Select genomic region:
Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8
1.9
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP138513.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 289,573 | 330,130 |
Region 1.2 | LAP | 2,232,957 | 2,255,143 |
Region 1.3 | resorcinol | 2,759,612 | 2,800,593 |
Region 1.4 | terpene | 3,342,766 | 3,364,513 |
Region 1.5 | redox-cofactor | 3,412,571 | 3,434,776 |
Region 1.6 | T1PKS,NRPS | 3,538,897 | 3,589,368 | colanic acid | Saccharide | 9%
Region 1.7 | arylpolyene,resorcinol | 3,753,892 | 3,800,203 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 5%
Region 1.8 | NRPS,T1PKS | 4,135,909 | 4,203,762 | crochelin A | NRP + Polyketide | 42%
Region 1.9 | NRPS | 4,341,278 | 4,388,774 | bacillibactin | NRP | 15%

NZ_CP138514.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | RiPP-like | 309,288 | 320,130 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 289,573 | 330,130 |
Region 1.2 | LAP | 2,232,957 | 2,255,143 |
Region 1.3 | resorcinol | 2,759,612 | 2,800,593 |
Region 1.4 | terpene | 3,342,766 | 3,364,513 |
Region 1.5 | redox-cofactor | 3,412,571 | 3,434,776 |
Region 1.6 | T1PKS,NRPS | 3,538,897 | 3,589,368 | colanic acid | Saccharide | 9%
Region 1.7 | arylpolyene,resorcinol | 3,753,892 | 3,800,203 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 5%
Region 1.8 | NRPS,T1PKS | 4,135,909 | 4,203,762 | crochelin A | NRP + Polyketide | 42%
Region 1.9 | NRPS | 4,341,278 | 4,388,774 | bacillibactin | NRP | 15%
Region 2.1 | RiPP-like | 309,288 | 320,130 |

Compact view
NZ_CP138513.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 289,573 - 330,130 nt. (total: 40,558 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001077.1 |  | 0.18 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0001343.1 |  | 0.17 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001897.1 |  | 0.17 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000545.1 |  | 0.16 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0000527.1 |  | 0.16 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000668.1 |  | 0.16 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0000836.1 |  | 0.16 | Other | APE Ec | Escherichia coli CFT073
BGC0002008.1 |  | 0.16 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000529.1 |  | 0.16 | RiPP | microbisporicin A2 | Microbispora corallina

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001077.1 |  | 0.49 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0001343.1 |  | 0.48 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001897.1 |  | 0.48 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000545.1 |  | 0.47 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0000527.1 |  | 0.47 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000668.1 |  | 0.47 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830
BGC0000836.1 |  | 0.46 | Other | APE Ec | Escherichia coli CFT073
BGC0002008.1 |  | 0.46 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000521.1 |  | 0.46 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000529.1 |  | 0.46 | RiPP | microbisporicin A2 | Microbispora corallina

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 2 - LAP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,232,957 - 2,255,143 nt. (total: 22,187 nt) Show pHMM detection rules used
LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or TIGR03602) and not cyanobactin_synth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 3 - resorcinol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,759,612 - 2,800,593 nt. (total: 40,982 nt) Show pHMM detection rules used
resorcinol: DarB

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | resorcinol | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001526.1 |  | 0.22 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  | 0.20 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000938.1 |  | 0.19 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000880.1 |  | 0.19 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0000874.1 |  | 0.18 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0000780.1 |  | 0.17 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0001739.1 |  | 0.17 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001343.1 |  | 0.16 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000917.1 |  | 0.16 | Other | molybdenum cofactor | Rhodobacter capsulatus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001526.1 |  | 0.55 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001525.1 |  | 0.53 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0000938.1 |  | 0.51 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000880.1 |  | 0.51 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0000874.1 |  | 0.50 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0000780.1 |  | 0.48 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0001739.1 |  | 0.48 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001343.1 |  | 0.47 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000917.1 |  | 0.46 | Other | molybdenum cofactor | Rhodobacter capsulatus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,342,766 - 3,364,513 nt. (total: 21,748 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.33 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.24 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000640.1 |  | 0.20 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.20 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000646.1 |  | 0.18 | Terpene | β-carotein | uncultured bacterium
BGC0001120.1 |  | 0.18 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000664.1 |  | 0.17 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.17 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001227.1 |  | 0.16 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001579.1 |  | 0.16 | RiPP | duramycin | Streptomyces cinnamoneus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.66 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000656.1 |  | 0.57 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000640.1 |  | 0.52 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000630.1 |  | 0.52 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000646.1 |  | 0.50 | Terpene | β-carotein | uncultured bacterium
BGC0001120.1 |  | 0.49 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000664.1 |  | 0.49 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.48 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001227.1 |  | 0.47 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001579.1 |  | 0.46 | RiPP | duramycin | Streptomyces cinnamoneus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 5 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,412,571 - 3,434,776 nt. (total: 22,206 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001914.1 |  | 0.16 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.16 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18
BGC0002031.1 |  | 0.15 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001783.1 |  | 0.14 | Other | streptonigrin | Streptomyces flocculus
BGC0000495.1 |  | 0.13 | RiPP | actagardine | Actinoplanes garbadinensis
BGC0000528.1 |  | 0.13 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0002015.1 |  | 0.13 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001921.1 |  | 0.13 | Other | MS-271 | Streptomyces sp.
BGC0001674.1 |  | 0.13 | RiPP | MS-271 | Streptomyces mirabilis
BGC0000842.1 |  | 0.11 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001914.1 |  | 0.47 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18
BGC0001529.1 |  | 0.47 | Alkaloid | bezastatin derivates | Streptomyces sp. RI18
BGC0002031.1 |  | 0.45 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001783.1 |  | 0.44 | Other | streptonigrin | Streptomyces flocculus
BGC0000495.1 |  | 0.42 | RiPP | actagardine | Actinoplanes garbadinensis
BGC0000528.1 |  | 0.41 | RiPP | michiganin A | Clavibacter michiganensis subsp. michiganensis NCPPB 382
BGC0002015.1 |  | 0.41 | RiPP | aborycin | Streptomyces sp. ZS0098
BGC0001921.1 |  | 0.41 | Other | MS-271 | Streptomyces sp.
BGC0001674.1 |  | 0.41 | RiPP | MS-271 | Streptomyces mirabilis
BGC0000842.1 |  | 0.38 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 6 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,538,897 - 3,589,368 nt. (total: 50,472 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000427.1 |  |  | 0.70 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000979.1 |  |  | 0.65 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E9
BGC0000980.1 |  |  | 0.65 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 22D11
BGC0000457.1 |  |  | 0.64 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0000876.1 |  |  | 0.61 | Other | neopolyoxin C | Streptomyces tendae
BGC0001561.1 |  |  | 0.61 | NRP | curacomycin | Streptomyces curacoi
BGC0000953.1 |  |  | 0.55 | Saccharide | amicetin | Streptomyces vinaceusdrappus
BGC0001479.1 |  |  | 0.54 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0000921.1 |  |  | 0.54 | Other (Shikimate-derived), Polyketide, NRP | promysalin | Pseudomonas putida
BGC0000432.1 |  |  | 0.53 | NRP | streptothricin | Streptomyces rochei

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000427.1 |  | 0.68 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000979.1 |  | 0.66 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E9
BGC0000980.1 |  | 0.66 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 22D11
BGC0001561.1 |  | 0.66 | NRP | curacomycin | Streptomyces curacoi
BGC0000457.1 |  | 0.65 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0000876.1 |  | 0.64 | Other | neopolyoxin C | Streptomyces tendae
BGC0000953.1 |  | 0.61 | Saccharide | amicetin | Streptomyces vinaceusdrappus
BGC0001895.1 |  | 0.61 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0001479.1 |  | 0.60 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0000921.1 |  | 0.60 | Other (Shikimate-derived), Polyketide, NRP | promysalin | Pseudomonas putida

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 6, location 3538896 - 3589368:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (val - mal) + (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_3298: val - mal
  Search NORINE for peptide: strict or relaxed
  AMP-binding (213..608): val
  NRPSPredictor2: val
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      val
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFWIGGTFK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      100% (strong)
  PKS_AT (1340..1620): mal
  ATSignature: Malonyl-CoA, inactive
  Top 3 matches:
    Malonyl-CoA: 87.5%
    inactive: 87.5%
    Propionyl-CoA: 58.3%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 138.4
    inactive: 68.4
    Methoxymalonyl-CoA: 62.3
    Methylmalonyl-CoA: 54.7
    Propionyl-CoA: 36.8
    Isobutyryl-CoA: 27.1
    CHC-CoA: 22.6
    Benzoyl-CoA: 17.1
    fatty_acid: 16.0
    Ethylmalonyl-CoA: 15.3
    Acetyl-CoA: 15.1
    2-Methylbutyryl-CoA: 15.0
    trans-1,2-CPDA: 7.8
    3-Methylbutyryl-CoA: 0.0
ctg1_3299: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (479..882): X
  NRPSPredictor2: val, leu, ile, abu, iva
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DMpqwGGVyK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      60% (weak)

NZ_CP138513.1 - Region 7 - arylpolyene,resorcinol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,753,892 - 3,800,203 nt. (total: 46,312 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)
resorcinol: DarB

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | resorcinol | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000783.1 |  |  | 0.47 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001476.1 |  |  | 0.45 | Other (Nucleoside) | pseudouridimycin | Streptomyces sp.
BGC0001591.1 |  |  | 0.43 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  |  | 0.43 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000272.1 |  |  | 0.42 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  |  | 0.41 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001197.1 |  |  | 0.38 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000234.1 |  |  | 0.38 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000932.1 |  |  | 0.37 | Other | tropodithietic acid | Phaeobacter inhibens DSM 17395
BGC0001362.1 |  |  | 0.37 | Other | tropodithietic acid | Phaeobacter inhibens DSM 17395

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000783.1 |  | 0.57 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0001476.1 |  | 0.56 | Other (Nucleoside) | pseudouridimycin | Streptomyces sp.
BGC0001591.1 |  | 0.55 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.55 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000272.1 |  | 0.54 | Polyketide | spore pigment | Streptomyces collinus
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001197.1 |  | 0.51 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000234.1 |  | 0.51 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000932.1 |  | 0.51 | Other | tropodithietic acid | Phaeobacter inhibens DSM 17395
BGC0001362.1 |  | 0.51 | Other | tropodithietic acid | Phaeobacter inhibens DSM 17395

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP138513.1 - Region 8 - NRPS,T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,135,909 - 4,203,762 nt. (total: 67,854 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001023.1 |  |  | 0.70 | NRP, Polyketide | myxochromide S1 | Stigmatella aurantiaca
BGC0000389.1 |  |  | 0.68 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001050.1 |  |  | 0.66 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001135.1 |  |  | 0.66 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001833.1 |  |  | 0.63 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001131.1 |  |  | 0.62 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000301.1 |  |  | 0.62 | NRP | anabaenopeptin 908, anabaenopeptin 915 | Planktothrix agardhii NIVA-CYA 126/8
BGC0001844.1 |  |  | 0.61 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  |  | 0.61 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000426.1 |  |  | 0.61 | NRP | sevadicin | Paenibacillus larvae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001023.1 |  | 0.68 | NRP, Polyketide | myxochromide S1 | Stigmatella aurantiaca
BGC0000389.1 |  | 0.67 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001050.1 |  | 0.66 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001135.1 |  | 0.66 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001833.1 |  | 0.65 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001131.1 |  | 0.65 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000301.1 |  | 0.64 | NRP | anabaenopeptin 908, anabaenopeptin 915 | Planktothrix agardhii NIVA-CYA 126/8
BGC0001844.1 |  | 0.64 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001128.1 |  | 0.64 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000426.1 |  | 0.64 | NRP | sevadicin | Paenibacillus larvae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 10, location 4135908 - 4203762:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X) + (ccmal) + (ser) + (asp) + (thr - D-X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_3857: thr - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (497..900): thr
  NRPSPredictor2: thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      thr
    Single AA prediction:
      thr
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1591..1989): X
  NRPSPredictor2: glu, gln
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      glu, gln
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DvWNIGliHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      70% (weak)
ctg1_3858: asp
  Search NORINE for peptide: strict or relaxed
  AMP-binding (440..831): asp
  NRPSPredictor2: asp
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asp
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKVGHVGK
    Nearest Stachelhaus code:
      asp
    Stachelhaus code match:
      100% (strong)
ctg1_3859: ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (517..915): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
ctg1_3860: mal
  PKS_AT (544..831): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 75.0%
    inactive: 66.7%
    2-Rhyd-Malonyl-CoA: 58.3%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 143.0
    inactive: 87.6
    Methoxymalonyl-CoA: 68.0
    Methylmalonyl-CoA: 58.7
    Propionyl-CoA: 43.9
    Ethylmalonyl-CoA: 42.7
    2-Methylbutyryl-CoA: 26.2
    Isobutyryl-CoA: 21.1
    CHC-CoA: 19.6
    fatty_acid: 19.1
    Benzoyl-CoA: 17.2
    Acetyl-CoA: 12.4
    trans-1,2-CPDA: 0.0
    3-Methylbutyryl-CoA: 0.0
ctg1_3861: pk - X
  Search NORINE for peptide: strict or relaxed
  CAL_domain (49..487): pk
  minowa: NH2
  Prediction, score:
    NH2: 184.8
    Acetyl-CoA: 46.3
    AHBA: 8.6
    fatty_acid: 8.0
    shikimic_acid: 0.0
  AMP-binding (1159..1559): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DvWNIGliHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      70% (weak)

NZ_CP138513.1 - Region 9 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,341,278 - 4,388,774 nt. (total: 47,497 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000457.1 |  | 0.32 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001399.1 |  | 0.31 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001345.1 |  | 0.27 | NRP | myxochelin A, myxochelin B | Stigmatella aurantiaca Sg a15
BGC0000342.1 |  | 0.26 | NRP | enniatin | Fusarium equiseti
BGC0001637.1 |  | 0.26 | NRP | kleboxymycin | Klebsiella oxytoca
BGC0000313.1 |  | 0.26 | NRP | beauvericin | Beauveria bassiana
BGC0001873.1 |  | 0.26 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338
BGC0001833.1 |  | 0.25 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000417.1 |  | 0.25 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001132.1 |  | 0.25 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000457.1 |  | 0.66 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001399.1 |  | 0.64 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001345.1 |  | 0.60 | NRP | myxochelin A, myxochelin B | Stigmatella aurantiaca Sg a15
BGC0000342.1 |  | 0.60 | NRP | enniatin | Fusarium equiseti
BGC0001637.1 |  | 0.60 | NRP | kleboxymycin | Klebsiella oxytoca
BGC0000313.1 |  | 0.59 | NRP | beauvericin | Beauveria bassiana
BGC0001873.1 |  | 0.59 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338
BGC0001833.1 |  | 0.59 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000417.1 |  | 0.59 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001132.1 |  | 0.58 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 11, location 4341277 - 4388774:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser - X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_4014: ser - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (468..871): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLVDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1533..1925): X
  NRPSPredictor2: gly, ala, val, leu, ile, abu, iva
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAmlvGAICK
    Nearest Stachelhaus code:
      bht
    Stachelhaus code match:
      70% (weak)

NZ_CP138514.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
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Location: 309,288 - 320,130 nt. (total: 10,843 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001285.1 |  | 0.04 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001897.1 |  | 0.04 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001687.1 |  | 0.03 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0001343.1 |  | 0.03 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001285.1 |  | 0.20 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001897.1 |  | 0.18 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001687.1 |  | 0.16 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0001343.1 |  | 0.15 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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