Select genomic region:
Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8
1.9
4.1
5.1

### Identified secondary metabolite regions using strictness 'relaxed'

NC_010505.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | redox-cofactor | 542,815 | 565,042 |
Region 1.2 | T1PKS | 981,360 | 1,028,739 |
Region 1.3 | NRPS-like | 1,390,090 | 1,432,430 | taiwachelin | NRP | 11%
Region 1.4 | terpene | 2,400,470 | 2,420,370 |
Region 1.5 | terpene | 2,980,762 | 3,000,952 | carotenoid | Terpene | 100%
Region 1.6 | T3PKS | 4,993,618 | 5,034,691 |
Region 1.7 | terpene | 5,716,755 | 5,741,840 |
Region 1.8 | NAPAA | 5,828,257 | 5,862,327 |
Region 1.9 | hserlactone | 6,062,829 | 6,077,833 |

NC_010514.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 4.1 | hserlactone | 17,059 | 37,712 |

NC_010517.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | hserlactone | 1,044 | 21,697 | lipopolysaccharide | Saccharide | 16%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | redox-cofactor | 542,815 | 565,042 |
Region 1.2 | T1PKS | 981,360 | 1,028,739 |
Region 1.3 | NRPS-like | 1,390,090 | 1,432,430 | taiwachelin | NRP | 11%
Region 1.4 | terpene | 2,400,470 | 2,420,370 |
Region 1.5 | terpene | 2,980,762 | 3,000,952 | carotenoid | Terpene | 100%
Region 1.6 | T3PKS | 4,993,618 | 5,034,691 |
Region 1.7 | terpene | 5,716,755 | 5,741,840 |
Region 1.8 | NAPAA | 5,828,257 | 5,862,327 |
Region 1.9 | hserlactone | 6,062,829 | 6,077,833 |
Region 4.1 | hserlactone | 17,059 | 37,712 |
Region 5.1 | hserlactone | 1,044 | 21,697 | lipopolysaccharide | Saccharide | 16%

No secondary metabolite regions were found in these records:
  NC_010510.1
  NC_010509.1
  NC_010518.1
  NC_010502.1
  NC_010504.1
  NC_010507.1

Compact view
NC_010505.1 - Region 1 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 542,815 - 565,042 nt. (total: 22,228 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000536.1 |  | 0.09 | RiPP | nisin Q | Lactococcus lactis
BGC0001727.1 |  | 0.09 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000527.1 |  | 0.09 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000535.1 |  | 0.09 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0001100.1 |  | 0.08 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0000545.1 |  | 0.07 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0001233.1 |  | 0.06 | NRP | feglymycin | Streptomyces sp. DSM 11171
BGC0001961.1 |  | 0.05 | NRP | ashimides | Streptomyces sp.
BGC0000080.1 |  | 0.05 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000997.1 |  | 0.05 | NRP, Polyketide | glidobactin | [Polyangium] brachysporum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000536.1 |  | 0.33 | RiPP | nisin Q | Lactococcus lactis
BGC0001727.1 |  | 0.33 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000527.1 |  | 0.33 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000535.1 |  | 0.33 | RiPP | nisin A | Lactococcus lactis subsp. lactis
BGC0001100.1 |  | 0.31 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0000545.1 |  | 0.28 | RiPP | ruminococcin A | [Ruminococcus] gnavus E1
BGC0001233.1 |  | 0.25 | NRP | feglymycin | Streptomyces sp. DSM 11171
BGC0001961.1 |  | 0.24 | NRP | ashimides | Streptomyces sp.
BGC0000080.1 |  | 0.24 | Polyketide | jerangolid A, jerangolid D | Sorangium cellulosum
BGC0000997.1 |  | 0.24 | NRP, Polyketide | glidobactin | [Polyangium] brachysporum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010505.1 - Region 2 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 981,360 - 1,028,739 nt. (total: 47,380 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.31 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001124.1 |  | 0.29 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001749.1 |  | 0.28 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0000046.1 |  | 0.28 | Polyketide | depudecin | Alternaria brassicicola
BGC0001697.1 |  | 0.27 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001067.1 |  | 0.26 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001340.1 |  | 0.25 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0001504.1 |  | 0.25 | Polyketide | amycomicin | Amycolatopsis sp. AA4
BGC0001913.1 |  | 0.25 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0000056.1 |  | 0.24 | Polyketide | esperamicin | Actinomadura verrucosospora

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001909.1 |  | 0.65 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001124.1 |  | 0.62 | Polyketide | pyranonigrin E | Aspergillus niger ATCC 1015
BGC0001749.1 |  | 0.62 | Polyketide | epipyriculol | Pyricularia oryzae 70-15
BGC0000046.1 |  | 0.61 | Polyketide | depudecin | Alternaria brassicicola
BGC0001697.1 |  | 0.60 | Polyketide | neurosporin A | Neurospora crassa OR74A
BGC0001067.1 |  | 0.60 | Polyketide, Terpene | fumagillin, β-trans-bergamotene, fumagillol | Aspergillus fumigatus Af293
BGC0001340.1 |  | 0.59 | Polyketide | byssochlamic acid | Byssochlamys fulva
BGC0001504.1 |  | 0.59 | Polyketide | amycomicin | Amycolatopsis sp. AA4
BGC0001913.1 |  | 0.58 | Polyketide | phomoidride | fungal sp. ATCC 74256
BGC0000056.1 |  | 0.57 | Polyketide | esperamicin | Actinomadura verrucosospora

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 981359 - 1028739:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (redmal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_954: mal
  PKS_AT (510..805): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 75.0%
    Propionyl-CoA: 66.7%
    Methylmalonyl-CoA: 62.5%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 88.9
    Methylmalonyl-CoA: 81.9
    Methoxymalonyl-CoA: 71.5
    Isobutyryl-CoA: 55.4
    Ethylmalonyl-CoA: 43.0
    Benzoyl-CoA: 41.3
    inactive: 33.5
    Propionyl-CoA: 26.8
    fatty_acid: 25.3
    trans-1,2-CPDA: 23.5
    3-Methylbutyryl-CoA: 16.3
    CHC-CoA: 13.7
    Acetyl-CoA: 12.3
    2-Methylbutyryl-CoA: 12.1

NC_010505.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,390,090 - 1,432,430 nt. (total: 42,341 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000340.1 |  | 0.28 | NRP | echoside A, echoside B, echoside C, echoside D, echoside E | Streptomyces sp. LZ35
BGC0000343.1 |  | 0.25 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000221.1 |  | 0.23 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000957.1 |  | 0.23 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0001591.1 |  | 0.22 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.22 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000375.1 |  | 0.22 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000427.1 |  | 0.21 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001399.1 |  | 0.21 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001343.1 |  | 0.21 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000340.1 |  | 0.61 | NRP | echoside A, echoside B, echoside C, echoside D, echoside E | Streptomyces sp. LZ35
BGC0000343.1 |  | 0.58 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000221.1 |  | 0.57 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000957.1 |  | 0.56 | NRP, Polyketide | mycotrienin I | Streptomyces sp. XZQH13
BGC0001591.1 |  | 0.56 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.56 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000375.1 |  | 0.55 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000427.1 |  | 0.54 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001399.1 |  | 0.54 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001343.1 |  | 0.53 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1390089 - 1432430:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1347: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (118..524): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgegsGGIsK
    Nearest Stachelhaus code:
      orn
    Stachelhaus code match:
      50% (weak)

NC_010505.1 - Region 4 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,400,470 - 2,420,370 nt. (total: 19,901 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.19 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0000703.1 |  | 0.15 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000706.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000894.1 |  | 0.14 | Other | citrinin | Monascus aurantiacus
BGC0001633.1 |  | 0.12 | Other | ketomemicin B3, ketomemicin B4 | Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001338.1 |  | 0.07 | Polyketide | citrinin | Monascus ruber
BGC0000700.1 |  | 0.05 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000038.1 |  | 0.05 | Polyketide | coelimycin P1 | Streptomyces coelicolor A3(2)
BGC0000119.1 |  | 0.05 | Polyketide, Saccharide | 7-deoxypactamycin | Streptomyces pactum
BGC0000001.1 |  | 0.05 | Polyketide | abyssomicin C, atrop-abyssomicin C | Verrucosispora maris AB-18-032

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.51 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0000703.1 |  | 0.45 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000706.1 |  | 0.44 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000894.1 |  | 0.44 | Other | citrinin | Monascus aurantiacus
BGC0001633.1 |  | 0.40 | Other | ketomemicin B3, ketomemicin B4 | Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001338.1 |  | 0.29 | Polyketide | citrinin | Monascus ruber
BGC0000700.1 |  | 0.22 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000038.1 |  | 0.21 | Polyketide | coelimycin P1 | Streptomyces coelicolor A3(2)
BGC0000119.1 |  | 0.21 | Polyketide, Saccharide | 7-deoxypactamycin | Streptomyces pactum
BGC0000001.1 |  | 0.21 | Polyketide | abyssomicin C, atrop-abyssomicin C | Verrucosispora maris AB-18-032

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010505.1 - Region 5 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,980,762 - 3,000,952 nt. (total: 20,191 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.51 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.35 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.25 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000646.1 |  | 0.24 | Terpene | β-carotein | uncultured bacterium
BGC0000780.1 |  | 0.24 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0000787.1 |  | 0.23 | Saccharide | O-antigen | Escherichia coli
BGC0000799.1 |  | 0.23 | Saccharide | colanic acid | Escherichia coli
BGC0000788.1 |  | 0.23 | Saccharide | O-antigen | Salmonella enterica subsp. salamae serovar Greenside
BGC0000733.1 |  | 0.23 | Saccharide | capsular polysaccharide | Klebsiella pneumoniae
BGC0000732.1 |  | 0.22 | Saccharide | capsular polysaccharide | Raoultella planticola

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.79 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.68 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.59 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000646.1 |  | 0.57 | Terpene | β-carotein | uncultured bacterium
BGC0000780.1 |  | 0.57 | Saccharide | O&K-antigen | Vibrio parahaemolyticus
BGC0000787.1 |  | 0.56 | Saccharide | O-antigen | Escherichia coli
BGC0000799.1 |  | 0.56 | Saccharide | colanic acid | Escherichia coli
BGC0000788.1 |  | 0.56 | Saccharide | O-antigen | Salmonella enterica subsp. salamae serovar Greenside
BGC0000733.1 |  | 0.56 | Saccharide | capsular polysaccharide | Klebsiella pneumoniae
BGC0000732.1 |  | 0.55 | Saccharide | capsular polysaccharide | Raoultella planticola

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010505.1 - Region 6 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,993,618 - 5,034,691 nt. (total: 41,074 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001962.1 |  | 0.35 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.35 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0000282.1 |  | 0.33 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.1 |  | 0.29 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001895.1 |  | 0.24 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0002000.1 |  | 0.21 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001964.1 |  | 0.21 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium
BGC0001897.1 |  | 0.20 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000842.1 |  | 0.20 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0002016.1 |  | 0.19 | Polyketide | lugdunomycin | Streptomyces sp. QL37

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001962.1 |  | 0.68 | Polyketide | hierridin B, hierridin C | Cyanobium sp. LEGE 06113
BGC0001938.1 |  | 0.68 | Polyketide | entotheonella | Candidatus Entotheonella serta
BGC0000282.1 |  | 0.66 | Polyketide | alkylresorcinol | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001831.1 |  | 0.63 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Myxococcus xanthus DK 1622
BGC0001895.1 |  | 0.57 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0002000.1 |  | 0.54 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0001964.1 |  | 0.54 | Polyketide | alkylpyrone-407, alkylpyrone-393 | Cystobacterineae bacterium
BGC0001897.1 |  | 0.52 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000842.1 |  | 0.52 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0002016.1 |  | 0.51 | Polyketide | lugdunomycin | Streptomyces sp. QL37

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010505.1 - Region 7 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,716,755 - 5,741,840 nt. (total: 25,086 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.25 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.23 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000386.1 |  | 0.23 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0000634.1 |  | 0.20 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.20 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000630.1 |  | 0.20 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000640.1 |  | 0.19 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000633.1 |  | 0.18 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.17 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.1 |  | 0.16 | Terpene | isorenieratene | Streptomyces collinus Tu 365

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.58 | Terpene | carotenoid | Myxococcus xanthus
BGC0000656.1 |  | 0.56 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000386.1 |  | 0.56 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0000634.1 |  | 0.53 | Terpene | carotenoid | Brevundimonas sp. SD212
BGC0000643.1 |  | 0.53 | Terpene | carotenoid | Brevundimonas vesicularis
BGC0000630.1 |  | 0.52 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000640.1 |  | 0.51 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000633.1 |  | 0.50 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.49 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.1 |  | 0.47 | Terpene | isorenieratene | Streptomyces collinus Tu 365

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010505.1 - Region 8 - NAPAA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,828,257 - 5,862,327 nt. (total: 34,071 nt) Show pHMM detection rules used
NAPAA: (AMP-binding and PP-binding and TIGR02353)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAPAA | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000375.1 |  | 0.22 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000427.1 |  | 0.21 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001399.1 |  | 0.21 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001897.1 |  | 0.20 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000343.1 |  | 0.19 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001458.1 |  | 0.19 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440
BGC0001844.1 |  | 0.19 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.19 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.19 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001778.1 |  | 0.19 | Other | showdomycin | Streptomyces showdoensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000375.1 |  | 0.55 | NRP | indigoidine | Streptomyces chromofuscus
BGC0000427.1 |  | 0.54 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001399.1 |  | 0.54 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001897.1 |  | 0.52 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000343.1 |  | 0.51 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001458.1 |  | 0.51 | Other (Aminocoumarin) | salinipostin G | Salinispora tropica CNB-440
BGC0001844.1 |  | 0.50 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.50 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.50 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001778.1 |  | 0.50 | Other | showdomycin | Streptomyces showdoensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 8, location 5828256 - 5862327:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_5499: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (44..445): X
  NRPSPredictor2: hydrophobic-aliphatic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLedLgTVvK
    Nearest Stachelhaus code:
      ala
    Stachelhaus code match:
      60% (weak)

NC_010505.1 - Region 9 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 6,062,829 - 6,077,833 nt. (total: 15,005 nt) Show pHMM detection rules used
Region on contig edge.
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000815.1 |  | 0.17 | Alkaloid | loline | Epichloe uncinata
BGC0000783.1 |  | 0.16 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000504.1 |  | 0.15 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000886.1 |  | 0.15 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000734.1 |  | 0.14 | Saccharide | capsular polysaccharide | Pasteurella multocida
BGC0000736.1 |  | 0.14 | Saccharide | capsular polysaccharide | Mannheimia haemolytica
BGC0000703.1 |  | 0.13 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001891.1 |  | 0.13 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0000538.1 |  | 0.12 | RiPP | nisin Z | Lactococcus lactis
BGC0000497.1 |  | 0.11 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000815.1 |  | 0.48 | Alkaloid | loline | Epichloe uncinata
BGC0000783.1 |  | 0.46 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000504.1 |  | 0.45 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000886.1 |  | 0.45 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0000734.1 |  | 0.44 | Saccharide | capsular polysaccharide | Pasteurella multocida
BGC0000736.1 |  | 0.43 | Saccharide | capsular polysaccharide | Mannheimia haemolytica
BGC0000703.1 |  | 0.42 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001891.1 |  | 0.42 | Other | closthioamide | Ruminiclostridium cellulolyticum H10
BGC0000538.1 |  | 0.40 | RiPP | nisin Z | Lactococcus lactis
BGC0000497.1 |  | 0.38 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_010514.1 - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 17,059 - 37,712 nt. (total: 20,654 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000509.1 |  | 0.06 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000961.1 |  | 0.04 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0000700.1 |  | 0.04 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000209.1 |  | 0.03 | Polyketide | chlortetracycline | Kitasatospora aureofaciens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000509.1 |  | 0.25 | RiPP | epilancin 15x | Staphylococcus epidermidis
BGC0000961.1 |  | 0.20 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0000700.1 |  | 0.19 | Saccharide | istamycin | Streptomyces tenjimariensis
BGC0000209.1 |  | 0.16 | Polyketide | chlortetracycline | Kitasatospora aureofaciens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NC_010517.1 - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,044 - 21,697 nt. (total: 20,654 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.18 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0001605.1 |  | 0.17 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001140.1 |  | 0.16 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001928.1 |  | 0.16 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001156.1 |  | 0.16 | Terpene | platencin | Streptomyces platensis
BGC0000772.1 |  | 0.15 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0001138.1 |  | 0.15 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0000866.1 |  | 0.15 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000867.1 |  | 0.14 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000204.1 |  | 0.07 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000386.1 |  | 0.49 | NRP | malleobactin A, malleobactin B, malleobactin C, malleobactin D | Burkholderia thailandensis E264
BGC0001605.1 |  | 0.48 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001140.1 |  | 0.47 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0001928.1 |  | 0.46 | Other | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0001156.1 |  | 0.46 | Terpene | platencin | Streptomyces platensis
BGC0000772.1 |  | 0.44 | Saccharide | lipopolysaccharide | Brucella melitensis
BGC0001138.1 |  | 0.44 | Other (Nucleoside) | a201a | Marinactinospora thermotolerans
BGC0000866.1 |  | 0.44 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000867.1 |  | 0.44 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000204.1 |  | 0.27 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200

Similar known gene clusters
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Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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