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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AP019004.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 97,255 | 108,088 |
Region 2 | ranthipeptide | 2,117,374 | 2,139,016 |

NZ_AP019004.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 97,255 - 108,088 nt. (total: 10,834 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000877.1 |  | 0.06 | Other | polyoxin A, polyoxin H | Streptomyces cacaoi subsp. asoensis
BGC0001057.1 |  | 0.05 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0000283.1 |  | 0.03 | Other (Cyclitol) | cetoniacytone A | Actinomyces sp. Lu 9419

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000877.1 |  | 0.24 | Other | polyoxin A, polyoxin H | Streptomyces cacaoi subsp. asoensis
BGC0001057.1 |  | 0.23 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0000283.1 |  | 0.17 | Other (Cyclitol) | cetoniacytone A | Actinomyces sp. Lu 9419

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP019004.1 - Region 2 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,117,374 - 2,139,016 nt. (total: 21,643 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.23 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.23 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.23 | Other | ectoine | Methylophaga thalassica
BGC0000854.1 |  | 0.18 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.18 | Other | ectoine | Methylophaga alcalica
BGC0000599.1 |  | 0.17 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000948.1 |  | 0.16 | Other | α-galactosylceramide | Bacteroides fragilis NCTC 9343
BGC0000805.1 |  | 0.15 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0001238.1 |  | 0.14 | Other | biotin | Aspergillus nidulans
BGC0001239.1 |  | 0.14 | Other | biotin | Aspergillus nidulans

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.56 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000852.1 |  | 0.56 | Other | ectoine | Sporosarcina pasteurii
BGC0000856.1 |  | 0.56 | Other | ectoine | Methylophaga thalassica
BGC0000854.1 |  | 0.49 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.49 | Other | ectoine | Methylophaga alcalica
BGC0000599.1 |  | 0.48 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000948.1 |  | 0.47 | Other | α-galactosylceramide | Bacteroides fragilis NCTC 9343
BGC0000805.1 |  | 0.45 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0001238.1 |  | 0.44 | Other | biotin | Aspergillus nidulans
BGC0001239.1 |  | 0.44 | Other | biotin | Aspergillus nidulans

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names