LOCUS       c00049_NZ_JAWO..       23464 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAWONS010000252.1 Clostridium boliviensis strain E-1 contig00010,
            whole genome shotgun sequence.
ACCESSION   c00049_NZ_JAWO..
VERSION     c00049_NZ_JAWO..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:22:44
            Original ID  :: NZ_JAWONS010000252.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 58209
            Orig. end    :: 81673
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23464
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[68209:71673]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13464
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..23464
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23464
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(1250..2071)
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 220.7; E-value:
                     3.8e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_56"
                     /transl_table=11
                     /translation="MYWKFRKTIPYVVLTLLAVIFALPLLWILLASFDVNASQAVKMPS
                     QWTMENYKTILLNQANQRAFGNGLLISLGQSVLVVLIAGFAAYPLSRYELRYKNIFLYT
                     ILFMTSLPITAVMVPVYKMFLTVGLYDKIGGLILFLTATSMPYGIWLMKNFMDNVPVEL
                     EEAAWVDGASAFGSLRKIIAPLMFPGICVVFIFTFSGSWGNFFVPYILLQTLDKFPASV
                     TLYQFFGQHGMVIYGQLAAYSAVYAVPSIVLYVLSQNYMSKGFNMAGAAKG"
     PFAM_domain     complement(1304..1831)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_56_0001"
                     /evalue="8.80E-16"
                     /label="ctg49_56"
                     /locus_tag="ctg49_56"
                     /protein_end="256"
                     /protein_start="80"
                     /score="58.3"
                     /tool="antismash"
                     /translation="LIAGFAAYPLSRYELRYKNIFLYTILFMTSLPITAVMVPVYKMFL
                     TVGLYDKIGGLILFLTATSMPYGIWLMKNFMDNVPVELEEAAWVDGASAFGSLRKIIAP
                     LMFPGICVVFIFTFSGSWGNFFVPYILLQTLDKFPASVTLYQFFGQHGMVIYGQLAAYS
                     AVYAVPSIVLYVL"
     CDS             complement(2085..2963)
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 219.6; E-value:
                     8.6e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_57"
                     /transl_table=11
                     /translation="MKKKQSGLLEEANKSVLLMPSVLLLLVFFVAPILLTVYYSFTNLA
                     LSGENARQLKFIGLSNYFTMFKDRTVRISIVNTLVFLLGSLIGQQVLGFIIALNMRNKN
                     RIFRGIVGPIFLAGWIMPEVVVALCCSTFFGDSGTLNQIFSFLRLPQVEFLFAVPMLTV
                     ILANIWHGTAFSMMNFQSALDGVPADIEEAARVDGAGPFQTMIRIILPCIKNTIATNTM
                     LNTLSTLGVFGLIYMMTGGGPGTKTLTLPIFMYRQAFISQQLGYGTAISMILLVIGIVL
                     SVFYTRIMRND"
     PFAM_domain     complement(2100..2693)
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_57_0002"
                     /evalue="1.40E-19"
                     /label="ctg49_57"
                     /locus_tag="ctg49_57"
                     /protein_end="288"
                     /protein_start="90"
                     /score="70.6"
                     /tool="antismash"
                     /translation="VLGFIIALNMRNKNRIFRGIVGPIFLAGWIMPEVVVALCCSTFFG
                     DSGTLNQIFSFLRLPQVEFLFAVPMLTVILANIWHGTAFSMMNFQSALDGVPADIEEAA
                     RVDGAGPFQTMIRIILPCIKNTIATNTMLNTLSTLGVFGLIYMMTGGGPGTKTLTLPIF
                     MYRQAFISQQLGYGTAISMILLVIGIVLSVFYTRI"
     CDS             complement(3042..4460)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 199.3; E-value:
                     2.1e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_58"
                     /transl_table=11
                     /translation="MKKMKRIQAAALASVMALSLTACQGAGSKPETQGGSTAAATQKET
                     EKPADKTTEAGKTKISITFRNDGSDVLKKWFEHAYETYEKKDSIELDIAPITASEGDYF
                     AKVALALQSADTAPDIVCEDTFQLPSDVAAGYLTDLSGYLKDYKEWNDGTFYGALVDGV
                     TYDDGSVYGIPYCTDTRGLWYNKDVFAAAGLDTNWQPKTWQDVLDTCKIIKEKCPDVVP
                     FWCNSGVATGEATSMQTYEMLLYGTGEQLLDNDKWIVKSDNILKSLNFISTIYKDGYGP
                     SLSKVLNGEAGNIASREYLPKGKLAITLDGYWMTGNYKETGAAPWPEYKDKLGIAAMPT
                     SEGQAPGSITMSGGWALSIPQLSDQKDAVMDFIKHCMSYDVYLDTIIAQGNIATRTDIA
                     KDASYSSQPFMETCTGFLSGAFYRPRNSQYTTVTTHIQTMVESVVSGTSPEDAMAQYKS
                     DVTNSVGAENVVEK"
     PFAM_domain     complement(3339..4226)
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_58_0003"
                     /evalue="2.20E-32"
                     /label="ctg49_58"
                     /locus_tag="ctg49_58"
                     /protein_end="374"
                     /protein_start="78"
                     /score="113.4"
                     /tool="antismash"
                     /translation="AYETYEKKDSIELDIAPITASEGDYFAKVALALQSADTAPDIVCE
                     DTFQLPSDVAAGYLTDLSGYLKDYKEWNDGTFYGALVDGVTYDDGSVYGIPYCTDTRGL
                     WYNKDVFAAAGLDTNWQPKTWQDVLDTCKIIKEKCPDVVPFWCNSGVATGEATSMQTYE
                     MLLYGTGEQLLDNDKWIVKSDNILKSLNFISTIYKDGYGPSLSKVLNGEAGNIASREYL
                     PKGKLAITLDGYWMTGNYKETGAAPWPEYKDKLGIAAMPTSEGQAPGSITMSGGWALSI
                     PQLSDQKDAVMDFIK"
     CDS             complement(4560..5816)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 127.9; E-value:
                     1e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_59"
                     /transl_table=11
                     /translation="LNRMTGKLLIMAWTVVFLLLMGVLVNFSRETNVVPSPEKSKKKLV
                     VMAVYEEDESDEYLKKVLDEYSAISGNPTVVTEYVAQSAFQKQLCLYKDQNSLPDLIIC
                     DSVMTPALQSMDILRDLSDYMTGERTSRFLKHAYGSCVVNGICYGVPFTSNPYVMFYNK
                     DHLARYKKKIPDNMEDFYKLCRETKSLGTYSFGIAVRNKEDIASSFLQMVYSAGGNLRS
                     LDSENSLKLYEILARMRDEGIIAQDVISWNQKDLMQAFSSGYVKIAVARLSSMSLLEHS
                     ASQINYEIAEIPYIQKQTFLFQGDMIGVTEKADEPEALKLLDYITSPEVAESYYKNTYS
                     LSVRTDVCVNPGKVRGLSDGFVQRERNQSVLKSTYSTWFIISDSIAGAMSDFFGDKSMT
                     PQAVAARLQGEIRIAILER"
     PFAM_domain     complement(4776..5603)
                     /aSDomain="SBP_bac_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13416.8"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_59_0004"
                     /evalue="1.70E-21"
                     /label="ctg49_59"
                     /locus_tag="ctg49_59"
                     /protein_end="347"
                     /protein_start="71"
                     /score="77.4"
                     /tool="antismash"
                     /translation="NPTVVTEYVAQSAFQKQLCLYKDQNSLPDLIICDSVMTPALQSMD
                     ILRDLSDYMTGERTSRFLKHAYGSCVVNGICYGVPFTSNPYVMFYNKDHLARYKKKIPD
                     NMEDFYKLCRETKSLGTYSFGIAVRNKEDIASSFLQMVYSAGGNLRSLDSENSLKLYEI
                     LARMRDEGIIAQDVISWNQKDLMQAFSSGYVKIAVARLSSMSLLEHSASQINYEIAEIP
                     YIQKQTFLFQGDMIGVTEKADEPEALKLLDYITSPEVAESYYKNTYSLSVRTDV"
     CDS             complement(5819..7324)
                     /gene_functions="regulatory (smcogs) SMCOG1016:LuxR family
                     DNA-binding response regulator (Score: 88.7; E-value:
                     5.1e-27)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg49_60"
                     /transl_table=11
                     /translation="MRILVVEDEPNTRNGIIKIIETYTGYKVVGGTGDGETGLSEALRL
                     KPDVVITDINMPQMNGLVMIERMRKEGCEAAAVVLTGYSEFEYAQRAIQLSVVEYLLKP
                     LSVEDIISVLKAVENRLSKTRAKTVSPQQLLFSLLTGERKEEVMKQFAGEICYQNGQEI
                     SLFLIQSESILEDTTKQMAELLKESLEANCLTSFFTFLLPYERQILVMILDGQSVWYLK
                     NLFQTRIIKDLREKGEFIISFESINGIGELKDTIRQMQDGLSYSFLFSESCIIDQELIN
                     GLTFERIDYPEYLEHGVRREIKNGNQAGIRRLAGLFKEQVILHRERPEIIKNHTVRFVM
                     AILDTARELMTEKDVDGLYQYLLNDMMKTGIREIFLNNYWKIIGMVTDERDSTAITDNG
                     MILNVIGFIRQNYAREISLTEAAELVGITPEYLSKLFTKEMGINFTAFLGEFRISTAKK
                     LLASGKYKIYEVAELVGYKDTKYFNKVFRSIAGVCPSDYRKGV"
     PFAM_domain     complement(5828..6061)
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_60_0006"
                     /evalue="2.20E-17"
                     /label="ctg49_60"
                     /locus_tag="ctg49_60"
                     /protein_end="499"
                     /protein_start="421"
                     /score="63.2"
                     /tool="antismash"
                     /translation="AELVGITPEYLSKLFTKEMGINFTAFLGEFRISTAKKLLASGKYK
                     IYEVAELVGYKDTKYFNKVFRSIAGVCPSDYRK"
     PFAM_domain     complement(6983..7318)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_60_0005"
                     /evalue="1.10E-23"
                     /label="ctg49_60"
                     /locus_tag="ctg49_60"
                     /protein_end="114"
                     /protein_start="2"
                     /score="83.6"
                     /tool="antismash"
                     /translation="ILVVEDEPNTRNGIIKIIETYTGYKVVGGTGDGETGLSEALRLKP
                     DVVITDINMPQMNGLVMIERMRKEGCEAAAVVLTGYSEFEYAQRAIQLSVVEYLLKPLS
                     VEDIISVL"
     CDS             complement(7345..9093)
                     /locus_tag="ctg49_61"
                     /transl_table=11
                     /translation="LIGRLLDRYKSYHIAKKILIILLAGSIVPLMIMETFTCIIAASTL
                     KRQTDSLMESNMKLSQKGLEDYFSQYDSIIMSVYTENQYALKLEKLNVWDSRNYYLIKK
                     ELEDDMENISYLHPEILGIAVVTLKKECIGYDSVTNSTINSFCFPAKERSWLKVADETF
                     LNTRTVYSDIVNRRGDNGKNRNILYLGHRIADINNYSQGTVGSILICLDEEEIRETYSQ
                     VDRQDRTVSFLCNTKGTIISSNRKELIGTQIDPVMKTRFSSIYTKPVLDGQYVLVTIRD
                     NRELLKDFKYIFEVIILLTILIIITSILIMLRFAKSFQVRVEKITSAMDKAYKGDYTVQ
                     IIHSWQDEFGIIARHFNHMVTKIDQSGKMEKEALLREKNAELKALEAQINPHFLYNTLD
                     AINWIAIENEQFLISKMLKNLANILRYSIHKSNGVVSVRSETEYLKQYIFLQQQRFSFS
                     FHCIMDIDEEVMDLKMHKLLFQPLIENSINHGFPGKSGEDLITITIRKKGERHLVIQVK
                     DNGKGMDPELIYELNHYDYSLSSLEGSIGVRNVIMRIRYYYGDEGRFEIESDGNGTTVR
                     AEILFE"
     PFAM_domain     complement(7360..7662)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_61_0009"
                     /evalue="4.50E-06"
                     /label="ctg49_61"
                     /locus_tag="ctg49_61"
                     /protein_end="578"
                     /protein_start="477"
                     /score="27.2"
                     /tool="antismash"
                     /translation="LFQPLIENSINHGFPGKSGEDLITITIRKKGERHLVIQVKDNGKG
                     MDPELIYELNHYDYSLSSLEGSIGVRNVIMRIRYYYGDEGRFEIESDGNGTTVRAE"
     PFAM_domain     complement(7726..7956)
                     /aSDomain="His_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06580.15"
                     /description="Histidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_61_0008"
                     /evalue="1.70E-23"
                     /label="ctg49_61"
                     /locus_tag="ctg49_61"
                     /protein_end="456"
                     /protein_start="379"
                     /score="82.9"
                     /tool="antismash"
                     /translation="AELKALEAQINPHFLYNTLDAINWIAIENEQFLISKMLKNLANIL
                     RYSIHKSNGVVSVRSETEYLKQYIFLQQQRFS"
     PFAM_domain     complement(8002..8154)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_61_0007"
                     /evalue="3.00E-05"
                     /label="ctg49_61"
                     /locus_tag="ctg49_61"
                     /protein_end="364"
                     /protein_start="313"
                     /score="24.4"
                     /tool="antismash"
                     /translation="FAKSFQVRVEKITSAMDKAYKGDYTVQIIHSWQDEFGIIARHFNH
                     MVTKID"
     CDS             complement(9262..9885)
                     /locus_tag="ctg49_62"
                     /transl_table=11
                     /translation="MRIPKHIGIIPDGNRRWAVENGIKKEEGYDKGISPGMTLYRLCRD
                     LGVEEMTFYGFTADNTKRPAVQREAFSKACVKAVEVLAKENAQLLVVGKTSSAMFPEEL
                     KPYTKRVCFGNGGMKINFLINYSWEWDLGLSDGTIGPKLKTSDVSRMDLIIRWGGRRRL
                     SGFLPVQSVYSDMYVVDDYWPDFKTDHVYKALEWYSRQDVTLGG"
     PFAM_domain     complement(9277..9858)
                     /aSDomain="Prenyltransf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01255.21"
                     /description="Putative undecaprenyl diphosphate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_62_0010"
                     /evalue="2.60E-35"
                     /label="ctg49_62"
                     /locus_tag="ctg49_62"
                     /protein_end="203"
                     /protein_start="9"
                     /score="122.0"
                     /tool="antismash"
                     /translation="IPDGNRRWAVENGIKKEEGYDKGISPGMTLYRLCRDLGVEEMTFY
                     GFTADNTKRPAVQREAFSKACVKAVEVLAKENAQLLVVGKTSSAMFPEELKPYTKRVCF
                     GNGGMKINFLINYSWEWDLGLSDGTIGPKLKTSDVSRMDLIIRWGGRRRLSGFLPVQSV
                     YSDMYVVDDYWPDFKTDHVYKALEWYSRQDV"
     CDS             complement(10001..10141)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_63"
                     /sec_met_domain="TIGR04223 (E-value: 3.3e-12, bitscore:
                     39.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKGNIAAKFMEQVARKSVEMASQSRCMYIYHQPKMPAEFKKFK
                     K"
     aSDomain        complement(10013..10120)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_63_0001"
                     /evalue="8.20E-11"
                     /identifier="TIGR04223"
                     /label="ctg49_63"
                     /locus_tag="ctg49_63"
                     /protein_end="43"
                     /protein_start="7"
                     /score="39.8"
                     /tool="antismash"
                     /translation="AAKFMEQVARKSVEMASQSRCMYIYHQPKMPAEFKK"
     CDS             complement(10243..10563)
                     /locus_tag="ctg49_64"
                     /transl_table=11
                     /translation="LKPYLILIIFLCTLFLIVNLIHLILEKNDNRISNRKIYVINMVTA
                     AVISNCIEWSEMQFERRAAFLGESFISLLNLINILLCLILVLFMLFVKNDKERIHQCQN
                     RE"
     CDS             10826..11566
                     /locus_tag="ctg49_65"
                     /transl_table=11
                     /translation="MLRIAICDDDVLFTGMLEKLIKAEALANGIDIEVDVFFDGSMLTK
                     YVHLGNVFDLIFLDIEMSQENGIEAARRIRLKDKTALLIYISGYEQYLKELFEVEPFRF
                     LSKPLDTAKFSRYFKEAYERINESNVYFQFNFNKEIKKVALKDVVYFESRNRIVYIYLK
                     DGRTEYFYGKLNDVEKELNGNKQRYLRIHQSYLVNYDYVSTMNFSSLVIENGGKSTTLQ
                     ISEDRQKKIRKQLCDLASKKAGLK"
     PFAM_domain     10835..11167
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_65_0011"
                     /evalue="3.10E-13"
                     /label="ctg49_65"
                     /locus_tag="ctg49_65"
                     /protein_end="114"
                     /protein_start="3"
                     /score="49.9"
                     /tool="antismash"
                     /translation="IAICDDDVLFTGMLEKLIKAEALANGIDIEVDVFFDGSMLTKYVH
                     LGNVFDLIFLDIEMSQENGIEAARRIRLKDKTALLIYISGYEQYLKELFEVEPFRFLSK
                     PLDTAKF"
     PFAM_domain     11240..11530
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_65_0012"
                     /evalue="1.50E-15"
                     /label="ctg49_65"
                     /locus_tag="ctg49_65"
                     /protein_end="235"
                     /protein_start="138"
                     /score="57.3"
                     /tool="antismash"
                     /translation="EIKKVALKDVVYFESRNRIVYIYLKDGRTEYFYGKLNDVEKELNG
                     NKQRYLRIHQSYLVNYDYVSTMNFSSLVIENGGKSTTLQISEDRQKKIRKQL"
     CDS             11568..12866
                     /locus_tag="ctg49_66"
                     /transl_table=11
                     /translation="MNILSATVVSPFLSLFYILVIRKCINAFFVPSWKKPTTYIIWVAY
                     YFFQLFLGIRNGISPVLTLLINMIFVFLATSISYSESWKKCALFSFLICAIWMLVEIII
                     HMILNMLHLDDKAGLSGAIISKIVMLVFAIVTGHCLQHKSTGDISFRYMAILLMVPAGS
                     IYIMHNVFLISSTAENELLFSFISGILMMLINYIIFEVFESLAANSEYQKKTLLYEQQL
                     ELCGRQAEEREIQNTQIRLLRHDMKQHLITILGMVNSGKNQDAATYLTALLEKGNSKKI
                     HEISHSGNIVVDSLVNYKCSVARKQNIEFSTNIFIPPTMPFQNGNLTIILGNLLENALE
                     ACRQMKTGHPKIELEMSYQKGILSIVVWNTFEGERFTDGQKHFLTTKKNPAHHGLGLFS
                     IEQAVAACNGEAITQVRGNIFKAVVILYQEPEE"
     PFAM_domain     12540..12845
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_66_0013"
                     /evalue="1.30E-20"
                     /label="ctg49_66"
                     /locus_tag="ctg49_66"
                     /protein_end="426"
                     /protein_start="324"
                     /score="73.3"
                     /tool="antismash"
                     /translation="GNLTIILGNLLENALEACRQMKTGHPKIELEMSYQKGILSIVVWN
                     TFEGERFTDGQKHFLTTKKNPAHHGLGLFSIEQAVAACNGEAITQVRGNIFKAVVIL"
     CDS             12883..13464
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_67"
                     /sec_met_domain="AgrB (E-value: 3.3e-35, bitscore: 114.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERLSIAFTNYILKKEVISKEDYEIYLYGFQSFLELFLNLVCSLC
                     IAAFLHMEVECLLFFLLFIPLRSFNGGLHLKSYFSCLIFSCATMTFILLIVKYYSLTAP
                     VSFLLYFAFMVLIKITGAVDHPNRPVDTDENKTFTHKTDRTLFLSFLAALSFLFLNLEN
                     YIFLEALIYILVFSTLILSKFTGRSNPRKE"
     PFAM_domain     12904..13410
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_67_0014"
                     /evalue="4.40E-33"
                     /label="ctg49_67"
                     /locus_tag="ctg49_67"
                     /protein_end="176"
                     /protein_start="7"
                     /score="114.3"
                     /tool="antismash"
                     /translation="FTNYILKKEVISKEDYEIYLYGFQSFLELFLNLVCSLCIAAFLHM
                     EVECLLFFLLFIPLRSFNGGLHLKSYFSCLIFSCATMTFILLIVKYYSLTAPVSFLLYF
                     AFMVLIKITGAVDHPNRPVDTDENKTFTHKTDRTLFLSFLAALSFLFLNLENYIFLEAL
                     IYILVF"
     CDS             complement(13472..13936)
                     /locus_tag="ctg49_68"
                     /transl_table=11
                     /translation="MEKKLVLEKSAMGIISAWIMDQFGLLFPAVSLLTILMITDYISGM
                     LASKKEALDNPDNNLYGWSSRKSRIGIYKKVSYIFIILAAVSTDYVIYKFSTEIGIKFE
                     HKTIFGLLVSVWLIINELISILENAGRMGARMPEFLQKVLTELRGKMDKD"
     aSDomain        complement(13478..13870)
                     /aSDomain="TIGR01593"
                     /aSTool="tigrfam"
                     /description="holin_tox_secr: toxin secretion/phage lysis
                     holin"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_68_0002"
                     /evalue="6.10E-13"
                     /identifier="TIGR01593"
                     /label="ctg49_68"
                     /locus_tag="ctg49_68"
                     /protein_end="153"
                     /protein_start="22"
                     /score="46.8"
                     /tool="antismash"
                     /translation="FGLLFPAVSLLTILMITDYISGMLASKKEALDNPDNNLYGWSSRK
                     SRIGIYKKVSYIFIILAAVSTDYVIYKFSTEIGIKFEHKTIFGLLVSVWLIINELISIL
                     ENAGRMGARMPEFLQKVLTELRGKMDK"
     PFAM_domain     complement(13493..13885)
                     /aSDomain="Phage_holin_4_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05105.14"
                     /description="Bacteriophage holin family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_68_0015"
                     /evalue="2.30E-28"
                     /label="ctg49_68"
                     /locus_tag="ctg49_68"
                     /protein_end="148"
                     /protein_start="17"
                     /score="98.7"
                     /tool="antismash"
                     /translation="WIMDQFGLLFPAVSLLTILMITDYISGMLASKKEALDNPDNNLYG
                     WSSRKSRIGIYKKVSYIFIILAAVSTDYVIYKFSTEIGIKFEHKTIFGLLVSVWLIINE
                     LISILENAGRMGARMPEFLQKVLTELR"
     CDS             complement(13966..14505)
                     /locus_tag="ctg49_69"
                     /transl_table=11
                     /translation="MGESVHVIIEEIKEGNKEKFLLIVDKMAPLINKYVRLLYKDEKED
                     MHSEFILSLLEAINSMQYYKDDGQCVYFLSRALKNKFLEQYKKSKQHFDSEASVEDEFF
                     TEISMDQPVYDDWMFHEDLKTMLLKTEGKQAVILWDIVFHEESDAVIADRHLVSRQYVN
                     RVRRKFYNLLKDNYYK"
     CDS             complement(14799..15476)
                     /locus_tag="ctg49_70"
                     /transl_table=11
                     /translation="MNKKNFLSCFLVIALTGCSYSGRTAAATAQPQECQTAALVQESLD
                     GTKQEDSWQTAYKDIISHGGGHLPDPYQLRGIDGMNPSVYLGTHDFNGDGIPELILGDG
                     ISVSVYTYENHGLKKEADLYEPEGWYIINELYLQNNCLILVSNGSDGCGYVGFTWQNSA
                     YITGTHDDYNPDRSYLNDVETAYKAFDDVFHITNLEDDCKRSLIKRNKESGDLTWDWSD
                     VRW"
     CDS             complement(15627..15842)
                     /locus_tag="ctg49_71"
                     /transl_table=11
                     /translation="MNAYDEGLEVLETLFARDYQFALATSNDSIPAVRFIDTFYDSGAF
                     YIVTYGKSQKVKEIAGLRLFRSLMRQ"
     CDS             complement(15849..16274)
                     /locus_tag="ctg49_72"
                     /transl_table=11
                     /translation="MNSEIIAKATKIIEEKAVGGDEGYCALALIDMDGYPTTSTISVSK
                     ADGINWLTFCTGFGSDKTKRIERCNKASVCFNAVNHNITLVGTIEVLTDPEIKKEMWYH
                     GLENHFSGPDDPNYCVLRFTTTRYNLFVDWKEAKGGL"
     PFAM_domain     complement(15897..16202)
                     /aSDomain="Pyrid_ox_like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16242.7"
                     /description="Pyridoxamine 5'-phosphate oxidase like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_72_0016"
                     /evalue="2.00E-11"
                     /label="ctg49_72"
                     /locus_tag="ctg49_72"
                     /protein_end="126"
                     /protein_start="24"
                     /score="43.7"
                     /tool="antismash"
                     /translation="CALALIDMDGYPTTSTISVSKADGINWLTFCTGFGSDKTKRIERC
                     NKASVCFNAVNHNITLVGTIEVLTDPEIKKEMWYHGLENHFSGPDDPNYCVLRFTTT"
     CDS             complement(16498..19125)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_73"
                     /sec_met_domain="PPDK_N (E-value: 1.9e-50, bitscore: 165.5,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKWVYLFTEGSADMKNLLGGKGANLAEMTNLGLPVPQGFTITT
                     EVCTQYYEDGKTINDEIMGQIMDHIEKMEKITGKKFGDNDNPLLVSVRSGARASMPGMM
                     DTILNLGLNEQVVEVLAEKSGNPRWAWDCYRRFIQMFSDVVMEVGKKYFEELIDEMKEK
                     KGVTQDVDLTAEDLKELAVQFKEEYKKKIGSDFPIDPKEQLMEAIKAVFRSWDNPRANI
                     YRRDNDIPYSWGTAVNVQMMAFGNMGETSGTGVAFTRDPATGEKHLMGEFLMNAQGEDV
                     VAGVRTPQKIEQLKEVMPEVYHKFVGICSILEDHYKDMQDMEFTIEDKKLYMLQTRNGK
                     RTAKAALKIACDLVDEFMITEEKAVKMIDPRNLDTLLHPQFDAAVLKKTEPVGKALAAS
                     PGAACGKIVFTADDAKAWKERGEKVVLVRLETSPEDIEGMKAAQGILTVRGGMTSHAAV
                     VARGMGTCCVSGCSEIAMNEAAKKFVLAGKEYHEGDWISLDGSTGRIYDGIIPTVDAAI
                     AGEFGRIMSWADKYRKLKVRTNADTPADAKKARELGAEGIGLCRTEHMFFEGDRIDAFR
                     EMICSDTVQEREAALEKILPVQQGDFEALYEALEGNPVTIRFLDPPLHEFVPTEEEDIK
                     KLADTQGKTVEQIKTIIDSLHEFNPMMGHRGCRLAVTYPEIAKMQTKAVIRAAINVQKA
                     HADWNVCPEIMIPLICDEKELRFVKKIVVETADAEIAAAGSKLTYQVGTMIEIPRAALT
                     ADDIAKDAEFFCFGTNDLTQMTYGFSRDDAGKFLNAYYDTKIFESDPFAKLDQTGVGKL
                     METAIKLGKGVRPDMHVGICGEHGGDPSSVEFCHKIGLDYVSCSPFRVPIARLAAAQAA
                     LNNK"
     aSDomain        complement(16510..19116)
                     /aSDomain="TIGR01828"
                     /aSTool="tigrfam"
                     /description="pyru_phos_dikin: pyruvate, phosphate
                     dikinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg49_73_0003"
                     /evalue="0.00E+00"
                     /identifier="TIGR01828"
                     /label="ctg49_73"
                     /locus_tag="ctg49_73"
                     /protein_end="872"
                     /protein_start="3"
                     /score="1400.2"
                     /tool="antismash"
                     /translation="KWVYLFTEGSADMKNLLGGKGANLAEMTNLGLPVPQGFTITTEVC
                     TQYYEDGKTINDEIMGQIMDHIEKMEKITGKKFGDNDNPLLVSVRSGARASMPGMMDTI
                     LNLGLNEQVVEVLAEKSGNPRWAWDCYRRFIQMFSDVVMEVGKKYFEELIDEMKEKKGV
                     TQDVDLTAEDLKELAVQFKEEYKKKIGSDFPIDPKEQLMEAIKAVFRSWDNPRANIYRR
                     DNDIPYSWGTAVNVQMMAFGNMGETSGTGVAFTRDPATGEKHLMGEFLMNAQGEDVVAG
                     VRTPQKIEQLKEVMPEVYHKFVGICSILEDHYKDMQDMEFTIEDKKLYMLQTRNGKRTA
                     KAALKIACDLVDEFMITEEKAVKMIDPRNLDTLLHPQFDAAVLKKTEPVGKALAASPGA
                     ACGKIVFTADDAKAWKERGEKVVLVRLETSPEDIEGMKAAQGILTVRGGMTSHAAVVAR
                     GMGTCCVSGCSEIAMNEAAKKFVLAGKEYHEGDWISLDGSTGRIYDGIIPTVDAAIAGE
                     FGRIMSWADKYRKLKVRTNADTPADAKKARELGAEGIGLCRTEHMFFEGDRIDAFREMI
                     CSDTVQEREAALEKILPVQQGDFEALYEALEGNPVTIRFLDPPLHEFVPTEEEDIKKLA
                     DTQGKTVEQIKTIIDSLHEFNPMMGHRGCRLAVTYPEIAKMQTKAVIRAAINVQKAHAD
                     WNVCPEIMIPLICDEKELRFVKKIVVETADAEIAAAGSKLTYQVGTMIEIPRAALTADD
                     IAKDAEFFCFGTNDLTQMTYGFSRDDAGKFLNAYYDTKIFESDPFAKLDQTGVGKLMET
                     AIKLGKGVRPDMHVGICGEHGGDPSSVEFCHKIGLDYVSCSPFRVPIARLAAAQAAL"
     PFAM_domain     complement(16516..17571)
                     /aSDomain="PEP-utilizers_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02896.20"
                     /description="PEP-utilising enzyme, PEP-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_73_0020"
                     /evalue="1.20E-87"
                     /label="ctg49_73"
                     /locus_tag="ctg49_73"
                     /protein_end="870"
                     /protein_start="518"
                     /score="293.8"
                     /tool="antismash"
                     /translation="GEFGRIMSWADKYRKLKVRTNADTPADAKKARELGAEGIGLCRTE
                     HMFFEGDRIDAFREMICSDTVQEREAALEKILPVQQGDFEALYEALEGNPVTIRFLDPP
                     LHEFVPTEEEDIKKLADTQGKTVEQIKTIIDSLHEFNPMMGHRGCRLAVTYPEIAKMQT
                     KAVIRAAINVQKAHADWNVCPEIMIPLICDEKELRFVKKIVVETADAEIAAAGSKLTYQ
                     VGTMIEIPRAALTADDIAKDAEFFCFGTNDLTQMTYGFSRDDAGKFLNAYYDTKIFESD
                     PFAKLDQTGVGKLMETAIKLGKGVRPDMHVGICGEHGGDPSSVEFCHKIGLDYVSCSPF
                     RVPIARLAAAQA"
     PFAM_domain     complement(17617..17862)
                     /aSDomain="PEP-utilizers"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00391.25"
                     /description="PEP-utilising enzyme, mobile domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_73_0019"
                     /evalue="2.10E-27"
                     /label="ctg49_73"
                     /locus_tag="ctg49_73"
                     /protein_end="503"
                     /protein_start="421"
                     /score="94.8"
                     /tool="antismash"
                     /translation="EKVVLVRLETSPEDIEGMKAAQGILTVRGGMTSHAAVVARGMGTC
                     CVSGCSEIAMNEAAKKFVLAGKEYHEGDWISLDGSTG"
     PFAM_domain     complement(18067..18207)
                     /aSDomain="PPDK_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01326.21"
                     /description="Pyruvate phosphate dikinase, AMP/ATP-binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_73_0018"
                     /evalue="9.60E-10"
                     /label="ctg49_73"
                     /locus_tag="ctg49_73"
                     /protein_end="353"
                     /protein_start="306"
                     /score="38.3"
                     /tool="antismash"
                     /translation="GICSILEDHYKDMQDMEFTIEDKKLYMLQTRNGKRTAKAALKIAC
                     DL"
     PFAM_domain     complement(18241..19074)
                     /aSDomain="PPDK_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01326.21"
                     /description="Pyruvate phosphate dikinase, AMP/ATP-binding
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_73_0017"
                     /evalue="9.50E-49"
                     /label="ctg49_73"
                     /locus_tag="ctg49_73"
                     /protein_end="295"
                     /protein_start="17"
                     /score="166.5"
                     /tool="antismash"
                     /translation="NLLGGKGANLAEMTNLGLPVPQGFTITTEVCTQYYEDGKTINDEI
                     MGQIMDHIEKMEKITGKKFGDNDNPLLVSVRSGARASMPGMMDTILNLGLNEQVVEVLA
                     EKSGNPRWAWDCYRRFIQMFSDVVMEVGKKYFEELIDEMKEKKGVTQDVDLTAEDLKEL
                     AVQFKEEYKKKIGSDFPIDPKEQLMEAIKAVFRSWDNPRANIYRRDNDIPYSWGTAVNV
                     QMMAFGNMGETSGTGVAFTRDPATGEKHLMGEFLMNAQGEDVVAGVRTPQKIEQLK"
     CDS             complement(19350..20663)
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 250.6; E-value: 4.1e-76)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_74"
                     /transl_table=11
                     /translation="MKQVNLLEDPVNKLFARYLLPSISATMVTSIYIVADTLMIGRGVG
                     AIGIAALNILLPLFSLFFATGMLFGAGGGILLSVSKGKMNDLAANQYYTAAFLMAVVMS
                     TVYTVLGHVLFTPVTRFLGSNETMGPYVEEYGRILISGAPAFLFSSFYQVFVRNDKAPR
                     VSMTAVVSGGVFNIILDYILIFPMNMGMAGAAAATVTGSALTLVILLTHLVSKENTLRF
                     VAGAKIGQAAEVVKNGISSFLLDMCNGVVTFLFNRQILSIAGEMGVVVYGIISNSSYIA
                     SSVNNGISQAVQPILATNFGAGKKARLTKVRQLAERTASVSGAVFAVTGFLFPALVTEA
                     FVRPDPEILAMSVPAIRIYFLSFAAMGMNILYTTWFQSVMEPGNALKICLLRGILLNSF
                     LVFLLPVFMGITGVWTVMPVTEVITFAACRIMLKKQEL"
     PFAM_domain     complement(19467..19910)
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_74_0022"
                     /evalue="6.20E-08"
                     /label="ctg49_74"
                     /locus_tag="ctg49_74"
                     /protein_end="399"
                     /protein_start="251"
                     /score="32.6"
                     /tool="antismash"
                     /translation="TFLFNRQILSIAGEMGVVVYGIISNSSYIASSVNNGISQAVQPIL
                     ATNFGAGKKARLTKVRQLAERTASVSGAVFAVTGFLFPALVTEAFVRPDPEILAMSVPA
                     IRIYFLSFAAMGMNILYTTWFQSVMEPGNALKICLLRGILLNSF"
     PFAM_domain     complement(20118..20603)
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_74_0021"
                     /evalue="1.30E-18"
                     /label="ctg49_74"
                     /locus_tag="ctg49_74"
                     /protein_end="182"
                     /protein_start="20"
                     /score="67.2"
                     /tool="antismash"
                     /translation="PSISATMVTSIYIVADTLMIGRGVGAIGIAALNILLPLFSLFFAT
                     GMLFGAGGGILLSVSKGKMNDLAANQYYTAAFLMAVVMSTVYTVLGHVLFTPVTRFLGS
                     NETMGPYVEEYGRILISGAPAFLFSSFYQVFVRNDKAPRVSMTAVVSGGVFNIILDYI"
     CDS             20902..22077
                     /locus_tag="ctg49_75"
                     /transl_table=11
                     /translation="MKKRALALAMAVMMAATLSACGSSNSGTATTAASSAETTTAAEKA
                     AETTGATSVKSDSSDGYELALVTDLGTIDDKSFNQGAWEGMKKYAEENKISYKYYQPQE
                     GTTDSYLETIGLAIEGGAKLVVCPGYLFEEPVFLAQDQYKDVHFILLDGEPHNGDYSEY
                     KTESNVMPILFQEDEPGFLAGYAAVKDGNTKLGFLGGMAVPAVIRYGYGFAEGADYAAK
                     EMGIDNVEIMYNYTGAFAATPEAQSMAASWYQNGTEVIFGCGGAVGNSVMAAAQEKGKK
                     VIGVDVDQSFESDTVITSAMKQLSVSVYDGVKAFYDDKFPGGETSIFSAKNDGIGLPME
                     TSKFTKFTKDDYTKILGELKDGKVTLVQPSQDNNDPTKDLKLEKTKINFVE"
     PFAM_domain     21094..21975
                     /aSDomain="Bmp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02608.16"
                     /description="ABC transporter substrate-binding protein
                     PnrA-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg49_75_0023"
                     /evalue="2.00E-50"
                     /label="ctg49_75"
                     /locus_tag="ctg49_75"
                     /protein_end="358"
                     /protein_start="64"
                     /score="171.6"
                     /tool="antismash"
                     /translation="ALVTDLGTIDDKSFNQGAWEGMKKYAEENKISYKYYQPQEGTTDS
                     YLETIGLAIEGGAKLVVCPGYLFEEPVFLAQDQYKDVHFILLDGEPHNGDYSEYKTESN
                     VMPILFQEDEPGFLAGYAAVKDGNTKLGFLGGMAVPAVIRYGYGFAEGADYAAKEMGID
                     NVEIMYNYTGAFAATPEAQSMAASWYQNGTEVIFGCGGAVGNSVMAAAQEKGKKVIGVD
                     VDQSFESDTVITSAMKQLSVSVYDGVKAFYDDKFPGGETSIFSAKNDGIGLPMETSKFT
                     KFTKDDYTKILGE"
ORIGIN
        1 ctgcttgggc tgaagtgggt caggatttta gttccgtcaa tgccctccca gtaaaaggtg
       61 tcatagggca ttttattaaa ttcattccaa ctgattttgg ttgtcataaa gtaccgtatt
      121 ccgcattttt tcataatctg cggaagtgcg gcggaataac cgaatacatc gggaagccat
      181 aaaatcacgt tgtctgttcc aaactcttcc cgaaagaatt ccttcccgtg aagaaattgc
      241 ctgatcagtg actctccaga ggataaatta cagtccgctt ccacaaacat gccgccttca
      301 gtttcccatc ttccctctgc tacacgcttt ttaatctctt catacacatc gggggcgttc
      361 ttttttacat atttataaag ctggggctga ctggacataa aaatatattc cggatattgt
      421 ctcatcagct ccagaacagt ggaaaagctt ctcactgcct tatcctctgt aacagccaga
      481 gtccacagcc atgcaacatc aatgtgggta tgccccacac agcatatggt cctgctttct
      541 ttgccacagt accggttata aaattcctcc ttcatatagg cggaagcttt ttttaaactc
      601 tcatagtatt ctttcgagta ctcctttctt aaatccagca gattcaaaga ttcatttgct
      661 gccgttaaaa tagcaataca gctgctgtct ccgtcaggca gcagttttgc agtctcataa
      721 ggaacggata catcataaaa atactgttcc gtctcctggt cgagaatgcg gattttagaa
      781 tccattacca gcttaaagtt ctgatctccc gtgaacgcag ataaaataat acgaaaagtc
      841 tctcctgctt ttgcctgttt ggtcaaaagt acttcccggt gatttacatc cagtccctga
      901 cgtctgacac catttacata gatggtaaac tggggattag tggcatccca gaagccttcc
      961 cgtcccgtcc gcagttcata aattacgcac tggtcttccc actcctctgg tatggtgact
     1021 tccgtttcaa accagtaata ttctctgtgt ccaccccaaa gttcttcttt tgaaagcttc
     1081 tcccaggact gcgtatccaa atcactgaca tgctcaaacc gttctgctga tttgagcatc
     1141 cgatactccg ataccggaat atcttctcta taaatcaaag actgtaaatc acttaacagc
     1201 ttgcctattc tctcttttat taaaatcacg tgtaattcct ccttttttat cagcccttgg
     1261 ctgctccggc catgttaaag ccttttgaca tgtaattctg agacagaaca taaaggacaa
     1321 tggacggaac tgcataaact gcggaatacg ccgctaactg tccatagatt accattccat
     1381 gctgaccgaa aaactgataa agtgtcaccg aagcggggaa cttatcaaga gtctgcagca
     1441 aaatataagg aacaaagaaa ttgccccagc taccggaaaa agtgaaaata aatacgacac
     1501 agatacctgg aaacataaga ggtgcgataa tctttcttaa gctgccaaag gcagatgctc
     1561 catccaccca cgcggcttcc tccagctcca ctggcacatt atccataaaa ttcttcatca
     1621 gccagattcc ataaggcatg gaggttgccg tgagaaatag tatgagtcct ccgattttat
     1681 catacagccc tactgtcaga aacattttgt aaaccggaac cattactgct gtaatgggaa
     1741 gtgaggtcat aaataaaatc gtatataaaa atatgttttt ataacgaagt tcgtatcttg
     1801 acaaaggata agccgcaaaa ccggcaatga gcaccaccag tacggactgt cctaatgaaa
     1861 tgagaagccc atttccaaat gctctctgat ttgcctgatt aagcagaatg gttttataat
     1921 tctccatggt ccactgagaa ggcattttca ctgcctggga agcattgaca tcaaaggagg
     1981 ccagtaaaat ccagagaaga ggcagagcaa atattacagc taaaagtgtc aataccacat
     2041 aaggtattgt tttacgaaat ttccaataca tgtcgttgcc tcctttaatc atttctcata
     2101 attctggtat aaaatacgct cagaacaatt ccaatcacca ggaggatcat ggatatggca
     2161 gttccatatc ccagctgctg ggaaataaat gcctgtctgt acataaaaat gggaagagtg
     2221 agggtttttg ttcccggtcc gcctcctgtc atcatatata tcaatccgaa cactccaaga
     2281 gtggacagcg tattcagcat tgtattggtt gcaatggtat ttttaatgca tgggaggata
     2341 atccggatca tggtctgaaa tggtcctgct ccatccactc ttgccgcttc ctcaatatct
     2401 gctggtactc catcaagagc tgactgaaag ttcatcatgg aaaatgctgt tccgtgccag
     2461 atatttgcca gtattaccgt aagcatagga actgcaaata aaaattccac ttgcggcagg
     2521 cgtaaaaaag aaaaaatctg gtttaaagtt ccgctgtctc caaaaaaggt gctgcagcaa
     2581 agggctacta ccacctcagg cataatccag cctgctaaaa agatgggacc tacaattcct
     2641 ctgaaaatcc tgttcttatt tctcatatta agagcgataa taaaacctaa aacctgctgc
     2701 ccaatcaggc ttccaagcag gaataccagc gtgtttacaa tgctgatgcg gacagtcctg
     2761 tctttaaaca tggtaaaata attactcagt ccgataaatt ttaactgcct ggcattctcc
     2821 cctgacaaag ctaagttggt aaaggagtaa tataccgtaa gcagtatggg agcgacaaag
     2881 aaaacaagta gaagcaggac tgacggcatc aacagtaccg atttgttcgc ctcttccaac
     2941 aggccgcttt gttttttctt catagttgcc tccttttgga atgcggtaaa agggaagggc
     3001 aggtacatga ctaacctgcc ctctctgacc tcattttgag tttatttttc cactacattt
     3061 tccgcgccta cgctgttggt cacatctgac ttgtattgtg ccattgcatc ctccggactg
     3121 gtgccggata cgacggattc taccattgtc tgaatgtgag tagtaacggt agtatactgg
     3181 ctgtttctcg gacggtagaa cgctcctgag aggaagccgg tgcaggtttc cataaacggc
     3241 tgagaagaat aagaagcatc tttcgcaatg tcggttcttg tggcaatatt tccctgggca
     3301 atgatggtat ctaaatatac atcatagctc atgcagtgtt tgataaaatc catgactgca
     3361 tccttttgat cggacagctg cggtatggat aatgcccagc cgcctgacat ggtgatgctt
     3421 ccgggcgcct gcccttcact ggttggcatg gctgcgattc caagcttatc tttatactcc
     3481 ggccatggtg cagctccggt ttccttgtaa tttccggtca tccaataacc gtctaaggta
     3541 attgcaagct tgccttttgg taaatattct ctggaggcga tgttgcctgc ctcaccattt
     3601 aaaacttttg acaaggaagg accataacca tctttataaa ttgtactgat gaaatttaaa
     3661 gattttaaaa tattatcgct tttcactatc catttgtcgt tgtcaagaag ctgctctcct
     3721 gtaccataaa gaagcatctc ataggtctgc atggaagttg cttcaccggt tgctactccg
     3781 gaattgcacc agaatggaac cacatccgga catttttctt taatgatttt gcaggtatca
     3841 agaacatcct gccatgtttt tggctgccag ttagtgtcaa gtcctgctgc agcaaataca
     3901 tccttgttat accagagtcc tctggtatct gtgcaatatg gaattccata tacgcttccg
     3961 tcgtcatagg taacgccatc tacaagtgcc ccgtagaagg ttccgtcatt ccattcctta
     4021 tagtccttta aataaccgga aagatcagtt aaatatccgg ctgccacatc tgatggcagc
     4081 tggaaggtgt cttcacatac aatatccggc gccgtgtctg ccgactgaag agccagagcc
     4141 acctttgcaa aataatcccc ctctgatgca gtgatcggtg caatatccag ctcaatagag
     4201 tctttctttt cataggtttc gtaggcatgt tcaaaccact ttttcagcac atcgcttccg
     4261 tcattacgga aggtaatgct gatctttgtt tttcctgctt ccgttgtctt atcagccggt
     4321 ttttccgtct ccttttgtgt tgctgccgct gtgcttccac cctgggtctc cggcttactt
     4381 cctgccccct gacaagccgt taaggaaagc gccattactg aagcaagcgc tgctgcctga
     4441 atccgtttca tttttttcat aataccctct cctttttatt tgttagatga atcatagcat
     4501 aagaattttc cccggtgtat tccaaatttt tagaaaaggg gtgtaaattt aatctctgct
     4561 tacctttcca gaattgcaat tcggatctct ccctgaagcc tggctgcaac cgcctgtgga
     4621 gtcatggatt tgtccccgaa aaagtccgac attgcccccg caatggaatc agatataata
     4681 aaccaagtgg aataagtact ttttaaaaca ctctgatttc gctcccgctg cacaaaacca
     4741 tctgaaagtc cccgcacttt tcccggatta acacaaacat cggttcttac cgatagacta
     4801 taggtgtttt tataatagga ctctgctacc tccggtgagg ttatataatc aagcaatttt
     4861 agcgcctctg gctcatctgc tttctctgta accccgatca tatctccctg aaacagaaat
     4921 gtctgcttct gaatatacgg gatttccgct atttcatagt ttatctgact ggcagagtgt
     4981 tctaaaagcg acatggagct tagcctggca acagcaattt ttacatatcc actggaaaag
     5041 gcctgcatta aatccttctg attccagcta atcacatcct gggcaatgat tccctcatcc
     5101 cgcatccttg caagtatctc atataatttc aggctgtttt ccgaatccag actacgaaga
     5161 ttccctcctg ccgaatagac catctgcaga aaactggaag caatatcttc cttattcctg
     5221 actgcaattc caaagctgta ggtacccaga cttttggtct ctctgcagag cttataaaaa
     5281 tcttccatat tatccggaat tttttttttg tatctggcta aatggtcttt gttataaaac
     5341 atgacataag gattgctggt aaaaggtacc ccatagcaga ttccattcac cacacagctt
     5401 ccataagcat gcttcagaaa acggctggtt ctctcccctg tcatataatc tgacagatcc
     5461 cgtagaatat ccatagactg aagtgcaggc gtcatcacac tgtcacagat aattaagtcc
     5521 ggaaggctgt tctgatcctt ataaaggcaa agctgctttt gaaaggcaga ctgagccaca
     5581 tactcagtga ccaccgtggg attccccgat attgcagaat attcatcaag tacctttttt
     5641 aagtattcat cactttcatc ctcttcataa actgccataa ccaccagctt tttttttgac
     5701 ttttcagggg agggtaccac attggtttcc ctgctgaaat tcaccagaac tcccatcagt
     5761 aaaaggaaaa ccaccgtcca ggccataata agtaatttac cagtcatccg gttcaaagct
     5821 ataccccctt tctgtaatcc gacggacaga ctcctgctat ggagcggaac actttgttaa
     5881 aatatttggt atccttatat cccacaagtt ctgctacttc ataaatttta tatttgccgg
     5941 aagcgagcag tttttttgct gtgctgatgc ggaattctcc caaaaatgca gtgaagttaa
     6001 tccccatctc cttggtaaac agcttgctta agtattccgg agtgattcct accagctccg
     6061 ccgcctctgt aagagatatt tcccttgcat agttctgccg tataaatcca atgacattta
     6121 atatcatccc gttatccgta atagctgtgc tgtcccgttc atctgtcacc ataccgatga
     6181 ttttccagta attatttaaa aatatctctc tgattccggt tttcatcata tcatttaaaa
     6241 gatactgata cagtccgtct acatccttct ctgtcatcag ttctcttgct gtatcaagaa
     6301 tcgccataac aaatcggacc gtgtggtttt ttattatttc aggccgttct ctgtgcaaga
     6361 tgacctgttc cttaaatagc cctgccagac gtctgattcc agcctgattc ccattcttta
     6421 tctccctcct taccccatgc tctaagtact ctggataatc aatcctttca aatgtcagcc
     6481 catttatcag ctcctgatct ataatacagc tttcagagaa taaaaaactg tagcttaatc
     6541 catcctgcat ctgcctgatg gtatccttta attcaccaat tccattaata ctttcaaaac
     6601 tgattataaa ttctcctttt tccctcaggt ccttaataat cctggtctga aacagatttt
     6661 ttaaatacca gacactttgt ccgtctagaa tcataaccaa tatctgcctt tcataaggca
     6721 gaagaaaggt aaaaaaactg gtcaggcagt tagcctccag actctccttt aacagttcgg
     6781 ccatttgttt tgtggtatcc tccagaatac tctccgactg aattaaaaac agagaaatct
     6841 cctgaccgtt ctgatagcag atttctcccg cgaactgctt catgacttcc tcttttcgtt
     6901 ctccggtcaa caaggaaaat aacagctgct gaggtgatac cgtcttcgcc ctggtttttg
     6961 acagtctgtt ttccacagcc ttcagcacac taataatatc ctctacgctt aagggtttta
     7021 acagatattc cacaaccgac agctggatgg cccgctgggc atattcaaat tccgagtaac
     7081 cggtaagtac aacagcggca gcctcacacc cttcttttct catccgttca atcataacaa
     7141 gaccgttcat ctgcggcatg ttaatgtctg taattaccac atcaggcttt aaccgcaaag
     7201 cctctgaaag tcccgtttca ccatcacctg tgcctcccac aaccttgtac ccggtatatg
     7261 tctcaataat tttaatgatt ccgtttctgg tattaggttc atcttctaca acgagaattc
     7321 tcatgccttt ctgcctcctg ccttctattc aaataaaatt tctgccctga ctgtagtccc
     7381 gtttccgtct gattcaattt caaaacgccc ctcatctcca tagtaatacc tgattctcat
     7441 gataacattt cttaccccga tactcccctc cagagagctt aaagaataat cgtaatgatt
     7501 aagctcataa atcagctcag ggtccattcc ttttccattg tccttaacct ggatcaccag
     7561 atgcctttcc ccttttttcc ttatggttat ggtgatcaga tcctctcctg acttaccggg
     7621 aaagccgtga ttaatggaat tttcaataag aggctgaaat aaaagcttat gcatcttaag
     7681 atccattacc tcctcatcaa tatccatgat gcagtggaag gaaaaggaaa aacgctgctg
     7741 ctggagaaaa atatactgct ttaaatactc tgtttcactt cttacactga ccactccatt
     7801 gcttttatgt atactgtatc gcaaaatatt tgccagattc tttaacatct tactaatgag
     7861 aaactgctca ttttctattg cgatccagtt aatggcatcc agggtgttat agagaaaatg
     7921 aggattgatc tgtgcttcca gtgccttaag ttccgcattc ttctcccgta gaagagcttc
     7981 cttttccatt ttgcccgact ggtctatctt tgtaaccatg tgattaaagt gccttgcaat
     8041 tattccaaat tcatcctgcc aggaatggat gatctgaact gtataatccc ctttgtaagc
     8101 cttgtccatg gctgatgtta tcttttctac cctgacctgg aaagattttg caaaccggag
     8161 cataatcaaa atgcttgtta ttataatcag gatggttaat aaaataatga cttcaaaaat
     8221 atatttaaaa tccttcagaa gctctctgtt gtcccgaatg gtaaccagta catattgacc
     8281 atcgagaacc ggcttcgtat aaatgctgga aaaccgtgtc ttcataacag gatcaatttg
     8341 ggttcctata agttctttcc gattactgga tataattgtt ccttttgtat tacaaagaaa
     8401 agaaacagtc ctgtcctgcc ggtccacctg ggaatatgtc tcccgaatct cttcttcatc
     8461 aagacaaatc agaatacttc caactgtccc ctgactgtaa ttgttgatat ctgcaattct
     8521 gtgtcccaga tacagtatat tccggttttt tccgttgtcc ccccttcggt ttacaatatc
     8581 agaatagact gtcctggtat ttaagaaagt ctcgtctgcc acttttagcc agcttctctc
     8641 ttttgccgga aaacagaagc tgtttatggt actgttggta actgaatcat aaccaatgca
     8701 ctcctttttc agtgtaacca ctgcaattcc caaaatttcc gggtgcaggt atgagatatt
     8761 ctccatatca tcttccagct ctttttttat aagatagtaa tttctcgagt cccagacatt
     8821 taatttttcc agtttcagtg catactggtt ttctgtgtag accgacataa taatactgtc
     8881 atactgggaa aagtaatcct ccaatccttt ctgagacagc ttcatattgc tctccatcag
     8941 gctgtctgtc tgtcttttta atgtacttgc cgcaataata cacgtaaatg tttccataat
     9001 cattaacggc acaattgatc ctgccagcag aataataaga attttctttg ctatatgata
     9061 gcttttatac ctatctagta gtcgtccgat caagctttgc tcctttagtt gtgtatttca
     9121 gataatttta tcgtatttta ctaaattatc atagcatatt ttaccaatat ctggagattt
     9181 ttcatataaa taatctcata ttaccacata aaaaaggcag ccccgcaagg ctgccctttc
     9241 atgatataca attctctttt tttacccccc cagggtcaca tcttgtctgg agtaccactc
     9301 cagtgctttg taaacatgat ccgttttaaa atccggccag taatcatcga ctacatacat
     9361 atccgaataa acggactgaa ccggaagaaa accggaaagt cttcttcttc ctccccaccg
     9421 gattatcaga tccattctgg atacatccga ggttttaagc tttgggccta tggtcccgtc
     9481 tgacagtccc aaatcccatt cccagctata attaataagg aagttgattt tcattccccc
     9541 gttaccgaaa cacacccttt tagtatatgg ttttaactct tccggaaaca tggcggaaga
     9601 agtcttccca accaccagaa gctgtgcgtt ctccttagca agcacctcta cagccttcac
     9661 gcaggccttg gaaaatgctt cccgctgtac cgcaggacgt ttggtgttgt ctgcggtaaa
     9721 gccataaaag gtcatttctt ccactcccag atctctgcag agccggtaaa gagtcatgcc
     9781 aggcgagatg cccttatcat acccttcttc tttctttatt ccgttctcca cagcccaacg
     9841 cctgtttccg tcaggaatga ttccgatgtg ttttggaatt ctcattatct gccctccatg
     9901 attggttccc tttgaggaag tcctgttaaa attatagcca attttttcaa aaggttatca
     9961 tgtagggcag aaaattaggt aatttaaaat gccctgatgc ttatttctta aatttcttaa
    10021 actctgccgg catcttcggc tggtgataga tgtacatgca tctgctttga gaagccattt
    10081 ctacagattt tctggctacc tgttccatga atttagctgc aatattacct ttacgttcca
    10141 ttctttctac ctccattatt ataaagacat taagatagtg ccattataca aattcagtag
    10201 atcaaaaatg acaagttgta ataaaaacga cactgctcgt aattattccc gattttggca
    10261 ctgatgaatc ctctctttgt cattcttaac aaaaagcatg aacagcacca gaatcagaca
    10321 taacaaaata ttaataagat taagcaggga tataaaactt tcccccaaaa atgcagccct
    10381 cctttcaaac tgcatttcac tccactctat acaattagaa atgacagcag cagtcaccat
    10441 atttattaca taaatttttc tgttggatat tcgattatca tttttttcca gaatcagatg
    10501 gatcagattt acaattaaaa acagggtaca gagaaaaata attaaaatta aatagggttt
    10561 caattttgtt acctccatgt ttcacaataa aatgtgatat aatattttta gtgcaataag
    10621 aaaatattat atttccattg aaaaaattac agcatgttga aatttcgaat ctgcaagtaa
    10681 tttttaatgg gatcaattag acaaaatgcg acaaaagctc ttatttctcc cttttaatta
    10741 atgggaggta tcgtacgata tacattatat acatgtttca tttttgcaag aataaagtac
    10801 aaagtttaca tggggaaggg taagtatgtt aagaatagca atttgtgatg acgatgttct
    10861 ttttacagga atgttagaga aattaataaa ggcagaagct ttggcgaacg gtattgatat
    10921 tgaagtcgac gtattttttg acggttccat gctaacgaaa tacgtgcatt taggtaatgt
    10981 atttgacctg atttttcttg atatagagat gtcacaggaa aatggaattg aagccgcacg
    11041 ccgcatcagg ctgaaagaca agactgcgtt gttaatttat atttccggat acgaacagta
    11101 tctaaaagaa ttgtttgaag tagaaccgtt ccgttttctt tctaagccgc tggatactgc
    11161 aaaattctcc cggtatttta aagaggcgta tgaacggatc aatgagagca atgtctattt
    11221 tcaatttaac tttaataaag agattaagaa agtggcgtta aaggatgttg tctattttga
    11281 aagccgcaac cgtattgttt atatttattt aaaagatggc agaacggaat atttttacgg
    11341 aaaactcaat gatgtggaga aagagttaaa cggaaacaaa caacgttacc tgcggataca
    11401 ccagtcttat ctcgtaaatt atgattatgt cagcaccatg aatttttcca gtcttgttat
    11461 agaaaatgga ggtaaatcaa ctacactgca gatcagtgaa gacaggcaaa agaaaatccg
    11521 caaacagtta tgtgatctgg ccagtaagaa agcggggtta aaatagtatg aatattcttt
    11581 ctgccactgt tgtaagtcct tttctctcac tattttatat tttggtcata cgtaagtgca
    11641 tcaacgcatt ttttgtgccc tcctggaaaa agcctacgac gtatattatc tgggtggcct
    11701 attatttctt tcagctgttt ctgggtatta gaaacggaat ctcaccagta ctgacacttt
    11761 tgatcaacat gatctttgtc tttcttgcaa ccagtatttc ttattcagaa agctggaaaa
    11821 aatgtgcctt gttctctttt ttaatctgtg caatctggat gctggtggaa attatcatac
    11881 atatgatctt aaatatgctg catttagatg ataaagccgg cctctcaggg gccattatat
    11941 ctaaaatcgt aatgctggtt tttgcaattg taaccgggca ttgtctgcag cataaaagca
    12001 ctggtgatat ttcattccgg tacatggcga ttttgcttat ggtacctgct ggaagtatct
    12061 atattatgca taacgtcttt ctgatcagca gcacagctga aaatgagctt cttttttcct
    12121 ttatatccgg tattttaatg atgcttatta attatattat ttttgaggtg tttgaatctc
    12181 tggcagcaaa ttcggagtat caaaaaaaga ctctgctcta tgaacagcaa ttagagcttt
    12241 gcggcaggca ggcagaggaa cgggagatac aaaatacaca aatccgtctg ctgcgccatg
    12301 acatgaagca gcacttaatc accatattgg gcatggtaaa ttcaggtaaa aatcaagatg
    12361 ccgccactta tctcaccgca cttttagaaa agggaaactc aaaaaaaata cacgaaatat
    12421 cccacagcgg taatattgtg gtggattctc ttgtaaatta taaatgttcc gtcgcccgga
    12481 aacaaaatat agaatttagc accaatattt ttattccccc cacaatgcct ttccagaacg
    12541 gaaatctaac tatcattctt ggcaacctgt tagaaaacgc cctggaagcc tgccgccaga
    12601 tgaaaaccgg gcatccgaaa atcgaactgg aaatgtccta tcagaaggga atcctttcta
    12661 ttgttgtctg gaataccttt gagggggagc gctttacaga cggtcagaaa cattttttga
    12721 ccactaagaa aaatcctgct catcatggac ttggtctgtt ttccatcgag caggctgtag
    12781 ccgcctgcaa cggtgaagcc atcacgcagg ttcggggaaa tatatttaaa gcggttgtga
    12841 tcttatatca ggaaccggaa gaatgaaaag gaggctcata atatggaacg gctgtctatc
    12901 gcatttacta attatatact aaaaaaagaa gttatttcaa aggaagacta tgaaatttat
    12961 ttatatgggt ttcaaagctt tctggaactg tttttaaatc tggtctgcag tctctgcatt
    13021 gcggctttcc tgcatatgga agtagaatgt ctgctgttct ttttattgtt tattcctctc
    13081 cgttccttta acggaggact gcatttaaag tcgtacttct cctgtctgat tttctcctgt
    13141 gccaccatga ctttcatact tctgatcgtg aaatattaca gtctgacagc tcctgtttcg
    13201 tttctgctgt actttgcttt tatggtactg atcaaaatca caggggctgt cgatcatccc
    13261 aaccgcccgg tagacacaga cgaaaacaag acatttactc ataaaactga ccggacactg
    13321 ttcctcagct ttcttgctgc actgagcttt ctatttttga atcttgaaaa ttacattttc
    13381 ttagaggcgc tgatttatat attagtattt tccaccctta tattatccaa attcaccggc
    13441 aggagtaacc cccggaagga gtaatctttt tttagtcttt atccattttg ccccgtaatt
    13501 ccgtgaggac tttttggaga aattcaggca ttctggcacc catccgtccc gcattttcta
    13561 aaatagaaat taattcatta attataagcc agacagacac caataatcca aagattgttt
    13621 tatgctcaaa tttaattccg atctcagtag aaaatttata gatgacataa tccgtactga
    13681 ctgccgccag aatgatgaat atataactta cctttttata gatgccaatc cggcttttcc
    13741 tgctgctcca gccatacaga ttattgtcag ggttgtcaag tgcctccttt ttggaggcca
    13801 gcatacctga tatgtaatcc gtaatcataa gtatggtcaa taaagaaaca gcaggaaata
    13861 aaagtccgaa ttgatccata atccaggcac tgatgattcc cattgcgctt ttttccaaaa
    13921 ccagtttttt ttccataact gcacctcctc caacgtcttc tttttttatt tgtagtagtt
    13981 gtctttcaga agattataaa attttcttct gacccggttc acgtattggc gggataccaa
    14041 atgccggtct gcaatcactg catccgactc ctcatgaaag acgatatccc acaatataac
    14101 agcctgtttc ccttccgtct ttaaaagcat agtttttaga tcttcatgaa acatccagtc
    14161 atcgtaaaca ggctgatcca tgctgatctc agtaaaaaac tcatcctcaa cagaagcctc
    14221 agaatcaaaa tgctgcttgc tttttttata ctgttctaag aatttgtttt ttagggctct
    14281 gcttaaaaaa tatacacatt gcccgtcatc cttataatat tgcattgaat tgatggcctc
    14341 caacagactt agtataaatt ctgaatgcat gtcctctttt tcatctttgt ataaaagacg
    14401 tacatactta ttaatcaatg gtgccatttt atctacaatc agtaagaatt tttccttatt
    14461 accttctttt atttcctcaa taattacatg aacactttct cccattttct tacctcctaa
    14521 aaggcaaaaa gaaaaaaagg gtaatattgt aaactaaatt cttctgaatc tttaattttt
    14581 tcgcataata tgattgtaga taaaaaacta tcaatttatg gaatcacgta aaaaatgccg
    14641 aataacatgg agaaatctcc atattattcg gcattttatc actttatatc attatagtcc
    14701 tattaattct tggttgtatc tttaaattat tcaacaaaaa aagtccggga ctggattctc
    14761 cagaatcctc cccgaacttg ctgcccacct tattcatttt accatcttac atcagaccag
    14821 tcccatgtaa gatcaccgct ctccttattc ctcttaatta aagatctttt acagtcgtct
    14881 tccaggtttg ttatatggaa tacatcatca aaagctttat atgcagtctc aacatcattc
    14941 aaataagacc tgtcaggatt gtaatcatca tgtgtcccgg taatataggc actattctgc
    15001 caggtaaatc ctacatatcc gcatccatcc gatccattgc tcactagaat gaggcaatta
    15061 ttctgtaagt ataattcatt aataatatac cagccttccg gctcataaag gtccgcttcc
    15121 tttttcaatc catgattttc ataagtatac acgctaacag aaatcccatc acccaatatt
    15181 aattcaggaa tcccgtctcc attaaaatca tgagtcccca gatagaccga tggattcatt
    15241 ccatctatac cccttaattg atacgggtca ggcagatgac cgcccccatg acttattata
    15301 tccttatagg cagtctgcca tgagtcttcc tgcttcgtcc cgtctaaaga ctcctgaact
    15361 aaggcagcag tctgacattc ttgcggctgc gctgtggcag ctgctgttct tcctgaatag
    15421 gagcagccgg ttaaagcaat aactaaaaaa caagataaga aatttttttt attcatgagt
    15481 ctttcccctt ttaactttga cattattgtt tcgttgtcac tgggcataat tattttattc
    15541 taccattatt tcaggtcatt atttatacct cgtaattatt ccggttttgc tcgttgaaaa
    15601 agccatagtc tttttactat ggctcttcat tgcctcataa ggctccgaaa caatcttaaa
    15661 ccggcaatct cctttacttt ttgagacttt ccatatgtta caatataaaa ggctccacta
    15721 tcataaaaag tatcaataaa tctgactgct ggaatactat cgtttgatgt agccagcgca
    15781 aactgataat ctcttgcaaa taatgtttct aaaacctcaa gtccttcatc atacgcattc
    15841 atatttgttt ataagccccc cttggcttcc ttccagtcca caaaaagatt gtagcgggtt
    15901 gtagtgaaac gcaaaacaca gtaattggga tcatcaggac cgctgaaatg attttcaagt
    15961 ccatgatacc acatttcttt tttaatttca gggtccgtca atacttctat tgtacccacc
    16021 agcgtaatat tatgattaac tgcattaaaa caaacacttg ctttgttgca tctttcaatt
    16081 cttttggttt tatcactgcc aaaaccagta cagaatgtaa gccagtttat gccgtcagct
    16141 ttagatacgg atattgttga ggttgttgga tagccatcca tgtcaattaa tgctaaagca
    16201 caataaccct catctccacc tacagccttt tcttcaatta tcttagttgc tttagcgatt
    16261 atttctgaat tcatgttata ttcctcccaa ttaattttat aacaattata acatgcataa
    16321 tgcggcagct gtatgtcatg ttttaatcat ggactttcta ttttttatcc ccctccatat
    16381 tatctgtcaa taaaaaagag caaaaaagag accctcatat aaacgtttca gtcaatacaa
    16441 ggatctctat cttattcctg gaaaaaacta tgttcttctc tcagagaaaa tctcatctta
    16501 cttattattt aaagctgcct gtgctgctgc cagtcttgca atcggcacac ggaacggtga
    16561 gcaggataca taatcaaggc caatcttatg gcagaattca acggaagaag gatctccgcc
    16621 gtgctcgccg cagataccta catgcatatc aggacgtact cctttaccta acttgattgc
    16681 agtctccatc agcttgccta cacctgtctg atccagtttt gcaaatgggt cgctctcgaa
    16741 gatcttggta tcgtagtaag cgtttaagaa cttgcctgca tcatcacggg agaagccata
    16801 ggtcatctga gttaagtcat tggtcccgaa gcagaagaat tctgcatctt ttgcaatatc
    16861 atccgcagtc agtgctgctc tcggtatctc aatcatggtt cctacctgat atgttaattt
    16921 gctgcctgct gctgcaatct cagcatctgc agtctcaact acaatcttct tcacaaatcg
    16981 taattccttc tcatcacaga tcagaggaat catgatttca ggacatacat tccagtctgc
    17041 atgtgccttc tgaacgttga ttgcagcacg gattactgcc tttgtctgca ttttagcaat
    17101 ctcaggatat gtaacagcaa gacggcagcc tctatgtccc atcatcgggt tgaactcgtg
    17161 aagtgaatca atgattgtct tgatctgctc tacagtcttg ccctgtgtat ccgccagctt
    17221 tttaatatcc tcttcctctg taggtacaaa ctcatgaaga ggcggatcta agaagcggat
    17281 ggtaacagga tttccttcca gcgcctcgta aagagcctca aaatcaccct gctgtaccgg
    17341 aagaatcttc tccagtgctg cttctctctc ctgaaccgta tcggaacaga tcatctcgcg
    17401 gaatgcgtcg attctgtctc cctcgaagaa catgtgctca gtacggcaaa gaccgattcc
    17461 ctctgcacca agctctctgg ctttctttgc atcagcaggt gtatctgcat tggttctgac
    17521 tttcagcttt ctgtatttat cagcccatga catgattctt ccaaactctc cggcaatagc
    17581 tgcgtctact gtaggaataa ttccatcgta gatccgtccg gtagatccat ccagagaaat
    17641 ccagtctcct tcgtggtatt ccttacctgc aagaacgaac tttttcgctg cttcattcat
    17701 ggcaatctca gaacaaccgg atacgcagca ggttcccatt cctctggcaa ctacagctgc
    17761 atgggaggtc attccccctc ttacagtcag aataccctgg gctgccttca ttccttcaat
    17821 atcttcagga gaagtttcaa gacggactaa aactactttt tcgcctcgtt ccttccatgc
    17881 tttcgcatca tctgcagtga atacaatctt accgcaggct gctccaggag aagcagcaag
    17941 tgcctttcca actggctctg tcttctttaa tactgctgca tcaaactgag gatgaagcag
    18001 agtatctaag tttctcgggt caatcatctt aactgctttt tcctctgtga tcataaactc
    18061 gtctactaaa tcacaggcga tctttaaagc agctttcgct gttcttttac cattacgggt
    18121 ctgaagcata taaagcttct tatcttcaat agtaaactcc atatcctgca tatctttgta
    18181 atgatcttcc agaatgctgc agatacctac aaatttgtga tatacttccg gcataacctc
    18241 ttttaactgt tcgatcttct gcggagttct cacaccggca actacatctt ctccctgggc
    18301 attcattaag aattctccca tcagatgttt ttctccagtc gcaggatcac gggtgaatgc
    18361 cacaccggta ccggaggttt ctcccatgtt tccaaatgcc atcatctgaa cgttaactgc
    18421 ggttccccaa gagtaaggaa tatcgttgtc acggcggtaa atgttcgctc tcgggttgtc
    18481 ccaggaacgg aatacggctt tgatcgcctc cattaactgc tctttgggat caattgggaa
    18541 atcggaaccg atttttttct tatattcttc tttaaactgt actgcaagct cttttaaatc
    18601 ctctgcagtc aggtccacat cctgggtcac gcccttcttt tccttcatct catcaatcag
    18661 ttcttcgaag tacttctttc ccacttccat aactacatca gagaacatct ggataaatct
    18721 tctgtagcag tcccatgccc agcggggatt accagatttt tcagcaagca cttccaccac
    18781 ctgctcattt aatccgagat ttaagatcgt atccatcatg cctggcatgg atgccctggc
    18841 tccggaacga acggaaacca gaagaggatt atcgttatca ccaaactttt tgccggtgat
    18901 tttttccatc ttttcgatat gatccatgat ctgccccatg atctcgtcat taatcgtttt
    18961 cccatcttca taatactgag tacatacctc agtcgtaatc gtaaacccct gcggaaccgg
    19021 cagacctaaa ttggtcatct ctgccaggtt tgcccctttg ccacctaaca ggtttttcat
    19081 atctgcacta ccctcagtga acaaataaac ccattttctt gccataagta aaatcctcct
    19141 caaaagtgta aattatgctg ctcccccgcg ctttccattg cggaaaagcc ctgaaagtat
    19201 tatagcacaa ttaaaggggt agtaaagagg ttttcattga ttatttgaag taattttctc
    19261 ttttttaaat acaattgcat tgaaagcact tacaaagtct gtctttttcc gatatgcgat
    19321 ttttgttcgt atatacgaaa acacattcgt caaagctcct gtttcttcaa cataattcga
    19381 cacgccgcaa aggttattac ttctgtcaca ggcatgactg tccagactcc ggtgattccc
    19441 atgaaaacgg gaaggagaaa aacaaggaag ctgtttaata aaatcccccg aagcagacag
    19501 attttaagag cattcccagg ctccatgact gactgaaacc atgttgtgta taatatattc
    19561 atacccattg cagcaaagga caagaaataa attcttatag ctggaactga catagccaga
    19621 atttctgggt caggccttac aaacgcttcc gttaccaaag ccggaaacaa aaatcctgtc
    19681 actgcgaaca cagctccgga tacagaggct gtcctctctg ccagctgcct cacttttgtt
    19741 aacctggcct ttttacctgc accgaaattc gttgccagaa tgggctggac tgcctgggaa
    19801 ataccattat taacggatga tgcaatatag gaactgttgg atatgattcc gtaaaccacc
    19861 actcccatct ctccggcaat ggaaagaatc tggcggttaa agaggaacgt gacaacccca
    19921 ttgcacatat ccagcaaaaa gctggaaata ccgtttttca ccacttccgc cgcctgaccg
    19981 atttttgctc ctgcaacaaa tcgcagggta ttttcttttg aaaccaggtg agtcagcaga
    20041 atcacaagtg ttaaggccga accggtcaca gtggccgccg cagcccctgc cattcccata
    20101 ttcatgggaa atatgagtat ataatccagg ataatattaa aaactccccc tgacactaca
    20161 gcagtcatag aaactctggg agctttatca ttgcgcacaa atacctgata aaaggaagaa
    20221 aataaaaaag ccggagcacc ggaaatcaat attcttccat attcctccac ataagggccc
    20281 atcgtttcat tacttcccag aaacctggtc acaggagtaa aaagcacatg ccccaaaact
    20341 gtataaactg tactcatcac aacagccatt aaaaatgcag ccgtataata ctgatttgca
    20401 gctaaatcat tcattttccc ttttgatact gaaaggagga ttcctccgcc tgctccaaac
    20461 agcatacctg tggcaaaaaa aagactgaac aggggcagca gtatatttag tgcggcaatt
    20521 ccaatggctc ccacacctct tccaatcatc agagtgtctg ctactatata aattgatgtg
    20581 accattgttg cactaattga gggaagaagg tatcttgcaa ataatttatt cacaggatct
    20641 tccagtaaat ttacttgttt cataattaag tctccttgca tcattcttaa aatagtttaa
    20701 cataatttaa ttaaataaca aggaaaaaga ggaaagagcc tgttaacatt taaaagtaaa
    20761 atcatttcct ttaaaataac tgatattttt atcttagttt ttcatcaaaa tatcgtcgat
    20821 taagattgtc tccattgcca aaatatgata cattaaaggt atctctgaaa atctattaat
    20881 aacaggagga aaaatagaat tatgaagaaa agagctctcg cattagctat ggcagtcatg
    20941 atggctgcaa cactcagcgc atgtggttct tccaactctg gaaccgccac aacagctgcc
    21001 tcttccgcag aaaccaccac tgcagcagaa aaagctgcgg aaaccactgg tgcaacttct
    21061 gtaaagtctg attcatcaga cggatatgaa ctggcgctgg taactgacct tggtactatc
    21121 gacgacaaat catttaacca gggtgcttgg gaaggtatga aaaagtacgc agaggagaac
    21181 aagatttcct acaagtacta tcagcctcag gaaggtacca cagattctta tttagaaaca
    21241 attggtcttg ctattgaagg cggagccaaa ttagttgtat gccctggcta cttatttgaa
    21301 gagccggtat tccttgcaca ggatcagtat aaagatgtac actttattct tcttgacgga
    21361 gaaccacaca acggggatta ttctgaatat aagactgaat ccaatgttat gcctatcctg
    21421 ttccaggagg acgagcctgg tttcttagct ggttatgctg cagtaaaaga cggcaatact
    21481 aagcttggct tcttaggcgg tatggcagtt cctgcagtaa tccgttatgg ttacggattt
    21541 gctgagggtg cagattacgc tgcgaaagaa atgggcattg acaatgttga gattatgtac
    21601 aactataccg gtgctttcgc tgctactccg gaagcacagt ccatggctgc atcctggtat
    21661 cagaacggaa cagaagtcat cttcggctgc ggcggtgctg ttggcaactc tgttatggct
    21721 gctgctcagg aaaagggcaa aaaagtaatc ggtgttgatg tagaccagag cttcgaatct
    21781 gatacagtta tcacttctgc catgaaacag ctttccgttt ctgtatacga tggtgtgaag
    21841 gctttctatg acgacaagtt cccaggcggc gagacaagta ttttctcagc taagaatgat
    21901 ggtattggtc ttcctatgga aacttccaag ttcaccaaat ttacaaaaga tgattacact
    21961 aaaattctcg gtgaattaaa ggatggcaag gtaaccctgg tacagccgtc ccaggataat
    22021 aacgatccga ccaaagactt aaagcttgaa aaaacaaaaa ttaactttgt agaataatcc
    22081 gaagaggtag ccccttcggg ataccacgat gtcagacagc tgacatacca aggaaaggag
    22141 atgccgtttg attcaccagt catatcagat ctggtctctt acggcatctt ctttttgatt
    22201 cagaacttta ttaacctggt accgggtccc agagataggt accgaagtaa gggggatttt
    22261 atggactaca ttattgagat gcttcatatc acaaaagaat ttcccggtat catcgccaat
    22321 gatgacatta cacttcagct gaaaaaaggt gagatacacg ccctcctcgg agaaaacgga
    22381 gcaggtaaat ccactctcat gagtgtttta ttcggattat accagcccga aaaaggtacg
    22441 atccgggttc gtggtaacga agaaaaaatc acaggtccgc tggatgccaa tgcacttggt
    22501 atcggcatgg tgcaccagca ttttaagctg gtagagaatt ttacagtttt acaaaatatt
    22561 gtacttggta tggaaatgac cagacatgga ttcttaaaaa tggatgattc ccgaaaaaag
    22621 gttatggaat taagcgaaaa gtacaaactt tttgtagatc cggatgcatt gatatctgat
    22681 attactgtcg gtatgcagca aagggttgag atcttaaaaa tgctgtaccg ggacaatgaa
    22741 atcatgatat ttgatgaacc taccgcagtt ttaacccctc aggaaatcga tgaactgatg
    22801 cagatcatgc gggatcttgt aaaggaagga aaatccattc tgttcatcac acataagctc
    22861 aatgaaatca aggcggtcgc agaccgctgt tccgttctgc gccgcggtaa atatattgga
    22921 actgtagatg tggcagatac ctccagggaa gagatgtcag agatgatggt gggccgtaag
    22981 gtcaatttaa ccattcagaa aaaagcatct gaacctggcg aagtagtgtt agaggtaaac
    23041 gatttatccg tagaagccaa acgggaagga cagaccaaaa agctggttca tgatgtctcc
    23101 tttcaggtaa ggagaggtga aatcgtctgt attgccggaa tcgacggcaa tgggcagaca
    23161 gagctgatcc atgcaatcac cggcctttct gatccaaatt ccggttctgt cttaattaac
    23221 agagaggata tgacgaaaaa aagtatccgg tataaaaaca cccatggact ctcccacata
    23281 ccggaggacc gtcacaaaca tggtcttgta ctggaataca acctggcata caatctggtt
    23341 ctccagcagt acttcgataa ggaattccag agcggttcat ttttaaagaa tgaccagatc
    23401 tttgattatg cacagaagct gattgaaaat tatgatatcc gaagcagtga gggacccttt
    23461 acca
//
