LOCUS       c00001_NZ_SMBU..       10828 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_SMBU01000001.1 Pelomonas saccharophila strain DSM 654
            Ga0310527_1001, whole genome shotgun sequence.
ACCESSION   NZ_SMBU01000001
VERSION     NZ_SMBU01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 16:32:49
            Original ID  :: NZ_SMBU01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 281235
            Orig. end    :: 292063
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10828
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[286235:287063](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5828
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10828
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10828
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             177..992
                     /locus_tag="ctg1_249"
                     /transl_table=11
                     /translation="MWVAERHRLILDLLQTHQRLTTEHFAEALGVSRETVRRDLIELER
                     SGHLARVHGGAVPPAAAPAVPPEPAYLERTGLQQPQKREIARLAATLIQPGQACFLDAG
                     STTLALAQELAQREGLIVITNSLDAAMVLACHRRHEVHLLGGRLEDDVPATYGEQTVAE
                     IARLQVDWALVSPVGIDAANGAMDYLWHEATVARAMLGRARQRVVLADASKLGQASRVQ
                     ICPPAEVDVLVTDGGADAAQLERLTAAGVKRVLQPEAVQRPTDSCAAAA"
     PFAM_domain     192..347
                     /aSDomain="HTH_DeoR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08220.14"
                     /description="DeoR-like helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_249_0022"
                     /evalue="6.20E-17"
                     /label="ctg1_249"
                     /locus_tag="ctg1_249"
                     /protein_end="57"
                     /protein_start="5"
                     /score="61.2"
                     /tool="antismash"
                     /translation="RHRLILDLLQTHQRLTTEHFAEALGVSRETVRRDLIELERSGHLA
                     RVHGGAV"
     PFAM_domain     411..881
                     /aSDomain="DeoRC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00455.24"
                     /description="DeoR C terminal sensor domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_249_0023"
                     /evalue="3.60E-45"
                     /label="ctg1_249"
                     /locus_tag="ctg1_249"
                     /protein_end="235"
                     /protein_start="78"
                     /score="153.9"
                     /tool="antismash"
                     /translation="QPQKREIARLAATLIQPGQACFLDAGSTTLALAQELAQREGLIVI
                     TNSLDAAMVLACHRRHEVHLLGGRLEDDVPATYGEQTVAEIARLQVDWALVSPVGIDAA
                     NGAMDYLWHEATVARAMLGRARQRVVLADASKLGQASRVQICPPAEVDVLVTD"
     CDS             complement(956..2236)
                     /locus_tag="ctg1_250"
                     /transl_table=11
                     /translation="MKRRDLLGLASLPLLAACTTPPAAPGAITPPAEAASAPAPAASAA
                     LPAPPPREWRAAWVATVANIDWPSKKGLPAEAQQAEIRGLCDVAARTGLNALILQVRSS
                     ADALYESTLEPWSEVLSGTQGRHPGYDPLTVWLAEAHARGLELHAWFNPYRARHSTAKS
                     APADNHLSRTHTGWVKRYGDQLWIDPGEPAAAEHTLAVVRELLTRYAVDGVHIDDYFYP
                     YPVQDAAKNDVDFPDEPSWQAYAAGGGSLARADWRRYNVNSLVQRLYALVHEVRPGARL
                     GISPFGLPRPDARPPGISGFSQFDKLYADVELWLREGWLDYLAPQLYWPRAQTAQAFET
                     LLQAWRALNPLGRPIHPGLFTSRIDSTPQSWLPEEILGQIDSIRRLSPGSGHIHFSMAA
                     LAQNRRGIADALRAGPYAAAAQESVGR"
     PFAM_domain     complement(1202..2077)
                     /aSDomain="GHL10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02638.17"
                     /description="Glycosyl hydrolase-like 10"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_250_0024"
                     /evalue="1.50E-57"
                     /label="ctg1_250"
                     /locus_tag="ctg1_250"
                     /protein_end="345"
                     /protein_start="53"
                     /score="195.1"
                     /tool="antismash"
                     /translation="WRAAWVATVANIDWPSKKGLPAEAQQAEIRGLCDVAARTGLNALI
                     LQVRSSADALYESTLEPWSEVLSGTQGRHPGYDPLTVWLAEAHARGLELHAWFNPYRAR
                     HSTAKSAPADNHLSRTHTGWVKRYGDQLWIDPGEPAAAEHTLAVVRELLTRYAVDGVHI
                     DDYFYPYPVQDAAKNDVDFPDEPSWQAYAAGGGSLARADWRRYNVNSLVQRLYALVHEV
                     RPGARLGISPFGLPRPDARPPGISGFSQFDKLYADVELWLREGWLDYLAPQLYWPRAQT
                     AQAFETLLQAW"
     CDS             complement(2233..3516)
                     /gene_functions="transport (smcogs) SMCOG1131:major
                     facilitator transporter (Score: 191.6; E-value: 2.6e-58)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_251"
                     /transl_table=11
                     /translation="MTRSPWAWVPSLYFAQGIPYVVVMTLSVVLYKNLGISNTDIALYT
                     SWLYLPWVLKPLWSPLAELFGTKRRWITALQFIIGAALAGVALTVPTDKVFQMSLAVLW
                     LMAFTSASHDIAADGYYMLALPQHRQAALVGVRSTFYRLANIAGQGGLVYLAGELSERT
                     GSVVDAWSLVFWLLGALFIGLAAWHSFVLPHPAADTPGAGRRAARGLLAEFFAVFAGFF
                     AKPGIAVILGFLLLYRFPEAQLLKLASPFLLDTVDKGGLGLSTKAVGFAYGTVGIGALT
                     LGGLVGGWVISRVGLKRALWPLVLAMHVPNLAFLALALTHPASLAVISAALAVEQFGYG
                     LGFTAYLMYMIHVAEGPQKTAHYALCTGFMALGMMIPGMWSGWLQDHIGYVPFFGWVLL
                     ATVPSFVMAALIRVPDDFGMKKPEGDRP"
     PFAM_domain     complement(3124..3468)
                     /aSDomain="BT1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03092.18"
                     /description="BT1 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_251_0025"
                     /evalue="7.20E-10"
                     /label="ctg1_251"
                     /locus_tag="ctg1_251"
                     /protein_end="131"
                     /protein_start="16"
                     /score="37.8"
                     /tool="antismash"
                     /translation="GIPYVVVMTLSVVLYKNLGISNTDIALYTSWLYLPWVLKPLWSPL
                     AELFGTKRRWITALQFIIGAALAGVALTVPTDKVFQMSLAVLWLMAFTSASHDIAADGY
                     YMLALPQHRQA"
     CDS             complement(3513..4394)
                     /locus_tag="ctg1_252"
                     /transl_table=11
                     /translation="MLNTETPSTRHPDLDSYATPALLDAFIADQNAAVAAVQAAAPQLA
                     AAVDAALPRIRAGGRLLYAGAGTSGRLGVLDSVELYPTFSWPRERAVAVIAGGASAMFV
                     AVEGAEDDRAQGAADLAALQPGPNDVALLLAASGATPYVLGAIEAARAAGALTIGFANN
                     PGAPVAAQADIGITLDTGPEVISGSTRLKAGTSQKIALNTFSSALMVRLNKVYGNLMVD
                     LKATNAKLVRRALALTVRASGASEADAQAALAQCDQHVKTALVMLGRGVGADEARALLD
                     AADGSVSRALHP"
     PFAM_domain     complement(3789..4016)
                     /aSDomain="SIS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01380.24"
                     /description="SIS domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_252_0026"
                     /evalue="1.40E-07"
                     /label="ctg1_252"
                     /locus_tag="ctg1_252"
                     /protein_end="202"
                     /protein_start="126"
                     /score="31.5"
                     /tool="antismash"
                     /translation="PNDVALLLAASGATPYVLGAIEAARAAGALTIGFANNPGAPVAAQ
                     ADIGITLDTGPEVISGSTRLKAGTSQKIALN"
     CDS             4614..4871
                     /locus_tag="ctg1_253"
                     /transl_table=11
                     /translation="MNASLKTGLGIAAAAAALFATTAFPTAAVAADGMVKCSGVNSCKG
                     TSECKTAKNDCKGHNSCKGQGWVSKASAAECTKAGGTVEK"
     CDS             5001..5828
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_254"
                     /sec_met_domain="DUF692 (E-value: 1.4e-98, bitscore: 323.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIQGFGLGLRVEHYAAFEAGVDAAVRPDWLEIISENYMVPGGP
                     PLAHLERIRADYPLVMHGVSLSVAGPAPLDLGYLRELKALADRLQPGWVSDHLCWSADA
                     HSQLHDLLPVPLTRAALDHVGARIAQVQDILGRPLVLENVSSYVRFKADEMPEWEFIAQ
                     LLQQTGAKMLLDVNNIYVSGRNHGFDPRAYLDGIPVEPVRQIHLAGHEDRGDIVIDTHD
                     HPVRDEVWQLYQYALMRFGAVPTMIERDDHIPSLPELLDELGVARRLAAEALR"
     PFAM_domain     5016..5810
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_254_0027"
                     /evalue="4.00E-107"
                     /label="ctg1_254"
                     /locus_tag="ctg1_254"
                     /protein_end="270"
                     /protein_start="5"
                     /score="357.4"
                     /tool="antismash"
                     /translation="GFGLGLRVEHYAAFEAGVDAAVRPDWLEIISENYMVPGGPPLAHL
                     ERIRADYPLVMHGVSLSVAGPAPLDLGYLRELKALADRLQPGWVSDHLCWSADAHSQLH
                     DLLPVPLTRAALDHVGARIAQVQDILGRPLVLENVSSYVRFKADEMPEWEFIAQLLQQT
                     GAKMLLDVNNIYVSGRNHGFDPRAYLDGIPVEPVRQIHLAGHEDRGDIVIDTHDHPVRD
                     EVWQLYQYALMRFGAVPTMIERDDHIPSLPELLDELGVARRLA"
     CDS             5825..6637
                     /locus_tag="ctg1_255"
                     /transl_table=11
                     /translation="MSVGAQQRQLAAAIRDGDDAPGLLAGDYATGLEVYRHAYRARLAA
                     ALADNYTVLARALGDEGFDALARAYIAAHPSQHPSIRWFGHELAGFMAAAGEGLVPHPG
                     LVDIARMDWALRNAFDAAAAAPLEPAALAALSPDDWAGLVLRLQPGVQRIALAHAIEPA
                     WRVLREWEPPTSEPGGVDQPELPEPVAHAHELLAWRQGLETRWRSLEPLEAALLDAVAA
                     GQPFALLCERAAAELGDAEAAAPAVIGALQQWLADGLLAASNSTVAQA"
     PFAM_domain     5840..6100
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_255_0028"
                     /evalue="1.20E-24"
                     /label="ctg1_255"
                     /locus_tag="ctg1_255"
                     /protein_end="92"
                     /protein_start="5"
                     /score="86.5"
                     /tool="antismash"
                     /translation="QQRQLAAAIRDGDDAPGLLAGDYATGLEVYRHAYRARLAAALADN
                     YTVLARALGDEGFDALARAYIAAHPSQHPSIRWFGHELAGFM"
     CDS             complement(6688..7308)
                     /locus_tag="ctg1_256"
                     /transl_table=11
                     /translation="MGVGVLQACSTCRTTSLVNVRPAAASQDFELQSSQPYVTRLLVPD
                     LLDARLGLCEPVSERFICLQLRIAPGRQAVLSQPTFRLSRSGLPREVLRFPEQQYQVLC
                     ESRGAASLKCPLPIEIASQPDAPKQLLHAGSHQDWRFERWAYTVEPMLTFQGLPGDPDP
                     PAWQLFSKYSTWRNYRLQLVPASRLDEGDTRLELPDIEIGGKR"
     CDS             7595..8131
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196:alkyl hydroperoxide reductase/ Thiol specific
                     (Score: 114.7; E-value: 4.7e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_257"
                     /transl_table=11
                     /translation="MPRTLKLTLAALSVALFLPVAHAALNVGATAPDFSADSAVGGQPF
                     KFHLADALKNGPVVLYFYPKAFTSGCTVEAHQFAEASDRFKALGATVIGMSNDDIDTLK
                     KFSVEACRNKFAVAADAGAKVMKDYDAALRLLPGMADRVSYLIGTDGRIAAVHASMSPE
                     GHIDAMLKAVQQLKK"
     PFAM_domain     7673..8059
                     /aSDomain="AhpC-TSA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00578.23"
                     /description="AhpC/TSA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_257_0029"
                     /evalue="5.30E-23"
                     /label="ctg1_257"
                     /locus_tag="ctg1_257"
                     /protein_end="155"
                     /protein_start="26"
                     /score="81.4"
                     /tool="antismash"
                     /translation="VGATAPDFSADSAVGGQPFKFHLADALKNGPVVLYFYPKAFTSGC
                     TVEAHQFAEASDRFKALGATVIGMSNDDIDTLKKFSVEACRNKFAVAADAGAKVMKDYD
                     AALRLLPGMADRVSYLIGTDGRIAA"
     CDS             8128..9501
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105:amidase (Score: 355.2; E-value: 9.7e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_258"
                     /transl_table=11
                     /translation="VIAGLGAAELLSAYCCGELSPVDAVQAVLAQAGRREGGLHALCAV
                     EAEAALAAARASEARWRAGSALALDGVPVTLKENIAVPGAAYRLGTAATPDGAVADFEA
                     PPAARLREAGAIRWARTTMPDYGMLSSGLSSLYAEPARNPWDVALTPGGSSAGAAAAAA
                     AGYGPLHLGTDIGGSIRLPAGWCGLVGLKPSHGRVPIKPGYAGRVAGPLTRTVADAALM
                     LAVLAQPDARDPTQLAPGAVSPRPLELRGLRLGLQLDAGWGEAVQPEVAAAIVAAARAF
                     EQAGAIVEPLAAFTTRETADGIDRFWRMRSWLDISALPPERRAKVLPYILDWVAPAAGY
                     DGATVFRGYSQMQALREAANAACEPFDFVLSPVSPMPAYPAHLASPLHDPARPFEHIAF
                     TLPSNMSEQPALAINAGYTGEGLPIGLQIVGRRFDDAGVLALGAAWEQLRPAQRSWPF"
     PFAM_domain     8197..9444
                     /aSDomain="Amidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01425.23"
                     /description="Amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_258_0030"
                     /evalue="1.40E-76"
                     /label="ctg1_258"
                     /locus_tag="ctg1_258"
                     /protein_end="439"
                     /protein_start="23"
                     /score="258.5"
                     /tool="antismash"
                     /translation="AVQAVLAQAGRREGGLHALCAVEAEAALAAARASEARWRAGSALA
                     LDGVPVTLKENIAVPGAAYRLGTAATPDGAVADFEAPPAARLREAGAIRWARTTMPDYG
                     MLSSGLSSLYAEPARNPWDVALTPGGSSAGAAAAAAAGYGPLHLGTDIGGSIRLPAGWC
                     GLVGLKPSHGRVPIKPGYAGRVAGPLTRTVADAALMLAVLAQPDARDPTQLAPGAVSPR
                     PLELRGLRLGLQLDAGWGEAVQPEVAAAIVAAARAFEQAGAIVEPLAAFTTRETADGID
                     RFWRMRSWLDISALPPERRAKVLPYILDWVAPAAGYDGATVFRGYSQMQALREAANAAC
                     EPFDFVLSPVSPMPAYPAHLASPLHDPARPFEHIAFTLPSNMSEQPALAINAGYTGEGL
                     PIGLQIVGRRFDDAGVL"
     CDS             complement(9511..9984)
                     /locus_tag="ctg1_259"
                     /transl_table=11
                     /translation="MRPIPAPPLHRRIRPSFGRVSVGVHGRVMVSMAEGPFDAGLMAAV
                     KRAIALAGRRLPADRRFGDLLEIRGSMEMDADALAELRASIHSFSNRGIVAVSTVFLVR
                     PGTPGIERLPALMDIWRASRPVRRADDFDSAWALVNADLAAAGLPLQAPPSRP"
     CDS             10116..10517
                     /locus_tag="ctg1_260"
                     /transl_table=11
                     /translation="MTHPIDAWHELAKARNPRALAALLAEDVVFHSPVVHTPQRGRALA
                     TQYLAAALAVLGNESFRYVREIRGERDALLEFELELAGVQVNGVDIIRWNDAGRITDFK
                     VMVRPLKGMQAVQQKMAELLAQMQQQQQQ"
     PFAM_domain     10131..10421
                     /aSDomain="SnoaL_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12680.9"
                     /description="SnoaL-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_260_0031"
                     /evalue="1.50E-11"
                     /label="ctg1_260"
                     /locus_tag="ctg1_260"
                     /protein_end="102"
                     /protein_start="5"
                     /score="44.9"
                     /tool="antismash"
                     /translation="DAWHELAKARNPRALAALLAEDVVFHSPVVHTPQRGRALATQYLA
                     AALAVLGNESFRYVREIRGERDALLEFELELAGVQVNGVDIIRWNDAGRITD"
ORIGIN
        1 cccgtgccag ccgtgtgacg ggccgcaatg tcacaaaaat ccacgacagt tctgcgacag
       61 atcggtgtct ttggcctgat ttccacgaat ttccacaagc gtcctcgcat tcacacaacc
      121 gccatctggc tgtggcccac tcaggccgcg ctccttcttc ccgtcccttg ccgcacatgt
      181 gggttgccga acgacaccgc ctcatcctgg acctgctcca gacgcatcaa cgcctgacga
      241 ccgaacactt tgccgaggcc ctgggcgtgt cccgggagac ggtgaggcgt gacctgatcg
      301 agctggagcg ctcgggccat ctggcccgcg tgcacggcgg cgccgtgccg cccgccgccg
      361 cgccggcggt gccgcccgag ccggcctatc tggagcgaac cggcctgcag cagccgcaga
      421 agcgcgagat cgcgcggctg gcggcgacgc tgatccagcc cggccaggcc tgcttcctgg
      481 atgccggctc cacgacgctg gcgctggccc aggaactggc ccagcgtgag ggcctgatcg
      541 tcatcaccaa ctcgctggat gccgccatgg tgctggcctg ccaccgccgc cacgaggtgc
      601 atctgctggg cggccggctg gaggacgatg tgcccgccac ctacggcgag cagaccgtgg
      661 ccgagatcgc gcggctgcag gtggactggg ccctggtgtc gccggtgggc atcgatgccg
      721 ccaatggcgc gatggactac ctgtggcacg aggccacggt ggcgcgcgcg atgctgggcc
      781 gcgcgcgcca gcgcgtggtg ctggctgacg ccagcaagct gggccaggcc agccgcgtcc
      841 agatctgccc gccggccgag gtggacgtgc tggtgaccga tggcggcgcc gacgccgcgc
      901 agctggagcg cctcacggcc gcgggcgtga agcgcgtgct gcagcccgag gcggttcagc
      961 gcccgacaga ctcctgcgcc gccgccgcat agggcccggc gcgcagggcg tcggcgatgc
     1021 cgcggcggtt ctgggccagt gccgccatgc tgaagtggat gtggccgctg cccggcgata
     1081 ggcgccggat gctgtcgatc tggcccagga tctcctcggg cagccagctt tgcggcgttg
     1141 aatcgatgcg gctcgtgaac aggcccgggt ggatgggccg gcccagcggg ttcagcgcgc
     1201 gccaggcctg cagcagcgtc tcgaaggcct gggccgtttg cgcgcgtggc cagtagagct
     1261 ggggcgcgag atagtccagc cagccctcgc gcagccacag ctcgacgtcg gcatagagct
     1321 tgtcgaactg gctgaagccg ctgatgcccg gcgggcgcgc atcgggccgc ggcaggccga
     1381 aggggctgat gccaagccgc gcgccggggc gtacctcgtg cacgagggcg tagagccgct
     1441 gcaccaggct gttgacgttg tagcgccgcc agtcggcccg cgcgaggctg ccgccgccgg
     1501 ccgcataggc ctgccagctc ggctcgtcgg gaaagtcgac gtcgttcttc gcggcgtcct
     1561 gcaccgggta gggatagaag tagtcgtcga tgtgcacgcc gtccaccgca tagcgcgtca
     1621 gcagctcgcg cacgacggcc agcgtgtgct cggcggcggc gggctcgccg gggtcgatcc
     1681 agagctggtc gccataacgc ttcacccagc cggtgtgagt gcggctgaga tggttgtcgg
     1741 ctggcgcgga cttggccgtg ctgtgccgcg cgcggtaggg gttgaaccag gcatgcagct
     1801 ccaggccgcg cgcatgggcc tcggcgagcc agacggtcag cgggtcgtag ccggggtggc
     1861 ggccctgggt gccgctcagc acctcgctcc agggttcgag cgtggattcg tagagcgcgt
     1921 cggcgctgct gcgcacctgc aggatcagcg cgttcagccc ggtgcgggcg gccacgtcgc
     1981 agaggccgcg gatctcggcc tgctgggcct cggccgggag acccttcttg ctgggccagt
     2041 cgatgttggc gacggtggcg acccacgcgg cgcgccattc gcgcggcggc ggtgccggca
     2101 aggcagcgga ggccgcgggc gcgggggcgg atgcagcctc cgcgggtggc gtgatcgcgc
     2161 cgggtgcggc gggcggcgtc gtgcaggccg cgagcagcgg caggctggcg aggccgagca
     2221 ggtcgcggcg cttcatggcc tgtctccctc gggcttcttc atgccgaaat cgtcgggaac
     2281 cctgatcagc gccgccatca cgaagctcgg caccgtcgcc agcagcaccc agccgaagaa
     2341 gggcacatag ccgatgtggt cctgcagcca gccgctccac atgccgggga tcatcatgcc
     2401 cagggccatg aagcccgtgc agagcgcgta gtgggcggtc ttctgcgggc cttcggcgac
     2461 atggatcatg tacatcagat aggccgtgaa gccgaggccg tagccgaact gctcgacggc
     2521 cagcgcggcg ctgatgacgg ccaggctggc cgggtgggtc aacgccagcg cgaggaaggc
     2581 caggttgggc acgtgcatgg ccagcaccag cggccacagc gcgcgcttca ggcccacgcg
     2641 ggagatgacc cagccgccca ccagcccgcc cagcgtcaac gcgccgatgc cgacggtgcc
     2701 gtaggcgaag cccacggcct tggtgctcag gcccaggccg cccttgtcca ccgtgtccag
     2761 caggaagggg ctggccagct tcagcaactg cgcctcgggg aagcggtaga gcagcaggaa
     2821 gccgaggatg acggcgatgc cgggcttggc gaagaagccg gcgaacacgg cgaagaactc
     2881 ggccagcagc ccgcgcgcgg cgcggcggcc ggcgccgggc gtgtcggccg cgggatgcgg
     2941 cagcacgaag ctgtgccacg cggccagccc gatgaacagc gcgcccagca gccagaacac
     3001 caggctccag gcgtccacca cgctgccggt gcgctcgctc agctcgcccg ccagatagac
     3061 cagcccgcct tggcccgcga tattggccag gcggtagaag gtcgagcgca cgccgacgag
     3121 ggcggcctgg cggtgctgcg gcagcgccag catgtagtag ccgtcggccg cgatgtcgtg
     3181 cgaggccgac gtgaacgcca tcagccacag tacggccagc gacatctgga agaccttgtc
     3241 cgtcgggacc gtcagcgcca cgcccgcgag cgccgcgccg atgatgaact gcagcgcggt
     3301 gatccagcgc cgcttggtgc cgaacagctc cgccagcggc gaccacagcg gcttgagcac
     3361 ccagggcaga tagagccagc tcgtgtagag ggcgatgtcg gtgttggaga tgccgaggtt
     3421 cttgtagagc accaccgaca gcgtcatgac gacgacatag gggatgccct gggcgaagta
     3481 caggctgggc acccaggccc atggcgagcg tgtcatgggt gcaatgcgcg gctcacgctg
     3541 ccgtccgccg cgtccagcaa tgcgcgtgcc tcatcagcgc ccacgccgcg cccgagcatc
     3601 accagcgccg tcttcacatg ctggtcgcac tgcgccagcg ccgcctgcgc gtccgcctcg
     3661 ctggcgccgg aggcgcgcac cgtcagcgcc agcgcgcgcc gcacgagctt ggcgttggtg
     3721 gccttcaggt ccaccatcag attgccgtag accttgttga gcctcaccat cagcgccgac
     3781 gagaaggtgt tcagcgcgat cttctgcgag gtgccggcct tgagccgcgt gctgcctgag
     3841 atgacttcgg ggccggtgtc cagcgtgatg ccgatgtcgg cctgggccgc gaccggcgcg
     3901 ccggggttgt tggcaaagcc gatggtcagc gcgccggccg ctcgcgcggc ctcaatggcg
     3961 cccagcacat agggcgtggc accggacgcg gccagcagca gggccacgtc gttggggccg
     4021 ggctgcagcg cggcgaggtc ggcggcgccc tgggcacggt cgtcctcggc gccctcgacg
     4081 gcgacgaaca tcgcgctggc gccgccggcg atcaccgcca ccgcccgttc gcgcggccag
     4141 gagaaggtgg ggtagagctc cacgctgtcc agcacgccca ggcggcccga ggtgccggcg
     4201 ccggcataca gcagccggcc gccggcgcgg atgcgcggca gggcggcgtc cacggccgcg
     4261 gccagctgcg gggcggcggc ctgcacggcg gcgacggcgg cgttctggtc ggctatgaat
     4321 gcatccagca gggccggggt ggcgtagctg tccaggtcgg gatgccgggt gctcggggtt
     4381 tcggtgttca gcatggggat ggcggcttca ggccgccgga ctctagcgcg gcaccgggcc
     4441 atgacgaatg ccacgggcca ttgcagtcat aacggcaggt aatcagaatc tgccggctgg
     4501 ctgtaaggac tcgccgagtc acacgacaca agctggcaag tcgatgcggg ctctactcgg
     4561 atcgacctgt ggtgatcccg atctcaacca cttctctttt ctggagactc caaatgaacg
     4621 catccctcaa gaccggcctg ggcatcgccg ccgccgctgc cgccctgttc gccaccaccg
     4681 ccttcccgac ggccgccgtc gcggccgacg gcatggtcaa gtgctccggc gtcaacagct
     4741 gcaagggcac ctccgagtgc aagaccgcca agaacgactg caagggccac aacagctgca
     4801 agggccaggg ctgggtcagc aaggcctcgg ccgccgagtg cacgaaggcg ggcgggaccg
     4861 tcgagaagta agaccacccc ctgccggctt cgccggcccc ctcaaggggg cactgcctat
     4921 ggcccggcaa agccggttcc atggcagtcg cttgatggcg cgcgtgcctg cggccgcgcg
     4981 tcgttttcgt ttgcactgac atgaccaaga tccaaggctt tggcctcggc ctgcgtgtcg
     5041 agcactacgc cgccttcgag gccggcgtcg atgccgccgt gcggcccgac tggctggaga
     5101 tcatttccga gaactacatg gtgcccggcg ggccgccgct ggcgcatctg gagcgcatcc
     5161 gggcggacta cccgctggtc atgcacggcg tgtcgctgtc cgtcgccggg ccggcgccgc
     5221 tggacctggg ctatctgcgc gagctcaagg ccctcgccga tcggctgcag cccggctggg
     5281 tgtccgacca cctctgctgg agcgccgacg cgcacagcca gctgcacgac ctgctgcccg
     5341 tgccgctgac ccgcgctgcc ctcgaccatg tcggcgcccg catcgcccag gtacaggaca
     5401 tcctcggccg tccgctggtg ctggaaaacg tgtccagcta tgtgcgattc aaggccgacg
     5461 agatgccgga gtgggaattc atcgcgcaac tgctgcaaca gaccggcgcg aagatgcttc
     5521 tggacgtcaa caacatttac gtttccggcc gcaaccacgg cttcgacccg cgcgcctatc
     5581 tcgacggcat ccccgtcgag ccggtgcgcc agatccacct cgccggccac gaggaccgcg
     5641 gcgacatcgt catcgatacc cacgaccatc cggtgcgcga cgaggtctgg cagctctacc
     5701 agtacgcgct gatgcgcttc ggcgccgtgc cgacgatgat cgaacgcgac gaccacatcc
     5761 cgtcgctgcc cgaactgctg gacgagctgg gtgtcgcgcg tcgcctggcc gcggaggccc
     5821 tgcgatgagc gtcggcgccc aacagcgtca gctcgccgcc gccatccgcg atggcgacga
     5881 tgcgcccggc ctgctggccg gcgactatgc gaccggcctc gaggtctacc gccacgccta
     5941 ccgcgcccgc ctggccgcgg cgctggccga caactacacg gtgctggccc gcgcgttggg
     6001 cgacgagggc ttcgatgcgc tggcccgggc ctatatcgcc gcgcatccca gccagcatcc
     6061 gtccatccgc tggttcggcc atgaactggc cggcttcatg gccgcggccg gcgagggcct
     6121 ggtgcctcat cccggcctcg tcgatatcgc ccgcatggac tgggcgctgc gcaacgcctt
     6181 cgacgccgcc gcggcggcgc cgctcgaacc ggccgcgctc gcggcgctga gccccgacga
     6241 ctgggccggc ctggtgctga ggctgcagcc cggcgtgcag cgcattgcgc tggcccacgc
     6301 catcgagccc gcctggcggg tgctgcgcga atgggagccc ccgacgtccg aacccggcgg
     6361 cgtcgaccag cccgagctgc ccgagcccgt ggcgcatgcg catgagctgc tggcctggcg
     6421 ccagggcctg gagacgcgct ggcgctcgct ggaaccgctg gaggccgctc tgctcgatgc
     6481 cgtcgccgcg ggccagccct tcgcgttgct gtgcgagcgt gccgccgccg agctgggtga
     6541 cgccgaggct gctgcgccgg ctgttatcgg agcgctgcag cagtggcttg ccgacggact
     6601 gctcgcggcg tcaaattcga cggttgctca ggcgtagacg gggcagactt gcatgggagc
     6661 gaccttcaca ttgaagggcg ggaatgctta gcgcttgccg ccgatctcga tgtcaggaag
     6721 ttcaagccgc gtgtcgccct catcaaggcg agaggcaggc accaactgca gtcgatagtt
     6781 ccgccaggtg gagtatttgg agaaaagctg ccacgccggt gggtccggat cgcccggtag
     6841 cccttggaac gtgagcattg gctccaccgt gtaggcccac cgttcgaagc gccaatcctg
     6901 gtgacttcca gcatgcagca gctgctttgg cgcatcgggc tgagatgcga tctcgatcgg
     6961 cagcgggcat ttgagcgacg ccgcgccgcg tgactcgcag agaacctggt actgctgttc
     7021 cgggaatcgc aagacctctc tcggaagacc gctgcgactg aggcggaagg tgggctgcga
     7081 cagcacggct tgccggccgg gcgcgatgcg cagctgcagg cagatgaatc tctccgaaac
     7141 aggctcgcac aaacccaggc gtgcgtcgag gagatcggga accagcaggc gggtcacgta
     7201 gggctggctg ctctgcagtt cgaaatcttg gcttgccgca gccggcctca cgttgaccag
     7261 gctggtcgtg cggcaggtcg agcaggcctg caggacgcca acgcccatca gcgcggccag
     7321 ttgaagcgtt cgacacgtcg tggaggcgtg atgaagtgaa ccggccctgt gtctcggtac
     7381 ccgctttgcc gccgtggacg cctggcccgg atctgcgggg ggcgcgggat ttctcatcag
     7441 attcccttga gatgggtgcc atgcagattt tgcgcgcctg cccgggctgc tgcgggttgc
     7501 caggcctgta gtgaccctgt gcgtggaacc cttcaggcgg cgcggtcgtg ccggcttggc
     7561 tatcctgccg cccacgtcat ttccgaggtg tgccatgccc cgtaccctga agctcacgct
     7621 tgccgcgctg tccgtcgcct tgttcctgcc cgtcgcccat gcggcgctca atgtgggcgc
     7681 cacggccccg gatttcagcg ccgactccgc cgtcggcggc cagcccttca aattccacct
     7741 cgccgacgcg ctgaagaacg gcccggtggt gctgtacttc tatcccaagg ccttcaccag
     7801 cggctgcacc gtcgaggccc accagttcgc cgaggcgagc gacaggttca aggccctggg
     7861 cgccaccgtc atcggcatgt ccaacgacga catcgacacg ctgaagaagt tcagcgtcga
     7921 ggcctgccgc aacaagttcg ccgtcgcggc cgacgcgggc gccaaggtca tgaaggacta
     7981 cgacgccgcc ctcaggctgc tgccgggcat ggccgaccgc gtgtcctacc tgatcggcac
     8041 cgacggcagg atcgccgccg tgcatgccag catgagcccc gagggccaca tcgacgcgat
     8101 gctgaaggcc gttcagcagt tgaagaagtg atcgccggcc tcggtgcggc cgagctgctg
     8161 tcggcctact gctgcggcga gctgtcgccg gtcgatgccg tgcaggccgt gctggcgcag
     8221 gccgggcgcc gcgagggcgg gctgcatgcg ctgtgcgccg tcgaggccga agcggcgctg
     8281 gccgcggcgc gtgccagcga ggcgcgctgg cgggccggca gcgcgctggc gctggacggc
     8341 gtcccggtca cgctgaagga gaacatcgcc gtgcccggcg cggcctacag gttgggcacc
     8401 gcggccacgc ccgatggcgc cgtggccgac ttcgaggccc cgcccgccgc acggctgcgc
     8461 gaagccggcg cgatccgctg ggcgcgcacg acgatgcccg actacggcat gctgagctcg
     8521 ggcctgtcca gcctctacgc cgagccggcg cgcaacccct gggacgtggc gctgacgccg
     8581 ggcggctcca gcgccggcgc ggccgccgcg gccgcggccg gctacggccc gctgcacctg
     8641 ggcaccgaca tcggcggctc catccgcctg ccggccggct ggtgcggcct cgtcggcctc
     8701 aagcccagcc atggccgcgt gcccatcaag cccggctatg ccggccgcgt cgccgggccg
     8761 ctgacccgca cggtcgccga cgccgcgctg atgctggccg tgctggccca gccggatgcg
     8821 cgcgacccga cccagctggc gccgggcgcc gtctcgcccc ggccgctcga actgcgcggg
     8881 ctgaggctgg gcctgcagct ggacgccggc tggggcgagg ccgtgcagcc cgaggtggcg
     8941 gccgccatcg tggccgccgc gcgcgccttc gagcaggccg gcgccatcgt cgagccgctg
     9001 gccgccttca cgactcgaga aacagccgac ggcatcgacc gcttctggcg catgcgctcc
     9061 tggctggaca tctcggccct gccgcccgag cgccgcgcca aggtgctgcc ctacatcctc
     9121 gactgggtgg cgcccgcggc gggctacgac ggtgccacgg tctttcgcgg ctacagccag
     9181 atgcaggcgc tgcgcgaagc ggccaacgcg gcctgcgagc ccttcgactt cgtgctgtcg
     9241 cccgtcagcc cgatgccggc ctacccggcc catctggcca gcccgctgca cgacccggcc
     9301 cggcccttcg agcacatcgc gtttacgctg cccagcaata tgagcgagca gccggcgctg
     9361 gccatcaatg cgggctacac gggcgagggg ctgcccatcg gcctgcagat cgtcggccgg
     9421 cgcttcgacg atgccggtgt gctggcgctg ggggccgcgt gggagcagct gcggcctgcg
     9481 cagcgctcct ggcctttctg acggccggct tcaggggcgc gaaggcggcg cctgcagcgg
     9541 caggccggcg gcggcgagat cggcgttgac cagggcccag gccgagtcga agtcgtcggc
     9601 gcggcgcacc gggcggctgg cgcgccagat gtccatcagc gcgggcagcc tctcgatgcc
     9661 gggggtgccc gggcgcacga ggaagacggt ggaaaccgcg acgatgccac ggttggagaa
     9721 gctgtggatg ctggcgcgca gctcggccag cgcgtcggcg tccatctcca tgctgccgcg
     9781 gatctcgagc aggtcgccga agcggcgatc ggccggcagg cggcggccgg ccaatgcgat
     9841 ggcgcgcttc acggcggcca tcagcccggc gtcgaagggg ccctcggcca tcgacaccat
     9901 cacgcggccg tgcacgccga cgctgacccg cccgaagctg gggcggatgc gtctgtggag
     9961 cggcggggcg gggatggggc gcatgggctt gcggaactgc tgcggcgatt ttgcaccgct
    10021 cgatgggcgc gtcatgccaa caggaagctt gcaggtaaaa agtggcgaag gccgccttcg
    10081 tgtccaatga tccgctccag aacccggagc cgcccatgac ccatcccatc gatgcctggc
    10141 atgaactggc caaggcccgc aacccgcgcg cgctggccgc gctgctggcc gaggacgtcg
    10201 tcttccactc gcccgtcgtg cacacgccgc agcgcggccg tgcgctcgcg acgcaatacc
    10261 tcgccgccgc gctggccgtg cttggcaacg agagctttcg ctatgtgcgc gagatccgcg
    10321 gcgagcgcga tgcgctgctg gagttcgagc tggagctggc cggcgtgcag gtcaacggcg
    10381 tggacatcat ccgctggaac gacgccggcc ggatcaccga cttcaaggtc atggtgaggc
    10441 cgctgaaggg catgcaggcc gtgcaacaga agatggccga gctgctggcg cagatgcagc
    10501 aacaacagca gcagtgatca gtccagcgtg cggcggtagc gcagcagcgc gacgccgccg
    10561 gccgcggcca ggaaggccag catcggccac agctccggca acagctcggc cgcgcccgag
    10621 cccttcagca tgacgccgcg cacgatgcgc aggaagtggg tcagcggcag cgcctcgccc
    10681 aggtgctgcg cccactgcgg catgccgcgg aaggggaaca tgaaacccga cagcagcatg
    10741 gacggcagga agaagaaaaa ggtcagctgc agggcctgga gctgattctt cgccagggtc
    10801 gagaacgtga agcccacgcc caggttgg
//
