LOCUS       NC_012483.1            10891 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_012483.1 Acidobacterium capsulatum ATCC 51196, complete sequence.
ACCESSION   NC_012483
VERSION     NC_012483.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:53:33
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3083821
            Orig. end    :: 3094712
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10891
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3088821:3089712](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5891)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(1343..2548)
                     /locus_tag="ctg1_2525"
                     /transl_table=11
                     /translation="MWNDSSSATTISVTTASTICSRSLRLCFSVTGCIRHCDDGRARSV
                     RICQITYRFTSDPTTASNTIGIRSQSVCSSSSGNKPLAAIDAPTPISSRNPLAAITAVQ
                     ALCRIANTRLLQPMTHRPRAATTGTGISCCTSPGFVVDPILLTSSRTALAGFSLARYME
                     PLASKRPSAYDETQMNATISVSKEDYLKAILEAESEGQAVQPVTLAHWLSVSPPAVTMA
                     LKRLKRDGFVDVKADGIIRLTALGKQTALRTARRHHLIERMLSEIFGMEWYQVHDEAER
                     LEHAVSDEFEAKLIEKLGEKGTCPHGNSMLPESPAQRRKKGLLPLSETSEGATYSVISL
                     YERDPKLLRFLHGFGIGPRTTLQVLAHNYDQTIVIQTPKGSATLGRPAAERVWVKKASK
                     SS"
     PFAM_domain     complement(1364..1576)
                     /aSDomain="FeoA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04023.16"
                     /description="FeoA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0108"
                     /evalue="4.70E-08"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="395"
                     /protein_start="324"
                     /score="33.2"
                     /tool="antismash"
                     /translation="PLSETSEGATYSVISLYERDPKLLRFLHGFGIGPRTTLQVLAHNY
                     DQTIVIQTPKGSATLGRPAAERVWVK"
     PFAM_domain     complement(1619..1822)
                     /aSDomain="Fe_dep_repr_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02742.17"
                     /description="Iron dependent repressor, metal binding and
                     dimerisation domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0107"
                     /evalue="8.00E-22"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="310"
                     /protein_start="242"
                     /score="77.2"
                     /tool="antismash"
                     /translation="TALGKQTALRTARRHHLIERMLSEIFGMEWYQVHDEAERLEHAVS
                     DEFEAKLIEKLGEKGTCPHGNSM"
     PFAM_domain     complement(1841..1999)
                     /aSDomain="Fe_dep_repress"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01325.21"
                     /description="Iron dependent repressor, N-terminal DNA
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2525_0106"
                     /evalue="1.00E-11"
                     /label="ctg1_2525"
                     /locus_tag="ctg1_2525"
                     /protein_end="236"
                     /protein_start="183"
                     /score="44.9"
                     /tool="antismash"
                     /translation="VSKEDYLKAILEAESEGQAVQPVTLAHWLSVSPPAVTMALKRLKR
                     DGFVDVKA"
     CDS             complement(2670..2918)
                     /locus_tag="ctg1_2526"
                     /transl_table=11
                     /translation="VVIDCKHVWDAISGYLDNTLAPEVREVVQKHLEHCSICSAVLDST
                     RNILILTADDRVFELPAGFSERLHARLDEEIRASSSP"
     PFAM_domain     complement(2805..2906)
                     /aSDomain="zf-HC2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13490.8"
                     /description="Putative zinc-finger"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2526_0109"
                     /evalue="1.40E-09"
                     /label="ctg1_2526"
                     /locus_tag="ctg1_2526"
                     /protein_end="38"
                     /protein_start="4"
                     /score="38.0"
                     /tool="antismash"
                     /translation="CKHVWDAISGYLDNTLAPEVREVVQKHLEHCSIC"
     CDS             complement(2909..3535)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 137;
                     E-value: 8.2e-42)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2527"
                     /transl_table=11
                     /translation="MTDTLAENGEARIIAAILAGQKELFHDLIRPYERHVYVMTFAILK
                     NEADAEEVTQEAFLKAWRALPSFRAESRFGTWLVSIALNEARGRLRRKNQAPTDSIDET
                     HEDGTPHVSPALLRDWREIPSEMLERAEVRTLLRAAIDHLPLIYREIFLLRDLEELSVN
                     ECAAALNISVSAAKVRLHRARLLLQKELAPQLKHLNPKRRWFPWS"
     aSDomain        complement(2963..3466)
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2527_0018"
                     /evalue="1.20E-29"
                     /identifier="TIGR02937"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="191"
                     /protein_start="23"
                     /score="101.0"
                     /tool="antismash"
                     /translation="LFHDLIRPYERHVYVMTFAILKNEADAEEVTQEAFLKAWRALPSF
                     RAESRFGTWLVSIALNEARGRLRRKNQAPTDSIDETHEDGTPHVSPALLRDWREIPSEM
                     LERAEVRTLLRAAIDHLPLIYREIFLLRDLEELSVNECAAALNISVSAAKVRLHRARLL
                     LQKEL"
     PFAM_domain     complement(2978..3130)
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2527_0111"
                     /evalue="1.40E-15"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="186"
                     /protein_start="135"
                     /score="56.7"
                     /tool="antismash"
                     /translation="LLRAAIDHLPLIYREIFLLRDLEELSVNECAAALNISVSAAKVRL
                     HRARLL"
     PFAM_domain     complement(3254..3454)
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2527_0110"
                     /evalue="7.40E-16"
                     /label="ctg1_2527"
                     /locus_tag="ctg1_2527"
                     /protein_end="94"
                     /protein_start="27"
                     /score="57.8"
                     /tool="antismash"
                     /translation="LIRPYERHVYVMTFAILKNEADAEEVTQEAFLKAWRALPSFRAES
                     RFGTWLVSIALNEARGRLRRKN"
     CDS             complement(3532..4008)
                     /locus_tag="ctg1_2528"
                     /transl_table=11
                     /translation="VIKLFAVCYQRFQSVASLLQSPFLLLVRLYWGWQFAQAGWGKMQH
                     IHKVTGFFQSLGIPFPAFNAHFVAGVEFFGGILLILGLASRLTGLILTINMLVAYWTAS
                     RDALFSVISDPGTFYGDAAYTFLFAALLVLIFGAGWISVDTLIAKQYRQRTQQA"
     PFAM_domain     complement(3697..3939)
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2528_0112"
                     /evalue="8.60E-18"
                     /label="ctg1_2528"
                     /locus_tag="ctg1_2528"
                     /protein_end="104"
                     /protein_start="23"
                     /score="64.8"
                     /tool="antismash"
                     /translation="LLLVRLYWGWQFAQAGWGKMQHIHKVTGFFQSLGIPFPAFNAHFV
                     AGVEFFGGILLILGLASRLTGLILTINMLVAYWTAS"
     CDS             complement(4096..5004)
                     /locus_tag="ctg1_2529"
                     /transl_table=11
                     /translation="MSEPRSQLREIQQRMAACVMQPLTAQHGMRRRSAAGISSEREAGA
                     IIAPNDRLSSFERLEIYNRQYWFRLFASFEEDFPGLQAVTGNRRFQRIMQGYLTDCPST
                     SFSLRNLGSRLVEWLQAHPELTAPHTELALELAALEWAHIEAFDNAAWPGLTPEQMAAL
                     GEDSRLTLQPYLRLIEAHSAIDDALIAVRNEDGSSDGSSNSASTGYAARRARRLRAMPR
                     EHIFIAVHRYDDSVYYRRIEREDYQLLRAIEQGCTLGEAIEAAFHGSQLSEEEQPAWLQ
                     SAFGYFATMGWFCNPPAENAL"
     PFAM_domain     complement(4648..4974)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2529_0113"
                     /evalue="2.40E-15"
                     /label="ctg1_2529"
                     /locus_tag="ctg1_2529"
                     /protein_end="119"
                     /protein_start="10"
                     /score="56.6"
                     /tool="antismash"
                     /translation="IQQRMAACVMQPLTAQHGMRRRSAAGISSEREAGAIIAPNDRLSS
                     FERLEIYNRQYWFRLFASFEEDFPGLQAVTGNRRFQRIMQGYLTDCPSTSFSLRNLGSR
                     LVEWL"
     CDS             complement(5001..5891)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2530"
                     /sec_met_domain="DUF692 (E-value: 2.5e-96, bitscore: 319.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPANRFNGFTDYGVGIGLRVPHYRHILENKPVVDWFEIISENYMV
                     DAGRPLTVLDSILEQYRVVQHGVSMYFGSADPLNREHLKRLKALVRRTGTPWLSDHLCW
                     GSVDGRYTHDLLPMPYTWEAVRKTAENIRHVQDFVEVPVVVENVSSYAEFHVSEMTEWE
                     FLNEVVEQADCGILLDVNNIYVSSQNHNFNPRTYVDAVPAERVAQIHIAGHSKFEKYIL
                     DTHDHPVLDPVWKLYERAIERCGPTATLLEWDDNIPTFDEVHAEALKANRYLAKAAQKL
                     AAHAETLEAETAAAR"
     PFAM_domain     complement(5070..5855)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2530_0114"
                     /evalue="4.10E-107"
                     /label="ctg1_2530"
                     /locus_tag="ctg1_2530"
                     /protein_end="274"
                     /protein_start="12"
                     /score="357.4"
                     /tool="antismash"
                     /translation="GVGIGLRVPHYRHILENKPVVDWFEIISENYMVDAGRPLTVLDSI
                     LEQYRVVQHGVSMYFGSADPLNREHLKRLKALVRRTGTPWLSDHLCWGSVDGRYTHDLL
                     PMPYTWEAVRKTAENIRHVQDFVEVPVVVENVSSYAEFHVSEMTEWEFLNEVVEQADCG
                     ILLDVNNIYVSSQNHNFNPRTYVDAVPAERVAQIHIAGHSKFEKYILDTHDHPVLDPVW
                     KLYERAIERCGPTATLLEWDDNIPTFDEVHAEALKANRYL"
     CDS             complement(5981..6274)
                     /locus_tag="ctg1_2531"
                     /transl_table=11
                     /translation="MKHSLKAMMLSAAVTGLLGATPVILHAAPVSSNATVNVAGQAMLG
                     AFAHGKKTAMGKHSCKGKNDCKGQGGCKSGDNGCKGKNSCKGKGGCNTEHPM"
     CDS             complement(6611..10315)
                     /locus_tag="ctg1_2532"
                     /transl_table=11
                     /translation="MSRLDLQRGSAFCLPRNTHSIVRRFHPSGWARPVVSGILLLAVFF
                     ALQARPAAAQEFRGTISGTVTDSTGAAIPGASVTVTETSSGTTAKTVSNGTGQYVIPLL
                     LPGHYTIAVQKTGFKQAVRKGIALDASAHLIIDLQMEIGSTAQTVTVTAAAPLLNTANG
                     SIGQTITTKEVADLPLNGRTPMMLSQLAIGVLDTAQPSQVHPFDNNGAAAWSIGGSPSQ
                     TSEILLDGSPDELWNYTLAYSPPQEAVQQVSVTAFDTDASFGHTQAGVINQILKSGGNH
                     IHGAAYEFGQISALDANSYINDQKGVPIAVTHFNQYGVEASGPVWIPHVYDGRNKLFWL
                     FAWEGLKDSQPSTDLATVPTAAERTGDFSALLPLGCPNGYKNGDSAVCSDGKPNPYQLY
                     NPFTATESGKTITRQPIPGNNFANAGISIDSVAANYLKLYPQPNTTGQANGEDNYISNA
                     PSIDNFNNELGRLDYNVTETTHLYFDIRHNIRTQSKNNFFNNIATGESLTRENWGATLD
                     GTHTFNPSTFMDVRFNWTYFNQIEGQPSDGVSPSTLGFPDSLAQNSQHLQIPYVEFGSC
                     GSQTSFQCLGGESYSHVPSQSYQIFGDVIKTVGKHNLKFGIDAREYRLDSIANKYPDGY
                     FQFGTNWVQQSSGSASPTFGGDLASFLMGLPTKGEYDINARSTFHTYYVGAFVQDDWRI
                     SPTLTLNLGLRFDHDSPYYEKFGRVVNGFDTTSQNPVAAQAEAAYAANPISQLPASQFQ
                     VLGGLTFPNSKNGAYYQTNSHWFSPRIGFSWSPSWLDNKTVVRGGFGMFVSQYTIANLA
                     GNGTWSSNPILNTEGFSASTTFNPTNNNYLSPSSTLGNPYPDGFSQPTGSSLGLATFDG
                     QNVINFIDPHPTDPYSLRWNIGIQQSLNANTMLEIDYVGNHMVHMPVSTVQYNDIPAQY
                     LSTLPTRDQNTINTLTQTVSNPFYNISQMKGTTIGKAKTVSVAQILSRYPQYDTGETGG
                     NQVGGTQNSQGVFEDNATIGQSFFNALDARIEHRMSHGLWLVANYSWSKLEDEDVFLND
                     TDPKPYKHISPFDFTNHFVLGGTYDLPFGKGKWIDVKSHWLNELVGGWVINGIYTYQTG
                     APIYWTYDMVTTGQPITINNKVVNNGSAISTSAFDLASADQFSYHIRTFPLTLSSIRQD
                     GINNLDSSVLKDFPIHGGTYFQLRFETFNTLNHPLFKAPGVDPTSKFGLITAQSNSSRQ
                     VQIGGRLVF"
     PFAM_domain     complement(9896..10138)
                     /aSDomain="CarboxypepD_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13620.8"
                     /description="Carboxypeptidase regulatory-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2532_0115"
                     /evalue="2.20E-20"
                     /label="ctg1_2532"
                     /locus_tag="ctg1_2532"
                     /protein_end="140"
                     /protein_start="59"
                     /score="72.8"
                     /tool="antismash"
                     /translation="TISGTVTDSTGAAIPGASVTVTETSSGTTAKTVSNGTGQYVIPLL
                     LPGHYTIAVQKTGFKQAVRKGIALDASAHLIIDLQM"
ORIGIN
        1 ggtaacggag ccatgggcgg ttgacgaact cgcccatccg cttgcggtcg ctggtgaagg
       61 ccaccagcgg gaagacggcg aaactcaact gcatgctgag gatgacctgg ctgaagatga
      121 gcaggttgga ggtgcccttt tcgccataga gggccgtcac aatcacggtg ggcacgatgg
      181 cggtgaggcg cgtgatgagg cggcgcagcc agtcggggag gcggatgttg agaaagcctt
      241 ccatgacgat ctggccggcg agggtgccgg taatggtgga gttctgcccg gaggcgagca
      301 gcgcgatggc aaacatcaga ctggccgcgc caaagccgac aagcgggctg agcagcttgt
      361 aggcatcgcc aatttcggcg acctcatagt ggccggtgcg atgaaagacg gcggcggcca
      421 ctatgagaat ggccgcattc acaaacagcg caagcgtgag cgcgatggcc gagtcaacgt
      481 tggcatagcg gatcgcctcg cgcttgccgc ccgcggtgcg ctcatatttg cgggtctgcg
      541 cgatggaaga gtgcaggtag aggttgtgcg gcatcaccgt cgcgccaaga atcgagatgg
      601 caatgtagag catgtctgag ttggtgacga tggccgcgtg gggcagcaag aggctggaga
      661 cgagcccgtg ccaggtcggg tgtgagacca cgatttcgat ggcgaagatg gccgagatgg
      721 ttccaatgag cgtgatgacg agggcttcaa gataacggaa gccgcgatgc tgcagcagga
      781 gaatgagcag cacatcaaag ccggtgatga gcacgcccac gatcagggga atgccgaaga
      841 gcaattgcag cgcaatggcc gagccgatga cctcggccag gtcgcaggcg gcaatggcaa
      901 tctcggcaaa gagccacagc gcattggaga caggcttgct gtattgctcg cggcaggcct
      961 gcgcgagatc gcggccggtg gcgatgccga gtttgagcgc gaggctctgg agcagaatcg
     1021 ccagcaggtt cgagaccatg atgacgaaga gcagcgtgta gccgtagcgg gagccggcgg
     1081 cgagatcggt cgcccagttg ccggggtcca tgtagccgac ggagatgagg aagccggggc
     1141 cgaggaagcc gagcatacgc agccagaaga agcgcgagcg cgagataggg accgtcgcgt
     1201 tgacctccgg catggaggga cggaggacgg gcgtctcggg cgctttctgg agggtggtct
     1261 gaggcatacg ccggctggaa atctccttag cgttagtatg ccacagaaat taactatggt
     1321 taattaagat gctttgctat cgtcaggagg attttgaggc ctttttgacc cagaccctct
     1381 ctgctgccgg gcggccgagc gtggccgagc ctttcggcgt ttggatgacg atggtctggt
     1441 cgtagttgtg tgcgagcacc tggagggtgg tgcgcggccc aatgccgaag ccgtgcagga
     1501 agcgcagcag cttggggtcg cgctcataga ggctgatcac agagtaggtc gcgccttctg
     1561 aggtctcgga gagtggcagc aggccctttt tgcggcgctg cgctgggctc tcgggcagca
     1621 tggagttgcc gtgggggcac gtgccttttt caccgagctt ttcaatcagc ttggcttcaa
     1681 attcgtcaga gacagcatgc tccaggcgtt cggcttcgtc gtggacctgg taccactcca
     1741 tgccgaagat ctcagagagc atgcgctcga tgaggtggtg acggcgggcg gtgcgcagcg
     1801 cggtctgctt gccgagcgcg gtaaggcgaa tgatgccgtc cgccttgaca tcgacaaatc
     1861 catcgcgttt gaggcgtttg agggccatgg tgacggcggg cggtgagacg gaaagccaat
     1921 gcgcaagcgt gacgggctgc acggcctgcc cttcggactc ggcctcgagg atagctttga
     1981 gatagtcttc ttttgagacg gagatggtcg cgttcatctg ggtttcatcg taagccgatg
     2041 gccgtttgct ggccagcggt tccatgtagc gggcaagcga aaagcccgcc aaagcggtac
     2101 gcgaagaggt gagaaggatg ggatcgacaa cgaatcccgg agaagtgcag caggagatgc
     2161 ccgtgccggt cgtagcagcg cgcgggcgat gggtcatggg ctggagcagt ctggtgttcg
     2221 caattctgca gagcgcctgc acggcggtga tggccgcgag tggattgcgg ctgctgattg
     2281 gcgtgggcgc atcgatggcc gccagcggct tgttgccgct ggaagagctg catacggact
     2341 ggctgcggat tccgatggtg ttgctggcag tggtgggatc gctggtgaat ctgtacgtga
     2401 tctggcagat gcgcacgctg cgcgcccggc cgtcgtcgca atggcggatg cagccggtaa
     2461 ccgaaaagca gaggcgcagc gagcggctgc aaattgtgct ggcggtggtg acgctgattg
     2521 tggtggcact ggaagagtca ttccacattc atctctttca tcacggatag agatgggccg
     2581 tcctcaggat gagcccgaat cggcaaggct gaagcgcctt cgcgagacgg gcgaaattcg
     2641 ctgatcctat cttccaatag gcgtccttgt cacggcgaac tggatgcccg tatctcttcg
     2701 tcgaggcgtg cgtgcaggcg ttcgctgaag ccggcaggca gctcaaagac gcgatcgtcc
     2761 gctgtcagga tgaggatgtt gcgcgtggag tcgagcactg ccgagcagat gctgcagtgt
     2821 tccagatgct tctgcacgac ttcgcgcact tctggcgcca gcgtgttgtc gaggtagcca
     2881 gagatggcgt cccatacgtg cttgcaatct atgaccacgg gaaccacctc ctttttgggt
     2941 tgagatgttt gagctgcggg gccagctctt tttgcagcag cagacgtgcg cgatgcagac
     3001 gaaccttggc ggcagagacc gagatgttga gcgcggccgc gcactcgttg acgctgagct
     3061 cttcgaggtc gcgcagcaga aaaatctccc gataaataag cggcagatgg tcaatcgcgg
     3121 cgcgcagcag ggtgcgcacc tcggcgcgct ccagcatctc ggagggaatc tcacgccagt
     3181 cgcgcagcag ggcgggggag acgtgcggcg tgccgtcctc atgggtctcg tcgatggagt
     3241 cagtgggcgc ctggtttttg cggcgcagcc ggccgcgcgc ctcattgagc gcgatgctga
     3301 cgagccatgt gccgaagcgc gactcggcgc gaaaggacgg aagcgcgcgc caggccttga
     3361 gaaaagcttc ttgtgtgacc tcttcggcgt cggcctcgtt tttgaggatc gcgaacgtca
     3421 tgacatacac atggcgttcg taggggcgga tgaggtcatg aaagagctct ttctggcccg
     3481 cgagaatagc ggcgatgatg cgtgcttcgc cgttctctgc gagagtatct gtcatgcttg
     3541 ctgggtccgc tggcgatatt gtttcgcaat caaggtgtca acagagatcc atcccgcgcc
     3601 gaagatgagt acgagcagag cggcgaagag gaaggtgtaa gcagcgtctc cgtagaatgt
     3661 gcccgggtcc gagatgacgg agaagagcgc gtcgcgcgag gcggtccagt aggcaacgag
     3721 catattgatg gtgaggatga ggccggtgag ccgcgaggca aggccgagaa tgagcaggat
     3781 gccgccgaag aactcgacgc cggcgacaaa gtgcgcattg aaggcgggga acggaatgcc
     3841 gagcgattgg aagaatccgg tgaccttatg gatgtgctgc atcttgcccc agccggcctg
     3901 cgcgaactgc catccccaat agaggcggac gagcagcagg aaaggactct gaagcagcga
     3961 ggccacggac tgaaagcgtt ggtagcagac ggcaaagagt ttgatcacgt tcgtatcctt
     4021 caaagccgcg cgaatttttt aagtgtgctg cggagctgcc ccgaatggca gctcgtgttt
     4081 tatgtgcggc aaaccttaga gtgcattttc tgccggaggg ttacagaacc agcccatggt
     4141 cgcgaaatat ccgaacgcgg actggagcca tgcgggctgt tcctcttcag aaagctgcga
     4201 gccgtggaag gcagcttcga tggcttcgcc aagagtgcag ccttgctcga tggcgcggag
     4261 caactggtag tcctcacgct cgatgcggcg gtaataaacc gaatcatcat accgatgcac
     4321 agcgatgaag atgtgctcgc gtggcatggc acgcaggcgg cgtgcgcggc gcgcggcata
     4381 gccggtggag gcgctgttgc tggagccgtc gctgctgccg tcctcattgc ggacagcgat
     4441 gagcgcgtcg tcaatcgcgg agtgcgcctc gatgaggcgc aggtagggct gcagcgtgag
     4501 gcgtgagtct tcgcccagcg cggccatttg ttctggagtg aggccgggcc atgcggcgtt
     4561 gtcaaaggct tcgatgtgcg cccactcgag tgcggccaat tcaagagcga gttccgtatg
     4621 gggcgcggtg agttcggggt gcgcctgcag ccactccacg aggcgcgagc cgaggttgcg
     4681 caggctgaac gaagtggagg ggcagtcggt gagatagccc tgcatgatgc gctggaagcg
     4741 gcggttgccg gtgacggcct gcaggccggg gaagtcctct tcaaagctgg caaagagccg
     4801 gaaccaatat tggcgattgt agatttcaag acgctcgaag gaactgaggc ggtcgttggg
     4861 agcaatgatg gcgccggctt cgcgctcgct ggagatgccg gcggcactgc ggcggcgcat
     4921 gccatgttgc gcagtgagcg gctgcatgac gcaggcggcc atgcgctgtt gaatttcacg
     4981 aagctggctg cgcggctcgc tcatcgtgcg gccgccgttt ctgcttccag tgtttcggca
     5041 tgagcggcga gcttctgcgc ggctttggcg agatagcgat tggccttgag agcctcggca
     5101 tgcacctcgt caaaggtggg aatgttgtcg tcccactcga gcagcgtggc ggtaggcccg
     5161 cagcgctcaa tggcgcgctc gtagagcttc cagacggggt cgagaacggg gtggtcgtgc
     5221 gtgtcgagaa tgtacttctc aaactttgag tgcccggcaa tgtgaatctg cgccacgcgc
     5281 tcggcgggca ctgcgtccac ataggtgcgc gggttgaagt tgtgattctg cgaggagacg
     5341 tagatattgt tcacgtcgag caggatgccg cagtcggcct gctcgacgac ttcgttcagg
     5401 aactcccact cggtcatctc ggagacgtgg aactcggcat agctggagac gttttcaacg
     5461 acaacgggaa cttcgacgaa gtcctgcacg tggcggatgt tttcggcggt cttgcgaacg
     5521 gcctcccagg tgtagggcat ggggagcaga tcgtgcgtgt agcggccatc caccgagccc
     5581 cagcagagat ggtcagagag ccatggagtg ccggtgcggc gcacgagcgc cttgaggcgc
     5641 ttgaggtgct cgcgattgag cggatcggca gagccgaagt acatggagac gccatgctgc
     5701 acgacgcggt attgctcaag aatgctgtcg agcacggtca gcgggcggcc cgcatcgacc
     5761 atgtaatttt ccgagatgat ttcaaaccag tcgacgaccg gcttgttctc gaggatgtgg
     5821 cgatagtggg ggacgcgcag gccgatgccg acgccgtagt cggtgaatcc attgaagcga
     5881 ttggcaggca tggtgcgggc tctgattcct gaatcttctt gagggagggt tgcgggtctg
     5941 ctgcaacggc gttgaccgga gacagcagac ccgcgggaga ttacatgggg tgttcggtgt
     6001 tgcagccgcc cttgcccttg cagctgttct tgcccttgca gccgttgtcg ccagacttgc
     6061 agccaccctg gcccttacag tcattcttgc ccttacaaga gtgcttgccc atggcggtct
     6121 tcttgccgtg agcgaaggcg ccgagcatgg cctggccggc aacgttcacc gtagcgttgg
     6181 aagagaccgg agccgcatgc agaataacgg gggtcgcgcc gagcagaccg gtgacggccg
     6241 cgctcagcat catggctttg agagagtgct tcatgagaaa tcctcctggg attgcagacc
     6301 cgccgttggg gagcggtctg tgcatggtta gagtaactgg agtggatgtg gttacaggcc
     6361 cgtgagaaat tttcttcgcg agtccggcgg agacttctgt gtgtcgtacg agctaaccgg
     6421 gtcgcatgga tggattgcgg cagtgttgcc ggtcctcggg ggcggccggg tttgatcgac
     6481 gccatgatag cgctttttta ggtgagcggt cgcggggagg ggccgggatt ggcttaaggg
     6541 gaagaaacaa atggcgcgag gctgtcaggc ctcgcgccga tcaaggaggt tggaacctga
     6601 gtgagtcagg ctagaagacc agccgtccgc cgatctggac ctggcgggag ctgttggatt
     6661 gtgcggtgat caggccgaac ttggaggtgg gatcgacacc gggcgctttg aagagcggat
     6721 gattcaaagt gttgaaggtt tcaaagcgga gctggaagta ggttcctccg tggatgggga
     6781 agtctttgag caccgaggag tcgaggttgt tgatgccatc ctgacggatg gaggagaggg
     6841 tgagcgggaa ggtgcggatg tggtacgaaa actgatccgc gctcgcgagg tcgaaggcgc
     6901 ttgtgctgat cgcagagccg ttgttcacaa ccttattgtt gatggtaatg ggctggccgg
     6961 tggtgaccat gtcgtaggtc cagtagatgg gcgcaccggt ctggtaggta tagataccat
     7021 tgatgaccca cccgcctacg agttcgttga gccagtggga tttgacgtcg atccacttgc
     7081 ctttgccgaa gggtagatcg taggtgcctc cgaggacaaa gtgattggtg aagtcgaagg
     7141 gcgagatgtg cttgtacggt ttgggatcgg tgtcgttgag gaagacgtcc tcgtcctcaa
     7201 gcttggacca actgtagttg gccacgagcc agagaccgtg agacatgcgg tgctcaatgc
     7261 gggcgtcgag ggcgttgaag aaagattggc cgatcgtggc gttgtcttca aagacgccct
     7321 ggctgttctg ggtgccaccg acctggttgc cgcccgtttc gcccgtatcg tactgaggat
     7381 agcgcgacag aatttgcgcc accgagaccg tctttgcttt tccgatcgta gtgcccttca
     7441 tttgcgagat gttgtagaag gggttggaga ctgtctgcgt aagagtgttg atcgtgttct
     7501 ggtcgcgagt cggtaaagtg ctgaggtatt gggcaggaat gtcgttgtac tgaacggtcg
     7561 aaacgggcat gtgcaccatg tggttgccga cgtagtcgat ctccagcatg gtatttgcgt
     7621 tcagtgactg ctgaatgccg atattccagc gcaaagaata ggggtctgtc ggatgaggat
     7681 cgatgaagtt gatgacgttc tgtccatcga aagtcgccaa accaagagaa gaacccgtgg
     7741 gctgcgaaaa tccatccggg taaggattgc caagcgtgga ggatggactc aggtagttat
     7801 tgttcgttgg attaaaggtg gtggaggcgc tgaagccctc ggtattgagg attgggttcg
     7861 aggaccatgt gccattgccg gccagattgg cgatggtgta ctggctgacg aacatgccaa
     7921 atccaccgcg aaccaccgtt ttgttatcca gccacgacgg cgaccaggag aagccgatgc
     7981 gcgggctgaa ccaatgggag ttggtctgat agtaagcgcc gtttttactg ttcgggaagg
     8041 taagaccgcc cagcacctgg aactggctgg cgggcagttg cgagatcggg ttggccgcat
     8101 aggctgcttc tgcctgcgcg gcgaccgggt tttgtgaagt ggtgtcgaag ccgttcacga
     8161 cccggccgaa tttttcgtag taaggggaat cgtggtcgaa gcgcagacca agattcagtg
     8221 tcagtgtcgg agagatgcgc cagtcgtcct gcacaaatgc gcccacatag taagtgtgga
     8281 aggtgctgcg cgcgttgatg tcgtactcgc ccttggtcgg caggcccatc aggaaggaag
     8341 cgaggtcacc gccgaaggta ggcgatgccg agccggaaga ttgctgcacc cagttggtgc
     8401 cgaactggaa gtagccatca ggatatttgt tggcgataga gtcaagccgg tattcgcgag
     8461 catcgatacc aaacttgagg ttgtgcttgc cgacggtctt aatgacgtcg ccgaatatct
     8521 gataggactg cgatgggaca tgtgaataag actcgccccc aaggcattga aagctggtct
     8581 ggctgccgca gcttccgaac tcaacataag gaatctgcag gtgctgagag ttttgggcca
     8641 gtgaatcggg aaagcccaga gtggaagggc tgacgccatc gctcggctgg ccttcaatct
     8701 ggttgaagta ggtccagttg aagcgtacgt ccataaaggt ggaggggttg aaggtgtgcg
     8761 tgccgtcgag cgttgcgccc cagttttcgc gagtgaggct ttcacctgta gcgatgttgt
     8821 taaagaaatt gttcttggat tgtgtgcgga tgttgtggcg gatatcgaag tagagatgcg
     8881 tggtctctgt gacgttatag tcgaggcggc ctagctcatt gttgaagttg tcgatgctgg
     8941 gtgcgttgct gatgtagttg tcttcgccgt ttgcctgccc cgtcgtattg ggctgcggat
     9001 agagtttgag atagtttgcc gcaacggaat cgatggagat gccagcgttg gcgaagttgt
     9061 tgccgggaat cggctggcgc gtgatcgtct ttccgctttc tgtggcggta aacgggttgt
     9121 agagctggta ggggtttggt tttccatcag agcagacggc agagtcgccg ttcttgtatc
     9181 cgttagggca accaagcggc aacaatgccg agaaatcgcc agtgcgttcc gccgccgtgg
     9241 gaacggtggc gaggtcggtg gagggctgcg agtccttcaa gccttcccac gcaaagagcc
     9301 agaagagctt gttgcggcca tcgtagacgt gtggaatcca gactggacct gaggcctcga
     9361 cgccgtactg gttgaaatgg gtgactgcaa tgggcacacc cttttggtca ttgatgtacg
     9421 agttggcgtc gagcgcggag atctggccga actcataagc agcgccgtgg atatggttgc
     9481 cgccggattt gagaatctga ttgatgacgc cggcctgcgt gtggccgaag gaggcgtcag
     9541 tatcaaacgc ggtgacgctg acctgctgca cggcttcctg cggcgggctg taggccaggg
     9601 tgtagttcca gagctcgtcg ggggagccgt cgagcaggat ttcgctggtc tgcgaggggg
     9661 agccaccgat gctccaggct gcggcgccgt tgttgtcaaa ggggtgcacc tgcgagggct
     9721 gcgccgtgtc gagcacgccg atggcgagtt gagagagcat catgggcgtg cggccgttga
     9781 gcgggaggtc agcgacttct ttggtcgtga tggtctggcc gatggagccg ttggcggtgt
     9841 tgagcaatgg ggcagccgca gtgacggtca cggtctgagc ggtgctgccg atttccatct
     9901 gcagatcaat gatgagatgg gcgctggcat cgagcgctat gcctttgcgg acggcctgct
     9961 tgaagcccgt tttttgcacg gcaatggtgt agtggccggg cagcagcagc gggatgacgt
    10021 actggcccgt gccgttggag acagtcttag cggtggttcc gctggaggtt tctgtcaccg
    10081 tgacgctggc acccgggatg gccgcgccgg tggagtcagt gacggtgccg gagatggtgc
    10141 cgcggaattc ctgcgcggcg gctggccttg cctgcaatgc gaagaagacg gccagcagga
    10201 gaattccgga gacgacgggc ctggcccatc ctgacggatg gaagcggcga acgattgagt
    10261 gcgtgttgcg cggcaggcaa aacgcactgc cccgctggag atccagcctc gacatagtta
    10321 cattcctttt ttcagtccgg atgaggcgcc gcccgcacgg gggaagacgg gtgaagccgc
    10381 tcgcggctgc tcagtggatg tgcggtactg tggtacgacc acttttcagt acggcaccga
    10441 gtctgcccct tccacctggc gactgtcaag agggaagaaa aggccgcttc aagacgccgc
    10501 cttgtttgtt gattcgatga gctttgtgct gatatttgag ctggaagtaa aggggcggaa
    10561 cgaggaaagc tcgccgccgc ctggcgagat gataaaacgc agagaggtgc gacctcatct
    10621 caggcgagat gcaacgctat tggaccgcag gaagcaaaga aaggaggcgg ataaggtcgg
    10681 cttcggcatt ccaggagggg tagaaatgag ccaatgtaaa acgattttgc tgggatgcgg
    10741 tgagctggtg tgagtatggc tcgcgggcgg cagggtaggc tccgggaccg gtagagtgga
    10801 actcggcaaa ccatgcggtt gcgagcgagt gcgtcacgcc gggatgccat tcgcgccacc
    10861 cggcggcggc gatttgcggc cccatgaagg t
//
