LOCUS       NZ_CP138514.1          10843 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP138514.1 Variovorax paradoxus strain SPNA7 plasmid unnamed,
            complete sequence.
ACCESSION   NZ_CP138514
VERSION     NZ_CP138514.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:56:59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 309287
            Orig. end    :: 320130
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10843
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[314287:315130](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5843
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10843
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10843
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1464..2696)
                     /locus_tag="ctg2_285"
                     /transl_table=11
                     /translation="MSIFLSRATALAVVLLPCLATAAPLSLDAALELAARRSETARAAR
                     AGVLSATEAAQASAQLPDPVLRVGIDNLPATGPDRFHTARESMTMKRIGISQEWLSADK
                     RAARQAAADAAVGRERVQAQVAAAQVRLQAALAYLDAFYAGETLKLAVLAEHHAREELE
                     ASRARLSSAAGSSQEVLAMAGARGVSEDDAADIRQQQNAARVALERWVGVRTDELMPVG
                     ELPVPAEEAYVAGHATVAALQRDVDMARQAAAVTASNRKPNWTWELAYGQRSGYADMVS
                     VGVSIPLPVAPGERQDRDTAARLALVEKAEADLAEATRAAGAEYRALASDAERLQQRIE
                     RYRAGVVVPAGQRTAAATAAYRSSQASLVTLFEARHAELEAQRKLLALQRDLARTRIQL
                     AFRPLTAEVAQ"
     PFAM_domain     complement(1497..1997)
                     /aSDomain="OEP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02321.20"
                     /description="Outer membrane efflux protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_285_0002"
                     /evalue="1.30E-08"
                     /label="ctg2_285"
                     /locus_tag="ctg2_285"
                     /protein_end="400"
                     /protein_start="233"
                     /score="35.0"
                     /tool="antismash"
                     /translation="AGHATVAALQRDVDMARQAAAVTASNRKPNWTWELAYGQRSGYAD
                     MVSVGVSIPLPVAPGERQDRDTAARLALVEKAEADLAEATRAAGAEYRALASDAERLQQ
                     RIERYRAGVVVPAGQRTAAATAAYRSSQASLVTLFEARHAELEAQRKLLALQRDLARTR
                     IQLA"
     PFAM_domain     complement(2061..2618)
                     /aSDomain="OEP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02321.20"
                     /description="Outer membrane efflux protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_285_0001"
                     /evalue="1.10E-10"
                     /label="ctg2_285"
                     /locus_tag="ctg2_285"
                     /protein_end="212"
                     /protein_start="26"
                     /score="41.7"
                     /tool="antismash"
                     /translation="LDAALELAARRSETARAARAGVLSATEAAQASAQLPDPVLRVGID
                     NLPATGPDRFHTARESMTMKRIGISQEWLSADKRAARQAAADAAVGRERVQAQVAAAQV
                     RLQAALAYLDAFYAGETLKLAVLAEHHAREELEASRARLSSAAGSSQEVLAMAGARGVS
                     EDDAADIRQQQNAARVALERWVG"
     CDS             complement(2773..3162)
                     /locus_tag="ctg2_286"
                     /transl_table=11
                     /translation="MSGYRFPRRCMTAFLVVLSLLFSQLALASYVCPGAADAAATAGMA
                     MAPGEPCEGMDSAQPVLCHQHAADMSLSFEPVKAATPSLPAIVQVLAVPLVLAALAEPL
                     PRQALPERQHPPPDPVFLATLRLRV"
     CDS             3434..4540
                     /locus_tag="ctg2_287"
                     /transl_table=11
                     /translation="MPANSAPDAPQASTFADGLESPWGMEFMPDGSLLVTERRGRLRMI
                     SADGREISSVQGVPRVDHRDHGGLLDVTIDPAFASNRLVYLSYTKAGRGLHADRNGLTV
                     ARARLSDDGSRIDELKVLFRQTPGAVNGQNLGGRLAVSTDGHLFVTMGDRHAPQDRMRA
                     QALAYYQGKTVRIRTDGTVPDDNPFAAGHGARPEIWSRGHRNPQGAFVHPRTGLLWVAE
                     HGPQGGDEINIVRRGLNYGWPVVTFGCEYDTCAKIGEGTSRRGMEAPLAFWKTPKIAPS
                     NLILYTGDQFPAWKGNVFVGALAGKAVWRFELAGEDSAPRVVRREALFAELGERIRDLR
                     QGPDGGLYLLTDGAKARIVRVARADSML"
     PFAM_domain     3488..4513
                     /aSDomain="GSDH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07995.13"
                     /description="Glucose / Sorbosone dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_287_0003"
                     /evalue="1.50E-123"
                     /label="ctg2_287"
                     /locus_tag="ctg2_287"
                     /protein_end="360"
                     /protein_start="18"
                     /score="412.4"
                     /tool="antismash"
                     /translation="LESPWGMEFMPDGSLLVTERRGRLRMISADGREISSVQGVPRVDH
                     RDHGGLLDVTIDPAFASNRLVYLSYTKAGRGLHADRNGLTVARARLSDDGSRIDELKVL
                     FRQTPGAVNGQNLGGRLAVSTDGHLFVTMGDRHAPQDRMRAQALAYYQGKTVRIRTDGT
                     VPDDNPFAAGHGARPEIWSRGHRNPQGAFVHPRTGLLWVAEHGPQGGDEINIVRRGLNY
                     GWPVVTFGCEYDTCAKIGEGTSRRGMEAPLAFWKTPKIAPSNLILYTGDQFPAWKGNVF
                     VGALAGKAVWRFELAGEDSAPRVVRREALFAELGERIRDLRQGPDGGLYLLTDGAKARI
                     VR"
     CDS             4691..4978
                     /locus_tag="ctg2_288"
                     /transl_table=11
                     /translation="MINRSFAITALALGALAAGSAMAQDKPMADKMAAMEKCYGVSMAG
                     KNDCAAGPGTTCAGTSKVDYQGNAWKNVPAGTCTTIKTPKGMGSLAPIKS"
     PFAM_domain     4793..4957
                     /aSDomain="DUF2282"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10048.11"
                     /description="Predicted integral membrane protein
                     (DUF2282)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_288_0004"
                     /evalue="1.30E-26"
                     /label="ctg2_288"
                     /locus_tag="ctg2_288"
                     /protein_end="89"
                     /protein_start="34"
                     /score="92.5"
                     /tool="antismash"
                     /translation="MEKCYGVSMAGKNDCAAGPGTTCAGTSKVDYQGNAWKNVPAGTCT
                     TIKTPKGMGS"
     CDS             5001..5843
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_289"
                     /sec_met_domain="DUF692 (E-value: 5e-97, bitscore: 320.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDILAAGVGLKPEHYEAALGAHAEGLWFEVHPENYMVAGGPRIG
                     WLEAIRARHPVSLHGVSLSLAGEAEPDAAHLQRLAALARRIQPALISEHLAWATWNGQY
                     FPDLLPFPRSTAALHRIAGNIARTQDALGTAIAIENPSHYLHIDGHEWDEIDFLAELSR
                     RTGCRLLLDINNVYVSACNLGVSAAEWVDRFPQALVGEIHLAGHSADPTLGDALLIDSH
                     DAPIAPEVWQLYRRFVDRAGARPTLIERDGNVPAFEELMAEQQQAVAVLQRAAQEAMA"
     PFAM_domain     5019..5813
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_289_0005"
                     /evalue="4.50E-95"
                     /label="ctg2_289"
                     /locus_tag="ctg2_289"
                     /protein_end="271"
                     /protein_start="6"
                     /score="317.9"
                     /tool="antismash"
                     /translation="AGVGLKPEHYEAALGAHAEGLWFEVHPENYMVAGGPRIGWLEAIR
                     ARHPVSLHGVSLSLAGEAEPDAAHLQRLAALARRIQPALISEHLAWATWNGQYFPDLLP
                     FPRSTAALHRIAGNIARTQDALGTAIAIENPSHYLHIDGHEWDEIDFLAELSRRTGCRL
                     LLDINNVYVSACNLGVSAAEWVDRFPQALVGEIHLAGHSADPTLGDALLIDSHDAPIAP
                     EVWQLYRRFVDRAGARPTLIERDGNVPAFEELMAEQQQAVAVL"
     CDS             5840..6628
                     /locus_tag="ctg2_290"
                     /transl_table=11
                     /translation="MNTPTDQFQQAFAQALFVPQEAAHPAVRALAMQPAFAVYRNTVMK
                     ACIDALQANFPTVAQLVGEEWFRAAAALYVATDLPSDGRLLHYGAGFPDFLRGFEPAAE
                     LAYLPGVAQLDTLWREAHAAQDAPAADAAWIARRTPEQMAALALAPHPAARWAWFDEQP
                     VYSIWERHRRPGAVGDELAWRGEGALLTRPGDTVNWHEITRAGCTFLDACASGASLAEA
                     AERALAADPQADISAMFAALLRAGAFAGASASPASNERTP"
     PFAM_domain     5858..6127
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_290_0006"
                     /evalue="6.30E-21"
                     /label="ctg2_290"
                     /locus_tag="ctg2_290"
                     /protein_end="96"
                     /protein_start="6"
                     /score="74.5"
                     /tool="antismash"
                     /translation="QFQQAFAQALFVPQEAAHPAVRALAMQPAFAVYRNTVMKACIDAL
                     QANFPTVAQLVGEEWFRAAAALYVATDLPSDGRLLHYGAGFPDFL"
     CDS             6625..7110
                     /locus_tag="ctg2_291"
                     /transl_table=11
                     /translation="MSTTSQASASIEGGNRRGLRAHWNAVAERLTRLVAHDALALATRV
                     AVAAIFFYSGRTKVEGFLTLTDSAYELFRTEYKLPFVPPEIAAHLAAYSEHLFPLLLVL
                     GLFTRLSALALLGMTLVIQVFVYPDAWPTHLSWAALLLYLAGRGAGRLSLDHALGIR"
     PFAM_domain     6742..7005
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_291_0007"
                     /evalue="8.20E-21"
                     /label="ctg2_291"
                     /locus_tag="ctg2_291"
                     /protein_end="127"
                     /protein_start="39"
                     /score="74.5"
                     /tool="antismash"
                     /translation="ALATRVAVAAIFFYSGRTKVEGFLTLTDSAYELFRTEYKLPFVPP
                     EIAAHLAAYSEHLFPLLLVLGLFTRLSALALLGMTLVIQVFVY"
     CDS             7180..7986
                     /locus_tag="ctg2_292"
                     /transl_table=11
                     /translation="MPSTWFLDTPPAGQLLDAGAVAHLLDAGNEQAPALHMLDFINHLM
                     PVEYISLVQYIDGVPSQVEGHAMGRRDNITAECFSLYKKRFRQADDMTRLAARMGGEAA
                     AHAPVTALLYDAADIPDPAWREQIFIGRQLTGRLSFLYAPVPRTIFAINLYRNRQNGRF
                     AEADVAQLLGLAPLLKRAHRNALFAQLASPDTPLRVAGIERTLQRTAPQLSPREREVCA
                     RIACGIGADGIAADLGIAASSVATLRKRAYLKLAIHGRQQLLRFIH"
     PFAM_domain     7813..7977
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_292_0008"
                     /evalue="1.20E-09"
                     /label="ctg2_292"
                     /locus_tag="ctg2_292"
                     /protein_end="266"
                     /protein_start="211"
                     /score="37.7"
                     /tool="antismash"
                     /translation="QLSPREREVCARIACGIGADGIAADLGIAASSVATLRKRAYLKLA
                     IHGRQQLLRF"
     CDS             8074..9099
                     /locus_tag="ctg2_293"
                     /transl_table=11
                     /translation="MWVRNCWYVIAWDHEISADALFTRTVLDEPLLVYRTEGGELVAMQ
                     DRCCHRHAPLSRGRREGDCVRCGYHGLKFAADGVCVEAPGLASIPVKARVRTYPVVSHN
                     KWIFVWMGDPSLADRAQLPDNFSCDHPDWRYRPGYVHYDTPYLLVCDNLLDFSHLSYVH
                     EGTLGGSTAIAQAVPKIEKVPRGIRVTRHVPDVPPSPFWKSFQSFDRNVDRYFIYDFLL
                     PGTLLMKSGGAPVGQAEGEQRGGVQLHSCQALTPETATTTHYFFQQSHRSSIADPAVTE
                     TIYRGLVTAFEEDRDMITAQYLNIDPDVRMLPLAMDAALVQYRRLLQEEVEREQRASQA
                     G"
     PFAM_domain     8092..8340
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00355.28"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_293_0009"
                     /evalue="7.60E-18"
                     /label="ctg2_293"
                     /locus_tag="ctg2_293"
                     /protein_end="89"
                     /protein_start="6"
                     /score="64.3"
                     /tool="antismash"
                     /translation="WYVIAWDHEISADALFTRTVLDEPLLVYRTEGGELVAMQDRCCHR
                     HAPLSRGRREGDCVRCGYHGLKFAADGVCVEAPGLASI"
     PFAM_domain     8500..9066
                     /aSDomain="VanA_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF19112.2"
                     /description="Vanillate O-demethylase oxygenase C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_293_0010"
                     /evalue="6.30E-47"
                     /label="ctg2_293"
                     /locus_tag="ctg2_293"
                     /protein_end="331"
                     /protein_start="142"
                     /score="160.3"
                     /tool="antismash"
                     /translation="DTPYLLVCDNLLDFSHLSYVHEGTLGGSTAIAQAVPKIEKVPRGI
                     RVTRHVPDVPPSPFWKSFQSFDRNVDRYFIYDFLLPGTLLMKSGGAPVGQAEGEQRGGV
                     QLHSCQALTPETATTTHYFFQQSHRSSIADPAVTETIYRGLVTAFEEDRDMITAQYLNI
                     DPDVRMLPLAMDAALVQYRRLLQEEV"
     CDS             9144..10121
                     /locus_tag="ctg2_294"
                     /transl_table=11
                     /translation="MRRRFLTLGFTMLAALPLAGLAQGSFPGKPIRIVVTAQAGGANDF
                     VARLIGEHAAKALGQPFVVDNRAGANGAVGLGEVARAAPDGYTIAVTLGDSLINNVALY
                     KTLPYDPQRDFVFLTQVVRSPAILSANLELGVKDMEGFRKLAARPGQQLSYGTWGPGGL
                     GHLAGEALNRKLGAHMVHVPQRGEAPVMADLLSNTVSVGLTSAGLARQHVQAGKVVPLA
                     IMGRERSAVLPQVPTMRELGFDDPLFEAAVWIAFVAPAKTPPAVVERLTLALRNAAAMP
                     EVQARMAERGLEMLNTTPEQFSANYRRDFDVITRRMREFGIEAQ"
     PFAM_domain     9279..10055
                     /aSDomain="TctC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03401.16"
                     /description="Tripartite tricarboxylate transporter family
                     receptor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_294_0011"
                     /evalue="2.30E-67"
                     /label="ctg2_294"
                     /locus_tag="ctg2_294"
                     /protein_end="304"
                     /protein_start="45"
                     /score="227.1"
                     /tool="antismash"
                     /translation="VARLIGEHAAKALGQPFVVDNRAGANGAVGLGEVARAAPDGYTIA
                     VTLGDSLINNVALYKTLPYDPQRDFVFLTQVVRSPAILSANLELGVKDMEGFRKLAARP
                     GQQLSYGTWGPGGLGHLAGEALNRKLGAHMVHVPQRGEAPVMADLLSNTVSVGLTSAGL
                     ARQHVQAGKVVPLAIMGRERSAVLPQVPTMRELGFDDPLFEAAVWIAFVAPAKTPPAVV
                     ERLTLALRNAAAMPEVQARMAERGLEMLNTTPEQFSA"
ORIGIN
        1 ggcgaccagc tcgtagccca tggggccgcc ttccctgaac tcgaagcgca ccgggtcgcc
       61 cggcttgatc tcggggaatg catccgaggc ggtcttggca aagcccatcg tcatggcggg
      121 ccactggagc gtcgcgaccg gcccatgcga aatggtgatg ccgtcgggcg ccacgctctc
      181 gaccttgcct tcggcctggt gagtcaccac ggccgttgcc gagacgcttg cggtcggaga
      241 ggccgcaggt gccgccatgt tgccgagcac ggagcgcagc cgcgcttccg agtcgatcag
      301 gaactggccg ctggccacca cctcttcgcc ctcggccagg cccgagatga cctcggtgtc
      361 gtcgcccagg tccgtgcccg gcgagacgtc gcgcggctcg aaggcgccgt cggccttgcg
      421 cacgatgacg acggcacgcc ggccggtgcg gatcaaggcc tccgaaggca ccaccagccg
      481 gctgctcgcg ggcccggcta cctgcagccg cagcagcatg ccgggcgtga gctttccacc
      541 cctgttgtcg acctcgaagc gagccttcaa ggtgcgggtg gcggtgctga tctcgggcag
      601 gatctcgtcg agcgcaccgt cgaacgactg cgatgcgtcg gcctgcagaa cggccttggc
      661 cttctgcccg cgcgcgaggc gaagcgcctg cgcctccgga atctcggcca ccgcccagac
      721 cttctgcagg cccgcgatgc ggaacagcgt catgccgggc gtgaccgcga cgccttcgcg
      781 cacgcccagc tcggccacca cgccatcgac cggcgccgtg agcacgtagc gcgcctgcgc
      841 cgtgccgctt tcctcgctgc gccggatgag ttcggccgga atcgacagcg cccgcatgcg
      901 atcgcgggcc gcctcgacga gatcgggtga agcgcccgcg cgcctgagcg cgagccactc
      961 gttctgcggc ccgagccagt cgggcgcgaa gagggtggcc agggcctggc ccttgcgcac
     1021 gcgctccatc ggtgcgcgaa ccgacaggcg ctcgacgtag ccggccacgc gggtctgcac
     1081 cgcggcgttg agccgctcgt cgaactgcac ggaaccgatg gcttcgaacg aggacgatgc
     1141 ttcggtgcgc cgcaccttcg cataccggat gccgaggttc tgctgcacgg cggggctgac
     1201 cttcacgccc gcctcgccgg cagtgccggt gtcggcatac acgggcacca gctgcatgtc
     1261 catgaacggc gacttgccgg gcttgtcgaa gcgcgggccg ggcaccatcg ggtcatgcca
     1321 gtagaggacc ttgcgaccat cgggcgtggt ggtcgcggcc atcgaagcat ccgtggcgtg
     1381 acccgtcttg cggcccaggt agaaggcgcc ggcggcgagc agcagggcgg ccagcagcga
     1441 tacgcccacg gtgagttttc ggttcattgc gccacctcgg cagtgagcgg ccggaaggcc
     1501 agttggatgc gggtccgcgc gagatcgcgc tgcagcgcca gcagcttgcg ctgcgcctcg
     1561 agctcggcat gccgcgcctc gaacagagtg acgaggctcg cctggctgga gcggtaggcc
     1621 gccgtcgcgg cagccgtcct ctggccggca ggaacgacga caccggcgcg atagcgctcg
     1681 atgcgctgct gcaggcgctc ggcatcgctc gcgagggcgc ggtattcggc gccggccgcg
     1741 cgagtggcct cggccagatc ggcttccgcc ttctcgacca gcgccagcct cgcggcggtg
     1801 tcgcggtcct gccgttcgcc aggcgccacg ggcagcggaa tgctcacgcc gaccgacacc
     1861 atgtcggcat agccgctgcg ctggccgtag gcgagctccc aggtccagtt gggcttgcgg
     1921 ttggatgcgg tgaccgccgc cgcctgccgg gccatgtcca cgtcgcgctg cagcgcggcc
     1981 accgtggcgt gcccggccac ataggcctct tcagcgggca ccggaagctc gccgaccggc
     2041 atcagctcgt cggttcgcac gcccacccag cgttcgagcg ccacgcgcgc ggcgttctgc
     2101 tgctgccgga tgtccgccgc atcgtcctcc gagacgcctc ttgcacccgc catcgccagc
     2161 acctcctggc tgctgccggc ggccgatgac aggcgcgcac gcgaggcttc cagctcttcg
     2221 cgcgcgtggt gttccgcgag cacggcgagc ttcagggttt cgccggcgta gaaggcgtcc
     2281 aggtacgcga gcgcggcctg caggcggacc tgggccgcgg ccacttgcgc ctgcaccctt
     2341 tcgcgtccga ccgccgcatc ggcagcggcc tggcgcgccg cgcgcttgtc ggcggacagc
     2401 cattcctggc tgatgccgat gcgcttcatc gtcatcgatt cgcgcgcggt gtgaaagcgg
     2461 tccggccccg tcgcgggcag gttgtcgatg ccgacgcgca gcacgggatc gggaagctgg
     2521 gccgaggcct gcgccgcttc ggtggcgctc agcacgccgg cgcgggcggc gcgtgccgtc
     2581 tcggagcgtc gggcggccag ctcgagcgcg gcatcgaggg acaggggcgc ggccgtcgca
     2641 aggcacggca gcagcacaac agccaaggcg gttgcgcggg aaaggaaaat ggacatggca
     2701 actccgcgga cgaacgaggc aatcgctggc aagcggacgc gccgcaccag caccggtcag
     2761 ccgacggagg ggtcagacgc gaagtctgag ggtcgcaaga aaaacaggat caggcggcgg
     2821 atgctgccgc tcgggcagcg cctggcgcgg aagcggctcg gcaagcgctg ccagcaccag
     2881 cggcacggcc agcacctgca cgatggcagg cagcgaaggc gtggcggcct tcaccggctc
     2941 gaacgacagc gacatgtcgg cggcatgctg gtggcacagc acgggctggg cgctgtccat
     3001 gccctcgcag ggctcgcccg gcgccatggc catcccggcc gtcgccgctg cgtccgctgc
     3061 cccgggacag acgtagcttg ccagcgccag ctgcgagaac agcagcgaca ggaccacgag
     3121 gaacgcggtc atgcaacgtc gggggaagcg atagccgctc atgaggccac cagtgtatcg
     3181 ccggcaacag aatgttccga ggccttcgat cgcaggggta atagaaagga tggactgtcg
     3241 ggcttgcccg ctcgccgata agattttcga gcggcaacgt cgccgcggcc ctgcagcaac
     3301 caccgacatg agcacagcgc cgacagccct tcgtcgttca acttcgaggc ttgctgcact
     3361 gtcctggcgg cgacacggct ctggcgccgc gcttctcgca gcgctctggc tctggcctgc
     3421 tggtgcgccg gccatgcccg caaactccgc gccggatgcg ccgcaggcga gcaccttcgc
     3481 cgacggcctc gagtcgccct ggggcatgga gttcatgccc gacggcagcc tgctcgtgac
     3541 cgagcgccgg gggaggctgc gcatgatcag cgccgatggg cgcgagatct cgtccgtcca
     3601 gggcgttccg cgcgtggatc accgcgatca cgggggcctg ctggacgtca ccatcgatcc
     3661 ggcgttcgcc tcgaaccgcc tcgtctatct gagctacacc aaagccggcc gcggactgca
     3721 tgccgaccgc aacggcctga cggtggcacg cgcgcgcctc agcgacgacg gatcgcgcat
     3781 cgatgaactc aaggtgctgt tccgccagac gccgggcgcg gtgaacgggc agaacctcgg
     3841 cggacggctc gctgtttcta ccgacggcca tctcttcgtc acgatgggcg accgccacgc
     3901 gccgcaggac cgcatgcgcg cccaggcgct cgcctactac cagggcaaga ccgtgcgcat
     3961 ccgcaccgac ggcaccgtgc ccgacgacaa ccccttcgcc gcaggccacg gcgcgcgtcc
     4021 ggaaatatgg agccgcgggc atcgcaatcc gcagggcgca ttcgttcatc cccggaccgg
     4081 gctgctctgg gttgccgagc acggaccgca gggcggcgac gagatcaaca tcgtgcgcag
     4141 gggcctgaac tatggctggc cggtggtgac cttcggctgc gagtacgaca cctgcgccaa
     4201 gattggcgag ggaacatcga ggcgaggcat ggaagctccg ctggccttct ggaaaacgcc
     4261 gaagatcgca ccgagcaacc tcatcctcta caccggcgac cagtttcccg catggaaggg
     4321 caacgtcttc gtcggtgcac tggccggcaa ggccgtatgg cgcttcgaac tcgcgggcga
     4381 agacagcgct ccgcgcgtgg ttcggcgcga agccctgttc gccgaactgg gagaacgcat
     4441 ccgcgacttg aggcaagggc ccgatggcgg cctctacctg ctcacggacg gtgccaaggc
     4501 gcgcatcgtt cgcgtggcgc gggcggactc aatgctgtag ctggcggcgt tcccgatctc
     4561 gttcgctcgg aaaaaaaatc tgccgaatcg cgcagggccc tgtaaccccg gccacgcaca
     4621 tcgcgaacta gcaagtgact gcgcattggg cgcggttgca atttctcaat caattttttg
     4681 gagttcatcc atgatcaacc gttctttcgc gatcaccgct cttgcactgg gtgcccttgc
     4741 cgcgggctct gccatggcgc aggacaaacc gatggccgac aagatggccg ccatggaaaa
     4801 gtgctacggc gtctcgatgg ccggcaagaa cgactgtgcc gccggccccg gcaccacctg
     4861 cgcgggcacc tccaaggtcg actaccaggg caacgcctgg aagaacgttc cggccggcac
     4921 ctgcaccacc atcaagacgc ccaagggcat gggttcgctg gcgccgatca agtcctgatc
     4981 gcggcactgc gcacgctgcc atgtccgaca tcctcgcggc cggcgtcggc ctcaagccgg
     5041 agcactacga ggccgcgctc ggcgcgcatg ccgagggcct gtggttcgag gtgcaccccg
     5101 agaactacat ggtggcgggc ggcccgcgca tcggatggct cgaagcgatc cgcgcgcgcc
     5161 atccggtgtc gctgcatggc gtctcgctct cgctcgcagg ggaggcagag cccgatgccg
     5221 cgcatctcca gcggctggcg gcgctcgccc ggcgcatcca gcctgcgctg atctccgagc
     5281 acctggcgtg ggccacatgg aacggccagt actttccgga cctgcttcct tttccgcgca
     5341 gcaccgccgc gctgcaccgc atcgccggca acatcgcgcg cacgcaggac gcgctgggca
     5401 ccgcgatcgc catcgagaac ccgtcccact acctgcacat cgacggacat gaatgggacg
     5461 agatcgattt tcttgccgag ctgtcgcgcc gcaccggctg caggctgctg ctcgacatca
     5521 acaacgtgta cgtgtccgca tgcaacctgg gcgtctcggc cgcggagtgg gtcgaccgct
     5581 ttccgcaggc gctggtcggc gagatccatc tcgcaggcca cagcgccgac cccacgctcg
     5641 gcgatgcgct gctgatcgat tcgcacgatg cgcccatcgc accggaggtc tggcagctgt
     5701 accggcgctt cgtcgatcgc gccggtgccc ggcctacgct gatcgagcgc gatggcaacg
     5761 tgccggcgtt cgaggaactc atggccgagc agcaacaggc cgtggccgtg ctgcagcgcg
     5821 cggcgcagga ggccatggca tgaacacgcc gaccgatcaa ttccagcagg cctttgcgca
     5881 ggccctgttc gttccgcagg aagccgcgca tcctgcagtg cgggcgctcg ccatgcagcc
     5941 cgctttcgcg gtgtaccgca acaccgtgat gaaggcctgc atcgatgcgc tgcaggccaa
     6001 cttcccgacc gttgcgcagc tggtgggcga ggagtggttt cgcgccgccg ccgcactcta
     6061 cgtggcgacg gatctgccga gcgacggacg cctgctgcac tacggtgcgg gcttccctga
     6121 tttcctgcgc ggcttcgagc cggcggcgga gctcgcctac ctgcccggcg tggcgcagct
     6181 cgacacgctc tggcgcgaag cccatgcggc acaggacgca ccggccgccg acgccgcatg
     6241 gatcgcccgc cgcacgccgg agcagatggc ggccctggcc ctcgcgcccc atccggcagc
     6301 ccgctgggcc tggttcgacg agcaaccggt ctacagcatc tgggagcgcc atcgccggcc
     6361 gggcgcggtt ggcgacgaac tggcctggcg aggcgagggc gcattgctga cgcggcccgg
     6421 cgacacggtg aactggcacg agatcacccg ggccggctgc acctttctcg acgcctgcgc
     6481 cagcggcgca agcctcgccg aggcggcgga gcgcgcgctg gcggccgacc cgcaggccga
     6541 catctcggcc atgttcgcag ccctgctgcg cgccggtgca ttcgccggcg cttcggcttc
     6601 gcctgcatcc aacgaaagaa caccatgagc accacctccc aggcttccgc gtcaatcgaa
     6661 ggcggcaatc gccgcggtct tcgtgcgcac tggaacgcag tggccgaacg cctcacgcgc
     6721 ctcgtggccc acgacgcact ggcactggcc acgcgcgtgg ccgtggcggc catcttcttc
     6781 tactcgggcc gcaccaaggt cgagggcttt ctcacgctga ccgacagcgc ctacgagctg
     6841 ttccgcaccg aatacaaatt gccattcgtg ccgcccgaga tcgccgcgca cctggcggcc
     6901 tactcggagc atctgttccc gctgctgctg gtgctgggcc tcttcacgcg cttgtcggcg
     6961 ctggccctgc tgggcatgac gctggtgatc caggtcttcg tctacccgga tgcatggccg
     7021 acgcatctct catgggccgc gctgctgctg tacctggcgg gccgcggcgc cggccgcctg
     7081 tcgctcgacc acgcgctggg cattcgctga ccggccggcg cgcggcctgc gggcttccac
     7141 cctgttgaat cggacgcggc ttgcctatat tgggccgcca tgccttccac ctggtttctc
     7201 gacacgccac ctgcgggcca gctgctggac gccggcgccg tcgcgcacct gctcgatgca
     7261 ggcaatgagc aggcgcccgc gctccacatg ctcgacttca tcaaccacct gatgccggtc
     7321 gaatacatct cgctcgtgca gtacatcgac ggcgtgccgt cgcaggtcga agggcatgcg
     7381 atgggccggc gcgacaacat cacggccgag tgcttctcgc tctacaagaa gcggttccgg
     7441 caggcggacg acatgacccg cctggctgcg cgcatgggcg gggaggcggc ggcccatgca
     7501 cccgtcaccg ccttgctgta cgacgcggca gacatccccg acccggcatg gcgcgagcag
     7561 atcttcatcg gccggcagtt gacggggcgg ctgagctttc tctacgcgcc cgtgccgcgc
     7621 acgatctttg cgatcaacct gtaccgcaac cggcagaacg gcaggttcgc ggaagcagat
     7681 gtcgcgcagc tgctcggcct ggcgcccctg ctgaagcgtg cgcaccgcaa tgcgctgttc
     7741 gcgcagctcg catcgcccga tacgccgctg cgcgtggcgg gcatcgagcg cacgctgcag
     7801 cgcacggcgc cgcaactgtc gccgcgcgag cgcgaggtct gcgcgcgcat cgcctgcggg
     7861 atcggcgccg acggcatcgc cgcggacctg ggcattgccg cgtcgagcgt ggcgacgctg
     7921 cgcaagcgcg cctacctgaa gctcgcgatc cacggacgcc agcagctcct gcgcttcatc
     7981 cactagggtc gacccggagc cttttgtacc cttctacagg gacagacgaa agccgcgcga
     8041 attcctacat tgcctggact cttggagaca ggcatgtggg ttcgaaactg ctggtacgtc
     8101 attgcgtggg atcacgaaat ttccgcggat gcgctgttca cgcgcacggt gctcgacgag
     8161 ccgctcctgg tctatagaac cgaaggcggc gaactcgttg cgatgcagga ccgctgctgc
     8221 caccggcatg cgccgctgtc gcgcggacgc agggaaggcg actgcgtgcg ctgcggctac
     8281 cacggcctca aattcgccgc cgatggcgtc tgcgtggagg caccggggct ggccagcatt
     8341 cccgtgaagg cgcgcgtgcg gacctacccg gtggtctcgc acaacaagtg gatcttcgtg
     8401 tggatgggtg atccgtcgct cgcggaccgc gcgcagctgc cggacaactt ctcgtgcgac
     8461 caccccgact ggcgctacag gcccggctat gtccactacg acacgcctta cctgctggtc
     8521 tgcgacaacc tgctggactt ctcgcacctg agctatgtgc acgaaggcac gctgggcgga
     8581 tcgaccgcca tcgcccaggc cgtgccgaag atcgagaagg tgccgcgcgg catccgcgtg
     8641 acgcggcacg tgcccgacgt gcccccgtct cccttctgga agtcgttcca gagcttcgac
     8701 cgcaacgtcg accgctactt catctacgac ttcctgctgc ccggcacctt gctgatgaag
     8761 tcgggcgggg cgccggtggg gcaggccgaa ggcgagcagc gcggcggcgt gcagctgcac
     8821 agctgccagg cgctcacgcc cgagacggca accaccacgc actacttctt ccagcaatcg
     8881 caccgaagca gcattgccga ccccgctgtc accgagacca tctaccgcgg tctggtcacc
     8941 gcgttcgagg aagaccgcga catgatcacc gcgcagtacc tgaacatcga tcccgacgtg
     9001 cggatgctgc cgctcgcgat ggacgccgca ctggtccagt accggcggct gctgcaggaa
     9061 gaagtcgagc gcgagcagcg tgcctcgcag gccggctgac gcgccgcgcc gccccacatc
     9121 cagaacaact ccaggagacc cccatgcgcc gccgctttct caccctcggc ttcaccatgc
     9181 tcgccgcgct gccgctcgcc gggctcgcgc aagggagctt cccgggcaag ccgatccgca
     9241 tcgtcgtcac ggcccaggcc ggcggcgcca acgacttcgt cgcgcgcctg atcggcgagc
     9301 atgccgcgaa ggcgctgggc cagcccttcg tggtcgacaa ccgggccggc gccaacggcg
     9361 cggtgggcct gggcgaagtg gcgcgggccg cgcccgacgg ctacacgatc gctgtcacgc
     9421 tcggcgattc gctcatcaac aacgtcgcgc tctacaagac actgccctac gacccgcagc
     9481 gcgacttcgt cttcctgacg caggtcgtgc gcagcccggc catcctgtcg gccaacctgg
     9541 agctcggcgt gaaggacatg gaaggcttcc gcaagctcgc ggcgcggccg ggccagcagc
     9601 tcagctatgg cacctgggga ccgggcggcc tcggccacct ggcgggcgaa gcgctcaacc
     9661 gcaagctcgg tgcgcacatg gtgcacgtgc cgcagcgcgg cgaggcgccc gtgatggccg
     9721 acctgctgag caacaccgtg agcgtcggcc tcacgtcggc gggcctcgcg cgccagcatg
     9781 tgcaggcggg caaggtcgtt ccgctcgcga tcatggggcg cgagcgctcg gccgtgctgc
     9841 cgcaggtgcc cacgatgcgc gaattgggct tcgacgatcc gctgttcgag gcggcggtgt
     9901 ggatcgcgtt cgtcgcgccc gccaaaacgc cgcccgcggt ggtcgagcgg ctgacgctgg
     9961 cgctgcgcaa cgccgccgcc atgcccgagg tccaggcgcg gatggcggag cgcgggctgg
    10021 agatgctcaa caccacgccc gagcagttca gcgcgaacta ccggcgcgac ttcgacgtga
    10081 tcacccggcg catgcgggag ttcggcatcg aggcgcagta gccgcgccgc atcggcgtcg
    10141 aagtgccggc gctgggtgta cttcaccaag ccgtctttgc aaaaagagaa atgtcattat
    10201 agtcaaccac ttggttcact attttcaacc ttctccggga acaagacgat gaacatccct
    10261 gccaccgcgc gtccggccga cgcgctcgat tcgaactggt ccctcgtggc cgccggcgcg
    10321 ctgatgacct gcgtggccat cggcgtgctg ttttcgctgg ccgtttttct cgagccgatg
    10381 agcgcggcca ctggctggtc gcgcgcgggc atttccagcg ccatgacgct ggccttcctg
    10441 agcatgggcg tggccggctt cggctggggc gccttgagcg accgctacgg cccgcgcgtg
    10501 gtggtgctcg cgggcacggt gctgctcggg ctctcgacgg tgctggccag ccgcgcgtcg
    10561 accttgctcg agttccagct cttctacggc gtgctgatgg gcatcgccgc cggcagcttc
    10621 ttcgcgccgg tgatcgccac gactgcgtcc tggttcgaca ggcaccgcag cctggccgtg
    10681 tcgctggtgt cggcgggcat gggcgtggcg cccatgacca tctcgccgct ggccgcgtgg
    10741 ctggtgacgc actacgactg gcgcacggcc cagctgatca tcggcatcgg cgcgtggatc
    10801 gtgctgctgc ccgcggtctg gctcatccgc gcggcaccgc gca
//
