LOCUS       c00060_NZ_SMBU..       17346 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SMBU01000060.1 Pelomonas saccharophila strain DSM 654
            Ga0310527_1060, whole genome shotgun sequence.
ACCESSION   NZ_SMBU01000060
VERSION     NZ_SMBU01000060
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:32:49
            Original ID  :: NZ_SMBU01000060.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2211
            Orig. end    :: 19557
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17346
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[12211:14776]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12565
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..17346
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17346
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     CDS             304..1140
                     /locus_tag="ctg60_5"
                     /transl_table=11
                     /translation="MKKLDAHAATYRWLRRPLCRRYAVVVFNTFSKLKQRIDPNSNRTI
                     CWAFGTLLNGDSEILGAWHPDTNAATPPEVFGQLYHRGIEFVRCGLGDLVDVEAAFKAA
                     FRNSATYPSIEQTLTATLADVEPRHRSGMSRLLRAAVGDPVDEGSTVSSPDISSAELRE
                     RYPKLTLQWHEAVARFQPLFALPEPYCRLVRSVDQAAAEVQGRLEREIHRHGPFVDSDE
                     AFDFVVARLRRADLQLDREARAAQHARDASAWQSRRRLPPSGGTVGATTLAYRVLP"
     PFAM_domain     334..945
                     /aSDomain="Transposase_mut"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00872.20"
                     /description="Transposase, Mutator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_5_0001"
                     /evalue="3.80E-07"
                     /label="ctg60_5"
                     /locus_tag="ctg60_5"
                     /protein_end="214"
                     /protein_start="10"
                     /score="29.4"
                     /tool="antismash"
                     /translation="YRWLRRPLCRRYAVVVFNTFSKLKQRIDPNSNRTICWAFGTLLNG
                     DSEILGAWHPDTNAATPPEVFGQLYHRGIEFVRCGLGDLVDVEAAFKAAFRNSATYPSI
                     EQTLTATLADVEPRHRSGMSRLLRAAVGDPVDEGSTVSSPDISSAELRERYPKLTLQWH
                     EAVARFQPLFALPEPYCRLVRSVDQAAAEVQGRLEREIHRH"
     CDS             1137..1628
                     /gene_functions="regulatory (smcogs)
                     SMCOG1126:extracytoplasmic-function sigma-70 factor (Score:
                     78.6; E-value: 8.5e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg60_6"
                     /transl_table=11
                     /translation="MSTNWRKLFSDTKAALLRRGRTEDDADDLVQTAYLRVADQTQNNH
                     IENLDGYFMRTALNLSIDAHRTARARGEAALPDDQLLLVEDPGPGLDDVLLGRECIERM
                     DVCLGRLSERTRQMFMEYRVEGMTLEEIARKHELNISTVHHHLSKAMFQVAGGMNGWWP
                     "
     PFAM_domain     1179..1343
                     /aSDomain="Sigma70_r2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04542.16"
                     /description="Sigma-70 region 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_6_0002"
                     /evalue="1.00E-05"
                     /label="ctg60_6"
                     /locus_tag="ctg60_6"
                     /protein_end="69"
                     /protein_start="14"
                     /score="25.3"
                     /tool="antismash"
                     /translation="ALLRRGRTEDDADDLVQTAYLRVADQTQNNHIENLDGYFMRTALN
                     LSIDAHRTAR"
     aSDomain        1191..1592
                     /aSDomain="TIGR02937"
                     /aSTool="tigrfam"
                     /description="sigma70-ECF: RNA polymerase sigma factor,
                     sigma-70 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg60_6_0001"
                     /evalue="2.60E-17"
                     /identifier="TIGR02937"
                     /label="ctg60_6"
                     /locus_tag="ctg60_6"
                     /protein_end="152"
                     /protein_start="18"
                     /score="60.9"
                     /tool="antismash"
                     /translation="RGRTEDDADDLVQTAYLRVADQTQNNHIENLDGYFMRTALNLSID
                     AHRTARARGEAALPDDQLLLVEDPGPGLDDVLLGRECIERMDVCLGRLSERTRQMFMEY
                     RVEGMTLEEIARKHELNISTVHHHLSKAMF"
     PFAM_domain     1443..1589
                     /aSDomain="Sigma70_r4_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08281.14"
                     /description="Sigma-70, region 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_6_0003"
                     /evalue="5.40E-12"
                     /label="ctg60_6"
                     /locus_tag="ctg60_6"
                     /protein_end="151"
                     /protein_start="102"
                     /score="45.3"
                     /tool="antismash"
                     /translation="RMDVCLGRLSERTRQMFMEYRVEGMTLEEIARKHELNISTVHHHL
                     SKAM"
     CDS             1712..2695
                     /locus_tag="ctg60_7"
                     /transl_table=11
                     /translation="VWLVSLHGPDRNRAMEDEFRAWQAKSPAHREAFEKTTDVWQAVPN
                     TQAARDHMASIAQRPVREPVRARGTPWRWAAAAACLSALVVGGAVITQQWREQGVYATV
                     VGEQRSVLLDDGTRMLLNTDTRLRVDYGAKQRTVEVAGGEALFEVAKDAARPFVVRVAG
                     SEVVAVGTAFSVRFIDSPKHDDALTVTLIEGRVNVRPTVGGGDSLAPKEAVVLKPGDRL
                     TLDHNARARAPVVESKVDRPNIERAMAWKRNEIAFQDTPLAGAIDEINRYSRTQVELSP
                     EVQQANLDVSGVFRTGDSASFANAVALLHGLKVRENNGRLELEKFR"
     PFAM_domain     1715..1819
                     /aSDomain="DUF4880"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16220.7"
                     /description="Domain of unknown function (DUF4880)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_7_0004"
                     /evalue="6.30E-08"
                     /label="ctg60_7"
                     /locus_tag="ctg60_7"
                     /protein_end="36"
                     /protein_start="1"
                     /score="32.4"
                     /tool="antismash"
                     /translation="WLVSLHGPDRNRAMEDEFRAWQAKSPAHREAFEKT"
     PFAM_domain     2009..2299
                     /aSDomain="FecR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04773.15"
                     /description="FecR protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_7_0005"
                     /evalue="1.70E-16"
                     /label="ctg60_7"
                     /locus_tag="ctg60_7"
                     /protein_end="196"
                     /protein_start="99"
                     /score="60.7"
                     /tool="antismash"
                     /translation="VYATVVGEQRSVLLDDGTRMLLNTDTRLRVDYGAKQRTVEVAGGE
                     ALFEVAKDAARPFVVRVAGSEVVAVGTAFSVRFIDSPKHDDALTVTLIEGRV"
     CDS             2774..5779
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 83.9; E-value: 2.2e-25)"
                     /gene_kind="transport"
                     /locus_tag="ctg60_8"
                     /transl_table=11
                     /translation="MLKKLNAKHRRQARWLPIPITLSLLVGCGAACAAEPTLAARYQIE
                     QPAQGMEDALRAIARVTGTSVVFNSRNLAGRTARAVSGRLSGAEAIAEAIKGSGLELQV
                     TPDGAVVVRPIAAPAAAPAGSTPARDRNGAASRPDGIQASAEEDAPRSPNRAGDRADQV
                     QEFSRVEVTGSRLRRIEVDGPAPVNVYTAKDIERSGQPSLQRFLASLTEVSASTGEGGF
                     SRTPGQGTVQLRGLPLGSTLVLVNGRKLEAVGSSTGAVFNLNLIPLAAIERVEVVPSGS
                     SAVYGGDALAGVVNIILKKSIDGQSLSARLGSGRGLGDGALSLATGGHTADGSYLIMGS
                     FSRSTPLSMQDRNFFDSGDFRSIGGADERLSYCAPGTVTSLSGNLPGLSTNVAGIPNVN
                     GGQSLTIADFQATAGTRNLCNLYTTGGGGALIHGSQTFAIHSLAEHRLAGSWSAFGEVM
                     FVKDRIEAPGYGVLVGMTVPAANLFNPFGADVRVRSVLGNENGNQGVLRKGRFTRVLAG
                     VKGELASDWDAELTASTSSDHGDSVSRNDAVNYTTLATALASTDAATAFNPFTAGRAAS
                     GDVLRSILSDTIRRDRGRKDQVSAIARGNVGQLWAGPVDVVIGAEAARDWYDMSVPGQS
                     EIHGSRGSSAAYGELRAPLLAGHEDGRSDWSLAAVTLAARRDNYSDFGSAGTFQGGLEV
                     RPTRNLLVRAYAAGSFKPPTLLQTNVSEITYQAAIYGLVDPARNNEAITTGTVVRTTNK
                     ELMPEHGQARGIGAVWEPEGGLGTRLSATYWQLKIRSMIAVLSPQTALNYESAFPSFVT
                     RGPSVNGQPGAVTSVKSAEVNFGHLDTAGTDVDVAYAWKTSIGRVTAALGGTRVNEYRV
                     QLAPGAPVVDRLGRRFTDFWAPQWKGRMSAGIDDRTWSVGLTSRYLGAYKDAGTSERRL
                     GGYWMHDVAGSLNLKRLWPDAFPSFSGALFGLSVTNLTDRQPQYVPGVPYFDITQADWR
                     GRYVTARVTLDW"
     PFAM_domain     3317..3652
                     /aSDomain="Plug"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07715.17"
                     /description="TonB-dependent Receptor Plug Domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_8_0006"
                     /evalue="2.10E-19"
                     /label="ctg60_8"
                     /locus_tag="ctg60_8"
                     /protein_end="293"
                     /protein_start="181"
                     /score="70.2"
                     /tool="antismash"
                     /translation="DGPAPVNVYTAKDIERSGQPSLQRFLASLTEVSASTGEGGFSRTP
                     GQGTVQLRGLPLGSTLVLVNGRKLEAVGSSTGAVFNLNLIPLAAIERVEVVPSGSSAVY
                     GGDALAGV"
     PFAM_domain     4289..5767
                     /aSDomain="TonB_dep_Rec"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00593.26"
                     /description="TonB dependent receptor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_8_0007"
                     /evalue="8.50E-19"
                     /label="ctg60_8"
                     /locus_tag="ctg60_8"
                     /protein_end="998"
                     /protein_start="505"
                     /score="68.9"
                     /tool="antismash"
                     /translation="LRKGRFTRVLAGVKGELASDWDAELTASTSSDHGDSVSRNDAVNY
                     TTLATALASTDAATAFNPFTAGRAASGDVLRSILSDTIRRDRGRKDQVSAIARGNVGQL
                     WAGPVDVVIGAEAARDWYDMSVPGQSEIHGSRGSSAAYGELRAPLLAGHEDGRSDWSLA
                     AVTLAARRDNYSDFGSAGTFQGGLEVRPTRNLLVRAYAAGSFKPPTLLQTNVSEITYQA
                     AIYGLVDPARNNEAITTGTVVRTTNKELMPEHGQARGIGAVWEPEGGLGTRLSATYWQL
                     KIRSMIAVLSPQTALNYESAFPSFVTRGPSVNGQPGAVTSVKSAEVNFGHLDTAGTDVD
                     VAYAWKTSIGRVTAALGGTRVNEYRVQLAPGAPVVDRLGRRFTDFWAPQWKGRMSAGID
                     DRTWSVGLTSRYLGAYKDAGTSERRLGGYWMHDVAGSLNLKRLWPDAFPSFSGALFGLS
                     VTNLTDRQPQYVPGVPYFDITQADWRGRYVTARVT"
     CDS             5881..8205
                     /locus_tag="ctg60_9"
                     /transl_table=11
                     /translation="MRLVLLAPACALLWAVTSATAEQAPPGPSVRDVVEFTRIVQPMGS
                     DAEELRRQVSPDGTRAFIVVRRADVASDRNHYEIQLLSLRPEQLGSGHPPAPETVYSFD
                     SDQDPYNGDLALQQVRWLDDQALLFTGRIETGFNQAYRLDLSTKAVTRLTYETAPIVSF
                     DVSRDGRRIVYAVQVPNPPMQDGARSIVIGTQSFWSVKWGQQRLQSQVRKYRCYVADIG
                     AASKPRPLGEPFYEANVAKPVVSIAPDGRWALLPRYEPERTLAWSRDYPLLGEVMARWA
                     PALQADPLRYYTGTLLKTARRMTAWRLDDGQEQVVVDAPDDAMLGMPQYRSDRLWQGEG
                     DSVVLAGTHLPKAADGSLQKESYVIEYWPDSGRWKVIAKMEGRVANAHATPDGFVVIDG
                     DKPRRFKRSGAAGWREAADAEKQSAGPAWTPRIQQALNEPADVVADGPSGVTVRLTQLN
                     PHFNVATWGVMKPYAWRDLKGGEWSGGLLGPQDMDRRGRLPLVIQTYSIDPDAFYLDGP
                     NFGIGFSSAYPGRAFVREGVLVLAMGFWPRNGARGIDGYSKLTQFYGGVRAAVDALVKD
                     GLVDPARVGIIGFSTTGEITLNLVTFSDLPIRAATLADGDTNTLFNYAVAYGVEGWQQM
                     EEMNRGLPYGPARDQWLRNDPALNTDCVRAALRIEAYGAPVYGNYDIYSLLRRQYKPVE
                     MVLIPGGAHSLSMPSERMISLQGNVDWYRFWLKGEQRTEILLHGESAASLEAQYALWQQ
                     MEKMKAARDAEPRCPREPSRG"
     CDS             complement(8208..9989)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 292.5; E-value:
                     1.1e-88)"
                     /gene_kind="transport"
                     /locus_tag="ctg60_10"
                     /transl_table=11
                     /translation="MPNLGSLGSALHLIRTSADRTARLNAMGALLLVVLGGTLAAGSPL
                     ALKHLVDAMATPAPGGAGGTASPTLLLGAAYLVMLVAGRLASDVRPLLVSEVEQRVIAA
                     MRQRFFAHLQRLPMSYLVNRRSSELVHAVDLAIAGAQATISHLTNSIAPVLIELALMAI
                     ILAQLHQPGLVALFVATSALYLAAFAVGVMRQRPAIQAMSAASLDVYAQLGDGISHVET
                     LRCFGASDHAEKSLDVASSHLRSQWRWFNRLTLQSALAASVIFAATLAACFAIASNAVA
                     QGRLSVGGFVLASIYMLQMVRPLEVLGAAARDLSRAAGFMRPLLGILAQPTETLTGNSS
                     AADRKPPTTASTLRLENLHFGYDPQRPIIRGLDLDVLAGRTTAIVGRSGSGKSTLVRLL
                     LRLYEPQAGRILMDGLPIDSLQVAELRTRIGLVPQDTSLLQASVSSNIALGLPEARHDA
                     IECAARRAQIHGLIAALPHGYGTLLGDRGQTLSGGERQRLAIARAMLREPSLYVLDEPT
                     SMLDAKTEAAVLQSLRELTAGCTTLVIAHRLSTVMHADEIVVLDGGRVHERGSHAQLLA
                     QNGLYAQLWRQQTDSAA"
     PFAM_domain     complement(8436..8879)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_10_0009"
                     /evalue="1.50E-32"
                     /label="ctg60_10"
                     /locus_tag="ctg60_10"
                     /protein_end="518"
                     /protein_start="370"
                     /score="113.1"
                     /tool="antismash"
                     /translation="GLDLDVLAGRTTAIVGRSGSGKSTLVRLLLRLYEPQAGRILMDGL
                     PIDSLQVAELRTRIGLVPQDTSLLQASVSSNIALGLPEARHDAIECAARRAQIHGLIAA
                     LPHGYGTLLGDRGQTLSGGERQRLAIARAMLREPSLYVLDEPTS"
     PFAM_domain     complement(9078..9905)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_10_0008"
                     /evalue="3.60E-20"
                     /label="ctg60_10"
                     /locus_tag="ctg60_10"
                     /protein_end="304"
                     /protein_start="28"
                     /score="72.8"
                     /tool="antismash"
                     /translation="ALLLVVLGGTLAAGSPLALKHLVDAMATPAPGGAGGTASPTLLLG
                     AAYLVMLVAGRLASDVRPLLVSEVEQRVIAAMRQRFFAHLQRLPMSYLVNRRSSELVHA
                     VDLAIAGAQATISHLTNSIAPVLIELALMAIILAQLHQPGLVALFVATSALYLAAFAVG
                     VMRQRPAIQAMSAASLDVYAQLGDGISHVETLRCFGASDHAEKSLDVASSHLRSQWRWF
                     NRLTLQSALAASVIFAATLAACFAIASNAVAQGRLSVGGFVLASIYMLQMVRPL"
     CDS             complement(10001..11824)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 106; E-value: 3.3e-32)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_11"
                     /sec_met_domain="Asn_synthase (E-value: 8.2e-23, bitscore:
                     71.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFRYVAFSWLPAHQEASEVAARLEQALRVSRRWTLAFGMNGQRVY
                     MTGAASGINGAYRLPTSHGVILGRLFRRDAATPNPASDVAITEAEAQRIVRSDGRELIE
                     KFWGRYIAFLPSWTGEPRVLRDPTGTLPCYRIEIQGVSIVLSWLEDLSSLLDVPMPSVD
                     WEAAAAHMALGQVSGRRTLLEGVTQLLAGELTPMATGRGEPLQLWSAVDCARSPASSSP
                     TAATQRLRDTVEQCVGSWASCYESIVLRLSGGVDSAILLAHLAPRSHLRGLTCLNYYSP
                     GTDSDERSYARLAAQKQGATLLEQTVDDGYRLTDVLDVARTPIPANYLGSMGTSRTDAA
                     VAALHQAGSVFNGAGGDQLFFEMRCTWPAADYLKLRGFGRGFFGATLDAAHLGNASFWK
                     SLRQAVSDQSFRGNPVEGAGKFLTLTKREAIDAALQSAHRFVHPGWLAAEDLPIGKFHQ
                     LGMVISPLEYYNHYLREAAPERVHPLMSQPLMELCLATPTFVLTHGGRGRGLARSAFAD
                     LIPAEIARRRSKGGAEDYIATVLKRNLPFAREMLMDGVLMKHGLLDRAQVESALAGRPG
                     SKATYMTEIHACIATEAWLQRATTRAASAHA"
     PFAM_domain     complement(10037..11140)
                     /aSDomain="Asn_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00733.23"
                     /description="Asparagine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_11_0010"
                     /evalue="8.80E-20"
                     /label="ctg60_11"
                     /locus_tag="ctg60_11"
                     /protein_end="596"
                     /protein_start="228"
                     /score="71.8"
                     /tool="antismash"
                     /translation="LRDTVEQCVGSWASCYESIVLRLSGGVDSAILLAHLAPRSHLRGL
                     TCLNYYSPGTDSDERSYARLAAQKQGATLLEQTVDDGYRLTDVLDVARTPIPANYLGSM
                     GTSRTDAAVAALHQAGSVFNGAGGDQLFFEMRCTWPAADYLKLRGFGRGFFGATLDAAH
                     LGNASFWKSLRQAVSDQSFRGNPVEGAGKFLTLTKREAIDAALQSAHRFVHPGWLAAED
                     LPIGKFHQLGMVISPLEYYNHYLREAAPERVHPLMSQPLMELCLATPTFVLTHGGRGRG
                     LARSAFADLIPAEIARRRSKGGAEDYIATVLKRNLPFAREMLMDGVLMKHGLLDRAQVE
                     SALAGRPGSKATYMTEIHACIATEAWLQ"
     CDS             complement(11837..12565)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg60_12"
                     /sec_met_domain="PF13471 (E-value: 9.6e-22, bitscore: 67.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 3.5e-13,
                     bitscore: 39.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSVAAHSSPYRLADHVHACHFDGQVVLLDTRRNKYLGVGGAQLA
                     ALSRCIAGWPVTSQDQAPPAKHESLDALVKPLLDQQMLTAASTSRQPALVLDEPLESFD
                     SWHPTQDPSNWRDLLSMAYCASLTAVWLKKRCLAEIAISVRRLRLKEPSGQVETNPEHM
                     RAAVASYLRLRPFLFTAHDRCLHDSLTLVRFLATKRLFPRWVIGVRTRPFAAHSWVQSG
                     PIVLNDVYEHARDYTPILVI"
     PFAM_domain     complement(11846..12136)
                     /aSDomain="Transglut_core3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13471.8"
                     /description="Transglutaminase-like superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_12_0011"
                     /evalue="2.90E-17"
                     /label="ctg60_12"
                     /locus_tag="ctg60_12"
                     /protein_end="240"
                     /protein_start="143"
                     /score="62.8"
                     /tool="antismash"
                     /translation="VRRLRLKEPSGQVETNPEHMRAAVASYLRLRPFLFTAHDRCLHDS
                     LTLVRFLATKRLFPRWVIGVRTRPFAAHSWVQSGPIVLNDVYEHARDYTPIL"
     CDS             complement(12630..12752)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_13"
                     /transl_table=11
                     /translation="VDQDPELQLEIVELGDANQATKGSPQGVATELNEAVTYKP"
     CDS_motif       complement(12687..12752)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: VDQDPELQLEIVELGDANQATK"
                     /locus_tag="ctg60_13_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12630..12686)
                     /prepeptide="core"
                     /locus_tag="ctg60_13_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="8.80"
                     /molecular_weight="1843.0"
                     /monoisotopic_mass="1841.9"
                     /core_sequence="GSPQGVATELNEAVTYKP"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="VDQDPELQLEIVELGDANQATK"
                     /leader_location="[12686:12752](-)"
     CDS             complement(12829..12951)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_14"
                     /transl_table=11
                     /translation="MNDALELELVDLGDAKEQTKGYISGVPSELNEAAPYKQQP"
     CDS_motif       complement(12892..12951)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MNDALELELVDLGDAKEQTK"
                     /locus_tag="ctg60_14_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12829..12891)
                     /prepeptide="core"
                     /locus_tag="ctg60_14_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="14.00"
                     /molecular_weight="2130.3"
                     /monoisotopic_mass="2129.0"
                     /core_sequence="GYISGVPSELNEAAPYKQQP"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MNDALELELVDLGDAKEQTK"
                     /leader_location="[12891:12951](-)"
     CDS             13256..14287
                     /locus_tag="ctg60_15"
                     /transl_table=11
                     /translation="MENSVHNADRPTTWHIYWQAALGRDLLLRPELAERIRNRLLAAHD
                     VGGRKLLYYLLMPREIHLISILRPEDSTASFATGVSNVIGKWVREADGAFGPVFADRYQ
                     AQRVDTVEALRSEVRMLAWRPVAAGLQALPTNYANSALRAILGLCLPNGFHATALFDWL
                     GGSVPQERTALQRALAVEPSNLEIVRWELVKGLVSARGTVGPSGPMARRVRGASAGLVA
                     ASRDRSVDGALKLLERWVEVKLGLHGGHGLSSRKGMEGARGRALVANLAMRSGLCSAAC
                     VARHYGRAKATLSEQMTASSARAADQAILSIPMEQIVREAIALATHPAVGGGGGGGGGG
                     GGR"
     CDS             complement(14762..15772)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 169.7; E-value:
                     2.3e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg60_16"
                     /transl_table=11
                     /translation="MRYVVSVDKSAELLRQAIPLMSRQATALHPVSYAVWYEYVALSNP
                     GLRKAVDESLAKHGRLDEAKTYALHRKHIAEVDPATAEQIADGFERVLSGMSHSATAAG
                     TQAERYAEVLGSLKAGLAGAAEAPVNEVLRQTADMVQAVANLQAQLKESRKEILDLRSE
                     VHRARHESLVDALTGLANRRRFDQELATLLLDADALPNSADRPCLIMTDIDHFKRINDT
                     YGHAFGDKVLKAVAQALSSVVADAGIVARIGGEEFAILLPAAPVAQAEELAERVRFTIA
                     TSRIRRSSGEELESITVSLGVTAALPQQAPLDLLARADAALYMSKQGGRDRVTAV"
     aSDomain        complement(14771..15268)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg60_16_0002"
                     /evalue="7.10E-43"
                     /identifier="TIGR00254"
                     /label="ctg60_16"
                     /locus_tag="ctg60_16"
                     /protein_end="334"
                     /protein_start="168"
                     /score="144.2"
                     /tool="antismash"
                     /translation="HESLVDALTGLANRRRFDQELATLLLDADALPNSADRPCLIMTDI
                     DHFKRINDTYGHAFGDKVLKAVAQALSSVVADAGIVARIGGEEFAILLPAAPVAQAEEL
                     AERVRFTIATSRIRRSSGEELESITVSLGVTAALPQQAPLDLLARADAALYMSKQGGRD
                     RVT"
     PFAM_domain     complement(14777..15259)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg60_16_0012"
                     /evalue="1.40E-43"
                     /label="ctg60_16"
                     /locus_tag="ctg60_16"
                     /protein_end="332"
                     /protein_start="171"
                     /score="148.5"
                     /tool="antismash"
                     /translation="LVDALTGLANRRRFDQELATLLLDADALPNSADRPCLIMTDIDHF
                     KRINDTYGHAFGDKVLKAVAQALSSVVADAGIVARIGGEEFAILLPAAPVAQAEELAER
                     VRFTIATSRIRRSSGEELESITVSLGVTAALPQQAPLDLLARADAALYMSKQGGRDR"
     CDS             complement(16184..17170)
                     /locus_tag="ctg60_17"
                     /transl_table=11
                     /translation="MSLASEPVPPSAEDAAASVSLSPLLPADAIEGWDQIKRQMTSLLR
                     RTDPDAAWIGQFDQATQRMQALARRNPDAALYLLLQAAANEVDRYSAHHAMLCALVCEL
                     CAAWFEWPDDEVRTLVRAALTMNLSMSATQDALAQQLSPLSEAQRQEIEAHAANSSLLL
                     AAASVADPLWLDVVRQHHDAPHASGETAPPPAERLAQLLHRVDVYTAKLSRRASREPTS
                     PAIAARDACLDAAGLPDAIGATMLRVLGLYPPGCFVRLASEETGVVVRRGSKAHTPIVA
                     SLRRSDGGLYLQPVRRDTTSRQHAVVRGVGINEVKVRLHHERVLSVA"
     CDS             complement(17175..17345)
                     /locus_tag="ctg60_18"
                     /transl_table=11
                     /translation="GKTKKAYVWVYRTTNFVSQRAVYYDFCKDRSAWLELLDQGWNLTA
                     DSAVPQSQLAH"
ORIGIN
        1 ggccgacttc cagccttgcg ataaaggacc ggtggacttc cgcgcgatga gcaagctctt
       61 cctggctgat ttcaagacgc cctcggcgcg cctttatctc tgccgcagct gccttgacta
      121 cacgagcatc ctgcgtcgac cccattcgta ggaatgtcga gattgctgcg cacatatgca
      181 cccgcatatg tggtacaaaa tgacgttgcg actatcggtt aggtaaggcg caaaaaggcg
      241 cgtcagatca cccctgacga cgctgtcctg gcccgcttgc gatccaagtc gaggagcagt
      301 gcgatgaaga agcttgatgc ccacgcggcg acgtaccgtt ggctgcggcg cccgctatgt
      361 aggcgctacg ccgttgtggt tttcaacacc ttttccaagc tgaagcaaag gatcgacccg
      421 aattcaaacc gaacgatttg ctgggcgttc ggcactctgc tgaacggaga cagcgagata
      481 ttgggcgcgt ggcatcccga cacgaatgcc gcaacaccgc ccgaggtgtt cggtcagctc
      541 tatcaccgag gtatcgagtt cgtccgctgc ggcttgggag atctcgtgga cgtcgaggcg
      601 gcattcaagg ccgcgtttcg gaattcagcg acgtacccgt ccattgaaca gacgctcacc
      661 gcgacgttgg ctgatgtcga accgaggcat cgctccggaa tgtcgcgcct tctgcgagcc
      721 gctgtcggcg atccggtgga tgaaggctca acggtctcgt cgcccgacat ttcaagcgct
      781 gaattgcgtg aaagataccc aaagctaacg ctgcaatggc acgaagccgt tgcacgattt
      841 cagccgctct ttgctctgcc cgaaccctac tgtcgcctgg ttcgttcggt cgaccaggca
      901 gcagccgagg tgcaagggcg attggagagg gaaatccacc gacatggccc attcgtcgac
      961 tcagatgagg cgttcgactt tgtcgtcgcc aggctgcggc gtgccgatct gcagcttgat
     1021 cgagaggcga gggcggcgca gcatgcgcgc gatgcatccg catggcagtc ccgtcgccgc
     1081 ttgccgccat cgggtggcac cgtaggtgca acaacgctgg cctatcgggt attgccatga
     1141 gcacgaactg gcgcaagcta ttctccgaca cgaaggccgc gctgctgcgg cgtggccgga
     1201 ccgaggacga cgcggacgac cttgtgcaga cggcctatct ccgcgtggct gaccagaccc
     1261 agaacaacca tatcgagaac ctggacgggt atttcatgcg gacggcgctc aatctgtcca
     1321 tcgacgccca ccggaccgcg cgagcccgtg gcgaagcagc gctgccggac gatcagcttc
     1381 tcctcgtcga agatcctggc cccggtctgg atgacgtgct tctcggacgc gagtgcatcg
     1441 agaggatgga tgtttgcctg ggacgtctca gcgaacggac gcggcagatg ttcatggaat
     1501 acagagtgga aggcatgact ttggaagaga tcgcgcgaaa gcacgagctg aacatcagca
     1561 cggtccatca ccacctctcg aaggccatgt tccaggtcgc gggcggcatg aatggctggt
     1621 ggccatgagc cgttcagatc caggttctga tgagcgtacg aggcccgacg acaggcccag
     1681 ggtgacgcct gagatcgccg ctgaggcagc agtgtggctg gtgagcctcc acggcccgga
     1741 ccgcaaccgc gcgatggaag acgagtttcg tgcctggcag gcgaagtccc ctgcccaccg
     1801 cgaggccttc gagaagacga cggacgtctg gcaggccgtc ccgaacactc aggctgcgcg
     1861 agaccacatg gcgtccattg cgcagcgacc ggtacgcgaa cctgtgcgcg cgcgcggcac
     1921 gccctggcgc tgggctgccg cagcagcgtg cctgtctgct ctggttgtcg gcggcgcggt
     1981 gatcacgcag cagtggcggg agcagggcgt gtatgccacc gttgtcgggg agcagcgttc
     2041 ggtcctgctg gacgacggta cgcgcatgct gctgaacacg gacacacggc tgcgggtgga
     2101 ctacggcgcc aagcagcgca cggtcgaggt cgctggcggc gaagcgctgt tcgaggtggc
     2161 caaggatgca gcccggccgt tcgttgtacg cgtcgctggc agcgaggtcg tcgcagtggg
     2221 caccgcgttc tccgtgcgat tcatcgatag tcccaagcac gacgacgccc tcaccgtgac
     2281 gcttatcgaa ggccgggtga atgtacgacc gacggtcggg gggggggata gcttggctcc
     2341 caaggaagcc gttgtgctca aacctgggga ccgcctaacc ctggaccaca acgctcgggc
     2401 gcgtgcccct gtcgttgaat cgaaggtcga cagaccgaac atcgagcggg cgatggcctg
     2461 gaagcgcaac gagatcgcgt tccaggacac cccgcttgcc ggggccatcg acgagatcaa
     2521 ccgctacagc cgaacacaag tcgagttgtc gcccgaggtg caacaggcca acctggacgt
     2581 cagcggcgtt ttccgcactg gggacagcgc gtcgttcgcg aatgctgtcg cgctgttgca
     2641 cggcttgaag gtccgcgaaa acaacggacg gcttgaactc gaaaaattcc gatagagcta
     2701 gcacccccca tatccctctc gaagcccccg tcatcttgtt gtcaatccga cgacaacaaa
     2761 gcaagggtac gagatgctca aaaagctgaa cgccaaacat cgccgtcagg cgcgctggct
     2821 tcccattccc atcacgctct cactcctggt gggatgcggt gcggcctgtg ctgccgagcc
     2881 cacgctcgca gcgcgctacc agatcgaaca gccggcccag ggcatggagg acgcgcttcg
     2941 cgccatcgcg cgagtgacgg gcacatccgt tgtgttcaat tcaaggaacc tggccggccg
     3001 gaccgccagg gcggtgtcgg ggcgcctgtc gggcgcggag gccattgccg aggcgatcaa
     3061 ggggtcaggt cttgaactgc aagtgacgcc ggatggcgcc gtggtggtcc ggccgatcgc
     3121 ggcgcctgca gcggcgccgg ctggcagcac gcctgcacga gatcgcaatg gcgcggcgtc
     3181 tcgacccgac ggcattcaag catcggccga agaggacgcg cctcggtcgc ccaaccgcgc
     3241 cggagacagg gcagatcagg tccaagagtt ctcacgtgtg gaggtcaccg gatcgcggct
     3301 gcggcgcatc gaagtcgatg gaccagcgcc cgtcaatgtc tacaccgcca aggacatcga
     3361 aaggagcggg cagccgagcc tgcagcgctt cctggccagc ctgaccgagg tgtcggcgtc
     3421 gacgggggag ggcggtttca gccggacgcc cgggcagggc accgtgcagc tgcgcggcct
     3481 cccgctggga tcgacacttg tgctggtcaa cggtcgcaag ctggaggctg tcggatcatc
     3541 gaccggtgcc gtgttcaacc tgaacctgat ccccttggcg gctattgagc gcgtcgaggt
     3601 ggtgccttcc ggatcgtccg cggtctatgg cggtgatgcc cttgccggtg tggtcaacat
     3661 catcctgaag aaatccatcg acggccagtc gctatccgcg cggctgggct cgggccgagg
     3721 cctcggggac ggcgcgctgt cgctggccac gggcggtcac accgcggacg gcagctacct
     3781 gatcatgggc tcattcagcc gttccacgcc gttgtcgatg caggaccgaa acttcttcga
     3841 cagcggcgac ttccgcagca ttggcggcgc ggatgagcgc ttgtcctact gcgcgccagg
     3901 caccgtgacc agcttgagcg gcaaccttcc gggcctcagc accaacgtgg ccggcatccc
     3961 gaacgtgaat ggcggtcagt ccctgaccat tgcggatttc caggccaccg ctggcacgcg
     4021 aaacctctgc aacctgtaca cgaccggcgg cggtggtgcg ctgattcacg gcagccagac
     4081 gtttgccatc cactcgcttg ccgagcatcg cctcgcaggc agctggtcgg cgttcggcga
     4141 ggtcatgttt gtcaaggatc ggatcgaagc tcctggatac ggggtgttgg tcgggatgac
     4201 ggtgcctgcg gccaacctgt tcaatccctt cggcgccgat gtccgggtca ggtctgtcct
     4261 ggggaatgag aacggcaacc aaggtgtcct gcgcaagggg cgcttcaccc gcgtgctggc
     4321 cggggtcaag ggggaactcg ccagtgactg ggacgcggag ctgacggctt caacaagcag
     4381 cgaccatggc gactcggtct cgagaaacga cgcggtgaac tacacgacgc tggccaccgc
     4441 actcgcgtca accgacgccg ccaccgcgtt caacccgttc acggcgggac gggccgcgag
     4501 cggtgacgtg ttgcggagca tcttgtcgga cacgatccgc cgcgaccgcg ggcgcaagga
     4561 ccaggtcagc gccatcgcgc gcggcaatgt cggtcaactg tgggcggggc cggtcgacgt
     4621 tgtcatcggc gccgaggccg cgcgcgactg gtatgacatg tccgtccctg ggcagtccga
     4681 gatccacggc agccgtggca gctccgcggc ctacggcgag ctacgcgcgc cgcttctcgc
     4741 cgggcatgag gatgggcgca gcgattggag cctggctgcc gtcacgctgg cggcccgccg
     4801 cgacaactac agcgactttg gatcggctgg cacgtttcaa gggggactgg aggtccgccc
     4861 cacacgaaac ctgctggtcc gcgcgtatgc ggccggttcg ttcaagccgc cgacgctgct
     4921 gcagaccaac gtcagcgaga tcacctacca ggccgcgatc tatggcctgg tcgatcccgc
     4981 acgcaacaac gaggcgatca ccaccggcac cgtcgtgcgc acgacgaaca aggagctgat
     5041 gcccgagcat ggccaggcgc gtggcattgg cgcggtgtgg gagccggaag gcgggctggg
     5101 cacgcggttg agcgccacgt actggcagct gaagatccgg tccatgatcg ccgtcctgtc
     5161 gccgcagacc gcgctgaact atgagagcgc gtttccgtcg ttcgtgaccc gcggcccttc
     5221 ggtcaatggg cagcccggtg ccgtcaccag cgtcaagtcg gccgaggtca actttggtca
     5281 cctggacacc gcaggaacgg acgtggatgt ggcttacgcc tggaagacat ccatcggacg
     5341 cgtgacggcg gcgctgggcg gcacacgcgt gaacgagtac cgggtccagt tggcgccagg
     5401 tgcgccggtc gtcgaccgcc tgggtcgccg gttcacggat ttttgggcgc cgcagtggaa
     5461 gggccgcatg tccgcgggaa ttgacgaccg cacctggagc gtgggcctga caagccgata
     5521 cctgggtgcg tacaaggatg ccggcaccag cgagcggcgg ctgggcggct actggatgca
     5581 cgatgtcgcc ggcagcctga acctgaagcg actctggccg gacgctttcc ccagcttcag
     5641 cggcgcgctg ttcggcctca gcgtcaccaa cctcacggat cgccagccgc aatacgtgcc
     5701 cggcgtgccc tacttcgata tcacgcaggc cgactggcgc ggccgctacg tgaccgcgcg
     5761 cgtcacgctg gactggtagt ccctccgccg ggggctgcgg gtctgccgcc cctggctcct
     5821 tcctctcaat gcttcctgcc cacacgggcg ggagagccgc gcttttatcc ggaaaccatc
     5881 atgcgtcttg ttttgctcgc gcccgcgtgc gcacttctct gggcggtgac gtccgcaacg
     5941 gccgaacagg cgccccctgg cccgtcggtc cgcgacgtcg tggagttcac gcgcatcgtt
     6001 cagccgatgg gcagcgatgc cgaggaactc cgtcggcagg tgtcgccgga cggcacccgg
     6061 gccttcatcg tggttcgcag ggccgatgtg gccagcgaca ggaatcacta cgagatccag
     6121 ctgctgtcgc tgcggcccga gcagctgggc agcggtcatc cgccggcgcc cgaaacggtg
     6181 tactcgttcg attcggacca ggacccgtac aacggcgacc tggccctgca gcaggtccgt
     6241 tggctggacg accaggccct gctgttcacc gggcgcatcg aaaccggctt caaccaggcc
     6301 tatcggctgg acctgagtac caaggccgtc acccggctca cctacgagac cgcacccatc
     6361 gtctccttcg atgtctccag ggacgggaga cgcatcgtct atgcggtgca ggtgcccaac
     6421 ccgccgatgc aggacggtgc tcgcagcatc gtcatcggca cccagtcgtt ctggtcggtc
     6481 aagtgggggc agcagcgctt gcagtcccag gttcgcaagt accgctgcta tgtcgccgac
     6541 atcggagccg cctcgaagcc caggccgctg ggggagccgt tctatgaggc gaatgtcgcc
     6601 aagcccgtcg tgagcatcgc tccggacggc aggtgggcgc tcctgccccg ctatgagccg
     6661 gaacgaacgc tggcctggag tcgcgactac ccgctgctcg gcgaggtcat ggctcgctgg
     6721 gcgccggcat tgcaggcgga tccgttgcgc tactacacgg gaacgctgct caagaccgca
     6781 cgtcgcatga cggcgtggcg gctggacgat gggcaggaac aggtggtcgt ggatgcgccg
     6841 gacgacgcga tgctcgggat gcctcaatac cgttcggacc gactgtggca aggggagggg
     6901 gactcggtag tcctggccgg aactcatctg cccaaggcgg ccgacgggag cttgcagaaa
     6961 gagtcctatg tcatcgagta ctggccggac agcgggcgat ggaaggtcat cgccaagatg
     7021 gaagggcgtg tggcgaacgc gcatgcaacc ccggatggtt tcgtcgtgat cgatggcgac
     7081 aagccgcgtc gcttcaagcg ctccggcgcc gccggatggc gcgaggctgc ggatgccgag
     7141 aagcagagcg ccgggccggc atggacgccg cggatccagc aggccttgaa cgagcccgcc
     7201 gatgtcgtgg cggatggtcc ttcgggcgtg actgttcggc tgactcagct gaatccgcat
     7261 ttcaacgtgg ccacctgggg cgtgatgaag ccctatgcgt ggcgcgacct caaaggaggg
     7321 gagtggtccg gcgggctgct gggtccgcag gacatggatc gccgcggacg gctgccgctg
     7381 gtgattcaga cctacagcat cgatcctgac gcgttctatc tggacggtcc gaacttcggc
     7441 atcggcttca gcagcgcata ccccggccgt gccttcgtgc gagagggggt gctggtattg
     7501 gcgatggggt tctggccccg aaacggcgct cggggcatcg atggctattc caagttgacg
     7561 cagttctatg ggggtgtccg ggcggccgtg gatgcactgg tcaaggacgg gcttgtcgac
     7621 cctgctcgtg tcggcatcat cgggttcagc accacgggcg agatcacgct gaacctcgtg
     7681 acgttttccg atctgccgat tcgtgcggcg acgctcgccg atggcgacac gaatacgctg
     7741 ttcaactacg ccgtcgcgta tggcgtcgaa gggtggcagc agatggagga gatgaatcgt
     7801 ggcctgccgt acggccctgc gcgggaccag tggctgcgca acgaccccgc gctcaacacc
     7861 gactgcgtgc gcgccgcgct gcggattgag gcatacggtg caccggtcta tggcaactac
     7921 gacatctact cgctgctgcg gcggcagtac aagccggtgg agatggtgct gatcccgggc
     7981 ggcgcccatt cgctgtccat gccaagcgaa cggatgatct cgttgcaggg caatgtggac
     8041 tggtatcgct tctggctcaa gggggagcag cggaccgaaa tcctgctcca tggcgagagt
     8101 gccgcttcgc tggaggccca gtacgcgttg tggcagcaga tggagaagat gaaggccgcc
     8161 cgcgacgccg agccgcgatg cccgcgcgaa ccgagtcgcg ggtagcgtca ggctgcgctg
     8221 tcggtctgct gtcgccagag ctgcgcgtaa aggccgttct gcgcgaggag ctgggcgtgg
     8281 ctcccccgtt cgtgcacccg gccgccgtcg agtacgacga tctcatcggc gtgcatgacg
     8341 gttgagagtc tgtgggcgat gacgagggtc gtgcaccccg cggtcagttc gcgcaggctc
     8401 tgcagcaccg cggcctcggt ctttgcgtca agcatcgaag tgggctcgtc cagcacgtag
     8461 agcgagggct cgcgcaacat ggcgcgggca atcgccaggc gctggcgttc gccgccggac
     8521 agcgtctggc ctcgatcacc gagcagcgtg ccgtatccat gggggagtgc ggcgatgagc
     8581 ccgtggattt gcgcccgtct tgctgcgcac tcgatggcgt cgtggcgggc ttctggcagg
     8641 cccagcgcga tattgctgct gacgctagcc tgaaggaggc tggtgtcttg gggcaccagc
     8701 cctatcctcg tgcgcagctc tgcgacctgc agggaatcga tgggaagacc gtccatcagg
     8761 atgcggcccg cctgtggctc gtacaggcgc aacagcagcc gcaccagggt cgatttcccg
     8821 gagccacttc ggccgacgat ggcagtggtg cgacccgcga gcacgtcgag gtccaagccg
     8881 cgaatgatgg gacgctgcgg gtcatatccg aagtgcaggt tctccagacg gagcgtcgat
     8941 gcagtcgtcg ggggctttcg gtcagcggct gaagagttcc ccgtcaacgt ctcggtcggc
     9001 tgcgcaagga tgcccagcag gggacgcatg aagccggcgg cgcgcgacag gtctcttgcg
     9061 gccgccccca gcacctccag gggacgcacc atctgcagca tgtagatgct ggccagcacg
     9121 aaaccaccta cgctcagccg accttgggcc acagcgttcg aggcgatggc gaagcaagca
     9181 gccagcgtcg ccgcgaagat gaccgaggcc gcaagggcgc tttggagcgt cagtcggttg
     9241 aaccaccgcc actgagacct caggtgcgac gaagcgacgt ccagggactt ctcggcatgg
     9301 tccgacgcgc cgaaacaccg aagcgtctcg acatgcgaga tgccgtcacc gagttgggcg
     9361 tacacgtcga ggctcgccgc agacatggcc tggatggccg ggcgctgccg catcactccc
     9421 acggcaaatg ccgccaggta aagcgccgac gtggcgacga acaaggcgac gagcccaggc
     9481 tgatgcagtt gcgccaggat gatcgccatc aaggccagct cgatcagcac gggcgcgatg
     9541 ctgttggtga ggtgggaaat cgtcgcttga gcgccggcta tggccaggtc gacggcgtgg
     9601 accagttcgc tgctgcggcg attgacgagg tatgacatgg gcaggcgctg cagatgcgca
     9661 aagaatcgct gccgcatcgc ggcgatcaca cgctgctcga cctcgctcac cagcagcggc
     9721 ctgacatcgg aggcgagacg gccggcgacc aacatcacca gataggcagc gcccagaagc
     9781 agggtggggc tggcggtgcc gcccgctcca ccgggggcgg gagttgccat ggcgtcgacg
     9841 aggtgcttca aggccagcgg cgagcccgcc gcgagagtgc cgccgagcac gaccaggagc
     9901 agagcgccca tggcattgag tcgcgcggtt ctgtccgccg acgtccggat caggtgcagc
     9961 gcggatccaa ggctgccaag gttcggcatg gcgcggtgaa tcaggcgtgc gcgctggcgg
    10021 cgcgggtggt cgcacgctgc agccaagcct cggtggcaat gcaggcgtgg atctccgtca
    10081 tgtaggtggc cttcgagcca ggcctgccgg cgagcgctga ctcgacctga gccctgtcga
    10141 gcagcccgtg tttcatgagc acgccgtcca tcagcatctc gcgcgcgaaa ggcaggttgc
    10201 gcttcaggac cgtcgcgatg tagtcctcag cgcctccctt ggagcggcgg cgcgcgatct
    10261 cagcgggaat gaggtcggca aaggcgctcc tcgcgagtcc gcggcctctg cccccgtgcg
    10321 tcagaacgaa ggtcggtgtg gcgaggcaca gttccatgag cggttgtgac atcagcgggt
    10381 ggacgcgttc aggcgcagcc tcgcgcaggt agtggttgta gtactcgagt ggcgagatca
    10441 ccatgcccag ttggtggaac ttcccgatcg gcagatcctc ggcggccaac cagcctggat
    10501 gcacgaagcg gtgcgccgac tgcagcgctg catcgatcgc ttcgcgcttc gtcagcgtca
    10561 ggaatttccc ggcgccttcg acgggattcc cgcggaagga ctgatcgctc actgcctggc
    10621 gcagggactt ccagaaggac gcgttgccga ggtgggcggc gtccagggtt gccccgaaga
    10681 agccgcggcc aaagccacgc agcttcagat agtcggcggc gggccaggtg caccgcatct
    10741 cgaagaagag ctgatctccg ccggcgccgt tgaacacgga gcccgcttgg tgcaaagcgg
    10801 cgaccgcagc atccgtgcgg ctcgtgccca tggagccgag gtagttggcc gggatgggcg
    10861 ttcgagcgac gtcgagcaca tccgtcaagc gatagccgtc gtcgacggtt tgctctaaga
    10921 gcgtcgcacc ttgcttctgc gcggcgagcc gagcatagga gcgctcatca ctgtccgtgc
    10981 ccggggagta gtagttgagg caggtcagac ctcgcagatg tgatcggggc gccaggtggg
    11041 cgaggaggat ggcggagtcg acgccaccgg atagtcggag cacgatcgac tcgtagcagg
    11101 acgcccagct gccaacgcac tgttcgacgg tgtcgcgcaa ccgctgcgtg gcggcggtgg
    11161 ggctggacga ggcgggggat cgcgcgcagt caacggcgct ccagagctgt agcggctcgc
    11221 cacgacccgt tgccatcggt gtcagctcgc cagcaaggag ctgcgtcacg ccctccaaca
    11281 gcgttcggcg cccgctcacc tggccgagcg ccatgtgcgc ggccgcggct tcccagtcca
    11341 cggacggcat cggcacgtcc agcagcgaag aaaggtcctc cagccatgac aggacgatgc
    11401 tcacgccctg gatctctatg cggtagcagg gcagggtgcc cgtcggatct cgcagcacgc
    11461 gcggctctcc ggtccacgat ggaaggaacg cgatgtatcg cccccagaac ttctcgatga
    11521 gttctcgacc gtcggaacga acgatccgct gggcttctgc ttctgtgatg gcgacatcgc
    11581 tggctgggtt cggtgtagcg gcgtcgcgtc ggaacaggcg tccgaggatc acgccgtggc
    11641 tggtaggcag tcgataggcg ccattgatgc cggaggcggc tcctgtcatg tagacgcgct
    11701 gcccgttcat cccgaaggcc agggtccaac gccggctcac gcgcagcgcc tgttcgagcc
    11761 gggcggccac ttcactggcc tcttgatggg ctggcagcca gctgaatgcg acgtagcgaa
    11821 acatgcgcgg cgcctttcag atcacgagga ttggcgtgta gtcgcgcgcg tgctcgtaca
    11881 catcgttgag cacgatgggg ccgctctgga cccaggaatg cgcggcgaac ggccgggtcc
    11941 gcacgccgat gacccacctg ggaaacagac gcttggtggc aaggaatcgc accagcgtca
    12001 gcgagtcatg caggcaccgg tcgtgggccg taaaaaggaa ggggcgaagc cggaggtaag
    12061 aagccaccgc agcacgcatg tgttcggggt tcgtctccac ctgacctgag ggctccttga
    12121 ggcgcaggcg acggacggag atcgcaatct cggccaggca tcgcttcttc agccagacgg
    12181 cggtcaacga agcgcagtag gccatgctca gcagatcgcg ccagttcgac gggtcttgag
    12241 tgggatgcca gctgtcgaag ctttccagcg gttcgtccag gaccaaggca ggctgacggg
    12301 acgtgcttgc cgccgtgagc atctgttgat caagaagtgg tttgaccagg gcgtcgaggc
    12361 tttcgtgctt cgctggtggc gcttgatcct gcgaggtcac gggccagcct gcaatgcacc
    12421 gggagagggc tgccaactgt gcgcccccga cgcccagata cttgttgcgc cgcgtgtcca
    12481 gcagcacgac ctgtccatcg aaatggcaag catgcacatg gtcggccagt cggtatggcg
    12541 acgagtgggc ggcgacagat cgcatggtgg ccctcatcga ggatggagga aggcaagtgg
    12601 agcgcgtgcc gagccacctg cgtggacggt cagggtttgt aggtgacggc ttcgttgagc
    12661 tcggtggcca cgccctgtgg cgatcccttg gttgcctgat tggcgtcacc gagctcgacg
    12721 atctcgagtt gcagctccgg gtcttgatcc acgatggttc cttcgggcaa atgggtgtcg
    12781 gagaaggcgt gcagcctgtc gactgcacgc cttcatggcc gcgcctggtc agggctgctg
    12841 cttgtacggc gcggcttcgt tgagctcact cggcacgccc gagatgtagc ccttggtctg
    12901 ttccttggca tcgcccaggt cgaccagttc cagttccagt gcatcgttca tgacgatctc
    12961 cttcggttga gttgagaaca cggatgcctt cggttttcac cttgggcgag ccaaaggtag
    13021 gcatctcgat tcgctgctca aagcaatttc tttggcgtcc gcctcgcgtt cggtcagctt
    13081 gaacgcgcgg atttggcgtc gttgttggcg ctggcgtcgt cgcgggctcg aaaaactttt
    13141 tttcgagcct ggaaggatcc gttcggtgta ttggttagcg ttttcttggg ccgaacgaag
    13201 tggctgcggt tcaaaactag gggggaaatt tgcttgccgg cgacgtcatg gtgttatgga
    13261 gaactccgtc cacaacgccg acaggccgac gacctggcac atttactggc aggcagccct
    13321 gggccgcgac ttgctgctcc gtcctgagct cgccgagcgg atccgcaacc gcttgttggc
    13381 cgcccacgat gtaggcggtc gaaagcttct ctactacctg ctcatgccca gagagattca
    13441 cctgatctcg atcctgcggc cggaggactc gacggcgagt tttgcgaccg gcgtgtcgaa
    13501 cgtgatcgga aagtgggtga gggaggccga cggcgctttc gggcctgtgt tcgctgatcg
    13561 ataccaggcg caacgcgtcg acaccgtcga ggccttgcgc agtgaagttc gaatgctggc
    13621 ttggcggccg gtcgcggccg ggcttcaagc cttgcccacg aactatgcga actccgccct
    13681 cagggcaatc ttggggctgt gcttgccgaa cgggttccac gccacggcgc tgttcgattg
    13741 gctgggaggt tctgtgccgc aggaacgcac tgcgctgcag cgagcgctgg ccgtggagcc
    13801 ttcgaacctc gagatagtcc ggtgggagtt ggtcaaaggc ctggtgtcag cgaggggcac
    13861 ggtcggcccc tcggggccga tggcacgacg ggtgcgaggc gcctctgctg gccttgttgc
    13921 ggccagcaga gatcggagcg tcgatggtgc gctcaagttg ttggagcgct gggtcgaggt
    13981 caagctggga ctgcatggcg gacacggcct gtcgtcgcga aaggggatgg aaggggcacg
    14041 gggcagggcg ttggtcgcca atctggccat gaggtcggga ctgtgctcag ccgcgtgcgt
    14101 cgcccgtcac tatgggcggg ccaaagcaac gctcagcgag cagatgacgg cgagcagcgc
    14161 gcgagcggct gatcaggcga tcctctcgat cccgatggag cagatcgttc gtgaagccat
    14221 tgctcttgcg acccatcctg ctgtcggagg cggaggcgga ggcggaggcg gaggcggagg
    14281 ccggtaagcc gggatgcgta cgcaattcat gatcaaggtg cagggagaaa accacatgtc
    14341 gaagactgtc aggaagcgcg tcgatgcaag ctcgctgctt gtgatcttgc ccaacgagaa
    14401 cctgtggaat aaagacaacc cgagaacgag tcgcaagttc atgcggaacg ccagcggccg
    14461 cttcaatgag catcccgggt ggcataacga cttgctcaga tgctcccgaa catgccttgc
    14521 agtccgagtt ggcccagcat tgcgcgccac cccagccgcc atcgccgcta ggattcgtca
    14581 tcgcctgtgg cttccccggc tgggcctgca cgccgaacac aactgtggcc ttcgaagctg
    14641 tggtggatgg ggcgcaaaca atgggtgaga tttctgaaga ggcgcttcag gccacgatgc
    14701 gatccgtcgg tcgcgatcag ttcaatggcg aagtccccgc gctgaccgac gaccgcatgc
    14761 ctcagactgc ggtcacgcgg tcgcggccac cctgcttgga catataaagg gccgcgtccg
    14821 cacgcgccaa tagatcgagc ggggcttgct gtggcagagc agcagtgacg cccagggaga
    14881 cggtgatgct ttcaagttct tcaccgctgg aacggcggat gcgactcgtt gcgatggtga
    14941 atctaacgcg ctccgccagc tcttccgcct gcgccaccgg cgcggccggg agcaagatcg
    15001 cgaactcttc gccgccaatg cgggcgacga tgccggcgtc agcaacgacc gacgaaagtg
    15061 cctgcgccac ggccttcaag accttgtcgc caaacgcgtg cccgtaggtg tcgttaatgc
    15121 gcttgaagtg atcgatgtcc gtcatgatca gacatggtcg atccgcagag ttgggcagcg
    15181 cgtcggcgtc caggagcaaa gtcgcgagct cttgatcgaa cctgcgccga ttggccaggc
    15241 ccgtaagagc gtccacaagt gactcgtggc gggcccgatg aacttcggag cgcagatcca
    15301 ggatttcctt gcgactttcc ttcaactgcg cctggagatt ggcgaccgcc tggaccatgt
    15361 cggcggtctg tcgcaggact tcgttgacgg gcgcttcggc ggcacctgca aggccggcct
    15421 tcagactgcc aaggacctct gcataacgct cggcctgcgt ccccgccgcc gtcgcagagt
    15481 gcgacatgcc gctgaggacg cgctcaaacc cgtcggcaat ctgttcggcg gtggcggggt
    15541 cgacctccgc aatgtgtttg cgatgcagcg cgtaggtctt ggcctcgtca agcctgccat
    15601 gcttggccaa ggactcatcg acggccttac gcagaccggg gttggagagg gcgacgtatt
    15661 cataccagac ggcatagctg acgggatgca gcgccgtcgc ctgccgggac atcaggggaa
    15721 tagcctgccg gagcagctcc gcactcttat cgaccgagac aacgtatcgc atgttcttcg
    15781 aggtgccgcc ttcagcgcgc cgcctccccg acacaactgg cgcggcagat gtggaagaaa
    15841 aagaaagcct cggcccagcg gccgaggctt caaagcctaa cgttcatatt tcgccgaggc
    15901 tcctgctcag ggaggaaaag caggggcaac gccttgcagc gcaaccgttt gcgactttac
    15961 caaagtcatt ttctaagggc tgtcggccgg cgtgcagccg gccagtcgcc gttcctgacg
    16021 gggcttccac aacgcccatc gggcgcatga tcggaagatg ccggggagcc gtgcgttcac
    16081 ggtcggattc catgaaggcg atgcgaaggc ccgtactgaa gtcgtgccat gtcgccaccg
    16141 acaacgccgt cgcatccctg cagcgatcgg aaacgacggt cgatcaggcg acgctcagca
    16201 cgcgctcatg gtggaggcga accttgacct cgttgatgcc aaccccgcgt accacggcgt
    16261 gttgccggct ggtcgtgtcg cgccggacgg gctgcaagta caggcctcca tcgcttcgcc
    16321 gcagcgaggc gacgatcggc gtgtgggcct tgctgccgcg acggacgacg acgccggtct
    16381 cttcactggc gaggcgcaca aagcaaccgg gcgggtacag ccccagcacc cgcagcatcg
    16441 tcgccccgat cgcgtcgggc agccctgccg cgtccaggca ggcgtctcgc gcggcaatgg
    16501 ccggggacgt cggttcgcgg ctggctctac ggctgagctt ggcggtatac acgtccaccc
    16561 ggtgcagcaa ctgggccagc ctttcggccg ggggcggtgc ggtctcgccg ctggcatggg
    16621 gggcgtcgtg gtgctgccgc acgacatcga gccacagcgg atcggcgacg ctggcggcgg
    16681 ccaagagcag cgaactgttg gccgcgtgcg cctcgatctc ctgacgctgc gcttccgata
    16741 gcgggctcag ttgctgagcc agggcgtcct gcgtcgccga catcgacagg ttcatcgtga
    16801 gcgcggcccg taccagcgtc ctgacctcgt cgtcgggcca ctcgaaccat gccgcgcaca
    16861 actcacagac cagcgcgcac aacatcgcgt ggtgcgcgct atagcggtcg acctcgttgg
    16921 cagcggcttg cagcaaaaga tacagcgccg cgtccggatt gcgtcgcgcc agggcctgca
    16981 tgcgctgcgt cgcctggtcg aactgcccta tccaagcggc atcagggtcc gtgcggcgca
    17041 gcagcgaggt catctgccgc ttgatctggt cccacccttc gatggcgtcg gcgggcaaga
    17101 gcgggctcag cgagacggac gctgcggcgt cctcagcgga agggggcaca ggttcggatg
    17161 cgagcgacat ccgatcagtg tgccagttga gactgaggga cggccgagtc tgcggtcaag
    17221 ttccatcctt gatccagcaa ctccagccag gccgagcggt ctttgcagaa gtcgtagtac
    17281 accgcgcgtt gcgacacgaa gttggtcgtg cggtagaccc acacataggc cttcttcgtc
    17341 ttgccc
//
