LOCUS       c00068_NZ_FNHQ..       12717 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FNHQ01000042.1 Megasphaera paucivorans strain DSM 16981, whole
            genome shotgun sequence.
ACCESSION   NZ_FNHQ01000042
VERSION     NZ_FNHQ01000042
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:07:21
            Original ID  :: NZ_FNHQ01000042.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 6749
            Orig. end    :: 19466
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12717
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[16749:18343]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11594
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12717
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12717
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             223..1716
                     /locus_tag="ctg68_6"
                     /transl_table=11
                     /translation="MMYNVPNHNLEASLLYTNALLTDLYQLTMMQGLFFEGKHNQPCVF
                     DRYYRTNPFKGGYTVVAGLEHLIDYVQNMHFSDDDIYYLKSTNLFKESFLDYLKDMHFT
                     GDIYAMPEGTVAFPQEVLLRIHTTKDESLLLETAMSMIMNHESLIATKARRVRTVAGND
                     TLMEFGLRRAQGMSAGVYGARSAMIGGFNGTSNVLSGAKFGMPILGTMAHSWIMSFPSE
                     LEAFHAYIRQYPNNLILLADTYNTLKQGVPDAITVFQEMKDAGTLPKKFGIRLDSGDLA
                     YLSKEAKKMFDAAGFPDVIISASNDLDEFLISELKLQGCAINSWGVGTHLITAEDSPSL
                     GGVFKLVGQYDGDVFVPKIKMSDNAEKISNPGIKNVYRIYDRESKKMKADIIALEGEKF
                     PTIKNLQLVSDKTPWRSRVIYANSFDVCPMLQPIFQKGKLVYHKPTLAAICDYADEQIQ
                     TLWPEYLRLVNPEEMWVQRSSKLSKLRNKILQEESAKFM"
     aSDomain        277..1662
                     /aSDomain="TIGR01513"
                     /aSTool="tigrfam"
                     /description="NAPRTase_put: nicotinate
                     phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_6_0001"
                     /evalue="6.90E-160"
                     /identifier="TIGR01513"
                     /label="ctg68_6"
                     /locus_tag="ctg68_6"
                     /protein_end="480"
                     /protein_start="18"
                     /score="530.8"
                     /tool="antismash"
                     /translation="ALLTDLYQLTMMQGLFFEGKHNQPCVFDRYYRTNPFKGGYTVVAG
                     LEHLIDYVQNMHFSDDDIYYLKSTNLFKESFLDYLKDMHFTGDIYAMPEGTVAFPQEVL
                     LRIHTTKDESLLLETAMSMIMNHESLIATKARRVRTVAGNDTLMEFGLRRAQGMSAGVY
                     GARSAMIGGFNGTSNVLSGAKFGMPILGTMAHSWIMSFPSELEAFHAYIRQYPNNLILL
                     ADTYNTLKQGVPDAITVFQEMKDAGTLPKKFGIRLDSGDLAYLSKEAKKMFDAAGFPDV
                     IISASNDLDEFLISELKLQGCAINSWGVGTHLITAEDSPSLGGVFKLVGQYDGDVFVPK
                     IKMSDNAEKISNPGIKNVYRIYDRESKKMKADIIALEGEKFPTIKNLQLVSDKTPWRSR
                     VIYANSFDVCPMLQPIFQKGKLVYHKPTLAAICDYADEQIQTLWPEYLRLVNPEEMWVQ
                     RSSK"
     PFAM_domain     280..654
                     /aSDomain="NAPRTase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17767.3"
                     /description="Nicotinate phosphoribosyltransferase
                     (NAPRTase) N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_6_0001"
                     /evalue="9.10E-35"
                     /label="ctg68_6"
                     /locus_tag="ctg68_6"
                     /protein_end="144"
                     /protein_start="19"
                     /score="119.7"
                     /tool="antismash"
                     /translation="LLTDLYQLTMMQGLFFEGKHNQPCVFDRYYRTNPFKGGYTVVAGL
                     EHLIDYVQNMHFSDDDIYYLKSTNLFKESFLDYLKDMHFTGDIYAMPEGTVAFPQEVLL
                     RIHTTKDESLLLETAMSMIMN"
     PFAM_domain     715..1095
                     /aSDomain="NAPRTase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04095.18"
                     /description="Nicotinate phosphoribosyltransferase
                     (NAPRTase) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_6_0002"
                     /evalue="6.60E-10"
                     /label="ctg68_6"
                     /locus_tag="ctg68_6"
                     /protein_end="291"
                     /protein_start="164"
                     /score="39.0"
                     /tool="antismash"
                     /translation="LMEFGLRRAQGMSAGVYGARSAMIGGFNGTSNVLSGAKFGMPILG
                     TMAHSWIMSFPSELEAFHAYIRQYPNNLILLADTYNTLKQGVPDAITVFQEMKDAGTLP
                     KKFGIRLDSGDLAYLSKEAKKMF"
     PFAM_domain     1342..1674
                     /aSDomain="NAPRTase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17956.3"
                     /description="Nicotinate phosphoribosyltransferase
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_6_0003"
                     /evalue="8.00E-25"
                     /label="ctg68_6"
                     /locus_tag="ctg68_6"
                     /protein_end="484"
                     /protein_start="373"
                     /score="87.5"
                     /tool="antismash"
                     /translation="KNVYRIYDRESKKMKADIIALEGEKFPTIKNLQLVSDKTPWRSRV
                     IYANSFDVCPMLQPIFQKGKLVYHKPTLAAICDYADEQIQTLWPEYLRLVNPEEMWVQR
                     SSKLSKL"
     CDS             1862..2671
                     /locus_tag="ctg68_7"
                     /transl_table=11
                     /translation="MRGAILGDIAGSLYEARSYRIKTKEFPLFSKNSRFTDDTVTTVAV
                     ADALIEAYREKKGLSIPLRKKMQYWCRKYPDAGYGPYFKKWFQTEAAKPYGSYGNGAAM
                     RVSPVAWVGKSLPEVQYLAELTAVVTHDTQEAITGAVAVASAIYLARIKKNKDSIRSYI
                     QQYYYPMEQSLDTIRLNYQFTSRTQESVPQGIEAFLESENVEDSIRNAISLGGDSDTQA
                     AIAASIAEAYYGGVPHTVWQDALQRLTPELKEVLSIFEHIFKSQYSF"
     PFAM_domain     1868..2563
                     /aSDomain="ADP_ribosyl_GH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03747.16"
                     /description="ADP-ribosylglycohydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_7_0004"
                     /evalue="1.50E-25"
                     /label="ctg68_7"
                     /locus_tag="ctg68_7"
                     /protein_end="234"
                     /protein_start="2"
                     /score="90.6"
                     /tool="antismash"
                     /translation="GAILGDIAGSLYEARSYRIKTKEFPLFSKNSRFTDDTVTTVAVAD
                     ALIEAYREKKGLSIPLRKKMQYWCRKYPDAGYGPYFKKWFQTEAAKPYGSYGNGAAMRV
                     SPVAWVGKSLPEVQYLAELTAVVTHDTQEAITGAVAVASAIYLARIKKNKDSIRSYIQQ
                     YYYPMEQSLDTIRLNYQFTSRTQESVPQGIEAFLESENVEDSIRNAISLGGDSDTQAAI
                     AASIAEAYYG"
     CDS             2693..3820
                     /locus_tag="ctg68_8"
                     /transl_table=11
                     /translation="VIKEKSFSVLYRITANSKEEAQNLAQKIAVEQTIEFPPDLVERQS
                     IFDNIVGNIEFAEYGDGQYRYWITYNDGAAGTEITQLFNVVFGNSSMQPGIWVEDVTFS
                     SAFLSEYHGPHFGIAGIRKLLGVFHRPLLHCVIKPLGSTTAELARMAYEFAAGGADLIK
                     DDHGITNQASAPFAERVAACADAVQKANEDTGGHAVYVANCTADGTKSHERALQAKKLG
                     AGGILLAPVLTGFGMIREIADDPLVGLPIISHPSLSGGFIMPGPSGVVMSVLYGIFSRL
                     AGADAVVFPSYGGRFTFTAEDCRKIAESARKHLGELAAIFPSPGGGITEETIPKLAQLY
                     GRDVIYLVGGGIFRHGPDLLENTKFYKMMIQEIYS"
     PFAM_domain     3041..3757
                     /aSDomain="RuBisCO_large"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00016.22"
                     /description="Ribulose bisphosphate carboxylase large
                     chain, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_8_0005"
                     /evalue="6.20E-29"
                     /label="ctg68_8"
                     /locus_tag="ctg68_8"
                     /protein_end="355"
                     /protein_start="116"
                     /score="101.2"
                     /tool="antismash"
                     /translation="GIAGIRKLLGVFHRPLLHCVIKPLGSTTAELARMAYEFAAGGADL
                     IKDDHGITNQASAPFAERVAACADAVQKANEDTGGHAVYVANCTADGTKSHERALQAKK
                     LGAGGILLAPVLTGFGMIREIADDPLVGLPIISHPSLSGGFIMPGPSGVVMSVLYGIFS
                     RLAGADAVVFPSYGGRFTFTAEDCRKIAESARKHLGELAAIFPSPGGGITEETIPKLAQ
                     LYGRDVIYLVGGGIFRH"
     CDS             3817..4635
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="VNTEQKYEKLKEILKDMGSVVIGFSGGVDSTLLSYTAYTVLGEQA
                     LAVTAVSPTLPASERSDAESLAKVIGIPHREVLSTEFDNPDFVRNPKERCYICKKIRFE
                     ALVKLAQSEGYHWVIDGGNIDDLDDYRPGMKALQELSDHVRSPMIEAGLGKADIRIISR
                     TLGLRTWDKQSAACLASRIPYGMELTPERLEQIDKAETYIAPFIHGSLRVRYHGDIARI
                     EVGMEELNVILKHRQSIVKALKKCGFTYVTLDLGGYEMGSLNEGISVKEE"
     aSDomain        3832..4599
                     /aSDomain="TIGR00268"
                     /aSTool="tigrfam"
                     /description="TIGR00268: TIGR00268 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_9_0002"
                     /evalue="8.50E-77"
                     /identifier="TIGR00268"
                     /label="ctg68_9"
                     /locus_tag="ctg68_9"
                     /protein_end="261"
                     /protein_start="5"
                     /score="256.1"
                     /tool="antismash"
                     /translation="KYEKLKEILKDMGSVVIGFSGGVDSTLLSYTAYTVLGEQALAVTA
                     VSPTLPASERSDAESLAKVIGIPHREVLSTEFDNPDFVRNPKERCYICKKIRFEALVKL
                     AQSEGYHWVIDGGNIDDLDDYRPGMKALQELSDHVRSPMIEAGLGKADIRIISRTLGLR
                     TWDKQSAACLASRIPYGMELTPERLEQIDKAETYIAPFIHGSLRVRYHGDIARIEVGME
                     ELNVILKHRQSIVKALKKCGFTYVTLDLGGYEMG"
     PFAM_domain     3859..4044
                     /aSDomain="NAD_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02540.19"
                     /description="NAD synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_9_0006"
                     /evalue="2.10E-06"
                     /label="ctg68_9"
                     /locus_tag="ctg68_9"
                     /protein_end="76"
                     /protein_start="14"
                     /score="27.1"
                     /tool="antismash"
                     /translation="KDMGSVVIGFSGGVDSTLLSYTAYTVLGEQALAVTAVSPTLPASE
                     RSDAESLAKVIGIPHRE"
     CDS             4642..5283
                     /locus_tag="ctg68_10"
                     /transl_table=11
                     /translation="MAITKKIKQEMLERFQQQYGILKPALHYHSPFELLVAVVLSAQCT
                     DERVNIVTEDLFPLYNTPKKMLELGLLGLESKIRTCGLYHSKAQHLLETSVILCEKYDG
                     EVPQSFEELVKLPGVGRKTANVLVSILFNIPAIAVDTHVFRVANRTELAVGKTPLDVEL
                     GLQKAIPKKWWSRAHHWLIWHGRRICKARTPLCDDCILNDLCPAAALKDS"
     aSDomain        4657..5229
                     /aSDomain="TIGR01083"
                     /aSTool="tigrfam"
                     /description="nth: endonuclease III"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_10_0003"
                     /evalue="5.60E-77"
                     /identifier="TIGR01083"
                     /label="ctg68_10"
                     /locus_tag="ctg68_10"
                     /protein_end="196"
                     /protein_start="5"
                     /score="255.7"
                     /tool="antismash"
                     /translation="KIKQEMLERFQQQYGILKPALHYHSPFELLVAVVLSAQCTDERVN
                     IVTEDLFPLYNTPKKMLELGLLGLESKIRTCGLYHSKAQHLLETSVILCEKYDGEVPQS
                     FEELVKLPGVGRKTANVLVSILFNIPAIAVDTHVFRVANRTELAVGKTPLDVELGLQKA
                     IPKKWWSRAHHWLIWHGRRICKARTPLC"
     PFAM_domain     4747..5151
                     /aSDomain="HhH-GPD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00730.27"
                     /description="HhH-GPD superfamily base excision DNA repair
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_10_0007"
                     /evalue="1.70E-17"
                     /label="ctg68_10"
                     /locus_tag="ctg68_10"
                     /protein_end="170"
                     /protein_start="35"
                     /score="63.8"
                     /tool="antismash"
                     /translation="VAVVLSAQCTDERVNIVTEDLFPLYNTPKKMLELGLLGLESKIRT
                     CGLYHSKAQHLLETSVILCEKYDGEVPQSFEELVKLPGVGRKTANVLVSILFNIPAIAV
                     DTHVFRVANRTELAVGKTPLDVELGLQKAIP"
     PFAM_domain     5206..5256
                     /aSDomain="EndIII_4Fe-2S"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10576.11"
                     /description="Iron-sulfur binding domain of endonuclease
                     III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_10_0008"
                     /evalue="1.80E-04"
                     /label="ctg68_10"
                     /locus_tag="ctg68_10"
                     /protein_end="205"
                     /protein_start="188"
                     /score="21.8"
                     /tool="antismash"
                     /translation="CKARTPLCDDCILNDLC"
     CDS             complement(5489..6835)
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MNEKKGNAIALLPLVVFMALFLGVSLIMKDFYKMPVVVALLIAST
                     IAILQNKTIPIDLKVERFCKGAGDSSIILMCLIFILAGAFAEVSKAMGAVDATVNLGLT
                     IFPPSLMVAGMFVIGSFLSMSLGTSVGTIVTLAPIAVGIAEKTGLPVGFLIAAVVSGAM
                     FGDGLSMISNSTVAATKTQDVEMVDKFKANFKIVLPAAIITLIIYACLTLGMDVNATET
                     YDYQFFKILPYIAVLTVALTGLNVVLVLVGGIILSAVIGMIYGSFDIFTVFQLCLKGIS
                     GMEDISIISILIGGMGELTKINGGIDFLLHTIQKKIHSEKGAELGIGILVSLVDLCTAN
                     NTVSIIIVGSLAKDLSEKYGVDRRKTASLLDTFACFIQGCIPYGAQLLVASSLAAISPF
                     SIMGYLCYPYLLGISSILAIVLGIPKFKTPIKDTTLCASQPMTPDMTEK"
     PFAM_domain     complement(5567..6130)
                     /aSDomain="Na_H_antiporter"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03553.16"
                     /description="Na+/H+ antiporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_11_0010"
                     /evalue="6.20E-15"
                     /label="ctg68_11"
                     /locus_tag="ctg68_11"
                     /protein_end="423"
                     /protein_start="235"
                     /score="55.3"
                     /tool="antismash"
                     /translation="VLTVALTGLNVVLVLVGGIILSAVIGMIYGSFDIFTVFQLCLKGI
                     SGMEDISIISILIGGMGELTKINGGIDFLLHTIQKKIHSEKGAELGIGILVSLVDLCTA
                     NNTVSIIIVGSLAKDLSEKYGVDRRKTASLLDTFACFIQGCIPYGAQLLVASSLAAISP
                     FSIMGYLCYPYLLGISSILAIVLGI"
     PFAM_domain     complement(6206..6631)
                     /aSDomain="Na_H_antiporter"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03553.16"
                     /description="Na+/H+ antiporter family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_11_0009"
                     /evalue="6.40E-14"
                     /label="ctg68_11"
                     /locus_tag="ctg68_11"
                     /protein_end="210"
                     /protein_start="68"
                     /score="52.0"
                     /tool="antismash"
                     /translation="DSSIILMCLIFILAGAFAEVSKAMGAVDATVNLGLTIFPPSLMVA
                     GMFVIGSFLSMSLGTSVGTIVTLAPIAVGIAEKTGLPVGFLIAAVVSGAMFGDGLSMIS
                     NSTVAATKTQDVEMVDKFKANFKIVLPAAIITLIIYAC"
     CDS             7064..7711
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 130.8; E-value: 9.9e-40)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MTFQQLKYIIEISKSRSITAAAQNLFISQPSLSKSVKELETELGI
                     TILKRTRHGISFTSSGMEFLSYAYRIAEQIEGMQSYFRQDETNERKINLSISAQHYMFP
                     TDALVQFIQKAEKYHSYTVTMQEGRTTQVIHDVLVQQSQIGIIYVSKATEKFMHRLFQH
                     KGLEFIPFRQYPPYVYLRAQHPLASRKQINVRELEPYPYVRYGQGQDPYLFF"
     PFAM_domain     7070..7246
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_12_0011"
                     /evalue="8.90E-17"
                     /label="ctg68_12"
                     /locus_tag="ctg68_12"
                     /protein_end="61"
                     /protein_start="2"
                     /score="60.9"
                     /tool="antismash"
                     /translation="FQQLKYIIEISKSRSITAAAQNLFISQPSLSKSVKELETELGITI
                     LKRTRHGISFTSSG"
     CDS             7668..8012
                     /locus_tag="ctg68_13"
                     /transl_table=11
                     /translation="MYDTDKDRTRIFFSEEVIIPDMSNKKLIYVTDRSSLLSMLRNTNS
                     FNIGTGCLLPDIVGDAIISIPVEDCIDMMEIGWLKLKNMKMTQEMTLYVQLLEDSLNRC
                     TCGSIATEQS"
     CDS             8109..9308
                     /NRPS_PKS="Domain: Aminotran_5 (88-235). E-value: 1.3e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg68_14_Aminotran_5.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168:O-succinylhomoserine sulfhydrylase (Score: 465.3;
                     E-value: 2.1e-141)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_14"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-08,
                     bitscore: 25.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKQLQAMGFATKAIHGGTSKNTFGALTCPIYQTSTFVFDSAEQ
                     GGRRFALEEGGYIYSRLGNPTNTVIEEKLALLEEAEGCVATASGMGAISAALWTALHAG
                     DHVVASDTLYGCTFALLNHGMTRYGVEVTFVDMADLDAVKKAMKPNTRVVYLETPANPT
                     LKITDIHAVSEIAHSVEECIVIVDNTFCTPYIQRPLLLGADVVVHSATKYLNGHGDVIA
                     GFVCGKQEYINNVRFFGLKDMTGAVLSPFDAFLIARGMKTLAIRMDRHCSNAMKVAQFL
                     ETHPAVASVSYPGLKSFPYYELAQKQMRLPGGMLSFELKGGVKEGAVVMNNVKLCKLAV
                     SLGDAETLIEHAASMTHSTYTKEELASAGISEGLVRLSVGLEDPEDIIFDLKQALDLII
                     "
     aSDomain        8133..9296
                     /aSDomain="TIGR01328"
                     /aSTool="tigrfam"
                     /description="met_gam_lyase: methionine gamma-lyase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_14_0004"
                     /evalue="6.20E-183"
                     /identifier="TIGR01328"
                     /label="ctg68_14"
                     /locus_tag="ctg68_14"
                     /protein_end="396"
                     /protein_start="8"
                     /score="606.0"
                     /tool="antismash"
                     /translation="MGFATKAIHGGTSKNTFGALTCPIYQTSTFVFDSAEQGGRRFALE
                     EGGYIYSRLGNPTNTVIEEKLALLEEAEGCVATASGMGAISAALWTALHAGDHVVASDT
                     LYGCTFALLNHGMTRYGVEVTFVDMADLDAVKKAMKPNTRVVYLETPANPTLKITDIHA
                     VSEIAHSVEECIVIVDNTFCTPYIQRPLLLGADVVVHSATKYLNGHGDVIAGFVCGKQE
                     YINNVRFFGLKDMTGAVLSPFDAFLIARGMKTLAIRMDRHCSNAMKVAQFLETHPAVAS
                     VSYPGLKSFPYYELAQKQMRLPGGMLSFELKGGVKEGAVVMNNVKLCKLAVSLGDAETL
                     IEHAASMTHSTYTKEELASAGISEGLVRLSVGLEDPEDIIFDLKQALD"
     PFAM_domain     8145..9293
                     /aSDomain="Cys_Met_Meta_PP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01053.22"
                     /description="Cys/Met metabolism PLP-dependent enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_14_0012"
                     /evalue="9.20E-152"
                     /label="ctg68_14"
                     /locus_tag="ctg68_14"
                     /protein_end="395"
                     /protein_start="12"
                     /score="505.1"
                     /tool="antismash"
                     /translation="TKAIHGGTSKNTFGALTCPIYQTSTFVFDSAEQGGRRFALEEGGY
                     IYSRLGNPTNTVIEEKLALLEEAEGCVATASGMGAISAALWTALHAGDHVVASDTLYGC
                     TFALLNHGMTRYGVEVTFVDMADLDAVKKAMKPNTRVVYLETPANPTLKITDIHAVSEI
                     AHSVEECIVIVDNTFCTPYIQRPLLLGADVVVHSATKYLNGHGDVIAGFVCGKQEYINN
                     VRFFGLKDMTGAVLSPFDAFLIARGMKTLAIRMDRHCSNAMKVAQFLETHPAVASVSYP
                     GLKSFPYYELAQKQMRLPGGMLSFELKGGVKEGAVVMNNVKLCKLAVSLGDAETLIEHA
                     ASMTHSTYTKEELASAGISEGLVRLSVGLEDPEDIIFDLKQAL"
     aSDomain        8373..8813
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg68_14_Aminotran_5.1"
                     /evalue="1.30E-10"
                     /label="ctg68_14_Aminotran_5.1"
                     /locus_tag="ctg68_14"
                     /protein_end="235"
                     /protein_start="88"
                     /score="32.6"
                     /tool="antismash"
                     /translation="GMGAISAALWTALHAGDHVVASDTLYGCTFALLNHGMTRYGVEVT
                     FVDMADLDAVKKAMKPNTRVVYLETPANPTLKITDIHAVSEIAHSVEECIVIVDNTFCT
                     PYIQRPLLLGADVVVHSATKYLNGHGDVIAGFVCGKQEYINNV"
     CDS             9541..9936
                     /locus_tag="ctg68_15"
                     /transl_table=11
                     /translation="MNLQYVKGSYMDEIMFENRPVLFTLEGLPEGNDEEAVRYSKQIWE
                     WILEYRVRVIAHAPLIANFKNKKWREDGEPEVTSEEIRGYLERINSVYVQYQGGFDIFF
                     DTNDVFHEHSIVVSMGKNFMFKGFKLL"
     PFAM_domain     9571..9906
                     /aSDomain="DUF2262"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10020.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2262)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_15_0013"
                     /evalue="6.70E-07"
                     /label="ctg68_15"
                     /locus_tag="ctg68_15"
                     /protein_end="122"
                     /protein_start="10"
                     /score="30.0"
                     /tool="antismash"
                     /translation="MDEIMFENRPVLFTLEGLPEGNDEEAVRYSKQIWEWILEYRVRVI
                     AHAPLIANFKNKKWREDGEPEVTSEEIRGYLERINSVYVQYQGGFDIFFDTNDVFHEHS
                     IVVSMGKN"
     CDS             10001..10141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_16"
                     /sec_met_domain="TIGR03973 (E-value: 5.9e-24, bitscore:
                     74.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.3e-24, bitscore: 75.5,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHIITINTESIQKTAQYADCSECQTSCQSACKTSCTVGNQVCN
                     K"
     aSDomain        10007..10135
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_16_0005"
                     /evalue="1.40E-21"
                     /identifier="TIGR03973"
                     /label="ctg68_16"
                     /locus_tag="ctg68_16"
                     /protein_end="45"
                     /protein_start="2"
                     /score="74.1"
                     /tool="antismash"
                     /translation="KHIITINTESIQKTAQYADCSECQTSCQSACKTSCTVGNQVCN"
     PFAM_domain     10007..10138
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_16_0014"
                     /evalue="2.70E-21"
                     /label="ctg68_16"
                     /locus_tag="ctg68_16"
                     /protein_end="46"
                     /protein_start="2"
                     /score="75.3"
                     /tool="antismash"
                     /translation="KHIITINTESIQKTAQYADCSECQTSCQSACKTSCTVGNQVCNK"
     CDS             10203..11594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_17"
                     /sec_met_domain="PF04055 (E-value: 3.3e-15, bitscore: 47.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.2e-15, bitscore: 46.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.2e-20, bitscore:
                     64.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.2e-23,
                     bitscore: 72.3, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEKIRPMIHKYYQNGTYMLLDVNSGIMNVIDKITYDILDVYNGS
                     NREKVLKKFVSIYAQKDIEQVLDELDELIKKEMLFAPMCESFEVVADEEPVIKSLCLNI
                     AHDCNLRCKYCFASTGDYDTHKRELMSFDIAKHAVDLLIESTKNKRQHCEIDFFGGEPL
                     MNFDVVKQTIAYIREQEKIHDKIFKLSLTTNGMLLDDEKISYLTENHISLILSLDGRPE
                     VHDRMRPDAGGHDSYKRCAENQVKAAERRNGEEYYVRGTYTKYNLDFTEDVRHMVDLGF
                     EGLSMEPVVGDDLSYAITEEDLPEIYSEYDRLTNFYLKRYNEGRPFIYYHFIMDLYRGP
                     CIAKRLRGCGAGHEYMCVVPNGDIYPCHQFVGQDGYVIGNVYAGVTDKKLPKIFRDTHV
                     LNKPNCVKCWAKFFCSGGCHANNIKYGGAIENPYELSCHIQKKRIECAMYIQAVLAMQK
                     AKSSN"
     aSDomain        10227..11558
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_17_0006"
                     /evalue="8.50E-176"
                     /identifier="TIGR03974"
                     /label="ctg68_17"
                     /locus_tag="ctg68_17"
                     /protein_end="452"
                     /protein_start="8"
                     /score="583.2"
                     /tool="antismash"
                     /translation="IHKYYQNGTYMLLDVNSGIMNVIDKITYDILDVYNGSNREKVLKK
                     FVSIYAQKDIEQVLDELDELIKKEMLFAPMCESFEVVADEEPVIKSLCLNIAHDCNLRC
                     KYCFASTGDYDTHKRELMSFDIAKHAVDLLIESTKNKRQHCEIDFFGGEPLMNFDVVKQ
                     TIAYIREQEKIHDKIFKLSLTTNGMLLDDEKISYLTENHISLILSLDGRPEVHDRMRPD
                     AGGHDSYKRCAENQVKAAERRNGEEYYVRGTYTKYNLDFTEDVRHMVDLGFEGLSMEPV
                     VGDDLSYAITEEDLPEIYSEYDRLTNFYLKRYNEGRPFIYYHFIMDLYRGPCIAKRLRG
                     CGAGHEYMCVVPNGDIYPCHQFVGQDGYVIGNVYAGVTDKKLPKIFRDTHVLNKPNCVK
                     CWAKFFCSGGCHANNIKYGGAIENPYELSCHIQKKRIECAMYIQA"
     PFAM_domain     10512..10880
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_17_0015"
                     /evalue="4.70E-12"
                     /label="ctg68_17"
                     /locus_tag="ctg68_17"
                     /protein_end="226"
                     /protein_start="103"
                     /score="46.7"
                     /tool="antismash"
                     /translation="IAHDCNLRCKYCFASTGDYDTHKRELMSFDIAKHAVDLLIESTKN
                     KRQHCEIDFFGGEPLMNFDVVKQTIAYIREQEKIHDKIFKLSLTTNGMLLDDEKISYLT
                     ENHISLILSLDGRPEVHDR"
     aSDomain        11247..11513
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_17_0007"
                     /evalue="2.90E-18"
                     /identifier="TIGR04085"
                     /label="ctg68_17"
                     /locus_tag="ctg68_17"
                     /protein_end="437"
                     /protein_start="348"
                     /score="64.1"
                     /tool="antismash"
                     /translation="CGAGHEYMCVVPNGDIYPCHQFVGQDGYVIGNVYAGVTDKKLPKI
                     FRDTHVLNKPNCVKCWAKFFCSGGCHANNIKYGGAIENPYELSC"
     CDS             11619..11801
                     /locus_tag="ctg68_18"
                     /transl_table=11
                     /translation="MNKLKNVLLAVVFFYALYAIIHEGPSKIMISILLLDVFIYIMGCW
                     MKSNIRKKLHEKNRK"
     CDS             12003..12521
                     /locus_tag="ctg68_19"
                     /transl_table=11
                     /translation="MRKVAIIAVLVFVSSIVWFGSDYIEVPSQHAEVVIAEKPKKNDIY
                     VYITGAVRKPGLYSFSETVRVGDAVHGAGDMVLYADPDSVNMAELIHDGMHIHIPYHLE
                     GIPTQAGGDVININQATEAELCTLPGVGPSMAKKIIDYRNEHGAFQSGDDLKKVKGIGT
                     AKFDKIVSA"
     PFAM_domain     12135..12296
                     /aSDomain="SLBB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10531.11"
                     /description="SLBB domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_19_0016"
                     /evalue="2.60E-06"
                     /label="ctg68_19"
                     /locus_tag="ctg68_19"
                     /protein_end="98"
                     /protein_start="44"
                     /score="27.3"
                     /tool="antismash"
                     /translation="YVYITGAVRKPGLYSFSETVRVGDAVHGAGDMVLYADPDSVNMAE
                     LIHDGMHIH"
     aSDomain        12336..12512
                     /aSDomain="TIGR00426"
                     /aSTool="tigrfam"
                     /description="TIGR00426: competence protein ComEA
                     helix-hairpin-helix repeat region"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg68_19_0008"
                     /evalue="1.80E-17"
                     /identifier="TIGR00426"
                     /label="ctg68_19"
                     /locus_tag="ctg68_19"
                     /protein_end="170"
                     /protein_start="111"
                     /score="61.2"
                     /tool="antismash"
                     /translation="GDVININQATEAELCTLPGVGPSMAKKIIDYRNEHGAFQSGDDLK
                     KVKGIGTAKFDKIV"
     PFAM_domain     12342..12509
                     /aSDomain="HHH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12836.9"
                     /description="Helix-hairpin-helix motif"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg68_19_0017"
                     /evalue="4.80E-21"
                     /label="ctg68_19"
                     /locus_tag="ctg68_19"
                     /protein_end="169"
                     /protein_start="113"
                     /score="74.9"
                     /tool="antismash"
                     /translation="VININQATEAELCTLPGVGPSMAKKIIDYRNEHGAFQSGDDLKKV
                     KGIGTAKFDKI"
ORIGIN
        1 ccaaataaat gcagctaaca ataataataa cctatatttc atgaaatatc ctttcgtaaa
       61 caaaaattaa tacgtatcgt attatactat actataaaag tgttttctac taaaaagaat
      121 atataaaata aaactaaaaa taatatacaa atcaatatat gtgaaaattt tcactgtatt
      181 tacagatgta aatattaaaa atcattggtc atatataaat gaatgatgta taatgtacct
      241 aatcataatt tggaggcgag tctattgtat acgaacgctt tgttaactga tctgtatcaa
      301 ttgacgatga tgcaaggctt attttttgaa ggcaagcata accagccatg tgttttcgac
      361 agatattaca gaacgaatcc ttttaaaggc ggttataccg tcgtagctgg gttggagcat
      421 ttgattgatt atgtgcagaa tatgcatttc agtgatgatg acatatatta tctgaaaagt
      481 acaaacttgt ttaaagaaag ctttttggac tatttaaaag atatgcattt tacgggtgat
      541 atttatgcga tgccggaagg aaccgttgcc ttccctcagg aagtgctgct tcggatacac
      601 accactaagg atgagtcatt attgctggaa accgcaatgt ctatgattat gaaccatgaa
      661 agcttgatag ctactaaagc acgccgtgtt cgtacagttg caggcaatga tacgcttatg
      721 gaattcggat tgcgtcgggc acagggaatg tcagcaggtg tttatggggc tcgttctgct
      781 atgattggcg gttttaatgg tacgagtaat gtattgtctg gagctaagtt tggcatgcct
      841 attttaggaa ccatggcaca tagctggatc atgagttttc cgtcggaact tgaagcattt
      901 catgcataca tccgccaata tcccaataat ttaatacttt tggcagatac gtacaataca
      961 ttgaagcagg gagtacctga tgcaattacc gtatttcagg aaatgaagga tgcagggaca
     1021 ttgcctaaga aatttggtat tcgtctcgat agcggtgatt tagcgtactt atcaaaagaa
     1081 gctaaaaaaa tgtttgatgc agctggattt cctgatgtca ttatatcggc ctcaaatgac
     1141 ttggacgagt ttcttatttc tgaactaaaa ctgcagggat gtgctataaa ttcgtgggga
     1201 gtagggacgc atttgataac tgctgaagac agtccgtctt tgggaggcgt atttaaactt
     1261 gtgggacagt atgatggtga tgtgtttgta ccgaaaatta agatgagtga taatgcggaa
     1321 aaaatttcta atccgggtat caagaatgtc tatcgtattt atgacagaga gagtaagaaa
     1381 atgaaagcag acatcattgc ccttgaagga gaaaaatttc cgacaataaa aaaccttcaa
     1441 ctcgtcagtg ataaaacacc ttggcgctct cgcgttattt atgctaatag ttttgatgtt
     1501 tgcccgatgc tgcagcctat ttttcaaaaa gggaagctgg tatatcataa acctacgttg
     1561 gcggcaattt gtgattatgc agatgaacaa atacagacac tttggccgga ataccttcgt
     1621 ctcgttaatc cagaggaaat gtgggtacaa cgaagttcta aactttctaa gctgcgtaat
     1681 aagattttgc aggaggaatc agcaaaattt atgtaatttt atgatatcaa ggcagaacga
     1741 gatattctcg tctctgcctt ttttatagaa aaaataccct tgtactgtaa gatgtgttta
     1801 tctatcttta cttgtgatat aatacctaat acggagaata ataatcgata ggagtgagta
     1861 tatgcgtggt gcaattctag gtgatatcgc cggttcatta tacgaggcaa ggtcgtatcg
     1921 cattaaaacg aaagagtttc ctttgttttc aaagaattcg cgttttacag acgatacagt
     1981 taccacggtg gctgtggcgg atgcattgat agaagcatat agagagaaaa aaggtctcag
     2041 tataccacta cgcaaaaaaa tgcagtattg gtgtcgaaaa tatccggatg cgggctacgg
     2101 tccttatttt aagaaatggt ttcagaccga ggcagcaaaa ccgtatggca gttatggcaa
     2161 tggggcggct atgcgtgtat caccagtcgc atgggtcgga aaatctttgc ctgaagttca
     2221 gtatctggca gaacttacag cggttgtgac acatgacaca caggaggcca taaccggagc
     2281 agttgctgtc gcttcggcta tttatctggc tcgtataaaa aagaataaag atagtatacg
     2341 ctcgtatata cagcaatatt attatccgat ggaacagtcc ttggatacaa ttcggctcaa
     2401 ctatcagttt acttccagaa cgcaggaaag tgttccgcag ggtattgagg cttttttgga
     2461 aagtgaaaat gtggaagatt ctatccgcaa tgcgatttcc ttgggaggcg atagcgatac
     2521 acaagctgct attgctgcca gtatagcgga agcttactat gggggcgtac cgcatacagt
     2581 atggcaggat gcattgcagc ggctgacacc ggaattaaaa gaggtactta gtatttttga
     2641 acatattttc aaatcgcaat attcctttta ataggagaag ggagctcaca gtgtgatcaa
     2701 ggagaaaagt ttttctgttc tttaccgaat tacagcaaac agtaaggaag aggctcaaaa
     2761 tttagctcag aaaattgcgg tagaacagac tatcgaattt ccgcctgact tagtagagag
     2821 acagtctatt ttcgataata tagttggaaa tattgagttt gcagaatacg gtgatggaca
     2881 atatcggtat tggataacat ataatgatgg ggctgcagga accgaaatta cgcagttatt
     2941 caacgttgtt tttgggaata gcagtatgca gccgggcata tgggtagaag atgttacatt
     3001 ctcttctgct tttttatcgg agtatcatgg acctcatttt ggcattgccg gtattcgtaa
     3061 acttttaggt gtgtttcacc ggcctttact gcattgtgta attaaaccat tggggtcaac
     3121 tacggcagag ctggctcgta tggcgtatga gtttgcagca gggggagcag atcttattaa
     3181 agatgatcat ggcattacca atcaggccag tgctcctttt gctgaacggg tagctgcgtg
     3241 tgccgatgcg gtacagaaag caaatgagga cactggcggg catgctgttt atgttgctaa
     3301 ttgcacggcg gatggaacga aaagccatga aagagcgttg caagctaaaa aattaggggc
     3361 cgggggtatt ttgctggcac ctgtgcttac ggggtttggc atgattcgtg aaatcgcgga
     3421 tgatcctttg gtgggattgc cgataatttc tcatccatcg ttatcaggag gatttattat
     3481 gccaggtcct tccggtgttg ttatgtccgt cttgtatggc atattttcac gtcttgccgg
     3541 tgcggatgct gttgtatttc ccagttatgg cggcagattt actttcacgg cagaggattg
     3601 cagaaaaatt gctgaatcag ctagaaagca tttgggagaa ttagcggcga tttttcccag
     3661 tcccggcggg ggtataacag aagagacgat tcctaaactg gcacaattat atggccggga
     3721 tgttatatat ttggtgggcg gcggtatttt tcgtcatgga ccggatttgc ttgaaaatac
     3781 gaaattttat aaaatgatga tacaggagat atactcgtga atacagaaca aaaatatgaa
     3841 aaactaaaag aaatcttaaa agatatgggc agtgttgtta ttggcttttc cggcggggta
     3901 gacagcacgc tgctctctta tacggcatat accgtattag gagagcaggc actggctgtt
     3961 acggcagtat ccccaacgct tcctgcaagt gaacggtccg atgcggagag tttggctaag
     4021 gtaataggaa taccccatcg ggaagtattg tcgacagaat ttgataatcc ggattttgtg
     4081 cgtaatccga aagaacgctg ctatatttgt aaaaaaatca gatttgaagc actggtgaaa
     4141 ctagcacaaa gcgaaggata tcattgggta attgatggcg gtaacataga tgatctcgat
     4201 gattaccgtc cgggaatgaa agcactgcag gaattatccg accatgtgcg cagtccgatg
     4261 atcgaagcag gattgggaaa agctgatatc agaatcattt ctcgtacatt agggcttcgc
     4321 acgtgggata aacaaagtgc agcttgtctt gccagccgaa ttccgtatgg aatggaacta
     4381 acaccggaac gattggagca gattgataaa gcagaaactt atattgcacc ttttattcat
     4441 ggatccctgc gggtgaggta tcatggcgat attgcacgta ttgaagtggg gatggaggaa
     4501 ttaaatgtta tattgaaaca tcggcaaagt atcgtaaaag ctttaaagaa atgtggattt
     4561 acatatgtaa cacttgactt gggtggatat gaaatgggaa gcttgaatga aggaatcagt
     4621 gtgaaagagg aataggataa tatggcaatc acaaaaaaaa taaagcaaga aatgttagaa
     4681 cgattccaac aacagtatgg tatattgaaa ccggccttgc attatcattc cccttttgaa
     4741 cttttggtag ccgtcgtttt atcggcacaa tgtactgatg aacgagtgaa tattgtaaca
     4801 gaagatttat ttcctctata taatacgcca aaaaaaatgc ttgaactggg tttgttggga
     4861 ttggaaagta aaatacgtac gtgtggtctc tatcatagca aagcgcagca tttactggaa
     4921 accagtgtaa ttctttgtga aaaatatgat ggggaagtgc cgcagtcttt tgaagaactt
     4981 gttaaacttc ctggtgttgg ccgaaaaaca gccaatgttc ttgtgagcat tctttttaat
     5041 ataccggcaa ttgcggtaga tacgcatgta tttcgtgttg caaatcgcac agaattggct
     5101 gtaggaaaaa ctccgttaga cgtagaactg gggttacaga aagctattcc aaaaaaatgg
     5161 tggagtcggg cacatcactg gctcatttgg catggcagaa gaatttgcaa agctcggaca
     5221 ccgttgtgtg atgactgtat attgaatgat ctatgcccgg cagcggcatt gaaagattca
     5281 tgatattaaa atataggtag tgtagtaata acggacaata tattcttgtc atatatatga
     5341 tgagaatata ctgtccgtta tttttttgga aaaatcatga aatagacaca ttgccggatt
     5401 tttggctgcc tatccgagaa tgtgtctatt tcatgattac atggtaacag aacaaattat
     5461 atacttgccg aattttgtct gctgataatt atttttctgt catatctgga gtcattggtt
     5521 gagaagcaca tagcgtagta tctttaatag gggtcttaaa tttgggtatt cccaatacga
     5581 tagctagtat agaagatatg cctaaaagat agggataaca tagatacccc attattgaaa
     5641 aaggtgaaat ggcagcaaga ctggaagcga ctaaaagttg agctccataa ggaatgcagc
     5701 cttgtataaa acaggcaaaa gtatctaaaa ggctcgctgt ttttctccta tctacaccat
     5761 atttttcaga taaatctttg gctagtgaac ctactatgat aatagaaaca gtattgtttg
     5821 ctgtacataa atcgactaaa ctgactaata taccaatacc caattctgca cctttttcgg
     5881 aatgaatctt tttttgtata gtgtgtaata aaaaatcaat accgccattg atttttgtta
     5941 actcacccat tccaccaatt aatattgata tgatagagat atcttccata ccggaaatac
     6001 cttttaaaca aagctgaaat actgtaaata tatcaaagga accatatatc atgccaatta
     6061 cagctgataa tataattccc ccgactaata ccagcacaac gtttaaaccg gttagggcaa
     6121 ctgtaagtac tgctatataa ggtaatattt tgaagaattg ataatcatac gtttccgtag
     6181 cattgacatc catgcccaac gttagacaag catatataat tagcgttatg atagctgccg
     6241 gcaatacgat tttaaaatta gctttgaatt tgtctaccat ttcaacatcc tgtgttttag
     6301 tggcagctac agtggaattt gatatcatgg ataacccgtc gccaaacata gcaccgctta
     6361 cgacagcggc aattaggaaa ccgacaggca accctgtttt ttctgctatt ccaacggcaa
     6421 taggagccag tgttactatg gtcccgacag aagtgccgag ggacatagat aaaaaggaac
     6481 caattacgaa catgccggcg accataagac taggtggaaa aatagttaat cctaagttta
     6541 ccgtagcatc tacagctccc attgctttac tgacttcagc aaaagcacct gctaaaataa
     6601 aaattaggca catcaatata atactggaat caccggcacc cttacaaaat cgttcaactt
     6661 tcaaatctat tggtatggtt ttattttgca gtatagctat ggtggatgca atgagtaaag
     6721 ctacaacaac aggcatttta taaaaatctt tcataatcag tgaaacccca agaaatagcg
     6781 ccataaatac aactagcggc agcagggcaa tagcattgcc ttttttttca ttcattatgg
     6841 tagtacctcc ttgaatgata agataaaatg ttcaattatt atttctcgat agtatggtag
     6901 tacctcctaa tttgtagtat tcccctcaga ttcatatggc tatagcgtat gaattcctgt
     6961 ttctgctata atatagaata tcattttaaa accggtttcg tgaaatatca ttttttgtta
     7021 aagttacata gtttaaagtt atgcaagaaa aggagactct atcatgacgt ttcagcaatt
     7081 aaaatatatt attgaaattt ctaagagccg ctctattacg gcggctgctc aaaatttgtt
     7141 tatttctcag cctagtctca gcaaatcggt gaaagaattg gaaacggaat taggaattac
     7201 tatattgaaa cgaacaagac atggaatatc ttttacctca agcggcatgg aatttttaag
     7261 ttatgcctat cgtattgccg aacaaattga aggaatgcaa tcatattttc ggcaggatga
     7321 aacgaatgaa agaaaaatca acctttctat atcagcacag cattatatgt ttcctaccga
     7381 tgccttggtc cagtttatac aaaaagctga aaaatatcat agctatacag tcacaatgca
     7441 ggaaggaagg acaacccaag tcattcatga tgtacttgta cagcagagcc aaattggaat
     7501 tatatatgta tccaaagcta cggaaaaatt tatgcaccgg ctgtttcagc ataaaggatt
     7561 agaatttatt ccattccgcc aatatccacc gtatgtatat ctcagagcgc agcatccact
     7621 ggcatccaga aaacagatca acgtacgaga attggaaccc tatccgtatg tacgatacgg
     7681 acaaggacag gacccgtatc tttttttctg aagaagtcat tattccggat atgtcgaata
     7741 aaaagctgat ttacgtaaca gatcgttcca gtctgctgag tatgctgcgc aataccaatt
     7801 cttttaatat tgggacaggc tgcctgctgc cggatatagt gggagatgct attatttcta
     7861 ttcctgtaga agactgcatt gatatgatgg aaatcggctg gctgaagtta aagaatatga
     7921 aaatgactca agaaatgacc ttatatgtac agttattgga ggattcattg aatcgatgca
     7981 catgtggcag tatagcaact gaacagtcat agtttaaaac tatgcaagaa tgatagtaat
     8041 gggtattttt cagaagtaaa tttctatgat atgctcttct caaataaata attcaggagg
     8101 agataatcat ggaacaaaaa caattgcagg caatgggttt tgcaaccaaa gcaattcatg
     8161 gcggcacttc taaaaatact tttggtgcat taacttgccc tatctatcaa acttcgacgt
     8221 ttgtatttga ttcggcagaa caaggcggca gacgatttgc tttagaagaa ggcggatata
     8281 tttattcgcg tctgggcaat ccgacgaata cagttattga agaaaaatta gcgttgttgg
     8341 aagaagcaga aggctgtgtg gctacggcat ccggaatggg ggctatttcg gcggcacttt
     8401 ggacagctct ccatgcaggt gaccacgttg ttgccagcga tactctctat ggatgtacgt
     8461 ttgctctgct caatcatggc atgacgagat atggtgtgga agtaactttc gtagatatgg
     8521 cggatttaga tgctgttaaa aaggcaatga agcctaatac aagagtcgtt tatttagaaa
     8581 ctccggctaa tccaacattg aaaattacgg atattcatgc tgtcagtgaa attgcgcatt
     8641 ctgttgaaga atgtatagtt attgtggata atacgttctg tacgccgtat attcagcgtc
     8701 cactcctatt aggagccgat gttgtcgtcc attcggctac aaaatattta aatggccatg
     8761 gtgatgttat tgctgggttt gtatgcggga aacaggagta tattaataac gtcaggtttt
     8821 tcggtttaaa agatatgact ggggccgtac taagtccgtt tgatgcattt ttgattgccc
     8881 gcggtatgaa aacattagcg atccgaatgg atcggcattg cagcaacgca atgaaggtgg
     8941 cacagtttct agaaacccat ccggcagttg cttcggtgtc ctaccctggg ttaaaaagct
     9001 ttccctatta tgaattggca caaaaacaga tgcgtctgcc cggcggcatg ctttcttttg
     9061 aactcaaggg tggtgtcaaa gaaggagcag ttgttatgaa caacgtaaag ttatgcaaat
     9121 tggcggtttc tctcggcgat gcagaaacgt tgattgaaca tgcagcatcc atgacacatt
     9181 ctacttatac aaaagaggaa ttggcgagtg cggggattag tgaaggattg gtgcgtctgt
     9241 ctgttggatt agaagatcct gaagatatta ttttcgatct taagcaagcc ttggatttaa
     9301 ttatttaaca tgataagttt ctttattatg taagtaagga ctactgtctt tatcaaggga
     9361 gtagtccttt ttttgtgtat tattgtctat actgtacaaa gcaaatggaa ttgctggtta
     9421 ttatatatag ttatgcatgt ccgctaaaat atatgaatat ttcatttgac aaattgtaca
     9481 actctgctaa gatgaagtaa ggcattccta tatatattat ttaggggagg ttttctctat
     9541 atgaatttgc aatatgttaa gggcagttat atggatgaaa tcatgtttga aaacagaccg
     9601 gtcttgttta cgttggaagg gcttccggag ggaaatgatg aagaagctgt ccgctatagc
     9661 aagcagatat gggaatggat attggaatat cgcgtccgtg tcattgccca tgcgccgctg
     9721 atcgctaatt ttaagaataa aaaatggcgt gaggatggag aacctgaagt tacatcagag
     9781 gagatacgag ggtatttgga acggattaat tctgtgtatg tccagtatca aggtgggttt
     9841 gatattttct ttgatacgaa tgacgtattt cacgaacact ccattgttgt cagcatggga
     9901 aagaacttta tgtttaaagg gtttaagctt ctttgatatg ttgtagaaag gcatatcatg
     9961 tggtaaaata gtaatgatca taaatgcgag gtgaattcca atggaaaaac atattatcac
    10021 aattaatacg gaatctatcc aaaagacagc acaatatgca gactgcagcg aatgtcagac
    10081 atcctgtcag tccgcttgca aaacgtcttg tacggtaggt aaccaggttt gcaacaaata
    10141 agttattctt gagcagccct ttaccacaat ggtaaagggc tattcttatg catggaggaa
    10201 ttatgacgga aaaaattaga ccgatgattc acaaatacta ccaaaatgga acatatatgt
    10261 tacttgatgt aaacagcggc attatgaatg ttattgataa aataacgtac gatatacttg
    10321 acgtatataa cggcagcaat cgagaaaagg ttctgaaaaa attcgtttca atatatgctc
    10381 aaaaagatat agaacaagta ttggatgaat tagacgaact tattaaaaaa gaaatgcttt
    10441 ttgcacctat gtgtgagtct tttgaagtgg tagcagatga agaacctgtt attaagtcct
    10501 tatgtcttaa tattgcacat gattgtaatc tgcgctgtaa atattgtttt gcttctacag
    10561 gagactatga tacgcacaag cgggaattga tgagctttga catagctaag catgccgtgg
    10621 atttacttat tgaaagcacg aagaataaaa gacaacattg cgaaattgac tttttcggcg
    10681 gcgaaccgct tatgaatttt gatgttgtaa aacagaccat tgcttatata cgggaacagg
    10741 aaaagataca cgataagatt tttaaattat cgctgaccac caacggcatg cttctggatg
    10801 atgaaaaaat aagctattta acagagaatc atattagctt gattctcagt ttagatggca
    10861 gaccggaagt gcatgaccgc atgcgtcctg atgccggcgg acatgattcc tataagcgct
    10921 gtgcagaaaa tcaggttaaa gcagcagaac gccgtaatgg agaagaatac tatgtacgcg
    10981 gtacctacac gaaatacaat cttgatttta cggaagacgt tcggcatatg gttgatctcg
    11041 gcttcgaagg cctttctatg gaacctgttg tgggagatga tctttcgtat gcgatcacgg
    11101 aagaagattt gccggaaatt tattctgaat atgatcgttt gacgaatttt tatttaaagc
    11161 gatataatga aggacgtccg tttatatatt atcattttat tatggattta taccgggggc
    11221 cttgtattgc aaaacggctg cgtggctgtg gagccggtca tgagtatatg tgtgtcgttc
    11281 ctaatggaga tatttatccc tgtcatcagt ttgtagggca agatgggtat gttattggca
    11341 atgtctatgc aggtgttacg gataaaaaac tgccaaagat tttcagggat actcatgttc
    11401 tgaataaacc aaactgtgta aaatgctggg caaagttttt ctgcagcggc ggctgtcatg
    11461 ctaataatat taaatatggc ggggctattg aaaatccgta tgaattgagc tgccatattc
    11521 aaaagaaacg cattgagtgt gctatgtata ttcaagctgt tctggctatg cagaaagcta
    11581 aatccagtaa ctagaaaaat ctgtaagagg cgttggctat gaacaaatta aaaaatgtct
    11641 tattggcagt tgtctttttt tatgctttat atgctattat ccatgaaggt ccttcaaaga
    11701 taatgataag tattcttctg ctggatgtat ttatatatat catggggtgt tggatgaaaa
    11761 gcaatatacg taaaaaatta catgagaaaa atcgtaaata aaagaaccgc tgtattagtt
    11821 tgctctccga atgttggaca cattgggaga gcttttttgt gcttcagttt tatttgtaat
    11881 tagagaataa ttaaacttca tttaaacttg cattaaaata gcaggattga ttctgtctgt
    11941 aggagaaatg aggagataaa ccgtttattt attcgacatc aagtagataa ggagacacta
    12001 atatgagaaa agttgcaata attgctgtac tggtttttgt aagcagtatc gtatggtttg
    12061 gcagtgatta tattgaggta ccgtcgcagc atgcagaggt tgtaatcgca gaaaaaccta
    12121 aaaaaaatga tatttacgta tatattacag gtgcggttcg aaaacctgga ctgtactcct
    12181 tttctgaaac cgtaagagta ggggatgctg ttcatggtgc aggagacatg gtactgtatg
    12241 cagatcctga cagtgtaaat atggccgaat taatacatga tgggatgcat atccatattc
    12301 cgtatcattt agaagggata ccaacacagg ctggagggga tgtgatcaat ataaatcagg
    12361 caacggaggc tgaattgtgt acattgccag gggtaggtcc ctctatggca aaaaaaatta
    12421 ttgattatag aaatgaacat ggagcattcc aaagcggcga tgatttaaaa aaggttaaag
    12481 gaatcggaac tgcaaaattt gataagatcg taagcgccta ataacatagt ggatagaatc
    12541 gttttggaat ctgtgagata atactctaaa ctaaagtatt gagagttttt cgagtaactt
    12601 gaaaaacttc aaaggaggtt tagcgttgaa caccagggaa gttactcagc aatatcgtct
    12661 taatcaatgg atggagatca tacgagaatg tcgcagcagt gggcaatcgg tagctag
//
