LOCUS       NC_021064.1            20270 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021064.1 Cutibacterium avidum 44067, complete sequence.
ACCESSION   NC_021064
VERSION     NC_021064.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:39:18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2093246
            Orig. end    :: 2113516
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20270
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2103246:2103516](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10270
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20270
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20270
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(1509..2810)
                     /locus_tag="ctg1_1934"
                     /transl_table=11
                     /translation="MKRFLGRHVAGAMVFVVFCVQFLVVTCSMGFPAFQDFGEWIYQAR
                     VVAGILAGEEPHVGTLITYPVPYFLPQALLSLCELIFGAVGGSTVFLFIHAAAAAWVSD
                     LLVVRRALPPVMTACVLAICVLGGSQYWNGYVGLYWGMVIIVGYLAVSDRNATRWPVVM
                     AFALATFFTHGIIFGCWGLVAGVRALTSRRIRDLIVGVVPAMALVLWYFLKSNEAKGRE
                     TGYESVTHFIEYRGYTLAKSGGYQNIIASSVGDHQIAPWLFYGGAILNFLFAVLLVVLV
                     VLSLVSWSTLWRTSRWQLLALVSLGAIAAIFPPYFLGIVNPGERVVPTLIVVLILMWPD
                     MVGTRVERAEGIVRKVLCLLLTIGLCATVVSASLAPRKVAQGGGRPSEVSKEILLTSAF
                     GHRLDQFREKVDAARAGDLNQPLAWTTSILVEGK"
     CDS             complement(2908..3795)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 265.9; E-value:
                     7e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1935"
                     /transl_table=11
                     /translation="MSGMMGGMRGIILAGGTGSRLHPITLGTSKQLMPVYDKPMIYYPL
                     TTLIFAGIRDVLVITTPHEAEAFRHLLGDGSQFGISIEFAVQPEPKGLAQAFTIGAEFI
                     GSDSSCLILGDNIFSGPGLGTRLQAKAQSVDGALVFGYRVADPSAYGVVEIDDDGFALS
                     IEEKPEHPKSHWAVPGLYFYDNDVVEVARGLRPSARGELEITDVNRTYMEQRRLHVELL
                     PRGTAWLDTGTFDSLNDAGNFVRAIQARQGLQVGCPEEAAWRCGFLSDDDLLARAGQFE
                     KSGYGAYLRGLLTS"
     aSDomain        complement(2917..3771)
                     /aSDomain="TIGR01207"
                     /aSTool="tigrfam"
                     /description="rmlA: glucose-1-phosphate
                     thymidylyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1935_0001"
                     /evalue="6.20E-135"
                     /identifier="TIGR01207"
                     /label="ctg1_1935"
                     /locus_tag="ctg1_1935"
                     /protein_end="293"
                     /protein_start="8"
                     /score="446.8"
                     /tool="antismash"
                     /translation="RGIILAGGTGSRLHPITLGTSKQLMPVYDKPMIYYPLTTLIFAGI
                     RDVLVITTPHEAEAFRHLLGDGSQFGISIEFAVQPEPKGLAQAFTIGAEFIGSDSSCLI
                     LGDNIFSGPGLGTRLQAKAQSVDGALVFGYRVADPSAYGVVEIDDDGFALSIEEKPEHP
                     KSHWAVPGLYFYDNDVVEVARGLRPSARGELEITDVNRTYMEQRRLHVELLPRGTAWLD
                     TGTFDSLNDAGNFVRAIQARQGLQVGCPEEAAWRCGFLSDDDLLARAGQFEKSGYGAYL
                     RGLL"
     PFAM_domain     complement(3064..3768)
                     /aSDomain="NTP_transferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00483.25"
                     /description="Nucleotidyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1935_0001"
                     /evalue="7.10E-62"
                     /label="ctg1_1935"
                     /locus_tag="ctg1_1935"
                     /protein_end="244"
                     /protein_start="9"
                     /score="209.3"
                     /tool="antismash"
                     /translation="GIILAGGTGSRLHPITLGTSKQLMPVYDKPMIYYPLTTLIFAGIR
                     DVLVITTPHEAEAFRHLLGDGSQFGISIEFAVQPEPKGLAQAFTIGAEFIGSDSSCLIL
                     GDNIFSGPGLGTRLQAKAQSVDGALVFGYRVADPSAYGVVEIDDDGFALSIEEKPEHPK
                     SHWAVPGLYFYDNDVVEVARGLRPSARGELEITDVNRTYMEQRRLHVELLPRGTAWLDT
                     GTFDSLNDAGNFV"
     CDS             4046..5386
                     /locus_tag="ctg1_1936"
                     /transl_table=11
                     /translation="MDSKNRQAHATGPSQVSRRSVAKGTAWAVSAITSMTLVPLVPAFA
                     ASAQRKQVTITFDAKKHKETIQCVRIPAEATDIRYSIRGGAGGAGPKDSWGERGGSGAE
                     VLGQIHRPGEGTAAAQEFTIWGVAGGYGPTAAWNDNAVEFATGYGNGGPSMGVPYHTSI
                     VSTEQWSERWCHGGGAGSAIAIGGDPEGPGQLVAVAGGGGAAGTGTYSREAANMGPNVW
                     PVREGGNGGNGGKSWDGADGGQSHYETKYAQVTAAGGSGARGGQGGNGGSTANTSYVPK
                     DLEFDKIIAGQAGGNHGSGNHGGGDGGAPVKFERRRSVRGDGHIDDYIALSSAAGGGGY
                     AGGGSGALVVISRDPILKWAASDVPGQLGAIGAGGAGSSYLAPSLDGGFSATGEIDFPD
                     TGGVRTNGTVHMAPSLPKNYGKPGNVTISFWVPEDMSSKPSDYTDKC"
     CDS             5687..6685
                     /NRPS_PKS="Domain: NAD_binding_4 (5-179). E-value: 2.5e-15.
                     Score: 48.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1937_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     272.4; E-value: 9.2e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1937"
                     /sec_met_domain="NAD_binding_4 (E-value: 1e-13, bitscore:
                     48.1, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.6e-11,
                     bitscore: 40.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.7e-12, bitscore:
                     42.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSLLVTGGAGFIGSNFAHWIINNTDATVTVLDAMTYAASEASLE
                     GLPRNRYQLVRGSVCDADLVDELVSHHDAVVHFAAESHNDNSLDGPAPFIQTNIVGTFT
                     LLQAVRKHEKRLHHISTDEVYGDLQLDDPTKFTPQTRYNPSSPYSASKASSDLLVRAWV
                     RSFGVQATISNCSNNYGPRQHVEKFIPRQITEILEGRRPKLYGSGLNVRDWIHVDDHNS
                     AVWTILERGTIGETYLIGADGELDNKTVIELILELMGQPIDGYDHVNDRPGHDLRYAID
                     ATKLRQELGWQPEYTNFRDGLAATIDWYRGNQSWWLPQKETTEAAYAAKGQ"
     CDS_motif       5696..5767
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1937_0001"
                     /evalue="1.70E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_1937"
                     /protein_end="27"
                     /protein_start="3"
                     /score="14.3"
                     /tool="antismash"
                     /translation="LLVTGGAGFIGSNFAHWIINNTDA"
     aSDomain        5696..6637
                     /aSDomain="TIGR01181"
                     /aSTool="tigrfam"
                     /description="dTDP_gluc_dehyt: dTDP-glucose
                     4,6-dehydratase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1937_0002"
                     /evalue="3.50E-136"
                     /identifier="TIGR01181"
                     /label="ctg1_1937"
                     /locus_tag="ctg1_1937"
                     /protein_end="317"
                     /protein_start="3"
                     /score="451.4"
                     /tool="antismash"
                     /translation="LLVTGGAGFIGSNFAHWIINNTDATVTVLDAMTYAASEASLEGLP
                     RNRYQLVRGSVCDADLVDELVSHHDAVVHFAAESHNDNSLDGPAPFIQTNIVGTFTLLQ
                     AVRKHEKRLHHISTDEVYGDLQLDDPTKFTPQTRYNPSSPYSASKASSDLLVRAWVRSF
                     GVQATISNCSNNYGPRQHVEKFIPRQITEILEGRRPKLYGSGLNVRDWIHVDDHNSAVW
                     TILERGTIGETYLIGADGELDNKTVIELILELMGQPIDGYDHVNDRPGHDLRYAIDATK
                     LRQELGWQPEYTNFRDGLAATIDWYRGNQSWWL"
     PFAM_domain     5699..6406
                     /aSDomain="Epimerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01370.23"
                     /description="NAD dependent epimerase/dehydratase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1937_0002"
                     /evalue="3.10E-60"
                     /label="ctg1_1937"
                     /locus_tag="ctg1_1937"
                     /protein_end="240"
                     /protein_start="4"
                     /score="203.7"
                     /tool="antismash"
                     /translation="LVTGGAGFIGSNFAHWIINNTDATVTVLDAMTYAASEASLEGLPR
                     NRYQLVRGSVCDADLVDELVSHHDAVVHFAAESHNDNSLDGPAPFIQTNIVGTFTLLQA
                     VRKHEKRLHHISTDEVYGDLQLDDPTKFTPQTRYNPSSPYSASKASSDLLVRAWVRSFG
                     VQATISNCSNNYGPRQHVEKFIPRQITEILEGRRPKLYGSGLNVRDWIHVDDHNSAVWT
                     ILERGTIGETYLIG"
     aSDomain        5702..6223
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1937_NAD_binding_4.1"
                     /evalue="2.50E-15"
                     /label="ctg1_1937_NAD_binding_4.1"
                     /locus_tag="ctg1_1937"
                     /protein_end="179"
                     /protein_start="5"
                     /score="48.1"
                     /tool="antismash"
                     /translation="VTGGAGFIGSNFAHWIINNTDATVTVLDAMTYAASEASLEGLPRN
                     RYQLVRGSVCDADLVDELVSHHDAVVHFAAESHNDNSLDGPAPFIQTNIVGTFTLLQAV
                     RKHEKRLHHISTDEVYGDLQLDDPTKFTPQTRYNPSSPYSASKASSDLLVRAWVRSFGV
                     QATISNCSNNY"
     CDS             6685..8073
                     /NRPS_PKS="Domain: NAD_binding_4 (227-363). E-value:
                     5.7e-12. Score: 37.1. Matches aSDomain:
                     nrpspksdomains_ctg1_1938_NAD_binding_4.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 75.6;
                     E-value: 7.7e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1938"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.8e-31,
                     bitscore: 106.2, seeds: 19, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.3e-65, bitscore:
                     218.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLSIDTTDIPGLLVLHLPLHGDNRGWFKENWQREKMTALGLPD
                     FGPVQNNVSHNAQAGVTRGMHAEPWDKLVSVATGRILGAWVDLRDGNSFGNVVTVEMGP
                     ETAVFVPRGVANGYQALEDGTTYTYLVNDHWSAEAKKSYTFVNLADPALGINWPICVDQ
                     AELSEADRHHPPLSGVIPFRKPRTVVLGSNGQLGKALRPLLPDAEFTTRETLDLSNPAS
                     LGTFDWSGVGTIINAAAYTAVDAAEDPANRATVWAANVSGVAQLVRIAADRRATLVHVS
                     SDYVFDGTKTLHNEDEAFSPLGIYGITKAAADEIVTAYPRHYVLRTSWVVGEGNNFVNT
                     MASLARRGISPQVVSDQHGRLTFTRDLAAAIIHLLTTGAPFGSYNISNEGPTQTWFDIA
                     NEIFTLLGADGTVTPTTAAEWGKGKDLAPRPEHSTLDLSRIEASGFTPATTAHRLREHL
                     GVTK"
     PFAM_domain     6709..7212
                     /aSDomain="dTDP_sugar_isom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00908.19"
                     /description="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1938_0003"
                     /evalue="9.00E-40"
                     /label="ctg1_1938"
                     /locus_tag="ctg1_1938"
                     /protein_end="176"
                     /protein_start="8"
                     /score="136.2"
                     /tool="antismash"
                     /translation="TDIPGLLVLHLPLHGDNRGWFKENWQREKMTALGLPDFGPVQNNV
                     SHNAQAGVTRGMHAEPWDKLVSVATGRILGAWVDLRDGNSFGNVVTVEMGPETAVFVPR
                     GVANGYQALEDGTTYTYLVNDHWSAEAKKSYTFVNLADPALGINWPICVDQAELSEADR
                     HHPPL"
     PFAM_domain     7243..8031
                     /aSDomain="RmlD_sub_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04321.19"
                     /description="RmlD substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1938_0004"
                     /evalue="4.30E-60"
                     /label="ctg1_1938"
                     /locus_tag="ctg1_1938"
                     /protein_end="449"
                     /protein_start="186"
                     /score="203.3"
                     /tool="antismash"
                     /translation="TVVLGSNGQLGKALRPLLPDAEFTTRETLDLSNPASLGTFDWSGV
                     GTIINAAAYTAVDAAEDPANRATVWAANVSGVAQLVRIAADRRATLVHVSSDYVFDGTK
                     TLHNEDEAFSPLGIYGITKAAADEIVTAYPRHYVLRTSWVVGEGNNFVNTMASLARRGI
                     SPQVVSDQHGRLTFTRDLAAAIIHLLTTGAPFGSYNISNEGPTQTWFDIANEIFTLLGA
                     DGTVTPTTAAEWGKGKDLAPRPEHSTLDLSRIEASGFTPAT"
     aSDomain        7366..7773
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1938_NAD_binding_4.1"
                     /evalue="5.70E-12"
                     /label="ctg1_1938_NAD_binding_4.1"
                     /locus_tag="ctg1_1938"
                     /protein_end="363"
                     /protein_start="227"
                     /score="37.1"
                     /tool="antismash"
                     /translation="WSGVGTIINAAAYTAVDAAEDPANRATVWAANVSGVAQLVRIAAD
                     RRATLVHVSSDYVFDGTKTLHNEDEAFSPLGIYGITKAAADEIVTAYPRHYVLRTSWVV
                     GEGNNFVNTMASLARRGISPQVVSDQHGRLTF"
     CDS             8073..8789
                     /locus_tag="ctg1_1939"
                     /transl_table=11
                     /translation="MNLAALGTTVQIDASGTGLDQGELRHAWARCLSAPDPEPVLLAPG
                     PMTASSLTQEITRKLISRQIGRLLMFHAGAVCHPATGDSVVFIAPGGTGKTTLATYLGR
                     RYGYISDETVAIEPDTWRIFPYPKPLSTRRPDLLGEKAEFSPDDLGLQPCHPDPHVSHL
                     VLLARDDSHDTLTTPVRRLDAMVTMAEQSSSLHKLPKPLCLLADLISHAGGVWQAQYAE
                     HDTLGPFIEDLLGAPC"
     CDS             8783..9040
                     /locus_tag="ctg1_1940"
                     /transl_table=11
                     /translation="MLIQRANVTDIWFEDDEALVIVDDAIFRLSPLAVAIWDVLETPLE
                     FDELGRELEALVGPPPDGTLTEALTSFVGTMTLNGILMKT"
     CDS             9069..10004
                     /locus_tag="ctg1_1941"
                     /transl_table=11
                     /translation="MTGVIEGTLRTASRIELTHGVLQRLADRCGADVLHIKGPTVSPEL
                     LEHCIVNDEDTVIPRGSTDADVLVRPEHLAQFETTLAHHGWHKVVDFHDGSAFGHAANY
                     WHELLGYADIHRQFPGINIAPSPAFQALWTRRQGIDIAHTPIHTPSVTDQRLILLLHAA
                     RSGNPNHPDKVRCWDDASDQERQTVRSLARDLDAQVALAAAIGELEQYREHRTYDLWRQ
                     FSTGDPSRLHEWRARVRAAPTRKEAVKVVLNSLALNRPHLRMDLGHDLTRADIVRGYWD
                     RTVRASQEVLQVARKQLRKQLDPRHRRGHR"
     PFAM_domain     9234..9566
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1941_0005"
                     /evalue="2.60E-08"
                     /label="ctg1_1941"
                     /locus_tag="ctg1_1941"
                     /protein_end="166"
                     /protein_start="55"
                     /score="33.8"
                     /tool="antismash"
                     /translation="TVIPRGSTDADVLVRPEHLAQFETTLAHHGWHKVVDFHDGSAFGH
                     AANYWHELLGYADIHRQFPGINIAPSPAFQALWTRRQGIDIAHTPIHTPSVTDQRLILL
                     LHAARSG"
     CDS             10001..10270
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1942"
                     /sec_met_domain="PF05402 (E-value: 3e-10, bitscore: 37.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.7e-08,
                     bitscore: 31.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWRISPNVAWTYDEDGVAVATVPDTQVYRLDSSGGIIWDAVAER
                     PGATTDEIVADVAALIHVPADHICEDVISYLHHLESLGIVIARG"
     PFAM_domain     10070..10255
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1942_0006"
                     /evalue="7.70E-10"
                     /label="ctg1_1942"
                     /locus_tag="ctg1_1942"
                     /protein_end="85"
                     /protein_start="23"
                     /score="39.0"
                     /tool="antismash"
                     /translation="PDTQVYRLDSSGGIIWDAVAERPGATTDEIVADVAALIHVPADHI
                     CEDVISYLHHLESLGIV"
     CDS             10276..10854
                     /locus_tag="ctg1_1943"
                     /transl_table=11
                     /translation="MTEHAQSTAPLRIHFVCTANICRSAYCHARAAHLFNPSRFEVSSS
                     GIQAEEGLPMWEQMRRELERHQAEAAATSSHQIEIDDAVEADLILTMTAGQRDAIVEWW
                     PQVMKRTFTLPQFVAIASELTWDDPTMDPRQVIGKAFQNRFAAGSTDDIEDPYRRSSEI
                     VRACADELDGLLEDLEHMLTPVRPRRAAE"
     PFAM_domain     10312..10788
                     /aSDomain="LMWPc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01451.23"
                     /description="Low molecular weight phosphotyrosine protein
                     phosphatase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1943_0007"
                     /evalue="3.80E-14"
                     /label="ctg1_1943"
                     /locus_tag="ctg1_1943"
                     /protein_end="171"
                     /protein_start="12"
                     /score="53.4"
                     /tool="antismash"
                     /translation="IHFVCTANICRSAYCHARAAHLFNPSRFEVSSSGIQAEEGLPMWE
                     QMRRELERHQAEAAATSSHQIEIDDAVEADLILTMTAGQRDAIVEWWPQVMKRTFTLPQ
                     FVAIASELTWDDPTMDPRQVIGKAFQNRFAAGSTDDIEDPYRRSSEIVRACADEL"
     CDS             10851..11921
                     /locus_tag="ctg1_1944"
                     /transl_table=11
                     /translation="MSTMHLDLGLAQTINRATHVTRGFRRIVMVTATGDNRPNRLVADL
                     TDEFSRRGIEVSQLPIEESKDTTAPSSVPAPARKVLKKWSLHRQEKARQDLGESLDHQS
                     AIIVTDPSRLDEIADLPVAGQADRPVVVLLVTDPDKAPDELPQLVDLVVTPNPDTNPWK
                     HLGVPVHSIGVPAAGASPTPGDRPKRVALLGPCTDEELSEALATFDRACQVVPGWSLEV
                     CLDDETRIHSAVAARRDVGIHPAGSENTIMNQSELALVLTREEDLASRILDAAGAGLPA
                     IAYADTPAAADILSRSGYPATNMEELASALSQGMADAPLRRIQRESAAEVVSGHGSSKI
                     GDAWLDLMFTVGRSRR"
     CDS             12092..12781
                     /locus_tag="ctg1_1945"
                     /transl_table=11
                     /translation="VGFLDKVEKSIEGAVSGVFARAFRGEVEPVEIAGRLQRELDSEAQ
                     ILSRDKSLVPNDFVVRLSSHDYERLVPYTKTLNAEIIPTLRDHASERHYVFNGPIHIRY
                     DLDGSLPVGKFTVLTGENHAKATAGRRAPLVLEVNGVRHPLTPPGLTIGRGSDADIRIN
                     DPGISRLHARVNVWPQGDGIGLSIEDLNSTNGVSVNGVKVSSAEISDGSRIEIGSTRML
                     VHSPTGM"
     PFAM_domain     12101..12442
                     /aSDomain="DUF3662"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12401.10"
                     /description="Protein of unknown function (DUF3662)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1945_0008"
                     /evalue="5.70E-36"
                     /label="ctg1_1945"
                     /locus_tag="ctg1_1945"
                     /protein_end="117"
                     /protein_start="3"
                     /score="123.5"
                     /tool="antismash"
                     /translation="LDKVEKSIEGAVSGVFARAFRGEVEPVEIAGRLQRELDSEAQILS
                     RDKSLVPNDFVVRLSSHDYERLVPYTKTLNAEIIPTLRDHASERHYVFNGPIHIRYDLD
                     GSLPVGKFTV"
     PFAM_domain     12542..12742
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1945_0009"
                     /evalue="1.60E-15"
                     /label="ctg1_1945"
                     /locus_tag="ctg1_1945"
                     /protein_end="217"
                     /protein_start="150"
                     /score="57.3"
                     /tool="antismash"
                     /translation="TIGRGSDADIRINDPGISRLHARVNVWPQGDGIGLSIEDLNSTNG
                     VSVNGVKVSSAEISDGSRIEIG"
     CDS             12784..13272
                     /locus_tag="ctg1_1946"
                     /transl_table=11
                     /translation="VSEFLVTLLRIAYLAVLWIFILLVTNVIRTDIYGHRVPHNAEAAA
                     VGPGRGGKGRKARRREVAPVPTGLQVISGSGAGTYVPLANGVTVGRGNDCTLPIDDDYA
                     STRHAEFSPGIDGTWFVEDLASTNGTHVNGERIENPTRLSVGDEVRIGRTVMTVTGGR"
     PFAM_domain     13042..13239
                     /aSDomain="FHA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00498.28"
                     /description="FHA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1946_0010"
                     /evalue="6.10E-18"
                     /label="ctg1_1946"
                     /locus_tag="ctg1_1946"
                     /protein_end="152"
                     /protein_start="86"
                     /score="65.0"
                     /tool="antismash"
                     /translation="VTVGRGNDCTLPIDDDYASTRHAEFSPGIDGTWFVEDLASTNGTH
                     VNGERIENPTRLSVGDEVRIG"
     CDS             13276..14730
                     /locus_tag="ctg1_1947"
                     /transl_table=11
                     /translation="MAFSLDVRCHSEIGLVRRNNQDSGYVSPRMLVVADGMGGAAAGDL
                     ASTVAVRHVARADERFSGEDSPCRPQGEEMLTVLAGAVADANDELADLVAWDSSLEGMG
                     TTFCGAMFSGTQLGVVHIGDSRGYLLRQGRMKRMTHDHSWVQSLIDDGRITPEEAAVHP
                     HRSLLLKVLNGQPQHVPDTQIVDLRLGDRILFCSDGLCGLVDDETIAEHLSTTNLDDVV
                     DLLATDAHAGGGTDNITIVVAEVVGADPVLDASEPHIIGAATTRKVPEHEVTAPLSVEQ
                     PSSATKDAGTSTVLFDSEAEESMRYAPVDSRTRRRRHWLWPVVVLAVAAVVVGGIFGTR
                     AYLNTQYYVGTDGNAVAIYQGSPDSLAWIQLSHVAETTDVKTTDLPRYYRNRVSENIRV
                     SSMESAHSTVAELRTGAEHCKAVREMATTPPAAPTRPSTTLSASPQSSASSSGIPHPSA
                     VPTPAMPSPSASGHEVDLPAVSSGDC"
     PFAM_domain     13333..13920
                     /aSDomain="PP2C_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13672.8"
                     /description="Protein phosphatase 2C"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1947_0011"
                     /evalue="9.70E-11"
                     /label="ctg1_1947"
                     /locus_tag="ctg1_1947"
                     /protein_end="215"
                     /protein_start="19"
                     /score="41.8"
                     /tool="antismash"
                     /translation="NQDSGYVSPRMLVVADGMGGAAAGDLASTVAVRHVARADERFSGE
                     DSPCRPQGEEMLTVLAGAVADANDELADLVAWDSSLEGMGTTFCGAMFSGTQLGVVHIG
                     DSRGYLLRQGRMKRMTHDHSWVQSLIDDGRITPEEAAVHPHRSLLLKVLNGQPQHVPDT
                     QIVDLRLGDRILFCSDGLCGLVDDETIAEHLST"
     CDS             14730..16136
                     /locus_tag="ctg1_1948"
                     /transl_table=11
                     /translation="MSVVPEFDDGTVVVQSKRRWTELFMLLIAWAIGFGGWVLTELNIN
                     HELPETWMTVGGVWLGMAVIAHIFVRIVIPYADPVILPIVFTLNGLGLAMIHRIDLVPD
                     PNKNRMDTQAMWTALGLILFLTTLLVLRDHRKLQKYPYVLFIVGLGFLLLPLVPGLGMS
                     VLGSRVWIRIGSYSFQPAEVSKVVLAIAFAAYLVDNRDVLSRAGHRILGITLLRARDLG
                     PIAVMWVATMLVIVYQNDLGTGMLFYGMFVVMLYLTTERVGWAILGAVSLVGGAALAYA
                     FFGHVRIRFDSWLHPFTDYSQNYQIIQAQFGLAWGGLAGRGWGLGRPGMVPLAWSDFIA
                     TSIGEELGVTGLMAVIMMFFILTARGMRTALGCRDEFGKLMVAGLSFTLALQVFAIIGG
                     VTRLLPLTGLTTPFMSQGGSSLVANWVIVAIIMIVSHRNRKPADDFTATVPVDPQAQEA
                     TTVIPNGGTR"
     PFAM_domain     14973..16046
                     /aSDomain="FTSW_RODA_SPOVE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01098.21"
                     /description="Cell cycle protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1948_0012"
                     /evalue="5.20E-77"
                     /label="ctg1_1948"
                     /locus_tag="ctg1_1948"
                     /protein_end="439"
                     /protein_start="81"
                     /score="259.4"
                     /tool="antismash"
                     /translation="LPIVFTLNGLGLAMIHRIDLVPDPNKNRMDTQAMWTALGLILFLT
                     TLLVLRDHRKLQKYPYVLFIVGLGFLLLPLVPGLGMSVLGSRVWIRIGSYSFQPAEVSK
                     VVLAIAFAAYLVDNRDVLSRAGHRILGITLLRARDLGPIAVMWVATMLVIVYQNDLGTG
                     MLFYGMFVVMLYLTTERVGWAILGAVSLVGGAALAYAFFGHVRIRFDSWLHPFTDYSQN
                     YQIIQAQFGLAWGGLAGRGWGLGRPGMVPLAWSDFIATSIGEELGVTGLMAVIMMFFIL
                     TARGMRTALGCRDEFGKLMVAGLSFTLALQVFAIIGGVTRLLPLTGLTTPFMSQGGSSL
                     VANWVIVAIIMIVSHRNR"
     CDS             16133..17560
                     /locus_tag="ctg1_1949"
                     /transl_table=11
                     /translation="MNKQIRGVSLLAGLMFMALMVNLTGSAIFRQAGLNNDPRNVRVRD
                     AEFSQNRGDILVGSMPIATTKSRDGKFAYQRVYPSGPEYAPITGYYSYYYGRSMLEQTQ
                     NAQLTGTSDAQWLSRITGTLSGHKPEGGSITTTVNAKAQDAAWEGLRGKKGAVVAMDYT
                     TGAVLAMASSPSYDPNDLASQRLNDTSQAWKELVADKSSPLSNRASREIYPPGSTFKLV
                     TAAAALQNGYNPNSTVDAPENWILPGTRTPLTNETYCGGKQITLTRALDISCNTAFGKL
                     GVGLGQDKINAQAEEFGFGKVVDSDISSVASKFPKDMTDAQLAQSSIGQFDVAASPLQM
                     AMVTAGIANGGKLMTPYLTAQVRASNLQVVSEHRPKQMSQPMTKESAEQLKSMMVSVVN
                     NGTGKRARIDGVTVGGKTGTAQTMRGKAPYAWFVGWSDKPHVAVAAFIQSSNTDIDEIS
                     GGRLAAPIARDVIEAMR"
     PFAM_domain     16595..17548
                     /aSDomain="Transpeptidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00905.24"
                     /description="Penicillin binding protein transpeptidase
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1949_0013"
                     /evalue="1.40E-70"
                     /label="ctg1_1949"
                     /locus_tag="ctg1_1949"
                     /protein_end="472"
                     /protein_start="154"
                     /score="238.0"
                     /tool="antismash"
                     /translation="GAVVAMDYTTGAVLAMASSPSYDPNDLASQRLNDTSQAWKELVAD
                     KSSPLSNRASREIYPPGSTFKLVTAAAALQNGYNPNSTVDAPENWILPGTRTPLTNETY
                     CGGKQITLTRALDISCNTAFGKLGVGLGQDKINAQAEEFGFGKVVDSDISSVASKFPKD
                     MTDAQLAQSSIGQFDVAASPLQMAMVTAGIANGGKLMTPYLTAQVRASNLQVVSEHRPK
                     QMSQPMTKESAEQLKSMMVSVVNNGTGKRARIDGVTVGGKTGTAQTMRGKAPYAWFVGW
                     SDKPHVAVAAFIQSSNTDIDEISGGRLAAPIARDVIE"
     CDS             17618..19498
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 283.8;
                     E-value: 2.2e-86)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1950"
                     /sec_met_domain="Pkinase (E-value: 8.6e-53, bitscore:
                     176.4, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTESWLSGRYELQNLIGRGGMADVWRARDHRLGRDVAVKRLRAD
                     LASDDTFQARFQREAQSAARLNHPNIVAVYDTGETQDPTTGLQVPYIVMELIDGHTLRD
                     VLRDGRKILPRRALEFTQGVLDALSYSHAAGIVHRDIKPANVMLTREGYVKVMDFGIAR
                     AVADTSATMTQTAAVIGTAQYLSPEQARGETVDNRADIYATGCLLYELLVGRPPFIGDS
                     PVSVAYQHVREIPAPPSSLDSEITGEMDAITLKALAKERADRYQTAKQMRDDIDRLLSG
                     REPLAMQAHADPDADTEEQTHLIPAAAATAAAPPAAPAAAAQRDEATPAQTESPAEPEE
                     PKRKRWPVVLVTILVVALLALLGFGLHRMLGPSSAPTSSPTPSKTVKMVDVPAVTGLSQ
                     QGATSTLENAGLKVKVEHVQKDESTANQVVSQNPAANQKVPEGSKVTITVNDGPKKLTI
                     PQNIVGMPKSDAVKALKDAGFSDNQIRVNDDDPKTEANTAKAGTVDSVRPSAGTSLTPE
                     QQVTLTVATGKSVVPNLKGMSVEEAYAAASSNGFSISVERQTTSSAAPGTVFSQDPDYG
                     ATAKRSTAIKVLVAVKPSEPTHEAPTSPTPSEDDPSPVPTSTASPSSSHG"
     PFAM_domain     17648..18415
                     /aSDomain="Pkinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00069.27"
                     /description="Protein kinase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1950_0014"
                     /evalue="2.50E-49"
                     /label="ctg1_1950"
                     /locus_tag="ctg1_1950"
                     /protein_end="266"
                     /protein_start="10"
                     /score="168.2"
                     /tool="antismash"
                     /translation="YELQNLIGRGGMADVWRARDHRLGRDVAVKRLRADLASDDTFQAR
                     FQREAQSAARLNHPNIVAVYDTGETQDPTTGLQVPYIVMELIDGHTLRDVLRDGRKILP
                     RRALEFTQGVLDALSYSHAAGIVHRDIKPANVMLTREGYVKVMDFGIARAVADTSATMT
                     QTAAVIGTAQYLSPEQARGETVDNRADIYATGCLLYELLVGRPPFIGDSPVSVAYQHVR
                     EIPAPPSSLDSEITGEMDAITLKALAKERADRYQ"
     PFAM_domain     18782..18967
                     /aSDomain="PASTA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03793.21"
                     /description="PASTA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1950_0015"
                     /evalue="8.80E-14"
                     /label="ctg1_1950"
                     /locus_tag="ctg1_1950"
                     /protein_end="450"
                     /protein_start="388"
                     /score="51.2"
                     /tool="antismash"
                     /translation="VDVPAVTGLSQQGATSTLENAGLKVKVEHVQKDESTANQVVSQNP
                     AANQKVPEGSKVTITVN"
     PFAM_domain     18998..19192
                     /aSDomain="PASTA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03793.21"
                     /description="PASTA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1950_0016"
                     /evalue="3.00E-10"
                     /label="ctg1_1950"
                     /locus_tag="ctg1_1950"
                     /protein_end="525"
                     /protein_start="460"
                     /score="39.9"
                     /tool="antismash"
                     /translation="NIVGMPKSDAVKALKDAGFSDNQIRVNDDDPKTEANTAKAGTVDS
                     VRPSAGTSLTPEQQVTLTVA"
     PFAM_domain     19205..19384
                     /aSDomain="PASTA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03793.21"
                     /description="PASTA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1950_0017"
                     /evalue="7.60E-14"
                     /label="ctg1_1950"
                     /locus_tag="ctg1_1950"
                     /protein_end="589"
                     /protein_start="529"
                     /score="51.4"
                     /tool="antismash"
                     /translation="VVPNLKGMSVEEAYAAASSNGFSISVERQTTSSAAPGTVFSQDPD
                     YGATAKRSTAIKVLV"
     CDS             complement(19500..20129)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 130.5; E-value: 1.2e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1951"
                     /transl_table=11
                     /translation="MTARILVVDNYDSFVWNLVSYLGQIGADTTVVRNDDPLFEDPQWW
                     DPFDGILLSPGPGHPEDAGVCVDILRGARRPIFGVCLGMQAMAIAWGGHVGRAEEQLHG
                     KTSPIHHEGKGVFAGLPDPLVVTRYHSLAVDEIPAELEVTARTDTGVVMGLRHRRLPVE
                     GVQFHPESVLSQHGHQMLATWLMECGDPEAPSRASQMSPLMSAADR"
     PFAM_domain     complement(19572..20111)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1951_0018"
                     /evalue="4.70E-53"
                     /label="ctg1_1951"
                     /locus_tag="ctg1_1951"
                     /protein_end="186"
                     /protein_start="6"
                     /score="179.9"
                     /tool="antismash"
                     /translation="VVDNYDSFVWNLVSYLGQIGADTTVVRNDDPLFEDPQWWDPFDGI
                     LLSPGPGHPEDAGVCVDILRGARRPIFGVCLGMQAMAIAWGGHVGRAEEQLHGKTSPIH
                     HEGKGVFAGLPDPLVVTRYHSLAVDEIPAELEVTARTDTGVVMGLRHRRLPVEGVQFHP
                     ESVLSQHGHQMLATWLM"
     aSDomain        complement(19575..20117)
                     /aSDomain="TIGR00566"
                     /aSTool="tigrfam"
                     /description="trpG_papA: glutamine amidotransferase of
                     anthranilate synthase or aminodeoxychorismate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1951_0003"
                     /evalue="3.00E-59"
                     /identifier="TIGR00566"
                     /label="ctg1_1951"
                     /locus_tag="ctg1_1951"
                     /protein_end="185"
                     /protein_start="4"
                     /score="198.0"
                     /tool="antismash"
                     /translation="ILVVDNYDSFVWNLVSYLGQIGADTTVVRNDDPLFEDPQWWDPFD
                     GILLSPGPGHPEDAGVCVDILRGARRPIFGVCLGMQAMAIAWGGHVGRAEEQLHGKTSP
                     IHHEGKGVFAGLPDPLVVTRYHSLAVDEIPAELEVTARTDTGVVMGLRHRRLPVEGVQF
                     HPESVLSQHGHQMLATWL"
ORIGIN
        1 cctgttccag acgcttggcc accaaggaca cctgatcgcg gtgagtcttc ccaaccacgg
       61 ctacatagat cgtgccgtcc gctatcgtgc cgagcaggcc agcatccgtg acggccagta
      121 acggcggagc gtcgatgaca acaaaatagc ctcgcctgcg caactcggct agcagatcct
      181 tcattcgctg ggagccaagc agctcggacg ggttcggcgg gatacgcccc gcggccaaca
      241 tctggagacg cttggtctcg gttcgcatca gtgcgtcatc gaggctcacg tcgccggcaa
      301 gtacctgcga gagcccgacg cccgcttcgg tgccaaaggc cttgtgctgc accggacggc
      361 gcatgtcggc atcaatgagg acaaccttct cgccagcttg agccattacc accgcgaggt
      421 gagtcgaaac cgtcgactta ccttctcccg gatttgcgga ggtgatgacg accgaacgag
      481 gagggttgtc aacattggca aacctcaggt tcgtacgaag ttggcggaac gcttcaccag
      541 tcacgccgga aatatggaca atcgacctct cacgctgttc cgcaagcttc ttgtcatctg
      601 gtacgacggc aagagttccc gaacccgtaa gctcttcgac cgtcgcctgg tccctgaccc
      661 tgacgtcgaa ctgcttccga acaactgcta tgaccgcacc gatgaggaac ccaatcacca
      721 aaccagcggc aaggaataat gccagcgact tcccacggtc accggttgga aggccggcgg
      781 actcatagcc gagaacatgc accgaggtca tcttggccaa ctgggcatcg ctcttgttgc
      841 ctgacccggc agtctggcca taggtctcca ttcgcagggc ctcggaaatg agcgcctcca
      901 gccccgcatt ggcaagggcc tgagcattct tggcagtgcc gccagtcgct ttgatctcga
      961 taaaggcagt gtcacttggg gcggatgctg tcagctggcc actcgcagcc tctgacatcc
     1021 cctgtttctt gaggatctcg gctgtctttt gagccatggt tcgcgtctcg acgagcttcg
     1081 tgtaggtcgt tgcgcgctgc tgggcgatcg tgttgcccga catggccccg ccgacggagg
     1141 cggagtcacc ggccaccacc atgcctgtcg ctttggccgt aaacacctct gggcgggtca
     1201 actgatatgc cgcgccgatc aacccgccta tcacggtgca gatgatcaac agggcaagat
     1261 tgcgccgcag aatgcggact acgtcaacga ctgtcacggg gattgaactc ctctaattct
     1321 gggactgcag gcgctgtgat gcctctcaaa cggcaaagga cagcctacgg cctggcgtag
     1381 gcatcgagcg agttgggagc aaggcccctt gtcacaaggc cccggcgtgc tgaacagctt
     1441 gctccgcagt ctccgtacag ccaagaacgg cacgctcctc gccttcagca ccgggaacat
     1501 ggcaaccgtc attttccctc caccaagatc gaggtcgtcc acgccaatgg ctggttcaag
     1561 tctcccgccc tcgcagcatc cactttttca cggaattggt cgagccgatg accgaaggca
     1621 ctcgtcagga gaatctcctt cgaaacctcg ctgggacggc cgccgccttg agccacctta
     1681 cgaggcgcga gagatgcact caccacagtg gcacacaagc caatggtcag taggaggcag
     1741 agaaccttcc gaacgatccc ttcggcgcgt tcgacgcgtg tccccaccat gtccggccac
     1801 atcagaatca agacgacaat caaggtgggc acgactctct cccctggatt gacgatgccc
     1861 aagaagtagg gcggaaagat ggctgcgatc gctccgaggc tgacgagcgc gagaagctgc
     1921 cacctggagg ttcgccacag cgtgctccaa ctcaccagcg acaggacgac cagtacgaca
     1981 aggagaacag cgaacaggaa gttcaggatg gcaccgccgt agaacaacca cggggcgatc
     2041 tgatgatccc cgaccgatga cgcgatgatg ttctgatacc cccctgattt cgccagcgta
     2101 tagccccggt actcgatgaa gtgcgtgacg gactcgtagc cagtctcccg ccccttcgcc
     2161 tcgttggact tcaggaagta ccacaacacg agtgccatgg ccgggacgac cccgacgatg
     2221 agatcgcgga ttctccggga agtaagggct cggacaccgg ctacgagccc ccagcacccg
     2281 aagatgatgc cgtgggtgaa gaaggtggcc agagcgaagg ccatgacgac aggccatcga
     2341 gtggcattac ggtcgctcac cgcgaggtag ccgacaatga tgaccatccc ccagtacaaa
     2401 cccacgtagc cgttccagta ctgtgagccg ccgagcacac agatcgcaag gacgcaggcc
     2461 gtcatcaccg gtggcagcgc gcgccggacg accagcagat cggacaccca cgctgctgcc
     2521 gccgcgtgaa tgaacaggaa cacagtcgag ccgcccacgg ccccgaagat caactcacac
     2581 agcgacagca atgcctgcgg aaggaagtaa ggcaccgggt aggtgatgag ggtcccaaca
     2641 tgcggctctt caccggcaag gatgccagcc acgacacgcg cttggtagat ccactcccca
     2701 aagtcctgga atgccgggaa gcccatcgaa cacgtgacca ccaggaactg gacacagaac
     2761 actacaaaca ccatggctcc agccacgtgt ctgccaagaa aacgcttcat caaagacctt
     2821 tcggggaaca tgctcgctga acgggatgag ctagggagct gaaggaccgg cgacactcgt
     2881 cggatcggaa accccctggg cttgatttca gctggtcaac aggccacgca ggtaagcacc
     2941 atatccagat ttctcgaact gccccgccct ggcgaggaga tcatcgtctg acaggaaccc
     3001 acaacgccat gcagcctctt ctgggcagcc cacctgaaga ccctgcctgg cttgaatggc
     3061 acgcacgaag ttcccggcat cgttgaggga gtcgaacgtc ccggtatcca accaggcggt
     3121 gccgcgcggc agaagctcga catgcagacg tcgctgttcc atgtaggtcc gattgacgtc
     3181 ggtgatctcc agttcaccac gcgccgaggg tctgagacca cgagcgacct caacgacatc
     3241 gttgtcatag aaataaagcc caggcaccgc ccaatgtgac ttcggatgct ccggcttctc
     3301 ctcaatcgac agtgcgaacc catcatcgtc aatctcgacg acgccgtaag cgctcggatc
     3361 ggcaacccgg tagccaaaga cgagggctcc gtccactgat tgagccttgg cctggaggcg
     3421 agttcccaac cccggccctg agaagatgtt gtcccccaga atgaggcacg atgaatcact
     3481 cccgatgaat tcggccccga tggtgaacgc ctgagcgaga cccttgggtt cgggctgcac
     3541 tgcgaactcg atggatattc caaactggga accatcgccg agcaagtggc gaaaggcctc
     3601 ggcctcatga ggggtggtga tgaccaagac atcccggatg ccggcaaaga tcaaggtcgt
     3661 cagtgggtag tagatcatcg gcttgtcgta gacaggcatg agctgtttac tcgtccccag
     3721 agtgatcggg tggagtcggg agccagtacc accggccaag atgatgcctc gcatgccccc
     3781 catcatgcca gacatgatga acacgacacg gcgcaggtta caccggctgt acgttctttc
     3841 cgggcatcat cgacatgagc aaccggatga acgcgacacc gtcagagcac aaaccgaaca
     3901 actgcgtgag ggagctgttc acactgtggc cggcacgctt catgtggacc atgtgcacgt
     3961 gctatattct ggccaattct accgtagcta ccgacagacc cccgtaactc tcggcagaac
     4021 ctttgccact tctcaaggag cagacatgga cagcaaaaac aggcaagccc acgcaactgg
     4081 gccatcgcaa gtatcgcgtc ggtcagtggc caagggcact gcttgggcag tgtcggcgat
     4141 taccagcatg actctggtgc ctctggtgcc agcctttgcg gccagcgcgc agcgcaagca
     4201 ggtcaccatc accttcgacg caaagaaaca caaagagacc atccagtgcg tacggatacc
     4261 agccgaagcc accgacatcc gctattccat ccgcggcgga gcgggcggcg caggccccaa
     4321 ggacagctgg ggcgaacggg gcggatccgg tgccgaagta ctaggtcaga tccatcggcc
     4381 cggcgagggt acggccgccg cacaggagtt caccatctgg ggtgtggccg gtggctacgg
     4441 gcccacggcc gcatggaacg ataatgccgt cgagttcgca accggctacg gcaacggcgg
     4501 cccgtcaatg ggtgtgccct accacaccag tatcgtctca actgagcaat ggtctgaacg
     4561 ttggtgccac ggtggcggcg ccggttcggc aatagccatc ggcggtgacc ccgaggggcc
     4621 aggccagctc gtggcggtgg ccggcggcgg cggagccgcc ggtacaggca cgtattcgcg
     4681 ggaggcggcg aatatgggcc ccaacgtctg gcccgtccga gagggtggca acggaggcaa
     4741 cggaggcaag agctgggacg gcgccgatgg cggccagtcc cactacgaga cgaaatatgc
     4801 ccaggtcact gcagccggcg gctcgggagc ccgtggcggt cagggcggca acggaggtag
     4861 cacggcaaat acctcgtacg tccccaaaga cctcgagttc gacaagatca ttgcgggcca
     4921 ggccggcggc aaccacggca gcggcaacca cggtggtggc gacgggggtg cgcctgtcaa
     4981 gttcgagcgc aggcgtagcg tcagggggga cggtcacatt gatgactaca tcgcgctgtc
     5041 ctcggctgcg ggtggcggcg gctacgccgg cggtggttcc ggggcactcg tcgtcatttc
     5101 acgcgatccg atcttgaagt gggcggccag cgacgtccct ggacagttgg gggccattgg
     5161 tgccggcggc gctggcagca gctacctcgc acccagcctg gacggtggtt tcagcgcgac
     5221 cggggagatc gacttccccg acactggtgg cgtgcgcacc aatggcacag tgcacatggc
     5281 acccagtctg ccgaagaact acggcaagcc cggaaacgtc acgatcagtt tctgggtccc
     5341 cgaggacatg tcttcaaaac ccagtgacta caccgacaag tgctgaggca ttctcggatg
     5401 ccctcgtgac agggagggga aggtgaatct gattcacctt cccctccctg atctttgagg
     5461 gattgaccaa cgactgacac ctgctcacga cacaaaggac agtcagcgag cgaatgtcaa
     5521 gcacctcgtg gcgggatggc gatgttggct ctcacgtgcc gggccaccaa cgggggacgt
     5581 ggtactgcat gaagacggtt tgatgtgagg acggttccgc cgcgaaacca tgccgcccca
     5641 gccacgggtg aagccatcaa gcattgcttc ctctacactg cctgttatgc actcccttct
     5701 cgtcactggc ggagccggat tcatcggcag caactttgcc cactggatca tcaacaacac
     5761 tgacgccaca gtgacggtgt tggacgccat gacgtatgcc gccagtgagg cctccctgga
     5821 aggactgccg cgcaaccgat atcagctagt acgcggatcg gtgtgtgatg ctgatctcgt
     5881 cgacgagctc gtctcccatc acgacgccgt cgtccacttc gccgctgaat cccacaatga
     5941 caattccttg gacggcccgg ccccgttcat ccaaaccaac atcgtcggca ccttcaccct
     6001 gttacaagcc gtccgcaaac acgaaaagcg gctacaccac atttccactg acgaggtcta
     6061 tggcgatctt caactcgacg accccaccaa gttcacccca caaactcgat acaacccgtc
     6121 gtcgccctac tcagcttcca aagcctcctc ggaccttctg gtacgtgctt gggtacgctc
     6181 attcggagtc caagccacca tctcgaactg ctcgaacaac tatggcccac gccagcacgt
     6241 cgagaagttc atcccccgtc agatcaccga aatccttgag ggacgacgcc ccaagctcta
     6301 cggcagcggt ctcaatgttc gcgactggat ccacgtcgac gaccacaact cggccgtgtg
     6361 gacgatcctc gaacgcggca cgatcggcga aacgtacctc atcggagccg acggtgaact
     6421 cgacaacaaa accgtcatcg aactcatcct tgaactcatg ggccagccca tcgacggcta
     6481 cgaccacgtc aacgaccgcc ccggccacga cctgcgctac gccatcgacg ccaccaagct
     6541 gcgccaggaa ctcggctggc agcccgagta cacgaacttc cgcgacggcc tggcagcgac
     6601 catcgactgg taccgcggca atcagtcgtg gtggctcccc cagaaggaga ccaccgaggc
     6661 cgcctacgcc gcgaaagggc agtgatgagt gacctgagca tcgacaccac cgacatcccg
     6721 ggccttctcg tcctgcacct gcccctgcac ggtgacaacc gcggctggtt caaggagaac
     6781 tggcaacgcg agaagatgac cgctctcggc ctacctgatt tcggaccagt acaaaacaac
     6841 gtgtcgcaca acgcccaggc aggcgtcacc cgaggcatgc acgcagaacc gtgggacaag
     6901 ctcgtctcgg tggcaactgg gcgcatcctc ggcgcctggg tggatctacg tgacgggaac
     6961 tccttcggca acgtcgtcac cgtcgagatg ggtccggaaa ccgccgtgtt cgtcccccgg
     7021 ggcgtcgcca acggctacca ggccctcgag gacggcacga cctacaccta cctcgtcaac
     7081 gaccactggt cggccgaagc caagaagtcc tacaccttcg tcaacctcgc cgatccggcg
     7141 ttgggcatca attggccgat ctgcgtggac caggccgagc tgtccgaggc tgaccgtcat
     7201 cacccaccgc tgagcggggt catccccttc cgtaagccgc gcaccgtcgt gctgggatcc
     7261 aacggccagc tcggcaaggc actgcgccca ctcctgcccg acgccgagtt caccacccga
     7321 gagaccctcg acctgtccaa cccggccagc ctaggcacct tcgactggag tggggtcggc
     7381 accatcatca acgccgccgc ctacaccgcc gttgacgccg ccgaagaccc ggccaaccgt
     7441 gccacagtct gggccgccaa cgtctccggc gtcgcccaac tcgtccggat tgccgctgac
     7501 cgacgcgcca ccttggtcca cgtctccagt gactacgtct tcgacggcac caaaaccctc
     7561 cacaacgagg acgaggcgtt cagcccgctg ggcatctacg gcatcaccaa ggccgccgcc
     7621 gacgagatcg tcaccgcgta cccccgccac tacgtgctac gcaccagctg ggtcgtcggc
     7681 gaaggcaaca acttcgtcaa caccatggcc agtctggccc gtcgcggcat cagtcctcag
     7741 gtcgtctccg atcagcacgg tcgtctcacc ttcacccgtg accttgccgc cgcaatcatc
     7801 cacctgctga cgaccggggc acccttcggc agctacaaca tctccaacga gggaccgacg
     7861 cagacctggt tcgacatcgc gaacgagatc ttcaccctgc tgggagccga cggcaccgtc
     7921 accccgacga ccgccgccga atggggcaag ggcaaggact tggcaccgcg tcccgagcat
     7981 tccaccctcg acctgtcccg catcgaggcc agcgggttca ccccggccac gactgctcat
     8041 cggctgcgcg agcacctggg cgtgaccaag tgatgaattt ggcagccctc ggcaccacgg
     8101 tgcagatcga cgcatccggg accgggctgg accaggggga gctccgccac gcgtgggcac
     8161 gttgcctcag cgccccggat cccgaaccgg tcctgctcgc ccccggaccg atgacggcat
     8221 cctccctgac ccaagagatc acccggaaac tcatctcacg tcagattggc cgcctcctca
     8281 tgtttcacgc cggcgcggtg tgtcacccag ccactgggga ctcagttgtc ttcatcgccc
     8341 ctggcggcac cgggaaaacc acccttgcca cgtacctggg gcgacgatat ggatacatca
     8401 gcgacgaaac ggttgccatc gagcccgaca cctggcggat cttcccttac cccaaaccgc
     8461 tgtctacccg tcgtcccgac ctcttggggg agaaggcaga attcagcccc gacgacctgg
     8521 gactgcagcc ctgccacccc gacccccacg tcagccacct cgtgctcctg gcacgagacg
     8581 attcccacga cactctcacc acccccgtgc ggcgtcttga cgccatggtg acgatggccg
     8641 aacagtcctc gtccctccac aaactcccca aaccactgtg cctgctggcc gatctcatct
     8701 cgcacgccgg aggggtctgg caagcccaat acgcggagca cgacaccctc ggaccattca
     8761 ttgaggacct tttgggggca ccatgctgat tcagcgtgcc aacgtcacag acatctggtt
     8821 cgaggacgac gaggcactcg tcatcgtcga tgatgccatt ttccggctct cccccctcgc
     8881 cgtcgcgata tgggacgttc tcgagacccc actcgaattc gacgagttgg gtcgcgaact
     8941 cgaggccctt gtcgggccac cgcccgacgg tacattgacc gaggcgctca cgagtttcgt
     9001 cggcaccatg accctcaacg ggatattgat gaaaacatga cgccacttca ttgataagct
     9061 ccagagcgat gactggcgta atcgagggga cacttcgcac cgcgagtcgc atcgagctga
     9121 cacatggcgt cctacaacgg ctggccgacc gatgcggcgc cgacgtgcta cacatcaaag
     9181 gccccactgt ctccccagaa cttctggagc actgcatcgt caatgacgag gacaccgtca
     9241 tcccacgcgg ctccacggac gcagacgtcc tcgtgcgtcc tgagcacctc gcccagttcg
     9301 agaccacact cgcacatcac ggctggcaca aagtggttga cttccatgac ggctcggcct
     9361 tcggtcatgc ggccaattat tggcacgaac tccttggcta cgccgacatc caccgtcaat
     9421 tccctggcat caacatcgcg ccctcaccgg cattccaagc cctgtggacc cgtcgtcaag
     9481 gaatcgacat cgcccacacc cccatccaca ctcccagcgt caccgaccag cgtctcatcc
     9541 tcctgctgca tgccgcccgc agtggcaacc cgaaccatcc cgacaaggtg cggtgctggg
     9601 acgacgccag cgatcaggag cgccagacgg tgcgcagcct ggcccgcgat ctcgacgccc
     9661 aggtcgccct ggccgccgcc atcggcgaac tggagcagta ccgcgaacac cgcacctatg
     9721 acctgtggcg acagttctcg accggcgacc ccagtcgtct gcacgagtgg cgcgctcgag
     9781 tccgcgccgc tcccacccgc aaggaagccg tcaaggtagt tctgaattcc ctcgctctca
     9841 atcgaccgca cctccgcatg gacctcggcc atgacctcac ccgcgccgac atcgttcgcg
     9901 gctactggga ccgcaccgtc agggcctccc aggaggtcct ccaggtggcc cggaaacagc
     9961 tcaggaagca gctggacccc cgacaccgga ggggacaccg atgacgtggc ggatcagccc
    10021 caacgtggcc tggacgtacg acgaggatgg cgtggctgtg gctaccgtcc cggatactca
    10081 ggtgtatcgc ctcgacagca gcggcggaat catctgggac gccgtcgccg agcgcccggg
    10141 agcgacgacc gacgagatcg tcgcggacgt tgccgccctg attcacgtgc ctgccgacca
    10201 tatctgtgag gacgtcatca gctacctcca ccacctggaa tcactcggta tcgtgatcgc
    10261 gagaggttga cgatcatgac cgaacacgca cagtcgacgg ccccgctgcg aatccatttc
    10321 gtctgcacgg ccaatatctg ccgctcggcg tattgccatg cccgggcagc tcacctgttc
    10381 aatccctcgc gcttcgaggt ctccagctca ggcatccagg ccgaggaagg cctgccgatg
    10441 tgggagcaga tgcgccgcga gctagaacgc catcaagccg aggcggccgc gacctcctcc
    10501 caccagatcg agatcgacga cgcggtggaa gccgacctca tattgacgat gacggccgga
    10561 caacgggacg ccatcgtcga atggtggccg caagtgatga aacggacctt caccctgccg
    10621 caattcgtcg caatcgccag tgagctcacc tgggacgatc ccactatgga ccctcgacag
    10681 gtcattggca aggcatttca gaaccgtttc gcggctggct cgacggacga catcgaggac
    10741 ccctaccgtc gcagcagcga gatcgtacgg gcctgcgccg acgaattgga cggacttctc
    10801 gaggatctag aacacatgct gacccccgtg aggccccgtc gcgcggcaga atgagcacca
    10861 tgcacctcga tctcggcctc gcccagacca tcaaccgcgc aacccacgtc acccgcggat
    10921 tccgccgcat cgtcatggtg accgccaccg gggacaaccg tcccaatcgc ctcgtcgccg
    10981 atctcaccga cgagttctcc cgccgtggaa tcgaggtgtc acagcttccg atcgaagaat
    11041 ccaaggacac cacggccccc tcgtcggtgc cagccccggc ccgcaaggtc ctgaaaaagt
    11101 ggtcactcca ccgtcaggag aaggctcgcc aggacctcgg cgagagcctc gaccaccagt
    11161 ccgcgatcat cgtgaccgat cccagccgtc tcgacgagat cgctgatctc ccggtcgctg
    11221 gtcaggccga ccgtccggtc gtcgtcctgc tcgtcaccga ccccgacaag gctcctgatg
    11281 agctccccca gctcgtcgac ctcgtcgtca ccccgaaccc cgacaccaat ccctggaagc
    11341 acctcggtgt tccggtgcac tccatcggtg tgccggccgc aggcgccagc ccgacccctg
    11401 gtgaccgtcc gaagcgagtc gccctgctcg gcccatgcac cgatgaggag ctctcggaag
    11461 ccctcgccac cttcgaccga gcctgccagg tcgtccccgg ctggtccctg gaggtatgcc
    11521 tcgacgacga gacccgcatc cactccgcag tggcagcccg ccgtgacgtc ggaatccacc
    11581 cggccggatc tgagaacacc atcatgaacc agagtgagtt ggccctggtc ctgacccgcg
    11641 aggaggacct agcctcccgg atcctcgacg ccgctggtgc cggactgccc gccatcgcct
    11701 acgccgacac ccctgcggca gctgacatcc tctctcgcag cgggtatccg gccacgaaca
    11761 tggaggaact ggccagcgct ctctcccagg gcatggctga tgccccgctg cgtcgtatcc
    11821 agcgcgagtc tgcggccgag gtcgtctccg gccatggcag ctcgaagatc ggcgacgcat
    11881 ggctcgacct catgttcacc gtggggcgca gccgccgctg accttcccac cggccccggt
    11941 ggcgcttccg aagccgcttt cgagtgcaac gtccgccacg cggaacacgg ccgtcacagg
    12001 gtatcgtcag accttctggg tacactcgca tggtggtagt ccgtgtgaaa cggacgacca
    12061 gcctgacatg tcagccggaa ggaggagccg ggtgggtttc ctggacaagg tcgagaagtc
    12121 gatcgaaggc gccgtcagtg gcgtcttcgc gcgcgccttc cgtggtgagg ttgagccggt
    12181 ggagatcgcc ggtcggctgc agcgcgagct cgactccgag gcgcagatcc tgtcccgcga
    12241 caagtcactg gttcccaatg atttcgtggt ccggctgtcc agccatgatt acgagcgtct
    12301 cgtcccctac accaagaccc tcaatgccga gatcatcccg actctgcgtg atcacgccag
    12361 cgagcgtcac tacgtgttca acggacccat ccacatccgt tacgacctgg acggctccct
    12421 gccggtcggc aaattcaccg ttctgacggg cgagaaccac gccaaggcca ccgctggccg
    12481 tcgtgcgccg ctggtactgg aggtcaacgg ggtgcgtcat cccctcactc ccccgggcct
    12541 gacgatcggc cgaggttccg atgctgacat tcgcatcaac gatccgggca tttctcgtct
    12601 ccatgctcgt gtcaacgtct ggccccaggg cgacggaatc ggcctgtcca tcgaggatct
    12661 caactccacc aatggggtgt cggtcaacgg agtcaaggtc tccagcgctg agatcagcga
    12721 cgggtcacgc atcgagatcg gctccacacg gatgctggtc cattctccga cggggatgtg
    12781 atcgtgagcg aattcctcgt cacactgtta cgcattgcct acttggcggt gttgtggatc
    12841 ttcatcctgc tcgtcacgaa cgtcattcgt accgacatct acggtcaccg ggtacctcac
    12901 aatgctgaag ccgctgccgt gggtcctggg cgaggtggta agggccgcaa ggctcgtcgt
    12961 cgtgaggtcg ccccggtacc gactggtctg caggtcatct ccggcagtgg ggccggcaca
    13021 tatgtcccgc tggccaacgg cgtcaccgtg gggcgcggca acgactgcac ccttcccatt
    13081 gacgacgact acgcctccac ccgccatgcc gagttcagcc ccggcatcga cggcacgtgg
    13141 ttcgtcgagg atctggcctc gacgaatggc acccatgtca acggtgagcg catcgagaac
    13201 ccgacgcgcc tgtcggtggg ggacgaggtg cgaattggca ggaccgtcat gaccgtcacc
    13261 ggcgggcggt gagcgatggc cttctccctc gacgttcgat gccactccga aattggcctg
    13321 gtgcgacgca acaaccagga ctcggggtac gtctccccga ggatgctcgt cgtcgccgac
    13381 ggcatgggcg gtgccgccgc aggtgacctc gcctccaccg tcgccgtgcg tcacgtcgcc
    13441 cgagctgacg agaggttctc cggggaggac tccccgtgcc gcccgcaggg agaggagatg
    13501 ctcaccgttc tggctggtgc ggtggctgac gccaatgacg aactggccga cctcgtggcg
    13561 tgggactcct ccctggaggg catggggacg accttctgcg gagcgatgtt ctcaggcacc
    13621 cagctcggcg tggtccacat cggtgactcc cgcggctacc tgctgcgtca gggccgcatg
    13681 aagcggatga cccacgacca ctcgtgggtg cagtccctca tcgatgatgg tcggatcacc
    13741 cccgaggagg ccgccgttca tccgcatcgg tctctccttc tcaaggtgct caatggccag
    13801 ccccagcacg tcccggacac ccagatcgtg gatcttcggt tgggagaccg cattctcttc
    13861 tgctctgacg gactgtgcgg tctcgtcgac gacgagacga tcgccgagca cctcagcacc
    13921 accaatctgg acgacgtcgt cgatctgctg gcgacggacg cccatgccgg tggcggcacc
    13981 gacaacatca ccatcgtcgt cgccgaggtc gtcggggctg atcccgtcct ggacgcctcc
    14041 gagccccaca tcatcggggc agcgacgacc cgcaaggttc ccgagcacga ggtcaccgct
    14101 ccgctctccg tcgagcaacc gtcctccgcg acgaaggacg ccggcacgtc gaccgtgctc
    14161 ttcgactccg aggcggagga gtcgatgcgc tatgcgcccg tggattcccg gacccgccgt
    14221 cgtcgccact ggctgtggcc cgtggtcgtc ctcgccgtcg ccgctgtcgt cgtcggcggc
    14281 atcttcggca ctcgcgccta cctcaacacc cagtactacg tgggtaccga cggcaacgcg
    14341 gtggcgattt atcagggatc accggacagc ctggcgtgga tccagctctc ccacgtcgct
    14401 gagacgacgg acgtcaagac cactgatctt ccgcgctact accgaaatcg agtctcggag
    14461 aacatccgcg tctcctcgat ggagtccgcc cactccacgg ttgctgagct gcgtaccgga
    14521 gccgagcatt gcaaggccgt gcgcgaaatg gcgacgaccc cgcctgctgc cccgaccaga
    14581 ccctcgacga ccctatcggc atcacctcaa tcgtccgcca gcagttccgg tattcctcac
    14641 ccgtccgcag taccgacccc cgcgatgccc tcaccgagcg cctcggggca tgaggtggac
    14701 ctccccgccg tcagttcggg tgattgctga tgagtgtcgt accggaattc gatgacggca
    14761 ccgtcgtcgt ccagtccaag agacgctgga cggaactctt catgcttctc atcgcctggg
    14821 ccattggctt cggcggctgg gtactcaccg agctcaacat caaccatgag ttgcccgaga
    14881 cctggatgac ggtcggcggt gtgtggctgg ggatggctgt catcgcgcac atcttcgtga
    14941 ggatcgtcat tccttacgcc gaccccgtga ttcttcccat cgtcttcacc ctcaatgggc
    15001 tcgggctcgc gatgatccac cgcatcgacc ttgtccccga cccgaacaag aaccggatgg
    15061 acacccaggc catgtggacg gccctgggcc tcatcttgtt cctgacgacc ctgctcgtcc
    15121 tgcgggatca tcgcaaactg cagaagtacc cctacgtgct gttcatcgtc ggcctgggat
    15181 tcctcttgct gcccctggtc cccggcctgg ggatgtcagt gctcggatcg cgagtgtgga
    15241 tccgcattgg ctcctacagc ttccagcctg ccgaggtgtc gaaggtggtg ctagccatcg
    15301 ccttcgcggc ttaccttgtg gacaaccgcg acgtcctctc ccgcgccggc cacagaatcc
    15361 tgggcatcac cctgctgcgt gcccgtgatc tcggcccgat cgcagtgatg tgggtcgcga
    15421 cgatgctcgt catcgtctac cagaatgacc tgggcaccgg aatgctcttc tacggcatgt
    15481 tcgtcgtcat gctgtacctc acgaccgagc gtgtcggatg ggcgattctg ggagcggtca
    15541 gcctcgtcgg tggcgcggcg ctggcgtacg ccttcttcgg ccacgtccgc atccgtttcg
    15601 attcctggct gcaccccttc accgattaca gccagaatta ccagatcatc caggctcagt
    15661 tcgggctcgc ctggggtggt ctcgccggac gcggctgggg gctgggacgt cccgggatgg
    15721 tgcccttggc atggagcgac ttcatcgcga cttcgatcgg agaggaactc ggcgtcactg
    15781 gcctcatggc cgtcatcatg atgttcttca tcctcaccgc tcgcggtatg cgcaccgccc
    15841 tcggctgccg tgacgagttc ggcaagctca tggtcgctgg actgtccttc acccttgctc
    15901 tccaggtctt cgccatcatc ggtggcgtca cccggctgct gccgctcact ggcctgacga
    15961 cgccgttcat gagtcaaggc gggtcgtccc tggtcgccaa ctgggtcatc gtcgcgatca
    16021 tcatgatcgt ctcgcaccgc aatcggaaac cggccgacga cttcaccgcc accgtgcccg
    16081 ttgatcctca agcccaagaa gccaccaccg tcatcccgaa tggaggcacg cgatgaacaa
    16141 gcaaattcgc ggagtctccc tgctcgccgg gctgatgttc atggctctca tggtcaatct
    16201 caccggatcg gccatcttcc ggcaggccgg cctcaacaac gatcctcgta acgtccgggt
    16261 gcgcgacgcc gagttctccc agaaccgggg cgacatcctc gtcggttcga tgcccatcgc
    16321 gaccaccaag tccagggatg gcaagttcgc ctaccagcgc gtctatccct ctggcccgga
    16381 gtacgccccg atcaccgggt attactccta ctactacggg cgctccatgc tcgagcagac
    16441 ccagaacgcc cagctgacgg gtacctcgga cgcccagtgg ctttcccgga tcacgggcac
    16501 cctgtctggc cacaagcctg aaggtggctc gatcacgacg acggtcaacg ccaaggccca
    16561 ggatgccgcg tgggaaggcc tcagaggcaa gaagggcgct gtcgtcgcga tggactacac
    16621 cactggcgcg gtgctggcca tggcgtcctc cccctcctac gaccccaacg atctggcctc
    16681 ccaacgcctc aacgacacca gccaggcgtg gaaggaactc gttgcggaca agtcgtctcc
    16741 gttgtccaac cgcgccagcc gtgagatcta ccctcccggt tcgaccttca aactggtgac
    16801 ggccgctgcg gccctgcaga acggttacaa cccgaactcc acagtggatg cgccggagaa
    16861 ctggatcctg cccggcaccc gcactccgtt gacgaacgag acctattgcg ggggcaagca
    16921 gatcactctc acccgtgccc tcgacatctc gtgcaacacc gccttcggca agctcggagt
    16981 gggcctgggc caagacaaga tcaatgccca ggctgaggaa tttggatttg gcaaggtcgt
    17041 cgactccgac atctcgtcgg tcgcctcgaa gttccccaag gacatgaccg atgctcagct
    17101 cgcgcagagt tccatcggcc agttcgacgt cgcagcctcc cctctccaga tggcgatggt
    17161 gactgccggc atcgccaatg gcggcaagct catgacgccg tatctcaccg cgcaggtccg
    17221 ggcatcgaac cttcaggtgg tttccgagca tcgtcccaag cagatgtctc agccgatgac
    17281 gaaggagtcg gccgagcaac tgaagtcgat gatggtctcg gtggtcaaca acggcactgg
    17341 taagagggca cgcattgacg gggtcactgt gggcggcaag accggtactg cgcagacgat
    17401 gagggggaag gctccctacg catggttcgt ggggtggtcc gacaagccac acgtcgcagt
    17461 ggcggccttc atccagtcgt cgaacaccga catcgacgag atctccggag gccggctcgc
    17521 ggctcccatc gccagagatg tcatcgaggc gatgcgatga caaccacaca catgaccagc
    17581 acacttcacc acgtctcacc acaaagggga tccctcaatg agcactgaga gttggctctc
    17641 cgggcgttac gaactgcaga acctcatcgg ccgtggcggc atggccgatg tctggagggc
    17701 ccgcgatcac cgtctcggtc gcgacgtcgc ggtcaagagg ttgcgcgccg acctcgccag
    17761 cgacgacacc ttccaggcga ggttccagcg tgaggcacag tcggctgcgc gcctcaacca
    17821 cccgaacatc gtcgccgtgt atgacactgg tgagacgcaa gatccgacaa ccggcctgca
    17881 ggtgccttac atcgtcatgg aactcattga cggtcacacc ctgcgcgacg tgctgcgcga
    17941 cggccgtaag atccttcccc gccgcgcttt ggagttcacc cagggtgtgc tcgatgcact
    18001 gagttattcc cacgctgccg gcatcgtcca ccgtgacatc aagccggcca atgtcatgct
    18061 gacccgcgag ggttacgtca aggtgatgga cttcggcatc gcccgcgcgg ttgccgacac
    18121 ctccgccacc atgacccaga ccgccgccgt catcggcacc gcccagtacc tctccccgga
    18181 gcaggctcgc ggcgagaccg tcgacaaccg tgctgacatc tacgccaccg gctgtctgct
    18241 gtacgagctg ctcgtcggac gcccgccatt catcggcgac tcccctgtct cggtggccta
    18301 ccagcacgtc cgcgagatcc cggcaccgcc gtcctcgctg gattccgaga tcactggcga
    18361 gatggacgcc atcaccctca aggcgctggc gaaggagcgg gctgatcgct accagaccgc
    18421 caagcagatg cgtgacgaca ttgatcgcct gctgtcaggg cgcgaaccgc tggcgatgca
    18481 ggctcacgcc gatcccgatg ccgacacgga ggagcagacc cacctcatcc ccgctgctgc
    18541 ggcaacggcc gccgcgcctc ctgccgcgcc ggctgccgct gcacagcgag acgaggccac
    18601 ccccgctcaa accgagagcc ctgcagaacc ggaagagcct aagcgcaagc gttggccggt
    18661 cgtcctcgtg acgatcctgg tcgtcgcgtt gctcgcgctg ctcggattcg ggttgcacag
    18721 gatgctcggg ccttcctcgg cccccacctc gtcgccgacg ccgtcgaaaa ccgtgaagat
    18781 ggtcgatgtc ccggcggtca ctggtctgag ccagcaggga gccacgtcga ccctcgagaa
    18841 tgccggcctc aaggtgaagg tcgagcacgt ccagaaggac gagtcgactg ccaaccaggt
    18901 tgtctcgcag aatcctgctg ccaaccagaa ggtccctgag ggcagcaagg tgacgatcac
    18961 cgtcaatgac gggccaaaga agttgacgat cccgcagaac atcgtcggga tgccgaagtc
    19021 ggatgccgtc aaggccctca aggacgccgg attctcggac aaccagatca gggtcaacga
    19081 cgatgacccc aagaccgagg cgaataccgc caaggcgggc accgttgact ccgtccgccc
    19141 gagtgcgggt acctctctga cccccgaaca gcaggtgacg ctgacggtcg cgactggtaa
    19201 gtcggtcgtc cccaacctca agggcatgag cgtcgaagag gcctacgccg ctgccagctc
    19261 gaacggattc tccatctccg tggagcgtca gacgacatcc tcggctgccc ccggcacggt
    19321 gttcagccag gacccggatt acggggccac tgccaagagg tcgaccgcca tcaaggtgct
    19381 cgtcgccgtg aagccgtcgg aaccgaccca cgaggccccg acgagcccta ctccgagcga
    19441 ggacgacccc tcaccggttc cgacgtcgac ggccagtccg tcgtcatctc acggctgaat
    19501 cagcggtccg ccgcgctcat cagcgggctc atctggctgg cgcgggaggg ggcttccggg
    19561 tccccgcact ccatcagcca ggtggcgagc atctggtgac cgtgctggga gagtactgac
    19621 tcggggtgga actgcacccc ctcgaccggc agtctgcggt gacgcaggcc catgacaaca
    19681 ccggtgtccg tgcgtgctgt cacttccagc tcggccggga tctcgtccac ggccaaggag
    19741 tggtagcgag tgacgacgag cgggtctggc aagccagcga aaaccccctt accttcgtgg
    19801 tgaatcggcg aggtcttgcc gtgcagctgt tcctcggcgc gtccgacatg acctccccac
    19861 gcaatggcca tagcctgcat gcccaggcac acaccaaaga tcggtcggcg ggcgccgcgc
    19921 aggatgtcca cgcacactcc ggcgtcctcc ggatgtccgg ggccgggtga cagcaggatg
    19981 ccgtcgaagg gatcccacca ctgcggatcc tcgaagagag gatcatcgtt gcgaaccacc
    20041 gtggtgtctg ccccgatctg tcccaggtag gacacgagat tccacacgaa ggagtcatag
    20101 ttgtcgacga cgaggatcct ggctgtcatg ggatcattgt gtcgcaggcc ggcgtcgaga
    20161 cgccatcatg ctcaggttgt gtcaggcgca ccgactcagc ggggagtggc gtggcccatg
    20221 gcgacggtgc cggtgtaggc cggcaccgtg accgtaccga cccgctccac
//
