LOCUS       NZ_KB946334.1          21442 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KB946334.1 Enterococcus caccae ATCC BAA-1240 acvJM-supercont1.3,
            whole genome shotgun sequence.
ACCESSION   NZ_KB946334
VERSION     NZ_KB946334.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:18:41
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 170798
            Orig. end    :: 192240
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21442
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[180798:182240]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11442
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21442
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21442
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(210..1739)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257:Alpha-glucosidase (Score: 476.4; E-value:
                     2.1e-144)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_163"
                     /sec_met_domain="Alpha-amylase (E-value: 1.7e-104,
                     bitscore: 344.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LDYLKKLGISAIWLSPVYRSPNDDNGYDISDYEQIMAEFGTMSDM
                     EQLIREAQQREIKIIMDLVVNHTSDEHPWFIESRSSKENPYRDFYVWRQESIGGGAPND
                     LESTFLGSAWQLDELSGEYYLHLFSQKQPDLNWENQNVRTAIYNMMNFWIDKGIGGFRM
                     DVIDLVGKIPDQKITGNGPKLHDYLQEMNAQTFGGKDLLTVGETWGATPEIAKLYSNPE
                     RNELSMVFQFEHIGLDEEPGKSKWDLRPLQITELKEVFSKWQTELGDQGWNSLFWNNHD
                     LPRIVSRWGNDSAYRVQSAKMLAISLHMLKGTPYIYQGEEIGMTNRVIHDITEVEDIES
                     KNMYADRIQKGYAKEDILVSINAKGRDNARTPMQWDDTENAGFTTGTPWLTVNENYHEI
                     NAKQALADTNSVFYTYQKLIKLRKNCPLIVWGSFELIEDTATDVFAYYRHYREQSWLIV
                     CNFSDQEQIFSLDKFAVETIITNTEKDYTELFDRTLEPYEAFVVDVSNYPS"
     PFAM_domain     complement(240..449)
                     /aSDomain="Malt_amylase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16657.7"
                     /description="Maltogenic Amylase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_163_0002"
                     /evalue="2.70E-08"
                     /label="ctg3_163"
                     /locus_tag="ctg3_163"
                     /protein_end="500"
                     /protein_start="430"
                     /score="33.9"
                     /tool="antismash"
                     /translation="GSFELIEDTATDVFAYYRHYREQSWLIVCNFSDQEQIFSLDKFAV
                     ETIITNTEKDYTELFDRTLEPYEAF"
     PFAM_domain     complement(759..1739)
                     /aSDomain="Alpha-amylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00128.26"
                     /description="Alpha amylase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_163_0001"
                     /evalue="4.20E-123"
                     /label="ctg3_163"
                     /locus_tag="ctg3_163"
                     /protein_end="327"
                     /protein_start="0"
                     /score="411.3"
                     /tool="antismash"
                     /translation="LDYLKKLGISAIWLSPVYRSPNDDNGYDISDYEQIMAEFGTMSDM
                     EQLIREAQQREIKIIMDLVVNHTSDEHPWFIESRSSKENPYRDFYVWRQESIGGGAPND
                     LESTFLGSAWQLDELSGEYYLHLFSQKQPDLNWENQNVRTAIYNMMNFWIDKGIGGFRM
                     DVIDLVGKIPDQKITGNGPKLHDYLQEMNAQTFGGKDLLTVGETWGATPEIAKLYSNPE
                     RNELSMVFQFEHIGLDEEPGKSKWDLRPLQITELKEVFSKWQTELGDQGWNSLFWNNHD
                     LPRIVSRWGNDSAYRVQSAKMLAISLHMLKGTPYIYQGEEIGMTNR"
     CDS             complement(1783..3648)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1257:Alpha-glucosidase (Score: 279.1; E-value:
                     1.3e-84)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_164"
                     /sec_met_domain="Alpha-amylase (E-value: 1.9e-79, bitscore:
                     262.0, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTAAIHHQPESEFAYLYTSDKMHIRLRTGREDIKSVELLNGDPY
                     QLEHSEWFNLTIPMEKYLSTTTHDYWTVETSAPFRRLSYAFKIEGMDGTMLFYGDHGFF
                     PYQETTLKTASNYFKLPYFHEADRFKAPQWVKETIWYQIFPERFANGDPTNDPTGTLPW
                     GSKAHPDRNDFFGGDLQGVLDHLDHLVDLGINGIYFCPIFQAASNHKYDTIDYFEIDSA
                     FGDKVLFKKLVQECHKRGIRVMLDAVFNHMGDFSPQWQDVIKNGEQSAYANWFHIHKFP
                     VTYTPTANFEFSDNITYDTFAFTPHMPKLNTANKEVQDYLLEIARYWIAEFDIDAWRLD
                     VANEVDHRFWRKFHDVCTEAKPDIYILGEIWHSSQAWLQGDEFHGVMNYAFTDAILSYF
                     VYKTISLSKLVSELNHQLMLYREQTNQIMFNVLDSHDTPRLLTIAQNDKELMKQVLAFT
                     YLQKGVPCLYYGDEYAMDGAGDPDCRKCMIWESEQQDLDMYEFVKTLIAFRKKYQPLLS
                     EGKLRWQEINEQTGLIDFAYEHEGKMIRSIFNTGQTPIYLEKETILFSTNMHSLDKNII
                     ELAPYGFAVSVDNIERIEKNDLSGNKHSLVAGSRRLSNLSTEFSR"
     PFAM_domain     complement(2206..3120)
                     /aSDomain="Alpha-amylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00128.26"
                     /description="Alpha amylase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_164_0004"
                     /evalue="8.90E-71"
                     /label="ctg3_164"
                     /locus_tag="ctg3_164"
                     /protein_end="481"
                     /protein_start="176"
                     /score="239.3"
                     /tool="antismash"
                     /translation="GDLQGVLDHLDHLVDLGINGIYFCPIFQAASNHKYDTIDYFEIDS
                     AFGDKVLFKKLVQECHKRGIRVMLDAVFNHMGDFSPQWQDVIKNGEQSAYANWFHIHKF
                     PVTYTPTANFEFSDNITYDTFAFTPHMPKLNTANKEVQDYLLEIARYWIAEFDIDAWRL
                     DVANEVDHRFWRKFHDVCTEAKPDIYILGEIWHSSQAWLQGDEFHGVMNYAFTDAILSY
                     FVYKTISLSKLVSELNHQLMLYREQTNQIMFNVLDSHDTPRLLTIAQNDKELMKQVLAF
                     TYLQKGVPCLYYGDEYAMDGAGDP"
     PFAM_domain     complement(3277..3648)
                     /aSDomain="Alpha-amylase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02903.16"
                     /description="Alpha amylase, N-terminal ig-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_164_0003"
                     /evalue="2.40E-38"
                     /label="ctg3_164"
                     /locus_tag="ctg3_164"
                     /protein_end="124"
                     /protein_start="0"
                     /score="131.1"
                     /tool="antismash"
                     /translation="MNTAAIHHQPESEFAYLYTSDKMHIRLRTGREDIKSVELLNGDPY
                     QLEHSEWFNLTIPMEKYLSTTTHDYWTVETSAPFRRLSYAFKIEGMDGTMLFYGDHGFF
                     PYQETTLKTASNYFKLPYFH"
     CDS             4022..5257
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 191; E-value:
                     7e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_165"
                     /transl_table=11
                     /translation="MKRNMKKLLTLGVTMTAAAFALAACGGGSSDKKASDGNENASIKL
                     WVDVAFVDTYKPLVEQFEKEHKDWKVTIKPSESATAQENLKKDPSAAADVFMMPHDQLG
                     QMVDAGIIYANTKYEDSVKENSTESAVEAATYDGKLYGYPYGVESQILYYNKEKLAEGD
                     VKSWETLTAKGKLGANFGEAGANYIFTPLFMSNGDELYGKNGEDIKGTNFNNDKGVQVL
                     KWIRAQKDNAGVVQSNADALSNLGNGKIDAFLSGPWSKLDVEKALGDKFAVAPYPTVDL
                     GNGEVQQKAFLGVKLFGVNASTKSPVAAMALADFLTNKENQLTVFEKNGTVPANKEAQA
                     DGKVTSDKVAEAVMTMSDADHSVVMPKLPAMVSFWGPADAVINDTYNGKIAEDQYLPKL
                     DKLVQDTSKSDK"
     PFAM_domain     4193..5065
                     /aSDomain="SBP_bac_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13416.8"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_165_0005"
                     /evalue="4.10E-48"
                     /label="ctg3_165"
                     /locus_tag="ctg3_165"
                     /protein_end="348"
                     /protein_start="57"
                     /score="164.7"
                     /tool="antismash"
                     /translation="LVEQFEKEHKDWKVTIKPSESATAQENLKKDPSAAADVFMMPHDQ
                     LGQMVDAGIIYANTKYEDSVKENSTESAVEAATYDGKLYGYPYGVESQILYYNKEKLAE
                     GDVKSWETLTAKGKLGANFGEAGANYIFTPLFMSNGDELYGKNGEDIKGTNFNNDKGVQ
                     VLKWIRAQKDNAGVVQSNADALSNLGNGKIDAFLSGPWSKLDVEKALGDKFAVAPYPTV
                     DLGNGEVQQKAFLGVKLFGVNASTKSPVAAMALADFLTNKENQLTVFEKNGTVPANKEA
                     QADGKVTSDK"
     CDS             5370..6725
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 185.2; E-value:
                     2.7e-56)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_166"
                     /transl_table=11
                     /translation="MKLKAKADGPISFRELFKKGDTSIKLSYIFMGMANILNGQIIKGL
                     AFLALQIGFVAWLVVNGFHALSMLQSLGTKAQGWVMDESLGIEVQQPGDNSMLLLLFGI
                     AAIILILLFIFMYIVNLRSARKIFTLKQAGQSLPTLKEDLNSLLNEKFYITLMSIPLLG
                     VLAFTILPLLYMISIAFTSYDHNHLPPKNLFHWVGFANFSNVITGDIAGTFFPVLTWTL
                     IWAVLATATTFFFGILLALLINAKGVKGKKVWRTIFVITMAVPQFVSLLLMANLFNGSG
                     PVNAMLQNWGLIDQPIPFLTDALLAKVTVIFVNMWVGIPVTMLVATGIITNLPTDQIEA
                     AEIDGANKFQIFRNITFPQILFVMAPSLIQQFIGNINNFNVIFLLTGGQPANSNFHSAG
                     ETDLLVTWLYKLTVTAADYNLASVIGIIIFVLSAVFSLFAYTRSSSFKTEGA"
     PFAM_domain     6069..6683
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_166_0006"
                     /evalue="6.30E-22"
                     /label="ctg3_166"
                     /locus_tag="ctg3_166"
                     /protein_end="438"
                     /protein_start="233"
                     /score="78.3"
                     /tool="antismash"
                     /translation="FFGILLALLINAKGVKGKKVWRTIFVITMAVPQFVSLLLMANLFN
                     GSGPVNAMLQNWGLIDQPIPFLTDALLAKVTVIFVNMWVGIPVTMLVATGIITNLPTDQ
                     IEAAEIDGANKFQIFRNITFPQILFVMAPSLIQQFIGNINNFNVIFLLTGGQPANSNFH
                     SAGETDLLVTWLYKLTVTAADYNLASVIGIIIFVLSAVFSLF"
     CDS             6734..7573
                     /gene_functions="transport (smcogs) SMCOG1069:putative ABC
                     transporter permease protein (Score: 232.5; E-value:
                     1e-70)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_167"
                     /transl_table=11
                     /translation="MKSKKRKNLVLHYTLLTILSIVWIFPIVWIVLTSFRSEGGAFVTY
                     FIPKQFTFENYKMLLTSSTYPFVQWFLNTLFVAVCSCILSTLITIAMAYSLSRLRFRAR
                     KPFLKLALVLNMFPGFMSMIAVYYILKAMNLTGSLLALILVYSSGAALGFYIAKGFFDT
                     IPMALDESAMIDGASKFEIFTKITLPLSKPIIVYTALMAFMAPWMDFIFAKIILGDNVN
                     KYTVAIGLFTMQTKDKIDQYFMAFTAGCVLIAVPITLLFIFMQKYYVEGITSGSVKG"
     PFAM_domain     6992..7543
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_167_0007"
                     /evalue="1.30E-15"
                     /label="ctg3_167"
                     /locus_tag="ctg3_167"
                     /protein_end="270"
                     /protein_start="86"
                     /score="57.7"
                     /tool="antismash"
                     /translation="LITIAMAYSLSRLRFRARKPFLKLALVLNMFPGFMSMIAVYYILK
                     AMNLTGSLLALILVYSSGAALGFYIAKGFFDTIPMALDESAMIDGASKFEIFTKITLPL
                     SKPIIVYTALMAFMAPWMDFIFAKIILGDNVNKYTVAIGLFTMQTKDKIDQYFMAFTAG
                     CVLIAVPITLLFIFMQKYYVE"
     CDS             complement(7607..8242)
                     /locus_tag="ctg3_168"
                     /transl_table=11
                     /translation="MQITIFGGSGFIGQKLAEELVTRGHNVTSISRKGKPADLSSSWSE
                     KVHWFHSDILNDTYWHQVVQKSDWVIDTIGILFEHPRKKITYDRFILTPVQLILDYLNT
                     HNPSAHFLFISANSAPFPLRKYMDAKLQAEQLIKENPQHHVIIYPSLVVDKQRYFSVIS
                     AAMIRSLKGIPGIKKLVRSYDPISREKLAIEISNVIEGKTSAYTQRQT"
     PFAM_domain     complement(7892..8236)
                     /aSDomain="Epimerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01370.23"
                     /description="NAD dependent epimerase/dehydratase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_168_0008"
                     /evalue="2.80E-08"
                     /label="ctg3_168"
                     /locus_tag="ctg3_168"
                     /protein_end="117"
                     /protein_start="2"
                     /score="33.6"
                     /tool="antismash"
                     /translation="ITIFGGSGFIGQKLAEELVTRGHNVTSISRKGKPADLSSSWSEKV
                     HWFHSDILNDTYWHQVVQKSDWVIDTIGILFEHPRKKITYDRFILTPVQLILDYLNTHN
                     PSAHFLFISAN"
     CDS             complement(8824..9672)
                     /locus_tag="ctg3_169"
                     /transl_table=11
                     /translation="MINEGSSFKNIRQSRKITQKDICKQKISRTTLSKFENNKIMLSMA
                     NFNYLLNSIDVSFEEFNFIENGYSYKDKEQIIYFFNKIFSNSDLKYLDNLITLCDNYLD
                     DNFSKSIKCIRSTLYMLKHIADSTDSKLNCQSKLYAADVWNELSKVDSWTILDIKIINC
                     CLHFFDPNTYPLISKQLIKSLDKYKNFSNIILLETSIYLNLTLLFSLQNDKKSALLFSK
                     KALDKSFQSKRIDYISISLIRYGLLSNQKGKINDGLNILKLLNDESLYKVVKEEVDTFV
                     I"
     PFAM_domain     complement(9490..9648)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_169_0009"
                     /evalue="6.30E-05"
                     /label="ctg3_169"
                     /locus_tag="ctg3_169"
                     /protein_end="61"
                     /protein_start="8"
                     /score="23.1"
                     /tool="antismash"
                     /translation="KNIRQSRKITQKDICKQKISRTTLSKFENNKIMLSMANFNYLLNS
                     IDVSFEEF"
     CDS             10001..11116
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SPASM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_170"
                     /sec_met_domain="PF04055 (E-value: 1.7e-23, bitscore: 78.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.9e-12, bitscore: 42.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.9e-13, bitscore:
                     44.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.4e-12, bitscore: 40.5,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGYYYKPILVDVCVTNRCNLNCDYCSAESGPFASKKGELTIQKL
                     SELFQEMDKIKVPRVALTGGEPFIREDIIEILYEFDKYNFTKVLNTNGNLIRDKQALAL
                     SKLNLDRICVTLDGSNPEVHDSSRGKGSFKKAIEGIRQLQKYNLPVSTLFTLGKHNVND
                     LINTIKLNDKLNINFMSVMVICPTGRANDGSVLADKENWYPVFLELSERIKNKEFKVNF
                     KIVPPNESDIFWTHYFPLEYYNRLDLLQVWGVELESYKNRVDRDISCQAGIKACSISHK
                     GDVYGCDLMNGIDELVAGNINESNLMEIWNNSSVFRKFREMNFNDLSGKCSICPHTWCG
                     GGCRCSALELDGSLLGSDSSCFYKPMEEIQC"
     PFAM_domain     10040..10504
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_170_0010"
                     /evalue="6.10E-22"
                     /label="ctg3_170"
                     /locus_tag="ctg3_170"
                     /protein_end="168"
                     /protein_start="13"
                     /score="78.8"
                     /tool="antismash"
                     /translation="CVTNRCNLNCDYCSAESGPFASKKGELTIQKLSELFQEMDKIKVP
                     RVALTGGEPFIREDIIEILYEFDKYNFTKVLNTNGNLIRDKQALALSKLNLDRICVTLD
                     GSNPEVHDSSRGKGSFKKAIEGIRQLQKYNLPVSTLFTLGKHNVNDLINTI"
     PFAM_domain     10805..11005
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_170_0011"
                     /evalue="3.20E-10"
                     /label="ctg3_170"
                     /locus_tag="ctg3_170"
                     /protein_end="335"
                     /protein_start="268"
                     /score="40.4"
                     /tool="antismash"
                     /translation="CQAGIKACSISHKGDVYGCDLMNGIDELVAGNINESNLMEIWNNS
                     SVFRKFREMNFNDLSGKCSICP"
     aSDomain        10805..11077
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_170_0001"
                     /evalue="3.70E-12"
                     /identifier="TIGR04085"
                     /label="ctg3_170"
                     /locus_tag="ctg3_170"
                     /protein_end="359"
                     /protein_start="268"
                     /score="44.5"
                     /tool="antismash"
                     /translation="CQAGIKACSISHKGDVYGCDLMNGIDELVAGNINESNLMEIWNNS
                     SVFRKFREMNFNDLSGKCSICPHTWCGGGCRCSALELDGSLLGSDS"
     CDS             11080..11442
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Streptide_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_171"
                     /sec_met_domain="PF05402 (E-value: 2.4e-08, bitscore: 28.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 6.9e-09,
                     bitscore: 30.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="Streptide_RRE (E-value: 7.3e-12, bitscore:
                     40.1, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLQADGGDTMLAKNFYIDGKKKLYFEKDEEMNFLTFDPIRLSYF
                     EVSNIGAEILYCISKKMKLEHIVALITDEYDISREGCISEVIEFLNYIPIQDIIYTNLI
                     QSDVYLYLEPFNKEVI"
     PFAM_domain     11206..11352
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_171_0012"
                     /evalue="5.20E-06"
                     /label="ctg3_171"
                     /locus_tag="ctg3_171"
                     /protein_end="91"
                     /protein_start="42"
                     /score="26.7"
                     /tool="antismash"
                     /translation="SYFEVSNIGAEILYCISKKMKLEHIVALITDEYDISREGCISEVI
                     EFLN"
     CDS             11444..12745
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 148.5; E-value: 4.1e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_172"
                     /transl_table=11
                     /translation="MRKRIFIDINKFSLPLIFSQLITTIIGQKAFSIAARLGTDNLIAM
                     NTIDNLIYSVTGVLGVISVAFSMLSSKSLGEKDTDKFKKLVSSVMHANVIIGSLFFFII
                     LFFSKIFISAIYKFSDELLSVATTYLYSMSFYVLLTLITFTLTNLLKVEKKTNYILTIS
                     IISSLIQVLLSYIFINGIGNFSGLGVFGAGIALNITLLITILCYLIIVRATFFSCLKLK
                     PIYIKDILIRSIPLGIQELLEGIIFLIFFDAMIARLDTMSLSVYSIISQALVYLKLPMF
                     MYGNAVTIFASEYFGEKNKNKIIVVKRISTYMSIFFYVLIGIGIYLMIVPFSNLFTFDD
                     KLINETTKMILPLFFLVSPIILYEINKYILQVIENGKFVVKWTLIINIISMGTILMFHF
                     YGSLDLYYIYMVYFGNYLILSALFELKFKKVCIR"
     PFAM_domain     11486..11971
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_172_0013"
                     /evalue="2.20E-15"
                     /label="ctg3_172"
                     /locus_tag="ctg3_172"
                     /protein_end="176"
                     /protein_start="14"
                     /score="56.8"
                     /tool="antismash"
                     /translation="PLIFSQLITTIIGQKAFSIAARLGTDNLIAMNTIDNLIYSVTGVL
                     GVISVAFSMLSSKSLGEKDTDKFKKLVSSVMHANVIIGSLFFFIILFFSKIFISAIYKF
                     SDELLSVATTYLYSMSFYVLLTLITFTLTNLLKVEKKTNYILTISIISSLIQVLLSYI"
     PFAM_domain     12146..12613
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_172_0014"
                     /evalue="1.20E-12"
                     /label="ctg3_172"
                     /locus_tag="ctg3_172"
                     /protein_end="390"
                     /protein_start="234"
                     /score="47.8"
                     /tool="antismash"
                     /translation="PLGIQELLEGIIFLIFFDAMIARLDTMSLSVYSIISQALVYLKLP
                     MFMYGNAVTIFASEYFGEKNKNKIIVVKRISTYMSIFFYVLIGIGIYLMIVPFSNLFTF
                     DDKLINETTKMILPLFFLVSPIILYEINKYILQVIENGKFVVKWTLIINIIS"
     CDS             complement(13026..13847)
                     /locus_tag="ctg3_173"
                     /transl_table=11
                     /translation="MKVLTLNTHSWLENEPLEKLHQLATQITQEEYALIALQEVNQRID
                     SLPVVSPYNFHPSEKQLPIHEDNFAYLLVQLLKEQGHDYHWSWAYNHIGYSTYHEGVAL
                     LSKQPIHPKTVVVSEEQNPNDYRTRVLLIGQTELAGKPITAVCCHYSWWLETGGFSYEW
                     KQTEQALQNHSSPLLLMGDFNNPASVAKTGYDLVLTSSLQLQDSFLAADQKVGEHTVEK
                     AIDGWGENQEKLRIDYIFASQELSVSSYQIVFDGKSTPVISDHFGVSAIIQ"
     PFAM_domain     complement(13053..13790)
                     /aSDomain="Exo_endo_phos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03372.25"
                     /description="Endonuclease/Exonuclease/phosphatase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_173_0015"
                     /evalue="8.80E-11"
                     /label="ctg3_173"
                     /locus_tag="ctg3_173"
                     /protein_end="265"
                     /protein_start="19"
                     /score="41.9"
                     /tool="antismash"
                     /translation="LHQLATQITQEEYALIALQEVNQRIDSLPVVSPYNFHPSEKQLPI
                     HEDNFAYLLVQLLKEQGHDYHWSWAYNHIGYSTYHEGVALLSKQPIHPKTVVVSEEQNP
                     NDYRTRVLLIGQTELAGKPITAVCCHYSWWLETGGFSYEWKQTEQALQNHSSPLLLMGD
                     FNNPASVAKTGYDLVLTSSLQLQDSFLAADQKVGEHTVEKAIDGWGENQEKLRIDYIFA
                     SQELSVSSYQIVFDGKSTPVISDH"
     CDS             complement(13933..16110)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1145:Glucose-specific phosphotransferase enzyme IIA
                     (Score: 524.3; E-value: 4.9e-159)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_174"
                     /transl_table=11
                     /translation="MKKLLSFEFWQKFGKALMVVIAVMPAAGLMISIGKTIPLINPDWA
                     ALTTTGGVIENIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLSFILINRITGSIFG
                     VTSDMLADDKAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAFNKYYN
                     YRKLPDALSFFNGKRFVPFVVILWSTIVAILLAIIWPSIQAGINNFGLWIAQSQDTAPI
                     LAPFLYGTLERLLLPFGLHHMLTIPINYTQLGGTYEILSGAQAGTQVFGQDPLWLAWAT
                     DLVNLKGAGDTSQYNYVLANWTPARFKVGQMIGASGILMGMTLAMYRNVDPDKRSNYKS
                     MYLSAALAVFLTGVTEPLEFMFMFAAVPLYVVYAIIQGAAFAMADIVSLRVHSFGNIEL
                     LTRTPLAIKAGLGGDLLNFVLCTIAFGVLTYFIANFMIKKFNFATPGRNGNYDNNETQT
                     NATTSNTQNTDGIDPQIIDIIHLLGGKENIVDVDACMTRLRVSVTDKSKVGTEDAWKKA
                     GAMGLIVKDNGVQAVYGPKADVLKSDIQDLLDSGAAIPTPKQTETIAITASNSDYLGLT
                     KTIVPVANGEVIAIEQVNDPVFSQKMMGDGFAVNPTNETIYAPIDGVISSIFPSKHALG
                     IQTEEGIEVLVHMGLDTIEMKESAFTILVTEGQKVTAGEKIATADLEKIKAAGKQTTMI
                     VVFTNGEKINAFHLDKVGNQDPGTAIGRLDI"
     PFAM_domain     complement(14005..14379)
                     /aSDomain="PTS_EIIA_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00358.22"
                     /description="phosphoenolpyruvate-dependent sugar
                     phosphotransferase system, EIIA 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_174_0018"
                     /evalue="2.20E-47"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="702"
                     /protein_start="577"
                     /score="160.1"
                     /tool="antismash"
                     /translation="TIVPVANGEVIAIEQVNDPVFSQKMMGDGFAVNPTNETIYAPIDG
                     VISSIFPSKHALGIQTEEGIEVLVHMGLDTIEMKESAFTILVTEGQKVTAGEKIATADL
                     EKIKAAGKQTTMIVVFTNGEK"
     aSDomain        complement(14014..14367)
                     /aSDomain="TIGR00830"
                     /aSTool="tigrfam"
                     /description="PTBA: PTS system, glucose subfamily, IIA
                     component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_174_0003"
                     /evalue="1.40E-40"
                     /identifier="TIGR00830"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="699"
                     /protein_start="581"
                     /score="136.0"
                     /tool="antismash"
                     /translation="VANGEVIAIEQVNDPVFSQKMMGDGFAVNPTNETIYAPIDGVISS
                     IFPSKHALGIQTEEGIEVLVHMGLDTIEMKESAFTILVTEGQKVTAGEKIATADLEKIK
                     AAGKQTTMIVVFTN"
     aSDomain        complement(14461..16104)
                     /aSDomain="TIGR02003"
                     /aSTool="tigrfam"
                     /description="PTS-II-BC-unk1: PTS system, IIBC component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_174_0002"
                     /evalue="3.40E-291"
                     /identifier="TIGR02003"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="550"
                     /protein_start="2"
                     /score="964.6"
                     /tool="antismash"
                     /translation="KLLSFEFWQKFGKALMVVIAVMPAAGLMISIGKTIPLINPDWAAL
                     TTTGGVIENIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLSFILINRITGSIFGVT
                     SDMLADDKAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAFNKYYNYR
                     KLPDALSFFNGKRFVPFVVILWSTIVAILLAIIWPSIQAGINNFGLWIAQSQDTAPILA
                     PFLYGTLERLLLPFGLHHMLTIPINYTQLGGTYEILSGAQAGTQVFGQDPLWLAWATDL
                     VNLKGAGDTSQYNYVLANWTPARFKVGQMIGASGILMGMTLAMYRNVDPDKRSNYKSMY
                     LSAALAVFLTGVTEPLEFMFMFAAVPLYVVYAIIQGAAFAMADIVSLRVHSFGNIELLT
                     RTPLAIKAGLGGDLLNFVLCTIAFGVLTYFIANFMIKKFNFATPGRNGNYDNNETQTNA
                     TTSNTQNTDGIDPQIIDIIHLLGGKENIVDVDACMTRLRVSVTDKSKVGTEDAWKKAGA
                     MGLIVKDNGVQAVYGPKADVLKSDIQDLLDS"
     aSDomain        complement(14509..14799)
                     /aSDomain="TIGR00826"
                     /aSTool="tigrfam"
                     /description="EIIB_glc: PTS system, glucose-like IIB
                     component"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_174_0004"
                     /evalue="1.60E-18"
                     /identifier="TIGR00826"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="534"
                     /protein_start="437"
                     /score="64.8"
                     /tool="antismash"
                     /translation="KKFNFATPGRNGNYDNNETQTNATTSNTQNTDGIDPQIIDIIHLL
                     GGKENIVDVDACMTRLRVSVTDKSKVGTEDAWKKAGAMGLIVKDNGVQAVYG"
     PFAM_domain     complement(14587..14682)
                     /aSDomain="PTS_EIIB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00367.22"
                     /description="phosphotransferase system, EIIB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_174_0017"
                     /evalue="2.60E-14"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="508"
                     /protein_start="476"
                     /score="52.5"
                     /tool="antismash"
                     /translation="DIIHLLGGKENIVDVDACMTRLRVSVTDKSKV"
     PFAM_domain     complement(14977..16071)
                     /aSDomain="PTS_EIIC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02378.20"
                     /description="Phosphotransferase system, EIIC"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_174_0016"
                     /evalue="1.80E-53"
                     /label="ctg3_174"
                     /locus_tag="ctg3_174"
                     /protein_end="378"
                     /protein_start="13"
                     /score="181.7"
                     /tool="antismash"
                     /translation="GKALMVVIAVMPAAGLMISIGKTIPLINPDWAALTTTGGVIENIG
                     WGVIGNLHILFALAIGGSWAKERAGGAFAAGLSFILINRITGSIFGVTSDMLADDKAFT
                     HTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAFNKYYNYRKLPDALSFFNG
                     KRFVPFVVILWSTIVAILLAIIWPSIQAGINNFGLWIAQSQDTAPILAPFLYGTLERLL
                     LPFGLHHMLTIPINYTQLGGTYEILSGAQAGTQVFGQDPLWLAWATDLVNLKGAGDTSQ
                     YNYVLANWTPARFKVGQMIGASGILMGMTLAMYRNVDPDKRSNYKSMYLSAALAVFLTG
                     VTEPLEFMFMFAAVPLYVVYAIIQG"
     CDS             16354..18633
                     /locus_tag="ctg3_175"
                     /transl_table=11
                     /translation="MNHLFEIDPWKIATHQLERNERRLQESLTSMGNGYMGMRGNFEEH
                     YTGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINAVNFIAMDIFVNGEVLDLGIQ
                     EPKDFYLELDMHNGLLTRTFILEKEEARVKFRFERFLSIVQQELAVIRVTAEVLEGTAD
                     IQIISKIDGDVRNEDSNYDEMFWEAQQSGFEEAIGFLTTKTIPNPFGIEQFSVTAAMKH
                     VTEAKAGVAETEPLKVQQSFQANLQASESITLEKQVIVLTSRDIPEAEQQEKAVQLLNQ
                     TTKTFAELLNEQNAAWRKRWELADVVIEGDDAAQQGIRFNLFQLFTTYYGEDERLNIGP
                     KGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRYNQLEQAKHNARQQGLAGA
                     LYPMVTFTGIECHNEWEITFEEIHRNGAIAYAIYNYVNYTGDNEYLKNEGLQVLTEIAR
                     FWADRVHFSKRTGKYMIHGVTGPNEYENNINNNWYTNTIATWVLQYTLENYDKYQAETP
                     VKISKEEQVHWQEIIENMYYPFDEELGVFVQHDTFLDKDLMPRTALTSADLPLNQHWSW
                     DRILRSCFIKQADVLQGIYFFGERFSRAEKERNFLFYEPMTVHESSLSPSVHAVLAAEL
                     GMEEKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLAIVQGFAQMKTADEQLSFAP
                     FLPSTWTSYAFHVNYRDRLLYVTVDQDNVRLQLVSGAELPLTLYGNKLVLADELVIEME
                     KVNPHV"
     PFAM_domain     16393..17145
                     /aSDomain="Glyco_hydro_65N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03636.17"
                     /description="Glycosyl hydrolase family 65, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_175_0019"
                     /evalue="8.80E-58"
                     /label="ctg3_175"
                     /locus_tag="ctg3_175"
                     /protein_end="264"
                     /protein_start="13"
                     /score="195.7"
                     /tool="antismash"
                     /translation="THQLERNERRLQESLTSMGNGYMGMRGNFEEHYTGDHHQGTYLAG
                     VWYPDKTRVGWWKNGYPEYFGKVINAVNFIAMDIFVNGEVLDLGIQEPKDFYLELDMHN
                     GLLTRTFILEKEEARVKFRFERFLSIVQQELAVIRVTAEVLEGTADIQIISKIDGDVRN
                     EDSNYDEMFWEAQQSGFEEAIGFLTTKTIPNPFGIEQFSVTAAMKHVTEAKAGVAETEP
                     LKVQQSFQANLQASESITLEKQVIVLTSR"
     PFAM_domain     17308..18423
                     /aSDomain="Glyco_hydro_65m"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03632.17"
                     /description="Glycosyl hydrolase family 65 central
                     catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_175_0020"
                     /evalue="3.50E-154"
                     /label="ctg3_175"
                     /locus_tag="ctg3_175"
                     /protein_end="690"
                     /protein_start="318"
                     /score="513.4"
                     /tool="antismash"
                     /translation="RFNLFQLFTTYYGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPL
                     YLALAKPEVTKNLLKYRYNQLEQAKHNARQQGLAGALYPMVTFTGIECHNEWEITFEEI
                     HRNGAIAYAIYNYVNYTGDNEYLKNEGLQVLTEIARFWADRVHFSKRTGKYMIHGVTGP
                     NEYENNINNNWYTNTIATWVLQYTLENYDKYQAETPVKISKEEQVHWQEIIENMYYPFD
                     EELGVFVQHDTFLDKDLMPRTALTSADLPLNQHWSWDRILRSCFIKQADVLQGIYFFGE
                     RFSRAEKERNFLFYEPMTVHESSLSPSVHAVLAAELGMEEKAVEMYQRTARLDLDNYNN
                     DTEDGLHITSMTGSWLAIVQGFAQMKTADEQL"
     PFAM_domain     18433..18585
                     /aSDomain="Glyco_hydro_65C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03633.17"
                     /description="Glycosyl hydrolase family 65, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_175_0021"
                     /evalue="1.40E-14"
                     /label="ctg3_175"
                     /locus_tag="ctg3_175"
                     /protein_end="744"
                     /protein_start="693"
                     /score="53.8"
                     /tool="antismash"
                     /translation="PFLPSTWTSYAFHVNYRDRLLYVTVDQDNVRLQLVSGAELPLTLY
                     GNKLVL"
     CDS             18626..19300
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 135.5; E-value: 3.4e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_176"
                     /transl_table=11
                     /translation="MFKGVLFDLDGVLTDTAEYHYQAWQRLGKEIGITIDRTFNEELKG
                     VSREDSLTLLLAHGGKTNDFTSAEFAELAKRKNEYYVEMIQQVSPKDVYPGILDLLKNL
                     KKQGIKISLASASKNGPFLLEKMALMPYFDGIADPSAVAKGKPDPEIFQLAAKNVGLQA
                     AECIGIEDAKAGIQAIIASHALPIGVGRSEDLGANIALVSSTKELTFEFLLSVWQTAKA
                     DS"
     aSDomain        18629..19174
                     /aSDomain="TIGR02009"
                     /aSTool="tigrfam"
                     /description="PGMB-YQAB-SF: beta-phosphoglucomutase family
                     hydrolase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_176_0006"
                     /evalue="3.00E-57"
                     /identifier="TIGR02009"
                     /label="ctg3_176"
                     /locus_tag="ctg3_176"
                     /protein_end="183"
                     /protein_start="1"
                     /score="191.8"
                     /tool="antismash"
                     /translation="FKGVLFDLDGVLTDTAEYHYQAWQRLGKEIGITIDRTFNEELKGV
                     SREDSLTLLLAHGGKTNDFTSAEFAELAKRKNEYYVEMIQQVSPKDVYPGILDLLKNLK
                     KQGIKISLASASKNGPFLLEKMALMPYFDGIADPSAVAKGKPDPEIFQLAAKNVGLQAA
                     ECIGIEDAKAGIQAIIASH"
     aSDomain        18629..19195
                     /aSDomain="TIGR01990"
                     /aSTool="tigrfam"
                     /description="bPGM: beta-phosphoglucomutase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_176_0005"
                     /evalue="1.70E-79"
                     /identifier="TIGR01990"
                     /label="ctg3_176"
                     /locus_tag="ctg3_176"
                     /protein_end="190"
                     /protein_start="1"
                     /score="264.1"
                     /tool="antismash"
                     /translation="FKGVLFDLDGVLTDTAEYHYQAWQRLGKEIGITIDRTFNEELKGV
                     SREDSLTLLLAHGGKTNDFTSAEFAELAKRKNEYYVEMIQQVSPKDVYPGILDLLKNLK
                     KQGIKISLASASKNGPFLLEKMALMPYFDGIADPSAVAKGKPDPEIFQLAAKNVGLQAA
                     ECIGIEDAKAGIQAIIASHALPIGVG"
     PFAM_domain     18638..19159
                     /aSDomain="HAD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13419.8"
                     /description="Haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_176_0022"
                     /evalue="1.90E-22"
                     /label="ctg3_176"
                     /locus_tag="ctg3_176"
                     /protein_end="178"
                     /protein_start="4"
                     /score="80.3"
                     /tool="antismash"
                     /translation="VLFDLDGVLTDTAEYHYQAWQRLGKEIGITIDRTFNEELKGVSRE
                     DSLTLLLAHGGKTNDFTSAEFAELAKRKNEYYVEMIQQVSPKDVYPGILDLLKNLKKQG
                     IKISLASASKNGPFLLEKMALMPYFDGIADPSAVAKGKPDPEIFQLAAKNVGLQAAECI
                     GIEDAKAGIQA"
     aSDomain        18854..19177
                     /aSDomain="TIGR01509"
                     /aSTool="tigrfam"
                     /description="HAD-SF-IA-v3: HAD hydrolase, family IA,
                     variant 3"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_176_0007"
                     /evalue="4.00E-15"
                     /identifier="TIGR01509"
                     /label="ctg3_176"
                     /locus_tag="ctg3_176"
                     /protein_end="184"
                     /protein_start="76"
                     /score="54.3"
                     /tool="antismash"
                     /translation="KNEYYVEMIQQVSPKDVYPGILDLLKNLKKQGIKISLASASKNGP
                     FLLEKMALMPYFDGIADPSAVAKGKPDPEIFQLAAKNVGLQAAECIGIEDAKAGIQAII
                     ASHA"
     CDS             19435..20445
                     /gene_functions="regulatory (smcogs) SMCOG1078:LacI family
                     transcription regulator (Score: 250.7; E-value: 3.8e-76)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg3_177"
                     /transl_table=11
                     /translation="MTITVKDVAKKAGVATSTVSRVINDHSSISDATKKKVYKVMEEMG
                     YVPNIAARNLGKRSSGAVGVILPPLDSRERMGNPFYLEIIESINDEARKHSMTTAIATA
                     QSFETLLENVQLMHRQKQVDGFILLYSDKEDPVIDYLFENQVPFSLIGQPYTNEDKVIY
                     VDNDNQLLGKHATDYLIENGHRNILFITNTTHENVYYERYFGYQKAMMLANLPVLPSVD
                     MEKPEDYVAFEQLLKETKATAAVVIDDIFAMRMIQLAQMYGYRVPDDFSVISFNNSIYA
                     TLVHPYLTSIDIDIAELGRMGMQKLIESLQEKEATGVRMVIPHKLIKRETVLSLK"
     PFAM_domain     19444..19581
                     /aSDomain="LacI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00356.23"
                     /description="Bacterial regulatory proteins, lacI family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_177_0023"
                     /evalue="5.80E-20"
                     /label="ctg3_177"
                     /locus_tag="ctg3_177"
                     /protein_end="49"
                     /protein_start="3"
                     /score="70.9"
                     /tool="antismash"
                     /translation="TVKDVAKKAGVATSTVSRVINDHSSISDATKKKVYKVMEEMGYVP
                     N"
     PFAM_domain     19960..20430
                     /aSDomain="Peripla_BP_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13377.8"
                     /description="Periplasmic binding protein-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_177_0024"
                     /evalue="4.90E-28"
                     /label="ctg3_177"
                     /locus_tag="ctg3_177"
                     /protein_end="332"
                     /protein_start="175"
                     /score="98.6"
                     /tool="antismash"
                     /translation="TDYLIENGHRNILFITNTTHENVYYERYFGYQKAMMLANLPVLPS
                     VDMEKPEDYVAFEQLLKETKATAAVVIDDIFAMRMIQLAQMYGYRVPDDFSVISFNNSI
                     YATLVHPYLTSIDIDIAELGRMGMQKLIESLQEKEATGVRMVIPHKLIKRETV"
ORIGIN
        1 gaataccatt gagatcacca attccatcat gattactgtc tttaaaactg cgtggataaa
       61 tttgatatcc tacagcattt tcccaccaat tttgttgtgc tgttgtattc acttcttttg
      121 tttgaatagc tgagttaggc atattttttc ctcctaaatt taagcgcata gctagagagt
      181 gttaaaaact gaaaggttaa cgcttgaatc tagcttggat aattagatac atcaacaaca
      241 aaagcttcgt aaggctctaa cgttctgtca aaaagctccg tatagtcttt ttcagtattt
      301 gtaataatcg tttctactgc gaatttatct agcgaaaaaa tttgctcttg atcagaaaaa
      361 ttacaaacaa ttagccagct ttgttctcga tagtggcgat aataagcaaa aacatccgtt
      421 gcagtatctt cgattaattc aaaactgccc caaacgatca atggacaatt tttgcggagt
      481 ttaatcagct tttgatacgt ataaaagaca gagtttgtat ctgctaatgc ttgtttagcg
      541 ttgatttcat gatagttttc gttaacggta agccaaggtg ttccagttgt gaaaccggca
      601 ttttcagtat catcccattg cataggtgtg cgagcgttat cgcgaccttt ggcgttgata
      661 gatactagaa tatcttcttt tgcataccct ttttggattc gatcggcata catattttta
      721 ctttcaatat cttcaacttc tgtgatatcg tggatcacac gattggtcat cccgatttct
      781 tcaccttgat aaatataagg tgtccctttt aacatgtgaa gtgaaattgc caacatttta
      841 gcgctttgta cacggtaagc actatcgtta ccccatcttg aaacgattcg gggcaaatca
      901 tgattgttcc agaataaaga attccaaccc tgatcaccaa gttctgtttg ccattttgaa
      961 aaaacttctt ttagttcagt tatttgcaaa gggcgtagat cccatttgct ctttccaggt
     1021 tcctcatcta atccaatgtg ttcaaattga aagaccattg aaagttcgtt tctttctgga
     1081 ttagagtaca gcttagcgat ttcaggtgtg gctccccacg tttccccaac ggttaataaa
     1141 tcttttcctc caaatgtttg ggcgttcatt tcttgtagat agtcatgcaa ttttgggcca
     1201 tttccggtta ttttttgatc gggtattttc ccaacaagat cgatcacatc catacgaaaa
     1261 ccgccaattc ctttatcgat ccaaaagttc atcatgttgt agatagctgt tcgcacattt
     1321 tgattttccc aattcaaatc cggctgtttt tgactaaata gatgcagata atattcacca
     1381 gaaagctcgt ctaattgcca tgcagaacct agaaaagttg attctaagtc atttggggct
     1441 cctcctccaa tgctttcctg ccgccaaaca tagaaatcgc ggtagggatt ttcttttgag
     1501 gagcgggatt caatgaacca ggggtgttca tcgctagtgt gattgaccac gagatccata
     1561 atgattttta tctctctttg ttgggcttct cggatcagtt gttccatatc gctcatagtg
     1621 ccaaactcgg ccatgatttg ctcgtaatcg ctaatgtcat aaccgttgtc gtcgtttggt
     1681 gaacggtaga cagggctgag ccaaattgca ctgattccta actttttcaa ataatccaac
     1741 cgttgaatga ttccagctaa atcaccaata ccatcaccgt tactatcttg aaaactccgt
     1801 ggataaattt gataaacgac ggcttcctgc caccaatgag tgtttgtttc ctgataggtc
     1861 atttttttca atcctttcta tgttgtctac tgatacagca aaaccgtatg gtgcaagttc
     1921 aataatattt ttatctaatg agtgcatatt ggtcgaaaat aaaatcgttt ctttttcaag
     1981 ataaatgggg gtctggcccg tgttaaaaat actgcggatc atttttcctt cgtgttcata
     2041 ggcaaagtcg atgagcccgg tttgttcatt gatttcctgc cagcgtagtt ttccttctga
     2101 taagagtggt tgatattttt ttctaaaggc aatcaaggtc ttaacgaatt catacatgtc
     2161 taaatcttgt tgctctgatt cccaaatcat acatttacga caatcaggat caccggctcc
     2221 gtccatagcg tattcatctc cgtagtatag acaaggcacc cctttttgca agtaagtaaa
     2281 tgctaaaact tgtttcatca gctctttgtc attttgagcg attgtcagca aacgaggggt
     2341 atcgtgagag tcaagtacat taaacatgat ttgattggtt tgttcacgat aaagcattaa
     2401 ctgatgattt agttcggaaa cgagtttgct taatgagatc gttttataga caaaatagga
     2461 aagaattgca tcagtaaatg cgtaattcat gacgccgtga aattcatcgc cttgaagcca
     2521 tgcttgagaa gaatgccaaa tttcgccgag aatataaatg tctggtttag cttctgtaca
     2581 gacatcgtgg aattttcgcc aaaaacgatg atctacttca tttgctacat ctaatcgcca
     2641 agcatcaata tcgaattctg cgatccagta acgggcaatc tctaataaat aatcttgcac
     2701 ttccttgttt gctgtattta atttaggcat atgtggagtg aaagcgaatg tatcgtacgt
     2761 aatattatcg gagaattcaa aattcgctgt tggtgtgtaa gtaactggga atttatgaat
     2821 atggaaccag ttggcataag ctgactgttc tccatttttg attacatctt gccactgagg
     2881 tgaaaagtca cccatatgat tgaaaacagc atccaacatg acgcggatac cgcgtttgtg
     2941 gcattcttgt acaagtttct taaagagaac cttatcgcca aaagcggaat caatctcaaa
     3001 ataatcaatc gtatcatatt tgtgattgct agcggcttgg aagattgggc agaaataaat
     3061 cccgttgatt ccaagatcca ccaagtggtc caaatgatct aaaacacctt gtaaatcacc
     3121 accaaaaaag tcattccgat caggatgcgc tttacttccc caaggtaaag tccctgttgg
     3181 atcattcgtt gggtcgccat tggcaaaacg ttcagggaaa atttgatacc aaattgtttc
     3241 ttttacccac tgaggtgctt tgaaacggtc tgcttcatgg aaatacggta atttaaaata
     3301 attactggcg gtttttaacg tggtttcttg atatgggaaa aaaccgtgat cgccataaaa
     3361 cagcatagtc ccatccatgc cttctatctt aaaagcgtag cttaggcgtc taaaaggtgc
     3421 agaagtttcg acagtccaat aatcgtgagt ggtagtagat aagtattttt ccattggaat
     3481 tgttaagttg aaccactcgc tgtgctcaag ctggtatgga tcaccattca gtagttcgac
     3541 acttttgatg tcctctcgtc ccgttcttaa tcgaatgtgc attttgtctg atgtatataa
     3601 ataagcaaat tcactttctg gttgatggtg gattgctgca gtattcatct aatttgtccc
     3661 cctatagtcg ccttagtatg tttctggccg tacgtttcta aaaacaactc atattatgcc
     3721 atataagaaa aacgttttca atgtattttt cgcaaacgat tgcattttat tttgttagaa
     3781 caattatttt ttcgagtgtt gaaaggaaat agctggataa taagcctttt tttatttaaa
     3841 agactttatt tggtgtataa tcactgtttt tatgtttagt cagtagattg gtttaatcat
     3901 atcatttgta gtctagtaaa acatttttat gctttttaaa gatttctctt gacaatttac
     3961 gcaaacgatt gcacaatgta ggagaataga acagcaaaat aattcctagg aggaacaaaa
     4021 gatgaaaaga aacatgaaaa agcttttgac attaggggta acaatgacag cggcggcatt
     4081 tgcgcttgcg gcttgtggcg gaggttcatc agataaaaaa gcttctgatg gaaatgaaaa
     4141 cgcttctata aaattgtggg tggatgtagc gtttgtagat acgtataaac cgttagtaga
     4201 acaatttgaa aaagaacaca aagattggaa agttacgatc aagccaagtg agtctgccac
     4261 agcccaagag aatctaaaaa aagatcctag tgccgcagca gatgttttca tgatgcctca
     4321 tgatcaatta ggtcaaatgg tggatgctgg aattatttat gcgaatacga aatacgaaga
     4381 tagcgttaaa gagaatagta ctgaaagtgc tgtggaagct gcaacttatg atggtaaatt
     4441 atacggttac ccatatggtg ttgaatcaca aattttatat tataacaaag aaaagttagc
     4501 tgaaggcgat gtgaagagtt gggaaacgtt gacggctaaa ggcaaattag gtgcgaactt
     4561 tggagaagct ggcgcaaact atattttcac accattattc atgtcaaatg gcgatgaatt
     4621 atatggtaaa aacggtgaag atatcaaagg aacgaatttt aacaatgata aaggtgtgca
     4681 agtcttaaaa tggattcgtg cccaaaaaga taacgctggt gtcgttcaat cgaatgcgga
     4741 tgcactttct aacttaggca atggtaaaat cgatgctttc ttatctggtc cgtggtctaa
     4801 actagatgta gaaaaagcgt taggtgataa gtttgcagta gcgccatacc caacagttga
     4861 tttaggcaat ggtgaagtac agcaaaaagc atttttaggc gtgaaattat tcggagtgaa
     4921 tgcttcaact aaaagtccag tagcagcaat ggctttggct gatttcttaa caaataagga
     4981 aaatcaatta actgtttttg aaaaaaatgg cacagtgcca gcaaataaag aggcacaagc
     5041 agatggtaaa gtgacatctg ataaagtagc agaagcggtt atgacaatga gtgatgctga
     5101 tcattcggtt gtaatgccaa aacttccagc gatggtttct ttctggggac cagctgatgc
     5161 ggtaatcaat gatacctata atggcaaaat cgctgaagat caatacttac caaaattgga
     5221 taaattagtt caagatacta gtaaatccga taaataatcg ataaattgca gcaaaaaata
     5281 gaggctgagt agtcagggag aaactgaaaa agttttaact tggcttctca gacctcttga
     5341 tttcaaagaa gaacaggaag tgaaatgcta tgaaactaaa agcaaaagcc gatgggccga
     5401 tttcttttag agagttgttt aaaaagggag atacctcgat caagctttct tatattttta
     5461 tgggaatggc gaatatcttg aacggacaaa tcatcaaagg gctggcattt ttagcgttgc
     5521 agataggatt tgtggcgtgg ttagtcgtaa atggttttca tgcgttgtcg atgctgcaat
     5581 cattggggac gaaagctcaa ggttgggtca tggatgagtc gctgggaatc gaagtgcaac
     5641 agccaggtga caattcgatg ttactgttgt tgtttggaat cgctgcaatt attcttattt
     5701 tactttttat ttttatgtat atcgtgaacc taagaagtgc gcgtaaaatt tttacgttaa
     5761 aacaagctgg gcagtctcta ccgacattga aagaagattt aaatagtttg ttgaatgaaa
     5821 aattttatat cacactgatg agtattccgt tattgggtgt attagcgttt acgattttgc
     5881 cattgctgta tatgatttct attgcattta ctagctatga tcataatcat ttaccgccta
     5941 aaaatttatt tcattgggtt ggttttgcta attttagcaa tgtgattaca ggtgatattg
     6001 ctggaacttt cttcccggtg cttacttgga cgttgatttg ggcagtttta gcgaccgcga
     6061 caacgttttt cttcggcatt ctattagcat tattaattaa cgctaaaggg gtgaaaggga
     6121 aaaaagtttg gcggacgatt ttcgtcatca cgatggctgt tccgcaattt gtcagtttat
     6181 tattgatggc taacttattt aatggttcag gacccgttaa cgcgatgctg caaaattggg
     6241 gactgattga tcaaccgatt ccttttttaa cagatgctct acttgcgaaa gtcacggtta
     6301 tctttgttaa tatgtgggtt gggattcctg taacgatgtt ggttgcaacg ggaatcatta
     6361 cgaatctacc gacagatcaa atagaagcag cggaaatcga tggtgcgaat aaatttcaaa
     6421 tttttagaaa tattaccttc ccgcagattt tatttgtaat ggcacctagt ttgatccaac
     6481 agtttattgg aaatatcaat aacttcaatg tgattttctt gttgactggc ggacaaccag
     6541 cgaatagtaa ttttcactct gcaggtgaga cggacttgtt ggtaacatgg ttgtataaat
     6601 taacggtaac tgcagctgat tataatctcg catctgtgat tgggatcatt atctttgttc
     6661 tttcagcggt cttctcgtta tttgcttata cgcgaagcag ttcatttaaa acggaagggg
     6721 cgtaaacaag catatgaaat cgaaaaaaag aaagaattta gttttgcatt atacgttatt
     6781 gacgatttta tcgattgtct ggatctttcc aatcgtttgg attgttttga ctagttttag
     6841 aagtgagggc ggagcgtttg taacgtattt tattccgaaa cagtttactt ttgaaaacta
     6901 taaaatgttg ttgacaagct ccacgtatcc ttttgtgcaa tggtttttaa atacgttgtt
     6961 tgtagcagtt tgcagttgta ttttatcaac attgatcaca attgcgatgg cgtattcttt
     7021 aagtcgtttg cgctttagag cacgtaaacc gtttttgaaa ttagcactag tgttgaatat
     7081 gtttccaggc tttatgagta tgatcgctgt gtattacatt ttgaaggcga tgaatttaac
     7141 aggtagtttg ttggcattga ttttagtgta ttcatctggt gcagcgttag gtttttatat
     7201 tgcaaaggga ttctttgata cgatcccgat ggcgttggat gaatctgcga tgatcgatgg
     7261 ggcgagtaag tttgagattt tcacgaaaat cacattgccg ttgagtaaac cgatcattgt
     7321 gtatacagcg ttgatggctt ttatggcgcc atggatggat ttcatttttg ctaaaatcat
     7381 tttaggcgat aatgttaata aatatacagt ggcaatcggt ctgttcacaa tgcagacgaa
     7441 agataaaatc gatcaatact ttatggcatt tacagcaggt tgtgtgctga ttgcggttcc
     7501 gatcacgtta ttgtttatct ttatgcaaaa gtactatgta gaagggatta cgagtggttc
     7561 agttaaaggg taaaagaaaa agcatttcct tagcggagat gcttttttat gtctgccttt
     7621 gagtgtaggc ggaggttttt ccttcaatca cgttagaaat ttctattgct agcttttctc
     7681 tggaaatagg atcatagctg cggacaagtt ttttgattcc agggattcct ttaagtgagc
     7741 ggatcattgc tgcgctaata acggaaaaat accgttgttt gtctacaact agacttgggt
     7801 aaatgataac gtgatgttgc ggattttctt tgatgagttg ttctgcctgg agcttagcat
     7861 ccatgtattt tcttaaagga aatggagcgc tattggctga tataaacaag aaatgagccg
     7921 atggattgtg tgtgttcaga taatctaaaa tcaattgaac aggtgtcaaa ataaagcggt
     7981 cataggtgat ttttttgcgt ggatgttcaa aaagaatacc tattgtatca atgacccaat
     8041 cagatttctg gacaacttga tgccagtatg tgtcgtttaa gatatcggaa tgaaaccagt
     8101 ggactttttc tgaccaagaa cttgataggt ccgcaggttt tccttttcgt gaaatgctgg
     8161 ttacattatg ccctctggtg actagttctt cggcaagctt ttgtccgata aagccgcttc
     8221 cgccaaaaat cgttatttgc atcttttctt cctgctttct tgaaattatt atgataaatc
     8281 cgtatgatag ctagtttatc attatctatc ggaaagtacg ttaaggaatg cttgagggag
     8341 agaatgaaga attactatcc gttgtattta gtgtttctat tttcttagtg gttattttag
     8401 gagcagcctg ttctttgcga ttgttggcat agttttattg acttcaaaaa ttgagttgtt
     8461 gaatcgatca ttttagagat cccaaaaaag accgtttttg gaaggtatta ttgagcgaaa
     8521 ggcatctaaa aaaatcaagg gaacgtttat tgaagaacta ttgctgggtg caaaactatt
     8581 ataggctaag taattttagc ctataaatga aacaatgagt tagatagtga tgtggggtat
     8641 tgtaacaata gcatttaggg gtgggaggac cgctcccttt tttgcctatc ccaaaacatt
     8701 ctttcttaag acaaacaaaa aacacctacg aattatagat gtttctgtct gttttcaatt
     8761 agcattcaat aaacattaaa cttgttctta attggcataa atcccattaa aaagttagaa
     8821 aagttaaatg acgaaagtgt ctacttcctc tttaacaact ttatataaag actcatcatt
     8881 taaaagtttt aatatgttta atccatcatt aatttttcct ttttgattag acagaaggcc
     8941 atacctgatt aatgatatag aaatataatc aattctttta ctctggaagg atttatctag
     9001 tgctttttta gaaaaaagca gagcagattt tttatcattt tgtagtgaaa aaaggagtgt
     9061 taaatttaga tatatagatg tttctaataa tataatatta gaaaaatttt tgtacttatc
     9121 taacgattta attaattgtt tgcttataag aggataggta tttggatcaa aaaagtgtag
     9181 acagcaatta attattttta tatctaaaat ggtccaagaa tcaactttag atagttcatt
     9241 ccaaacatct gcagcgtata gtttagattg gcaatttaat ttactgtcgg ttgaatctgc
     9301 gatgtgtttt aacatataca atgtactgcg gatacactta attgacttac tgaaattgtc
     9361 atctaggtag ttatcacaaa gtgtaattaa attgtcaaga tattttaagt cactattgga
     9421 gaaaatctta ttaaagaaat atataatttg ttctttatcc ttataagagt atccgttttc
     9481 aataaaatta aactcctcaa atgaaacatc aatagaatta agtaaataat taaaattagc
     9541 catagacaac attattttat tattttcaaa ctttgataaa gtggtcctgg aaattttttg
     9601 tttacaaata tctttttggg ttatctttct tgactgtcta atatttttaa atgaacttcc
     9661 ctcattaatc ataatgtagc ctccttttaa acataagatg tgattatagt ttacatcata
     9721 agttatgaga ttcacaatag ggtattcttt gtaagaagga ggataaaaga tcatgagaaa
     9781 attatttaga attgttttat ttgcatcaat tttttggata gttggtggtt agtttatcct
     9841 ctaaaaaaat agtggaggtt tttctatgga aaagaaaaaa gaatttaaaa agattcgttt
     9901 tgctaatgtt gctgcttggg gtaaacatta atttttagca aaaagaaaga tgagaagttt
     9961 ggattttcat ctttcttttt tttaaaagga ggaataaaaa atgaggggat attattataa
    10021 acctatacta gtagatgtat gtgtaactaa tagatgtaat ttaaattgtg attattgttc
    10081 agctgaatct ggcccatttg ctagtaaaaa aggagaatta acaatacaaa aattgtctga
    10141 gttattccaa gaaatggata aaattaaagt tccaagggtt gctttaacag gtggagaacc
    10201 atttataaga gaagatatta ttgaaatttt gtatgaattc gataaataca atttcacaaa
    10261 agttttgaac actaacggaa atttaattag agataaacag gcattagcgt tatcaaagtt
    10321 aaatctggat agaatttgtg ttacattaga tggaagcaat cccgaagtac atgatagctc
    10381 tagaggtaaa ggttcattta aaaaagcaat tgaaggtata agacaattac aaaaatataa
    10441 tctaccggta tcaacgctat ttaccctagg taaacataat gttaatgatt taattaatac
    10501 cataaaatta aatgataaac tgaatataaa ttttatgtct gtcatggtta tttgtccaac
    10561 tggtagggct aatgatggaa gtgtattagc agacaaagaa aattggtatc ctgtattttt
    10621 agaattatca gaaagaataa aaaataaaga atttaaagtt aattttaaaa tagtacctcc
    10681 aaatgaaagt gatatatttt ggacgcatta ttttcctttg gaatactata atcgattaga
    10741 tttattgcaa gtttggggtg tggaactaga gtcatacaaa aatagagtag atagagatat
    10801 ttcttgtcaa gctggaatca aagcatgttc catttctcat aaaggagatg tttatggatg
    10861 tgatttgatg aatgggattg atgaattagt tgcaggaaat ataaatgaaa gtaatttaat
    10921 ggagatatgg aataactcat ctgtatttag aaaatttaga gaaatgaatt ttaatgattt
    10981 atctggtaaa tgttctatct gtcctcatac atggtgtggt ggtggttgca gatgtagtgc
    11041 attagagtta gatggttctt tattaggatc tgactcatca tgcttttaca agccgatgga
    11101 ggagatacaa tgttagctaa aaatttttat attgatggta agaaaaaact gtattttgaa
    11161 aaagatgaag aaatgaattt cttaactttt gatccaataa gattatccta ttttgaagtt
    11221 agcaatattg gtgcagaaat attatattgt atttctaaaa aaatgaaatt agaacatata
    11281 gtagcgttaa taacagatga atatgatatt agtagagaag gttgcatttc tgaagtgata
    11341 gaatttttaa attatatacc tattcaagat ataatttata ctaacttgat tcaatcagat
    11401 gtgtatctat atttagaacc ttttaataag gaagttatat aatatgagaa aaagaatttt
    11461 tatagatatt aataaattct cattaccatt aatattttca caactaataa cgactattat
    11521 agggcagaaa gcattctcta tagctgcgag attaggaact gataatttaa ttgctatgaa
    11581 tacaattgat aacttaattt attctgtaac aggagtttta ggggtcatta gtgtagcatt
    11641 tagtatgcta agttcaaaat ctttaggaga aaaagataca gataagttca aaaaattagt
    11701 tagttctgta atgcatgcaa atgtaatcat aggttcgtta ttttttttca taattctatt
    11761 tttttcaaaa atctttatta gtgcaatata taaattttct gatgaactac tgagtgtggc
    11821 aactacatat ctatattcaa tgagcttcta tgttttatta acattaatca catttactct
    11881 tacgaatcta ttaaaagtcg aaaagaaaac gaattatata ttaacgatat ctataatatc
    11941 ttcactgatt caagtgcttt tgagttatat atttattaat ggcataggaa atttttcagg
    12001 tttaggtgtg tttggtgcag ggatagcatt aaatattaca ttactaataa caattttgtg
    12061 ctatctgata attgtaagag ctaccttttt ttcatgttta aagttaaagc caatatatat
    12121 aaaagatata ttgataagga gtattccttt agggattcaa gaattactag aaggaataat
    12181 atttttgatt ttttttgatg caatgattgc aagactagat acaatgtctt tgagtgtgta
    12241 ttctattatc agtcaagcat tagtatattt aaaattacca atgtttatgt atggtaatgc
    12301 agtgacaata tttgcaagtg aatactttgg agagaagaat aaaaataaaa tcatagtggt
    12361 aaaaagaata tctacatata tgtctatctt tttttatgta ttaataggaa taggtatata
    12421 cttaatgata gttccttttt ctaatttatt cacttttgat gataagctga taaacgaaac
    12481 aactaaaatg atactaccac tatttttttt agttagccca ataatactat atgaaataaa
    12541 taaatatata ttacaggtta tagaaaacgg aaaatttgtt gtgaaatgga ctcttataat
    12601 aaatataatt agtatgggaa ctatattgat gtttcatttt tacgggtctt tagatttgta
    12661 ttatatatat atggtgtatt ttggtaatta ccttatttta tctgcattat ttgaattgaa
    12721 gtttaaaaaa gtttgtatta gataatgatt tttagttatt aaactcctta gtcaacataa
    12781 tccgaatata aaaaagtgcc taccagttca ttgattggta ggcacttttt tgtgaaatgg
    12841 aattggttta tttttaaccc tatggaactc attcaatttt gaacttaaaa aaattgttaa
    12901 aaatatgaaa agttgttata tttgattctg ttacgaagtt tgatttaaac ttcttcaatt
    12961 tctcatgact ttagtcagga aaggttgaac agatgagctg ttactataaa gataacaaat
    13021 tgattttatt ggataatagc tgatacgccg aaatgatcac taattacagg cgtacttttt
    13081 ccatcgaaaa cgatttgata gctagaaacg gataactctt gtgaagcaaa aatataatca
    13141 atgcgcaatt tttcctgatt ctccccccag ccatcgatgg ctttttcaac ggtgtgttct
    13201 ccgacttttt gatctgctgc taaaaagctg tcttgcaact gcaatgagct agtgagaaca
    13261 aggtcgtagc cagttttagc gactgaagcg ggattgttga aatcgcccat aagcaatagt
    13321 ggtgaagagt ggttttgtaa tgcttgttcc gtttgcttcc actcgtaaga aaaaccacca
    13381 gtttctagcc accaagagta atgacaacag actgccgtta ttggttttcc cgctaattct
    13441 gtttggccga taagtaaaac tctagtgcgg tagtcatttg gattttgttc ttcggaaact
    13501 acaactgttt ttgggtggat cggctgtttt gaaagaaggg caacgccttc gtggtaggtg
    13561 gagtaaccaa tatgattgta agcccaactc caatgataat catgtccttg ttcttttaaa
    13621 agctgaacca aaaggtatgc aaaattatct tcgtggatcg gcagttgctt ttcagacggg
    13681 tgaaagttgt atggtgaaac aactggtaag ctatcaatgc gttgattaac ttcttgtaga
    13741 gcaatcaggg catactcttc ttgggtgatt tgggttgcca attggtgtaa tttttctaag
    13801 ggttcatttt ctaaccaact gtgagtgttc aatgttagta ccttcatatt tattcctcct
    13861 gcagtgataa aaaatagggg agtgataaaa ctctgcgagc tttacaccgc ccctatttag
    13921 gatttgttct gattaaatat ctaaacggcc aatagcagtt ccaggatctt gattaccaac
    13981 tttatctaaa tggaaggcat tgatcttttc gccatttgta aagacgacga tcatggttgt
    14041 ttgtttaccg gctgctttga ttttttctaa gtccgctgtg gcgatttttt cacctgctgt
    14101 tactttttgt ccttctgtta cgaggatcgt aaaggctgac tctttcattt cgattgtatc
    14161 taatcccatg tgaactaaga cttcaatacc ttcttctgtt tgaataccta atgcatgttt
    14221 agatgggaaa atactgctga tcacaccatc gattggggcg taaatcgttt cgtttgtagg
    14281 attaacggca aagccatcac ccatcatttt ttgcgaaaag acaggatcat tgacttgctc
    14341 gatagcgatt acttcaccat tggcaacagg cacgatcgtt tttgtgagac caagataatc
    14401 tgagttactt gctgttatag cgatcgtttc ggtttgctta ggcgtaggaa tggcagcgcc
    14461 agaatctagt aagtcttgaa tatctgattt taacacatcc gcttttggtc cgtaaacggc
    14521 ttgaacccca ttatctttta cgatcaatcc catagcacca gcttttttcc aagcatcctc
    14581 tgtgccgact ttgctcttat cagtgacgct aacacgtaag cgggtcatgc acgcatccac
    14641 atctacaata ttttcttttc cgcctagcag atgaatgata tcgatgattt gagggtcgat
    14701 tccatctgta ttttgagtgt tgcttgttgt tgcatttgtt tgtgtttcat tgttatcgta
    14761 gttgccattt ctacctggtg tcgcgaagtt gaattttttg atcatgaaat tggcgatgaa
    14821 atacgtcaaa acgccaaatg cgattgtaca aagtacgaaa ttcagtaaat caccacctaa
    14881 gccagctttt atggctaaag gtgttcgggt cagtagttcg atatttccaa atgaatgaac
    14941 acgtaatgaa acgatatccg ccatagcaaa tgccgcacct tggatgatgg catacacaac
    15001 atacaatggc actgctgcaa acataaacat aaattctaaa ggttctgtaa ccccggttag
    15061 gaatacagct aaagcggctg aaagatacat tgatttatag tttgaacgtt tatcaggatc
    15121 gacattacga tacatcgcaa gtgtcattcc catcaaaata ccagaagcgc cgatcatttg
    15181 tccaactttg aaacgagcag gcgtccagtt tgccaaaaca taattgtatt gagaggtatc
    15241 accagctcct tttaggttga ctaaatcagt tgcccaagct aaccataatg gatcttgacc
    15301 gaatacttgc gttccagctt gtgcgccaga taagatttcg taagttccgc ctaattgtgt
    15361 atagttgatc ggaatcgtca acatatgatg taaaccaaac ggtaacagta aacgttccaa
    15421 cgttccgtat aaaaatggtg ctagaatcgg tgcggtatct tgggattgag cgatccaaag
    15481 gccaaaatta ttgatacccg cttgaataga aggccaaata atagctaaaa gaattgcaac
    15541 gattgttgac caaagaatca cgacgaaggg aacaaaacgt ttgccgttga aaaacgaaag
    15601 agcatcgggt aatttacggt aattatagta tttattaaaa gccattgcgc cgacaaaacc
    15661 agcgatgatt ccaacaaaaa cccccatatt taatgcaggt gcttctaaca cactagtgaa
    15721 gaaaccttta accatgattt ttgtaccaaa taaggtgtgt gtaaaagctt tgtcatccgc
    15781 taacatgtca ctagtgacgc cgaagatcga accggttatt cggttgatta aaataaaaga
    15841 aagtccggca gcaaatgccc cgccagcacg ctctttcgcc caacttccac caattgcaag
    15901 tgcgaacaaa atatgcaagt tgccgatgac gccccaacca atattttcga taacgccacc
    15961 agttgtcgtt agtgctgccc aatctggatt gatcagagga atcgttttac cgatactgat
    16021 cattaatcca gcagctggca taacggctat cacgaccatt aaggctttac cgaacttttg
    16081 ccaaaactcg aaacttaata attttttcat cttttttctc tcctttgcaa taattgcgca
    16141 atcgttttcg ttgactgtag tataaagcag ttttttattt ttgtaaaccc ttaaataaaa
    16201 tcagctcttt tttattactg ataaaacgat agtatcatta tagataaaga attttcaact
    16261 aataagtagt gagcagcaaa gaaatgtttg acaatgcaat cggttgcgtt tattatgatg
    16321 ttaagaagca aaacatttac aggaggagag aaaatgaatc atttatttga aatagaccca
    16381 tggaaaattg ctacacatca attagaacgt aacgaacgtc gtcttcaaga gtcgctgacc
    16441 tcaatgggga acggatatat gggaatgaga gggaattttg aagaacacta tacaggagat
    16501 caccatcaag gaacctattt agctggtgtt tggtatccag acaaaacgag agtcggttgg
    16561 tggaaaaatg gctatcctga atactttgga aaagttatca atgccgtgaa ttttatcgcg
    16621 atggatattt ttgtgaatgg tgaagtactt gatttaggaa ttcaagaacc aaaagatttt
    16681 tatttagaat tagatatgca taacggattg ttgacacgca catttattct tgaaaaagaa
    16741 gaggcaagag ttaaattccg atttgaacgt tttttaagta ttgtgcaaca agaactagct
    16801 gtgattcgtg tgacagcaga agtgcttgaa ggaactgcgg atattcaaat tatttctaaa
    16861 atcgatggcg atgttcgcaa tgaagatagc aactatgatg aaatgttttg ggaagcacaa
    16921 caatctggtt ttgaagaagc aatcggcttt ttaacaacta agacgatacc gaatccgttt
    16981 ggcattgaac aatttagtgt aacagctgcg atgaaacatg tcacagaggc caaagcaggt
    17041 gtggctgaaa cggaaccttt gaaagtacaa caatcgtttc aagcgaatct acaagcaagt
    17101 gaatcaatca cgctagaaaa acaagtcatt gttttaacaa gccgtgatat tccagaagcg
    17161 gaacaacaag aaaaagcagt tcaactatta aatcaaacga ctaaaacgtt cgctgaacta
    17221 ttgaatgagc aaaacgccgc gtggagaaag cgctgggaac ttgccgatgt tgtaatcgaa
    17281 ggagacgatg cagcgcaaca aggtattcgt tttaatttat tccaattatt tacaacttat
    17341 tacggtgaag atgaacggtt gaacattgga ccaaaaggtt ttacaggtga aaaatatggc
    17401 ggtgccactt attgggatac agaagcttac gcggttcctt tgtatttagc gttggccaaa
    17461 ccagaagtga caaaaaatct attgaaatac cgctataacc aattagaaca agcaaaacac
    17521 aacgctcgcc aacaaggatt agcaggagcg ctctatccaa tggtgacatt tacaggaatt
    17581 gaatgccaca atgaatggga gatcaccttt gaagaaatcc accgcaatgg tgcgattgcg
    17641 tatgctatct acaattatgt gaactatact ggagataacg agtatttaaa aaatgaagga
    17701 ttacaagttc tcactgaaat cgcacgtttt tgggcggacc gcgttcattt ttctaaacgt
    17761 actggaaaat acatgatcca tggcgtgaca ggaccaaatg aatatgaaaa taatatcaac
    17821 aacaactggt atacaaacac gatcgccaca tgggtattgc aatatacctt agaaaattac
    17881 gacaagtatc aagcagaaac accagttaaa atttcaaaag aagagcaagt acattggcaa
    17941 gaaatcattg aaaatatgta ctatccattt gatgaagagt taggcgtttt tgttcagcat
    18001 gataccttct tagataaaga tttaatgccg agaacagcat taacctcagc ggatttacct
    18061 ttgaatcagc attggtcttg ggatcgtatt ttacgctctt gctttattaa acaagcggat
    18121 gtattacaag gtatttactt ctttggcgaa cgtttttcac gagcggaaaa agaacgtaat
    18181 ttcttatttt atgagccgat gacggttcat gaatcttctt tatcaccaag tgttcacgca
    18241 gttttagcgg cagaattagg gatggaagaa aaggcagtag aaatgtatca acggacagct
    18301 cgtttagact tagataatta caacaatgat accgaagatg ggttgcatat cacgtcaatg
    18361 acagggagtt ggcttgcaat cgtgcaagga tttgcgcaaa tgaagacggc tgacgagcaa
    18421 ttaagttttg ccccattctt accaagcacg tggacaagct atgcctttca tgtgaactat
    18481 cgtgatcgtt tgctttatgt gacggtggat caagacaatg ttcgattaca acttgtttca
    18541 ggagcagaac taccacttac tttatatgga aataagctgg ttttagcaga tgaattagta
    18601 atcgagatgg aaaaggtgaa tcctcatgtt taaaggtgtt ttatttgatt tagatggtgt
    18661 tttaacggat acagcagagt atcattatca agcgtggcaa cggttaggaa aagaaatcgg
    18721 catcacgatc gatcgtacgt ttaatgaaga gttgaaaggg gttagtcgtg aagactcatt
    18781 gaccttatta ctcgctcatg gcggcaaaac aaatgacttc acttcagcag aatttgctga
    18841 actagccaag cggaaaaatg agtattatgt agaaatgatc caacaagtta gcccaaaaga
    18901 tgtttatcca ggcattctgg atttgttaaa gaatttaaaa aaacaaggaa ttaaaatttc
    18961 tttagcttct gctagtaaaa acggtccctt tctgttagag aaaatggcgt tgatgcccta
    19021 ttttgatgga attgctgacc cgagcgccgt tgcaaaagga aaaccagacc cagagatttt
    19081 tcaattagca gctaaaaatg ttggactaca agcagcagaa tgtatcggaa tcgaagatgc
    19141 gaaagcgggg attcaagcca ttattgcaag ccatgcctta ccgatcgggg taggacgttc
    19201 agaagatctg ggggcaaata tcgcgcttgt ttcttccacg aaagaattaa cgtttgaatt
    19261 cttgttatct gtctggcaaa cagcaaaagc agatagttga tttcactgtt tatttaaacg
    19321 actatgcttg aaagaaaaag acgatagcaa caaagcatca atctatggta ttattttcta
    19381 cgatggaatg atttattaaa atttgtacga ttaatcatga aaggaggaga atagatgaca
    19441 attactgtta aagatgttgc taaaaaagct ggtgtggcta cttccactgt ttccagagtg
    19501 atcaacgacc actcaagtat ttcagatgct acgaagaaaa aagtctataa agtaatggaa
    19561 gaaatgggat atgtccccaa cattgcggct agaaatttag gcaaacgttc atcaggagca
    19621 gtcggtgtga ttttaccgcc gttagattct cgtgagcgga tgggaaatcc attttatttg
    19681 gaaatcattg agtcgatcaa tgatgaagcc cgtaaacaca gtatgacaac ggcaattgcc
    19741 acggcgcaat cttttgagac gttgttagaa aatgttcagc tgatgcatcg tcaaaagcaa
    19801 gtcgatggat tcatcttgct ttactcagat aaagaggatc cagtcatcga ttatttattc
    19861 gaaaatcaag ttcccttctc attgatcggt cagccgtata caaatgaaga taaggtcatt
    19921 tacgtggaca atgataatca attactgggc aaacatgcca ctgattacct aatcgaaaat
    19981 gggcatagaa atattctgtt tattacgaat accacccatg aaaatgttta ttatgaacgc
    20041 tattttggct atcaaaaggc gatgatgtta gcgaatttgc cagtattgcc ttcagtggat
    20101 atggaaaagc cagaagatta tgtagcattt gagcaacttt tgaaagagac gaaggctaca
    20161 gctgctgttg tcatcgatga tatcttcgcg atgcgaatga ttcaattagc acaaatgtat
    20221 ggctatcgtg tgccagatga tttttcggtg atcagtttta ataattcgat ttacgccact
    20281 ctcgttcatc cttatctcac cagtatcgat attgatattg cagagcttgg tcgaatgggc
    20341 atgcaaaaac tgattgagtc actgcaggaa aaagaagcga caggggttcg gatggtgatt
    20401 ccgcataagt tgattaagcg ggagacggta ctgtctttga aataataacg aatgaaatag
    20461 ttttgaacat tctacggaaa ggatgttcaa aactattttt ttagattagt tcataaaatg
    20521 actagatctt taggttgaca aatagaatat tctgctttaa tatgaaggag aaatgattcg
    20581 actacaaata tagtcgatgt ggatataaac ataaaaaatg atgcaaataa aaaaggagat
    20641 ggaaaagatg gaagcaaaaa catttgatat agaagggatg acctgtgctt catgtgcgca
    20701 aacggtagaa agggcaactg ccaaactaac aggtgtatcc aaagcaacag ttaacctagc
    20761 aactgaaaag ctaaacgttg aatatgatga aagcaaactt tcagaaagtg acatccaaaa
    20821 agctgtagca gatgcaggat acgaagcatt aagtaacgtc caacaacgaa catttgatat
    20881 agaaggaatg acgtgtgcct catgtgcgca aacaattgaa aaagcaacgg ctaaattgaa
    20941 cggtgttaca aaagcatccg tcaacttagc aacagaaaaa atggttgttg attttgatcc
    21001 gtcagcaata aacgtttctg atattaccaa agctgtatca gatgctgggt atgaagcaat
    21061 cgagcaagtg aattctacag acactgtaga caaagaccgt gagaaaaaac aaaaacatat
    21121 caaagacatg tggcaacgtt tttggatgtc tgcagtcttc actgttccat tattatatgt
    21181 agcaatgggg catatggttg gcttgccatt gccatcattt gtagatccaa tgatgcatcc
    21241 agaaacattt gctatggttc agttgatctt gacgatccct gtattatatt taggcagaag
    21301 tttcttcaca gtggggttta aagccttatt taaaggacat cccaatatgg attcactagt
    21361 tgctctagga acgagtgctg ctgtagcata cagtttgtac ggaacagcga tgatttttgc
    21421 tggcgatcca caattcacaa tg
//
