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Overview
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### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AP022642.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 918,213 | 927,794 | pseudopyronine A / pseudopyronine B | Other:Fatty acid | 12%
Region 2 | redox-cofactor | 1,802,454 | 1,824,616 | lankacidin C | NRP + Polyketide | 13%
Region 3 | NAGGN | 2,647,999 | 2,662,791 |
Region 4 | ranthipeptide | 2,741,160 | 2,762,590 | pyoverdin | NRP | 4%
Region 5 | NRPS | 2,832,413 | 2,884,721 | pyoverdin | NRP | 4%
Region 6 | T3PKS,CDPS | 3,063,489 | 3,122,628 | 2,4-diacetylphloroglucinol | Polyketide | 100%
Region 7 | RiPP-like | 3,188,773 | 3,199,585 | methanobactin | RiPP | 50%
Region 8 | NRPS | 3,375,205 | 3,438,853 | pyoverdin | NRP | 9%
Region 9 | butyrolactone | 4,594,247 | 4,607,603 |
Region 10 | arylpolyene | 5,607,940 | 5,651,524 | APE Vf | Other | 45%

NZ_AP022642.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 918,213 - 927,794 nt. (total: 9,582 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000928.1 |  | 0.15 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.15 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0000506.1 |  | 0.10 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0001285.1 |  | 0.09 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001686.1 |  | 0.09 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001727.1 |  | 0.09 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000559.1 |  | 0.09 | RiPP | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001789.1 |  | 0.09 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.09 | RiPP | nisin U | Streptococcus uberis
BGC0000668.1 |  | 0.08 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000928.1 |  | 0.45 | Other | T3 toxin | Cylindrospermopsis raciborskii T3
BGC0000188.1 |  | 0.45 | Alkaloid | saxitoxin, neosaxitoxin, decarbamoylsaxitoxin, gonyautoxin 3, gonyautoxin 2 | Cylindrospermopsis raciborskii T3
BGC0000506.1 |  | 0.34 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0001285.1 |  | 0.34 | Other (Fatty acid) | pseudopyronine A, pseudopyronine B | Pseudomonas putida
BGC0001686.1 |  | 0.34 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001727.1 |  | 0.33 | RiPP | paenilan | Paenibacillus polymyxa E681
BGC0000559.1 |  | 0.33 | RiPP | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001789.1 |  | 0.32 | RiPP | suicin 90-1330 | Streptococcus suis
BGC0000537.1 |  | 0.32 | RiPP | nisin U | Streptococcus uberis
BGC0000668.1 |  | 0.31 | Terpene, Alkaloid | 12-epi-hapalindole C isonitrile, 12-epi-hapalindole E, 12-epi-fischerindole U isonitrile, fischerindole L, 12-epi-fischerindole I isonitrile, welwitindolinone A isonitrile, welwitindolinone B isothiocyanate, welwitindolinone C isothiocyanate, N-methylwelwitindolinone C isothiocyanate, N-methylwelwitinsolinone C isonitrile, 3-epi-welwitindolinone B isothiocyanate, 3-(Z-2'-isocyanoethenyl)-indole | Hapalosiphon welwitschii UTEX B 1830

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 2 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,802,454 - 1,824,616 nt. (total: 22,163 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.15 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.14 | Other | dehydrophos | Streptomyces luridus
BGC0000874.1 |  | 0.14 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0000665.1 |  | 0.13 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0000548.1 |  | 0.13 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000906.1 |  | 0.13 | Other | heme D1 | Heliophilum fasciatum
BGC0000452.1 |  | 0.12 | NRP | tyrocidine | Brevibacillus brevis NBRC 100599
BGC0000666.1 |  | 0.11 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000343.1 |  | 0.10 | NRP | enterobactin | Pseudomonas sp. J465

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.45 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000703.1 |  | 0.44 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.43 | Other | dehydrophos | Streptomyces luridus
BGC0000874.1 |  | 0.43 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0000665.1 |  | 0.42 | Terpene, Alkaloid | xiamycin | Streptomyces sp. HKI0576
BGC0000548.1 |  | 0.42 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000906.1 |  | 0.41 | Other | heme D1 | Heliophilum fasciatum
BGC0000452.1 |  | 0.39 | NRP | tyrocidine | Brevibacillus brevis NBRC 100599
BGC0000666.1 |  | 0.37 | Terpene | xiamycin A | Streptomyces sp. SCSIO 02999
BGC0000343.1 |  | 0.37 | NRP | enterobactin | Pseudomonas sp. J465

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 3 - NAGGN
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,647,999 - 2,662,791 nt. (total: 14,793 nt) Show pHMM detection rules used
NAGGN: ((TIGR03104 or cds(GATase_7 and Asn_synthase)) and TIGR03103 and (TIGR03106 or Peptidase_M42))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAGGN | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000846.1 |  | 0.26 | Other | tabtoxin | Pseudomonas syringae
BGC0000885.1 |  | 0.24 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000937.1 |  | 0.20 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001739.1 |  | 0.17 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000781.1 |  | 0.14 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001374.1 |  | 0.14 | Other | thienodolin | Streptomyces albogriseolus
BGC0000892.1 |  | 0.13 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0001395.1 |  | 0.12 | Other | teichomycin | Actinoplanes teichomyceticus
BGC0000796.1 |  | 0.12 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001007.1 |  | 0.12 | Polyketide, NRP | lymphostin, neolymphostinol B, lymphostinol, neolymphostin b | Salinispora arenicola CNS-205

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000846.1 |  | 0.59 | Other | tabtoxin | Pseudomonas syringae
BGC0000885.1 |  | 0.57 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000937.1 |  | 0.52 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001739.1 |  | 0.48 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000781.1 |  | 0.43 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001374.1 |  | 0.43 | Other | thienodolin | Streptomyces albogriseolus
BGC0000892.1 |  | 0.42 | Other | caryoynencin | Burkholderia gladioli BSR3
BGC0001395.1 |  | 0.40 | Other | teichomycin | Actinoplanes teichomyceticus
BGC0000796.1 |  | 0.40 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001007.1 |  | 0.39 | Polyketide, NRP | lymphostin, neolymphostinol B, lymphostinol, neolymphostin b | Salinispora arenicola CNS-205

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 4 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,741,160 - 2,762,590 nt. (total: 21,431 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000842.1 |  | 0.20 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0001935.1 |  | 0.19 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001487.1 |  | 0.19 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001897.1 |  | 0.18 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000649.1 |  | 0.18 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000807.1 |  | 0.18 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0000706.1 |  | 0.16 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.15 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0001765.1 |  | 0.15 | Saccharide | salecan | Agrobacterium tumefaciens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000842.1 |  | 0.52 | Other (Non-NRP beta-lactam) | carbapenem MM4550 | Streptomyces argenteolus
BGC0001935.1 |  | 0.51 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001487.1 |  | 0.51 | Other | 3,7-dihydroxytropolone | Streptomyces cyaneofuscatus
BGC0001897.1 |  | 0.50 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000649.1 |  | 0.49 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000807.1 |  | 0.49 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0000706.1 |  | 0.47 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001120.1 |  | 0.46 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.45 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0001765.1 |  | 0.45 | Saccharide | salecan | Agrobacterium tumefaciens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,832,413 - 2,884,721 nt. (total: 52,309 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001479.1 |  | 0.29 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001671.1 |  | 0.28 | NRP | monobactam | Agrobacterium tumefaciens
BGC0001833.1 |  | 0.28 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001825.1 |  | 0.27 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001132.1 |  | 0.26 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000313.1 |  | 0.26 | NRP | beauvericin | Beauveria bassiana
BGC0001844.1 |  | 0.26 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000342.1 |  | 0.26 | NRP | enniatin | Fusarium equiseti
BGC0001873.1 |  | 0.26 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338
BGC0001128.1 |  | 0.25 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001479.1 |  | 0.63 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001671.1 |  | 0.62 | NRP | monobactam | Agrobacterium tumefaciens
BGC0001833.1 |  | 0.62 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001825.1 |  | 0.60 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001132.1 |  | 0.60 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000313.1 |  | 0.60 | NRP | beauvericin | Beauveria bassiana
BGC0001844.1 |  | 0.60 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000342.1 |  | 0.60 | NRP | enniatin | Fusarium equiseti
BGC0001873.1 |  | 0.59 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338
BGC0001128.1 |  | 0.59 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 2832412 - 2884721:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (glu - D-X - X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_2572: pk - glu - X - X
  Search NORINE for peptide: strict or relaxed
  CAL_domain (40..479): pk
  minowa: NH2
  Prediction, score:
    NH2: 151.6
    Acetyl-CoA: 53.8
    AHBA: 14.2
    fatty_acid: 13.8
    shikimic_acid: -2.4
  AMP-binding (1130..1527): glu
  NRPSPredictor2: glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      glu, gln
    Single AA prediction:
      glu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFGRINK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2189..2593): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAegiGAVMK
    Nearest Stachelhaus code:
      phe
    Stachelhaus code match:
      70% (weak)
  AMP-binding (3719..4125): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DiWeLtadDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      50% (weak)

NZ_AP022642.1 - Region 6 - CDPS,T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,063,489 - 3,122,628 nt. (total: 59,140 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)
CDPS: (CDPS or cycdipepsynth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | CDPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000280.1 |  |  | 0.61 | Polyketide | 2,4-diacetylphloroglucinol | Pseudomonas fluorescens
BGC0000281.1 |  |  | 0.60 | Polyketide | 2,4-diacetylphloroglucinol | Pseudomonas fluorescens
BGC0000286.1 |  |  | 0.27 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0001077.1 |  |  | 0.27 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0001377.1 |  |  | 0.25 | Polyketide | uncialamycin | Streptomyces uncialis
BGC0001815.1 |  |  | 0.25 | Polyketide | uncialamycin | Streptomyces uncialis
BGC0000902.1 |  |  | 0.24 | Other | flaviolin | Saccharopolyspora erythraea NRRL 2338
BGC0000285.1 |  |  | 0.24 | Polyketide, Saccharide | flaviolin rhamnoside, 3,3'-diflaviolin, flaviolin | Saccharopolyspora erythraea
BGC0001310.1 |  |  | 0.24 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0001804.1 |  |  | 0.21 | Polyketide | tiancimycin | Streptomyces sp. CB03234

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000280.1 |  | 0.85 | Polyketide | 2,4-diacetylphloroglucinol | Pseudomonas fluorescens
BGC0000281.1 |  | 0.84 | Polyketide | 2,4-diacetylphloroglucinol | Pseudomonas fluorescens
BGC0000286.1 |  | 0.61 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0001077.1 |  | 0.60 | Terpene, Polyketide | alkyl-O-dihydrogeranyl-methoxyhydroquinones | Actinoplanes missouriensis 431
BGC0000902.1 |  | 0.57 | Other | flaviolin | Saccharopolyspora erythraea NRRL 2338
BGC0000285.1 |  | 0.57 | Polyketide, Saccharide | flaviolin rhamnoside, 3,3'-diflaviolin, flaviolin | Saccharopolyspora erythraea
BGC0001310.1 |  | 0.57 | Terpene | naringenin | Streptomyces clavuligerus ATCC 27064
BGC0000679.1 |  | 0.54 | Terpene | diazepinomicin | Micromonospora sp. M42
BGC0002000.1 |  | 0.54 | Polyketide | setomimycin | Streptomyces aurantiacus JA 4570
BGC0000225.1 |  | 0.53 | Polyketide | frenolicin B | Streptomyces roseofulvus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 7 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,188,773 - 3,199,585 nt. (total: 10,813 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002004.1 |  | 0.23 | RiPP | methanobactin | Methylosinus trichosporium OB3b

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002004.1 |  | 0.56 | RiPP | methanobactin | Methylosinus trichosporium OB3b

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 8 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,375,205 - 3,438,853 nt. (total: 63,649 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001050.1 |  | 0.39 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0000349.1 |  | 0.35 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001767.1 |  | 0.34 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000457.1 |  | 0.33 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001833.1 |  | 0.32 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000389.1 |  | 0.32 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.31 | NRP | sevadicin | Paenibacillus larvae
BGC0001135.1 |  | 0.31 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000438.1 |  | 0.31 | NRP | syringopeptin 25A | Pseudomonas syringae pv. syringae
BGC0001128.1 |  | 0.30 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001050.1 |  | 0.71 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0000349.1 |  | 0.68 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0001767.1 |  | 0.67 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000457.1 |  | 0.66 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001833.1 |  | 0.65 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0000389.1 |  | 0.65 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.64 | NRP | sevadicin | Paenibacillus larvae
BGC0001135.1 |  | 0.64 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000438.1 |  | 0.64 | NRP | syringopeptin 25A | Pseudomonas syringae pv. syringae
BGC0001128.1 |  | 0.64 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 10, location 3375204 - 3438853:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X) + (D-asn - X) + (D-ser - X - D-X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_3044: ser - X - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (515..913): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2022..2431): X
  NRPSPredictor2: glu, gln
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      glu, gln
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgeDhGtVtK
    Nearest Stachelhaus code:
      gln
    Stachelhaus code match:
      50% (weak)
  AMP-binding (3099..3499): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      orn, lys, arg
    Small clusters prediction:
      N/A
    Single AA prediction:
      lys
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGeccGgVtK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      50% (weak)
ctg1_3045: asn - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (499..900): asn
  NRPSPredictor2: asn
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asp
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKIGhVGK
    Nearest Stachelhaus code:
      asn
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (2016..2422): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DiWeLtadDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      50% (weak)
ctg1_3046: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (523..934): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DGedhGtVVK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      60% (weak)

NZ_AP022642.1 - Region 9 - butyrolactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,594,247 - 4,607,603 nt. (total: 13,357 nt) Show pHMM detection rules used
butyrolactone: AfsA

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | butyrolactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001480.1 |  | 0.18 | Other | tundrenone | Methylobacter tundripaludum 21/22
BGC0000056.1 |  | 0.16 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001484.1 |  | 0.15 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365
BGC0000886.1 |  | 0.13 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0002009.1 |  | 0.13 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001160.1 |  | 0.13 | Polyketide | 1-nonadecene, (14Z)-1,14-nonadecadiene | Synechococcus sp. PCC 7002
BGC0001164.1 |  | 0.13 | Polyketide | 1-heptadecene | Cyanothece sp. PCC 7822
BGC0000044.1 |  | 0.12 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0001182.1 |  | 0.11 | NRP, Polyketide | chaetoglobosins | Chaetomium globosum CBS 148.51
BGC0001218.1 |  | 0.11 | NRP, Polyketide | fumosorinone | Cordyceps fumosorosea

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001480.1 |  | 0.50 | Other | tundrenone | Methylobacter tundripaludum 21/22
BGC0000056.1 |  | 0.46 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001484.1 |  | 0.46 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365
BGC0000886.1 |  | 0.42 | Other | allylmalonyl-CoA | Streptomyces tsukubensis
BGC0002009.1 |  | 0.42 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001160.1 |  | 0.41 | Polyketide | 1-nonadecene, (14Z)-1,14-nonadecadiene | Synechococcus sp. PCC 7002
BGC0001164.1 |  | 0.41 | Polyketide | 1-heptadecene | Cyanothece sp. PCC 7822
BGC0000044.1 |  | 0.41 | Polyketide | dawenol | Stigmatella aurantiaca DW4/3-1
BGC0001182.1 |  | 0.38 | NRP, Polyketide | chaetoglobosins | Chaetomium globosum CBS 148.51
BGC0001218.1 |  | 0.37 | NRP, Polyketide | fumosorinone | Cordyceps fumosorosea

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP022642.1 - Region 10 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 5,607,940 - 5,651,524 nt. (total: 43,585 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000836.1 |  | 0.27 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.25 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000234.1 |  | 0.23 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.22 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002008.1 |  | 0.22 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000272.1 |  | 0.21 | Polyketide | spore pigment | Streptomyces collinus
BGC0000261.1 |  | 0.21 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000194.1 |  | 0.20 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000246.1 |  | 0.19 | Polyketide | mithramycin | Streptomyces argillaceus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000836.1 |  | 0.61 | Other | APE Ec | Escherichia coli CFT073
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000234.1 |  | 0.56 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.55 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002008.1 |  | 0.55 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000272.1 |  | 0.54 | Polyketide | spore pigment | Streptomyces collinus
BGC0000261.1 |  | 0.53 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000194.1 |  | 0.52 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000246.1 |  | 0.51 | Polyketide | mithramycin | Streptomyces argillaceus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names