIKSPRNLLDLNSIARSILANDLDTKDIAFYSAKTVRFEMSEAIPWTLDGEYEPGA
                     SVINIDTVCDAIDI"
     PFAM_domain     13607..13975
                     /aSDomain="DAGK_cat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00781.26"
                     /description="Diacylglycerol kinase catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_45_0018"
                     /evalue="4.50E-26"
                     /label="ctg4_45"
                     /locus_tag="ctg4_45"
                     /protein_end="137"
                     /protein_start="14"
                     /score="91.0"
                     /tool="antismash"
                     /translation="KLVFILNPRAGTMQANKYMVDILQTFSDAGFITSVLITAKSGDAR
                     EFAVRYANDCDVMACAGGDGTFNEMIDGVISSGAKCRIGYIPAGSTNDFGASIGLSKNI
                     IEAANSIANGEAITLDVGS"
     PFAM_domain     14045..14488
                     /aSDomain="YegS_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19279.1"
                     /description="YegS C-terminal NAD kinase beta sandwich-like
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_45_0019"
                     /evalue="2.20E-06"
                     /label="ctg4_45"
                     /locus_tag="ctg4_45"
                     /protein_end="308"
                     /protein_start="160"
                     /score="27.7"
                     /tool="antismash"
                     /translation="QNLKNILGHTAYVMQGIKDIVNIKSHHVKVITDEGMASERVIEEN
                     LIFGAVCNSTSVGGMIKLDSFKVDMNDGLMEILLIKSPRNLLDLNSIARSILANDLDTK
                     DIAFYSAKTVRFEMSEAIPWTLDGEYEPGASVINIDTVCDAIDI"
     CDS             complement(14731..15855)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 213.7; E-value: 4.5e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_46"
                     /transl_table=11
                     /translation="MDKFYIGTLNNISEAGLGRLTDKYELTEDIDKANGIVVRSYKMHE
                     MDFSDNLMAIGRAGAGVNNIPLDRCAEDGIVVFNAPGANSNAVKELVISAMIMGARNMY
                     EGVAWANTLEGDVAGQVEKGKKQFAGTEISGKTLGIIGLGAIGAKVANAAHALGMNIVG
                     NSVVVHPILSAPCEMYDDVAEMVKVCDYISIHVPSLPETKGMINKDLIANMKEGVIILN
                     FARPDLAVNADILAGIESGKIRKYLTDVPNEELVGKAGVITTPHLGASTAEAEENCASM
                     AVDELMAYLEEGTIKNSVNFPGVELAGKAGFKKVCVLYKGEIDIEAAIKAAYGDVADVC
                     VGRSRTEYGAAIALVAADAAGELAGEGILKVREL"
     PFAM_domain     complement(15052..15573)
                     /aSDomain="2-Hacid_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02826.21"
                     /description="D-isomer specific 2-hydroxyacid
                     dehydrogenase, NAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_46_0020"
                     /evalue="7.60E-36"
                     /label="ctg4_46"
                     /locus_tag="ctg4_46"
                     /protein_end="268"
                     /protein_start="94"
                     /score="123.2"
                     /tool="antismash"
                     /translation="AMIMGARNMYEGVAWANTLEGDVAGQVEKGKKQFAGTEISGKTLG
                     IIGLGAIGAKVANAAHALGMNIVGNSVVVHPILSAPCEMYDDVAEMVKVCDYISIHVPS
                     LPETKGMINKDLIANMKEGVIILNFARPDLAVNADILAGIESGKIRKYLTDVPNEELVG
                     KAGVITTPHLG"
     CDS             16086..17177
                     /NRPS_PKS="Domain: Aminotran_5 (6-351). E-value: 5.5e-57.
                     Score: 185.2. Matches aSDomain:
                     nrpspksdomains_ctg4_47_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /locus_tag="ctg4_47"
                     /transl_table=11
                     /translation="MATNERVFNFSAGPSTLPVEVLEKAAAEMLNYEGTGESVMEMSHR
                     SAEFQQIIDDAEKNLRELMNIPDDYYVLFLQGGGTLQFSMVPINLMTGRGKADYLVTGN
                     WAKKAYEEATKFGDVKVVASSEDDLYSYIPKITPEDIRPDVDYVYVCYNNTIYGTHCNE
                     IPNVGDHMLVADMSSCILSEEIDVTKFGLIYAGAQKNVAPAGVTIVIVRKDIVGHAPAN
                     TPIYLDYATHAKKGSMYNTPPCYPIYVAGEVFKYLLRNGGVKATHERDVEKAKILYDYL
                     DKSKMFKPSVAKEDRSLMNITFVTGDADLDKKFIAGAREAGMINLAGHRSVGGMRASIY
                     NAMPKEGVETLVAYMEKFENENK"
     aSDomain        16104..17138
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_47_Aminotran_5.1"
                     /evalue="5.50E-57"
                     /label="ctg4_47_Aminotran_5.1"
                     /locus_tag="ctg4_47"
                     /protein_end="351"
                     /protein_start="6"
                     /score="185.2"
                     /tool="antismash"
                     /translation="VFNFSAGPSTLPVEVLEKAAAEMLNYEGTGESVMEMSHRSAEFQQ
                     IIDDAEKNLRELMNIPDDYYVLFLQGGGTLQFSMVPINLMTGRGKADYLVTGNWAKKAY
                     EEATKFGDVKVVASSEDDLYSYIPKITPEDIRPDVDYVYVCYNNTIYGTHCNEIPNVGD
                     HMLVADMSSCILSEEIDVTKFGLIYAGAQKNVAPAGVTIVIVRKDIVGHAPANTPIYLD
                     YATHAKKGSMYNTPPCYPIYVAGEVFKYLLRNGGVKATHERDVEKAKILYDYLDKSKMF
                     KPSVAKEDRSLMNITFVTGDADLDKKFIAGAREAGMINLAGHRSVGGMRASIYNAMPKE
                     GVETL"
     PFAM_domain     16104..17138
                     /aSDomain="Aminotran_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00266.21"
                     /description="Aminotransferase class-V"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_47_0021"
                     /evalue="2.10E-56"
                     /label="ctg4_47"
                     /locus_tag="ctg4_47"
                     /protein_end="351"
                     /protein_start="6"
                     /score="191.6"
                     /tool="antismash"
                     /translation="VFNFSAGPSTLPVEVLEKAAAEMLNYEGTGESVMEMSHRSAEFQQ
                     IIDDAEKNLRELMNIPDDYYVLFLQGGGTLQFSMVPINLMTGRGKADYLVTGNWAKKAY
                     EEATKFGDVKVVASSEDDLYSYIPKITPEDIRPDVDYVYVCYNNTIYGTHCNEIPNVGD
                     HMLVADMSSCILSEEIDVTKFGLIYAGAQKNVAPAGVTIVIVRKDIVGHAPANTPIYLD
                     YATHAKKGSMYNTPPCYPIYVAGEVFKYLLRNGGVKATHERDVEKAKILYDYLDKSKMF
                     KPSVAKEDRSLMNITFVTGDADLDKKFIAGAREAGMINLAGHRSVGGMRASIYNAMPKE
                     GVETL"
     aSDomain        16104..17168
                     /aSDomain="TIGR01364"
                     /aSTool="tigrfam"
                     /description="serC_1: phosphoserine transaminase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_47_0008"
                     /evalue="2.70E-151"
                     /identifier="TIGR01364"
                     /label="ctg4_47"
                     /locus_tag="ctg4_47"
                     /protein_end="361"
                     /protein_start="6"
                     /score="501.4"
                     /tool="antismash"
                     /translation="VFNFSAGPSTLPVEVLEKAAAEMLNYEGTGESVMEMSHRSAEFQQ
                     IIDDAEKNLRELMNIPDDYYVLFLQGGGTLQFSMVPINLMTGRGKADYLVTGNWAKKAY
                     EEATKFGDVKVVASSEDDLYSYIPKITPEDIRPDVDYVYVCYNNTIYGTHCNEIPNVGD
                     HMLVADMSSCILSEEIDVTKFGLIYAGAQKNVAPAGVTIVIVRKDIVGHAPANTPIYLD
                     YATHAKKGSMYNTPPCYPIYVAGEVFKYLLRNGGVKATHERDVEKAKILYDYLDKSKMF
                     KPSVAKEDRSLMNITFVTGDADLDKKFIAGAREAGMINLAGHRSVGGMRASIYNAMPKE
                     GVETLVAYMEKFENE"
     CDS             17164..18579
                     /locus_tag="ctg4_48"
                     /transl_table=11
                     /translation="MRTNNRIINSKNINKSLVRIMVAVLAMILVSSLMVTININTSFAA
                     SKKKAKAKTSDVTAPEIQAQSAVVFSASTNEVVFSSHRDRKLPPGSTVQLMVAMVVIDN
                     MHDDKEYKNSVQITEDMHSAGTTYPVGSSVKVEDLMYTMLMSGDAESAKALATYSAGTE
                     SNFVDQMNSKAQQLGLVNTRYTNSTGAYNTDQFSTAEDTAKIAKAAYQYGVIKQMSGED
                     RHSVKVTDGNGDKTIENTHPFMSGSSSYKGFKGGSYSKLSEPDSKEVFLASAIRNDMNL
                     IVVLFDEAPGKSTTDATKLLDYGFQKATQKVIIKKDVKIGKVRIKHGAKTRLAAYTSGK
                     GYVYIPPEGSDSLVKTESVIFDNVEAPLKAGDKVGEYRIYVADELTGTVDLVVKEDVSL
                     GWLPSYIYISNMMTVIICVILLIIVLLIVRAGNIKRRRKHMRARKHKEKIREIARQRLE
                     IEEDRKRRNWNYK"
     PFAM_domain     17329..18027
                     /aSDomain="Peptidase_S11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00768.22"
                     /description="D-alanyl-D-alanine carboxypeptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_48_0022"
                     /evalue="5.90E-36"
                     /label="ctg4_48"
                     /locus_tag="ctg4_48"
                     /protein_end="288"
                     /protein_start="55"
                     /score="124.2"
                     /tool="antismash"
                     /translation="DVTAPEIQAQSAVVFSASTNEVVFSSHRDRKLPPGSTVQLMVAMV
                     VIDNMHDDKEYKNSVQITEDMHSAGTTYPVGSSVKVEDLMYTMLMSGDAESAKALATYS
                     AGTESNFVDQMNSKAQQLGLVNTRYTNSTGAYNTDQFSTAEDTAKIAKAAYQYGVIKQM
                     SGEDRHSVKVTDGNGDKTIENTHPFMSGSSSYKGFKGGSYSKLSEPDSKEVFLASAIRN
                     DMNLIVVLFDE"
     PFAM_domain     18097..18354
                     /aSDomain="PBP5_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07943.15"
                     /description="Penicillin-binding protein 5, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_48_0023"
                     /evalue="4.40E-10"
                     /label="ctg4_48"
                     /locus_tag="ctg4_48"
                     /protein_end="397"
                     /protein_start="311"
                     /score="39.7"
                     /tool="antismash"
                     /translation="VIIKKDVKIGKVRIKHGAKTRLAAYTSGKGYVYIPPEGSDSLVKT
                     ESVIFDNVEAPLKAGDKVGEYRIYVADELTGTVDLVVKEDV"
     CDS             18617..20530
                     /locus_tag="ctg4_49"
                     /transl_table=11
                     /translation="MFNIEEELKKLPLSPGVYMHKDSLGNVIYVGKAIKLRNRVSQYFH
                     KNSQHTPKVLAMVENIAEFDYITCATEMEALILECNLIKKYMPKYNILLKDGKTYPYIE
                     VTVSEEFPRVVRTREVKRDGNKYFGPYSDSGAVSRIIKLIDEIYPVKKCKTKEFPANVR
                     PCLNYYIGKCKGICINAADKSEYDEMIESILKILNGKDAKLIKDLKGKMLEASDKLEYE
                     EAAKYRDYINAFKALGETQRATMASDRDVDVLLPLAAQNSQIVAQYKVREGKLLGREIH
                     YMDEADPELGGSGNELIEAFIKQYYTGSAKLPKEILLTEHIDEEDLVKGLLDNTNAENA
                     KAKSDTAHRTKITVPERGEKKAILDLAISDSLQVVKGLDERAERDAEKRDNLRNEITKL
                     IKRASDIEGSVPYIIEDGDDREYRIEAYDISNMNGLDTVGAMVVYEGAKPVRNDYRKFK
                     IKSADAEGDDYASLQEVIYRRLKRAKDNDAGFNRYPDIFFIDGGLGQVHAVQNVVAAFR
                     MSIPVVGLAKDDVHRTRAIIFGDGTEIELRDEPMLYSYCGRIQEEVHRFAITFQRGRRT
                     SKMTKSALEEIPGIGPARRKELLRHFKNIESIKRASYDELLECDSISSKAAENILEYFG
                     KK"
     aSDomain        18629..20461
                     /aSDomain="TIGR00194"
                     /aSTool="tigrfam"
                     /description="uvrC: excinuclease ABC subunit C"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_49_0009"
                     /evalue="2.90E-155"
                     /identifier="TIGR00194"
                     /label="ctg4_49"
                     /locus_tag="ctg4_49"
                     /protein_end="615"
                     /protein_start="4"
                     /score="516.1"
                     /tool="antismash"
                     /translation="EEELKKLPLSPGVYMHKDSLGNVIYVGKAIKLRNRVSQYFHKNSQ
                     HTPKVLAMVENIAEFDYITCATEMEALILECNLIKKYMPKYNILLKDGKTYPYIEVTVS
                     EEFPRVVRTREVKRDGNKYFGPYSDSGAVSRIIKLIDEIYPVKKCKTKEFPANVRPCLN
                     YYIGKCKGICINAADKSEYDEMIESILKILNGKDAKLIKDLKGKMLEASDKLEYEEAAK
                     YRDYINAFKALGETQRATMASDRDVDVLLPLAAQNSQIVAQYKVREGKLLGREIHYMDE
                     ADPELGGSGNELIEAFIKQYYTGSAKLPKEILLTEHIDEEDLVKGLLDNTNAENAKAKS
                     DTAHRTKITVPERGEKKAILDLAISDSLQVVKGLDERAERDAEKRDNLRNEITKLIKRA
                     SDIEGSVPYIIEDGDDREYRIEAYDISNMNGLDTVGAMVVYEGAKPVRNDYRKFKIKSA
                     DAEGDDYASLQEVIYRRLKRAKDNDAGFNRYPDIFFIDGGLGQVHAVQNVVAAFRMSIP
                     VVGLAKDDVHRTRAIIFGDGTEIELRDEPMLYSYCGRIQEEVHRFAITFQRGRRTSKMT
                     KSALEEIPGIGPARRKELLRHFKNIESIKRASYDE"
     PFAM_domain     18662..18889
                     /aSDomain="GIY-YIG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01541.26"
                     /description="GIY-YIG catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_49_0024"
                     /evalue="3.00E-07"
                     /label="ctg4_49"
                     /locus_tag="ctg4_49"
                     /protein_end="91"
                     /protein_start="15"
                     /score="30.7"
                     /tool="antismash"
                     /translation="GVYMHKDSLGNVIYVGKAIKLRNRVSQYFHKNSQHTPKVLAMVEN
                     IAEFDYITCATEMEALILECNLIKKYMPKYN"
     PFAM_domain     19223..19324
                     /aSDomain="UVR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02151.21"
                     /description="UvrB/uvrC motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_49_0025"
                     /evalue="2.90E-09"
                     /label="ctg4_49"
                     /locus_tag="ctg4_49"
                     /protein_end="236"
                     /protein_start="202"
                     /score="36.5"
                     /tool="antismash"
                     /translation="KLIKDLKGKMLEASDKLEYEEAAKYRDYINAFKA"
     PFAM_domain     19877..20320
                     /aSDomain="UvrC_HhH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08459.13"
                     /description="UvrC RIbonuclease H-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_49_0026"
                     /evalue="3.70E-44"
                     /label="ctg4_49"
                     /locus_tag="ctg4_49"
                     /protein_end="568"
                     /protein_start="420"
                     /score="150.5"
                     /tool="antismash"
                     /translation="EYRIEAYDISNMNGLDTVGAMVVYEGAKPVRNDYRKFKIKSADAE
                     GDDYASLQEVIYRRLKRAKDNDAGFNRYPDIFFIDGGLGQVHAVQNVVAAFRMSIPVVG
                     LAKDDVHRTRAIIFGDGTEIELRDEPMLYSYCGRIQEEVHRFAI"
     PFAM_domain     20375..20524
                     /aSDomain="HHH_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12826.9"
                     /description="Helix-hairpin-helix motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_49_0027"
                     /evalue="8.70E-09"
                     /label="ctg4_49"
                     /locus_tag="ctg4_49"
                     /protein_end="636"
                     /protein_start="586"
                     /score="35.5"
                     /tool="antismash"
                     /translation="IPGIGPARRKELLRHFKNIESIKRASYDELLECDSISSKAAENIL
                     EYFGK"
     CDS             20603..20884
                     /locus_tag="ctg4_50"
                     /transl_table=11
                     /translation="MSQEERNMIEEEEDIITLEFDDGTAVDCDVLGTFEADSKEYIALA
                     PIDGTDDVYIYGYKDIDPETFDIVDIDDEDEFNNAVKAFEAAMSEVDE"
     PFAM_domain     20663..20866
                     /aSDomain="DUF1292"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06949.13"
                     /description="Protein of unknown function (DUF1292)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_50_0028"
                     /evalue="2.40E-11"
                     /label="ctg4_50"
                     /locus_tag="ctg4_50"
                     /protein_end="88"
                     /protein_start="20"
                     /score="44.4"
                     /tool="antismash"
                     /translation="DDGTAVDCDVLGTFEADSKEYIALAPIDGTDDVYIYGYKDIDPET
                     FDIVDIDDEDEFNNAVKAFEAAM"
ORIGIN
        1 aatactgctg tatcatgcta agctcgattc gcagattaac gacagaaact cagatgagtt
       61 ggataagatc atcaagacga gaatggttcg tgaggagcag tttaagagca ggttcccggc
      121 ggcgtatcac gcattcgctg aggaacgggc aaggcacagg gaaattctta aaaacaagta
      181 tcctgagatt ttggagagaa tcaagagact tcgtgcggag ggcccggatg catcgcagcc
      241 gcgtgagaag ccggaacagg acaagagctc gttcccggtt cttcacgagc tggaacagtt
      301 tgttgacggg gtcaaggatt attttcacct caagaactag cttaaaaatt gcattgcagt
      361 atttatagag gctataatta tcatgtagct taagaaaggc aggatatgag actttatgtt
      421 cttagacatg gtcagacaca gctgaacagt gagcgtagat tgcaggggca tatgcagact
      481 gaactcaatg atgtcggtat agcgcaggct gagatggttg cctcgatact gaatgacaat
      541 ggtataaagt tcgataggat atatagcagt ccactcgaga gggcgattag gacaggtgaa
      601 attgcaacag gcgtctcaag agaaagcttc gtcatagacc ataatctgac tgagattgat
      661 tttggtatca acgaaggtcg caagtacgat gaactgcagg gtgcatcagg caacatcttt
      721 ctatcgccgg agacatatct gcctcctgaa gggggtgaat cactcgagtc gctgcttaac
      781 cgcatgaagc attttctgga gaggatgcgc gatgaagagt gtgaaggcaa tgtgctggca
      841 gtttcacacg gaactgcgat ccacatgatt ctgttatacc ttagaggtat gtcattgagc
      901 gagctctgga ctgagcacgt cgggaattgc aatgtgacgg tgattgacat tgatggccgg
      961 gagatgaaga taagagatga tctgcagata gcgactgaca gctgtatcaa ataacaattg
     1021 tcaggatatg ccgcggcagt ttggacaatc tgcggcgatg atatagttaa aatttgtatt
     1081 atatataaat catatgcaga agggagtaag acatgagagc agtaattgac gttggcggag
     1141 gcaccaggga catcttcgga gccggagtat tcgattattt ccttgagcac gaagtgacat
     1201 ttgacagatg ctacggagtg tcggcggggg gtgccaatat cgcatcgttt attgccggac
     1261 agcagttcag aaactatgag ttttatactg agtatgcgat gcgcaaggag tacatgagct
     1321 ttgataattt catcaagacc ggctcgtatg tagacctcga ttatgtctat ggaactctat
     1381 caaacagcta tggcgagtat ccgttagact acgaggcttt taaggagaat cccgcagagt
     1441 ttatactggt ggctacagag gctaagaccg gagaaacgaa gtacttcacg aaggatgata
     1501 taagcaagaa taactatgcg ccgctcaacg cttcaagctg tgtgcctgta gttaacaagc
     1561 catacgagat aaatgacgtt gaatattttg acggcgggtt ggctgatccc attccatata
     1621 agaaagcgtt agaggacggc tgcgatgaat ttgtaatcat tctcaccaga cctaggaacg
     1681 gacgtcgtga taatgccaag gacaagagaa tagcacaggt gctggcgaga cagtatccga
     1741 aggcggcaga gctgttggaa aacagagcag agctatacaa tgaacagctg gatgcggtca
     1801 atttacttga ggctcagggc aaggcgacga ttatcgctcc tgatagcatc ggtaagctca
     1861 agactctgac caaggatctt gatatgctca agaatcttta tagaaaggga cttgtggctg
     1921 ctaaatacgc agggctggac agctagagca ttgtgtctgt tcctgtagaa ctaaactata
     1981 ccatgaattg ggatgcggcc tcgcttgttt actaagggca gctgtatgaa ggcattgcca
     2041 atcgaagcaa ggtgcatatg taaaacaaag ctgcgataca acgaaaatag accggagcca
     2101 atcggttccg gtctgttttc gttgatgtgc gtttaatttc atttgatgtc ggtattgtta
     2161 ttttctactg ttcgattgtg ttcataaatc tgcgcagcag cctaaacagc gtggcagcct
     2221 cgtcatccgt caggcttacg caagcgcgaa tctcctgcgg tacagacagt gcctcttcgc
     2281 gaagagccat tcccttgtct gtaaccttga tgatgagatt gcgttcatcc tttacagaac
     2341 gagttctggt gagatatccc ttagattcaa gcttcttgag cagtggagtc agcgttccgg
     2401 aatccagaaa gagcttgtct ccaagctcct taacactgag ttctcggaat tcccagagca
     2461 ccatcattgt gatgtactgg gtatatgtaa gatccagctt gcttaggaat ggcttgtatc
     2521 tgcgagtgat ctcctttgag cacgcataca gcggaaagca tagctgttta tctagcttca
     2581 ggttgtcata tttgtccatc agtcttcctc ctaattgttc agacacggta tacaacatac
     2641 tctctcagaa tatcttgttg tatacaatta aatttagttt atattagttg cgttaaagtg
     2701 tcaataatta tttatgcaaa cattcaaaaa aacagtcatt ttcttttgtt gtcttaacga
     2761 agcattgtgt tagaatatta aggatgggag tagagagatg agcgaagtga tgaaaattgc
     2821 ccgcaagctc gtgaagcagg ggtatcttga acacgatgaa tatgcaaggc tactcgcaaa
     2881 caggaacgat aaagtacgtg agtatctccg cagcaccgcg caggaaattg cgattgaaaa
     2941 ctatggtcat gatatatttc tcagaggcat catcgagttt acaaatacat gcagaaatga
     3001 ttgttattac tgtggcatta ggaagagcaa cggtaaggtt gacagataca ggttgaaccc
     3061 ggatcggatt ttacactgct gtgagattgg ttaccgcatt ggccttcgca catttgtgct
     3121 tcagggggga gaggatccat attttacgga tgaccgcatg tgcgagctta ttagaggaat
     3181 aaaatcaaaa tacccggatt gcgctatcac gctttcgata ggagagaagg aaagagagag
     3241 ctacgagcgt tactttgaag caggtgcaga taggttccta ctcagacatg agaccgcaga
     3301 tgctgatcac tacagcaaat tgcatcccga aacactgtcg ttggagcatc gtatgaaatg
     3361 tctaaatacg ctcaaggata tcggctacca gataggagcc ggttttatgg tcggatcacc
     3421 cggacagacc tatgatactg tggcaagtga cttcgagtat cttcacagtc tcaatccgca
     3481 tatgatagga attgggccgt ttattcacca cgatgatacg ccttttaggg acgagccgga
     3541 tgggacagtg gagatgacac tatactgtct cagcatattg cgcatcatgt ttccaaaggt
     3601 gctcttaccg gctacaacag cgctcggcac tatagatgag aaaggcaggg agaagggcgt
     3661 gctcgcgggg gcaaacgtaa tcatgccaag cctttcgccg gatgatatta gggggaaata
     3721 cctgatctat gatggcaaag caggagtcga tgatgaggcg gaggcaggac gtaagctgct
     3781 cgatgtcaaa ctcgccaaga taggatacag aaccgttaca gagcgtggag attacaaggg
     3841 gtggaatagg acgcagaatt caattcggag ttgatcggta atcagttcac gaattgtttc
     3901 tatagatagt tatattcata gacacagatt tattcatttt ggaggtgctt gatggataaa
     3961 gaaacacgtc cgtatatcgc ttgggatatc gtacaggatt ttatggtcaa ggcgtttatt
     4021 cagcttggag ttcccgaagc tgatgctgct atctgtgcgg atgtcctcat ggagagtgac
     4081 agaagaggta tcgagagcca cggggtcaat agatttaagc cgatctatgt agatcgtatc
     4141 aacaaaggga tactcaaccc tgtcaccaag gtagatatca tcagagagtc tccaactact
     4201 gctgtgctgg atgctaatga cggcataggt atggtagccg gcaagatggc aatggatatg
     4261 gctgtcgaga aggccgggaa atacggcact gcgtgcgttg ctgttagaaa ctcctcgcat
     4321 tatggaattg caggctattg gtcatcgatg gctacagatg tgggaatgat cggaattacc
     4381 ggaaccaatg ccagaccatc catcgcaccg accttcggcg tcgaaaatat gctgggaacc
     4441 aacccgctga caatcggaat tccgacagac gagggaaatc cgtttctcat cgactgtgcg
     4501 acttcaatta cgcagagagg taagttggaa ttctatgaac gcacaggtaa ggatacaccg
     4561 gcaggaatgg taatcggtag agacggatct gcattgacag atacgtcgta tattctcaag
     4621 gctctaaatt ccggagaggc tgccctcgcc ccgcttgggg gaatcggtga ggaaatgggc
     4681 ggatataagg gctacagcta cgcgacagcg gttgagctgc tgtcggcagc tctatccgga
     4741 ggactcttcc tcaagaatct gacttgcttc aatgagaatg gcgagctcag accatatcat
     4801 cttggccatt tcttcattgt catcgacccg gaggcgatga caggcagaga agtctgcgaa
     4861 aagactgccg gagacatttt gagagcgctc agagcttcgc agaaggctcc cggtgaggaa
     4921 agaatctata ctgcaggtga gaaggaatgg gatatcaaag aattccgcaa agacaaaggt
     4981 gttccgatgg gagaagctgt acagcgcgag tttatcgagg ttcgtgactc gctcggcatt
     5041 aattttaaat tcccgtttga atagagatat ttgaaaagtt gttgaagaaa ggtaaaagga
     5101 ggctggatga ttaggttagc tattaacgga ttcggtcgta tcggcagact tgcattcaga
     5161 cgcgtaatgg agacggatgg ctttaaggtt gtcgcgataa acgatttgac ctcgccctct
     5221 atgctcgctt atctgctgaa gtatgacagc gtgcagggct cgtacctagg tcacactgtt
     5281 gagcacgatg aggagtcgat tactgtcgac ggcaaaagga taaccattta caaggaagcg
     5341 gatgctcaca ggcttccctg ggaggagctc aatatcgacg ttgtgctcga gtgcaccgga
     5401 ttatacactt ccaaggagaa gtcgcaggcc cacatcgacg caggcgccaa aaaggttctg
     5461 atctctgcac cggcaggcaa tgatctcaag actgtcgttt acggagtcaa ccacgagact
     5521 ctgacagcgg atgacaagat tgtttcggga gcatcctgca ctactaactg tctggcgcct
     5581 atggcaaagg cacttgccgg ctatagagag ctgcgtacag gcttcatgac caccattcat
     5641 gcatacaccg gtaatcagaa gctgctcgat gcccctgaca agagcttgaa gtacaggcgg
     5701 tcaagagctg ctgccatcaa catcgttcct actagtacag gagcggcaca ggcaatcggt
     5761 aacgtaatcc cagagctcgc cggcaagcta attggatcgg cacagagagt tccggttgca
     5821 acaggctcaa tcaccatcct ggatgcaacc cttaaggatg agaccgattc cgtaagtgta
     5881 gatggaatca atgcagcgat gagggcagca caggatcagt cgtttggata caatgaggat
     5941 gagattgttt cggctgacgt gatcggtatg agctggggtt ctctgtttga tgcaactcag
     6001 acactcgctc agaagtgcgg aactcatatc tatgaggtca gagtagtggc ttggtatgat
     6061 aatgagatga gctatgtgag ccagctgatc agaactatcg catatatggc aaggctggaa
     6121 tagatgcagt aactatcaag ccatacggta tcgatacctg acgatattga ccgtaaacag
     6181 caaaggtaaa tatggataat agattagttt aaggagatta tttgactatg gaagtaaagg
     6241 aagcaaggca atatgtcgta gacagattgg agtatgcatt taagcctgat tcaatcgctg
     6301 tgattggggc aagccgcaac gagactaaag ttggtttcaa ggtgattcaa gggctcagaa
     6361 agtgcggata cgaaggcgag ctatatccta tcaacatcaa ggcaactgag gttgcaggaa
     6421 tccctgctta caaaaatatc aatgatgttc ctgaagatgt agatttagcg tttatatcgc
     6481 tgccggcaac gggtgtattt gatgcactta aggattgtgt cgagaaaaaa gtcaagattg
     6541 cggtagtgtc atcatccgga tttaaggagg ttggaaacgg ggatttgcag aatgagatta
     6601 ctgacttctg ccgcgaacac gagttgccgc tgattggccc taatcttgta ggaataggaa
     6661 ctccatatca cgatttcaac tgtggattta ttccatatct tcccaataag ggtcctgtag
     6721 cacttatctc acagtcggga tccaatcttc tcgcagcact tggagcttcg cagctggatc
     6781 atttcggcat cagcatgttc gtaggacttg gcaacaaggc agacgtcgac ttctgtgaga
     6841 tgattaagta tgcagataat gaacctaaca ccaagtgcat agccgtttac atagaggcgc
     6901 tggacagccc cgaagctttc aaaaaagcct gcctggagtg tgagaaacca ataactgctg
     6961 tcaaggtcgg agcttctaag attggagtta aggctgcatt tgcacacacc gcatctgaaa
     7021 ataggggcca ttcaaatgca gagtacgatc agttgtttga agagtccgga gttctacgtg
     7081 agaacacctg gcaggaattc ctagatactt ctcttgcgct tggaaactgc cctcctttga
     7141 gaggcgacaa tgttgtgatt ataactaatg gaggaggcgc cgggcttctt gctgcagacc
     7201 attttgagag actggggatg ccgatcaagg agcttaaaga gatttcaccg gagctgcgcg
     7261 ataatatcag aagctacatg ccggcgttcg gatcgccact caaccctgtt gatatcagcg
     7321 gaactgctac ttctgatatg tatggcggcg cgctcaagac tgcatacagg gatgagaatg
     7381 tggatggaat catgatttca gtctgcccga cagctgtaac ggacgtcgag gcaattacag
     7441 agaccgtaat taatatttac aggcagtaca agaatcttgg aaagcctttt atcatggagt
     7501 gccagggtgg aaatgagtgc agaaatgcta tcatgaagct gagagacagc ggtattcctg
     7561 cctactcaac acctgagcag gctgtaaatg caatggttgc actcaggaga tatagtcata
     7621 tcatgaacaa gaaggaacag ctgattaaga atatttaatc aaaaggcatc atcgttattg
     7681 cgtaaattga gatgggcgat gcagagatgc ggataacacc cctgcatcac ctttaaaagg
     7741 gatgagtatg aacggagaca aactattcag gctgctgatg atattgtgcc tggcaatggg
     7801 catcatggga ttaactgtgg ggaaatttat tcttggcggt atttttatcg gtctcgccgt
     7861 tgctgtatgg ctgacgactg gcggcaagca ctacaatgat cgtaacatat atgacaaaat
     7921 cgttgaggat agcgaggcaa tcactatcga gcacatatac gaacgactta agaatctcga
     7981 tacatgccta ggacgacctt ggatgggtca caatactttc accaaggatg cggcaattaa
     8041 ctttggacct agccctttca aggatttcat cacgatatat aaggataaga aaaacatcat
     8101 aattaagagc agtacagagc ttgagcactt ggtgcgagac aaagcgagcg aagcttattt
     8161 taaagagctc ctcgacacca agagtatgaa ggtcacgcct gaagcatact ctaattttgc
     8221 aagctggaag ctgatgacta ccgttctggt ggacgatctg accgagatcg ttaaggctct
     8281 caaggagagt ggagaggtta agagtggaga gctcggcaaa ttcaaatttt actacgccaa
     8341 cagcatagac tgcctgtaca aggatgagga tgacaacgta tacacttacg ttagaactca
     8401 gaatgatcca ctgaatgtca agatttatga cataccggac ggggacgatg ctatagagga
     8461 atccggcgag gtgctggcag aggtaaccgg atccgccaag gatgagaaga gcggattcaa
     8521 gttctacatg tccggcgagg agtacggcac gctgtaccgc gattctgaca gcggcagcga
     8581 ttcatactat atagacacaa atgatggtcg cgttcacgtg gaaggttttc gtgctgttcg
     8641 caaagctaac ctcagctgta actatatcat tacgatagat ggagttcgca aagcggtaat
     8701 tgcgggtaat gcgaggattg tttttgaagg aaacaatctc acagagaata gcttaatttg
     8761 tagcctggat aacgattttt tgctattgta tatggcaatt caggagttca taatgaccaa
     8821 gaacaagtgg ctgaagtagc ctgatgaaat aggttcgatt gattttactg cttccaaaat
     8881 gtataatagc tgtgtatatt taataccgcg taagcggttc aataaataag gaggctttga
     8941 tgaagagaat ccttgtgccg gttgatggtt cacctaggag tttaatagcg ctggaacagc
     9001 taaaaaatac cttctcgcct aaggcgtttg aggttgtgct tgttatggtg cgtgagaata
     9061 ctggatatgc gctcacaatg gctgaagagg cggagattcg cgaggagctc gacaagaggc
     9121 tcacatctat tgccaaaaca atcgataact ataaagttat aaccagatct gcaataggaa
     9181 gggccggagc tagagttata gaggcggcca aggaatgtgg tgtagagatg attgtcatga
     9241 ccaaatccac caagccggga tccggcagca gtataggtct tactgcatca tatattatac
     9301 gccacgctca gtgtgatgtg atgattgtta aggagactga gagcaagaag gtcgaaggct
     9361 ataggggcgc tgtatttaag agagctaagg gcacagttgc acttcgtggg cagctgagcc
     9421 taaagcagag tgagtgccta attccgagtg tcaagggtga tgtaatctac aacatcgaag
     9481 ttaaaagagg tagagttaga ttcatacaca ggtcgttcaa cggtgtgaca aaggagtggg
     9541 atttgccgcc aagtaacgga cagcgggaaa tctatgagat tgaagccggg gagaaggttg
     9601 ctattcatgt caacgcaacc ggtgttggca agatggctga cagaatcaga attctcaatc
     9661 gaaacatgaa gactgaggcg gtattcagct acgagattac agccgataag ggtgatgcgg
     9721 cttccgatgc ggataataag gctgcacaag ctagtgtaaa tatgacgacg aagaatgata
     9781 attcaacggt gatgagcgat aacactgagc cggaaaatga cgatgtgcag aaagtagatg
     9841 aagctgcgac ggcggatacc gatacagtca cagattcaca cgaaactgtt gattttaatg
     9901 agactcatga ggacagcgaa gctgatatgt aatcagagag cacgttgaca cagataggac
     9961 tatttgatat tctataacga gtaattagga ggataacacg atgagcagaa tcaagacaat
    10021 ttcaaccaga aacatggcta agacaaccct ttccggcgga tgtggtgagt gccagacatc
    10081 ctgccagtcc gcgagcaaga cttcatgcag cgttgctaat caacactgcg agcaggctaa
    10141 gaacaaccgg taattgaagg tgctgctgat ggcagcgctt ttttattgcc gctctgtgtt
    10201 aagtccgctt aacacagatg aacaaaatat ataaggtatg gtgacaggaa tacatgatac
    10261 atcagtataa actaaacgga tataacatta taatggacgt aaacagcgga gccgtgcatt
    10321 ctgtagacga tgtggcttat gacattatcg atctctatga tgagggaaag tcaagagctg
    10381 agattacgaa tgagattaga aacaagtacg aggacatttc agcgagtgat atagatgaga
    10441 cattggcgga tatcgagaca ctgaaggaag aaaaactgct tttttcagag gatccctttg
    10501 aagatattgc agggaagctc aaggcgaaac agtcggtact caaggctata tgccttcacg
    10561 tcgctcacgg ctgcaatatg gactgcaaat actgctttgc aggtaaggga gaatacagcg
    10621 gcaaggcagg aatcatgtct cttgaggtgg gaaaacaggc gctggatttt ttggttgaga
    10681 attcgggtgc tcgcaagaat ctcgaagtgg atttctttgg cggtgagccg ttactcaact
    10741 gggatgtctg caaggagctt gttgcttacg gcagagagct ggagaagaag cacaacaagc
    10801 acttcaactt tactctcacg acaaatggcg tgctgattga tgacgatgtt atagagtttg
    10861 tcgataagga atgcagcaat gtcgtgctca gtatggacgg ccgtagacag actcatgatt
    10921 tcatgcgcac tagcaaggat ggtaagggca cttacgacag aatagttgag aagttcaaga
    10981 agcttgcaga tgcgaggggt cagaaacagt attatatgcg tggtacatat acagcttaca
    11041 acaaggattt tgcagctgac gttctcgcta tggctgacct cggattcaag gagaccagca
    11101 ttgaaccggt agtgggcgat tcgaacacgg attatgctct tcacgatgaa gacctgccaa
    11161 tgctcaagga gcagtatgag aagctcgcaa gcgagatgct tgagcgcgag aagcgagacg
    11221 aaggcttcaa tttctatcac tatacagttg atctgaccgg tggcccgtgc atctataagc
    11281 gcgtcagcgg atgcggtgta ggaactgaat atctggcagt aacacccgca ggagatttgt
    11341 atccgtgcca tcagtttgta ggcgacgacg atttcaaggt aggaaatgtg tacgacggta
    11401 tcatcaatgg tgatgttatt gacggcttca gaaataacaa taacgtttac acacgtgata
    11461 aatgtcgtgg ctgcttcgcc aagctctact gctcgggagg ttgcgcagcg aacaactatc
    11521 atgcaaatgg cgatatcaac aaggtgtatg atttcggatg tgagctgcac aaaaaaagaa
    11581 tcgagtgcgc actcatgctc aaggtcgcgg aggaggagct cggaattgag agattgccgg
    11641 gcgctagcgc tgtgatttca tactgatcct tcattgtaaa gcctgtgcag tgatttataa
    11701 tggttaaatt catgaaacca acaccggcac aatccataag cttgtataaa atcattaaat
    11761 aacaaatgtg atatggtata attaattcgg acattttgag actaaagaga aatattacat
    11821 atcgcgagca tgattattaa ataatctgta acaaaaaggg taatggataa ggagatatat
    11881 agtaatgaat aaagtaattc tggcgacaca gaacaaaggg aaaattgacg aaatgcgtga
    11941 gatattctcg aagttcggga tggatgtagt atcacgcgat gagatggggc ttcccaagga
    12001 cgatattgag gagaccggca ccacttttga agaaaactca tatatcaaag cctctacaat
    12061 cgccaagcag tgcgacggaa tagtagttgc agatgatagc ggaattgccg tcgactgcat
    12121 cggcggaaat ccgggagtgt attccgcaag atttgcagga gaaggttgca ctcctcacga
    12181 taataacgta aagttacttc agctgatgga tggaatccct gcagatgaga gaggcgctaa
    12241 atttgtctcc gtcatcacac tcatctaccc ggacggcaag aagctcgtgg ctcgaggtga
    12301 gtgtgagggc tctattgctg aggaaatacg tggagaccat ggctttggct atgatccgtt
    12361 attcatccct aaaggttatg ataagacttt tggagagctt tctgttgagc tcaagaacaa
    12421 gataagccac agagctaagt ctcttcacaa gctagaggaa ttaattcgtg agcaaagaga
    12481 taaataatgc ttcaaattta aatacggaga atattggaga gggtgagaat gaaaaggtcc
    12541 gtcttaccaa ggacaatctg gttagaatcg gctttcacat ttttcggcag tttgacgacc
    12601 agtattatgc cggcttcgct gcgcagattg catatttctt tttcatggcc agcgttccga
    12661 cgctcatcgt gctgtcgcag ctgctgggcg tctttgattt gtctctggat atcatcaaaa
    12721 actggctgga ccacaatgtc gattctacgt tgagcagctt cgtcatggga ctgttttcgg
    12781 cttcttcggt cagactcggc aactttgtgc tgattttcct ggcactttgg gcggcttcgg
    12841 ccttggaatt ctcgctttcc agattgacca gttatacgtt aaccgacggt gcatataaat
    12901 tcaacttttt caaggagagg attaaagcgg ttccgacggc agctcttacg atatttgccg
    12961 tcgcttttac acttgtcgta tttgtatacg gtgaagagat attctccaag ctgttcaaag
    13021 gcagcatctt ttcgcaggtg ttgctcggac ttagactacc aatcgtagcc gggtcatttt
    13081 tcgctatgat tacgctgaat tattatatct taccgctcgt gagggttccg ctgcgtgcga
    13141 tactgcccgg agccgtattc tcttcactcg gaattctgat cgcgacgagc atttacgcgt
    13201 attatatcgg atatgctacc aattacgata tcctgtatgg cgcattctca tccattgtcg
    13261 ctctgatgct gtggttctat attatttcat ggattctctg cataggtatg atgtttaaca
    13321 aggcttggga tgaagtcatg gaacgcgaca ggctcagtca cgacaggatg atcgagtata
    13381 ttgaaaaaca gtctaatttg ttaggtgaag atctatataa gaaatacttt attacgggag
    13441 atgacgacta cggtaccgag actcttgcag ttaagatgag ccgcaaattc gtcaagggtt
    13501 acgaggaaga gctccgtaag gagaaacaga agaaggcacg ccgccatcta tagcgaggga
    13561 atacatgaaa gaaactaacg taaatagcga aagaattgat aggaaaaagc ttgtatttat
    13621 cttaaatccg cgtgcaggca ctatgcaggc caataagtat atggtagata ttcttcagac
    13681 cttttctgat gccggattca taacaagtgt gctgattact gcgaagtccg gagatgcgcg
    13741 tgagtttgct gtccggtacg cgaatgactg tgatgtcatg gcctgtgccg gaggagacgg
    13801 aacattcaac gagatgatcg atggtgttat ttcatccggg gctaagtgca ggataggtta
    13861 tataccggca ggaagtacca acgatttcgg tgcgagcatc ggtctgtcca aaaacatcat
    13921 tgaggctgca aattccattg caaacggcga ggctattacg cttgatgttg gttcgtttaa
    13981 cggacgattc ttctcgtatg tcgcttcctt cggagcattt acgagtacgg catattcagt
    14041 gccgcagaac ctcaaaaata ttctgggaca taccgcatat gtaatgcaag ggatcaagga
    14101 tatcgtcaat atcaagtcac atcatgtcaa agtcatcacc gatgaaggca tggcaagtga
    14161 gagagttatc gaggaaaatt tgatctttgg tgcagtatgt aattcgactt cagtcggagg
    14221 tatgattaag ctcgactcct tcaaggttga catgaatgat ggcttgatgg agatcttgct
    14281 gatcaagtca cccaggaacc tgctggatct gaattctatt gccagatcta ttctggcaaa
    14341 cgatctggac actaaagaca ttgcctttta cagtgccaag acggtaaggt ttgagatgag
    14401 cgaagctatt ccttggacct tggatgggga gtatgagccc ggcgcaagtg taatcaatat
    14461 cgataccgtt tgcgatgcta tcgatatact cgtttagcat acattggcgg ggatagcgag
    14521 tttagtccgg cgcagcaatt atcaagtaac gcttaaaaac atacttgata ttcaatcaaa
    14581 taagagaaat cagaaatccg gcaatgatgc ttcgcatcct gccggattat gtcatatgtt
    14641 taatgatacg ccatctcggt gtttcgctgc tttgcaaata tagaaattca accgagctat
    14701 gtcgatcaaa ccataggcgc agcttatacc ttatagctcg cgaaccttta ggatgccctc
    14761 gcctgcaagc tcaccggctg catcagcagc aacgagagcg attgcagcac cgtattcagt
    14821 gcggctcctg ccaacgcata catccgcaac atctccgtaa gcagccttga tagcagcctc
    14881 gatatcgatc tcgcccttgt acagaacgca tacctttttg aagccggcct tacctgcaag
    14941 ctcaacgcct gggaagttaa cagagttctt gatggttcct tcctcgaggt aagccataag
    15001 ctcatcaaca gccatagaag cacagttttc ttcagcctct gctgtggaag ctccgaggtg
    15061 tggtgtggtg attacgccgg ccttacctac aagctcctcg ttaggaacat ctgtgaggta
    15121 ctttctgatc ttaccggatt caattccagc cagaatatct gcgtttacgg ccagatcagg
    15181 tctggcaaag ttgagaatga ttactccttc cttcatgttg gcgatgagat ccttattgat
    15241 catgccctta gtctccggaa gtgaaggaac gtggatagaa atgtagtcgc aaactttaac
    15301 catttcagct acatcatcat acatctcgca tggagcactg agaataggat gaacgactac
    15361 agaattacca acgatgttca taccgagtgc gtgtgctgcg tttgcaacct ttgcaccgat
    15421 tgcaccgagg ccgataattc cgagtgtctt gccggaaatc tctgtaccgg cgaactgttt
    15481 tttgcccttt tcaacctgtc cggcaacatc gccctcgagg gtatttgccc aagcgactcc
    15541 ctcgtacata tttctagctc ccatgatcat tgctgagata accagctcct taaccgcgtt
    15601 ggaattcgct ccgggtgcgt tgaatacaac gatgccgtcc tctgcacatc tgtccagagg
    15661 aatgttgttg acgccggcgc cggctcttcc tatagccata aggttgtcgg agaaatccat
    15721 ctcgtgcatc ttgtagctgc gaacaacgat cccgtttgcc ttgtctatat cttctgtcaa
    15781 ctcatactta tcagtgagtc tgccgagccc tgcctcggag atgttgttga gcgtaccgat
    15841 ataaaatttg tccattctta agtacctcct cttgccaccc gttcgggaac ggtgtggtca
    15901 taatgctgaa aaacaaatca atctcaatag ttcatttatc gtgcacagtt acggcgtgaa
    15961 cagtgccgca agtgttgaaa aatgcgctat ttacgtaatc aagtatagca ttattattct
    16021 ttacattcaa tgttgaaagt gctacaattc tcgtgtaagt ttgaaacaaa tttggaggta
    16081 tttagatggc tacaaatgaa cgcgtattca acttttctgc aggtccttcg actctccctg
    16141 ttgaggtact ggaaaaggct gctgctgaga tgttgaacta tgagggaacc ggtgagtctg
    16201 taatggagat gagccacaga tccgcagaat tccagcagat tatcgacgat gctgagaaga
    16261 atctgagaga gcttatgaac attcctgatg attattatgt tctgttcctt cagggtggtg
    16321 gaactctaca gttctcgatg gtaccgatta acctgatgac aggaagaggg aaggctgatt
    16381 accttgtaac cggcaactgg gctaagaagg cttatgaaga ggctactaag tttggtgatg
    16441 ttaaggttgt tgcaagctct gaggatgatc tgtattcata catccctaag attacacctg
    16501 aggatatcag acccgatgta gactacgtat acgtatgcta caacaacact atttacggaa
    16561 cacactgcaa cgagattcct aacgtaggag atcacatgct tgttgcggat atgtcttcgt
    16621 gcattttatc tgaagagatt gatgtaacca aattcggtct catctatgca ggtgctcaga
    16681 agaatgttgc tccggctggt gttacaatcg ttatagtaag aaaggatatc gtaggacacg
    16741 ctccagcgaa tactccgatc tatctcgatt atgcaacaca cgctaagaag ggttcgatgt
    16801 acaacactcc accttgctat ccaatctatg tagcaggcga ggtgtttaag tatcttctta
    16861 gaaatggcgg tgtcaaggca actcacgaga gagacgttga gaaggcaaag attctctatg
    16921 attatctcga caagagcaag atgttcaagc cgtccgttgc taaggaggac agatcgctaa
    16981 tgaatatcac gtttgtaacc ggcgatgcag acctcgacaa aaagttcatt gccggcgcaa
    17041 gggaggcggg tatgatcaac cttgcaggtc acagatctgt cggcggaatg agagcaagca
    17101 tatataacgc aatgcctaag gaaggcgttg agactctcgt tgcttacatg gaaaagtttg
    17161 agaatgagaa caaataacag gattattaat tcaaaaaata ttaataaaag tcttgtgaga
    17221 attatggtgg ccgtcttggc gatgattttg gtgtcgtcat tgatggtcac catcaatatt
    17281 aatacaagct ttgcagcatc taagaaaaag gcaaaagcca agacgagcga tgttactgct
    17341 ccggagatac aggcgcagtc ggcggtcgtc ttttcggcgt ctacaaatga ggtggtattt
    17401 tcatctcata gagatagaaa gcttccaccg gggagcacag tgcagctgat ggtggctatg
    17461 gtagtcatcg ataatatgca cgatgataag gaatataaga acagcgtcca gataactgaa
    17521 gatatgcaca gcgccggcac gacttatccc gtgggttcga gcgtcaaggt agaggatttg
    17581 atgtacacga tgctcatgtc gggagatgcg gagtccgcca aggcattggc cacatattct
    17641 gcaggaactg agtcgaattt tgtcgaccag atgaattcca aggctcaaca gctggggctc
    17701 gtcaatacca gatatacaaa ttcaaccggt gcgtataata cggaccagtt ttccacagct
    17761 gaagatactg ccaagattgc gaaagctgca taccagtacg gtgtgattaa gcagatgtcc
    17821 ggcgaagatc gtcactcggt aaaggtcaca gacggtaacg gggataaaac tattgaaaat
    17881 actcatccgt tcatgtccgg cagctcttcc tataagggct ttaagggagg aagctattcg
    17941 aagctaagcg aaccggattc taaggaggtt ttccttgcca gtgccattag gaacgatatg
    18001 aacctgattg tcgtgttgtt tgatgaagct ccgggtaaat cgactacaga tgcgaccaaa
    18061 cttctcgact atgggttcca aaaggcaact caaaaggtga taatcaaaaa ggatgtcaag
    18121 atcggtaagg tcaggattaa gcacggtgca aagaccagac tggcggcgta tacctcgggc
    18181 aagggctacg tatatattcc gccggagggc agtgattctc ttgtaaagac ggaatcggtt
    18241 attttcgaca acgtggaagc tccgctaaag gcaggagaca aggtcggtga atacaggata
    18301 tacgtggctg atgagctaac cggtactgtt gatctcgtcg tcaaggaaga tgtcagcctt
    18361 gggtggcttc catcgtatat atacatttca aatatgatga ctgtcataat ctgcgtaatt
    18421 ctgctgataa ttgtgttgct gattgttcgc gccgggaata taaaacgtcg tagaaagcac
    18481 atgagagcga gaaagcacaa ggagaagatt cgcgagattg cccggcagcg tctggagatt
    18541 gaggaagaca gaaaaaggcg taactggaat tacaaataga ctatgtatat actggagatt
    18601 ttagaaatat cgagcaatgt ttaacatcga agaggaactg aaaaagcttc cgctttcacc
    18661 gggagtctat atgcataagg atagccttgg taacgtaatt tacgttggca aggctattaa
    18721 gttaaggaat agggtttcgc aatattttca caaaaattcg cagcacactc caaaggtgct
    18781 ggcgatggtc gagaatattg cggagtttga ttatatcacg tgcgccacgg agatggaggc
    18841 actcatcttg gagtgcaatc tcatcaagaa atacatgcct aagtataaca tcctgcttaa
    18901 ggacggcaag acgtatccgt acattgaggt tacggtaagc gaagagttcc cgcgtgtagt
    18961 cagaacccga gaggtgaaga gagacggcaa caaatatttc ggaccgtatt cggatagcgg
    19021 agcggtaagc aggataatta agctgattga cgagatttat cccgtcaaga agtgcaagac
    19081 caaggagttc cctgcaaatg tccgtccgtg cctaaactac tatatcggta agtgcaaagg
    19141 tatctgcatt aatgccgcag acaaatccga gtatgatgag atgatagaga gcatactcaa
    19201 gattttgaat ggcaaggatg caaagctgat aaaagacttg aaggggaaaa tgctggaggc
    19261 atccgataag cttgaatatg aagaggcggc aaagtacaga gattacataa atgcttttaa
    19321 ggcgcttggc gagacacagc gtgccactat ggcgagtgat agggatgtgg atgtcctgct
    19381 gccgcttgct gctcagaata gtcagatagt tgcgcaatac aaggtgagag aggggaagct
    19441 cctcggcagg gaaatacact atatggatga ggcggatccg gagctcgggg gctccgggaa
    19501 tgaattgatt gaggcgttta tcaagcagta ctatacggga agtgcaaagc tgccaaagga
    19561 aattttgctg accgagcata ttgatgaaga ggaccttgtc aagggacttc tcgataacac
    19621 caacgccgaa aatgccaagg caaagagtga tacggcacac cgtaccaaga ttacagttcc
    19681 tgagcgcggc gagaaaaagg ctattctcga tctcgcaatc agcgactctc tgcaggttgt
    19741 caaagggctt gatgaaagag ctgaacggga cgcggagaag agggacaatc tgagaaatga
    19801 gataaccaag cttattaagc gcgcgtcaga tattgaaggc tctgtcccat acataataga
    19861 agatggagat gatagagagt atcgcatcga agcgtatgat atatccaaca tgaatgggct
    19921 tgatactgta ggagcaatgg tcgtgtatga gggagcaaag cctgtcagga atgattacag
    19981 gaaattcaag ataaagagtg ccgacgcaga gggtgatgac tacgcttcac tgcaggaggt
    20041 catatatagg aggctgaagc gagctaagga taacgatgcg gggttcaaca ggtatccgga
    20101 catatttttc atagatggag gcctcggaca ggtgcatgcg gtacaaaatg ttgtcgctgc
    20161 atttcgtatg tcgataccgg ttgtcggtct tgcgaaggat gacgtacaca gaactagagc
    20221 gattatattc ggtgatggaa ctgagattga gctcagggac gagccgatgc tgtatagcta
    20281 ttgcggcaga atacaggaag aggtgcatag gtttgcaata accttccagc ggggcagacg
    20341 gacatcgaag atgacaaagt ctgcgcttga ggaaataccg gggatcggtc ctgccagacg
    20401 aaaagaattg ctcagacatt ttaaaaatat cgaatcgatt aagcgcgcaa gctacgatga
    20461 gctgctggag tgcgattcca tcagcagtaa ggcggctgaa aacattcttg aatactttgg
    20521 caagaaatag cggaaataca ttgataaatg aacataataa tgttatatta acctcacagt
    20581 gatagagaaa aggagagtaa ccatgtctca ggaagaacgc aacatgattg aagaggaaga
    20641 ggatattatc actcttgagt ttgatgacgg aactgcagtt gattgtgatg ttttaggaac
    20701 attcgaggcc gattcgaagg agtatatagc acttgcacca atcgacggta cagacgacgt
    20761 gtacatctac ggctacaagg atatagatcc tgaaacattt gatatcgttg acatcgatga
    20821 cgaggatgaa ttcaacaacg cagtaaaggc tttcgaagca gcaatgtctg aggtagatga
    20881 atagtatatg ctgctataga ttagatattg tttaccgcgc tgagtgcttc ggcgcggttt
    20941 tactgtgatt atttaatgtt tacaaggtgc ggatattatt gtataatgtc acctgtctat
    21001 ttgaattatt gattaaatga gcggatgtgg cggaattggc agacgcgcac ggttcaggtc
    21061 cgtgtgacca ccagtcatga gggttcgagt ccctccatcc gcaccaggct acccttgctc
    21121 aggcaagggt tcttttttca aggagaagga tatggacaac agagctatag ggttctttga
    21181 ttcgggatta ggcggactga ctagcatacc tgttctcaag aaaactcttc caaatgaaaa
    21241 agtcttgtat tttggagata ctgcgaggac accatacgga tccaagtcgc cggaaactgt
    21301 gcgcaagttc tccgcgcaga ttgtagacta tctggttagc aaaaatgtaa agttgattgt
    21361 gatagcctgc aacactgtta ctgctatggc gctagacatg ctgagggatc tgcatccgga
    21421 tgttccgata gttggagtaa tagagccgac ggccaggcac gttgcagctg acggagtaga
    21481 taatgtcggt atcatcggaa ccaaggtcac gattgggagc ggagtatatg ccgagaggat
    21541 tcatgaactt aatcccggca tcagaacaca tagcctggcg tgtccggcgc ttgtaccgtt
    21601 gattgaagat gggattattg acaacgagat tatggatctc acggtcaggt actatatgga
    21661 tgactt
//
