LOCUS       c00045_NZ_JAWO..       20752 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAWONS010000240.1 Clostridium boliviensis strain E-1 contig00002,
            whole genome shotgun sequence.
ACCESSION   c00045_NZ_JAWO..
VERSION     c00045_NZ_JAWO..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:22:44
            Original ID  :: NZ_JAWONS010000240.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 86904
            Orig. end    :: 107656
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20752
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[96904:97656]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10752
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20752
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20752
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(217..450)
                     /locus_tag="ctg45_86"
                     /transl_table=11
                     /translation="MIRIILSIVFVIICIALSAIILLQEGKSQGLGSIGGMADTYWGRN
                     KGRSMEGKLEKFTKYGAILFFILSLVLNLNIL"
     PFAM_domain     complement(229..438)
                     /aSDomain="SecG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03840.16"
                     /description="Preprotein translocase SecG subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_86_0001"
                     /evalue="1.90E-22"
                     /label="ctg45_86"
                     /locus_tag="ctg45_86"
                     /protein_end="74"
                     /protein_start="4"
                     /score="79.3"
                     /tool="antismash"
                     /translation="ILSIVFVIICIALSAIILLQEGKSQGLGSIGGMADTYWGRNKGRS
                     MEGKLEKFTKYGAILFFILSLVLNL"
     aSDomain        complement(229..441)
                     /aSDomain="TIGR00810"
                     /aSTool="tigrfam"
                     /description="secG: preprotein translocase, SecG subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_86_0001"
                     /evalue="3.60E-17"
                     /identifier="TIGR00810"
                     /label="ctg45_86"
                     /locus_tag="ctg45_86"
                     /protein_end="74"
                     /protein_start="3"
                     /score="60.2"
                     /tool="antismash"
                     /translation="IILSIVFVIICIALSAIILLQEGKSQGLGSIGGMADTYWGRNKGR
                     SMEGKLEKFTKYGAILFFILSLVLNL"
     CDS             complement(524..1693)
                     /locus_tag="ctg45_87"
                     /transl_table=11
                     /translation="MLEDLDIEQIRGRMLYDSGGNPAVEAEVILENGAHGRATVSVFNE
                     ADGEEEADVISEWLAEAILFENAADQENIDRLLMQQFDKKGRGRAGVSALSMAAARAAG
                     AGLGLPLYRYLGGTSAPAMPVPVMSMIDGGDCVKGIDFKEIMIVPLKRGSFAEGLRMGT
                     EIYQTLKRILSINGYDTSVGESGGFAADMKSSEESLHYIMDAVRLSGYDPDSDVSAAIY
                     GNADNLYVKEDGIYRFDKESLKNGIPVHRDQKDMISYYLRLADGFPLGIVMNGLYKNDP
                     DDRNRMYQMLKHRLLMVSDDFFASNGVEVQLKKAGTVTGALNMVCAAKKMGSKVIFSNS
                     DNETEEVFLGDMAAAVGADYIKCGAPCRGENTAKYNELLRIEEFYGQRH"
     PFAM_domain     complement(533..1330)
                     /aSDomain="Enolase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00113.24"
                     /description="Enolase, C-terminal TIM barrel domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_87_0003"
                     /evalue="3.20E-50"
                     /label="ctg45_87"
                     /locus_tag="ctg45_87"
                     /protein_end="387"
                     /protein_start="121"
                     /score="171.2"
                     /tool="antismash"
                     /translation="AMPVPVMSMIDGGDCVKGIDFKEIMIVPLKRGSFAEGLRMGTEIY
                     QTLKRILSINGYDTSVGESGGFAADMKSSEESLHYIMDAVRLSGYDPDSDVSAAIYGNA
                     DNLYVKEDGIYRFDKESLKNGIPVHRDQKDMISYYLRLADGFPLGIVMNGLYKNDPDDR
                     NRMYQMLKHRLLMVSDDFFASNGVEVQLKKAGTVTGALNMVCAAKKMGSKVIFSNSDNE
                     TEEVFLGDMAAAVGADYIKCGAPCRGENTAKYNELLRIEEFYGQ"
     PFAM_domain     complement(1349..1675)
                     /aSDomain="Enolase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03952.18"
                     /description="Enolase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_87_0002"
                     /evalue="2.90E-12"
                     /label="ctg45_87"
                     /locus_tag="ctg45_87"
                     /protein_end="115"
                     /protein_start="6"
                     /score="47.0"
                     /tool="antismash"
                     /translation="IEQIRGRMLYDSGGNPAVEAEVILENGAHGRATVSVFNEADGEEE
                     ADVISEWLAEAILFENAADQENIDRLLMQQFDKKGRGRAGVSALSMAAARAAGAGLGLP
                     LYRYL"
     CDS             complement(1825..4245)
                     /locus_tag="ctg45_88"
                     /transl_table=11
                     /translation="MNTPLSWVKAYVPDLDVTPQEYTDAMTLTGTKVEGYECLDKNLEK
                     IVVGHIQSIVRHPDADKLIVCQVNAGSETVQIVTGASNVKTGDKVPVVLDGGKVAGGHD
                     GGPLPENGIKIKTGKLRGIESCGMMCSIEELGFTNEMYPDAPESGIYILPEDSVPGSDA
                     VELLGLHDSVFEYEVTSNRVDCYSVIGIAREAAATFNKPFIPPVVTAAGNSEDVHDYLK
                     VTVEDSRLCSRYCARMVKNLKLAPSPVWMQRRLAACGIRPINNIVDITNYVMEEYGQPM
                     HAFDYDQLSGHEIVVRCAEDGELFQTLDGQERKLDSTVLMIRDGEKAVGIAGIMGGENS
                     KITDEIHTMVFESACFDGTNIRLSSKKVGLRTDASGKFEKGLDPNNAQAAIDRACQLIE
                     ELGAGEVVGGMIDVYPEKRESKRIAFEPERMNRLLGTDIAPETMLEYYNRLELEYDEKT
                     GEIIIPTFRQDLECMADMAEETARFYGYDKIPVSLPTGEATTGKLSYKLRVEEVAREVA
                     EFSGFSQGMTYSFESPKVFDRLLLPEDSPLRTTVNILNPLGEDYSVMRTTPLHGMLNSL
                     STNFNRRNKNVRLYELANIYLPKSLPLTELPDERMQFTLGFYGDGDFFDMKGVIEEFFD
                     KTGMKLKPHYDPKAGKTFLHPGRQADIIYDGVNIGYLGEIHPEVADNYKIGDRAYVAVI
                     DMPSMIPFTSFDRKYTGIAKYPAVTRDISMVVPKNILVGQIEEVIAQRGGKILESYELF
                     DIYEGAQILAGFKSVAYSITFRAADHTLEEQEVSGVMKKILNGLQALGIELRA"
     PFAM_domain     complement(1831..2106)
                     /aSDomain="FDX-ACB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03147.16"
                     /description="Ferredoxin-fold anticodon binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_88_0008"
                     /evalue="5.20E-25"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="805"
                     /protein_start="713"
                     /score="87.8"
                     /tool="antismash"
                     /translation="KYPAVTRDISMVVPKNILVGQIEEVIAQRGGKILESYELFDIYEG
                     AQILAGFKSVAYSITFRAADHTLEEQEVSGVMKKILNGLQALGIELR"
     aSDomain        complement(1831..4245)
                     /aSDomain="TIGR00472"
                     /aSTool="tigrfam"
                     /description="pheT_bact: phenylalanine--tRNA ligase, beta
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_88_0002"
                     /evalue="3.60E-231"
                     /identifier="TIGR00472"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="805"
                     /protein_start="0"
                     /score="767.6"
                     /tool="antismash"
                     /translation="MNTPLSWVKAYVPDLDVTPQEYTDAMTLTGTKVEGYECLDKNLEK
                     IVVGHIQSIVRHPDADKLIVCQVNAGSETVQIVTGASNVKTGDKVPVVLDGGKVAGGHD
                     GGPLPENGIKIKTGKLRGIESCGMMCSIEELGFTNEMYPDAPESGIYILPEDSVPGSDA
                     VELLGLHDSVFEYEVTSNRVDCYSVIGIAREAAATFNKPFIPPVVTAAGNSEDVHDYLK
                     VTVEDSRLCSRYCARMVKNLKLAPSPVWMQRRLAACGIRPINNIVDITNYVMEEYGQPM
                     HAFDYDQLSGHEIVVRCAEDGELFQTLDGQERKLDSTVLMIRDGEKAVGIAGIMGGENS
                     KITDEIHTMVFESACFDGTNIRLSSKKVGLRTDASGKFEKGLDPNNAQAAIDRACQLIE
                     ELGAGEVVGGMIDVYPEKRESKRIAFEPERMNRLLGTDIAPETMLEYYNRLELEYDEKT
                     GEIIIPTFRQDLECMADMAEETARFYGYDKIPVSLPTGEATTGKLSYKLRVEEVAREVA
                     EFSGFSQGMTYSFESPKVFDRLLLPEDSPLRTTVNILNPLGEDYSVMRTTPLHGMLNSL
                     STNFNRRNKNVRLYELANIYLPKSLPLTELPDERMQFTLGFYGDGDFFDMKGVIEEFFD
                     KTGMKLKPHYDPKAGKTFLHPGRQADIIYDGVNIGYLGEIHPEVADNYKIGDRAYVAVI
                     DMPSMIPFTSFDRKYTGIAKYPAVTRDISMVVPKNILVGQIEEVIAQRGGKILESYELF
                     DIYEGAQILAGFKSVAYSITFRAADHTLEEQEVSGVMKKILNGLQALGIELR"
     PFAM_domain     complement(2158..2781)
                     /aSDomain="tRNA_synthFbeta"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17759.3"
                     /description="Phenylalanyl tRNA synthetase beta chain CLM
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_88_0007"
                     /evalue="6.00E-55"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="696"
                     /protein_start="488"
                     /score="186.0"
                     /tool="antismash"
                     /translation="IPVSLPTGEATTGKLSYKLRVEEVAREVAEFSGFSQGMTYSFESP
                     KVFDRLLLPEDSPLRTTVNILNPLGEDYSVMRTTPLHGMLNSLSTNFNRRNKNVRLYEL
                     ANIYLPKSLPLTELPDERMQFTLGFYGDGDFFDMKGVIEEFFDKTGMKLKPHYDPKAGK
                     TFLHPGRQADIIYDGVNIGYLGEIHPEVADNYKIGDRAYVAVIDM"
     PFAM_domain     complement(2788..2979)
                     /aSDomain="B5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03484.17"
                     /description="tRNA synthetase B5 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_88_0006"
                     /evalue="4.80E-14"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="486"
                     /protein_start="422"
                     /score="52.5"
                     /tool="antismash"
                     /translation="IAFEPERMNRLLGTDIAPETMLEYYNRLELEYDEKTGEIIIPTFR
                     QDLECMADMAEETARFYGY"
     PFAM_domain     complement(3043..3555)
                     /aSDomain="B3_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03483.19"
                     /description="B3/4 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_88_0005"
                     /evalue="3.20E-65"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="401"
                     /protein_start="230"
                     /score="219.2"
                     /tool="antismash"
                     /translation="CSRYCARMVKNLKLAPSPVWMQRRLAACGIRPINNIVDITNYVME
                     EYGQPMHAFDYDQLSGHEIVVRCAEDGELFQTLDGQERKLDSTVLMIRDGEKAVGIAGI
                     MGGENSKITDEIHTMVFESACFDGTNIRLSSKKVGLRTDASGKFEKGLDPNNAQAAIDR
                     ACQLIEEL"
     PFAM_domain     complement(3763..4110)
                     /aSDomain="tRNA_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01588.22"
                     /description="Putative tRNA binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_88_0004"
                     /evalue="1.60E-18"
                     /label="ctg45_88"
                     /locus_tag="ctg45_88"
                     /protein_end="161"
                     /protein_start="45"
                     /score="66.7"
                     /tool="antismash"
                     /translation="IVVGHIQSIVRHPDADKLIVCQVNAGSETVQIVTGASNVKTGDKV
                     PVVLDGGKVAGGHDGGPLPENGIKIKTGKLRGIESCGMMCSIEELGFTNEMYPDAPESG
                     IYILPEDSVPGS"
     CDS             complement(4268..5287)
                     /locus_tag="ctg45_89"
                     /transl_table=11
                     /translation="MKDQLERIKQEALKQIEASDALEKLGDIKVAYLGKKGELTSVLKS
                     MKDVAPEDRPKIGQMVNEAREAIEGKLDAAMAALMKKAREEQLRKEVIDVTLPAKRSRV
                     GHTHPNSIALEEVERIFVGMGYEVIEGPEVEYDHYNFEKLNIPKNHPARDEQDTFYISD
                     NIVLRSQTSPVQVRTMEKGKLPIRMLAPGRVFRSDEVDATHSPSFHQIEGLVIDKNITF
                     ADLKGTLAEFARELFGPETKVKFRPHHFPFTEPSAEMDVTCFKCGGKGCRFCKGSGWIE
                     ILGCGMVHPNVLAMSGIDSNEYSGFAFGVGLERIALLKYEIDDMRLLYENDIRFLKQF"
     PFAM_domain     complement(4271..5011)
                     /aSDomain="tRNA-synt_2d"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01409.22"
                     /description="tRNA synthetases class II core domain (F)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_89_0010"
                     /evalue="3.30E-105"
                     /label="ctg45_89"
                     /locus_tag="ctg45_89"
                     /protein_end="339"
                     /protein_start="92"
                     /score="351.1"
                     /tool="antismash"
                     /translation="IDVTLPAKRSRVGHTHPNSIALEEVERIFVGMGYEVIEGPEVEYD
                     HYNFEKLNIPKNHPARDEQDTFYISDNIVLRSQTSPVQVRTMEKGKLPIRMLAPGRVFR
                     SDEVDATHSPSFHQIEGLVIDKNITFADLKGTLAEFARELFGPETKVKFRPHHFPFTEP
                     SAEMDVTCFKCGGKGCRFCKGSGWIEILGCGMVHPNVLAMSGIDSNEYSGFAFGVGLER
                     IALLKYEIDDMRLLYENDIRFLKQF"
     aSDomain        complement(4271..5173)
                     /aSDomain="TIGR00468"
                     /aSTool="tigrfam"
                     /description="pheS: phenylalanine--tRNA ligase, alpha
                     subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_89_0003"
                     /evalue="5.30E-103"
                     /identifier="TIGR00468"
                     /label="ctg45_89"
                     /locus_tag="ctg45_89"
                     /protein_end="339"
                     /protein_start="38"
                     /score="342.6"
                     /tool="antismash"
                     /translation="LTSVLKSMKDVAPEDRPKIGQMVNEAREAIEGKLDAAMAALMKKA
                     REEQLRKEVIDVTLPAKRSRVGHTHPNSIALEEVERIFVGMGYEVIEGPEVEYDHYNFE
                     KLNIPKNHPARDEQDTFYISDNIVLRSQTSPVQVRTMEKGKLPIRMLAPGRVFRSDEVD
                     ATHSPSFHQIEGLVIDKNITFADLKGTLAEFARELFGPETKVKFRPHHFPFTEPSAEMD
                     VTCFKCGGKGCRFCKGSGWIEILGCGMVHPNVLAMSGIDSNEYSGFAFGVGLERIALLK
                     YEIDDMRLLYENDIRFLKQF"
     PFAM_domain     complement(5024..5224)
                     /aSDomain="Phe_tRNA-synt_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02912.20"
                     /description="Aminoacyl tRNA synthetase class II,
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_89_0009"
                     /evalue="1.30E-22"
                     /label="ctg45_89"
                     /locus_tag="ctg45_89"
                     /protein_end="88"
                     /protein_start="21"
                     /score="79.6"
                     /tool="antismash"
                     /translation="LEKLGDIKVAYLGKKGELTSVLKSMKDVAPEDRPKIGQMVNEARE
                     AIEGKLDAAMAALMKKAREEQL"
     CDS             complement(5642..7714)
                     /gene_functions="other (smcogs) SMCOG1061:methyl-accepting
                     chemotaxis protein (Score: 149.6; E-value: 2.1e-45)"
                     /gene_kind="other"
                     /locus_tag="ctg45_90"
                     /transl_table=11
                     /translation="MNRRIGIKSIGVKMLLGILPVLVLALAFLAKLSESTSSQLIEQQS
                     NSTMESELKASVNGINNDLNAVETTAMNISHIVSASYQTTDLDTYGRAISDIISTNGLI
                     LGSGIWFEPNVYDTSQKYVGPYWYKDGDKVIQTNEYSNDSYDYFNQAYYQSVSGGVKTP
                     VITDPYYDPTLDMMMATCAAPIYDSSSRFIGVVTVDMQLSDIDELIKSIKVGKNGTAML
                     ISAEGVYLSGADGDKVSKAMNMKQDENASLSAAAAEMVANDRGKTAYTEGTKTYNLYYD
                     TVPGVGWIIMIKMPQSELEEPIVLLNEKLMKLSAAALILCIFAVLLQVGSIASGLKKVR
                     KFAGSLAAGDFTVQPLKTRRKDELGQMSSSLNNMFQSNKGVIEQISDQAGDITDASIHL
                     NKVSNDLLLQFSEVKTYMGDVDKAMMSSSAATEELNASLAEVNSSVGILANETEKSSSM
                     AGEIMERAKDIEKKSREAYDNAIVISQEREQDLQMAVQHAKVVERIGDMARLISNTASQ
                     INLLSLNASIEAVRAGEQGRGFAVVAREIGKLAKDTSEIVKEIEGTITDVQNAFTMMLD
                     GSQSMLVFLKDTVTPDYDSFVNVGQQYGKDAVTIEEISNEVEEMAANISQVMQEVRDAI
                     QNVSESVQTTAGNSSMVLGTIEKAYVVVQDMSKMSEKQERIAEELKTVVSGFKLK"
     PFAM_domain     complement(5822..6292)
                     /aSDomain="MCPsignal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00015.23"
                     /description="Methyl-accepting chemotaxis protein (MCP)
                     signalling domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_90_0013"
                     /evalue="1.20E-22"
                     /label="ctg45_90"
                     /locus_tag="ctg45_90"
                     /protein_end="631"
                     /protein_start="474"
                     /score="80.6"
                     /tool="antismash"
                     /translation="EAYDNAIVISQEREQDLQMAVQHAKVVERIGDMARLISNTASQIN
                     LLSLNASIEAVRAGEQGRGFAVVAREIGKLAKDTSEIVKEIEGTITDVQNAFTMMLDGS
                     QSMLVFLKDTVTPDYDSFVNVGQQYGKDAVTIEEISNEVEEMAANISQVMQEV"
     PFAM_domain     complement(6587..6727)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_90_0012"
                     /evalue="6.00E-06"
                     /label="ctg45_90"
                     /locus_tag="ctg45_90"
                     /protein_end="376"
                     /protein_start="329"
                     /score="26.6"
                     /tool="antismash"
                     /translation="GSIASGLKKVRKFAGSLAAGDFTVQPLKTRRKDELGQMSSSLNNM
                     FQ"
     PFAM_domain     complement(6842..7594)
                     /aSDomain="dCache_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02743.20"
                     /description="Cache domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_90_0011"
                     /evalue="7.30E-23"
                     /label="ctg45_90"
                     /locus_tag="ctg45_90"
                     /protein_end="291"
                     /protein_start="40"
                     /score="81.4"
                     /tool="antismash"
                     /translation="IEQQSNSTMESELKASVNGINNDLNAVETTAMNISHIVSASYQTT
                     DLDTYGRAISDIISTNGLILGSGIWFEPNVYDTSQKYVGPYWYKDGDKVIQTNEYSNDS
                     YDYFNQAYYQSVSGGVKTPVITDPYYDPTLDMMMATCAAPIYDSSSRFIGVVTVDMQLS
                     DIDELIKSIKVGKNGTAMLISAEGVYLSGADGDKVSKAMNMKQDENASLSAAAAEMVAN
                     DRGKTAYTEGTKTYNLYYDTVPGVGWIIM"
     CDS             8055..8366
                     /locus_tag="ctg45_91"
                     /transl_table=11
                     /translation="MDQDYINKRITELRLKKGVAEHKMSLELGHSRSYVQSISSGRSLP
                     SMAEFLAICEYLSVTPKDFFDNDNPNPPLVKDTIDKLKTLPESDLLLILTIINRLQSQ"
     PFAM_domain     8088..8243
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_91_0014"
                     /evalue="1.70E-06"
                     /label="ctg45_91"
                     /locus_tag="ctg45_91"
                     /protein_end="63"
                     /protein_start="11"
                     /score="28.1"
                     /tool="antismash"
                     /translation="ELRLKKGVAEHKMSLELGHSRSYVQSISSGRSLPSMAEFLAICEY
                     LSVTPKD"
     CDS             complement(8447..8620)
                     /locus_tag="ctg45_92"
                     /transl_table=11
                     /translation="MINEQTFQDLYGYFFGMINRGDLDEIYARALEAIPTIVSLQEINE
                     FKTTVSAASTNP"
     CDS             complement(8663..9250)
                     /locus_tag="ctg45_93"
                     /transl_table=11
                     /translation="MCEDEKLIDDRHLERINRFTSIETGIYVEGELLQFCEVRMFDNKV
                     GLFLPTVFKDMKAEDAKRKYFSEQRPEIIKTNEDGTVNFSFSMVEREIKPEQLGSVIQE
                     FYLVLKRFQPMSVCLDDGTELDNKVPFAWMEFISTALDDNLYNMLIIYPVGKKLLMVMF
                     NSPFEKRLDWGSCLCKIRKSITIYNNVNEVDY"
     CDS             complement(9272..9742)
                     /locus_tag="ctg45_94"
                     /transl_table=11
                     /translation="MVQNKRNNESYYQYRASCSIRKEDGTEEIKNYELETDILYGDLHF
                     WNRLYYLKKSQNMLFDFASREPGIVKCRILQERLVLIPRFTYRSHKTAGKKGSLFKRLL
                     LVIEVIVLLLLNMMWASVAEEKKVEIYANDNKMTDIVEMGVDNISQCIADKD"
     CDS             complement(10001..10591)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_95"
                     /sec_met_domain="AgrB (E-value: 2.7e-37, bitscore: 122.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQRISNGIVSWQIKKNLLKDNQRSLYLYAYEVLLNQIINIVVAV
                     VIAVILRAPMPVLVFLVSYIPLRSYCGGYHAKTNGVCTVVSAILIIITCLLEMYIVGTA
                     ALYLPIAGFLISGILIFIFAPVADNNKLLDEEETRRYRLKSRQLWLAEVIAGGIFWFVN
                     SRICVVLAISHLLLSIMLVYGVLKNSKMGMKEL"
     PFAM_domain     complement(10049..10573)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_95_0015"
                     /evalue="2.30E-35"
                     /label="ctg45_95"
                     /locus_tag="ctg45_95"
                     /protein_end="181"
                     /protein_start="6"
                     /score="121.7"
                     /tool="antismash"
                     /translation="NGIVSWQIKKNLLKDNQRSLYLYAYEVLLNQIINIVVAVVIAVIL
                     RAPMPVLVFLVSYIPLRSYCGGYHAKTNGVCTVVSAILIIITCLLEMYIVGTAALYLPI
                     AGFLISGILIFIFAPVADNNKLLDEEETRRYRLKSRQLWLAEVIAGGIFWFVNSRICVV
                     LAISHLLLSIML"
     CDS             complement(10591..10752)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_96"
                     /sec_met_domain="TIGR04223 (E-value: 3e-12, bitscore: 41.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLLNALKGKVSMVNVMNTCALLVAAYTMNVTCFWAHHQPEVPE
                     EAKSLRKF"
     aSDomain        complement(10609..10710)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_96_0004"
                     /evalue="3.50E-11"
                     /identifier="TIGR04223"
                     /label="ctg45_96"
                     /locus_tag="ctg45_96"
                     /protein_end="48"
                     /protein_start="14"
                     /score="41.0"
                     /tool="antismash"
                     /translation="VNVMNTCALLVAAYTMNVTCFWAHHQPEVPEEAK"
     CDS             complement(10822..12171)
                     /locus_tag="ctg45_97"
                     /transl_table=11
                     /translation="MGNDLFSVSRLLFCGADVYMMFRFFAAIYPFKIFGKKRQIISIVI
                     TLLIFFENAIGSVSLNFITVPLFCYIYALLLFKISFSNGIAYTIIYFAFVGGKEVLFEL
                     LYRFLSYNLPIYIPPWFTSGGIYFLILEYIVGFLFLLYIEKYIKKINIRNNNVFSWYLL
                     IVPVLSLAISSSFLYMDFPKSIVLQIFMCGGAVLLYLSNAAIFIILEKYTDMMNKIKYA
                     ELYSVKREMENDHFQNILKINDHYRCFMHDVHSYFNSFRLLALNGENQKIVEIIDELKG
                     KIQDEINIVIYSGNPVFNAILSERVSKAKELGVEFSIFIEKNINLDFISDSDLISMFGN
                     LLDNALEAASKCEPQKRVVHIKLFMGTNYFLIFRIENSFKVKAIKEGDKLLSTKEDSKH
                     HGLGVGIVTSLAEKYGGSLNLVQKEAFFITTLTISAFTEDRCANFGTQRV"
     PFAM_domain     complement(10873..11187)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_97_0016"
                     /evalue="1.50E-22"
                     /label="ctg45_97"
                     /locus_tag="ctg45_97"
                     /protein_end="433"
                     /protein_start="328"
                     /score="79.5"
                     /tool="antismash"
                     /translation="ISDSDLISMFGNLLDNALEAASKCEPQKRVVHIKLFMGTNYFLIF
                     RIENSFKVKAIKEGDKLLSTKEDSKHHGLGVGIVTSLAEKYGGSLNLVQKEAFFITTLT
                     I"
     CDS             complement(12173..12949)
                     /locus_tag="ctg45_98"
                     /transl_table=11
                     /translation="MFEIAICDDSMGDRERLIERIGKNMPESDKFRIHEYDSGISLLSA
                     IKNIRFSIIFLDVQMNEMNGEETAVRVRELDNNVILVFNTGFAEPSPRSFEVQPYRYIM
                     KNMTDELMDRYIRDSLDKMIELGQAPLLTANVNRERLFLRADDIVYIEKFKKNTRVHIS
                     ESSIRIYGIKEIDSSEIPDIRVPDKLETIYERLKKYGFGYPHDSYIINFKYLVYCTSKI
                     LRLKDVDTMFQITRSKAQEFHMLKEEFMLSKYKDGN"
     PFAM_domain     complement(12620..12907)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_98_0017"
                     /evalue="8.20E-09"
                     /label="ctg45_98"
                     /locus_tag="ctg45_98"
                     /protein_end="110"
                     /protein_start="14"
                     /score="35.7"
                     /tool="antismash"
                     /translation="ERLIERIGKNMPESDKFRIHEYDSGISLLSAIKNIRFSIIFLDVQ
                     MNEMNGEETAVRVRELDNNVILVFNTGFAEPSPRSFEVQPYRYIMKNMTDE"
     CDS             complement(13098..14843)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     300.6; E-value: 1.4e-91)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 325; E-value: 1.5e-98)"
                     /gene_kind="transport"
                     /locus_tag="ctg45_99"
                     /transl_table=11
                     /translation="MNIKRHKTTVKRILNKIGKYKWSVMASLFCAFLTVVFTLYIPILI
                     GRAIDCIAGAGKVDFKTMGVILTQMGIVILVTATAQWVMSHINNQITYRVVKDIRTQAF
                     NKLESLPLKYIDSHAHGDIISRIIADIDQFSDGLLMGFTQLFTGVLTILGTLVFMFYIN
                     PLIGALVVLVTPLSLFVASFIAKRTYSMFRMQSQTRGVMTSLVEEMLGNQKVVKAFAYE
                     DEAQKKFETINEELRVWGLKATFFSSITNPATRFVNSLVYACVGIAGAIAAVNGFLTVG
                     QLSSFLSYANQYTKPFNEISGVVTELQNALASAARVFELIDEESEIPDDGQAVVLKNSR
                     GEVVLEHVDFSYNQEVRLIEDMNLCAAQGKRIAIVGPTGCGKSTVINLLMRFYDVNAGA
                     IKVDGNDVRHITRESLRSSYGMVLQETWLKTGTIRENIAYGKSDASEEEIVTAAKEAHA
                     HSFISRMPQGYDTIISEDGGNLSQGQKQLLCIARVMLCLPPILILDEATSSIDTRTELK
                     IQKAFAKMMEGRTSFIVAHRLSTIKEADVILVMREGHIIEQGTHEDLLSENGFYAQLYN
                     SQFAV"
     PFAM_domain     complement(13320..13766)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_99_0019"
                     /evalue="6.10E-34"
                     /label="ctg45_99"
                     /locus_tag="ctg45_99"
                     /protein_end="508"
                     /protein_start="359"
                     /score="117.6"
                     /tool="antismash"
                     /translation="EDMNLCAAQGKRIAIVGPTGCGKSTVINLLMRFYDVNAGAIKVDG
                     NDVRHITRESLRSSYGMVLQETWLKTGTIRENIAYGKSDASEEEIVTAAKEAHAHSFIS
                     RMPQGYDTIISEDGGNLSQGQKQLLCIARVMLCLPPILILDEATS"
     PFAM_domain     complement(13956..14771)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_99_0018"
                     /evalue="1.80E-47"
                     /label="ctg45_99"
                     /locus_tag="ctg45_99"
                     /protein_end="296"
                     /protein_start="24"
                     /score="162.4"
                     /tool="antismash"
                     /translation="MASLFCAFLTVVFTLYIPILIGRAIDCIAGAGKVDFKTMGVILTQ
                     MGIVILVTATAQWVMSHINNQITYRVVKDIRTQAFNKLESLPLKYIDSHAHGDIISRII
                     ADIDQFSDGLLMGFTQLFTGVLTILGTLVFMFYINPLIGALVVLVTPLSLFVASFIAKR
                     TYSMFRMQSQTRGVMTSLVEEMLGNQKVVKAFAYEDEAQKKFETINEELRVWGLKATFF
                     SSITNPATRFVNSLVYACVGIAGAIAAVNGFLTVGQLSSFLSYANQYTKP"
     CDS             complement(14845..16575)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 344.1; E-value:
                     2.5e-104)"
                     /gene_kind="transport"
                     /locus_tag="ctg45_100"
                     /transl_table=11
                     /translation="MKKLLKYLSNYKRESILGPLFKLLEASFELLVPLVMAAIIDIGIK
                     NHDVTYILSMGGLLVLLGIIGLTCSITAQYFAAKAAAGFGTSLRNDLFSHINTLSFQEI
                     DTIGTATLITRMTSDVNQVQSGVNLFLRLFLRSPFVVFGAMIMAFTIDIKAALIFAVSI
                     PVLSVVVFGIMLFSMPLYKKVQKQLDRVLLAARENLGGVRVIRAFNRQNDEVRRFDEEN
                     GMLVKLQVFVGKISALMNPFTYVIINLAIIVLINTGANRVQTGNITQGQVVALVNYMSQ
                     ILVELVKLANLIITISKALACANRISSVFSMEPGIKDTNHNEVKGKTDSPKVEFNQVSL
                     FYQGAKSESLRGIGFCAKKGETIGIIGGTGSGKSTLVNVIPRFYDVSQGSVRVEGIDVR
                     EYPLGQLREMVGIVPQKAVLFKGSIRENMQWGKKDASDEDIYRALTIAQAKEFVEEKGE
                     GLDFLIQAGGKNLSGGQRQRLTIARAIVKNPQILILDDSASALDFATDARLRKAIKEET
                     RDMTVFLVSQRASTIKNADSIVVLEDGRMAGCGKHGELMESCEVYREICLSQLSEKEVQ
                     "
     PFAM_domain     complement(15085..15525)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_100_0021"
                     /evalue="2.30E-30"
                     /label="ctg45_100"
                     /locus_tag="ctg45_100"
                     /protein_end="497"
                     /protein_start="350"
                     /score="106.0"
                     /tool="antismash"
                     /translation="RGIGFCAKKGETIGIIGGTGSGKSTLVNVIPRFYDVSQGSVRVEG
                     IDVREYPLGQLREMVGIVPQKAVLFKGSIRENMQWGKKDASDEDIYRALTIAQAKEFVE
                     EKGEGLDFLIQAGGKNLSGGQRQRLTIARAIVKNPQILILDDS"
     PFAM_domain     complement(15727..16530)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_100_0020"
                     /evalue="1.10E-42"
                     /label="ctg45_100"
                     /locus_tag="ctg45_100"
                     /protein_end="283"
                     /protein_start="15"
                     /score="146.7"
                     /tool="antismash"
                     /translation="ILGPLFKLLEASFELLVPLVMAAIIDIGIKNHDVTYILSMGGLLV
                     LLGIIGLTCSITAQYFAAKAAAGFGTSLRNDLFSHINTLSFQEIDTIGTATLITRMTSD
                     VNQVQSGVNLFLRLFLRSPFVVFGAMIMAFTIDIKAALIFAVSIPVLSVVVFGIMLFSM
                     PLYKKVQKQLDRVLLAARENLGGVRVIRAFNRQNDEVRRFDEENGMLVKLQVFVGKISA
                     LMNPFTYVIINLAIIVLINTGANRVQTGNITQGQVVALVNYMSQIL"
     CDS             16693..17574
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 173.2; E-value: 1.2e-52)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg45_101"
                     /transl_table=11
                     /translation="MIPINSKQLYYFTVVSETGSFTAAAKKLGISQPPLSKQIMLLEEE
                     MGVKLLERRSKKAELTEAGTYLYFKAKDILSMMGTVSDDLKHFPSSARGVLKLGTISSS
                     GTVLLDFLKNFTSAHPGVRFEVTEGNTYELLEKMKNGLVECSIIRTPFNPEGLKCVYGK
                     KEPIMAVGNPAFFPEFTGNKVSLTELKGKPLIYYRRFDSIISLAFQNSGIKPDIFCRND
                     DARTCLQWAKAGMGIALVPQSISLTLGQENLLFREIDSSDTVTQIAAVYKKNGYVSNIA
                     REFVTSFGDQSN"
     PFAM_domain     16711..16884
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_101_0022"
                     /evalue="6.10E-21"
                     /label="ctg45_101"
                     /locus_tag="ctg45_101"
                     /protein_end="64"
                     /protein_start="6"
                     /score="74.2"
                     /tool="antismash"
                     /translation="KQLYYFTVVSETGSFTAAAKKLGISQPPLSKQIMLLEEEMGVKLL
                     ERRSKKAELTEAG"
     PFAM_domain     16966..17556
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_101_0023"
                     /evalue="3.20E-30"
                     /label="ctg45_101"
                     /locus_tag="ctg45_101"
                     /protein_end="288"
                     /protein_start="91"
                     /score="105.2"
                     /tool="antismash"
                     /translation="ARGVLKLGTISSSGTVLLDFLKNFTSAHPGVRFEVTEGNTYELLE
                     KMKNGLVECSIIRTPFNPEGLKCVYGKKEPIMAVGNPAFFPEFTGNKVSLTELKGKPLI
                     YYRRFDSIISLAFQNSGIKPDIFCRNDDARTCLQWAKAGMGIALVPQSISLTLGQENLL
                     FREIDSSDTVTQIAAVYKKNGYVSNIAREFVTSF"
     CDS             complement(17575..18465)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_102"
                     /sec_met_domain="PF04055 (E-value: 7e-13, bitscore: 43.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYIPAKTIVTKTKTSGWFGIDYNMNIYRGCSHGCIYCDSRSDCY
                     RIDHFDTVRVKEDALRIIRDDLRRKVKTGVVGTGAMSDPYNPLENELKLTRHALELIDA
                     FGFGAAIATKSTLLQRDIDILKSIADHSPVILKVTVTTSDDNLASKIEPRVSRPSDRLS
                     LIAALKDQGLFAGILLMPVLPFLEDNEDNISSIIAAAKEAGADFIYPAFGVTLRNNQRE
                     WYYDRLGELFPGDNLAEQYMKRYGNNYQCTSPRARKLWQVFSEECSRNRILYKMPDIIH
                     AYKKNYQITQLSLFD"
     PFAM_domain     complement(17896..18393)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_102_0024"
                     /evalue="4.20E-11"
                     /label="ctg45_102"
                     /locus_tag="ctg45_102"
                     /protein_end="190"
                     /protein_start="24"
                     /score="43.6"
                     /tool="antismash"
                     /translation="MNIYRGCSHGCIYCDSRSDCYRIDHFDTVRVKEDALRIIRDDLRR
                     KVKTGVVGTGAMSDPYNPLENELKLTRHALELIDAFGFGAAIATKSTLLQRDIDILKSI
                     ADHSPVILKVTVTTSDDNLASKIEPRVSRPSDRLSLIAALKDQGLFAGILLMPVLPFLE
                     DNE"
     CDS             18574..19398
                     /locus_tag="ctg45_103"
                     /transl_table=11
                     /translation="MIRFLLRCKQIYDKYTKDEMTVYAAQASYFTIIAAFPFMMLLLAM
                     IQFIPSITKANLLQLLVTVIPSTLEIDSVIVNVIEDLYTKSPAAILSVTAIAAIWSASK
                     GMLSIERGLNRVFGQEKKRGYFMTRVVCAGYTVVFIIICTLTLVLLVLGSSIQAFMNRH
                     FPILAEITQHVISFRTMLLFILTLCFAMLYTYVPEKKQHFTRQLPGAVFSTLGWIAFSF
                     AFSIYFSNFSNYSVMYGSLTAIVLIMLWLYSCICILFFGAEINYYYSENRKE"
     aSDomain        18598..19374
                     /aSDomain="TIGR00765"
                     /aSTool="tigrfam"
                     /description="yihY_not_rbn: YihY family inner membrane
                     protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_103_0005"
                     /evalue="1.70E-35"
                     /identifier="TIGR00765"
                     /label="ctg45_103"
                     /locus_tag="ctg45_103"
                     /protein_end="267"
                     /protein_start="8"
                     /score="121.1"
                     /tool="antismash"
                     /translation="KQIYDKYTKDEMTVYAAQASYFTIIAAFPFMMLLLAMIQFIPSIT
                     KANLLQLLVTVIPSTLEIDSVIVNVIEDLYTKSPAAILSVTAIAAIWSASKGMLSIERG
                     LNRVFGQEKKRGYFMTRVVCAGYTVVFIIICTLTLVLLVLGSSIQAFMNRHFPILAEIT
                     QHVISFRTMLLFILTLCFAMLYTYVPEKKQHFTRQLPGAVFSTLGWIAFSFAFSIYFSN
                     FSNYSVMYGSLTAIVLIMLWLYSCICILFFGAEINYY"
     PFAM_domain     18622..19386
                     /aSDomain="Virul_fac_BrkB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03631.17"
                     /description="Virulence factor BrkB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_103_0025"
                     /evalue="1.50E-53"
                     /label="ctg45_103"
                     /locus_tag="ctg45_103"
                     /protein_end="271"
                     /protein_start="16"
                     /score="182.2"
                     /tool="antismash"
                     /translation="KDEMTVYAAQASYFTIIAAFPFMMLLLAMIQFIPSITKANLLQLL
                     VTVIPSTLEIDSVIVNVIEDLYTKSPAAILSVTAIAAIWSASKGMLSIERGLNRVFGQE
                     KKRGYFMTRVVCAGYTVVFIIICTLTLVLLVLGSSIQAFMNRHFPILAEITQHVISFRT
                     MLLFILTLCFAMLYTYVPEKKQHFTRQLPGAVFSTLGWIAFSFAFSIYFSNFSNYSVMY
                     GSLTAIVLIMLWLYSCICILFFGAEINYYYSEN"
     CDS             complement(19459..20388)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081:cysteine synthase (Score: 359.9; E-value:
                     1.5e-109)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_104"
                     /transl_table=11
                     /translation="MENIKKSARELIGKTPLLELSNYQKKHGLKASVIAKLEYFNPAGS
                     VKDRAALSMIEDGEKTGRIKPGATIIEPTSGNTGIGIASIAAMKGYRAILIMPETMSVE
                     RRNLLKAYGAEIVLTEGTKGMKGAIDKAAQLQKEIEGSVILGQFENPANPAIHRETTGP
                     EIWEDTDGIVDVFVAGIGTGGTITGVGEYLKSKNPDIRIIGVEPAGSPILSGGKPGPHG
                     LQGIGAGFVPDILNTEIYDEIIPVENQEAYETGKEIAQTEGILVGISSAAAVWAAREAA
                     KRPEFEGKRIIVLLPDTGDRYLSTPLFS"
     aSDomain        complement(19465..20361)
                     /aSDomain="TIGR01139"
                     /aSTool="tigrfam"
                     /description="cysK: cysteine synthase A"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_104_0006"
                     /evalue="1.80E-135"
                     /identifier="TIGR01139"
                     /label="ctg45_104"
                     /locus_tag="ctg45_104"
                     /protein_end="308"
                     /protein_start="9"
                     /score="449.0"
                     /tool="antismash"
                     /translation="ELIGKTPLLELSNYQKKHGLKASVIAKLEYFNPAGSVKDRAALSM
                     IEDGEKTGRIKPGATIIEPTSGNTGIGIASIAAMKGYRAILIMPETMSVERRNLLKAYG
                     AEIVLTEGTKGMKGAIDKAAQLQKEIEGSVILGQFENPANPAIHRETTGPEIWEDTDGI
                     VDVFVAGIGTGGTITGVGEYLKSKNPDIRIIGVEPAGSPILSGGKPGPHGLQGIGAGFV
                     PDILNTEIYDEIIPVENQEAYETGKEIAQTEGILVGISSAAAVWAAREAAKRPEFEGKR
                     IIVLLPDTGDRYLSTPLF"
     aSDomain        complement(19465..20361)
                     /aSDomain="TIGR01136"
                     /aSTool="tigrfam"
                     /description="cysKM: cysteine synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg45_104_0007"
                     /evalue="7.10E-132"
                     /identifier="TIGR01136"
                     /label="ctg45_104"
                     /locus_tag="ctg45_104"
                     /protein_end="308"
                     /protein_start="9"
                     /score="437.2"
                     /tool="antismash"
                     /translation="ELIGKTPLLELSNYQKKHGLKASVIAKLEYFNPAGSVKDRAALSM
                     IEDGEKTGRIKPGATIIEPTSGNTGIGIASIAAMKGYRAILIMPETMSVERRNLLKAYG
                     AEIVLTEGTKGMKGAIDKAAQLQKEIEGSVILGQFENPANPAIHRETTGPEIWEDTDGI
                     VDVFVAGIGTGGTITGVGEYLKSKNPDIRIIGVEPAGSPILSGGKPGPHGLQGIGAGFV
                     PDILNTEIYDEIIPVENQEAYETGKEIAQTEGILVGISSAAAVWAAREAAKRPEFEGKR
                     IIVLLPDTGDRYLSTPLF"
     PFAM_domain     complement(19498..20358)
                     /aSDomain="PALP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00291.27"
                     /description="Pyridoxal-phosphate dependent enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg45_104_0026"
                     /evalue="1.20E-72"
                     /label="ctg45_104"
                     /locus_tag="ctg45_104"
                     /protein_end="297"
                     /protein_start="10"
                     /score="244.9"
                     /tool="antismash"
                     /translation="LIGKTPLLELSNYQKKHGLKASVIAKLEYFNPAGSVKDRAALSMI
                     EDGEKTGRIKPGATIIEPTSGNTGIGIASIAAMKGYRAILIMPETMSVERRNLLKAYGA
                     EIVLTEGTKGMKGAIDKAAQLQKEIEGSVILGQFENPANPAIHRETTGPEIWEDTDGIV
                     DVFVAGIGTGGTITGVGEYLKSKNPDIRIIGVEPAGSPILSGGKPGPHGLQGIGAGFVP
                     DILNTEIYDEIIPVENQEAYETGKEIAQTEGILVGISSAAAVWAAREAAKRPEFEGKRI
                     IVLLPD"
ORIGIN
        1 ttaatttcat cggtttatat gtcggatccg aaaacagctc cataaacatg gctttccgct
       61 gcattaactg ttcttctgtc attattttcc tctcttttca cgttttacaa ttttatttat
      121 gttcatatta tctgcacttc caccaatggt ataacagata ttatccttaa ttcgaaaaaa
      181 acacccttgt tgctatacca caagagtgtt taatcgctac agtatattca gattcagtac
      241 caatgacaga ataaaaaata agattgctcc gtactttgta aacttctcca gttttccttc
      301 catagaacga cctttattcc tgccccagta agtatccgcc ataccaccga tagaaccaag
      361 accctgactc tttccttcct gtaacaggat gatcgctgat aaagcaatgc atataataac
      421 aaacacgatt gataatataa tccggatcat ttttccacct ccttaagtca aacaccgatt
      481 atcataccat attttttcag taaatacaat gattttttct attttaatgc cgctggccat
      541 agaattcctc aatcctgaga agttcattat atttcgccgt attctctcct ctgcagggcg
      601 ctccgcattt tatatagtcc gcccctacgg cagcggccat atctcccaga aatacttcct
      661 ccgtctcatt atcgctgttt gagaatatca ctttacttcc cattttcttt gccgcacaaa
      721 ccatattaag tgcaccagtc actgtaccag ccttttttaa ttgtacctca acaccattgg
      781 atgcaaaaaa atcgtctgaa accatcagaa gacggtgttt taacatttga tacatcctgt
      841 ttctgtcatc cggatcattc ttataaagtc cgttcattac aatgcccagc ggaaatccat
      901 ctgcaagcct taaatagtag gatatcatat ctttttgatc tctgtgaacc gggatcccat
      961 ttttcaaact ctctttgtca aagcggtaaa ttccatcctc ttttacatat agattgtccg
     1021 cattgccata gattgctgca gaaacatcgg aatcaggatc atatcccgat agcctgacgg
     1081 catccattat ataatgaaga gattcctctg aacttttcat atcagctgca aagcctccgc
     1141 tctccccaac agatgtatca tatccattta tggataatat gcgttttaat gtctggtata
     1201 tttctgttcc catccgaagt ccttctgcaa aggaaccgcg ttttaaaggg acaatcataa
     1261 tttctttaaa atcgattcct ttcacacagt ctcctccatc aatcatactc attacaggaa
     1321 cgggcattgc cggagctgat gttccgccta aataacggta gagcggaagt cccagacctg
     1381 ctcctgctgc ccttgctgct gccatggaca gagctgaaac tcctgccctg cctctgcctt
     1441 ttttatcaaa ttgctgcatt aaaagacggt cgatgttctc ctgatcagca gcattctcaa
     1501 ataaaatggc ttctgctaac cattcactta taacgtccgc ctcttcctct ccatctgctt
     1561 cattaaaaac agaaaccgtt gctctcccat gtgcaccgtt ttcaaggatc acttctgctt
     1621 ccactgccgg attcccgccg gaatcataaa gcattcttcc tcttatctgt tctatatcaa
     1681 gatcttcaag catctgattt gcctcccttt attccatcat tcctctaccg taaggattga
     1741 cgggattttt cggttccatg caggcaaata aaaaaagatg tcagaagcgg accatgagtt
     1801 tcttctgaca tctttattct atatttatgc tctcagttca ataccgaggg cctgtaaacc
     1861 attgagtatc tttttcataa cgcctgaaac ttcctgttcc tccagcgtat gatctgcagc
     1921 ccggaatgtg atggaatagg ccactgattt aaagccagcc agaatctgtg caccctcata
     1981 gatgtcaaac agctcatagc tttccaaaat tttccctccc cgctgcgcaa tcacttcctc
     2041 gatctgaccc acaagaatat ttttaggcac aaccatgctg atatctcttg ttactgccgg
     2101 atactttgca attcccgtat atttacgatc aaaacttgta aacggtatca tagaaggcat
     2161 atcaatgact gctacataag cccggtctcc gatcttatag ttatctgcaa cctccggatg
     2221 aatctctccc agataaccaa tatttactcc atcgtaaata atatctgcct gtcttcccgg
     2281 atggaggaat gtcttgcctg ccttcggatc ataatgtggt tttaatttca tgccggtttt
     2341 atcaaagaat tcctcaataa cacccttcat atcaaagaaa tcgccatctc cgtaaaagcc
     2401 cagggtaaac tgcattcttt catcaggaag ctcggttaat ggaaggctct taggcagata
     2461 gatgttagcc agctcatata aacgtacatt tttgttacgc ctgttaaaat tagtggacag
     2521 tgaatttaac atcccatgga gaggagttgt tctcataaca ctgtaatctt cacccagagg
     2581 atttaagata ttaacggtgg tgcgaagcgg actgtcctct ggaagaagca gacggtcaaa
     2641 aactttggga ctttcaaagg aatacgtcat tccctgtgaa aatccgctga attctgcaac
     2701 ctctcttgca acttcctcca ctcttaattt gtaggaaagt ttaccagttg ttgcttctcc
     2761 tgttggcagg gataccggta tcttgtcata accatagaat ctggctgttt cctctgccat
     2821 gtctgccatg cattccagat cctgacggaa tgtaggtatt atgatctccc ctgttttctc
     2881 atcatattcc agttccagac ggttataata ctcaagcatc gtctccggcg caatatctgt
     2941 tccaagaaga cggttcattc gctctggttc aaaagcaatc cgcttgcttt ctctcttttc
     3001 cggatagaca tcgatcatgc cgccgactac ttctcctgca cccagctctt caattagctg
     3061 gcatgcacgg tcaattgcag cctgtgcatt attgggatca agaccctttt caaatttacc
     3121 ggaggcatct gttcttaacc ccactttttt agaggaaaga cggatattgg ttccgtcaaa
     3181 gcaggcactt tcaaatacca tggtatgaat ttcatcggta atttttgaat tctcgcctcc
     3241 cataataccg gcgataccca cagctttctc tccgtcacgt atcatgagta cggtgctgtc
     3301 cagttttctc tcctgaccat ccagagtctg gaacagttct ccatcctctg cacatctgac
     3361 aacgatttca tggcctgata gctgatcata atcaaaggca tgcattggct gaccgtattc
     3421 ttccattaca taattggtaa tatcaacgat gttattaatt ggtctgattc cgcaggcagc
     3481 aagccttctc tgcatccaga ccggtgaagg agccagcttt aaatttttta ccattcttgc
     3541 acaatagcgg gaacaaagac ggctgtcttc gactgtcact tttaaataat cgtgaacatc
     3601 ctcactgtta cctgcagcgg ttactaccgg aggaataaat ggtttgttaa atgtagctgc
     3661 tgcctctctg gcaattccta ttacactgta acagtctacc cggtttgatg ttacttcata
     3721 ttcaaatacg gagtcatgaa ggcccaaaag ctctactgca tcagaccctg gaacagaatc
     3781 ttccggaaga atatagattc cgctttccgg agcatccgga tacatctcat ttgtaaatcc
     3841 cagttcttca atggagcaca tcattccgca ggactcaatt cctcttaatt tgcccgtttt
     3901 tatctttatt ccattttccg gaagcggacc gccgtcatgt cctccggcaa ccttccctcc
     3961 gtctaataca accggtacct tatcacctgt ttttacgttt gaagcgcctg ttacgatctg
     4021 tacggtttca ctgcctgcgt taacctggca gacaatcagt ttatccgcat cgggatggcg
     4081 tacaatcgat tgaatgtggc ctactacaat cttctctaaa tttttatcca ggcattcata
     4141 gccctcaacc ttcgttcctg tcagtgtcat ggcatccgtg tattcctgtg gtgtcacatc
     4201 caaatccggt acatatgctt taacccatga taatggtgta ttcatcaatc tatctccctt
     4261 cctgttttta gaactgcttt aagaatctga tgtcattttc atataataat ctcatgtcat
     4321 cgatctcgta tttcagcaga gcaattctct ccaagcctac tccgaaagca aagccggaat
     4381 attcgttgga atcaattccg ctcattgcaa gtacattggg gtgtaccata ccgcagccta
     4441 aaatctcgat ccagccagat cccttacaga aacggcagcc ctttcctccg cacttaaagc
     4501 aggtaacatc catttcagca ctcggctcag tgaacgggaa atgatggggg cggaacttca
     4561 cctttgtctc aggaccgaat aactctctgg caaactcagc cagtgtccct tttaagtctg
     4621 caaatgttat attcttatcg attaccagtc cttcaatctg atggaaggac ggggaatgag
     4681 ttgcatccac ttcatcggaa cggaatactc tgcctggtgc cagcatacga atcggaagtt
     4741 tccccttctc catggtcctg acctggacag gagaagtctg acttctcaaa acgatgttat
     4801 cactgatata aaacgtatcc tgttcatctc ttgccgggtg attcttcgga atgtttagtt
     4861 tttcaaagtt atagtgatca tactccactt ccggtccctc aatgacctca tatcccatgc
     4921 ctacaaagat tctctccacc tcttctaaag cgatggaatt gggatgggta tgacctactc
     4981 tgcttctctt tgcaggcaga gtgacatcaa tcacttcttt tctcaactgc tcttcccttg
     5041 cttttttcat cagtgccgcc atggcagcat ctaattttcc ctcaattgct tcacgggctt
     5101 cattgaccat ctgcccgatc ttgggtctgt cttccggagc aacgtccttc atgctcttta
     5161 gcacactggt cagttctccc ttttttccaa gataagcgac tttaatgtca cctagttttt
     5221 ccagtgcatc cgaagcttcg atctgcttta atgcttcttg tttgattctc tctaattgat
     5281 ctttcatcat gctctccttc tttgattcat tccctgatac atcaaaaaag ctccatccct
     5341 gtaaaaggga cgaagctgtg ttcgcggtac caccctgatt cctgcttcta aagcaggcgc
     5401 tcggcatacg taacgtgtaa ggacgtcatg acctacacgc ctggcagaca aatacaaccg
     5461 ccggtttcag ccatgctgct tcagtgggaa attcgatttc ttaattgaac ttaaaagggc
     5521 tttcagccgg tgaccccttc tctctgatag aaactaagaa tctacttgca ctttcatcgc
     5581 atttaattat aatataatat tgcaatcatt ataataaaac agcattaaaa tgtcaagaga
     5641 attattttaa tttgaagccg gatactacag tctttaattc ctctgcaatt cgttcctgct
     5701 tttctgacat cttagacatg tcctgtacaa ctacatatgc tttttcgatt gtgccaagga
     5761 ccatactgct gtttcctgca gtcgtctgaa cggattcgga gacattctgg attgcatcac
     5821 gcacttcctg catcacctgg ctgatgtttg cagccatctc ctccacctca ttggagattt
     5881 cttctatggt aactgcatcc ttgccatatt gctgtcctac attaacaaaa ctgtcataat
     5941 ccggagtcac cgtatctttt aagaaaacaa gcatggactg agatccatct aacatcatgg
     6001 tgaacgcatt ctgaacatct gtaatagttc cctcaatttc ctttacgatc tcagaagtat
     6061 cttttgcaag ctttccgatc tctcttgcaa caacagcaaa gcctctgccc tgttctccag
     6121 ccctcactgc ttcaattgag gcattgagtg acagtaaatt gatctgggag gccgtattgg
     6181 aaataagacg tgccatatcg ccgatccgct ccactacctt tgcgtgctgg actgccatct
     6241 gaaggtcctg ctctctttcc tgggatatca caatggcatt atcgtaagct tccctgcttt
     6301 ttttctcaat atcttttgcc cgttccatga tctctccggc catactgctg cttttttccg
     6361 tctcatttgc aagtattcct actgatgagt taacttctgc aagagacgca ttcagctcct
     6421 ccgtagctgc actggaagac atcattgcct tgtccacatc tcccatatat gttttcactt
     6481 cgctgaattg aagaagcaga tcgtttgata ctttattcag gtgaatgctg gcatctgtaa
     6541 tatctcctgc ctgatcggaa atctgttcaa tcaccccttt gttgctttgg aacatattat
     6601 tcaacgagct gctcatctgt cccagttcat cttttcgtct ggttttaaga ggctggactg
     6661 taaagtcacc ggcagcaaga gaacccgcaa acttacggac cttcttaaga cctgatgcaa
     6721 tgcttcccac ttgcagtaaa actgcaaaaa tacatagaat caatgctgca gcactcagct
     6781 tcatcaattt ctcgtttaat agaacaatgg gttcttcaag ctcagactgc ggcatcttaa
     6841 tcataataat ccagccgact cccgggaccg tatcataata gaggttataa gtcttcgttc
     6901 cctctgtgta agccgtcttt cctctgtcat ttgcaaccat ctccgctgct gcagcggaaa
     6961 gagaggcatt ctcgtcctgc ttcatattca tcgctttact gaccttatcc ccatctgcac
     7021 cgctaagata aactccttct gcagaaatca gcatggcagt tccgttcttc cccactttaa
     7081 tggacttaat cagttcatca atatcactaa gctgcatatc aaccgtcaca actccgataa
     7141 aacggctgct gctgtcataa ataggggccg cacaggtggc catcatcata tcgagagtcg
     7201 ggtcataata gggatctgta ataactggag ttttcactcc tcctgatacc gattgatagt
     7261 atgcctgatt gaaataatca taactgtcat tgctgtattc attggtctgg ataaccttat
     7321 caccgtcttt gtaccagtaa gggcccacat acttctggct ggtgtcatat acattcggct
     7381 caaaccagat accactgcca agtattaagc cgttggttga tattatatct gaaattgccc
     7441 tgccgtatgt atcaagatct gtggtctgat aggacgcact cactatatgt gaaatattca
     7501 tggccgtggt ttccaccgca tttaaatcat tattaatacc gttaacgctg gctttcaatt
     7561 ccgactccat cgtggaattg ctctgctgct caattaactg actgcttgta gattcactta
     7621 atttggccag aaaggccagg gcaagcacca gaacaggtaa aattcccaac agcatcttaa
     7681 cccctatgct tttgattccg attcttctat tcatacttta ctctcctgta attcagtctc
     7741 gaccttataa tacatatatc gacatttagt taaaaacatc atatcatacc aaggtaaatt
     7801 ttactaataa gttttgctat ttttgtgtaa gcttgattcc gttttcctat tgcaattcca
     7861 cttatgtaca tataaactgg atatcagaac ttttatacct gttaagctcc cttcctcccc
     7921 gcatctttta ctaatatcag cagtttttaa ttatactatt gatactcata ttatgcaata
     7981 tatgaatttt acatatttaa atcgtgtatt atactaattt tattatcata aaataagtac
     8041 gagaggtgac aacaatggat caagactata tcaacaaaag aattacagaa ttacgtttaa
     8101 aaaaaggagt ggcggaacat aagatgagct tggagctggg acatagcaga agttacgtgc
     8161 aaagcatttc cagcggcaga agccttccct caatggctga gtttctggca atctgtgaat
     8221 acttaagcgt aacaccgaaa gacttttttg ataatgataa tcccaacccg cccttagtca
     8281 aagacaccat agacaagctt aaaacattac cggaaagtga tctgctgctg atattgacta
     8341 ttatcaaccg gcttcagtct caatagacgg gatttttgaa aaaaaaggca gaataattca
     8401 ttgtccccgt gcatatgtac ggggattttg aggtataacc gatagtttat ggattcgtac
     8461 ttgcggcaga aacagttgtt ttaaattcat tgatttcctg aagagaaaca atggtaggta
     8521 ttgcttccag tgccctggca tatatttcgt caagatcccc ccgatttatc ataccaaaaa
     8581 aataaccata taaatcctga aaagtctgtt cgtttatcat gaaatctcat tccttcccct
     8641 ggccgaatca aagccaatac ttttaataat ctacttcatt cacgttattg tagattgtaa
     8701 tgcttttacg tattttacac aggcagctgc cccagtccag ccttttttca aacgggctgt
     8761 taaacatcac catcagcagt tttttaccta ccggatatat aatcagcatg ttataaaggt
     8821 tatcatcaag agcagtgctg ataaattcca tccaggcaaa gggaacctta ttatccaact
     8881 ctgttccatc atcgagacaa acgctcatcg gctgaaaacg ctttaaaaca agataaaatt
     8941 cctgtattac agacccaagc tgttctggct taatctccct ttccaccata ctgaaagaaa
     9001 aattaacagt accatcttca ttggttttta ttatttcagg gcgctgttca gaaaaatatt
     9061 ttctttttgc atcttccgct ttcatatctt taaataccgt aggaagaaat aggcccacct
     9121 tattatcaaa catcctcact tcacagaatt gcagtagttc tccttccaca tagatccccg
     9181 tttctatgct ggtaaaccgg ttaatccgct cgaggtgtct gtcatcaatc agtttttcat
     9241 cctcacacat gattcatcct ctctattttg ttcagtcttt atccgcgata cattggctga
     9301 tattatccac tcccatttca acaatatcag tcatcttatt atcatttgcg tatatttcca
     9361 cttttttctc ctctgcaaca gatgcccaca tcatatttaa aagcagaagt acaatcactt
     9421 ctatgacaag cagcagcctt ttaaacaatg atcctttttt accggctgtt ttatgggatc
     9481 tgtaggtgaa tcgtggtatc aggaccagtc tctcctgtaa aattctgcat tttacaattc
     9541 ctggttcacg ggatgcaaaa tcaaataaca tattctgact ttttttcaga tagtataacc
     9601 gattccaaaa atgaagatct ccgtataata tatctgtctc cagttcataa ttttttatct
     9661 cttctgtccc atcttcttta cgaatggaac agcttgccct gtattgataa taactttcat
     9721 tgtttctttt attctgcacc atcagccctc ctttcgttct aagaactatg ttacttatat
     9781 ttttattcta catggaacag aaataaattc aaccgaagtg ccaaaattgt acactttgag
     9841 tgccaaaatt tgcacacctg accgattgaa tagtgcttta gagataataa accgggtggg
     9901 ggaatttata attgtaggtg cacggaaact gctcccttag atcatcaaaa caggaaaacg
     9961 agactggcgc aaacgcacag tctcgtcttc aaatagattg ttatagctct ttcataccca
    10021 ttttactatt tttcagcact ccatatacaa gcataatgga tagcaaaagg tggcttatgg
    10081 ctagtacaac acaaatgcgg ctgttgacaa accagaagat tccgcctgcg attacttctg
    10141 caagccatag ctgtctgctt ttcaatcggt aacgtcttgt ctcctcttcg tccagaagtt
    10201 tattattatc agcaactggt gcaaagataa agattaagat tcctgatata agaaaccccg
    10261 ctattggtaa ataaagagca gccgttccaa ctatgtacat ttcaagcaaa caggtaatta
    10321 taataaggat tgccgacact acggtacaga ctccgttggt tttcgcgtga taccctccgc
    10381 aataggaccg caagggtata tagctgacaa ggaacaccaa cacaggcata ggagcgcgta
    10441 aaattactgc tatgacaaca gccacgacta tgttaataat ctggttgagt aaaacttcat
    10501 aagcgtaaag atacaatgag cgctgattat cttttaaaag attcttttta atctgccagc
    10561 tgactatgcc attggaaatc cgttgtaaca ttagaacttc ctgagactct tcgcctcttc
    10621 aggtacctct ggctggtggt gagcccagaa acaggttaca ttcatggtat aagctgcaac
    10681 cagtaatgca catgtgttca taacgttcac cattgatact tttcccttta aagcatttaa
    10741 caattttttc atcttaaatc tctccttttt tttctttaat tttataacag taatttccat
    10801 ttttcaagtc aagtgccaaa attatacacg ttgagtgcca aaatttgcac atctatcttc
    10861 tgtaaaagcc gaaatcgtta aagtcgtgat aaaaaaggcc tctttctgaa caagatttaa
    10921 tgatcctcca tacttctcag caagtgaggt aactatacct acacccaggc catgatgttt
    10981 tgaatcttct tttgtagaaa ggagtttatc accttctttt attgctttga ctttaaaact
    11041 gttttcaata cggaatatga ggaaatagtt agttcccata aatagtttta tatgtactac
    11101 acgcttttgg ggctcacatt tagaagccgc ttccaatgca ttgtcaagca ggttgccaaa
    11161 catagaaatc aggtctgagt cagatataaa atccagatta atattctttt ctataaaaat
    11221 agaaaactca actccaagtt ccttagcctt tgaaacacgt tccgacaata tggcattaaa
    11281 tacaggatta ccgctataaa taacaatatt gatctcatct tgtattttcc ctttcagttc
    11341 atctataatt tcaacaatct tttgattttc cccatttaaa gcaagcagtc gaaaactatt
    11401 aaagtacgaa tgcacatcat gcataaaaca acggtaatgg tcatttattt ttagtatgtt
    11461 ttgaaagtga tcattttcca tctctctttt cactgaataa agctctgcat attttatttt
    11521 gttcatcatg tcagtatatt tctcaagtat aataaatatt gcagcattgg aaagatataa
    11581 taaaacggct ccaccgcaca tgaaaatttg taaaactata gatttcggaa aatccatata
    11641 taaaaagctg ctggaaatag ccagagataa cacaggaacg atcagtaaat accatgaaaa
    11701 tacattatta ttcctgatat ttatcttttt aatatatttc tcaatataaa gcaaaaataa
    11761 aaagcctaca atatattcta atatcaaaaa ataaattcca cctgacgtaa accatggagg
    11821 tatgtaaatg ggaagattat aagaaaggaa ccgatataat agttcaaaaa gcacttcctt
    11881 acctcccaca aatgcaaaat aaataattgt atatgcaata ccatttgaaa aagaaatctt
    11941 aaacaaaagc agagcataaa tataacaaaa tagtggaaca gttataaaat ttaagctgac
    12001 actgccaatt gcattttcaa aaaagatcag taatgttatt acaatactaa ttatttgacg
    12061 tttttttcca aagatcttaa atggataaat agcagcaaaa aaccgaaaca tcatataaac
    12121 atctgcgccg cagaacaaaa gcctgcttac tgaaaacaaa tcatttccca tcttaattgc
    12181 catccttgta ttttgataac ataaattctt ccttcagcat atgaaattcc tgcgccttgc
    12241 tccgggtaat ctgaaacatg gtgtcaacat ctttcaggcg cagaatcttg ctggtacaat
    12301 aaaccaaata tttaaaatta ataatatagc tgtcatgagg atagccgaaa ccatactttt
    12361 taaggcgctc ataaatcgtc tccagtttat ccggaacccg gatatcaggg atttcactgc
    12421 tgtcaatttc tttaattccg taaattctaa tggagctttc agaaatatga actcttgtat
    12481 tcttcttaaa tttttctatg tatacaatat catctgcccg aagaaacagc cgttcccggt
    12541 tcacgttcgc cgtcagaagc ggtgcctgac ccagttcaat cattttatcc agagaatctc
    12601 ttatataacg gtccattaat tcatcggtca tattcttcat aatatagcgg taaggctgga
    12661 cttcaaagct gcggggagac ggttctgcaa agcctgtatt aaaaacaaga attacattat
    12721 tatccagttc cctgacccgc accgctgttt cttctccatt catttcattc atctgaacat
    12781 caagaaaaat aatagaaaat ctaatatttt taatcgctga taaaaggctg attccagaat
    12841 catattcgtg tatacggaat ttatcgcttt cgggcatatt cttaccaatt ctctctatta
    12901 aacgctctct gtcgcccata ctatcatcgc aaatagcaat ttcaaacatt ctttttcccc
    12961 tttataaatt tcttttttat tgaatatcgt atattccctc ctattttata agaaatatgc
    13021 caagaataca agaaaaggtg ccagaaaaat acaagttcat actttttcgg tacctcattt
    13081 ctgattattc aacttaatta tacggcaaac tgactgttat agagctgagc ataaaaacca
    13141 ttttctgaga gaaggtcctc atgcgttccc tgttcaatga tatggccctc cctcataacc
    13201 agtatgacat ccgcttcctt gattgtggaa agacggtgag caacaataaa gctggtgcgt
    13261 ccctccatca ttttagcaaa tgctttctgt atctttaatt cagttctggt atcgatggat
    13321 gatgtcgcct catcaagaat aagaatcggc ggaaggcaca gcatgactct tgctatgcac
    13381 aaaagctgtt tctgaccctg tgataagttt cctccgtctt ctgaaatgat tgtatcatat
    13441 ccctgcggca tgcgggaaat aaagctatgc gcatgtgctt cttttgctgc tgtgactatt
    13501 tcttcctcag atgcatccga ttttccgtag gcgatatttt ctcttatcgt cccagtcttc
    13561 agccatgttt cctgtaaaac cattccatag gaggatctta agctttctct ggtaatgtga
    13621 cgaacgtcgt ttccatccac ctttatggcc ccggcattta catcgtaaaa gcgcatgaga
    13681 aggttaatta ccgtactttt cccgcagccg gtaggaccaa caatggcaat tcgctttccc
    13741 tgtgctgcgc ataaattcat atcctcaatc aaccgtacct cctgattata ggaaaaatca
    13801 acatgttcca gaaccacctc gcctctggaa ttctttagta caaccgcctg gccgtcatcc
    13861 ggtatctctg actcttcgtc aatcagttca aatacacgtg cagctgacgc aagagcgttc
    13921 tgaagctctg ttactacgcc tgatatctca ttaaaaggtt tcgtatactg attggcataa
    13981 cttaaaaaac ttgataactg acccactgtc aaaaatccgt ttactgccgc aattgcaccg
    14041 gcgattccta cacaggcata aacaaggctg tttacaaacc gcgtagccgg attggtaatg
    14101 gaagagaaaa aggttgcctt aagtccccat acacgaagct cttcattaat ggtttcgaat
    14161 tttttctgag cctcatcttc ataagcaaag gcctttacca ccttctggtt tcccagcatc
    14221 tcctccacca gagacgtcat tactcctctt gtctgagatt gcatccggaa catactgtat
    14281 gttcttttcg ctataaaact ggccacaaac agggacagcg gggtaacaag cacaaccaga
    14341 gccccgatta acggattaat ataaaacata aaaaccagtg ttcctaaaat ggttaaaact
    14401 ccggtaaaca gctgggtgaa tcccatcagc aggccatcgg agaactgatc aatatcagca
    14461 ataattctgc tgattatatc accatgtgca tgtgaatcta tatactttaa aggaaggctt
    14521 tccagcttat taaaagcctg cgttctgatg tcctttacca cccggtaagt aatctgatta
    14581 ttgatatggc tcatgaccca ctgcgccgtt gcagtaacca gaatcactat ccccatctgt
    14641 gtcaggatca cacccattgt tttaaaatcc acttttccgg cacctgctat acaatcaata
    14701 gcgcgtccga ttaatatggg aatatacaag gtaaatacaa ctgtaagaaa cgcacaaaac
    14761 agcgaagcca ttacactcca tttgtacttt ccaatcttat ttaagattcg tttgactgta
    14821 gtcttatgcc tttttatatt catattactg cacctccttt tcagacagct gggataggca
    14881 gatttcacgg tagacctcac aggattccat taattctcca tgctttccgc agcctgccat
    14941 ccgcccatct tctaacacga caatgctgtc tgcattcttg attgtggaag ctctctggga
    15001 tactaaaaat acggtcatat ccctggtttc ctccttaatc gccttgcgga gtcttgcatc
    15061 ggtggcaaaa tccaaagcag atgcgctgtc atccaaaata agaatctggg gattttttac
    15121 aatggctctg gcaatggtaa gacgctggcg ctggcctccg gataagtttt ttccccctgc
    15181 ctgtatcaga aagtcaagtc cttccccttt ttcttccaca aattcctttg cctgggcaat
    15241 agtaagtgcc cggtaaatgt cttcatcaga ggcatccttt ttcccccact gcatgttttc
    15301 ccgaatactt cctttaaaaa gaaccgcctt ttggggaaca atacctacca tctctctcag
    15361 ctggcccagc ggatattccc tgacatcgat accttccact ctgacgctcc cctgagatac
    15421 atcataaaat cttggaatta cgttcaccag tgtggatttt cctgatcccg tccctcctat
    15481 aattccgatg gtctcacctt ttttcgcgca aaatccaatt cccctcagag attcagactt
    15541 tgcaccctga taaaaaaggc ttacctgatt aaattccacc ttgggtgaat ctgttttccc
    15601 ctttacctcg ttatggtttg tgtctttaat gcctggttcc atggaaaaca cggaactgat
    15661 ccggttggca caggccagag ctttggatat ggtgataatt aagttggcaa gcttcaccag
    15721 ctcaaccagt atctgagaca tgtaatttac aagagccact acctgaccct gagtgatatt
    15781 ccctgtctga acccgatttg caccggtgtt aatgagtaca atgattgcaa ggtttataat
    15841 tacataagta aaaggattca tcaatgcgga tatcttacct acaaatacct ggagtttcac
    15901 aagcatgcca ttctcttcat cgaacctgcg tacttcatca ttctgacggt taaatgcacg
    15961 gatcacacgg acgccgccca gattttctct tgctgccagt aagacccggt ccagctgctt
    16021 ttgtactttt ttatatagag gcatactaaa aagcataata ccgaatacta caactgaaag
    16081 taccggtatg gaaaccgcaa atatcagagc tgcctttata tcgatggtaa atgccataat
    16141 cattgcgccg aaaacaacaa acggtgagcg cagaaacagg cgcagaaata aattcacacc
    16201 ggactggacc tgattcacat cactggtcat tcgggtaatg agagtggccg ttcctatggt
    16261 atcaatttcc tgaaaagaca gagtgttaat atgggaaaac agatcatttc ttaatgaagt
    16321 accaaaacct gccgctgcct ttgccgcaaa gtactgtgct gttatggaac aggtaagacc
    16381 gataatgcct aacagaacca gcagtccacc catggacaga atataagtca catcatggtt
    16441 tttgattcca atgtcaatga ttgctgccat taccagaggc acaagaagtt caaaactggc
    16501 ttccagaagc ttgaacaatg gtcccagtat gctttcccgc ttataattac tcaaatactt
    16561 aaggagcttt ttcatttttc ttaatcctcc cgcaaataat actttttaag aataatgcat
    16621 tgtattatta taccattttg atataataat acaagtataa aatgaaatca gatagaatag
    16681 aggatgtacc agatgattcc aattaattca aaacagttat actattttac cgtcgtctca
    16741 gagaccggaa gttttactgc agctgcaaaa aaactgggga tttctcagcc gcctttaagc
    16801 aagcagatta tgcttctgga ggaagagatg ggagtgaagc ttcttgagcg cagatcgaaa
    16861 aaggcagagc ttacagaagc aggcacatat ttatatttta aggcaaaaga tattttatcc
    16921 atgatgggga ctgtatcaga tgatttaaag cattttccat cttctgccag aggtgtgctg
    16981 aagctgggga ccatttcttc atccggaact gtacttctgg attttttaaa gaatttcaca
    17041 tcagctcacc caggtgtccg gtttgaagta acagaaggca atacctatga actcctggag
    17101 aaaatgaaaa atggacttgt agaatgttcc attatacgaa caccttttaa tccggagggt
    17161 cttaaatgtg tctacggtaa gaaagaaccc attatggcag tgggtaatcc cgcatttttc
    17221 ccggagttta cagggaataa ggtaagtctt acagagttga aggggaagcc attaatttat
    17281 taccgcagat ttgattccat catttctctg gcatttcaaa acagcgggat caaaccggat
    17341 atcttttgca ggaatgacga tgcaaggacc tgtctacaat gggcaaaagc aggaatggga
    17401 attgctctgg taccccaatc catcagcctc accctggggc aggaaaatct gttattccgg
    17461 gaaattgatt cttccgatac cgttacccag atagccgctg tatacaaaaa aaatggctat
    17521 gtctcaaaca tagccaggga atttgtaacc agttttggcg atcagtccaa ttgattaatc
    17581 aaaaaggctc aactgggtaa tctggtaatt tttcttgtac gcgtgaatta tatccggcat
    17641 tttataaaga atccggtttc ggctgcactc ttcagaaaac acctgccata atttacgtgc
    17701 tcttggactg gtgcactggt aattatttcc ataacgcttc atatactgct ctgccaggtt
    17761 atctccagga aacagctccc ctaatcggtc ataataccat tctctctgat tgttccgcag
    17821 cgtgacacca aaagccggat agataaaatc agcgccggct tctttcgctg cagctataat
    17881 agaactgata ttgtcttcat tatcctccag aaaagggagg acaggcatca gaaggatccc
    17941 tgcaaacagc ccctggtctt taagggccgc aatcagtgac agccggtcgg atggtctgga
    18001 aaccctgggt tcaattttag acgccagatt atcatcactt gtagtaaccg taacctttag
    18061 aataacagga gaatgatctg ctatactttt cagtatatca atatcccttt gaagcaaagt
    18121 actttttgta gcaatggctg ccccaaaacc aaaggcatca atcaattcca gggcatgtct
    18181 ggtaagctta agttcatttt ccagtggatt gtatggatca ctcattgctc ctgttcccac
    18241 cactcctgtt tttacttttc ttctcagatc atcccgtatg atccgaagtg catcctcctt
    18301 gacacgtacg gtatcaaaat gatcaattct gtaacagtct gaacggctgt cacagtaaat
    18361 acagccatga ctgcagcctc tgtatatatt catattataa tcaatcccaa accagccgga
    18421 ggtctttgtt tttgttacaa ttgtttttgc cgggatgtat tccatgataa ttctccctct
    18481 ttttatactt ttttcactga acagagaatc ccttgatatt ttctaagtgc catgataata
    18541 tgcttatacg agataggaag ggaagcgttc attatgattc gttttttatt gcgctgcaaa
    18601 cagatatatg acaaatatac gaaagatgaa atgactgtct atgcagcaca ggcttcatat
    18661 tttaccataa ttgctgcttt tccgtttatg atgctgttac ttgctatgat tcagtttatt
    18721 ccttctatta caaaagcgaa tttactgcag cttctggtca cggtgattcc cagcacgttg
    18781 gagattgaca gcgttatcgt taacgtgatt gaagatctct acaccaagtc acctgcagca
    18841 atcttatctg tgaccgccat tgctgcgatc tggtctgctt caaagggtat gcttagcatt
    18901 gaacggggat taaaccgggt tttcgggcag gaaaaaaaac gtgggtattt catgacccgt
    18961 gtcgtctgtg ccggttatac ggttgtgttt attataatct gtaccctgac acttgtacta
    19021 cttgtactgg gcagttccat acaggctttt atgaaccgac attttcccat tctggccgag
    19081 attacccagc atgttatcag tttccgtact atgctcttat ttattcttac tttatgtttt
    19141 gccatgcttt atacctatgt acccgaaaag aagcagcatt ttaccagaca actgccagga
    19201 gccgtctttt ccacactggg gtggattgcc ttctcctttg ccttttctat ttactttagc
    19261 aatttcagca attattccgt tatgtacggc agcctgactg ccattgttct catcatgctg
    19321 tggctgtatt cctgcatctg cattctgttt ttcggagctg aaatcaatta ctattattca
    19381 gaaaacagga aggaataaat gaacgaaaga ccagagatcc tttaaagatc cctggtcttc
    19441 ttaatccatc agctgacttt aagaaaacag cggcgtggat aaatatctgt ctcctgtatc
    19501 cggaagaaga acgatgattc tttttccttc gaattccggc cgttttgcag cttccctggc
    19561 tgcccatact gctgcagcag aggatattcc cacaaggatt ccttccgtct gtgcgatctc
    19621 tttgcccgtc tcataagctt cctgattctc tacaggtatt atttcatcat agatctctgt
    19681 gtttagtata tcagggacga aaccagctcc aattccctgg agtccgtgag gtcccggctt
    19741 tcctccggaa agaatggggg atcctgctgg ttctactccg ataatccgga tatcaggatt
    19801 cttactcttt agatattccc caactccggt tatggtacca cccgttccga tccctgccac
    19861 aaatacatca actatcccat cagtatcttc ccagatttca ggccctgtgg tttcccgatg
    19921 tattgccgga ttggccggat tctcaaactg ccctaaaatg acggaacctt cgatctcttt
    19981 ttgcagctgg gcagctttat caattgcacc tttcatccct tttgttcctt cggtaagtac
    20041 aatctcagct ccatatgctt ttaaaagatt ccttcgttcc acactcatgg tttcaggcat
    20101 gatgagaatt gcacgatacc ctttcatggc agcgatactg gcaattccaa taccagtatt
    20161 tccagatgtg ggttcaatga tagttgcccc cggctttatt ctgccggttt tttctccatc
    20221 ctcaatcatg gacagcgctg ctctgtcttt tacactgcca gccgggttaa aatattccag
    20281 ttttgcaatg acagatgcct taagtccgtg tttcttctgg taattggaaa gttccagcaa
    20341 aggagttttt ccaatcagtt cccgggcact ttttttaatg ttttccataa taaacctctt
    20401 ttcttacacg tttcctgatt tcattttatc tgcaggtaat taatattatg ataaaccata
    20461 aagcttacgg tacttttctt tcaggtaatc gatgaagtat tccggagtaa agtcctctcc
    20521 tgtcgctgcc tttattaact cacggcttgt cttcatctta ccatattgat gaatatggct
    20581 tcgcagatat tctttgatca cgtccagctt cccatctctt aaaaggccat taaaatccat
    20641 ctcctttttc atatggaaat acagctgtgc tccaaatgca ttcccaaggg catatgatgg
    20701 gaaatatccg aacaatccct gagaccagtg gatatcctgc aggactcctt ct
//
