LOCUS       NZ_AP022642.1          21431 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP022642.1 Pseudomonas otitidis strain MrB4 chromosome, complete
            genome.
ACCESSION   NZ_AP022642
VERSION     NZ_AP022642.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:41:52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2741159
            Orig. end    :: 2762590
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21431
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2751159:2752590](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11431
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21431
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21431
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="4"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(871..1320)
                     /locus_tag="ctg1_2484"
                     /transl_table=11
                     /translation="MTNHEALSLAEACGSALFERDTASQAMGMRLLSVAPGQAQMGMTV
                     RADMVQGHGTCHGGYLFALADSAFAFACNSYNEATVAIGCSIDYVAPARLGDTLTAQAS
                     EQSRSGRTGNYDVRIENQNGQLIALFHGKSYKVRGTVLAQETPDE"
     aSDomain        complement(910..1248)
                     /aSDomain="TIGR02286"
                     /aSTool="tigrfam"
                     /description="PaaD: phenylacetic acid degradation protein
                     PaaD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2484_0020"
                     /evalue="2.20E-50"
                     /identifier="TIGR02286"
                     /label="ctg1_2484"
                     /locus_tag="ctg1_2484"
                     /protein_end="137"
                     /protein_start="24"
                     /score="167.6"
                     /tool="antismash"
                     /translation="QAMGMRLLSVAPGQAQMGMTVRADMVQGHGTCHGGYLFALADSAF
                     AFACNSYNEATVAIGCSIDYVAPARLGDTLTAQASEQSRSGRTGNYDVRIENQNGQLIA
                     LFHGKSYKV"
     aSDomain        complement(919..1251)
                     /aSDomain="TIGR00369"
                     /aSTool="tigrfam"
                     /description="unchar_dom_1: uncharacterized domain 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2484_0021"
                     /evalue="7.30E-24"
                     /identifier="TIGR00369"
                     /label="ctg1_2484"
                     /locus_tag="ctg1_2484"
                     /protein_end="134"
                     /protein_start="23"
                     /score="82.1"
                     /tool="antismash"
                     /translation="SQAMGMRLLSVAPGQAQMGMTVRADMVQGHGTCHGGYLFALADSA
                     FAFACNSYNEATVAIGCSIDYVAPARLGDTLTAQASEQSRSGRTGNYDVRIENQNGQLI
                     ALFHGKS"
     PFAM_domain     complement(940..1164)
                     /aSDomain="4HBT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03061.24"
                     /description="Thioesterase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2484_0062"
                     /evalue="8.00E-16"
                     /label="ctg1_2484"
                     /locus_tag="ctg1_2484"
                     /protein_end="127"
                     /protein_start="52"
                     /score="58.2"
                     /tool="antismash"
                     /translation="HGTCHGGYLFALADSAFAFACNSYNEATVAIGCSIDYVAPARLGD
                     TLTAQASEQSRSGRTGNYDVRIENQNGQLI"
     CDS             complement(1307..2830)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095:3-hydroxybutyryl-CoA dehydrogenase (Score: 52.6;
                     E-value: 6.7e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2485"
                     /transl_table=11
                     /translation="MPALPQTSLVAVIGAGAMGAGIAQVAAQAGHPVRLYDNRPGAAAQ
                     AVDGIDRQLGRLVEKGKLDAAERQAIVARLQPAETLEALADARLVIEAIVENLEIKRAL
                     LQQLEALCSPTCILASNTSSLSITALAAGLAHPGRVIGLHFFNPAPLMALVEVVSGLAS
                     DPALADALYATARAWGKQPVHTRSTPGFIVNRVARPFYAESLRLLQEGAADCATLDALM
                     REAGGFRMGAFELTDLIGHDVNYAVTCSVFEAYYGDFRFQPSLIQKELVDAGRLGRKSG
                     RGFYDYAEGAQRPTPAALSSEQTVDGCVVEGHLGVAEPLAARLQAAGLAVTRRDGTGLL
                     RVGDAVLALSDGRLASQRAREDGLANLVLLDLALDYAEASRLGITWAASTSALARDQAV
                     ALLQRAGITATPLADIPGLAVLRTVAMLANEGADAVLQGVGSAADIDLAMRAGVNYPKG
                     PLAWADAIGLAALLRTLDNLQVAYGEARYRPSLLLRRHVAEGRTFHDQP"
     aSDomain        complement(1316..2821)
                     /aSDomain="TIGR02279"
                     /aSTool="tigrfam"
                     /description="PaaC-3OHAcCoADH: 3-hydroxyacyl-CoA
                     dehydrogenase PaaC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2485_0022"
                     /evalue="6.00E-248"
                     /identifier="TIGR02279"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="505"
                     /protein_start="3"
                     /score="821.6"
                     /tool="antismash"
                     /translation="LPQTSLVAVIGAGAMGAGIAQVAAQAGHPVRLYDNRPGAAAQAVD
                     GIDRQLGRLVEKGKLDAAERQAIVARLQPAETLEALADARLVIEAIVENLEIKRALLQQ
                     LEALCSPTCILASNTSSLSITALAAGLAHPGRVIGLHFFNPAPLMALVEVVSGLASDPA
                     LADALYATARAWGKQPVHTRSTPGFIVNRVARPFYAESLRLLQEGAADCATLDALMREA
                     GGFRMGAFELTDLIGHDVNYAVTCSVFEAYYGDFRFQPSLIQKELVDAGRLGRKSGRGF
                     YDYAEGAQRPTPAALSSEQTVDGCVVEGHLGVAEPLAARLQAAGLAVTRRDGTGLLRVG
                     DAVLALSDGRLASQRAREDGLANLVLLDLALDYAEASRLGITWAASTSALARDQAVALL
                     QRAGITATPLADIPGLAVLRTVAMLANEGADAVLQGVGSAADIDLAMRAGVNYPKGPLA
                     WADAIGLAALLRTLDNLQVAYGEARYRPSLLLRRHVAEGRTFHD"
     PFAM_domain     complement(1328..1576)
                     /aSDomain="3HCDH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00725.24"
                     /description="3-hydroxyacyl-CoA dehydrogenase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2485_0066"
                     /evalue="3.60E-14"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="501"
                     /protein_start="418"
                     /score="53.1"
                     /tool="antismash"
                     /translation="AVLRTVAMLANEGADAVLQGVGSAADIDLAMRAGVNYPKGPLAWA
                     DAIGLAALLRTLDNLQVAYGEARYRPSLLLRRHVAEGR"
     PFAM_domain     complement(1583..1792)
                     /aSDomain="3HCDH_RFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18321.3"
                     /description="3-hydroxybutyryl-CoA dehydrogenase reduced
                     Rossmann-fold domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2485_0065"
                     /evalue="7.00E-19"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="416"
                     /protein_start="346"
                     /score="68.1"
                     /tool="antismash"
                     /translation="LALSDGRLASQRAREDGLANLVLLDLALDYAEASRLGITWAASTS
                     ALARDQAVALLQRAGITATPLADIP"
     PFAM_domain     complement(1970..2263)
                     /aSDomain="3HCDH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00725.24"
                     /description="3-hydroxyacyl-CoA dehydrogenase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2485_0064"
                     /evalue="2.00E-30"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="287"
                     /protein_start="189"
                     /score="105.2"
                     /tool="antismash"
                     /translation="GFIVNRVARPFYAESLRLLQEGAADCATLDALMREAGGFRMGAFE
                     LTDLIGHDVNYAVTCSVFEAYYGDFRFQPSLIQKELVDAGRLGRKSGRGFYDY"
     PFAM_domain     complement(2273..2803)
                     /aSDomain="3HCDH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02737.20"
                     /description="3-hydroxyacyl-CoA dehydrogenase, NAD binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2485_0063"
                     /evalue="8.00E-62"
                     /label="ctg1_2485"
                     /locus_tag="ctg1_2485"
                     /protein_end="186"
                     /protein_start="9"
                     /score="208.4"
                     /tool="antismash"
                     /translation="VAVIGAGAMGAGIAQVAAQAGHPVRLYDNRPGAAAQAVDGIDRQL
                     GRLVEKGKLDAAERQAIVARLQPAETLEALADARLVIEAIVENLEIKRALLQQLEALCS
                     PTCILASNTSSLSITALAAGLAHPGRVIGLHFFNPAPLMALVEVVSGLASDPALADALY
                     ATARAWGKQPVHTR"
     CDS             complement(2835..3626)
                     /NRPS_PKS="Domain: ECH (8-254). E-value: 6.1e-67. Score:
                     217.3. Matches aSDomain: nrpspksdomains_ctg1_2486_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 243.1; E-value:
                     4.3e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2486"
                     /transl_table=11
                     /translation="MTFEHILFSIEAGVATLSLNRPEQLNSFNAQMHGEVREALKQVRQ
                     DPAVRVLLLTGEGRGFCAGQDLADRNVAPGSEAPDLGTSIEQFYNPLIRTLRDLPMPVV
                     CAVNGVAAGAGANIPLACDLVLAARSASFIQAFCKIGLIPDSGGTWTLPRLVGMARAKA
                     LALLGERLSAEQAEQWGLIHRVVDDAALRDEALKLARHLATQPTYGLALIKRSLNASLD
                     NSFDQQLELERDLQRLAGRSEDYREGVSAFMAKRTPVFKGR"
     aSDomain        complement(2838..3611)
                     /aSDomain="TIGR02280"
                     /aSTool="tigrfam"
                     /description="PaaB1: phenylacetate degradation probable
                     enoyl-CoA hydratase PaaB"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2486_0023"
                     /evalue="2.90E-129"
                     /identifier="TIGR02280"
                     /label="ctg1_2486"
                     /locus_tag="ctg1_2486"
                     /protein_end="263"
                     /protein_start="5"
                     /score="428.0"
                     /tool="antismash"
                     /translation="ILFSIEAGVATLSLNRPEQLNSFNAQMHGEVREALKQVRQDPAVR
                     VLLLTGEGRGFCAGQDLADRNVAPGSEAPDLGTSIEQFYNPLIRTLRDLPMPVVCAVNG
                     VAAGAGANIPLACDLVLAARSASFIQAFCKIGLIPDSGGTWTLPRLVGMARAKALALLG
                     ERLSAEQAEQWGLIHRVVDDAALRDEALKLARHLATQPTYGLALIKRSLNASLDNSFDQ
                     QLELERDLQRLAGRSEDYREGVSAFMAKRTPVFKGR"
     PFAM_domain     complement(2841..3599)
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2486_0067"
                     /evalue="4.10E-67"
                     /label="ctg1_2486"
                     /locus_tag="ctg1_2486"
                     /protein_end="262"
                     /protein_start="9"
                     /score="226.2"
                     /tool="antismash"
                     /translation="IEAGVATLSLNRPEQLNSFNAQMHGEVREALKQVRQDPAVRVLLL
                     TGEGRGFCAGQDLADRNVAPGSEAPDLGTSIEQFYNPLIRTLRDLPMPVVCAVNGVAAG
                     AGANIPLACDLVLAARSASFIQAFCKIGLIPDSGGTWTLPRLVGMARAKALALLGERLS
                     AEQAEQWGLIHRVVDDAALRDEALKLARHLATQPTYGLALIKRSLNASLDNSFDQQLEL
                     ERDLQRLAGRSEDYREGVSAFMAKRTPVFKG"
     aSDomain        complement(2865..3602)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2486_ECH.1"
                     /evalue="6.10E-67"
                     /label="ctg1_2486_ECH.1"
                     /locus_tag="ctg1_2486"
                     /protein_end="254"
                     /protein_start="8"
                     /score="217.3"
                     /tool="antismash"
                     /translation="SIEAGVATLSLNRPEQLNSFNAQMHGEVREALKQVRQDPAVRVLL
                     LTGEGRGFCAGQDLADRNVAPGSEAPDLGTSIEQFYNPLIRTLRDLPMPVVCAVNGVAA
                     GAGANIPLACDLVLAARSASFIQAFCKIGLIPDSGGTWTLPRLVGMARAKALALLGERL
                     SAEQAEQWGLIHRVVDDAALRDEALKLARHLATQPTYGLALIKRSLNASLDNSFDQQLE
                     LERDLQRLAGRSEDYREGVSAFMA"
     CDS             complement(3668..4441)
                     /NRPS_PKS="Domain: ECH (12-249). E-value: 1.3e-72. Score:
                     235.8. Matches aSDomain: nrpspksdomains_ctg1_2487_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 248; E-value:
                     1.4e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2487"
                     /transl_table=11
                     /translation="MPRTLAVLPPELGVRLITLQRPEALNALNTELLGELAAELDLAEQ
                     DADTRAVVITGSRRAFAAGADIQEMAERDLVGILNDPRQAHWQRIARFGKPLVAAVNGF
                     CLGGGCELAMHADILIAGEDARFGQPEINLGIMPGAGGTQRLLRAVGKSLAMQMVLTGE
                     AIDARHALRAGLVSEVTQPEFTVERALAIARLIAQKAPLAVRLAKEAVLKAEDTDLASG
                     LRFERHAFTLLAGTRDRDEGIRAFQEKRRPDFTGQ"
     PFAM_domain     complement(3671..4405)
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2487_0068"
                     /evalue="1.70E-72"
                     /label="ctg1_2487"
                     /locus_tag="ctg1_2487"
                     /protein_end="257"
                     /protein_start="12"
                     /score="243.9"
                     /tool="antismash"
                     /translation="GVRLITLQRPEALNALNTELLGELAAELDLAEQDADTRAVVITGS
                     RRAFAAGADIQEMAERDLVGILNDPRQAHWQRIARFGKPLVAAVNGFCLGGGCELAMHA
                     DILIAGEDARFGQPEINLGIMPGAGGTQRLLRAVGKSLAMQMVLTGEAIDARHALRAGL
                     VSEVTQPEFTVERALAIARLIAQKAPLAVRLAKEAVLKAEDTDLASGLRFERHAFTLLA
                     GTRDRDEGIRAFQEKRRPDFTGQ"
     aSDomain        complement(3695..4405)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2487_ECH.1"
                     /evalue="1.30E-72"
                     /label="ctg1_2487_ECH.1"
                     /locus_tag="ctg1_2487"
                     /protein_end="249"
                     /protein_start="12"
                     /score="235.8"
                     /tool="antismash"
                     /translation="GVRLITLQRPEALNALNTELLGELAAELDLAEQDADTRAVVITGS
                     RRAFAAGADIQEMAERDLVGILNDPRQAHWQRIARFGKPLVAAVNGFCLGGGCELAMHA
                     DILIAGEDARFGQPEINLGIMPGAGGTQRLLRAVGKSLAMQMVLTGEAIDARHALRAGL
                     VSEVTQPEFTVERALAIARLIAQKAPLAVRLAKEAVLKAEDTDLASGLRFERHAFTLLA
                     GTRDRDEGIRAFQEK"
     CDS             4778..5374
                     /locus_tag="ctg1_2488"
                     /transl_table=11
                     /translation="MACYSLDGLVPVVHPTAYVHPSAVLIGDVIIGPHCYVGPLASLRG
                     DFGRIVLEEGANIQDTCVMHGFPGSDTVVARNGHIGHGAVLHGCQIGEDALVGMNAVVM
                     DGARIGARSFVSATAFVKAGFTCDAQSLVMGSPAQVRRVLSDDEVAWKQAGTREYQRLA
                     QRCLAALEPCEPLAEVEPGRPRMSDPGLRPKGEAH"
     aSDomain        4784..5359
                     /aSDomain="TIGR02287"
                     /aSTool="tigrfam"
                     /description="PaaY: phenylacetic acid degradation protein
                     PaaY"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2488_0024"
                     /evalue="1.00E-105"
                     /identifier="TIGR02287"
                     /label="ctg1_2488"
                     /locus_tag="ctg1_2488"
                     /protein_end="194"
                     /protein_start="2"
                     /score="349.5"
                     /tool="antismash"
                     /translation="CYSLDGLVPVVHPTAYVHPSAVLIGDVIIGPHCYVGPLASLRGDF
                     GRIVLEEGANIQDTCVMHGFPGSDTVVARNGHIGHGAVLHGCQIGEDALVGMNAVVMDG
                     ARIGARSFVSATAFVKAGFTCDAQSLVMGSPAQVRRVLSDDEVAWKQAGTREYQRLAQR
                     CLAALEPCEPLAEVEPGRPRMSDPGLRPK"
     CDS             5463..6386
                     /locus_tag="ctg1_2489"
                     /transl_table=11
                     /translation="MTSLAPLDQLITRFQQQTPIRASSLIMTLYGDAIEPHGGTVWLGS
                     LIQMLEPIGINERLIRTSIFRLTKDGWLSAEKVGRRSYYSLTGTGRRRFEKAFKRVYSS
                     GIPAWDGSWHLVVLSQLPQEKRKQVREELEWQGFGAIAPTVLANPRCDRVDLTTTLQEL
                     DALEDSIVFETSAQDVLASKALRMQVRESWRLDELGEHYREFIQLFRPLWQALREQESL
                     DPEDCLLARTLLIHEYRRLLLRDPQLPDELLPSDWEGRSARQLCRNIYRLIYAKAEEWL
                     NANLETADGPLPDASEGFYRRFGGLR"
     PFAM_domain     5523..5729
                     /aSDomain="PaaX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07848.14"
                     /description="PaaX-like protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2489_0069"
                     /evalue="1.00E-30"
                     /label="ctg1_2489"
                     /locus_tag="ctg1_2489"
                     /protein_end="89"
                     /protein_start="20"
                     /score="105.8"
                     /tool="antismash"
                     /translation="RASSLIMTLYGDAIEPHGGTVWLGSLIQMLEPIGINERLIRTSIF
                     RLTKDGWLSAEKVGRRSYYSLTGT"
     aSDomain        5532..6374
                     /aSDomain="TIGR02277"
                     /aSTool="tigrfam"
                     /description="PaaX_trns_reg: phenylacetic acid degradation
                     operon negative regulatory protein PaaX"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2489_0025"
                     /evalue="6.90E-101"
                     /identifier="TIGR02277"
                     /label="ctg1_2489"
                     /locus_tag="ctg1_2489"
                     /protein_end="304"
                     /protein_start="23"
                     /score="335.4"
                     /tool="antismash"
                     /translation="SLIMTLYGDAIEPHGGTVWLGSLIQMLEPIGINERLIRTSIFRLT
                     KDGWLSAEKVGRRSYYSLTGTGRRRFEKAFKRVYSSGIPAWDGSWHLVVLSQLPQEKRK
                     QVREELEWQGFGAIAPTVLANPRCDRVDLTTTLQELDALEDSIVFETSAQDVLASKALR
                     MQVRESWRLDELGEHYREFIQLFRPLWQALREQESLDPEDCLLARTLLIHEYRRLLLRD
                     PQLPDELLPSDWEGRSARQLCRNIYRLIYAKAEEWLNANLETADGPLPDASEGFYRRFG
                     "
     PFAM_domain     6021..6308
                     /aSDomain="PaaX_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08223.13"
                     /description="PaaX-like protein C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2489_0070"
                     /evalue="2.60E-34"
                     /label="ctg1_2489"
                     /locus_tag="ctg1_2489"
                     /protein_end="282"
                     /protein_start="186"
                     /score="117.6"
                     /tool="antismash"
                     /translation="MQVRESWRLDELGEHYREFIQLFRPLWQALREQESLDPEDCLLAR
                     TLLIHEYRRLLLRDPQLPDELLPSDWEGRSARQLCRNIYRLIYAKAEEWLN"
     CDS             complement(6462..7955)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 514.5; E-value:
                     3.4e-156)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2490"
                     /transl_table=11
                     /translation="MSDQLPLLPATRAFLDRPLKMLIGDQWQDATSGATLDFRNPATGD
                     VIGRVPSADADDVDRAVRAARQAFDDSAWSRMRPRERQNLLWRLADLMQRDAQQLAELE
                     CLNNGKSAAVAQVMDVQLAIDFLRYMAGWATKIEGSSVDVSLPLMPDDQFHGFIRREAV
                     GVVGAIVAWNFPLLLACWKLGPALATGCTVVLKPADETPVTALKLAELVLEAGYPAGVF
                     NVVTGTGLNAGAALTRHPGVDKLTFTGSTEVGKQIGKAAMDNMTRVTLELGGKSPTLVL
                     ADANLQDAAAGAATAIFFNQGQVCCAGSRLYVQRKHFDNVVADIAGIANGMKLGNGLDP
                     SVQMGPLISARQQDRVTGYINLGRELGASVVCGGEGFGPGYFVKPTVIADVDQKHRLVQ
                     EEIFGPVLVAMPFDDLDEAVRLANDNPYGLGASIWSNDLGAVHRMIPRIKSGSVWVNCH
                     SALDPALPFGGYKMSGLGREMGAAAIEHYTELKSVLMRL"
     PFAM_domain     complement(6477..7877)
                     /aSDomain="Aldedh"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00171.24"
                     /description="Aldehyde dehydrogenase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2490_0071"
                     /evalue="6.50E-176"
                     /label="ctg1_2490"
                     /locus_tag="ctg1_2490"
                     /protein_end="493"
                     /protein_start="26"
                     /score="585.5"
                     /tool="antismash"
                     /translation="WQDATSGATLDFRNPATGDVIGRVPSADADDVDRAVRAARQAFDD
                     SAWSRMRPRERQNLLWRLADLMQRDAQQLAELECLNNGKSAAVAQVMDVQLAIDFLRYM
                     AGWATKIEGSSVDVSLPLMPDDQFHGFIRREAVGVVGAIVAWNFPLLLACWKLGPALAT
                     GCTVVLKPADETPVTALKLAELVLEAGYPAGVFNVVTGTGLNAGAALTRHPGVDKLTFT
                     GSTEVGKQIGKAAMDNMTRVTLELGGKSPTLVLADANLQDAAAGAATAIFFNQGQVCCA
                     GSRLYVQRKHFDNVVADIAGIANGMKLGNGLDPSVQMGPLISARQQDRVTGYINLGREL
                     GASVVCGGEGFGPGYFVKPTVIADVDQKHRLVQEEIFGPVLVAMPFDDLDEAVRLANDN
                     PYGLGASIWSNDLGAVHRMIPRIKSGSVWVNCHSALDPALPFGGYKMSGLGREMGAAAI
                     EHYTELKSV"
     CDS             8362..9927
                     /locus_tag="ctg1_2491"
                     /transl_table=11
                     /translation="LKTTRLRRQAGSLVLTLAALLCAQAHGAEEGPALLQSKCMGCHIP
                     EGNDTYSRISHQRKTPEGWLMSIARMQVMHGLKISDEDRRTLVKYLADKQGLAPSETDG
                     VRYAMERRLNTVEQFDDHLSQMCGRCHSGARVALQRRPAKEWEHLVNFHLGQWPSLEYQ
                     AQSRDRDWLDIALKQTVPDLAKRFPLDSQAWTDWQKARPKADVLPGQWSFSGHMLAKGD
                     VRGVMTVTADGADTFKVDVKGQYADGSPFTGSGSAILYNGYEWRGNVKVGDTTLRQVFA
                     ALDGQMTGRMFESEHDERGLDFSAAKQGQARLLAVQPAQVKAGSETELTLVGSGLSGAP
                     QLGAGLEVVKVLDSTPDHVRVKVKAAADAAPGLREVSIGALKGVTLAVYKDIAEVKVVP
                     AFSIARIGENGGSTPKVQGRFEAEAWGTDAAGKAYRIGYLPAKWSVEPFDERAKEDEDV
                     KFAGVMQKDGVFVPGGAGPNPERKMMTNNAGNLKVIAELEEGGQKGEGHLIVTVQRWNN
                     PPLP"
     aSDomain        8434..9921
                     /aSDomain="TIGR03908"
                     /aSTool="tigrfam"
                     /description="QH_alpha: quinohemoprotein amine
                     dehydrogenase, alpha subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2491_0026"
                     /evalue="3.80E-210"
                     /identifier="TIGR03908"
                     /label="ctg1_2491"
                     /locus_tag="ctg1_2491"
                     /protein_end="520"
                     /protein_start="24"
                     /score="696.7"
                     /tool="antismash"
                     /translation="AHGAEEGPALLQSKCMGCHIPEGNDTYSRISHQRKTPEGWLMSIA
                     RMQVMHGLKISDEDRRTLVKYLADKQGLAPSETDGVRYAMERRLNTVEQFDDHLSQMCG
                     RCHSGARVALQRRPAKEWEHLVNFHLGQWPSLEYQAQSRDRDWLDIALKQTVPDLAKRF
                     PLDSQAWTDWQKARPKADVLPGQWSFSGHMLAKGDVRGVMTVTADGADTFKVDVKGQYA
                     DGSPFTGSGSAILYNGYEWRGNVKVGDTTLRQVFAALDGQMTGRMFESEHDERGLDFSA
                     AKQGQARLLAVQPAQVKAGSETELTLVGSGLSGAPQLGAGLEVVKVLDSTPDHVRVKVK
                     AAADAAPGLREVSIGALKGVTLAVYKDIAEVKVVPAFSIARIGENGGSTPKVQGRFEAE
                     AWGTDAAGKAYRIGYLPAKWSVEPFDERAKEDEDVKFAGVMQKDGVFVPGGAGPNPERK
                     MMTNNAGNLKVIAELEEGGQKGEGHLIVTVQRWNNPPL"
     PFAM_domain     8452..8943
                     /aSDomain="Dehyd-heme_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09098.12"
                     /description="Quinohemoprotein amine dehydrogenase A, alpha
                     subunit, haem binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2491_0072"
                     /evalue="2.00E-73"
                     /label="ctg1_2491"
                     /locus_tag="ctg1_2491"
                     /protein_end="194"
                     /protein_start="30"
                     /score="245.6"
                     /tool="antismash"
                     /translation="GPALLQSKCMGCHIPEGNDTYSRISHQRKTPEGWLMSIARMQVMH
                     GLKISDEDRRTLVKYLADKQGLAPSETDGVRYAMERRLNTVEQFDDHLSQMCGRCHSGA
                     RVALQRRPAKEWEHLVNFHLGQWPSLEYQAQSRDRDWLDIALKQTVPDLAKRFPLDSQA
                     W"
     PFAM_domain     8977..9282
                     /aSDomain="Qn_am_d_aII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14930.8"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2491_0073"
                     /evalue="2.80E-38"
                     /label="ctg1_2491"
                     /locus_tag="ctg1_2491"
                     /protein_end="307"
                     /protein_start="205"
                     /score="130.5"
                     /tool="antismash"
                     /translation="VLPGQWSFSGHMLAKGDVRGVMTVTADGADTFKVDVKGQYADGSP
                     FTGSGSAILYNGYEWRGNVKVGDTTLRQVFAALDGQMTGRMFESEHDERGLDFSAAK"
     PFAM_domain     9292..9531
                     /aSDomain="Qn_am_d_aIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09099.12"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2491_0074"
                     /evalue="2.00E-21"
                     /label="ctg1_2491"
                     /locus_tag="ctg1_2491"
                     /protein_end="390"
                     /protein_start="310"
                     /score="76.2"
                     /tool="antismash"
                     /translation="ARLLAVQPAQVKAGSETELTLVGSGLSGAPQLGAGLEVVKVLDST
                     PDHVRVKVKAAADAAPGLREVSIGALKGVTLAVYK"
     PFAM_domain     9544..9921
                     /aSDomain="Qn_am_d_aIV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09100.12"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2491_0075"
                     /evalue="1.90E-46"
                     /label="ctg1_2491"
                     /locus_tag="ctg1_2491"
                     /protein_end="520"
                     /protein_start="394"
                     /score="157.3"
                     /tool="antismash"
                     /translation="VKVVPAFSIARIGENGGSTPKVQGRFEAEAWGTDAAGKAYRIGYL
                     PAKWSVEPFDERAKEDEDVKFAGVMQKDGVFVPGGAGPNPERKMMTNNAGNLKVIAELE
                     EGGQKGEGHLIVTVQRWNNPPL"
     CDS             10001..11431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Quinohemoprotein_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2492"
                     /sec_met_domain="PF04055 (E-value: 2.5e-13, bitscore: 49.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.7e-13, bitscore: 48.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.3e-14, bitscore:
                     50.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Quinohemoprotein_rSAM_RRE (E-value:
                     6.5e-26, bitscore: 88.6, seeds: 15, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAILNLVERNLHEVQVNTDRMLFHIPSSSLFATDALTGGIIDAL
                     RQQGCSPEELVQRLGGRFAGAEIDETLRELIALEVVSDGSPLTPEIGLKKVDRTALNTV
                     VLNVNTGCNLSCTYCYKEDLDKPSAGKKMAVETAEASVEMLLRESPDEARYSVVFFGGE
                     PLSNRPLIEHMVGYCERRFAAAGKQVEFVMTTNATLLTEEIVDWLNAHRFGLSISIDGP
                     KTVHDRNRITVGGQGTYDVVRRKVEMLLSRYTSRPVGARVTLTTGVTDVETIWDHLFNE
                     LGFAEVGFAPVTSGDISSFNLTADELVQVFANMKALGRRYLEAALENRNIGFSNLHQLI
                     TDIHEGQKKALPCGAGLKMLAVDHKGELNLCHRFTGSSLPTFGNVHGAVKQAELNDFLS
                     QRLDRTGTGCDSCRIRNLCSGGCYHESYARYGDPTHPTYHYCELMRDWVDFGIEVYSRI
                     LAGNPAFISRTITPRKAH"
     aSDomain        10028..11425
                     /aSDomain="TIGR03906"
                     /aSTool="tigrfam"
                     /description="quino_hemo_SAM: quinohemoprotein amine
                     dehydrogenase maturation protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2492_0027"
                     /evalue="1.50E-235"
                     /identifier="TIGR03906"
                     /label="ctg1_2492"
                     /locus_tag="ctg1_2492"
                     /protein_end="475"
                     /protein_start="9"
                     /score="780.1"
                     /tool="antismash"
                     /translation="RNLHEVQVNTDRMLFHIPSSSLFATDALTGGIIDALRQQGCSPEE
                     LVQRLGGRFAGAEIDETLRELIALEVVSDGSPLTPEIGLKKVDRTALNTVVLNVNTGCN
                     LSCTYCYKEDLDKPSAGKKMAVETAEASVEMLLRESPDEARYSVVFFGGEPLSNRPLIE
                     HMVGYCERRFAAAGKQVEFVMTTNATLLTEEIVDWLNAHRFGLSISIDGPKTVHDRNRI
                     TVGGQGTYDVVRRKVEMLLSRYTSRPVGARVTLTTGVTDVETIWDHLFNELGFAEVGFA
                     PVTSGDISSFNLTADELVQVFANMKALGRRYLEAALENRNIGFSNLHQLITDIHEGQKK
                     ALPCGAGLKMLAVDHKGELNLCHRFTGSSLPTFGNVHGAVKQAELNDFLSQRLDRTGTG
                     CDSCRIRNLCSGGCYHESYARYGDPTHPTYHYCELMRDWVDFGIEVYSRILAGNPAFIS
                     RTITPRKA"
     PFAM_domain     10328..10663
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2492_0076"
                     /evalue="2.40E-11"
                     /label="ctg1_2492"
                     /locus_tag="ctg1_2492"
                     /protein_end="221"
                     /protein_start="109"
                     /score="44.4"
                     /tool="antismash"
                     /translation="TGCNLSCTYCYKEDLDKPSAGKKMAVETAEASVEMLLRESPDEAR
                     YSVVFFGGEPLSNRPLIEHMVGYCERRFAAAGKQVEFVMTTNATLLTEEIVDWLNAHRF
                     GLSISIDG"
     aSDomain        11057..11323
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2492_0028"
                     /evalue="4.30E-14"
                     /identifier="TIGR04085"
                     /label="ctg1_2492"
                     /locus_tag="ctg1_2492"
                     /protein_end="441"
                     /protein_start="352"
                     /score="50.7"
                     /tool="antismash"
                     /translation="CGAGLKMLAVDHKGELNLCHRFTGSSLPTFGNVHGAVKQAELNDF
                     LSQRLDRTGTGCDSCRIRNLCSGGCYHESYARYGDPTHPTYHYC"
     CDS             11433..11756
                     /locus_tag="ctg1_2493"
                     /transl_table=11
                     /translation="MKHLKPLNQKAHLLEQAAAEDRLEEVVAMSAVAGCTATTDPGWEV
                     DAFGGVSSLCQPMEADLYGCSDPCWWPAQVPDMMTTYQDWNASAQDSSQDWRNLGTVFP
                     KDK"
     PFAM_domain     11523..11747
                     /aSDomain="QH-AmDH_gamma"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08992.13"
                     /description="Quinohemoprotein amine dehydrogenase, gamma
                     subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2493_0077"
                     /evalue="1.00E-43"
                     /label="ctg1_2493"
                     /locus_tag="ctg1_2493"
                     /protein_end="105"
                     /protein_start="30"
                     /score="147.3"
                     /tool="antismash"
                     /translation="AVAGCTATTDPGWEVDAFGGVSSLCQPMEADLYGCSDPCWWPAQV
                     PDMMTTYQDWNASAQDSSQDWRNLGTVFPK"
     CDS             11786..12907
                     /locus_tag="ctg1_2494"
                     /transl_table=11
                     /translation="MKLNAFASLAVAAGLALGGQALAADNAGLALKAGQEYMIATNYPN
                     NLHVLDLASDSLYKTCRLPDAFGPGTAMVSPDRKTAYLLNNHFGDLYGIDLDSCRAVFH
                     AKLSRKPDEKARSMFAFALSPDGKELYSVVNPTRMASDHYEVQQPRLEVFDTAAGLDAQ
                     PVRSFPVPRQLYIMRAADDGTLYIAGPDIYKMDVKTGHYEVAVPGRNWKRPNYGPPDVL
                     YFWPHQTPLHEFSMLYTTTRFKDEKQDPATADFVYGYVSIDLKTGKPTVEDFAPLTELY
                     FTGLRSPKDPNQMFGVLNRLAKYDIKQQKLIKAANLDHSYYCIAFNTQGSKLYLAGTFN
                     DIAVFDPDSLEKVKNIKLPGGDMAITTTQVFVR"
     aSDomain        11888..12904
                     /aSDomain="TIGR03907"
                     /aSTool="tigrfam"
                     /description="QH_beta: quinohemoprotein amine
                     dehydrogenase, beta subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2494_0029"
                     /evalue="1.30E-156"
                     /identifier="TIGR03907"
                     /label="ctg1_2494"
                     /locus_tag="ctg1_2494"
                     /protein_end="373"
                     /protein_start="34"
                     /score="518.9"
                     /tool="antismash"
                     /translation="QEYMIATNYPNNLHVLDLASDSLYKTCRLPDAFGPGTAMVSPDRK
                     TAYLLNNHFGDLYGIDLDSCRAVFHAKLSRKPDEKARSMFAFALSPDGKELYSVVNPTR
                     MASDHYEVQQPRLEVFDTAAGLDAQPVRSFPVPRQLYIMRAADDGTLYIAGPDIYKMDV
                     KTGHYEVAVPGRNWKRPNYGPPDVLYFWPHQTPLHEFSMLYTTTRFKDEKQDPATADFV
                     YGYVSIDLKTGKPTVEDFAPLTELYFTGLRSPKDPNQMFGVLNRLAKYDIKQQKLIKAA
                     NLDHSYYCIAFNTQGSKLYLAGTFNDIAVFDPDSLEKVKNIKLPGGDMAITTTQVFVR"
     CDS             13131..14831
                     /NRPS_PKS="Domain: AMP-binding (23-456). E-value: 2.1e-103.
                     Score: 337.9. Matches aSDomain:
                     nrpspksdomains_ctg1_2495_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     427.9; E-value: 7e-130)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2495"
                     /sec_met_domain="AMP-binding (E-value: 1.3e-110, bitscore:
                     368.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHQPSYTRGRQDKPLLAMTIGAAFDATVARFPEREALVVRHQGLR
                     YSWRSLAEAVEAHARALMALGIQSGDRLGIWAPNCAEWCITQFASAKVGAILVNINPAY
                     RSSELEYALRQSGCRWVICADAFKTSDYHAMLQGLVPELASAPIGQLASEALPELRGVI
                     SLAAEPPAGFLAWADLQQRAGEATPAELAERQASLQFDDPINIQYTSGTTGFPKGATLS
                     HYNILNNGYMVGESLGLTEHDRLVIPVPLYHCFGMVMGNLGCVTHGATMIYPGDAFDPL
                     TALRAVAEEKATVLYGVPTMFIAELDHPQRHEFDLSSLRTGIMAGATCPIEVMRRVIGE
                     MHMSEVQIAYGMTETSPVSLQTGPDDGLELRVTTVGRTQPQLESKIVDAEGRIVPRGTI
                     GELCTRGYSVMLGYWNNPQATADAIDPGRWMHTGDLAAMDDDGYVRIVGRSKDMIIRGG
                     ENIYPRELEEFFFTHPAVADVQVIGIPCSKYGEEIVAWIKFHPGHSAGEEELKTWAKAR
                     IAYFKVPRHFRFVDEFPMTVTGKIQKFRMREISIEELTPPRDGKVTAIR"
     aSDomain        13200..14498
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2495_AMP-binding.1"
                     /evalue="2.10E-103"
                     /label="ctg1_2495_AMP-binding.1"
                     /locus_tag="ctg1_2495"
                     /protein_end="456"
                     /protein_start="23"
                     /score="337.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FDATVARFPEREALVVRHQGLRYSWRSLAEAVEAHARALMALGIQ
                     SGDRLGIWAPNCAEWCITQFASAKVGAILVNINPAYRSSELEYALRQSGCRWVICADAF
                     KTSDYHAMLQGLVPELASAPIGQLASEALPELRGVISLAAEPPAGFLAWADLQQRAGEA
                     TPAELAERQASLQFDDPINIQYTSGTTGFPKGATLSHYNILNNGYMVGESLGLTEHDRL
                     VIPVPLYHCFGMVMGNLGCVTHGATMIYPGDAFDPLTALRAVAEEKATVLYGVPTMFIA
                     ELDHPQRHEFDLSSLRTGIMAGATCPIEVMRRVIGEMHMSEVQIAYGMTETSPVSLQTG
                     PDDGLELRVTTVGRTQPQLESKIVDAEGRIVPRGTIGELCTRGYSVMLGYWNNPQATAD
                     AIDPGRWMHTGDLAAMDDDGYVRIVGRSKDMIIR"
     PFAM_domain     13200..14498
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2495_0078"
                     /evalue="3.60E-106"
                     /label="ctg1_2495"
                     /locus_tag="ctg1_2495"
                     /protein_end="456"
                     /protein_start="23"
                     /score="355.4"
                     /tool="antismash"
                     /translation="FDATVARFPEREALVVRHQGLRYSWRSLAEAVEAHARALMALGIQ
                     SGDRLGIWAPNCAEWCITQFASAKVGAILVNINPAYRSSELEYALRQSGCRWVICADAF
                     KTSDYHAMLQGLVPELASAPIGQLASEALPELRGVISLAAEPPAGFLAWADLQQRAGEA
                     TPAELAERQASLQFDDPINIQYTSGTTGFPKGATLSHYNILNNGYMVGESLGLTEHDRL
                     VIPVPLYHCFGMVMGNLGCVTHGATMIYPGDAFDPLTALRAVAEEKATVLYGVPTMFIA
                     ELDHPQRHEFDLSSLRTGIMAGATCPIEVMRRVIGEMHMSEVQIAYGMTETSPVSLQTG
                     PDDGLELRVTTVGRTQPQLESKIVDAEGRIVPRGTIGELCTRGYSVMLGYWNNPQATAD
                     AIDPGRWMHTGDLAAMDDDGYVRIVGRSKDMIIR"
     CDS_motif       13746..13799
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2495_0001"
                     /evalue="1.40E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2495"
                     /protein_end="223"
                     /protein_start="205"
                     /score="17.8"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGATLSH"
     CDS_motif       14313..14399
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2495_0002"
                     /evalue="1.00E-09"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg1_2495"
                     /protein_end="423"
                     /protein_start="394"
                     /score="30.6"
                     /tool="antismash"
                     /translation="PRGTIGELCTRGYSVMLGYWNNPQATADA"
     PFAM_domain     14523..14750
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2495_0079"
                     /evalue="3.30E-15"
                     /label="ctg1_2495"
                     /locus_tag="ctg1_2495"
                     /protein_end="540"
                     /protein_start="464"
                     /score="56.9"
                     /tool="antismash"
                     /translation="ELEEFFFTHPAVADVQVIGIPCSKYGEEIVAWIKFHPGHSAGEEE
                     LKTWAKARIAYFKVPRHFRFVDEFPMTVTGK"
     CDS             14923..15948
                     /locus_tag="ctg1_2496"
                     /transl_table=11
                     /translation="MTGTSAEKGTISVRLVDEALQVLRQQGGDVAALLEQAGIPAEQMA
                     RPYGRVASRQYAQLWLLIARVMDDEFFGMDSRRLKSGSFAHMSRTALQAATLGDALQAS
                     LTFLALVLDDLQPRLARRGSLAEIVLDDSGAPPRAFACFTLFLMVHGLLCWLAGRRLPI
                     LGIELRGPQPAYIEDYRVMFTPHLRFGRDTTRLVFNADCLAQPVRRNEADLRRFLAGAP
                     ANILVRYRDPQSLAARIKTYLRSLRPERWPDLEALSGHFYMAPSTLRRKLTQEGQSYQA
                     LKDQVRRDLAVARLDAGEVNFTELAFELGFADASAFYKAFRKWTGSTPGQYRALVHPEA
                     G"
     PFAM_domain     15001..15543
                     /aSDomain="Arabinose_bd"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12625.9"
                     /description="Arabinose-binding domain of AraC
                     transcription regulator, N-term"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2496_0080"
                     /evalue="7.50E-46"
                     /label="ctg1_2496"
                     /locus_tag="ctg1_2496"
                     /protein_end="207"
                     /protein_start="26"
                     /score="156.6"
                     /tool="antismash"
                     /translation="GGDVAALLEQAGIPAEQMARPYGRVASRQYAQLWLLIARVMDDEF
                     FGMDSRRLKSGSFAHMSRTALQAATLGDALQASLTFLALVLDDLQPRLARRGSLAEIVL
                     DDSGAPPRAFACFTLFLMVHGLLCWLAGRRLPILGIELRGPQPAYIEDYRVMFTPHLRF
                     GRDTTRLVFNADCLAQPV"
     PFAM_domain     15697..15924
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2496_0081"
                     /evalue="2.30E-15"
                     /label="ctg1_2496"
                     /locus_tag="ctg1_2496"
                     /protein_end="334"
                     /protein_start="258"
                     /score="56.7"
                     /tool="antismash"
                     /translation="GHFYMAPSTLRRKLTQEGQSYQALKDQVRRDLAVARLDAGEVNFT
                     ELAFELGFADASAFYKAFRKWTGSTPGQYRA"
     CDS             complement(15955..16380)
                     /locus_tag="ctg1_2497"
                     /transl_table=11
                     /translation="MQLAPFHLAIPVHDLPAARRFYGEVFGLAEGRSSAQWVDFDFFGH
                     QLVIHEHPPTTSQLAAHTNPVDGHDVPVPHFGVVLAWEDWEALAERLQRLGTRFVIEPY
                     VRFKGQVGEQATLFLLDPCGNALEFKAFRDIGQLFAK"
     PFAM_domain     complement(15994..16362)
                     /aSDomain="Glyoxalase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00903.27"
                     /description="Glyoxalase/Bleomycin resistance
                     protein/Dioxygenase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2497_0082"
                     /evalue="8.40E-08"
                     /label="ctg1_2497"
                     /locus_tag="ctg1_2497"
                     /protein_end="129"
                     /protein_start="6"
                     /score="32.6"
                     /tool="antismash"
                     /translation="HLAIPVHDLPAARRFYGEVFGLAEGRSSAQWVDFDFFGHQLVIHE
                     HPPTTSQLAAHTNPVDGHDVPVPHFGVVLAWEDWEALAERLQRLGTRFVIEPYVRFKGQ
                     VGEQATLFLLDPCGNALEF"
     CDS             16484..17353
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 170.2; E-value: 9.5e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2498"
                     /transl_table=11
                     /translation="MLREIRTFVAVARHGTFAAAGMHIGLTQSAVSAQIRNLEEALGVR
                     LFDRTGRQALLNAAGERALPLAREMLDLFARMAATDEAGAHAGELRIGAIATAQTGLLA
                     DALLRLRERAPAVEPKLVPGVSLNLLSQVDAGDLDLAILIRPPFELPKELHAEVLREEA
                     FVLVVPRGLEGDDPLRLLAEQPLVRYDRTSFGGRLVTRFLRQQRLDVKVALELDELDAI
                     VRMVEAGLGIALIPEAGLWLERDAAIRVVRLGPLTFHRQIILLTRHAQRRQPLQRLFAA
                     CLAGEDAK"
     PFAM_domain     16487..16666
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2498_0083"
                     /evalue="1.90E-20"
                     /label="ctg1_2498"
                     /locus_tag="ctg1_2498"
                     /protein_end="61"
                     /protein_start="1"
                     /score="72.7"
                     /tool="antismash"
                     /translation="LREIRTFVAVARHGTFAAAGMHIGLTQSAVSAQIRNLEEALGVRL
                     FDRTGRQALLNAAGE"
     PFAM_domain     16736..17335
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2498_0084"
                     /evalue="6.00E-37"
                     /label="ctg1_2498"
                     /locus_tag="ctg1_2498"
                     /protein_end="284"
                     /protein_start="84"
                     /score="127.2"
                     /tool="antismash"
                     /translation="AHAGELRIGAIATAQTGLLADALLRLRERAPAVEPKLVPGVSLNL
                     LSQVDAGDLDLAILIRPPFELPKELHAEVLREEAFVLVVPRGLEGDDPLRLLAEQPLVR
                     YDRTSFGGRLVTRFLRQQRLDVKVALELDELDAIVRMVEAGLGIALIPEAGLWLERDAA
                     IRVVRLGPLTFHRQIILLTRHAQRRQPLQRLFAACLA"
     CDS             complement(17361..19439)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 64; E-value: 2.6e-19)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2499"
                     /transl_table=11
                     /translation="MDATPFPAAPGPMSQQVRQHDWSRTPLGPIEHWPEALRISVDTIL
                     SSHFPCCLVWGPQRISIYNDGFVPILGNKHAPLGRPFDDIWREAWDSIGPIAERAYQGQ
                     ATFIEDFPVELDRHGRPEMSYFTFCYSPLRDADGRVLGMLDTVIETTSRVTAERQLRQL
                     THNLERQVAERTRDRNRLWNLSPDIMLVSRQDLVITAANPATQNILGWSEAELVGSNCL
                     DLVHPDDLADAWAAIHSLIQGEPLRDYASRMRHRDGSYRWINWSSSSGDGFISAIGRDT
                     TEERARADALRQAEEQLRQSQKMEAVGQLTGGLAHDFNNLLAGISGSLELLRLRIAQGR
                     TEDLNRYIDIARSAAERAATLTHRLLAFSRRQALDPRPTDVNQLVATLHELISRTMGPN
                     IEVECVDGPDLWTVLVDPNQLESALLNICINARDAMPNGGRLCIGSNNVVLGAQAAGER
                     GLEPGDYLVLMVSDTGSGMSEDVISRAFEPFFTTKPVGQGTGLGLSMVYGFARQSGGQV
                     RIASTLGQGTSLSLYLPRHHGEAEPAPTPRPVEIPRAEQCTTVLVVDDEAPLRQLMREV
                     LEDLGYQMLEAADGPGALALLAGERAVDLLLADVGLPGGLNGLELARRARLQRPDLKVL
                     FITGYAQNAPFGNEPLPPGMEVMAKPYAIDALANRIRLLLKAPPSGQPPAEAGLRAV"
     PFAM_domain     complement(17427..17762)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2499_0088"
                     /evalue="2.10E-16"
                     /label="ctg1_2499"
                     /locus_tag="ctg1_2499"
                     /protein_end="671"
                     /protein_start="559"
                     /score="60.2"
                     /tool="antismash"
                     /translation="VLVVDDEAPLRQLMREVLEDLGYQMLEAADGPGALALLAGERAVD
                     LLLADVGLPGGLNGLELARRARLQRPDLKVLFITGYAQNAPFGNEPLPPGMEVMAKPYA
                     IDALANRI"
     PFAM_domain     complement(17835..18194)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2499_0087"
                     /evalue="1.30E-15"
                     /label="ctg1_2499"
                     /locus_tag="ctg1_2499"
                     /protein_end="535"
                     /protein_start="415"
                     /score="58.0"
                     /tool="antismash"
                     /translation="DPNQLESALLNICINARDAMPNGGRLCIGSNNVVLGAQAAGERGL
                     EPGDYLVLMVSDTGSGMSEDVISRAFEPFFTTKPVGQGTGLGLSMVYGFARQSGGQVRI
                     ASTLGQGTSLSLYLPR"
     PFAM_domain     complement(18321..18518)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2499_0086"
                     /evalue="5.60E-10"
                     /label="ctg1_2499"
                     /locus_tag="ctg1_2499"
                     /protein_end="373"
                     /protein_start="307"
                     /score="39.2"
                     /tool="antismash"
                     /translation="GQLTGGLAHDFNNLLAGISGSLELLRLRIAQGRTEDLNRYIDIAR
                     SAAERAATLTHRLLAFSRRQA"
     aSDomain        complement(18585..18917)
                     /aSDomain="TIGR00229"
                     /aSTool="tigrfam"
                     /description="sensory_box: PAS domain S-box protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2499_0030"
                     /evalue="1.00E-14"
                     /identifier="TIGR00229"
                     /label="ctg1_2499"
                     /locus_tag="ctg1_2499"
                     /protein_end="285"
                     /protein_start="174"
                     /score="52.7"
                     /tool="antismash"
                     /translation="TRDRNRLWNLSPDIMLVSRQDLVITAANPATQNILGWSEAELVGS
                     NCLDLVHPDDLADAWAAIHSLIQGEPLRDYASRMRHRDGSYRWINWSSSSGDGFISAIG
                     RDTTEER"
     PFAM_domain     complement(18639..18842)
                     /aSDomain="PAS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08447.14"
                     /description="PAS fold"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2499_0085"
                     /evalue="2.10E-13"
                     /label="ctg1_2499"
                     /locus_tag="ctg1_2499"
                     /protein_end="267"
                     /protein_start="199"
                     /score="50.5"
                     /tool="antismash"
                     /translation="AANPATQNILGWSEAELVGSNCLDLVHPDDLADAWAAIHSLIQGE
                     PLRDYASRMRHRDGSYRWINWSS"
     CDS             complement(19564..20070)
                     /locus_tag="ctg1_2500"
                     /transl_table=11
                     /translation="MATYRELFDIGQSYTEFVGSGLPAETAAAAAIAQRLEDQGPAAPL
                     LQRIEQIERRYHLLVVGEMWCPDCQINVTVLDDLCRRQPRIDLAVITKGRAEDDLKTRL
                     GLERIAIPLVVVLDEAFEPAGLFIERPRLVREGDEAVLRAYKAGEHLDATLADVLELIE
                     QAEQR"
     PFAM_domain     complement(19663..19941)
                     /aSDomain="Thioredoxin_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14595.8"
                     /description="Thioredoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2500_0089"
                     /evalue="3.20E-20"
                     /label="ctg1_2500"
                     /locus_tag="ctg1_2500"
                     /protein_end="136"
                     /protein_start="43"
                     /score="72.3"
                     /tool="antismash"
                     /translation="PLLQRIEQIERRYHLLVVGEMWCPDCQINVTVLDDLCRRQPRIDL
                     AVITKGRAEDDLKTRLGLERIAIPLVVVLDEAFEPAGLFIERPRLVRE"
     CDS             complement(20135..21019)
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 199.3; E-value: 1.3e-60)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_2501"
                     /transl_table=11
                     /translation="MHFDLSDLRLLSAIAATGSLSKAAATFPVAVSAASTRLRQFESRC
                     GITLFTRRADGMTPTPSGRLVLERCHALLNEAQGLKVLLEELAGQQRVVVHLAATTVAN
                     SSFLPGALGPFLADYPEVDLQLTEQTSRDVLRGVQAGDIDIGVYDGNLPTGGLISLPFR
                     DDRLVMLVPAGHALAPLRSVHLRDTLGYPFVCLPAERSMQRFVEEMARQNGLPLMVRVR
                     APSFDAIAQLVAQGAGIAMLPEAAAHRLTQELPVAIVTLEDTWATRELRLCIRGTDGLG
                     SHARQLLGYLSPG"
     PFAM_domain     complement(20147..20752)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2501_0091"
                     /evalue="2.60E-40"
                     /label="ctg1_2501"
                     /locus_tag="ctg1_2501"
                     /protein_end="291"
                     /protein_start="89"
                     /score="138.2"
                     /tool="antismash"
                     /translation="QQRVVVHLAATTVANSSFLPGALGPFLADYPEVDLQLTEQTSRDV
                     LRGVQAGDIDIGVYDGNLPTGGLISLPFRDDRLVMLVPAGHALAPLRSVHLRDTLGYPF
                     VCLPAERSMQRFVEEMARQNGLPLMVRVRAPSFDAIAQLVAQGAGIAMLPEAAAHRLTQ
                     ELPVAIVTLEDTWATRELRLCIRGTDGLGSHARQLLGYL"
     PFAM_domain     complement(20828..21004)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2501_0090"
                     /evalue="3.20E-13"
                     /label="ctg1_2501"
                     /locus_tag="ctg1_2501"
                     /protein_end="64"
                     /protein_start="5"
                     /score="49.5"
                     /tool="antismash"
                     /translation="SDLRLLSAIAATGSLSKAAATFPVAVSAASTRLRQFESRCGITLF
                     TRRADGMTPTPSGR"
ORIGIN
        1 gcagtggcca tgccgaccac ccgggcgcgg gccttgaggc cgtggcgccg ggcggcggcg
       61 gggctggcca gcagcagggc acaggcgccg tcgttgacgc ccgaggcgtt gccggcggtg
      121 accgaaccgc ccgggcggaa gggcgtgccc agtttggcca gttgctccag ggtggtatcg
      181 ccgcgcgggt gctcgtcctg gctcaccacc ttgggcgggc ctttgcgctg ggggatttcc
      241 acggggacga tctctttgcc caggcgcccg ctggcctggg ccgcggcggc gcgctgctgg
      301 ctgcgcaggg cgaaggcgtc ctggtcggcg cgggagatgc cgaactgctc ggcgacgttc
      361 tcggcggtct ccggcatgga gtcgatgccg aatccggcct gcatcagcgg gttgacgaag
      421 cgccagccga tggtggtgtc gaagatctcc gcctggcggg agaaggcggt gtcggccttg
      481 cccatgacga agggcgcgcg ggacatggac tccaccccgc cggcgatcat cagtccggct
      541 tcgccgcagc gcagggcgcg ggcggcgctg cccacggcgt cgaggccgga gccgcacagg
      601 cggttgaggg tggtgccggg cacgctctgc ggcaggccgg cgagcagggc ggccatgcgc
      661 gcgacgttgc ggttgtcctc gccggcctgg ttggcgcagc cgtagatcac gtcgtcgatg
      721 gcgctccagt ccagttccgg gtggcgcgcc atcagggcgc ggatcggcac cgcgccgaga
      781 tcgtcggcac gcacgccgga cagcgccccg gcgtagcggc cgatgggggt gcgcacggcg
      841 tcgatgatca gggcgtcgtt catctggaca tcactcatca ggggtctcct gcgcgagcac
      901 cgtgccgcgc actttgtagg atttgccgtg gaacagggcg atcagctgcc cgttctggtt
      961 ctcgatgcgc acgtcgtagt tgccggtgcg cccgctgcgg ctctgctcgc tggcctgggc
     1021 ggtgagggtg tcgcccaggc gcgccggggc cacgtagtcg atgctgcagc cgatggccac
     1081 ggtggcttcg ttgtagctgt tgcaggcgaa ggcgaaggcc gagtcggcca gggcgaagag
     1141 gtagccgccg tggcaggtgc cgtggccctg gaccatgtcg gcgcgcacgg tcatgcccat
     1201 ctgcgcctgg ccgggtgcga cggagagcag gcgcatgccc atggcctggc tggcggtgtc
     1261 gcgctcgaac agggcgctgc cgcaggcctc ggccagggac agggcttcat ggttggtcat
     1321 ggaaggtcct cccttcggcg acgtggcggc gcagcagcag cgacgggcga tagcgcgcct
     1381 cgccgtaggc cacctgcagg ttgtccaggg tgcgcagcag cgccgccagg ccgatggcgt
     1441 ccgcccaggc cagcgggccc ttggggtagt tgacgccagc gcgcatggcc aggtcgatgt
     1501 ccgccgccga gccgacgccc tgcagcaccg catcggcgcc ttcgttggcc agcatggcga
     1561 cggtgcgcag cacggccagg ccggggatgt cggccaacgg cgtggcggtg atgccggcgc
     1621 gctgcagcag tgccacggcc tggtcgcggg cgagggcgga ggtgctggcg gcccaggtga
     1681 tgcccaggcg gctggcctcg gcgtagtcca gcgccaggtc cagcagcacc aggttggcca
     1741 ggccgtcctc acgggcgcgc tggctggcca ggcggccgtc ggagagggcc agcacggcat
     1801 cgccgacccg cagcaggccg gtgccgtcac ggcgggtcac cgccaggccg gcggcctgca
     1861 ggcgcgccgc cagcggctcg gccacgccca ggtggccctc caccacgcag ccgtccacgg
     1921 tctgctcgct ggagagcgcg gcgggcgtcg ggcgctgggc gccctcggcg tagtcgtaga
     1981 agccacggcc gctcttgcgc ccgaggcggc cggcgtccac cagctccttc tggatcagcg
     2041 agggctggaa gcggaagtcg ccgtagtagg cctcgaacac cgagcaggtg acggcgtagt
     2101 tgacgtcgtg gccgatcagg tcggtgagtt cgaaggcgcc catgcggaag ccgccggcct
     2161 cgcgcatcag ggcgtcgagg gtggcgcagt cggcggcacc ctcctgcagc aggcgcaggc
     2221 tttccgcata gaagggccgg gccacgcggt tgacgatgaa gccgggggtg gagcgggtgt
     2281 gcaccggctg cttgccccag gcacgcgcag tggcgtacag ggcgtcagcc agggccgggt
     2341 cgctggccag gcccgagacg acttccacca gggccatcag cggtgccggg ttgaagaaat
     2401 gcaggccgat cacccgcccc gggtgggcga gcccggcggc cagggcggtg atggacagcg
     2461 aggaggtgtt gctggcgagg atgcaggtgg ggctgcacag cgcctccaac tgctgtagca
     2521 gggcgcgctt gatctccagg ttctcgacga tggcttcgat caccaggcgt gcgtcggcca
     2581 gggcttccag cgtctccgcc ggttgcaggc gggcgacgat ggcctggcgc tcggcggcat
     2641 ccagcttgcc tttctccacc aggcggccga gctggcggtc gatgccgtcc acggcctggg
     2701 cggcggcgcc gggtcggttg tcgtagagcc ggaccgggtg gccggcctgg gccgccacct
     2761 gggcgatgcc ggcgcccatg gcaccggcgc cgatcacggc gacgagggac gtttggggca
     2821 gggcgggcat gggctcagcg tcctttgaag accggggtgc gtttggccat gaaggcgctg
     2881 acgccttcgc ggtagtcctc gctgcggccg gccaggcgct gcaggtcgcg ctccagttcc
     2941 agctgctggt cgaagctgtt gtccaggctg gcattgaggc tgcgcttgat cagcgccagg
     3001 ccgtaggtcg gctgggtggc caggtggcgg gcgagcttga gggcctcgtc acgcagggcg
     3061 gcatcgtcca ccacgcggtg gatcagcccc cactgctcgg cctgctcggc gctcaggcgc
     3121 tcgcccagca gggccagggc cttggcgcgg gccatgccca ccaggcgcgg cagggtccag
     3181 gtgccgccgg aatcggggat cagaccgatc ttgcagaagg cctggatgaa gctggcggag
     3241 cgggcggcca ggaccaggtc gcacgccagg gggatgttgg ccccggcccc ggcggcgacg
     3301 ccgttgacgg cgcagaccac cggcatgggc aggtcgcgca gggtgcggat cagcgggttg
     3361 tagaactgct cgatggaggt acccaggtcc ggcgcctcgc tgccgggggc gacgttgcgg
     3421 tcggccaggt cctggccggc gcagaagcca cggccttcgc cggtcagcag cagcacgcgc
     3481 accgccgggt cctggcgcac ctgcttgagg gcctcgcgga cctcgccgtg catctgggcg
     3541 ttgaagctgt tgagctgctc gggtcggttg aggctgaggg tggcgacacc cgcctcgatg
     3601 gaaaagagga tgtgttcgaa ggtcatgtct cgggcgctcc agggcggcgg gagagggcgg
     3661 ccagcggtca ctggccggtg aagtcggggc ggcgcttttc ctggaaggca cggatgcctt
     3721 cgtcgcggtc gcgggtgccg gccagcaggg tgaaggcatg gcgctcgaag cgcaggccgc
     3781 tggcgaggtc ggtgtcctcg gccttgagca cggcctcttt agccaggcgc acggccagtg
     3841 gcgctttctg ggcgatcagc cgggcgatgg cgagggcgcg ctcgacggtg aactcgggtt
     3901 gggtcacctc gctgaccagc ccggcgcgca gggcgtggcg ggcgtcgatg gcttcgccgg
     3961 tgagcaccat ctgcatggcc agggacttgc ccacggcgcg cagcaggcgc tgggtgccgc
     4021 cggcgccggg catgatcccg aggttgattt ccggctggcc gaagcgggcg tcttcaccgg
     4081 cgatgaggat gtcggcgtgc atggccagct cgcagccacc gccgaggcag aagccgttga
     4141 cggcggccac cagcggtttg ccgaagcgtg cgatgcgttg ccagtgggcc tggcgcgggt
     4201 cgttgaggat gcccaccagg tcgcgctcgg ccatctcctg gatgtcggca ccggcggcga
     4261 aggccctgcg gctgccggtg atcaccaccg cgcgggtgtc ggcgtcctgc tcggccaggt
     4321 ccagctcggc agccagttcg ccgagcagct cggtgttcag cgcattcagc gcctcggggc
     4381 gctgcagggt gatcaggcgg acacccagtt cgggcggcag gacagcaagg gtacgaggca
     4441 tgacgaacgt cctctggtgc acgcgcggct caggcatgcc gctcttgttg gtgagatggc
     4501 gcgtgacccg ggcgttcgcg acgggtcgcc atccgttgtg gcggcagtat aggcataaag
     4561 cgatacaaaa caacaaatct aaaaatagaa aatgtgtctt aaaagatcgc ggcttggtgg
     4621 ttgtgaaggg tctgctacag ggcttatcgg cctttaatta gcgttgagtg gctgattggt
     4681 cgtgattctg gtgctttttt gaaggtgttt ccatgtgata caagagctgt gtatttttga
     4741 atcgaataag gcttgagcct gagaaggaga aacgcccatg gcctgctaca gcctggatgg
     4801 actggttccg gtggtgcacc ccactgccta tgtgcacccg agcgcggtgc tgatcggtga
     4861 cgtgatcatc ggcccgcact gctacgtcgg cccgctggcc agcctgcgcg gcgatttcgg
     4921 gcgcatcgtt ctggaggagg gcgccaacat ccaggacacc tgtgtgatgc acggcttccc
     4981 cggcagcgac acggtggtgg cgcgcaacgg ccacatcggg cacggcgcgg tgttgcatgg
     5041 ctgccagatc ggcgaagacg ccctggtggg catgaatgcg gtggtgatgg atggcgcgcg
     5101 catcggcgcg cgttccttcg tttccgccac ggccttcgtc aaggcgggtt tcacctgcga
     5161 tgcgcagtcc ctggtgatgg gctccccggc gcaggtgcgc cgtgtgctga gcgatgacga
     5221 ggtggcctgg aaacaggccg gcacccgcga gtaccagcgc ctggcccagc gctgcctggc
     5281 ggcgctcgag ccctgcgagc cgctggccga ggtggagccc ggccggccgc gcatgagcga
     5341 tccgggcctg cggcccaagg gcgaggcaca ctgatgggtt cggtctgtgg ccccctaacg
     5401 cctgtggccc catcgtgaag cgtgcgggta tagtcggcat cccttaacga ccccgtatgc
     5461 ccatgacctc cctcgcgccc ctggaccagc tcatcacccg cttccagcag cagactccca
     5521 ttcgcgccag ctcgctgatc atgaccctct acggggatgc catcgaaccc cacggcggca
     5581 ccgtctggct gggcagcctg atccagatgc tggaacccat cggcatcaac gaacggctga
     5641 tacgcacctc gatcttccgc ctcaccaagg acggctggct gagtgccgag aaggtcgggc
     5701 ggcgcagcta ctacagcctc accggcacgg gtcgtcggcg tttcgagaag gccttcaagc
     5761 gcgtctacag ctccggcatc ccggcctggg atggctcctg gcacctggtg gtgctgtcgc
     5821 agctgcccca ggagaagcgc aagcaggtgc gcgaggagct ggagtggcag ggcttcggcg
     5881 ccatcgcgcc gaccgtgctg gccaaccccc gctgcgaccg cgtggacctc accaccaccc
     5941 tgcaggagct ggacgccctg gaggacagca tcgtcttcga gaccagcgcc caggatgtgc
     6001 tggcctccaa ggccctgcgc atgcaggtgc gcgagagctg gcggctggac gaactgggcg
     6061 agcactaccg cgagttcatc cagctgttcc gcccgctctg gcaggccctg cgcgagcagg
     6121 aaagcttgga cccggaggac tgcctgctgg cccgcacgct gctgatccac gaataccgcc
     6181 gcctgctgct gcgcgacccg caactgccgg acgaactgct gcccagcgac tgggaaggcc
     6241 gctcggcacg ccagctgtgc cgcaacatct accgcctgat ctacgccaag gccgaggaat
     6301 ggctgaacgc caacctggaa accgccgacg gcccgctgcc cgacgccagc gagggcttct
     6361 accggcgctt tggcggtctg cgctagcacg ctgaacgagg tgggcaggcc ggccgcctgc
     6421 ccagtcttgt gccggcccct gccttggggc cggcgttgcg cttacaaccg catcagcacc
     6481 gacttgagtt cggtgtagtg ctcgatggcg gctgcgccca tctcgcggcc gagccccgac
     6541 atcttgtagc cgccgaaggg cagggccggg tccaatgcgc tgtggcagtt gacccacacg
     6601 gagccggact tgatgcgcgg gatcatccgg tgcacggcgc ccaggtcgtt ggaccagatg
     6661 ctcgcgccga ggccgtaggg gttgtcgttg gccaggcgca cggcttcgtc gaggtcgtcg
     6721 aagggcatgg ccaccagcac cgggccgaag atctcttcct gcaccaggcg gtgcttctgg
     6781 tcgacgtcgg cgatcaccgt cggcttgacg aaataccccg gcccgaagcc ttcgccgccg
     6841 cagaccaccg acgcccccag ctcgcggccg aggttgatgt agccggtcac gcggtcctgc
     6901 tggcgggcgg agatcagcgg gcccatctgc acgctcgggt ccagcccgtt gcccagcttc
     6961 atgccgttgg cgatgccggc gatgtcggcc accacgttgt cgaagtgctt gcgctgcacg
     7021 tacaggcgcg agccggcgca gcacacctgg ccctggttga agaagatcgc cgtggcggcg
     7081 ccggcggcgg cgtcctgtag gttggcgtcg gccagtacca gggtgggcga cttgccaccc
     7141 agctccaggg tgacgcgggt catgttgtcc atggcggctt tgccgatctg cttgccgacc
     7201 tcggtggagc cggtgaaggt cagcttgtcc acgcccgggt ggcgggtgag ggcggcgccg
     7261 gcgttcaggc cggtgccggt caccacgttg aacaccccgg cggggtagcc cgcctccagc
     7321 accagttcgg ccagcttgag ggcggtaacc ggcgtttcgt ccgccggctt gagcaccacc
     7381 gtgcagccgg tggccagggc cgggccgagc ttccagcagg ccagcagcag ggggaagttc
     7441 caggcgacga tggcgcccac cacgccgacg gcttcgcggc ggatgaaacc gtggaactgg
     7501 tcgtccggca tcagcggcag ggagacgtcg acgctgctgc cttcgatctt ggtggcccag
     7561 ccggccatgt agcggaggaa gtcgatggcc agttgcacgt ccatcacctg cgccaccgcc
     7621 gcgctcttgc cgttgttcag gcattccagc tccgccagtt gctgggcatc gcgctgcatc
     7681 aggtcggcca ggcgccacag caggttctgc cgttcgcggg ggcgcatgcg gctccaggcg
     7741 gagtcatcga aagcctggcg ggcggcgcgc acggcacggt ccacgtcgtc cgcgtcggcc
     7801 gaaggcacgc ggccgatgac gtcacccgtg gccgggttgc ggaagtctag ggtggcgccg
     7861 ctggtggcgt cctgccactg gtcgccgatg agcatcttca gcgggcggtc gaggaaggcg
     7921 cgggtggccg gcaggagggg cagctggtcg gacatgggtt cgctctcttg ttgtcaggga
     7981 aggaggtgac agccatgggg caaccgccat gccaagctgc gcgcgagggc gccaggcgcc
     8041 gtctgccgtg acctgcggcg acgatgaggt gggcaccggc gcattggggc tgttgcactt
     8101 tgagacggcg tgagacaacc cgtgcaacag ccgcgcccgc tgcgctcggg tgtcaccgtg
     8161 gcggcgtctc aggctggaac agcctgtctc gaaattagac gcgtgcggtg tttcgccaca
     8221 gccccgatga agccgcgttg cgcgctcaag gcattgattt agaaaggttt atcggaagtg
     8281 gcacacatcc tgtatcggct gcgacagttg tgccgcccgg ttcggcgcga cccataagaa
     8341 caaaaccgtg gaggtctgac cttgaagacg actcgactcc ggcggcaagc gggcagcctg
     8401 gtgctgaccc tggcagcctt gctgtgtgcc caggcccatg gggcggaaga ggggccggcg
     8461 ctcctccagt ccaaatgcat ggggtgccac atccccgagg gcaacgacac ctacagccgc
     8521 atcagccacc agcgcaagac gcccgaaggc tggctgatga gcatcgcccg catgcaggtg
     8581 atgcacggcc tgaagatcag cgacgaggac cgtcgcaccc tggtcaagta cctggccgac
     8641 aagcagggcc tggcgcccag cgagaccgac ggcgtgcgct acgccatgga gcgtcggctg
     8701 aacaccgtcg agcagttcga cgatcacctc agccagatgt gcggccgctg ccactccggt
     8761 gcccgtgtcg ccctgcagcg gcgcccggcg aaggagtggg agcacctggt caacttccac
     8821 ctcggccagt ggccgtccct cgaataccag gcccagtccc gcgaccgcga ctggctggac
     8881 atcgccctca agcagaccgt gcccgacctg gccaagcgct tcccgctgga cagccaggcc
     8941 tggaccgact ggcagaaggc ccggcccaag gccgacgtgc tgccgggcca gtggagcttc
     9001 agcggccaca tgctcgccaa gggtgatgtg cgcggcgtga tgaccgtgac cgccgatggt
     9061 gccgacacct tcaaggtgga cgtgaagggc cagtacgccg acggttcgcc gttcaccggc
     9121 agcggctcgg cgatcctcta caacggctac gaatggcgcg gcaacgtgaa ggtgggcgac
     9181 accaccctgc gccaggtctt cgccgccctc gacggtcaga tgaccggccg catgttcgag
     9241 agcgagcacg acgagcgtgg cctcgacttc agcgccgcga agcagggcca ggcccggctc
     9301 ctggcggtgc agccggcgca ggtcaaggcc ggcagcgaaa ccgagctgac cctggtgggc
     9361 agcggcctct cgggtgcgcc gcaactgggg gccggactgg aggtggtgaa ggtgctggac
     9421 agcaccccgg accatgtgcg ggtgaaggtg aaggcggccg ccgatgccgc ccccggcctg
     9481 cgtgaggtgt ccatcggtgc gctcaagggc gtgaccctgg cggtctacaa ggacatcgcc
     9541 gaggtcaagg tggtgcccgc gttctccatc gcccgcatcg gcgagaacgg cggctccacg
     9601 cccaaggtcc agggccgctt cgaggccgag gcctggggca ccgacgccgc cggcaaggcc
     9661 taccgcatcg gctacctgcc ggcgaaatgg tcggtggaac cgttcgatga gcgggccaag
     9721 gaagacgagg acgtgaagtt cgccggggtg atgcagaagg atggcgtctt cgtgcccggc
     9781 ggtgccggcc ccaacccgga acgcaagatg atgaccaaca acgccggcaa cctgaaggtg
     9841 atcgccgaac tggaggaggg cgggcagaag ggcgaaggcc acctgatcgt cactgtccag
     9901 cgctggaaca acccgccatt gccctgagtg ggaaggaccg ggcagggcgg ttgccccgcc
     9961 cggattcgaa acgaatcggg acgaattcca ggaggtcgcc atgggcgcaa tcttgaatct
    10021 ggtcgaacgc aacctgcacg aggtgcaggt caacaccgac cgcatgctgt tccacatccc
    10081 cagcagctcg ctgttcgcca ccgacgcgct gaccgggggc atcatcgacg ccctgcgcca
    10141 gcagggatgc tcgcccgagg agttggtgca acgcctgggc gggcgcttcg cgggggccga
    10201 gatcgacgag accctgcgcg agctgatcgc gctggaagtg gtgagcgacg gctcgccgct
    10261 gacgccggag atcggcctga agaaggtcga ccgcaccgcc ctcaacaccg tggtgctgaa
    10321 cgtcaacacc ggctgcaacc tgagctgcac ctactgctac aaggaagacc tcgacaagcc
    10381 ctcggccggc aagaagatgg ccgtggaaac cgccgaggcc tcggtggaga tgctgctgcg
    10441 cgagtccccc gacgaggccc gctacagcgt ggtgttcttc ggtggtgagc cgctctccaa
    10501 ccgcccgctg atcgagcaca tggtgggcta ctgcgagcgt cgcttcgccg ctgcgggcaa
    10561 gcaggtggag ttcgtcatga ccaccaacgc cacgctgctc accgaggaga tcgtcgactg
    10621 gctgaatgcc caccgcttcg ggctgtccat cagcatcgac gggccgaaga cggtgcacga
    10681 ccgcaaccgc atcaccgtag gcgggcaggg cacctacgac gtggtccggc gcaaggtgga
    10741 gatgctgctg tcgcgctaca ccagccgccc ggtgggcgcg cgggtgacgc tgaccaccgg
    10801 cgtcaccgac gtggaaacca tctgggacca cctgttcaac gaactgggct tcgccgaggt
    10861 ggggttcgcc ccggtcacct ccggcgacat cagcagcttc aacctaacgg cggacgagct
    10921 ggtgcaggtg ttcgccaaca tgaaggccct gggccggcgc tacctggagg cggcgctgga
    10981 gaaccgcaac atcggcttct ccaacctgca ccagctgatt accgacatcc acgagggtca
    11041 gaagaaggcg ctgccctgcg gggccgggct gaagatgctg gcggtggacc acaagggcga
    11101 gctgaacctc tgccaccgct tcaccggctc cagcctgccg accttcggca acgtgcacgg
    11161 cgcggtgaag caggccgagc tcaacgactt cctctcccag cgcctggacc gcaccggcac
    11221 cggctgcgac agctgccgca tccgcaacct ctgttccggc ggctgctacc acgagagcta
    11281 cgcccgctac ggcgatccca cgcacccgac ctatcactac tgcgaactga tgcgcgactg
    11341 ggtggacttc ggcatcgagg tctacagccg catcctggcc ggcaacccgg ccttcatcag
    11401 ccgcaccatc actccgcgga aggcgcactg acatgaaaca cctcaagccg ctgaaccaga
    11461 aagcgcacct gctcgaacag gccgcagccg aagaccgcct ggaagaagtc gttgccatga
    11521 gtgccgtcgc tggctgtacg gcgaccaccg acccgggctg ggaagtggat gccttcgggg
    11581 gcgtcagctc cctgtgccag cccatggagg ccgaccttta cggctgctcc gacccctgct
    11641 ggtggccggc ccaggtgccg gacatgatga ccacctacca ggactggaac gccagcgcgc
    11701 aggactcctc gcaggactgg cgcaacctcg gcaccgtctt ccccaaagac aaatgaccgg
    11761 ccacccgaac acgagggata acccgatgaa gctcaatgcg ttcgccagcc tggccgttgc
    11821 cgccgggctc gccctgggtg gccaggccct ggccgccgac aacgccggcc tggcactcaa
    11881 ggccggccag gaatacatga tcgccaccaa ctacccgaac aacctgcacg tgctcgacct
    11941 ggccagcgac agcctctaca agacatgccg cctgcccgac gccttcggac cgggcaccgc
    12001 catggtgtcg ccggatcgca agaccgccta cctgctcaac aaccacttcg gcgacctcta
    12061 cggcatcgac ctcgacagct gccgcgcggt gttccacgcc aagctttcgc gcaagccgga
    12121 cgagaaggcc cgctccatgt tcgccttcgc cctcagtccg gacggcaagg agctgtacag
    12181 cgtggtcaac ccgacccgca tggccagcga ccactacgag gtccagcagc cgcgcctgga
    12241 ggtgttcgac accgccgccg gcctggacgc ccagcccgtg cgcagcttcc cggtgccgcg
    12301 ccagctgtac atcatgcgcg ccgccgacga cggcaccctg tatatcgccg ggcccgacat
    12361 ctacaagatg gacgtgaaga ccggccacta cgaagtcgcc gtgcccggtc gcaattggaa
    12421 gcgccccaac tacggcccgc cggacgtgct gtacttctgg ccgcaccaga ccccgctgca
    12481 cgagttctcg atgctctaca ccaccaccag gttcaaggac gagaagcagg acccggccac
    12541 cgccgacttc gtctacggct acgtgagcat cgacctgaag accggcaagc ccaccgtgga
    12601 ggacttcgcg ccgctgaccg agctgtactt caccggcctg cgttcgccga aggacccgaa
    12661 ccagatgttc ggcgtgctca accgcctggc caagtacgac atcaagcagc agaagctgat
    12721 caaggccgcc aacctggacc actcctacta ctgcattgcc ttcaacaccc agggcagcaa
    12781 gctctacctg gccggcacct tcaacgacat cgccgtcttc gatccggaca gcctggagaa
    12841 ggtgaagaac atcaagctgc cgggcggtga catggccatc accaccaccc aggtattcgt
    12901 gcgctaggcc ggtgactccc ccgtggcccg ggcttgtgcc cgggagcggg gcgggtctgc
    12961 cgtaggcgtt cgcacgcgtc attccacgcc atctacgacc aatgggtcac tggacagaac
    13021 aaaacccttt acccagattg acgtttacgt aaaggtaatc ggcctccctg cccgaatcgg
    13081 aggccactcg gaacgacccg atcccaccac aacgacaaga agggacagcc atgcatcaac
    13141 cgagctatac ccgggggcgc caggacaagc ccctgctcgc catgaccatc ggcgcggcat
    13201 tcgacgccac ggtcgcccga ttccccgaac gcgaagccct ggtggtgcgc caccaggggc
    13261 tgcgctacag ctggcgcagc ctggccgagg cggtggaggc ccatgcccgc gcgctgatgg
    13321 ccttgggtat ccagagcggc gaccggctcg gcatctgggc gcccaactgc gccgagtggt
    13381 gcatcaccca gttcgccagc gccaaggtcg gcgccatcct cgtcaacatc aacccggcct
    13441 atcgcagcag cgagctggag tacgccctgc gccagtccgg ctgccgctgg gtgatctgcg
    13501 ccgacgcctt caagacctcc gactaccacg ccatgttgca gggcttggtg ccggagctgg
    13561 ccagcgcgcc catcggccag ctcgccagcg aggcgctgcc cgaactgcgc ggggtgatca
    13621 gcctggccgc cgaaccgccg gccggcttcc tcgcctgggc cgacctgcag cagcgggcag
    13681 gggaggccac cccggccgag ctggccgagc gccaggccag cctgcagttc gacgacccca
    13741 tcaacatcca gtacacctcc ggcaccaccg gcttccccaa gggcgccacc ctcagccact
    13801 acaacatcct caacaacggc tacatggtcg gcgagagcct ggggctaacc gagcacgacc
    13861 gcctggtgat cccggtgccg ctgtaccact gcttcggcat ggtcatgggc aacctgggct
    13921 gcgtgaccca cggcgccacc atgatctacc ccggcgacgc cttcgacccg ctcaccgccc
    13981 tgcgcgccgt ggcggaggag aaggccaccg tactgtacgg cgtgccgacc atgttcatcg
    14041 ccgagctgga ccacccgcag cggcatgaat tcgacctctc cagcctgcgc accggcatca
    14101 tggccggcgc gacctgcccc atcgaggtga tgcgccgggt catcggcgaa atgcacatga
    14161 gcgaggtgca gatcgcctac ggcatgaccg agaccagccc ggtgtccctg cagaccggcc
    14221 cggatgacgg gctggagctg cgcgtcacca ccgtcggccg cacccagccg cagctggaga
    14281 gcaagatcgt cgatgccgag ggccgcatcg tgccgcgcgg caccatcggc gagctgtgca
    14341 cccggggcta cagcgtgatg ctcggctact ggaacaaccc ccaggccacc gccgacgcca
    14401 tcgacccggg ccgctggatg cacaccggcg acctcgcggc catggacgac gacggctacg
    14461 tgcgcatcgt cgggcgcagc aaggacatga tcatccgcgg cggcgagaac atttaccccc
    14521 gcgagctgga ggagttcttc ttcacccacc cggccgtggc cgacgtgcag gtgatcggca
    14581 ttccctgcag caagtacggc gaggagatcg tcgcctggat caagttccac cccggccaca
    14641 gcgccggcga ggaggagctg aagacctggg ccaaggcccg catcgcgtac ttcaaggtgc
    14701 ctcggcactt ccgtttcgtg gacgagttcc ccatgacggt gaccggcaag atccagaagt
    14761 tccgcatgcg cgagatcagc atcgaggagc tgacgccgcc ccgggacggc aaggtgacgg
    14821 cgatccgcta gcgccccagg gagccgcgtc ttgcgcggct ccttatcccg ccttccatct
    14881 cctacactgg gcgcccgtaa tcgccatgac ccccggaacg ccatgacagg aacgtcagcc
    14941 gagaaaggca ccatctccgt ccgcctcgtc gacgaagcac tgcaggtgct tcgccagcag
    15001 gggggcgacg tcgccgcgct gctggagcag gccggcattc ccgccgagca gatggcccgg
    15061 ccctacggtc gggtcgcctc caggcagtac gcccagctgt ggctgctgat cgcccgggtg
    15121 atggatgacg agttcttcgg catggacagc cgccggctca agtccggcag cttcgcccac
    15181 atgagccgga ccgccctgca ggccgccacc ctgggggacg cgctgcaggc cagcctgacc
    15241 ttcctcgccc tggtgctgga tgacctgcag ccccgcctgg cgcggcgcgg cagcctggcg
    15301 gagatcgtcc tcgacgacag cggcgcgccg cctcgggcct tcgcctgctt caccctgttc
    15361 ctcatggtcc acggcctgct ctgctggctg gccggtcggc gcctgccgat cctcggcatc
    15421 gagctacggg ggccgcagcc ggcctacatc gaggactacc gggtgatgtt caccccgcac
    15481 ctccgcttcg gccgcgacac cacgcgcctg gtgttcaacg ccgactgcct ggcccagccg
    15541 gtgcgccgca acgaggcgga cctgcggcgc ttcctcgccg gtgcaccggc caacatcctg
    15601 gtgcgctacc gcgaccccca gagcctggcc gcccgcatca agacctacct gcgcagcctg
    15661 cgccccgagc gctggccgga cctggaggcg ctctccgggc acttctacat ggcgccctcc
    15721 accctgcggc gcaagctcac ccaggagggg cagtcctacc aggcgctgaa ggaccaggtg
    15781 cgccgcgacc tggcggtcgc ccggctggac gcgggcgagg tcaacttcac cgagctggcc
    15841 ttcgagctcg gcttcgccga cgccagcgcc ttctacaagg cgttccgcaa gtggaccggt
    15901 tccacccccg ggcagtaccg ggcgctggtg caccccgagg cgggctgagc cccctcactt
    15961 ggcgaacagc tggccgatgt cccggaacgc cttgaactcc agcgcgttgc cgcacgggtc
    16021 gagcaggaac agcgtcgcct gctcgcccac ctggcccttg aagcgcacat agggctcgat
    16081 cacgaagcgc gtgccgaggc gttgcagccg ctcggccagg gcctcccagt cctcccaggc
    16141 gagcaccacg ccgaagtgcg gcaccggcac gtcgtggccg tccaccgggt tggtgtgggc
    16201 ggcgagctgg ctggtggtcg gcgggtgctc gtggatcacc agctggtgac cgaagaagtc
    16261 gaagtccacc cactgcgcgc tggagcggcc ttcggcgagg ccgaacacct cgccatagaa
    16321 acgccgcgcg gcgggcaggt cgtgaacggg gattgcgagg tggaaggggg cgagttgcat
    16381 gctgtgctcc tgttttgtgt gcccatttta gatgtggaga tttcgatgca aagccaggat
    16441 tatttgtgcc gagcacgaac gttttcgatc aatgaggcac cccatgctgc gagagatccg
    16501 caccttcgtc gccgtggccc gccatggcac cttcgccgct gccggcatgc acatcggcct
    16561 cacccagtcc gccgtcagcg cgcagatccg caacctggaa gaagcgctgg gcgtgcgcct
    16621 gttcgaccgc accggccgcc aggcgctgct caacgcggcc ggtgagcggg cgctgcccct
    16681 ggcacgggag atgctcgacc tgttcgcccg catggcggcc acggacgagg cgggcgccca
    16741 tgccggggag ctgcgcatcg gtgccatcgc caccgcccag accgggctgc tggcggacgc
    16801 gctgctgcgc ctgcgggagc gcgccccggc ggtggagccg aagctggtgc ccggcgtttc
    16861 gctgaacctg ctgagccagg tggatgccgg cgacctggac ctggccatcc tcatccgccc
    16921 gccattcgaa ctgcccaagg aactgcatgc cgaggtgctg cgggaggaag ccttcgtgct
    16981 ggtggtgccg cgcggcctgg agggcgacga cccgctgcgc ctgctggccg agcagccgct
    17041 ggtgcgctat gaccgcacct ccttcggcgg gcgcctggtc acccgcttcc tgcgccagca
    17101 gcggctggac gtgaaggtgg cgctggaact ggacgagctg gacgccatcg tacgcatggt
    17161 cgaggccggc ctcggcatcg cgctgatccc cgaagcgggc ctgtggctgg aacgcgacgc
    17221 cgccatccgc gtggtccgcc tcggcccgct gaccttccac cggcagatca tcctgctcac
    17281 gcgccacgcc cagcgccgcc agccgctgca gcgtctgttc gcagcctgcc tggcggggga
    17341 ggacgccaaa tagccgggcc ctagaccgcc cgcaggccgg cttcggcggg gggctggccg
    17401 gatggtgggg ctttgagcag caggcggatg cggttggcca gggcgtcgat ggcgtagggc
    17461 ttggccatga cctccatccc cgggggcagg ggttcgttgc cgaacggggc gttctgggcg
    17521 tagccggtga tgaacagcac cttcaggtcc gggcgttgca ggcgggcgcg gcgggccagt
    17581 tccaggccgt tcaggccccc cggcaggccg acgtcggcca gcagcaggtc gaccgctcgc
    17641 tcgccggcaa gcagggcgag ggccccgggg ccgtccgcgg cttcgagcat ctggtagccg
    17701 aggtcttcca gcacttcgcg catcagctgg cgcaggggcg cttcgtcgtc caccaccagt
    17761 acggtggtgc actgctcggc gcgggggatt tcaaccgggc ggggtgttgg cgcgggctct
    17821 gcctcgccgt ggtggcgggg caggtagagg ctgaggctgg tgccctggcc gagggtggag
    17881 gcgatgcgca cctgcccgcc ggattgccgg gcgaagccgt acaccatcga gagcccgagg
    17941 ccggtgccct ggcccaccgg cttggtggtg aagaagggtt cgaaggctcg gctgatgacg
    18001 tcctcgctca tgccgctgcc ggtgtcgctg accatcagca ccaggtagtc ccccggttcc
    18061 agcccgcgct cgccggcagc ctgggcgccg agcacgacat tattgctgcc gatgcacagg
    18121 cggccgccgt tgggcatggc gtcgcgggcg ttgatacaga tgttgagcag ggcgctttcc
    18181 agctggttcg ggtccaccag caccgtccac aggtccgggc cgtcgacgca ctccacctcg
    18241 atgttcgggc ccatggtccg gctgatcagt tcgtgcagcg tcgcgaccag ttggttgacg
    18301 tcggtggggc gcggatcgag ggcctggcgg cgggagaagg cgagcaggcg gtgggtgagg
    18361 gtggcggcgc gttcggcggc gctgcgggcg atgtcgatgt agcggttaag gtcctcggtg
    18421 cgcccctggg cgatgcgcag gcgcagcagc tccaggctgc cgctgatgcc ggcgaggagg
    18481 ttgttgaagt catgggcgag gccgccggtg agctggccga cggcctccat cttctggctc
    18541 tggcgcagtt gctcctcggc ctggcgcagg gcgtcggcgc gggcgcgttc ctcggtggtg
    18601 tcgcggccga tggcgctgat gaagccgtcg cccgaggagg aggaccagtt gatccagcgg
    18661 tagctgccat cgcgatggcg catgcggctg gcgtagtccc gcaggggctc gccctggatc
    18721 aggctgtgga tggcggccca ggcgtcggcg aggtcgtcgg ggtgcaccag gtccaggcag
    18781 ttgctgccca ccagctcggc ttcgctccag ccgaggatgt tctgcgtggc ggggttggcg
    18841 gcggtgatca ccaggtcctg gcgcgacacc agcatgatgt ccggcgagag gttccacagg
    18901 cggttgcggt cgcgggtgcg ctcggccacc tggcgctcca ggttgtgggt gagctggcgc
    18961 aactggcgct cggcggtgac ccgggaggtg gtctcgatta ccgtgtcgag catgcccagc
    19021 acccggccgt cggcgtcccg cagcgggctg tagcagaagg tgaaatagct catctccggt
    19081 cgcccgtggc ggtccagctc cacggggaaa tcctcgatga aggtggcctg gccctggtag
    19141 gcccgctcgg cgatggggcc gatgctgtcc caggcttctc gccagatgtc gtcgaagggc
    19201 cggccgagtg gcgcgtgctt gttgccgagg atgggcacga aaccgtcgtt gtagatggag
    19261 atgcgctgcg gcccccatac caggcagcag gggaagtgcg aggacaggat ggtgtcgacg
    19321 ctgatgcgca gcgcctcggg ccagtgctcg atcgggccta gcggggtgcg ggaccagtcg
    19381 tgctggcgca cctgctggct catcggcccg ggggcggcgg ggaagggggt agcgtccatg
    19441 tcaggattcc gaggggcagc agcgaggatg gccgggtcag aggagttgac cacgaagcgg
    19501 ccggacaatt cgattccgcg atgcctgttt gccgtggtgg tgacggcgag caggcgcgag
    19561 gacctagcgc tgctcggcct gctcgatgag ttcgagcacg tcggccaggg tggcgtcgag
    19621 gtgctcgccg gccttgtagg cgcgcagcac ggcctcgtca ccctcgcgga cgaggcgcgg
    19681 ccgttcgatg aacagcccgg cgggctcgaa ggcctcgtcc agcaccacca ccaggggaat
    19741 ggcgatgcgc tccaggccca ggcgggtctt caggtcgtct tcggcgcggc ccttggtgat
    19801 caccgcgagg tcgatgcgcg gctggcggcg gcacaggtcg tccagcacgg tgacgttgat
    19861 ctggcagtcc gggcaccaca tctcgcccac caccagcagg tggtagcggc gttcgatctg
    19921 ctcgatgcgc tgcagcagtg gggcggccgg tccctggtct tccaggcgct gggcgatggc
    19981 ggcggctgcg gcggtctcgg ccggtaggcc gctgccgacg aactcggtgt aggactggcc
    20041 gatgtcgaac agctcgcgat aggtcgccat ggggatgctc cgttgaaagt gaggcggcat
    20101 cccagcagaa aagcccaccc ggggcaactg cgcctcaccc cggcgacagg tagccgagca
    20161 actgccgggc gtgggagccg aggccatcgg tgccacggat gcacaggcgc agctcgcggg
    20221 tggcccaggt gtcctccagg gtgacgatgg ccaccggcag ctcctgggtc aggcggtggg
    20281 cggcggcctc cggaagcatg gcgatgccgg cgccctgggc caccagctgg gcgatggcgt
    20341 cgaagctcgg tgcgcggacc cgcaccatca gcggcaggcc gttctgccgg gccatttcct
    20401 cgacgaagcg ctgcatggag cgctccgccg gcaggcacac gaaggggtag cccaaggtgt
    20461 cgcgcaggtg gacgctgcgc agcggcgcga gggcgtggcc agcaggcacc agcatcacca
    20521 ggcggtcgtc gcggaagggc agggagatca gcccgccggt gggcaggttg ccgtcgtaca
    20581 cgccgatgtc gatgtcgccg gcctgcacac cccgcagcac gtcgcggctg gtctgctcgg
    20641 tgagctgcag gtccacctcg gggtagtccg ccaggaaggg gccgagggcg cccggcagga
    20701 aggagctgtt ggccacggtg gtagcggcca ggtggacgac gacgcgctgc tggccggcca
    20761 gctcctccag cagcaccttg agcccctggg cttcgttgag cagcgcgtgg cagcgctcca
    20821 gcaccaggcg gccggacggg gtgggcgtca tgccgtcggc gcggcgggtg aagagggtga
    20881 tgccgcagcg ggattcgaac tggcgcaacc gggtgctggc cgcagagacc gccacgggga
    20941 aggtggccgc cgccttgctc aggctgccgg tggcggcgat ggcgctcagc aggcgcaggt
    21001 cggacaggtc gaagtgcatg gcgttctgat ttccataagg ggtggttctg gaaaaaccga
    21061 ttctagccct ctcgcgttct gtccagaata aggctctacc tgctgatggc ctgcctcatg
    21121 aacgctctgt tttccctgta ccagcgcggc ctgcgcaacg gcagcctgtt cgccgtgctc
    21181 tcggcggcgg gcttcagcct caaggcgatc ttcgtcaagc tgtcctatgc cgccgccccg
    21241 gtggatgcga tcaccgtgct ggcgctgcgc atggggctgg cactgccgct gttcgcctgg
    21301 ctgctgtggc tgagccgcgg gacgggcgag gcgcgcctgt cgcccgccga tggggggcgc
    21361 atcctgctgc tggggctggt gggctactac ctctccagcc tgttcgattt ctatgggctg
    21421 gagtccatca g
//
