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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AP019734.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | arylpolyene | 1,367,653 | 1,415,510 | flexirubin | Polyketide | 19%
Region 2 | RRE-containing | 2,731,806 | 2,752,072 |

NZ_AP019734.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 1,367,653 - 1,415,510 nt. (total: 47,858 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.28 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001538.1 |  | 0.26 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001723.1 |  | 0.24 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001197.1 |  | 0.22 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0001897.1 |  | 0.21 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000838.1 |  | 0.21 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001485.1 |  | 0.20 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.20 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0000275.1 |  | 0.20 | Polyketide | tetracenomycin C | Streptomyces glaucescens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000839.1 |  | 0.61 | Other | flexirubin | Chitinophaga pinensis DSM 2588
BGC0001538.1 |  | 0.59 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0001197.1 |  | 0.55 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0001897.1 |  | 0.54 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000838.1 |  | 0.54 | Polyketide | flexirubin | Flavobacterium johnsoniae UW101
BGC0000248.1 |  | 0.53 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0001485.1 |  | 0.53 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.53 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0000275.1 |  | 0.52 | Polyketide | tetracenomycin C | Streptomyces glaucescens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP019734.1 - Region 2 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,731,806 - 2,752,072 nt. (total: 20,267 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001804.1 |  | 0.06 | Polyketide | tiancimycin | Streptomyces sp. CB03234
BGC0001378.1 |  | 0.06 | Polyketide | tiancimycin | Streptomyces sp. CB03234
BGC0000236.1 |  | 0.05 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0001569.1 |  | 0.05 | NRP | dechlorocuracomycin | Streptomyces noursei ATCC 11455
BGC0001614.1 |  | 0.04 | NRP | hassallidin E | Planktothrix serta PCC 8927
BGC0001728.1 |  | 0.04 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0001666.1 |  | 0.04 | Polyketide | microansamycin | Micromonospora sp. HK160111
BGC0001303.1 |  | 0.03 | Polyketide | lobosamide A, lobosamide B, lobosamide C | Micromonospora sp. RL09-050-HVF-A
BGC0001503.1 |  | 0.03 | Polyketide | amycolamycin A, amycolamycin B | Amycolatopsis sp.

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001804.1 |  | 0.26 | Polyketide | tiancimycin | Streptomyces sp. CB03234
BGC0001378.1 |  | 0.26 | Polyketide | tiancimycin | Streptomyces sp. CB03234
BGC0000236.1 |  | 0.24 | Polyketide | kinamycin | Streptomyces murayamaensis
BGC0001569.1 |  | 0.22 | NRP | dechlorocuracomycin | Streptomyces noursei ATCC 11455
BGC0001614.1 |  | 0.20 | NRP | hassallidin E | Planktothrix serta PCC 8927
BGC0001728.1 |  | 0.20 | NRP, Polyketide | paenilipoheptin | Paenibacillus polymyxa E681
BGC0001666.1 |  | 0.18 | Polyketide | microansamycin | Micromonospora sp. HK160111
BGC0001303.1 |  | 0.16 | Polyketide | lobosamide A, lobosamide B, lobosamide C | Micromonospora sp. RL09-050-HVF-A
BGC0001503.1 |  | 0.15 | Polyketide | amycolamycin A, amycolamycin B | Amycolatopsis sp.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names