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Overview
1.1
1.2
1.3
2.1
3.1
3.2
3.3

### Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_CABK.. (original name was: NZ_CABKQE010000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene,redox-cofactor | 1,357,855 | 1,399,255 | APE Vf | Other | 10%
Region 1.2 | siderophore | 1,499,219 | 1,511,186 |
Region 1.3 | betalactone | 1,554,572 | 1,579,597 |

c00002_NZ_CABK.. (original name was: NZ_CABKQE010000002.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | RiPP-like | 1,115,172 | 1,126,041 |

c00003_NZ_CABK.. (original name was: NZ_CABKQE010000003.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | terpene | 1 | 16,617 |
Region 3.2 | T1PKS | 101,729 | 149,399 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 11%
Region 3.3 | redox-cofactor | 615,549 | 637,686 | lankacidin C | NRP + Polyketide | 13%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene,redox-cofactor | 1,357,855 | 1,399,255 | APE Vf | Other | 10%
Region 1.2 | siderophore | 1,499,219 | 1,511,186 |
Region 1.3 | betalactone | 1,554,572 | 1,579,597 |
Region 2.1 | RiPP-like | 1,115,172 | 1,126,041 |
Region 3.1 | terpene | 1 | 16,617 |
Region 3.2 | T1PKS | 101,729 | 149,399 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 11%
Region 3.3 | redox-cofactor | 615,549 | 637,686 | lankacidin C | NRP + Polyketide | 13%

No secondary metabolite regions were found in these records:
  c00004_NZ_CABK.. (original name was: NZ_CABKQE010000004.1)
  c00005_NZ_CABK.. (original name was: NZ_CABKQE010000005.1)
  c00006_NZ_CABK.. (original name was: NZ_CABKQE010000006.1)
  c00007_NZ_CABK.. (original name was: NZ_CABKQE010000007.1)
  c00008_NZ_CABK.. (original name was: NZ_CABKQE010000008.1)
  c00009_NZ_CABK.. (original name was: NZ_CABKQE010000009.1)
  c00010_NZ_CABK.. (original name was: NZ_CABKQE010000010.1)
  c00011_NZ_CABK.. (original name was: NZ_CABKQE010000011.1)
  c00012_NZ_CABK.. (original name was: NZ_CABKQE010000012.1)
  c00013_NZ_CABK.. (original name was: NZ_CABKQE010000013.1)
  c00014_NZ_CABK.. (original name was: NZ_CABKQE010000014.1)
  c00015_NZ_CABK.. (original name was: NZ_CABKQE010000015.1)
  c00016_NZ_CABK.. (original name was: NZ_CABKQE010000016.1)
  c00017_NZ_CABK.. (original name was: NZ_CABKQE010000017.1)

Compact view
c00001_NZ_CABK.. - Region 1 - arylpolyene,redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,357,855 - 1,399,255 nt. (total: 41,401 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0002008.1 |  |  | 0.37 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000928.1 |  |  | 0.34 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  |  | 0.34 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0001589.1 |  |  | 0.34 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001588.1 |  |  | 0.33 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0000883.1 |  |  | 0.32 | Other | arginomycin | Streptomyces arginensis
BGC0001120.1 |  |  | 0.32 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001917.1 |  |  | 0.31 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000255.1 |  |  | 0.29 | Polyketide | pederin | Uncultured bacterium
BGC0000700.1 |  |  | 0.29 | Saccharide | istamycin | Streptomyces tenjimariensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.62 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000838.1 |  | 0.55 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000343.1 |  | 0.53 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001897.1 |  | 0.52 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000255.1 |  | 0.52 | Polyketide | pederin | Uncultured bacterium
BGC0000260.1 |  | 0.50 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0001292.1 |  | 0.50 | Other | A33853 | Streptomyces sp. NRRL 12068
BGC0000700.1 |  | 0.50 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0002000.1 |  | 0.50 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000722.1 |  | 0.49 | Other (Cyclitol), Polyketide | validamycin A | Streptomyces hygroscopicus subsp. jinggangensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_CABK.. - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,499,219 - 1,511,186 nt. (total: 11,968 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.18 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001408.1 |  | 0.15 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0001919.1 |  | 0.03 | NRP, Polyketide | neoantimycin | Streptomyces orinoci

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.50 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001408.1 |  | 0.46 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0001919.1 |  | 0.16 | NRP, Polyketide | neoantimycin | Streptomyces orinoci

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00001_NZ_CABK.. - Region 3 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,554,572 - 1,579,597 nt. (total: 25,026 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.28 | Other | showdomycin | Streptomyces showdoensis
BGC0001983.1 |  | 0.22 | Other | triacsins | Kitasatospora aureofaciens
BGC0000234.1 |  | 0.21 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000261.1 |  | 0.21 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000886.1 |  | 0.20 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0001730.1 |  | 0.20 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000258.1 |  | 0.20 | Polyketide | prodigiosin | Serratia sp.
BGC0000891.1 |  | 0.19 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1 |  | 0.19 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.19 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001778.1 |  | 0.61 | Other | showdomycin | Streptomyces showdoensis
BGC0001983.1 |  | 0.55 | Other | triacsins | Kitasatospora aureofaciens
BGC0000234.1 |  | 0.54 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000261.1 |  | 0.54 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000886.1 |  | 0.53 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0001730.1 |  | 0.52 | Polyketide | paramagnetoquinone 1, paramagnetoquinone 2 | Actinoallomurus sp.
BGC0000258.1 |  | 0.52 | Polyketide | prodigiosin | Serratia sp.
BGC0000891.1 |  | 0.51 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000890.1 |  | 0.51 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0001465.1 |  | 0.51 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00002_NZ_CABK.. - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,115,172 - 1,126,041 nt. (total: 10,870 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.18 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000783.1 |  | 0.14 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000774.1 |  | 0.14 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0001312.1 |  | 0.06 | NRP | viscosin | Pseudomonas fluorescens SBW25
BGC0000721.1 |  | 0.06 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000133.1 |  | 0.04 | Polyketide | quartromicin A1 | Amycolatopsis orientalis
BGC0000144.1 |  | 0.04 | Polyketide | salinomycin | Streptomyces albus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.49 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000783.1 |  | 0.44 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000774.1 |  | 0.43 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0001312.1 |  | 0.27 | NRP | viscosin | Pseudomonas fluorescens SBW25
BGC0000721.1 |  | 0.26 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000133.1 |  | 0.20 | Polyketide | quartromicin A1 | Amycolatopsis orientalis
BGC0000144.1 |  | 0.17 | Polyketide | salinomycin | Streptomyces albus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABK.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 16,617 nt. (total: 16,617 nt) Show pHMM detection rules used
Region on contig edge.
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.18 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000643.1 |  | 0.18 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.18 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000630.1 |  | 0.15 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000527.1 |  | 0.15 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000515.1 |  | 0.14 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001727.1 |  | 0.13 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000928.1 |  | 0.13 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.13 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0000642.1 |  | 0.12 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.50 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000643.1 |  | 0.50 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000634.1 |  | 0.49 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000630.1 |  | 0.46 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000527.1 |  | 0.45 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000515.1 |  | 0.43 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001727.1 |  | 0.41 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000928.1 |  | 0.41 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.41 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0000642.1 |  | 0.39 | Terpene | carotenoid | Enterobacteriaceae bacterium DC413

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_CABK.. - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 101,729 - 149,399 nt. (total: 47,671 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.31 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001697.1 |  | 0.31 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001067.1 |  | 0.31 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001913.1 |  | 0.29 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0001124.1 |  | 0.28 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001749.1 |  | 0.28 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0001340.1 |  | 0.28 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0000046.1 |  | 0.27 | Polyketide | depudecin | Alternaria brassicicola
BGC0000800.1 |  | 0.25 | Saccharide | xanthan | Xanthomonas campestris
BGC0001504.1 |  | 0.25 | Polyketide | amycomicin | Amycolatopsis sp. AA4

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.65 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001697.1 |  | 0.65 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001067.1 |  | 0.64 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001913.1 |  | 0.62 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0001124.1 |  | 0.62 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001749.1 |  | 0.62 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0001340.1 |  | 0.62 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0000046.1 |  | 0.61 | Polyketide | depudecin | Alternaria brassicicola
BGC0000800.1 |  | 0.59 | Saccharide | xanthan | Xanthomonas campestris
BGC0001504.1 |  | 0.59 | Polyketide | amycomicin | Amycolatopsis sp. AA4

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 101728 - 149399:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (pk)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg3_104: pk
  PKS_AT (541..840): pk
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 79.2%
    Methylmalonyl-CoA: 66.7%
    Methoxymalonyl-CoA: 62.5%
  minowa: Methylmalonyl-CoA
  Prediction, score:
    Methylmalonyl-CoA: 105.0
    Methoxymalonyl-CoA: 93.8
    Malonyl-CoA: 81.4
    Ethylmalonyl-CoA: 59.0
    Isobutyryl-CoA: 53.8
    2-Methylbutyryl-CoA: 49.4
    trans-1,2-CPDA: 48.0
    Propionyl-CoA: 43.3
    inactive: 31.2
    fatty_acid: 30.5
    Benzoyl-CoA: 26.3
    CHC-CoA: 25.6
    3-Methylbutyryl-CoA: 17.3
    Acetyl-CoA: 6.5

c00003_NZ_CABK.. - Region 3 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 615,549 - 637,686 nt. (total: 22,138 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001588.1 |  | 0.16 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.16 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001925.1 |  | 0.14 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0001057.1 |  | 0.12 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001838.1 |  | 0.11 | NRP | WLIP | Pseudomonas putida
BGC0001865.1 |  | 0.10 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001739.1 |  | 0.10 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001100.1 |  | 0.09 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001120.1 |  | 0.09 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001338.1 |  | 0.09 | Polyketide | citrinin | Monascus ruber

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001588.1 |  | 0.47 | Saccharide | exopolysaccharides | Burkholderia pseudomallei 1026b
BGC0001589.1 |  | 0.47 | Saccharide | exopolysaccharides | Burkholderia cenocepacia J2315
BGC0001925.1 |  | 0.43 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0001057.1 |  | 0.39 | NRP, Polyketide | zearalenone | Fusarium graminearum
BGC0001838.1 |  | 0.38 | NRP | WLIP | Pseudomonas putida
BGC0001865.1 |  | 0.35 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001739.1 |  | 0.35 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001100.1 |  | 0.34 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001120.1 |  | 0.33 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001338.1 |  | 0.33 | Polyketide | citrinin | Monascus ruber

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names