LOCUS       c00001_NZ_CABK..       25026 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKQE010000001.1 Ralstonia pickettii isolate MGYG-HGUT-01384,
            whole genome shotgun sequence.
ACCESSION   c00001_NZ_CABK..
VERSION     c00001_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:49:43
            Original ID  :: NZ_CABKQE010000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1554571
            Orig. end    :: 1579597
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25026
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[1564571:1569597]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15026
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..25026
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..25026
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="3"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             643..1332
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 168.9; E-value: 2e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1476"
                     /transl_table=11
                     /translation="MTAVTSSVSNHPRFDAILFDCDGVLVDSEPIVNRLIWEMLIELGI
                     DISLEDSIQRFLGKAIREELDAIAEMRGAPLPPNWLSTFQARRNVLLEAEVEAVPHIGH
                     AIDVLSRLGLPMAVASGADRMKVELQLNRTGLIEHFQPTDVRIFSATEVARSKPAPDVY
                     LLAASSLGVSPSRCLVIEDSPTGVTAGHAAGMTVLAYAGRNAPGPLIAAGATRTFTDMR
                     ELPELLA"
     PFAM_domain     691..1239
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1476_0053"
                     /evalue="1.10E-25"
                     /label="ctg1_1476"
                     /locus_tag="ctg1_1476"
                     /protein_end="199"
                     /protein_start="16"
                     /score="90.8"
                     /tool="antismash"
                     /translation="ILFDCDGVLVDSEPIVNRLIWEMLIELGIDISLEDSIQRFLGKAI
                     REELDAIAEMRGAPLPPNWLSTFQARRNVLLEAEVEAVPHIGHAIDVLSRLGLPMAVAS
                     GADRMKVELQLNRTGLIEHFQPTDVRIFSATEVARSKPAPDVYLLAASSLGVSPSRCLV
                     IEDSPTGVTAGHAAGMTVLA"
     aSDomain        946..1236
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1476_0015"
                     /evalue="1.40E-14"
                     /identifier="TIGR01509"
                     /label="ctg1_1476"
                     /locus_tag="ctg1_1476"
                     /protein_end="198"
                     /protein_start="101"
                     /score="52.5"
                     /tool="antismash"
                     /translation="IGHAIDVLSRLGLPMAVASGADRMKVELQLNRTGLIEHFQPTDVR
                     IFSATEVARSKPAPDVYLLAASSLGVSPSRCLVIEDSPTGVTAGHAAGMTVL"
     CDS             1332..1772
                     /locus_tag="ctg1_1477"
                     /transl_table=11
                     /translation="MPAAQTQPIGPADACPCGNGAYARCCGPFHAGEAVAATAEQLMRS
                     RYSAYVLGDTAYLRRTWHPSTCPVDLETSEADAAATRWLGLDVRRHTPQDATHATVEFV
                     ARYKVGGRAHRLHETSRFVRLDASGAESAEGRWLYVDGTFPD"
     PFAM_domain     1443..1757
                     /aSDomain="UPF0225"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17775.3"
                     /description="UPF0225 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1477_0054"
                     /evalue="2.30E-27"
                     /label="ctg1_1477"
                     /locus_tag="ctg1_1477"
                     /protein_end="142"
                     /protein_start="37"
                     /score="95.8"
                     /tool="antismash"
                     /translation="TAEQLMRSRYSAYVLGDTAYLRRTWHPSTCPVDLETSEADAAATR
                     WLGLDVRRHTPQDATHATVEFVARYKVGGRAHRLHETSRFVRLDASGAESAEGRWLYVD
                     G"
     CDS             1801..3408
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 531.3; E-value: 4.8e-161)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1478"
                     /transl_table=11
                     /translation="MPTLETKLNPRAEDFKANADAMRALVADLRDKVARIAQGGGDDAR
                     AKHLARGKLLPRDRVQQLLDPGTPFLEFSQLAAYGMYDNAAPGAGIITGIGRISGQECV
                     IVCNDATVKGGTYYPMTVKKHLRAQEIAEQNHLPCVYLVDSGGANLPNQDDVFPDRDHF
                     GRIFYNQANLSSKGIPQIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLAGPPLVKAA
                     TGEVVSAEDLGGADVHTRLSGVADYFANNDSHALAQARSIVAHLNRRKPEQVQIHAPVE
                     PRFPAEELYGVIPTDTRKPFDVREVIARIVDDSAFDEFKARYGTTLVCGFARIWGYPVG
                     IIANNGILFSEAALKGAHFIELCCQRKIPLVFLQNITGFMVGRKYENEGIAKNGAKMVT
                     AVATAQVPKFTVIIGGSFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVR
                     RDGIEAKGGQWSADEEAAFKAPIRDQYERQGHPYYASARLWDDGVIDPADTRSVLGLGL
                     SASLNAPIGDMNFGVFRM"
     PFAM_domain     1942..3372
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1478_0055"
                     /evalue="1.30E-153"
                     /label="ctg1_1478"
                     /locus_tag="ctg1_1478"
                     /protein_end="524"
                     /protein_start="47"
                     /score="512.3"
                     /tool="antismash"
                     /translation="HLARGKLLPRDRVQQLLDPGTPFLEFSQLAAYGMYDNAAPGAGII
                     TGIGRISGQECVIVCNDATVKGGTYYPMTVKKHLRAQEIAEQNHLPCVYLVDSGGANLP
                     NQDDVFPDRDHFGRIFYNQANLSSKGIPQIAVVMGSCTAGGAYVPAMSDESIIVKEQGT
                     IFLAGPPLVKAATGEVVSAEDLGGADVHTRLSGVADYFANNDSHALAQARSIVAHLNRR
                     KPEQVQIHAPVEPRFPAEELYGVIPTDTRKPFDVREVIARIVDDSAFDEFKARYGTTLV
                     CGFARIWGYPVGIIANNGILFSEAALKGAHFIELCCQRKIPLVFLQNITGFMVGRKYEN
                     EGIAKNGAKMVTAVATAQVPKFTVIIGGSFGAGNYGMCGRAYSPRFLWMWPNARISVMG
                     GEQAASVLATVRRDGIEAKGGQWSADEEAAFKAPIRDQYERQGHPYYASARLWDDGVID
                     PADTRSVLGLGLSASLNAP"
     CDS             3440..4378
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1479"
                     /sec_met_domain="Peptidase_S9 (E-value: 3.8e-12, bitscore:
                     43.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNSNTARTWRSALAAVGCALLLAAAHASETAQSGISEIIVEVPKS
                     AGIFTLKLETTVYKPAGDGPFPLIVLNHGKARGKAAFQARARYSEQAAALVARGYVVAI
                     PMRQGFAKSGGAYIGSGCNVEANGIIQAEDVVATLDYMTAQPYVDRNRIVVMGQSHGGL
                     TTLAFGTIAYPGVRGLVNFAGGLRNDTCVDWEGNLVRAFETYGRQSRYPSLWFYGDNDS
                     YWPKPMPDRMFAAYTSAGGKGRLVDFGTFKSDSHGMFASHAGLGIWLPQVDAFLRELGL
                     PAGPVQAVAPGSNAEASGADDPKSDTNKDPE"
     PFAM_domain     3701..3949
                     /aSDomain="Peptidase_S9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00326.23"
                     /description="Prolyl oligopeptidase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1479_0056"
                     /evalue="3.50E-11"
                     /label="ctg1_1479"
                     /locus_tag="ctg1_1479"
                     /protein_end="170"
                     /protein_start="87"
                     /score="43.1"
                     /tool="antismash"
                     /translation="YSEQAAALVARGYVVAIPMRQGFAKSGGAYIGSGCNVEANGIIQA
                     EDVVATLDYMTAQPYVDRNRIVVMGQSHGGLTTLAFGT"
     CDS             4375..5169
                     /NRPS_PKS="Domain: ECH (11-254). E-value: 8.9e-54. Score:
                     174.2. Matches aSDomain: nrpspksdomains_ctg1_1480_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 231.6; E-value:
                     1.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1480"
                     /transl_table=11
                     /translation="MNTFETLAFAQNGAVATLTLNRPDVRNAFNETVIAELTGAFRALA
                     DEPGVRAIVLTGNGPAFCAGADLNWMKKMAGYSDDENRADALRLAEMLRAIYTCPKPVI
                     ARVQGDTYAGGVGLVAACDIVVAVDTANFCLSEAKLGLIPATISPYVIRALGEQASRRY
                     FITAERFSAAEAHRLGLVHELVSADALDAKVADITAALVANSPNAVRESKRLVREVSGA
                     AVNDALLADTAERIAAIRASEEGREGVQSFLGKRKPNWLLPA"
     aSDomain        4408..5136
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1480_ECH.1"
                     /evalue="8.90E-54"
                     /label="ctg1_1480_ECH.1"
                     /locus_tag="ctg1_1480"
                     /protein_end="254"
                     /protein_start="11"
                     /score="174.2"
                     /tool="antismash"
                     /translation="NGAVATLTLNRPDVRNAFNETVIAELTGAFRALADEPGVRAIVLT
                     GNGPAFCAGADLNWMKKMAGYSDDENRADALRLAEMLRAIYTCPKPVIARVQGDTYAGG
                     VGLVAACDIVVAVDTANFCLSEAKLGLIPATISPYVIRALGEQASRRYFITAERFSAAE
                     AHRLGLVHELVSADALDAKVADITAALVANSPNAVRESKRLVREVSGAAVNDALLADTA
                     ERIAAIRASEEGREGVQSFLG"
     PFAM_domain     4408..5154
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1480_0057"
                     /evalue="1.40E-58"
                     /label="ctg1_1480"
                     /locus_tag="ctg1_1480"
                     /protein_end="260"
                     /protein_start="11"
                     /score="198.3"
                     /tool="antismash"
                     /translation="NGAVATLTLNRPDVRNAFNETVIAELTGAFRALADEPGVRAIVLT
                     GNGPAFCAGADLNWMKKMAGYSDDENRADALRLAEMLRAIYTCPKPVIARVQGDTYAGG
                     VGLVAACDIVVAVDTANFCLSEAKLGLIPATISPYVIRALGEQASRRYFITAERFSAAE
                     AHRLGLVHELVSADALDAKVADITAALVANSPNAVRESKRLVREVSGAAVNDALLADTA
                     ERIAAIRASEEGREGVQSFLGKRKPNW"
     CDS             5213..6292
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF06968"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1481"
                     /sec_met_domain="PF06968 (E-value: 1.6e-21, bitscore: 73.2,
                     seeds: 824, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.1e-18, bitscore: 62.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSTPLNFVPNAAKAPVTPGQAPDARWSREAIEALFALPFNDLLF
                     QAQQVHRANFDANAVQLSTLLSIKTGGCPEDCSYCPQSARYDTGVEAEKLMPIDAVLEA
                     ASRAKQNGASRFCMGAAWRNPKPHQLDAVADMVRGVKAMGLETCVTLGMLKQEQAAQLK
                     EAGLDYYNHNLDTAPEFYGEIITTRTYQDRLDTLEHVRDAGINVCCGGIVGLGESVHER
                     AGLIAELANMEPYPDSVPINNLVKVEGTPLAGNEELDPFDFVRTIAVARITMPKAMVRL
                     SAGREAMDDALQALCFMAGANSIFYGEKLLTTDNPEADADRKLLARLGMRVEVQDHMHH
                     ESHVGAQSSHCHIDITPAD"
     aSDomain        5315..6202
                     /aSDomain="TIGR00433"
                     /aSTool="tigrfam"
                     /description="bioB: biotin synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1481_0016"
                     /evalue="6.00E-125"
                     /identifier="TIGR00433"
                     /label="ctg1_1481"
                     /locus_tag="ctg1_1481"
                     /protein_end="330"
                     /protein_start="34"
                     /score="414.4"
                     /tool="antismash"
                     /translation="LFALPFNDLLFQAQQVHRANFDANAVQLSTLLSIKTGGCPEDCSY
                     CPQSARYDTGVEAEKLMPIDAVLEAASRAKQNGASRFCMGAAWRNPKPHQLDAVADMVR
                     GVKAMGLETCVTLGMLKQEQAAQLKEAGLDYYNHNLDTAPEFYGEIITTRTYQDRLDTL
                     EHVRDAGINVCCGGIVGLGESVHERAGLIAELANMEPYPDSVPINNLVKVEGTPLAGNE
                     ELDPFDFVRTIAVARITMPKAMVRLSAGREAMDDALQALCFMAGANSIFYGEKLLTTDN
                     PEADADRKLLARLGM"
     PFAM_domain     5420..5875
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1481_0058"
                     /evalue="9.00E-17"
                     /label="ctg1_1481"
                     /locus_tag="ctg1_1481"
                     /protein_end="221"
                     /protein_start="69"
                     /score="62.0"
                     /tool="antismash"
                     /translation="TGGCPEDCSYCPQSARYDTGVEAEKLMPIDAVLEAASRAKQNGAS
                     RFCMGAAWRNPKPHQLDAVADMVRGVKAMGLETCVTLGMLKQEQAAQLKEAGLDYYNHN
                     LDTAPEFYGEIITTRTYQDRLDTLEHVRDAGINVCCGGIVGLGESVHE"
     PFAM_domain     5930..6202
                     /aSDomain="BATS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06968.15"
                     /description="Biotin and Thiamin Synthesis associated
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1481_0059"
                     /evalue="2.90E-20"
                     /label="ctg1_1481"
                     /locus_tag="ctg1_1481"
                     /protein_end="330"
                     /protein_start="239"
                     /score="72.3"
                     /tool="antismash"
                     /translation="PINNLVKVEGTPLAGNEELDPFDFVRTIAVARITMPKAMVRLSAG
                     REAMDDALQALCFMAGANSIFYGEKLLTTDNPEADADRKLLARLGM"
     PFAM_domain     6947..7276
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1482_0060"
                     /evalue="7.30E-44"
                     /label="ctg1_1482"
                     /locus_tag="ctg1_1482"
                     /protein_end="110"
                     /protein_start="0"
                     /score="148.9"
                     /tool="antismash"
                     /translation="MITKLLIANRGEIACRVAATCRKLGIRTVAVYSDADANARHVAAC
                     DEAIHIGEPAARDSYLRADRILEAARATGAQAVHPGYGFLSENEAFAKACADAGIIFVG
                     PPASAI"
     CDS             6947..8971
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     730.9; E-value: 2.5e-221)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1482"
                     /sec_met_domain="ATP-grasp (E-value: 2e-08, bitscore: 30.9,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITKLLIANRGEIACRVAATCRKLGIRTVAVYSDADANARHVAAC
                     DEAIHIGEPAARDSYLRADRILEAARATGAQAVHPGYGFLSENEAFAKACADAGIIFVG
                     PPASAIEAMGSKSAAKALMETAGVPLVPGYHGDNQDAAFLRTQADRIGYPVLIKASAGG
                     GGKGMRVVESGDAFEASLASVKREASSSFGDDRVLIEKYLTRPRHIEIQVFADSFGDAV
                     YLFERDCSVQRRHQKVLEEAPAPGMTLDRRRAMGEAAVAAARAVGYVGAGTVEFIVDED
                     GTFYFMEMNTRLQVEHPVTEMITGEDLVEWQLRVASGEPLPRTQDELHIHGHALEARIY
                     AENPDRDFLPSIGTLKVLRTPAAVEFTVGAQANGEPAAVRIDAGVREGDAISPYYDPMI
                     AKLIVWGRDREEALARMLQALGSFHLVGLSSNVAFLRRLVASKPFATADLDTGLIARNH
                     DTLFPAAPDVPLDAIALAVAALLAREARSLRTDTRDPHSPWARGSGWRLNGAAERTLRF
                     THGDQSIDATLIYGRYGSRLKVGGSEAPFTSQRHAETFTVTLGTHKATGQVHADGDTFH
                     VFTGGAHWTLERHDPLAHAGEADDEGGKLTAPMPGKVIAVLAAPGQTVTKGAPLVVMEA
                     MKMEHTLTAPANGVVESVLYGVGDQVTEGVQLLAFKPAE"
     PFAM_domain     7292..7915
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1482_0061"
                     /evalue="9.00E-76"
                     /label="ctg1_1482"
                     /locus_tag="ctg1_1482"
                     /protein_end="323"
                     /protein_start="115"
                     /score="254.2"
                     /tool="antismash"
                     /translation="KSAAKALMETAGVPLVPGYHGDNQDAAFLRTQADRIGYPVLIKAS
                     AGGGGKGMRVVESGDAFEASLASVKREASSSFGDDRVLIEKYLTRPRHIEIQVFADSFG
                     DAVYLFERDCSVQRRHQKVLEEAPAPGMTLDRRRAMGEAAVAAARAVGYVGAGTVEFIV
                     DEDGTFYFMEMNTRLQVEHPVTEMITGEDLVEWQLRVASGEPLPR"
     PFAM_domain     7952..8311
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1482_0062"
                     /evalue="2.10E-33"
                     /label="ctg1_1482"
                     /locus_tag="ctg1_1482"
                     /protein_end="455"
                     /protein_start="335"
                     /score="114.7"
                     /tool="antismash"
                     /translation="EARIYAENPDRDFLPSIGTLKVLRTPAAVEFTVGAQANGEPAAVR
                     IDAGVREGDAISPYYDPMIAKLIVWGRDREEALARMLQALGSFHLVGLSSNVAFLRRLV
                     ASKPFATADLDTGLIA"
     PFAM_domain     8756..8947
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1482_0063"
                     /evalue="1.80E-16"
                     /label="ctg1_1482"
                     /locus_tag="ctg1_1482"
                     /protein_end="667"
                     /protein_start="603"
                     /score="59.8"
                     /tool="antismash"
                     /translation="KLTAPMPGKVIAVLAAPGQTVTKGAPLVVMEAMKMEHTLTAPANG
                     VVESVLYGVGDQVTEGVQL"
     CDS             9058..9999
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 155.6; E-value: 2e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1483"
                     /transl_table=11
                     /translation="MHIQIYTPDGKPQPWLDGFAQALPEARLSVWEQGAVQDADYAVVW
                     QPPADMLRDRRDLRAVFNLGAGVDAILGLRAQAPDAIPEGLPIVRLDDAGMAAQMGEYV
                     THAVLRFFRRLDEYERQQQAKMWRFLKPFNRDEFVVGVLGLGVLGTHIARTLAGFGFPV
                     RGWSRSAKHVEGVDCRSGSDALPGFLAGTRVLVNVLPLTADTENVIDAKLLAQLAPGAF
                     VVNVARGKHVVEDDLLAAVRSGHIAGAALDVFRTEPLPADHPFWTEPRIHITPHISALT
                     LREVSIAQIARKIRALEAGEPIAGIVDLQRGY"
     PFAM_domain     9376..9891
                     /aSDomain="2-Hacid_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02826.21"
                     /description="D-isomer specific 2-hydroxyacid
                     dehydrogenase, NAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1483_0064"
                     /evalue="4.70E-46"
                     /label="ctg1_1483"
                     /locus_tag="ctg1_1483"
                     /protein_end="278"
                     /protein_start="106"
                     /score="156.4"
                     /tool="antismash"
                     /translation="AVLRFFRRLDEYERQQQAKMWRFLKPFNRDEFVVGVLGLGVLGTH
                     IARTLAGFGFPVRGWSRSAKHVEGVDCRSGSDALPGFLAGTRVLVNVLPLTADTENVID
                     AKLLAQLAPGAFVVNVARGKHVVEDDLLAAVRSGHIAGAALDVFRTEPLPADHPFWTEP
                     RIHITPHIS"
     CDS             10001..10930
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 210.7;
                     E-value: 6.8e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1484"
                     /sec_met_domain="HMGL-like (E-value: 6.7e-53, bitscore:
                     176.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIPNFVKVVEVGPRDGLQNEKSPVSTDTKVELVNRLSEAGFVNV
                     EAASFVSPKWVPAMADGADVMARIQRRPGTLYSVLTPNMKGFEGAAAAGADEIVIFSAA
                     SEAFAQKNINCTIAESIERFVPVAKAAKDAGIRVRGSISCSLGCPYQGEVPVSSVVDVI
                     KRMADLGCDEIDIADTIGVGTAGRVKTVMEAAAATFPIDRLSGHFHDTYGQALANILAS
                     LEVGIAIFHASVAGLGGCPYAKGATGNVATEDVLYLLHGLGIRTGIDLDKVVLAGDFIS
                     QAIGRPTASRAGRALLLKLQDQIAQACI"
     PFAM_domain     10019..10834
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1484_0065"
                     /evalue="1.50E-52"
                     /label="ctg1_1484"
                     /locus_tag="ctg1_1484"
                     /protein_end="278"
                     /protein_start="6"
                     /score="178.8"
                     /tool="antismash"
                     /translation="VKVVEVGPRDGLQNEKSPVSTDTKVELVNRLSEAGFVNVEAASFV
                     SPKWVPAMADGADVMARIQRRPGTLYSVLTPNMKGFEGAAAAGADEIVIFSAASEAFAQ
                     KNINCTIAESIERFVPVAKAAKDAGIRVRGSISCSLGCPYQGEVPVSSVVDVIKRMADL
                     GCDEIDIADTIGVGTAGRVKTVMEAAAATFPIDRLSGHFHDTYGQALANILASLEVGIA
                     IFHASVAGLGGCPYAKGATGNVATEDVLYLLHGLGIRTGIDLDKVVLAGD"
     CDS             10953..11453
                     /locus_tag="ctg1_1485"
                     /transl_table=11
                     /translation="MTATDTKAPLPESAQRVADHLRTLGYEKNIVMLPATGKTSAEAAA
                     GLGCSVAEIAKSIIFRRAEDDVPVLVIASGTNRVDEAKVSAHVGALAKADAKFVREKTG
                     YAIGGVCPVGHAVKPVMLLDQDLFQYDSLWAAAGHPHAVFNLTPAELEAMTGAPVADIA
                     QRD"
     PFAM_domain     11061..11408
                     /aSDomain="tRNA_edit"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04073.17"
                     /description="Aminoacyl-tRNA editing domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1485_0066"
                     /evalue="1.20E-22"
                     /label="ctg1_1485"
                     /locus_tag="ctg1_1485"
                     /protein_end="152"
                     /protein_start="36"
                     /score="80.3"
                     /tool="antismash"
                     /translation="GKTSAEAAAGLGCSVAEIAKSIIFRRAEDDVPVLVIASGTNRVDE
                     AKVSAHVGALAKADAKFVREKTGYAIGGVCPVGHAVKPVMLLDQDLFQYDSLWAAAGHP
                     HAVFNLTPAELE"
     CDS             11462..11728
                     /locus_tag="ctg1_1486"
                     /transl_table=11
                     /translation="MDACTRAQLKRSLGKLRNSQPQAERAQPVASPCISVCKMDEARGL
                     CIGCMRTIDEIASWSTMNDAARLAVWKTLPERACAWLNDAPCA"
     PFAM_domain     11552..11692
                     /aSDomain="DUF1289"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06945.15"
                     /description="Protein of unknown function (DUF1289)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1486_0067"
                     /evalue="4.40E-22"
                     /label="ctg1_1486"
                     /locus_tag="ctg1_1486"
                     /protein_end="77"
                     /protein_start="30"
                     /score="77.8"
                     /tool="antismash"
                     /translation="SPCISVCKMDEARGLCIGCMRTIDEIASWSTMNDAARLAVWKTLP
                     ER"
     CDS             11741..12694
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score:
                     73.8; E-value: 2.3e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1487"
                     /transl_table=11
                     /translation="MAEHDVVTLPNSMRVFERGWLSSNNILFFDDEAHGGCALVDSGYL
                     THAPQTVALVQHALRGRPLRRLLNTHLHSDHCGGNAALQALYGSHTRVPAAQIDDVRRW
                     DTDALSYGPTGQECARFALPDSDADAGLSDGMTARLGGFDWQVISAPGHDPHAVILFSP
                     DTRVLISADALWERGFGVIFPELEGESGFAEQQAILERIVQLDALVVIPGHGRPFTNVN
                     AAIDASLGRLAYLRADPERNALHAIRVLVKFKLLEQQALSHEALFAWFTQTTLMPRLHA
                     RFFAAQSMETLLDAAIAALVKAGAATVEHGRILNRD"
     PFAM_domain     11813..12382
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1487_0068"
                     /evalue="2.00E-20"
                     /label="ctg1_1487"
                     /locus_tag="ctg1_1487"
                     /protein_end="214"
                     /protein_start="24"
                     /score="73.8"
                     /tool="antismash"
                     /translation="NILFFDDEAHGGCALVDSGYLTHAPQTVALVQHALRGRPLRRLLN
                     THLHSDHCGGNAALQALYGSHTRVPAAQIDDVRRWDTDALSYGPTGQECARFALPDSDA
                     DAGLSDGMTARLGGFDWQVISAPGHDPHAVILFSPDTRVLISADALWERGFGVIFPELE
                     GESGFAEQQAILERIVQLDALVVIPGH"
     CDS             12756..13433
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 107.1; E-value: 2.5e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1488"
                     /transl_table=11
                     /translation="MPKPATSNPPESATEAAPEAEAPRRKRGRPAQDANEGLRRALIEQ
                     SARLFREKGYGNTTVRDIAAATGVHAGSWFYYFKTKQDILQAVIEHGLTVALADIEAID
                     IEDLPPREAMRQLVRAHLHTILAPHQDFIPVMLYEWRSLDAQAQERIIALKDRYEDIWT
                     RVIDRLRASGEWAHPTPVDRLLMFGALNWTAQWYQAGAGISIDALADQAVLFILRTPPQ
                     PAA"
     PFAM_domain     12879..13019
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1488_0069"
                     /evalue="4.40E-14"
                     /label="ctg1_1488"
                     /locus_tag="ctg1_1488"
                     /protein_end="88"
                     /protein_start="41"
                     /score="52.1"
                     /tool="antismash"
                     /translation="LIEQSARLFREKGYGNTTVRDIAAATGVHAGSWFYYFKTKQDILQ
                     AV"
     PFAM_domain     13077..13409
                     /aSDomain="TetR_C_24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17932.3"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1488_0070"
                     /evalue="8.00E-22"
                     /label="ctg1_1488"
                     /locus_tag="ctg1_1488"
                     /protein_end="218"
                     /protein_start="107"
                     /score="77.7"
                     /tool="antismash"
                     /translation="LPPREAMRQLVRAHLHTILAPHQDFIPVMLYEWRSLDAQAQERII
                     ALKDRYEDIWTRVIDRLRASGEWAHPTPVDRLLMFGALNWTAQWYQAGAGISIDALADQ
                     AVLFILR"
     CDS             complement(13440..15026)
                     /NRPS_PKS="Domain: AMP-binding (24-425). E-value: 2e-99.
                     Score: 324.8. Matches aSDomain:
                     nrpspksdomains_ctg1_1489_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     392.7; E-value: 3.4e-119)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1489"
                     /sec_met_domain="AMP-binding (E-value: 3.4e-108, bitscore:
                     358.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEATPDTALEANLLNRVTLGDTLHRSARKFGAKVALVDGARRMT
                     HGELNADSNRYAHALLASSLKPGDKVAMVCGNSAQFLVAAYGILKAGLVWVPINAMLGP
                     EDVRYILEHAEARHVVIDAALYPALRDTLATLGLPAHQCFGEPVADGPQPVEQALQGHA
                     DTLPAVVIDDRDLALIMYTSGTTGRPKGAMHSHRSVHAALMSNVAGLNLNETDVFSCLL
                     PMFHCAQFATAASAMMVGATLVIQRGFDPAALLDVIANERITQLFGLPLMYAALLHHPL
                     RAQRDLSSLRLCLYAMAPMARPLLERLIAEVCPNFALGSGQTEIFPMTMYFAPDQQLQR
                     TGNYWGQPCMVNEAAVMDDQGNLLGPNQLGEIVHRGPNVMLGYYKDPQATANARRFGWH
                     HTGDLGMWDADGQLQFKDRIKDMIKTGGENVPSVKVEEVLLRHPAVANAAVVGLPHAHW
                     VEAVAAFVCLKPDAHADAAALQAHCRAHLGSFEVPKHIAVVDKLPMTATGKIQKHVLRS
                     ANQTLFEGEAR"
     PFAM_domain     complement(13500..13727)
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1489_0072"
                     /evalue="6.00E-22"
                     /label="ctg1_1489"
                     /locus_tag="ctg1_1489"
                     /protein_end="509"
                     /protein_start="433"
                     /score="78.5"
                     /tool="antismash"
                     /translation="KVEEVLLRHPAVANAAVVGLPHAHWVEAVAAFVCLKPDAHADAAA
                     LQAHCRAHLGSFEVPKHIAVVDKLPMTATGK"
     CDS_motif       complement(13533..13565)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1489_0004"
                     /evalue="8.30E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1489"
                     /protein_end="498"
                     /protein_start="487"
                     /score="-2.7"
                     /tool="antismash"
                     /translation="GSFEVPKHIAV"
     aSDomain        complement(13752..14954)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1489_AMP-binding.1"
                     /evalue="2.00E-99"
                     /label="ctg1_1489_AMP-binding.1"
                     /locus_tag="ctg1_1489"
                     /protein_end="425"
                     /protein_start="24"
                     /score="324.8"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="HRSARKFGAKVALVDGARRMTHGELNADSNRYAHALLASSLKPGD
                     KVAMVCGNSAQFLVAAYGILKAGLVWVPINAMLGPEDVRYILEHAEARHVVIDAALYPA
                     LRDTLATLGLPAHQCFGEPVADGPQPVEQALQGHADTLPAVVIDDRDLALIMYTSGTTG
                     RPKGAMHSHRSVHAALMSNVAGLNLNETDVFSCLLPMFHCAQFATAASAMMVGATLVIQ
                     RGFDPAALLDVIANERITQLFGLPLMYAALLHHPLRAQRDLSSLRLCLYAMAPMARPLL
                     ERLIAEVCPNFALGSGQTEIFPMTMYFAPDQQLQRTGNYWGQPCMVNEAAVMDDQGNLL
                     GPNQLGEIVHRGPNVMLGYYKDPQATANARRFGWHHTGDLGMWDADGQLQFKDRIKDMI
                     KT"
     PFAM_domain     complement(13752..14954)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1489_0071"
                     /evalue="1.80E-100"
                     /label="ctg1_1489"
                     /locus_tag="ctg1_1489"
                     /protein_end="425"
                     /protein_start="24"
                     /score="336.7"
                     /tool="antismash"
                     /translation="HRSARKFGAKVALVDGARRMTHGELNADSNRYAHALLASSLKPGD
                     KVAMVCGNSAQFLVAAYGILKAGLVWVPINAMLGPEDVRYILEHAEARHVVIDAALYPA
                     LRDTLATLGLPAHQCFGEPVADGPQPVEQALQGHADTLPAVVIDDRDLALIMYTSGTTG
                     RPKGAMHSHRSVHAALMSNVAGLNLNETDVFSCLLPMFHCAQFATAASAMMVGATLVIQ
                     RGFDPAALLDVIANERITQLFGLPLMYAALLHHPLRAQRDLSSLRLCLYAMAPMARPLL
                     ERLIAEVCPNFALGSGQTEIFPMTMYFAPDQQLQRTGNYWGQPCMVNEAAVMDDQGNLL
                     GPNQLGEIVHRGPNVMLGYYKDPQATANARRFGWHHTGDLGMWDADGQLQFKDRIKDMI
                     KT"
     CDS_motif       complement(13854..13919)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1489_0003"
                     /evalue="3.20E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_1489"
                     /protein_end="391"
                     /protein_start="369"
                     /score="16.3"
                     /tool="antismash"
                     /translation="GEIVHRGPNVMLGYYKDPQATA"
     CDS_motif       complement(14439..14498)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1489_0002"
                     /evalue="2.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_1489"
                     /protein_end="196"
                     /protein_start="176"
                     /score="26.1"
                     /tool="antismash"
                     /translation="ALIMYTSGTTGRPKGAMHSH"
     CDS_motif       complement(14733..14768)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1489_0001"
                     /evalue="2.70E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg1_1489"
                     /protein_end="98"
                     /protein_start="86"
                     /score="11.3"
                     /tool="antismash"
                     /translation="GILKAGLVWVPI"
     CDS             complement(15111..17105)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     702.7; E-value: 8.9e-213)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1490"
                     /sec_met_domain="ATP-grasp (E-value: 3.9e-08, bitscore:
                     30.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPHAAFRSILIANRGEIALRIMRTARRLGMPTVAVYSDADRDA
                     PHCRAADLALPIGASQPQASYLNVAALLEAARKSGAQAVHPGYGFLAESDAFAGACADA
                     GLVFIGPPAGAIRAMGNKAGAKRLMEAAGVPCVPGYQGEDQSATRMADEAARIGYPVMI
                     KAAAGGGGRGMRRVDRPEAFAAALQSARSEAENAFGSGELILEKAIVEPRHIEIQVFAD
                     AHGNVVHLGERDCSVQRRHQKVIEESPSPAVSPELRARMGAVSVAAARAIGYVGAGTLE
                     FLLAPDGAFYFMEMNTRLQVEHAVTEAIVGVDLVEWQLRVALGEPLPLAQDAIDARRAQ
                     GGHAIEVRLCAEDPQQNFLPQSGTVARWRAPGDVRTDHALADGLVVSPYYDSMLAKIVA
                     HGTDRADACRRLAHALDDCLLLGLPTNRAFLRDCVAHPAFLSGDVSTAFIDRHFPAAMR
                     QAAVPDAAVCQAAAVLLTYLRQDTARRYPAELHGWASSRTYPTLCRFTLDGEAIDMRVR
                     ALGAQQWELAWDGGATQVAVVSAGDGRVTLALGDAFHAVDYAVTASACHFVLNGIEHTA
                     IDTTYAKAERSGAQTGSGRISAPMNGRVVAVHVAEGEAVCAGQVLLVVEAMKMEHSIAA
                     PLAGEVRGLFTQVGAQVAPGGLLMEIAAA"
     PFAM_domain     complement(15123..15320)
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1490_0076"
                     /evalue="5.50E-15"
                     /label="ctg1_1490"
                     /locus_tag="ctg1_1490"
                     /protein_end="661"
                     /protein_start="595"
                     /score="55.0"
                     /tool="antismash"
                     /translation="ISAPMNGRVVAVHVAEGEAVCAGQVLLVVEAMKMEHSIAAPLAGE
                     VRGLFTQVGAQVAPGGLLMEI"
     PFAM_domain     complement(15756..16070)
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1490_0075"
                     /evalue="8.90E-34"
                     /label="ctg1_1490"
                     /locus_tag="ctg1_1490"
                     /protein_end="450"
                     /protein_start="345"
                     /score="115.9"
                     /tool="antismash"
                     /translation="EVRLCAEDPQQNFLPQSGTVARWRAPGDVRTDHALADGLVVSPYY
                     DSMLAKIVAHGTDRADACRRLAHALDDCLLLGLPTNRAFLRDCVAHPAFLSGDVSTAFI
                     D"
     PFAM_domain     complement(16122..16742)
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1490_0074"
                     /evalue="2.00E-73"
                     /label="ctg1_1490"
                     /locus_tag="ctg1_1490"
                     /protein_end="328"
                     /protein_start="121"
                     /score="246.5"
                     /tool="antismash"
                     /translation="KAGAKRLMEAAGVPCVPGYQGEDQSATRMADEAARIGYPVMIKAA
                     AGGGGRGMRRVDRPEAFAAALQSARSEAENAFGSGELILEKAIVEPRHIEIQVFADAHG
                     NVVHLGERDCSVQRRHQKVIEESPSPAVSPELRARMGAVSVAAARAIGYVGAGTLEFLL
                     APDGAFYFMEMNTRLQVEHAVTEAIVGVDLVEWQLRVALGEPLP"
     PFAM_domain     complement(16761..17084)
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1490_0073"
                     /evalue="6.70E-41"
                     /label="ctg1_1490"
                     /locus_tag="ctg1_1490"
                     /protein_end="115"
                     /protein_start="7"
                     /score="139.4"
                     /tool="antismash"
                     /translation="FRSILIANRGEIALRIMRTARRLGMPTVAVYSDADRDAPHCRAAD
                     LALPIGASQPQASYLNVAALLEAARKSGAQAVHPGYGFLAESDAFAGACADAGLVFIGP
                     PAGA"
     CDS             complement(17109..18266)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 360; E-value:
                     2.6e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1491"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 6.3e-29, bitscore:
                     97.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.8e-27, bitscore:
                     92.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.4e-42, bitscore:
                     141.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMG
                     ELGFLGIAKPTEFGGLGLDYSYAMAMAETLGHIHCGGVPMAIGVQTDMATPALARFGSD
                     ELRAQFLAPAISGDAVACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNSLQA
                     DWMCLLANTSDDPAHRNKSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQR
                     YRIGEEGKGFTYQMLQFQEERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWV
                     HFKLAELKTEVEALRALTYRACDLYIQGQDVTELASMAKLKAGRLARIVPDACLQFWGG
                     MGFTWDNPVSRYYRDGRLGSIGGGADEVMLGIICKYMNTLPGKKG"
     PFAM_domain     complement(17142..17582)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1491_0079"
                     /evalue="2.20E-41"
                     /label="ctg1_1491"
                     /locus_tag="ctg1_1491"
                     /protein_end="375"
                     /protein_start="228"
                     /score="141.6"
                     /tool="antismash"
                     /translation="GKGFTYQMLQFQEERLWAAASSLATMTMCIETTAEYARERKLFGA
                     SLLDNQWVHFKLAELKTEVEALRALTYRACDLYIQGQDVTELASMAKLKAGRLARIVPD
                     ACLQFWGGMGFTWDNPVSRYYRDGRLGSIGGGADEVMLGIICK"
     PFAM_domain     complement(17616..17903)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1491_0078"
                     /evalue="1.70E-26"
                     /label="ctg1_1491"
                     /locus_tag="ctg1_1491"
                     /protein_end="217"
                     /protein_start="121"
                     /score="92.3"
                     /tool="antismash"
                     /translation="CVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNSLQADWM
                     CLLANTSDDPAHRNKSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDV"
     PFAM_domain     complement(17913..18257)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1491_0077"
                     /evalue="4.10E-28"
                     /label="ctg1_1491"
                     /locus_tag="ctg1_1491"
                     /protein_end="118"
                     /protein_start="3"
                     /score="98.4"
                     /tool="antismash"
                     /translation="THEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELG
                     FLGIAKPTEFGGLGLDYSYAMAMAETLGHIHCGGVPMAIGVQTDMATPALARFGSDELR
                     AQFLAPAISGD"
     CDS             complement(18316..19935)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 415.9; E-value: 4.4e-126)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1492"
                     /transl_table=11
                     /translation="MPALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRA
                     RFEQRGQLLPRDRLGRLLDAGAPFLELSTLAGFCLDHADPARSIPGGGFIAGIGWVSGV
                     RAMIIVDDAGIDAGAVQPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVETFIH
                     GGSGFYWLARLSAAGIPVISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKA
                     ATGEIATEEELGGAEMHATTSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYA
                     PPRFDAEELLGIALTDHRKPLDMREVIARFADGSDFLEFKPDYGPGTITGHAAICGMRV
                     GVITNNGPLDPAGATKVVHFIQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTI
                     QAMANATVPRITVHCGASFGAGNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATV
                     MAASMQRKTQTVDHDAIEAMRAKVIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACV
                     LGVCDEARRRTLHPIQFGVARP"
     PFAM_domain     complement(18358..19791)
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1492_0080"
                     /evalue="1.30E-110"
                     /label="ctg1_1492"
                     /locus_tag="ctg1_1492"
                     /protein_end="526"
                     /protein_start="48"
                     /score="370.5"
                     /tool="antismash"
                     /translation="QRGQLLPRDRLGRLLDAGAPFLELSTLAGFCLDHADPARSIPGGG
                     FIAGIGWVSGVRAMIIVDDAGIDAGAVQPMGIEKFQRAQAIALEQKLPFIHLVESAGAN
                     LLTYRVETFIHGGSGFYWLARLSAAGIPVISVVHGSSTAGGAYMPGLSDYVVMVRDRAR
                     AFLAGPPLLKAATGEIATEEELGGAEMHATTSGLAEYLAEDDADALRIARELVAALDWN
                     RDVPAPDRPYAPPRFDAEELLGIALTDHRKPLDMREVIARFADGSDFLEFKPDYGPGTI
                     TGHAAICGMRVGVITNNGPLDPAGATKVVHFIQVCCQSDTPLLYLQNTTGFIVGKASEQ
                     AGMIKHGSKTIQAMANATVPRITVHCGASFGAGNYGMSGRGFFPDFCFSWPNAKTAVMG
                     AEQAAGTMATVMAASMQRKTQTVDHDAIEAMRAKVIDTFERQSDAFTVSGRLLDDGVID
                     PRDTRKVLACVLGVCDEARR"
     CDS             complement(19922..20809)
                     /NRPS_PKS="Domain: PKS_KR (14-125). E-value: 5.9e-12.
                     Score: 37.7. Matches aSDomain:
                     nrpspksdomains_ctg1_1493_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     218; E-value: 2.3e-66)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1493"
                     /transl_table=11
                     /translation="MYRSVFRPGLFQGQVAVVTGGGSGIGRCTAHELASLGAAVALVGR
                     NAEKLAAVRTEIVEAGGTAHAYVCNIRDEAAVQATVAQIYGEHGRIDALVNNAGGQFPS
                     PLKDISAKGWEAVVQTNLTGGFLMARECLNQAMQQRGGAIVNIVADMWGGMPNMGHSGA
                     ARAGMVNFTETAAFEWAQYGVRVNAVAPGYVASSGMDAYPPWMAETIRSMPSTVPLGRF
                     ATEAEVSSAIVYLLSEAAAFITGTTLRVDGGRPNVRPGSPMPAPRHGAEPFNGFHLAVT
                     PKVLQGEEDRHAGA"
     PFAM_domain     complement(20051..20743)
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1493_0081"
                     /evalue="2.70E-54"
                     /label="ctg1_1493"
                     /locus_tag="ctg1_1493"
                     /protein_end="253"
                     /protein_start="22"
                     /score="184.3"
                     /tool="antismash"
                     /translation="SGIGRCTAHELASLGAAVALVGRNAEKLAAVRTEIVEAGGTAHAY
                     VCNIRDEAAVQATVAQIYGEHGRIDALVNNAGGQFPSPLKDISAKGWEAVVQTNLTGGF
                     LMARECLNQAMQQRGGAIVNIVADMWGGMPNMGHSGAARAGMVNFTETAAFEWAQYGVR
                     VNAVAPGYVASSGMDAYPPWMAETIRSMPSTVPLGRFATEAEVSSAIVYLLSEAAAFIT
                     GTTLRVDGG"
     aSDomain        complement(20435..20767)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1493_PKS_KR.1"
                     /evalue="5.90E-12"
                     /label="ctg1_1493_PKS_KR.1"
                     /locus_tag="ctg1_1493"
                     /protein_end="125"
                     /protein_start="14"
                     /score="37.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGGGSGIGRCTAHELASLGAAVALVGRNAEKLAAVRTEIVE
                     AGGTAHAYVCNIRDEAAVQATVAQIYGEHGRIDALVNNAGGQFPSPLKDISAKGWEAVV
                     QTNLTGG"
     CDS_motif       complement(20672..20761)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_1493_0001"
                     /evalue="9.40E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_1493"
                     /protein_end="46"
                     /protein_start="16"
                     /score="18.3"
                     /tool="antismash"
                     /translation="VVTGGGSGIGRCTAHELASLGAAVALVGRN"
     CDS             complement(20831..21985)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 372.6; E-value:
                     3.8e-113)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1494"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.4e-30, bitscore:
                     103.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.4e-24, bitscore:
                     83.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6.2e-46, bitscore:
                     153.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSGLLPSARFDADHDTFRETVRRFVDKAVLPHIDAWEEAETFPR
                     ALYREAADLGLLGIGFPEEYGGTPGDLFLELAMIEELTRAASGGLLASLFSHTIGAPPI
                     VAGGSAELKARVLPAILSGEKISALAITEPSGGSDVASLTTRAVRDGDHYVVSGSKIFI
                     TSGMRADYITVAVRTGEAGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNCR
                     VPVGNLLGAENRGFELVMRNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGKRLVQ
                     HQVARQKLVAMATRIEATRALLEDLMRRMQAGDSPVAQLCMLKNFATQSLQFCADTAVQ
                     LLGGMGFMRGTKSERIYREVKVYMIGGGAEEVLSDLAARQLGWT"
     PFAM_domain     complement(20843..21289)
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1494_0084"
                     /evalue="5.90E-45"
                     /label="ctg1_1494"
                     /locus_tag="ctg1_1494"
                     /protein_end="381"
                     /protein_start="232"
                     /score="153.2"
                     /tool="antismash"
                     /translation="NRGFELVMRNFNHERLALAMQAYGLARTCLIEAVEWATQRETFGK
                     RLVQHQVARQKLVAMATRIEATRALLEDLMRRMQAGDSPVAQLCMLKNFATQSLQFCAD
                     TAVQLLGGMGFMRGTKSERIYREVKVYMIGGGAEEVLSDLAARQL"
     PFAM_domain     complement(21323..21604)
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1494_0083"
                     /evalue="1.70E-23"
                     /label="ctg1_1494"
                     /locus_tag="ctg1_1494"
                     /protein_end="221"
                     /protein_start="127"
                     /score="82.7"
                     /tool="antismash"
                     /translation="ALAITEPSGGSDVASLTTRAVRDGDHYVVSGSKIFITSGMRADYI
                     TVAVRTGEAGAGGISVLLVEGDTPGLSRTPLKKMGWWCSDTAQLHFDNC"
     PFAM_domain     complement(21614..21946)
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1494_0082"
                     /evalue="2.50E-30"
                     /label="ctg1_1494"
                     /locus_tag="ctg1_1494"
                     /protein_end="124"
                     /protein_start="13"
                     /score="105.5"
                     /tool="antismash"
                     /translation="DHDTFRETVRRFVDKAVLPHIDAWEEAETFPRALYREAADLGLLG
                     IGFPEEYGGTPGDLFLELAMIEELTRAASGGLLASLFSHTIGAPPIVAGGSAELKARVL
                     PAILSGE"
     CDS             complement(22000..23772)
                     /locus_tag="ctg1_1495"
                     /transl_table=11
                     /translation="MRNDTVSIGGASGFWGDSVTGPLQLVASGRLDFLVFDYLAELTMS
                     LLASARMKNAELGYATDFVSVAMRAVLKDALAQNIRIIANAGGVNPRGCAAALQALAAE
                     LGVSVRIAVVEGDDVMALLPALRGEGVRELQSARPLPDKVVSANAYLGALPIKAALDAG
                     AQVVITGRCVDSAVTLGALMHAFEWRADDYDRLAAGSLAGHILECGCQGAGGLHTDWEA
                     VPDWAHSGYPIAECRADGSFIVTKPDGTGGLVTTATVGEQLLYEIGDPARYVLPDVVCD
                     FTHVTMTLAGEHRVEVRGARGRAPTPDYKVSATYADGYRATGQLTIVGIDADRKARHTA
                     EAILERTRGLFRQLGLPDYSATHIETLGSAYLFGPHQPNVPRFESVMWLAVTHPNKQAL
                     DLFAREIAPAGTSWAPGTTGAGGRPSVVPAIKQYAFLIDKARVQARVTLLGEEGFDIAV
                     PTGGAALEPSAAAQGSLALPPGPTREVSLIELAYARSGDKGDTSNIGVIARRPEDLPLL
                     RAQLTEDAVAAYLAHVVKGRVTRYDLPGIHALNFVCEQALGGGGMASLRNDPLGKGMAQ
                     VLLTMPVRVPVNHP"
     PFAM_domain     complement(22729..23751)
                     /aSDomain="AtuA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07287.13"
                     /description="Acyclic terpene utilisation family protein
                     AtuA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1495_0085"
                     /evalue="1.10E-120"
                     /label="ctg1_1495"
                     /locus_tag="ctg1_1495"
                     /protein_end="348"
                     /protein_start="7"
                     /score="402.7"
                     /tool="antismash"
                     /translation="IGGASGFWGDSVTGPLQLVASGRLDFLVFDYLAELTMSLLASARM
                     KNAELGYATDFVSVAMRAVLKDALAQNIRIIANAGGVNPRGCAAALQALAAELGVSVRI
                     AVVEGDDVMALLPALRGEGVRELQSARPLPDKVVSANAYLGALPIKAALDAGAQVVITG
                     RCVDSAVTLGALMHAFEWRADDYDRLAAGSLAGHILECGCQGAGGLHTDWEAVPDWAHS
                     GYPIAECRADGSFIVTKPDGTGGLVTTATVGEQLLYEIGDPARYVLPDVVCDFTHVTMT
                     LAGEHRVEVRGARGRAPTPDYKVSATYADGYRATGQLTIVGIDADRKARHTAEAILERT
                     R"
     CDS             complement(23774..24553)
                     /NRPS_PKS="Domain: ECH (15-251). E-value: 4.8e-48. Score:
                     155.4. Matches aSDomain: nrpspksdomains_ctg1_1496_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 211.2; E-value:
                     2.3e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1496"
                     /transl_table=11
                     /translation="VSTDPELLIERRGQALWLTIQREDRRNAINAAVLEALTAALVDAG
                     RDAAVRAVVLTGTGTRAFCAGADLQTGQSFRFDYSQPYQALADLFRQARRCTVPLIARV
                     NGACMAGGMGLLAMCDLAVASHSATFGLPEVKVGVFPAQVLAVLQHQLPRRVLNELCLT
                     GEPMNADRALAAGLVNEVTEPEALDGAVDALLARLVDKSPSAIRRGLYTLKHVESLSFE
                     QAMAFTESQIGLFALTEDAQEGQAAFREKRAPNWRGR"
     PFAM_domain     complement(23780..24505)
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1496_0086"
                     /evalue="5.50E-51"
                     /label="ctg1_1496"
                     /locus_tag="ctg1_1496"
                     /protein_end="258"
                     /protein_start="16"
                     /score="173.4"
                     /tool="antismash"
                     /translation="WLTIQREDRRNAINAAVLEALTAALVDAGRDAAVRAVVLTGTGTR
                     AFCAGADLQTGQSFRFDYSQPYQALADLFRQARRCTVPLIARVNGACMAGGMGLLAMCD
                     LAVASHSATFGLPEVKVGVFPAQVLAVLQHQLPRRVLNELCLTGEPMNADRALAAGLVN
                     EVTEPEALDGAVDALLARLVDKSPSAIRRGLYTLKHVESLSFEQAMAFTESQIGLFALT
                     EDAQEGQAAFREKRAPNWRG"
     aSDomain        complement(23801..24508)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_1496_ECH.1"
                     /evalue="4.80E-48"
                     /label="ctg1_1496_ECH.1"
                     /locus_tag="ctg1_1496"
                     /protein_end="251"
                     /protein_start="15"
                     /score="155.4"
                     /tool="antismash"
                     /translation="LWLTIQREDRRNAINAAVLEALTAALVDAGRDAAVRAVVLTGTGT
                     RAFCAGADLQTGQSFRFDYSQPYQALADLFRQARRCTVPLIARVNGACMAGGMGLLAMC
                     DLAVASHSATFGLPEVKVGVFPAQVLAVLQHQLPRRVLNELCLTGEPMNADRALAAGLV
                     NEVTEPEALDGAVDALLARLVDKSPSAIRRGLYTLKHVESLSFEQAMAFTESQIGLFAL
                     TEDAQEGQAAFREK"
ORIGIN
        1 gacttctcgt cgccgtacgg ctacttcgcc agcacgcgcg tggaggagct cgcccagcgg
       61 tacaaccggg cgacggcatg gcacccgatc ctgctggggg tcgtcttcaa gaccaccggc
      121 ggctccccgc tgcctcaggt gccgctcaag ggcgattacg cgtggcgcga tttcgagcgt
      181 accgcgcgct tcaacggcat tgagtaccgc aagccgacgc acttcccgct gcccacgcaa
      241 tacgccgcgc gggccacgct gtgggtgcat gaccatcacg gcggggaccg cgcgatcgac
      301 ttcgcacggg ccgtctaccg cgcactgttc gttgacgaca tcaacatcgg tgagccgacc
      361 gaggtcatga agattgccga cgcgatgggc atcgacggcg ccgcactcaa cgccggcgca
      421 agcagccagc agatcaagga ccagctcaag gccgagatcg acctggcgat gtcgcgcggc
      481 gtgttcggct cgccctacgt gatcgtcgac ggcgaggcgt tctggggctt cgaccgcttt
      541 gaccagattg aagcgttgct gcgcgacgga cggatataag gccacatcca caacggcggc
      601 agatgcacga accgccgcca acgaaccaac aacgaagagc gcatgactgc agtgacctcc
      661 tctgtttcga accacccgcg ctttgacgcg atcctcttcg attgcgacgg cgtgctggtc
      721 gacagcgaac ccatcgtcaa ccgtttgatc tgggagatgc tgatcgagct tggcatcgac
      781 atcagcctgg aagattccat ccagcgtttc ctcggcaagg ccatccgcga agagctggat
      841 gcgattgccg agatgcgcgg cgcaccgctg ccgccgaact ggttgtccac cttccaggcg
      901 cgacgcaacg tgctgctcga agccgaagtg gaagccgtgc cgcatatcgg gcacgccatc
      961 gatgtgctct ccaggctcgg cctgccgatg gccgtggctt ccggagcgga ccgcatgaag
     1021 gtggagctgc aactcaaccg caccggtctg atcgagcatt tccagccgac ggacgtacgc
     1081 atcttttcgg ccaccgaagt cgcgcgcagc aagcccgcgc ccgacgtgta tctgctcgcc
     1141 gccagcagcc tcggggtatc gccctcgcgc tgcctggtga tcgaagacag ccccacgggc
     1201 gttaccgccg ggcacgcagc cggcatgacg gtgctggcgt acgcgggccg caatgcacca
     1261 ggcccgctga ttgccgccgg cgccacacgc acgttcaccg atatgcgcga actgccggag
     1321 ttgctggcct gatgcctgct gcacaaaccc agcccatcgg cccggccgac gcgtgcccct
     1381 gcggcaacgg cgcctatgcg cgttgctgcg gcccgttcca cgcgggcgag gccgtggcgg
     1441 ctacggctga gcagctcatg cgctcgcgct acagcgctta tgtgctgggc gacacggcct
     1501 acctgcggcg cacgtggcat ccgtccacct gccctgtcga cctggaaacc agcgaagcag
     1561 acgccgccgc cacgcgctgg ctcggcctgg acgtcaggcg ccacacgccg caagacgcca
     1621 cgcacgcgac ggtggaattc gtcgcacgct acaaggtggg cggccgcgcg catcgcctgc
     1681 acgaaaccag ccgcttcgtc cgcctggacg caagcggcgc cgaatccgcc gaaggccgtt
     1741 ggctgtacgt cgacggcacc ttccctgact gaaccgcacc gaccttcccg cactgctgcc
     1801 atgccgacgc tagagaccaa gctgaacccc cgcgctgaag acttcaaggc caacgccgat
     1861 gccatgcgcg cactcgtcgc cgacttgcgc gacaaggttg cgcgcatcgc ccagggcggc
     1921 ggtgacgacg cccgtgccaa acacctcgcc cgcggcaagt tgctgccgcg cgaccgcgtg
     1981 cagcaactgc tcgatcctgg cacgccgttc ctggagttct cgcaactggc ggcgtatggc
     2041 atgtacgaca acgccgcgcc cggcgccggc atcatcaccg gtatcggccg catctcgggg
     2101 caggaatgcg tgatcgtctg caacgacgcc acggtcaagg gcggcaccta ctacccgatg
     2161 accgtgaaga agcacctgcg cgcgcaggag atcgccgagc agaaccacct gccctgcgtc
     2221 tatctggtcg attccggcgg cgccaacctg ccgaaccagg acgacgtgtt ccccgatcga
     2281 gatcacttcg gtcgcatctt ctacaaccag gccaacctgt catcgaaggg cattccacag
     2341 atcgcggtgg tgatgggctc gtgcacggcg ggcggcgcgt atgtgccggc catgagtgat
     2401 gagtcgatca tcgtcaagga acaggggacg atcttcctgg caggcccgcc gctggtgaag
     2461 gccgcgaccg gcgaagtggt gagcgccgaa gacctcggtg gcgccgatgt gcacacgcgg
     2521 ctgtcgggcg tggcggatta cttcgccaac aacgattcgc acgcgttggc gcaagcccgc
     2581 agcatcgtcg cgcacctgaa ccgccgcaag ccggagcagg tgcagattca tgcgcccgtc
     2641 gagccgcgct ttcccgcaga agaactctac ggcgtgatcc cgaccgacac gcgcaagccg
     2701 ttcgacgtgc gcgaggtcat cgcccgcatc gtcgacgatt ccgccttcga tgaattcaag
     2761 gcgcgctacg gcacgacgct ggtctgcggc tttgcgcgca tctggggtta cccggtcggc
     2821 atcatcgcca acaacggcat tcttttttca gaggcggcac tcaagggcgc gcacttcatc
     2881 gagctgtgct gtcagcgcaa gatcccgctg gtgttcctgc agaacatcac cggcttcatg
     2941 gtgggccgca agtacgaaaa cgaaggcatc gccaagaacg gcgcgaaaat ggtgacggcc
     3001 gtggcaacgg cgcaggtgcc caagttcacg gtcatcatcg gcggctcgtt cggcgcgggc
     3061 aattacggca tgtgcggccg ggcgtattcg ccgcgcttcc tgtggatgtg gccgaacgcg
     3121 cgcatctctg tgatgggcgg cgaacaggcc gcaagcgtgc tcgccaccgt gcgccgcgac
     3181 ggcatcgaag ccaagggcgg ccagtggagc gccgatgaag aggccgcgtt caaggcgccg
     3241 atccgcgacc aatatgagcg ccagggccat ccgtactacg ccagcgcacg cctgtgggac
     3301 gacggcgtga tcgaccccgc cgacacgcgc agcgtgctgg gcctcggcct gtcggcgagc
     3361 ctgaacgcgc ccattggcga catgaacttc ggcgtgttcc gcatgtaagc gggccgtcaa
     3421 tcgaacagga atatttgcag tgaacagcaa caccgcgcga acgtggcgca gcgccttggc
     3481 agccgttggc tgcgcgctgc tgcttgcggc cgcgcatgcg agcgaaaccg ctcagtccgg
     3541 catcagcgag atcatcgtgg aggtgcccaa gtctgcgggc atcttcaccc tcaagctgga
     3601 gacgaccgtc tacaagccgg ccggcgacgg cccttttccg ctcatcgtgc tcaatcacgg
     3661 caaggcgcgc ggcaaggcgg cattccaagc gcgtgcccgt tacagcgagc aggctgcggc
     3721 gctggtcgcg cgcggctacg tagtggccat cccgatgcgg caggggttcg ccaaatccgg
     3781 cggcgcgtat atcggcagcg gttgcaacgt ggaagccaac ggcatcatcc aggccgaaga
     3841 cgtggtggcc acgctcgact acatgaccgc gcagccgtac gtggaccgca accgcatcgt
     3901 cgtcatgggc cagtcgcacg gcggcctaac cacgctggcc ttcggtacca tcgcctaccc
     3961 gggcgtgcgc gggctggtga actttgccgg cggcctgcgc aacgacacct gcgtcgattg
     4021 ggaaggcaac ctagtgcgcg cgttcgagac gtacggccgc cagtcgcgct atccgtcgct
     4081 ctggttctac ggcgacaacg acagctactg gcccaagccg atgcccgaca ggatgttcgc
     4141 ggcctacacg agtgcgggcg gaaaaggccg gctggtggat ttcggcacct tcaagagcga
     4201 ctcgcacggc atgttcgcaa gccacgcggg gttgggcatc tggctgccgc aggtcgacgc
     4261 cttcctgcgc gaacttggct tgcccgccgg cccggtgcaa gcggtggcac caggcagcaa
     4321 cgctgaagca tccggcgcag acgaccccaa gtccgacacc aacaaggacc ccgaatgaac
     4381 actttcgaga ccctcgcctt cgcacagaac ggcgccgtcg ccacgctcac gctgaaccgg
     4441 cccgacgtgc gcaacgcctt caacgagacc gtcatcgccg agctgaccgg cgcgttccgc
     4501 gcgctggccg atgagccggg cgtgcgcgcc atcgtcctga cgggcaacgg cccggccttc
     4561 tgcgcgggtg ccgacctgaa ctggatgaag aagatggccg gctactccga tgacgagaac
     4621 cgcgccgacg ccctgcgcct ggccgagatg ctgcgcgcca tctacacctg ccccaagcct
     4681 gtgatcgcgc gcgtgcaggg cgacacgtat gccggcggcg tcggcctggt cgccgcgtgc
     4741 gacatcgtcg ttgccgtgga cacggccaac ttctgcctgt cggaagcgaa gctcggcttg
     4801 atcccggcca ccatcagccc gtacgtgatt cgcgccctgg gcgagcaggc gtcgcgccgc
     4861 tacttcatca ccgcagaacg cttttccgct gccgaagcgc atcgcctcgg cctcgtgcat
     4921 gagctggtga gcgcagacgc cctcgacgcc aaggtggccg acatcaccgc cgcgctcgtc
     4981 gccaacagcc cgaacgcggt gcgcgagagc aagcgcctgg tgcgtgaagt ctctggcgcc
     5041 gccgtcaacg acgccttgct ggcggatacc gctgagcgca tcgccgccat ccgcgcctcg
     5101 gaagaaggcc gcgaaggcgt gcaaagtttt ctgggcaagc gcaagccgaa ctggctgctg
     5161 ccggcctgat ccgcacaaca acgaaaccac gcatcactcg aaggaagtcc tcatgcaatc
     5221 cactccgctc aacttcgttc caaacgctgc caaggcgccc gtcacgcccg gccaggcgcc
     5281 cgacgcacgc tggagccgcg aagccatcga agcactgttc gcgctgccgt tcaacgacct
     5341 gctgttccag gcgcagcagg tgcaccgcgc caactttgac gcgaacgcgg tgcagctatc
     5401 gacgctgctg tcgatcaaga ccggcggctg cccggaagat tgctcgtact gcccgcaatc
     5461 ggcgcgctac gacacgggtg tcgaggctga aaagctgatg ccgatcgacg ccgtgctgga
     5521 agccgcatcg cgcgccaagc aaaacggcgc aagccgcttc tgcatgggcg ccgcgtggcg
     5581 caaccccaag ccgcatcagc tcgatgccgt ggccgacatg gtgcgcggcg tgaaggcgat
     5641 ggggctggag acctgcgtga cgctcggcat gctcaagcag gaacaggccg cgcagttgaa
     5701 ggaagcgggc ctggactact acaaccacaa cctcgacacc gcgcccgagt tctacggcga
     5761 gatcatcacc acgcgcacgt atcaggaccg gctcgacacg ctcgagcacg tgcgtgacgc
     5821 cggcatcaac gtgtgctgcg gcggcatcgt cgggctgggg gaatcggtgc acgagcgtgc
     5881 gggtctgatc gccgaactgg cgaacatgga gccgtatccg gactcggtgc ccatcaacaa
     5941 cctggtgaag gtggaaggca cgccgctggc gggcaacgaa gaactggacc cgtttgattt
     6001 cgtgcgcacg attgccgtgg cgcggatcac gatgcccaag gcgatggtgc ggctctccgc
     6061 tggccgcgag gcgatggacg atgccttgca ggcgctgtgc ttcatggcgg gcgccaactc
     6121 gatcttctat ggcgagaagc tgctgacgac ggataacccg gaggcggatg cggatcggaa
     6181 gctgctggcg cggttgggga tgcgggtgga ggtgcaggat cacatgcacc atgaatcgca
     6241 tgtgggggcg cagtcttcgc attgccatat cgacattacg cccgcggact gatgctttgt
     6301 tgtgggggtg ggtcttggtt tcttgttggt ggtctgcctc cctttcgtcc cctgccgggg
     6361 ccgactcact ttctttgtct tgccaaagaa agtaagcaaa gaaaggcgcg cccgagatgg
     6421 cgaaagattc cttgaattta tgtcgcgggg aggggaaggg aaaaactcgc ttcgctcaga
     6481 cagtttccct tcctttttcc tccctgcaac agaaattcaa ggcgccatct agggcatcaa
     6541 cggccccacc atcgcagtgc aaacgcagtg gtgggtacgc ggcaagacgc ggagcgaagc
     6601 aaacggcaat acagcaacac agcaacaagc aacaagcaac aagcaacaag caagggcctg
     6661 acagagcatg cacaccaacg gtttggccgt tgacgttcct gcccttgatg gcgccttgaa
     6721 ttttcgtaag cgggcggaaa caagacggga aactgtttga gcgcagcgag tttttcccgt
     6781 ctccgcccgg ttacgaaaat tcaagggatg ggtcgccatc tcgggcgcgc ctttcttttg
     6841 cctacttttc tttggcaaga caaagaaaag taggtcgtgc ccggcagggg acgaaacaag
     6901 ggatgcacca caagtgcaaa aacaaacaag gagacgtaac aacaccatga tcaccaagct
     6961 cctcatcgcc aaccgaggcg aaatcgcctg ccgggtcgcc gccacctgcc gcaagctcgg
     7021 catccgcacg gtcgcggtct actccgatgc cgacgccaac gcccgccacg tcgcggcctg
     7081 cgacgaagcc atccacatcg gtgagcccgc cgcccgcgac agctacctcc gcgctgatcg
     7141 catcctcgaa gccgcacgcg ccacgggcgc gcaagccgtc catcccggct acggcttcct
     7201 ctcagagaac gaagctttcg caaaagcctg cgcagacgcc ggcatcatct tcgtcggccc
     7261 gccggcctcg gccatcgaag cgatgggcag caagagcgcg gccaaggcgc tgatggaaac
     7321 ggcgggcgtg ccgctcgtgc ccggctacca cggcgacaac caggacgcgg ccttcctgcg
     7381 cacgcaagcc gatcgcatcg gctaccccgt gctcatcaag gccagcgccg gcggcggggg
     7441 caagggcatg cgcgtggtgg agtcaggcga tgcgttcgaa gcctcgctgg cttccgtcaa
     7501 gcgcgaggcg tcttccagct tcggtgacga ccgcgtactg atcgagaagt acctcacgcg
     7561 tccgcgccac attgaaatcc aggtgtttgc cgacagcttc ggcgacgctg tctatctgtt
     7621 cgagcgcgac tgctctgtgc agcgccgcca ccagaaggtg ctggaagaag cccccgcccc
     7681 gggcatgacg ctggaccgcc gccgcgcgat gggcgaagcg gccgtggcgg ccgcgcgcgc
     7741 cgtgggctac gtgggcgccg gcacggtcga gttcatcgtc gacgaagacg gcacgttcta
     7801 cttcatggag atgaacacgc gcctgcaggt cgagcacccc gtgaccgaaa tgatcacggg
     7861 cgaggacctc gtcgaatggc aattgcgcgt ggcatccggc gagccgctac cacgcacgca
     7921 ggacgagctg cacatccacg gccatgcgct cgaagcacgc atctacgccg aaaaccccga
     7981 ccgcgatttc ctgccctcca tcggcacgct gaaggtgctg cgcacaccag cggcggtgga
     8041 gttcaccgta ggcgcgcaag ccaatggcga accggctgcc gtgcgcatcg atgccggcgt
     8101 gcgtgaaggc gacgccatca gcccgtacta cgatccgatg atcgccaagc tcatcgtctg
     8161 gggccgtgac cgtgaagaag cgctcgcgcg catgctgcag gcgctgggca gcttccacct
     8221 ggtggggctg tcgtccaacg tggctttcct gcgccgcctg gtcgcatcga agccatttgc
     8281 gaccgccgat ctggataccg gcctgatcgc ccgcaatcac gacacgctgt tccccgctgc
     8341 accggacgtg ccgctagacg ccatcgccct ggccgtggct gcgctgctcg cccgcgaggc
     8401 acgcagcctg cgcaccgaca cgcgcgatcc gcattcgccg tgggcgcgcg gcagcggctg
     8461 gcgcctgaac ggcgcggctg agcgcacgct gcgtttcacg catggcgatc agtccatcga
     8521 tgccacgctc atctacggcc gctacggctc gcgactgaaa gttggcggca gcgaagcgcc
     8581 cttcacctca cagcgccatg cagagacctt caccgtcacg ctcggcacgc acaaggcgac
     8641 cggccaggtg catgccgatg gcgacacgtt ccacgtcttc accggcggtg cgcactggac
     8701 gctggagcgc cacgacccgc tcgcccatgc cggcgaggcc gacgacgaag gcggcaagct
     8761 gacggcgccg atgcccggca aggtcatcgc cgtgctggcc gccccggggc aaaccgtcac
     8821 caagggcgca ccgctggtcg tcatggaggc catgaagatg gagcacacgc tcacggcacc
     8881 tgccaacggc gtcgtcgaat ccgtgctgta cggcgtgggc gatcaggtga cggaaggcgt
     8941 gcagttgctg gcgttcaagc ccgccgaatg aagcccaagg gggctgccac acgccttggc
     9001 ggcccctgct acactgcttg acgtatacgt caatcacccg cattgaagtc gccccacatg
     9061 cacatccaga tctacacgcc cgacggcaag ccccaaccct ggctcgacgg tttcgcgcag
     9121 gcacttcctg aggcacgcct gtcggtgtgg gagcaaggcg cagtgcagga cgccgactac
     9181 gccgtggtct ggcagccgcc cgccgacatg ctgcgcgatc gccgcgattt gcgcgccgtg
     9241 ttcaacctcg gcgcgggcgt cgatgccatc ctgggcctgc gtgcgcaagc gcccgatgcc
     9301 atccccgaag gcctgccgat cgtgcggctg gacgacgccg gcatggccgc gcagatgggc
     9361 gaatacgtca cgcacgccgt cctgcgcttc ttccgccggc tcgatgaata cgagcgccag
     9421 cagcaagcga agatgtggcg cttcctcaag ccgttcaacc gcgatgagtt tgtcgtcggc
     9481 gtgctgggcc tcggcgtgct cggtacgcac atcgccagga cgctggcggg cttcggcttt
     9541 ccggtgcgcg gctggagccg ctccgccaag cacgtcgagg gcgtcgattg ccgctcaggc
     9601 agcgatgccc tgcccggctt cctcgccggc acgcgcgtgc tggtgaacgt gctgccgctg
     9661 acggcagaca ccgaaaacgt gatcgacgcg aaactgctcg cgcaactcgc accgggcgcg
     9721 ttcgttgtca acgtggcgcg cggtaagcat gtcgtggaag acgatctgct ggccgccgtg
     9781 cgcagcggcc acattgccgg cgccgcgctc gacgtattcc gcaccgagcc gctgccggcc
     9841 gaccaccctt tctggaccga accgcgcatc cacatcacgc cgcacatttc ggcgctgacg
     9901 ctgcgcgagg tcagcattgc ccagatcgcg cgcaagatcc gagcgctgga agcaggcgag
     9961 ccgattgccg gcatcgtcga tctgcaacga ggttactgag atgagcattc cgaattttgt
    10021 gaaggtggtc gaggtcggcc cgcgcgatgg tctgcagaac gagaagtcgc cagtttcgac
    10081 ggacaccaag gtcgagctgg tgaaccgcct gtccgaggcc ggcttcgtca acgtggaagc
    10141 cgcctcgttc gtgtcgccca aatgggtgcc ggcgatggcc gatggcgccg acgtgatggc
    10201 gcgcatccag cgccggccgg gcacgctgta ctccgtgctc acgcccaaca tgaaaggttt
    10261 cgaaggcgct gctgcagcag gtgcggacga gatcgtgatc ttcagcgccg ccagcgaggc
    10321 ctttgcgcag aagaacatca actgcacgat cgccgagtcg atcgaacgct ttgtgccggt
    10381 ggccaaggcc gccaaggatg cgggcattcg cgtgcgcggg tcgatctcgt gttcgctggg
    10441 ctgcccgtat cagggcgaag tgccggtgtc gtcggtggtg gacgtcatca agcgtatggc
    10501 cgacctcggc tgcgacgaga tcgacattgc cgacaccatc ggcgtgggca ccgcggggcg
    10561 ggtgaaaacc gtgatggaag ccgctgcagc gacgttcccg atcgaccgcc tctcgggaca
    10621 cttccacgac acatacggcc aggcgctggc caacatcctc gccagcctgg aagtcggcat
    10681 cgccatcttc cacgcctcag ttgcggggct gggcggctgc ccgtatgcca agggtgcgac
    10741 cggaaacgtc gccaccgaag atgtgctgta cctgctgcac ggcctgggca tccgcaccgg
    10801 catcgacctg gacaaggtgg tgctggcggg cgacttcatc tcgcaagcca tcggccgccc
    10861 gactgcctcg cgtgcgggtc gcgcgctgct gctcaagctg caggaccaga tcgcccaggc
    10921 ctgcatctga acccccatca agaacaacga cgatgaccgc gaccgatacg aaagctccgt
    10981 tgcctgaatc tgctcaacgc gtggccgacc acctgcgcac gctcggctac gaaaaaaaca
    11041 tcgtgatgct gccggcaacc ggcaagacct ccgctgaagc ggctgccggg ctgggctgct
    11101 ccgtggccga gatcgccaag tcgatcatct tccgccgtgc ggaagacgac gtgccggtgc
    11161 tggtgatcgc cagcggcacc aatcgtgtcg acgaagcaaa ggtttccgcg cacgtgggcg
    11221 cacttgccaa ggccgacgcg aagttcgtcc gcgagaagac cggatacgcc atcggcggcg
    11281 tgtgtccggt cggccatgcg gtcaagccgg tgatgctgct cgaccaagac ctgttccaat
    11341 acgacagctt gtgggccgcg gccggccacc cgcatgccgt gttcaacctg acgcctgccg
    11401 aactggaagc catgaccggc gcgcccgtgg ccgacatcgc ccagcgcgac tgatcgaaca
    11461 catggacgcc tgcacccgcg cgcaattgaa gcgctcgctc ggcaagctgc gcaatagcca
    11521 accgcaggcc gagcgcgccc agccggtggc atcgccgtgc atcagcgtgt gcaagatgga
    11581 cgaagcgcgc ggcctgtgca tcggctgcat gcgcacgatc gacgaaattg cctcgtggtc
    11641 gaccatgaat gacgcggctc gtctggccgt gtggaaaacc ttgcccgagc gcgcctgcgc
    11701 ctggctcaac gacgcgccct gcgcctgacc gctcatcacc atggccgaac acgacgtcgt
    11761 caccttgccc aattcgatgc gcgtgttcga gcgcggctgg ctgtcgtcga acaacatcct
    11821 gtttttcgat gacgaagcgc acggcggttg cgcgctggtc gactccggct acctcacgca
    11881 cgcgccgcaa accgtggcgc ttgtgcagca cgcgctgcga ggcaggccgc tgcgccgtct
    11941 gctgaacacg cacctgcatt ccgaccactg cggcggcaat gcagcgctgc aggccctcta
    12001 cggcagccac acgcgcgtac ccgccgcgca gatcgacgac gtgcgccgct gggataccga
    12061 cgccctcagc tacggcccca ccggccagga atgcgcacgc ttcgcgttgc ctgacagcga
    12121 tgccgacgcg gggctgtcgg acggcatgac ggcccgactg ggaggcttcg actggcaggt
    12181 catcagcgcg ccggggcacg acccgcacgc ggtcattctg ttcagccccg acacgcgcgt
    12241 gctgatttcg gccgacgccc tgtgggaacg tggcttcggc gtgatctttc ccgagctgga
    12301 aggcgagagt ggctttgccg aacagcaggc cattcttgag cgcatcgtgc agctcgatgc
    12361 gctcgtggtg attcccggac acggccggcc gttcaccaac gtcaacgccg cgattgatgc
    12421 atcgctcggg cggcttgcgt atctgcgggc agacccggaa cgcaacgcgc tgcacgccat
    12481 ccgcgtgctg gtgaagttca agctgctgga gcagcaggcg ctgtcgcacg aggcgctgtt
    12541 tgcgtggttc acacagacca cgctgatgcc gcgcttgcac gcacgcttct tcgcagccca
    12601 atcgatggag acgttgctgg atgctgcgat tgcggcgctg gtcaaggcgg gcgccgccac
    12661 cgtcgaacac ggccgcatcc tgaaccgcga ttgacgtgcc gcgcggtggc agtgccccgc
    12721 tacaatgcag cgacgcctct tctcttcgcc tgggcatgcc gaaacccgcc acatccaatc
    12781 cgcccgaatc tgccaccgaa gccgcccctg aagccgaagc accgcgccgc aagcgcggcc
    12841 gccccgcgca ggacgccaac gagggcttgc gccgcgcgct gatcgagcaa tcggcccgac
    12901 tgttccggga gaagggctac ggcaacacca cggtacgcga cattgcggcg gccacgggcg
    12961 tgcatgcggg cagctggttc tactacttca agaccaagca ggacatcctg caagccgtga
    13021 tcgaacatgg tctgaccgtg gcgctggcgg atatcgaagc catcgatatc gaagacctgc
    13081 ccccgcgcga ggcgatgcgc cagctcgtgc gcgcgcacct ccacacgatc cttgcgcccc
    13141 accaggattt cattccggtg atgctgtacg agtggcgctc gctcgacgcg caggcgcaag
    13201 aacgcatcat cgcgctcaag gatcggtatg aagacatctg gacgcgcgtg atcgaccgcc
    13261 tgcgcgcctc cggcgaatgg gcccacccga cgcctgtcga tcggctgctg atgttcggtg
    13321 cgctgaactg gacggcgcag tggtatcagg ccggcgcggg tatcagcatc gatgcactcg
    13381 ccgatcaggc ggtgctgttc atcctgcgta cgccgcctca gccggcggct tagcgttcct
    13441 tagcgggcct cgccctcgaa cagcgtctgg ttggcgctgc gcagcacgtg tttctggatc
    13501 ttgccggtcg ccgtcatggg cagcttgtcg accacggcga tgtgcttggg cacctcaaag
    13561 ctgccgagat gcgcccgaca atgcgcctgc aacgcggcgg catcggcgtg agcatcgggc
    13621 ttgaggcaga cgaatgcggc caccgcttcc acccagtgcg cgtgcggcaa gccgaccact
    13681 gccgcattcg ccacggccgg gtgccgtagc aacacttctt ccaccttgac cgaagggacg
    13741 ttctcgccgc cggtcttgat catgtccttg atgcggtcct tgaactgaag ctggccgtcg
    13801 gcatcccaca tgccgaggtc gcccgtgtgg tgccagccga agcggcgcgc attggccgtg
    13861 gcctgcgggt ccttgtagta gccgagcatg acgttcgggc cgcggtgcac gatctcgccc
    13921 aactggttcg ggccgagcag attgccttga tcgtccatca ccgctgcttc gttcaccatg
    13981 cacggctgcc cccaatagtt gccggtgcgc tgcagttgct ggtcaggcgc gaagtacatc
    14041 gtcatcggaa aaatttcggt ctgcccggag ccgagggcaa agttggggca cacctcggca
    14101 atcaggcgtt cgagcagggg cctggccatc ggcgccatcg catagaggca caggcgcagg
    14161 cttgagagat cgcgctgcgc acgcagcgga tgatgcagca gcgcggcgta catgagcggc
    14221 aagccgaaca gctgcgtgat gcgttcgttg gcaatcacat cgagcagcgc cgccggatca
    14281 aagccgcgct ggatgacaag cgtggcgccc accatcatcg cggacgcggc cgttgcaaac
    14341 tgcgcgcagt ggaacatcgg cagcaggcac gagaacacgt cggtctcatt cagattcagg
    14401 ccggcgacgt tggacatcag cgcggcatgc accgagcggt gcgaatgcat cgcgcccttt
    14461 ggtcggccgg tcgtgccgct ggtgtacatg atgagcgcga gatcgcgatc gtcgatcacc
    14521 acagcgggca gcgtgtccgc gtggccttgc agcgcttgct ccaccggttg cggcccgtcg
    14581 gcaaccggtt caccgaagca ttggtgcgcc gggagcccga gcgtcgccag cgtgtcgcgc
    14641 agcgccgggt acagcgccgc gtcgatcacc acgtgccgcg cctcggcatg ttcgaggatg
    14701 tagcgcacgt cttccggccc gagcatcgcg ttgatcggca cccacaccag tcccgccttg
    14761 agaatgccgt acgcggccac caggaactgc gcagagtttc cacacaccat cgccaccttg
    14821 tcgccgggct tgaggctgct tgcaagcagc gcgtgcgcgt agcgattgct gtctgcgttg
    14881 agttcgccat gcgtcatgcg gcgggcgcca tcgaccagcg cgaccttcgc gccgaacttg
    14941 cgcgcactgc gatgcaacgt atcgcccaac gtcacccggt tcagcaggtt ggcttcaagc
    15001 gcggtgtctg gcgtggcttc ggacatggga cgtctcctgt ggactgcatt gactgcattg
    15061 accgcatgaa cagcacgaca aaacgatgga tcagaccggc aatgcagccg tcaggccgcg
    15121 gcaatctcca tcaacaaccc accgggcgca acctgggcgc cgacctgggt gaacagcccc
    15181 ctcacctcgc ctgcgagcgg cgcggcaatg ctgtgctcca tcttcatcgc ctcgaccacc
    15241 agcagcacct gaccggcgca aacggcctcg ccttcggcca cgtgtacggc aaccacgcga
    15301 ccgttcatcg gtgcgctgat gcggccgctg ccagtttgtg cgccgctgcg ctccgccttg
    15361 gcgtaggtgg tgtcgatggc ggtgtgttcg atgccattca gcacgaagtg gcaagcgctg
    15421 gccgtgacgg cgtaatccac cgcgtggaat gcgtcgccca gcgcgagcgt gacgcgaccg
    15481 tcgcccgccg acacaaccgc cacctgcgtg gccccgccgt cccaggccag ctcccattgc
    15541 tgcgcaccga gcgcacgcac gcgcatgtcg atggcttcac cgtcgagcgt gaagcggcac
    15601 agcgtgggat acgtgcggct gctggcccag ccatgcagct ctgcgggata gcggcgtgcg
    15661 gtgtcctggc gcaggtacgt gagcagcacg gcagccgctt ggcaaaccgc tgcatcgggt
    15721 acggccgcct gacgcatcgc cgccgggaaa tgccggtcga tgaacgcggt cgacacatcg
    15781 ccggaaagga acgccggatg cgccacgcaa tcgcgcaaaa acgcccggtt ggtcggcaag
    15841 ccaagcagca ggcaatcgtc cagggcgtgc gcgagacgcc ggcatgcatc ggcgcggtcg
    15901 gtgccgtgcg cgacgatctt ggcgagcatc gaatcgtagt acggcgagac aaccagcccg
    15961 tcggccaacg catggtccgt gcgcacgtct ccgggtgcac gccagcgcgc gacggtgccg
    16021 ctttgcggca ggaaattctg ctgcgggtct tctgcgcaca gacgcacttc gatggcgtgg
    16081 ccgccttgtg cacggcgggc gtcgatggcg tcttgcgcaa gcggcaacgg ctcgcccagc
    16141 gccacgcgca actgccactc gaccagatcg acgcccacga tcgcttcggt caccgcatgc
    16201 tcgacctgca ggcgcgtgtt catctccatg aagtagaacg cgccgtccgg ggcgagcagg
    16261 aattccagcg tgcccgcacc cacgtagccg atcgcgcgcg ccgccgccac cgacaccgcg
    16321 cccatgcgcg cgcgcaactc gggcgacacg gccggcgacg gcgactcctc aattaccttc
    16381 tgatgccggc gctgcaccga gcaatcgcgc tccccgaggt ggaccacatt gccgtgcgca
    16441 tcggcaaata cctgaatctc gatgtggcgc ggctcgacga tagctttctc gaggatcaac
    16501 tcgcccgagc caaacgcgtt ctccgcttcg gagcgggcag actgcagcgc cgccgcaaac
    16561 gcctcgggcc ggtctacacg ccgcatgccg cgcccaccgc cgccggcggc cgccttgatc
    16621 atcaccgggt agccgatgcg cgccgcttcg tccgccatgc gtgtggcgga ttggtcctcg
    16681 ccctgataac cgggcacgca cggcacgccg gccgcttcca tgaggcgctt ggcgccagcc
    16741 ttgttgccca tcgctcggat ggcccccgca ggcggcccga tgaagacgag gccggcatcc
    16801 gcgcatgcgc cggcaaaggc atcgctctct gcaaggaagc cgtaacccgg atggaccgcc
    16861 tgcgcacccg acttgcgcgc ggcctccagc aacgccgcaa cgttcaggta cgacgcctgc
    16921 ggttgcgacg cgccgatcgg caacgccaga tcggccgcgc ggcaatgcgg cgcatcgcgg
    16981 tcagcgtcgg aatacacggc aacggtgggc atgccaaggc gacgcgccgt gcgcatgatg
    17041 cgcaaagcga tctcgccccg gttggcgatg aggatcgagc ggaaggcggc atgcggggcg
    17101 gtcatctttc agcccttctt gcccggcagc gtgttcatgt acttgcagat gatgccgagc
    17161 atcacctcgt ccgcaccgcc gccaatcgag cccaggcgcc cgtcgcggta atagcgcgag
    17221 accgggttgt cccacgtgaa gcccatgccg ccccagaact gcaggcaggc atcaggcacg
    17281 atgcgcgcga ggcgcccggc cttgagcttg gccatcgatg ccagctccgt cacgtcctgc
    17341 ccttggatgt acagatcgca cgcgcgatac gtgagcgcac gcagcgcttc cacttccgtc
    17401 ttcagctcgg ccagcttgaa gtgcacccac tggttgtcga gcaggctggc gccgaagagc
    17461 ttgcgctcgc gtgcgtactc ggcggtggtc tcgatgcaca tcgtcatcgt cgccaggctg
    17521 ctggccgcgg cccacaggcg ctcttcctgg aattgcagca tctggtacgt gaagcccttg
    17581 ccttcctcgc cgatgcgata gcgctgtggc acgcgcacat cgtcaaaata gatgaggccc
    17641 gtgtccgacg aattcatgcc gatcttgcgg atcttcttgc cgaccgacac gcccttcgtg
    17701 ttcatcggca cgatgatgag cgacttgttg cggtgggcgg ggtcgtccga cgtgttggcc
    17761 agcaagcaca tccagtcggc ctgtaggctg ttggtgatcc acatcttgct gccgttgatg
    17821 atgtagtcgt cgccgtcctt gcgcgccgtg gtcttgatgc ttgccacatc ggagccagcg
    17881 ctcggctccg atacgccaac gcacgccacc gcatcgccgc tgatggcggg ggcgagaaac
    17941 tgtgcgcgca gctcgtccga accgaagcgt gcgagcgcgg gcgtcgccat gtcggtctgc
    18001 acgccaatcg ccatcggcac gccgccgcag tggatgtgcc ccagcgtctc ggccatcgcc
    18061 atcgcatacg aatagtcgag ccccaggccg ccaaactcgg tcggcttggc gatgccgaga
    18121 aagcccaact cgcccatctt cttgaagagc tgcttggcgg gaaacatctc cgccgcttcc
    18181 cattcatcga cgtacgggtt gatgtcgctg tcgatgaagc gtttcaggtt gcgctgcagt
    18241 tcctggtgct cgtgggtgaa gtgcatggtg tctcgctccg gttgtcctgg gctgttcgtg
    18301 tatgggtcgg gatggctacg ggcgcgcaac gccaaactgg atcggatgca acgtgcggcg
    18361 gcgcgcttcg tcgcacaccc cgagcacgca ggccagcacc ttgcgtgtgt cgcgcgggtc
    18421 gatcacgccg tcgtccagca atcggcccga aacggtgaat gcatcggact gccgctcgaa
    18481 cgtgtcgatc accttggcgc gcatcgcttc aatggcgtca tggtcgacgg tctgcgtctt
    18541 gcgttgcatg ctcgcggcca tgaccgtcgc catcgttccg gcggcctgct cggcgcccat
    18601 cacagccgtc ttggcgttgg gccagctgaa gcaaaaatcc ggaaagaagc cgcgccccga
    18661 catgccgtag ttgcccgcgc caaacgacgc gccgcaatgc acggtgatgc gcggcacggt
    18721 ggcgttggcc atggcctgga tcgtcttcga gccgtgcttg atcatgccgg cctgttccga
    18781 cgccttgccg acgatgaaac cggtggtgtt ttgcagatac agcagcggcg tgtcggactg
    18841 gcagcacacc tgaatgaaat gcaccacctt ggtcgcgccc gccgggtcca gcggcccgtt
    18901 gtttgtgatg acgccgacgc gcatgccaca gatggccgca tgccccgtga tcgtgccggg
    18961 gccatagtca ggcttgaact ccagaaaatc cgatccatcg gcaaagcgtg caatgacctc
    19021 gcgcatgtcc agcggtttgc gatgatcggt cagcgcaatg ccaagcagtt cttctgcatc
    19081 gaagcgcggc ggcgcatagg gcctgtccgg tgccggcaca tcgcggttcc agtcgagcgc
    19141 ggccacaagt tcgcgcgcga tgcgcagtgc atccgcatcg tcttcggcca ggtattcggc
    19201 caggcccgaa gtggtggcgt gcatctccgc accgcccagt tcctcttcgg tggcgatctc
    19261 gcccgtggcc gctttcagca acggcggccc ggcgaggaac gcgcgcgccc ggtcgcgcac
    19321 catcaccacg tagtccgaca ggcccggcat gtaggcgccg cccgccgtgc tggacccatg
    19381 caccacgctg atcaccggaa tgcccgccgc cgacagccgc gcgagccagt aaaagccgct
    19441 gccgccgtgg atgaaggtct ccacgcgata cgtcagcagg ttggcgccgg ccgattcgac
    19501 aaggtggatg aacggcagct tctgctccag cgcaatggcc tgggcacgct ggaacttctc
    19561 gatgcccatc ggctgcacgg cccctgcgtc gatgcccgcg tcgtcgacaa tgatcatcgc
    19621 gcgcacaccg ctcacccagc cgatgcccgc gatgaagccg ccgccaggaa tcgagcgcgc
    19681 cgggtctgcg tggtcgaggc aaaagcccgc cagcgtggat agctcaagaa acggcgcgcc
    19741 ggcgtcgagc aggcggccaa gccggtcgcg cggcaggagt tgaccgcgct gctcgaagcg
    19801 ggcgcgcgag gcttcggact tgtcgcgtgt gcgatcttcc aacgtgcgca accggccgac
    19861 gagttccgtg agcgcggcat ggttctgccg atacgcgtcg ctctgcggca cgatgcgcga
    19921 ttcaagcgcc ggcatggcgg tcctcctcgc cttgcagcac cttgggcgtc acggccaggt
    19981 ggaagccgtt gaacggctcg gcaccatgac gcggagccgg catgggcgaa ccgggccgca
    20041 cgttcgggcg gccgccgtcc acgcgcaacg tcgtgccggt aatgaatgcc gcggcttccg
    20101 agagcagata cacgatggcc gaagacactt ccgcctcggt ggcaaagcgc ccgagcggca
    20161 ccgtcgacgg catgctgcgg atggtctcgg ccatccacgg cggatacgca tccatgcccg
    20221 acgacgcgac gtagcccggc gctaccgcgt tcacgcgcac gccgtattgc gcccactcga
    20281 atgcggccgt ctccgtaaag ttcaccatgc ccgcccgcgc ggcgccggag tggcccatgt
    20341 tgggcatgcc gccccacatg tccgccacga tattgacgat ggcgccgccg cgctgctgca
    20401 tcgcctggtt gaggcactcg cgcgccatca ggaagccgcc ggtcaggttc gtctgcacga
    20461 cggcttccca gcccttggcg gaaatgtcct tgagcggcga gggaaactgc ccgcccgcgt
    20521 tgttgacgag cgcgtcgatg cggccgtgct cgccgtagat ttgcgcgacg gtggcttgca
    20581 cggcagcctc gtcgcggatg ttgcagacgt aggcgtgcgc ggtgccgccc gcttcaacga
    20641 tctccgtgcg cacggcggcg agcttctctg cgttgcgccc caccaacgcg accgccgcac
    20701 ccagcgacgc caactcatgc gcagtacacc ggccgatgcc gctgccgcca cccgtcacca
    20761 cggccacctg cccctggaac agccccggtc gaaagactga gcgatacatg gttctctccc
    20821 tgaatgcgcg ttaggtccag ccgagttggc gcgcggcaag gtcgctgaga acttcctccg
    20881 cgccgccgcc gatcatgtag accttcactt cacgatagat gcgctccgac ttggtgccgc
    20941 gcatgaagcc cataccgcca agcagttgca cggccgtgtc cgcgcagaac tgcaagctct
    21001 gcgttgcgaa atttttcagc atgcacagct gcgcgaccgg agaatcgccg gcctgcatgc
    21061 gccgcatcag gtcttccagc aacgcccggg tggcttcgat gcgcgtggcc atcgccacca
    21121 gcttctggcg cgccacctgg tgctgcacga ggcgcttgcc gaaggtctcg cgctgggtgg
    21181 cccattccac ggcttcgatc agacacgtgc gcgccaggcc gtaggcctgc atcgccagcg
    21241 cgaggcgttc gtggttgaag ttgcgcatca ccagctcgaa accgcggttt tccgcgccga
    21301 gcaggttgcc gaccggcacg cggcagttgt cgaaatgcag ttgcgccgtg tcagagcacc
    21361 accagcccat cttcttgagc ggcgtgcgcg acagcccagg cgtatcgccc tccaccagca
    21421 gcacggagat gccgcccgcg cccgcctcgc cggtgcgcac ggccacggtg atgtaatcgg
    21481 cgcgcatgcc ggaggtgatg aagatcttgc tgccggagac gacgtagtga tcgccgtcgc
    21541 gcaccgcgcg tgtggtgagg ctggcgacat ccgagccgcc cgaaggctcg gtgatggcaa
    21601 gcgcgctgat cttctcgccc gacagaatcg ccggcaacac gcgcgccttc agctcggccg
    21661 atccgcccgc cacgatgggc ggcgcaccga tcgtatggct gaacagcgat gcgagtagac
    21721 cgccgctggc cgctcgcgtc agctcttcga tcatcgccag ttcaagaaac aggtcgcccg
    21781 gcgtgccacc gtattcctcg gggaaaccaa tgccgagcaa gccaaggtcg gccgcttcgc
    21841 gatacagcgc acgcggaaac gtctcggcct cttcccacgc atcgatgtgc ggcagcacgg
    21901 ccttgtcgac aaagcggcgc accgtctcgc gaaaggtatc gtgatcggca tcgaagcggg
    21961 cagacgggag caaacctgaa agcatgatcg cctcgtcaat caagggtggt tgaccggcac
    22021 gcgcaccggc atcgtcagca gcacctgcgc catgcccttg ccgagcggat cattgcgcag
    22081 cgatgccatg ccgccaccgc ccaacgcctg ttcgcacacg aaattgagcg cgtggatgcc
    22141 gggcaagtcg taccgcgtca cgcgcccttt cacgacgtgc gcgaggtacg ccgcgacggc
    22201 atcttccgtc agttgcgcgc gcagcagcgg caggtcttcg ggccgacgcg cgatgacgcc
    22261 gatattggaa gtgtcgccct tgtcgccgct gcgggcatag gcgagttcga tgagagacac
    22321 ctcgcgcgtc gggccgggag gcaatgcaag ggagccctgc gccgcagcgg atggttcaag
    22381 cgcggcgcca cccgttggca cggcaatgtc gaagccctcc tcacccagca acgtcacgcg
    22441 cgcctggacg cgtgccttgt cgatcaaaaa agcgtattgc ttgatggccg gcaccacgct
    22501 gggccgcccg ccggcgccag tcgtgccggg cgcccacgac gtgccggccg gggcgatctc
    22561 gcgcgcgaac aggtccaatg cctgcttgtt cggatgcgtc accgccagcc acatcaccga
    22621 ttcgaaacgg ggcacgttcg gctgatgcgg cccgaacaga tacgccgacc cgagcgtctc
    22681 gatatgcgtt gcgctgtagt ccggcagacc gagctggcgg aacaggccgc gcgtgcgctc
    22741 cagaatcgcc tcggctgtgt ggcgcgcctt gcggtcggcg tcgatgccga caatggtgag
    22801 ctgaccggtc gcgcgatagc catcggcata cgttgcgctc accttgtaat cgggcgtggg
    22861 cgcacgaccg cgtgcgccgc gcacttccac gcgatgctcg ccggccagcg tcatcgtcac
    22921 gtgcgtgaag tcgcaaacga cgtcgggcaa cacatagcgc gcggggtcgc cgatttcgta
    22981 gagcagttgt tcgcccacgg tcgcagtcgt caccagcccg cccgtgccgt cgggcttggt
    23041 gacgatgaag ctgccgtcgg cccggcattc ggcgatcggg tagccgctgt gcgcccagtc
    23101 gggcacggct tcccaatcgg tgtgcagacc gcccgcaccc tggcagccgc actcaaggat
    23161 gtgcccggcg aggctgccgg cggcgagccg atcgtagtcg tcggcacgcc actcgaacgc
    23221 gtgcatcaag gcgcccaggg taaccgcgct atcgacacag cggccagtga tgaccacctg
    23281 cgcgccggca tcgagcgccg ctttgatcgg caacgcaccg aggtacgcgt tggcactcac
    23341 caccttgtcg ggcaatgggc gtgcgctctg tagttcgcgc acgccttcgc cgcgcaaggc
    23401 aggcagcagc gccatgacat cgtcgccttc caccacggca atgcgcacgc tcacgcccaa
    23461 ctcagcggcc aaggcttgca gcgccgccgc acatccgcgt gggttcacgc cccccgcgtt
    23521 ggcgatgatg cggatgttct gcgccagcgc atccttgagc accgcgcgca tcgccacgct
    23581 cacaaagtcg gtggcgtaac ccaactcagc gttcttcatg cgcgcgctgg ccagcaacga
    23641 catggtcagc tcggccaggt aatcgaagac gaggaagtcg agacggccgg aggccaccag
    23701 ctgcagcggc ccggtcacgc tgtcgcccca gaagccgctg gccccgccga tggaaacggt
    23761 gtcattgcgc atgtcagcgg cccctccagt tcggggcgcg cttttcgcga aaggcggctt
    23821 ggccttcctg cgcgtcttcg gtcaacgcaa acagaccgat ctggctttcg gtaaaggcca
    23881 tggcctgctc gaagctgagc gattccacgt gcttgagcgt gtacaggccg cgccggatgg
    23941 ccgacggcga tttgtcgacc agccgcgcaa gcaatgcatc gacagcccca tcaagcgctt
    24001 cgggctcggt gacttcgttg acgaggccag cggcgagcgc gcggtctgcg ttcatcggtt
    24061 cgcccgtcaa gcacaactcg ttcagcacgc ggcgtggcaa ctggtgctgc agcacggcca
    24121 gcacctgggc gggaaacacg ccgaccttca cctccggcaa gccgaacgtg gcgctgtggc
    24181 ttgccaccgc cagatcgcac atcgccagca aacccatgcc gcccgccatg caagcgccat
    24241 tcacgcgggc gatgagcggc acggtgcagc ggcgcgcctg gcgaaacaga tccgccaggg
    24301 cttggtacgg ctgggaatag tcgaagcgga aggactgtcc ggtctgcaga tcggcgccgg
    24361 cacagaaggc acgcgtgccg gtgccggtca gcaccacggc ccgcacggcg gcgtcacggc
    24421 cggcgtcgac cagcgcggca gtcagcgctt ccagcacggc ggcgttgatc gcgttgcggc
    24481 ggtcttcgcg ctggatggtc agccacagcg cttggccgcg ccgctcgatg aggagttccg
    24541 ggtccgtgct cacgcgacgc tcgccttgaa agggaattcg gttggacagc ctgcccggca
    24601 atactaaatc atttgattga aaaaatggaa gcgttcgcgt gctgtgggtc ctcaacgatt
    24661 ttctacagcg aagccggatc gtcataaccc catgatttat atgacgatcc cactgcggcc
    24721 gtaagcaatt cgccagccga cgcgttgact cgctcacatt tgaacgataa caattctcat
    24781 ttacaaaaaa catgtggcaa aaactttcag gggagtgtca ccacgtcatg tccgcagcac
    24841 agatcgaacg caagcgcacc gaacattcgg tggtgggtta tctgaccggc gcgatgagct
    24901 tcgccgtggt ttcggcgccg gcactggccg acacgaagaa agacgccgtg tccgccaccc
    24961 tgcccgagca aaccgtcacc ggcaccaacg ggttcaaggc ggatgcggcc tcgggcggca
    25021 aattca
//
