LOCUS       NC_021505.1            10834 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021505.1 Pseudomonas putida NBRC 14164, complete sequence.
ACCESSION   NC_021505
VERSION     NC_021505.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:05:49
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3877299
            Orig. end    :: 3888133
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10834
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3882299:3883133](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5834)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10834
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10834
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(58..594)
                     /gene_functions="other (smcogs) SMCOG1241:lipoprotein dsbF
                     (Score: 115.4; E-value: 3.8e-35)"
                     /gene_kind="other"
                     /locus_tag="ctg1_3405"
                     /transl_table=11
                     /translation="MTIDGRLMLKVGSIALALSGLGLAGHLMARDSYGAMPSLSGASQW
                     INSPPLDGPALKGKVVLVDFWTWDCINCQRSLPHVNDWARRYADQGLVVVGVHTPEYDY
                     EHDVGTLRNKVAGLGVGYPVAVDNDHKVWNAWGNQFWPAHYFVDRKGQVRHVHFGEGDY
                     GGQEQVIKALLDERG"
     PFAM_domain     complement(130..429)
                     /aSDomain="AhpC-TSA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00578.23"
                     /description="AhpC/TSA family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3405_0217"
                     /evalue="2.40E-11"
                     /label="ctg1_3405"
                     /locus_tag="ctg1_3405"
                     /protein_end="155"
                     /protein_start="55"
                     /score="43.7"
                     /tool="antismash"
                     /translation="LKGKVVLVDFWTWDCINCQRSLPHVNDWARRYADQGLVVVGVHTP
                     EYDYEHDVGTLRNKVAGLGVGYPVAVDNDHKVWNAWGNQFWPAHYFVDRKGQVRH"
     CDS             complement(584..859)
                     /locus_tag="ctg1_3406"
                     /transl_table=11
                     /translation="MNLKTFASASLFAMLSFGAIAAQAAAMPTQNTGAMQYHYGEHLDV
                     KKVLSVQDDQSNACGLVNTRMDYLDSHGRPQSVEYRSYATGGCHDN"
     PFAM_domain     complement(596..826)
                     /aSDomain="DUF2790"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10976.10"
                     /description="Protein of unknown function (DUF2790)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3406_0218"
                     /evalue="2.00E-22"
                     /label="ctg1_3406"
                     /locus_tag="ctg1_3406"
                     /protein_end="88"
                     /protein_start="11"
                     /score="79.0"
                     /tool="antismash"
                     /translation="FAMLSFGAIAAQAAAMPTQNTGAMQYHYGEHLDVKKVLSVQDDQS
                     NACGLVNTRMDYLDSHGRPQSVEYRSYATGGC"
     CDS             complement(1121..1294)
                     /locus_tag="ctg1_3407"
                     /transl_table=11
                     /translation="MSQTYPSPAHRAHDRLCEQIEAFLQQGGHIQQVARGVSGSPDGVS
                     KLQWHKARTAKP"
     CDS             1565..2305
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 198.9; E-value: 1.3e-60)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3408"
                     /transl_table=11
                     /translation="MEHVDHILIVDDDREIRELVGNYLKKNGLRTSIVADGRQMRAFLE
                     ANSVDLIVLDIMMPGDDGLLLCRELRAGKHRNTPVLMLTARNDETDRIIGLEMGADDYL
                     TKPFSARELLARINAVLRRTRMLPPNLTISESSRLLRFGQWRLDTTARHLLDNDGTLVA
                     LSGAEYRLLRVFLDHPQRVLSREQLLNLTQGREADLFDRSIDLLVSRLRQRLGDDAREP
                     SCIKTVRSEGYVFSLPVQLLESPS"
     PFAM_domain     1583..1918
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3408_0219"
                     /evalue="2.10E-30"
                     /label="ctg1_3408"
                     /locus_tag="ctg1_3408"
                     /protein_end="118"
                     /protein_start="6"
                     /score="105.3"
                     /tool="antismash"
                     /translation="ILIVDDDREIRELVGNYLKKNGLRTSIVADGRQMRAFLEANSVDL
                     IVLDIMMPGDDGLLLCRELRAGKHRNTPVLMLTARNDETDRIIGLEMGADDYLTKPFSA
                     RELLARIN"
     PFAM_domain     2045..2269
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3408_0220"
                     /evalue="4.50E-20"
                     /label="ctg1_3408"
                     /locus_tag="ctg1_3408"
                     /protein_end="235"
                     /protein_start="160"
                     /score="71.6"
                     /tool="antismash"
                     /translation="LVALSGAEYRLLRVFLDHPQRVLSREQLLNLTQGREADLFDRSID
                     LLVSRLRQRLGDDAREPSCIKTVRSEGYVF"
     CDS             2302..3588
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 148.6; E-value: 5.5e-45)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3409"
                     /transl_table=11
                     /translation="MKWPRTLASRLAMIFFTGLVLAYGLSFGLQAYERYISSRSMMLSN
                     LEQDVATSVAILDRLPAAERAAWLPRLERRTYRYRLDQGLAGEAMASSDPPMAAASIVK
                     AIGSDYRLTFQEIPGPNAHFQAHLNLADGAPLTIDVTPAPVPVARWLPVVLLIQLAVLM
                     LCTWLAVHLAIGPLTRLAQAVDNLDPDQPGVQLDESGPREVRYAAVAFNALQARIAAHL
                     KERMQLLAAISHDLQTPITRMKLRVEVMDEGVEKDKFGSDLDEMEHLVREGVAYARSMD
                     SSTEATCRVNLDAFLDSLVFDYQDSGAQVERHGSSGALLETRPHALRRVLVNLVDNALK
                     FAGAAELQVSREGSTTIIRVLDNGPGIPGDELDEVLKPFYRVEGSRNRSTGGTGLGLAI
                     AHQLIQAMGGRLTLSNREQGGLCAQIELS"
     PFAM_domain     3274..3582
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3409_0221"
                     /evalue="2.00E-21"
                     /label="ctg1_3409"
                     /locus_tag="ctg1_3409"
                     /protein_end="427"
                     /protein_start="324"
                     /score="76.7"
                     /tool="antismash"
                     /translation="HALRRVLVNLVDNALKFAGAAELQVSREGSTTIIRVLDNGPGIPG
                     DELDEVLKPFYRVEGSRNRSTGGTGLGLAIAHQLIQAMGGRLTLSNREQGGLCAQIEL"
     CDS             3758..4279
                     /locus_tag="ctg1_3410"
                     /transl_table=11
                     /translation="MKAFTLPSDWKLSTALAGLTTVDRLGSWSADVPLRVFLAWEFFES
                     GLEKFNGSNWFADLQSSFPFPFNLLPAELNWQLSMWAELVLPLLLLLGLGTRLASLGLM
                     VVTVVAIAAVHWPAHWSGLAELAQGYAITDQGFGNYKLPLIYLVALLPLLLKGAGRLSL
                     DHWLGMRFGR"
     PFAM_domain     3851..4105
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3410_0222"
                     /evalue="3.10E-23"
                     /label="ctg1_3410"
                     /locus_tag="ctg1_3410"
                     /protein_end="116"
                     /protein_start="31"
                     /score="82.3"
                     /tool="antismash"
                     /translation="VPLRVFLAWEFFESGLEKFNGSNWFADLQSSFPFPFNLLPAELNW
                     QLSMWAELVLPLLLLLGLGTRLASLGLMVVTVVAIAAVHW"
     CDS             complement(4313..5008)
                     /locus_tag="ctg1_3411"
                     /transl_table=11
                     /translation="MNETLRAQQYALARHLRDPQRHAPPPGVEARRLKVYRELFYGAIE
                     GLLAGSFPVMRQVLGEQRWHARVRDFYASYRCQTPLFTEIAETFVDYLQRVALDAPWQL
                     ELAHYEWVEAQLYLSDAEDPAHDPGGDLLAGEPLLSCVARVLAYRWPVESIGVDYQPTA
                     APASPSLLLVYRDARLQVRFARLAPMAYRLLMEQGTGRERLQALGGDVQQGLVLLEALR
                     EQGVIVGTV"
     PFAM_domain     complement(4730..4987)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3411_0223"
                     /evalue="3.00E-23"
                     /label="ctg1_3411"
                     /locus_tag="ctg1_3411"
                     /protein_end="93"
                     /protein_start="7"
                     /score="81.9"
                     /tool="antismash"
                     /translation="QQYALARHLRDPQRHAPPPGVEARRLKVYRELFYGAIEGLLAGSF
                     PVMRQVLGEQRWHARVRDFYASYRCQTPLFTEIAETFVDYL"
     CDS             complement(5001..5834)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3412"
                     /sec_met_domain="DUF692 (E-value: 3.2e-119, bitscore:
                     395.4, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPAMLNIGLGLRRGLLPELLAMEAGAVDFLECAPENWIAVGGAY
                     GKGLAQLAERFAVTCHGLSLSLGGSAPLDRHFLEQTRQFLDRYQVRLYSEHLSYCSDDG
                     HLYDLMPIPFTDEAVHHVAARIRQAQEQLERRIAVENISYYAAPYQAMSELDFIRAVLE
                     EADCDLLLDVNNVYVNACNHGYDAQQFLAGLPPARVTGMHVAGHYDEAPDLKVDTHGAA
                     VKEDVWALYASACVRFGVKPTVLERDFNYPPLAELLAETARMRAVQCAAGGQADE"
     PFAM_domain     complement(5031..5813)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3412_0224"
                     /evalue="3.00E-102"
                     /label="ctg1_3412"
                     /locus_tag="ctg1_3412"
                     /protein_end="268"
                     /protein_start="7"
                     /score="341.4"
                     /tool="antismash"
                     /translation="IGLGLRRGLLPELLAMEAGAVDFLECAPENWIAVGGAYGKGLAQL
                     AERFAVTCHGLSLSLGGSAPLDRHFLEQTRQFLDRYQVRLYSEHLSYCSDDGHLYDLMP
                     IPFTDEAVHHVAARIRQAQEQLERRIAVENISYYAAPYQAMSELDFIRAVLEEADCDLL
                     LDVNNVYVNACNHGYDAQQFLAGLPPARVTGMHVAGHYDEAPDLKVDTHGAAVKEDVWA
                     LYASACVRFGVKPTVLERDFNYPPLAELLAETARMRAVQ"
     CDS             complement(5909..6400)
                     /locus_tag="ctg1_3413"
                     /transl_table=11
                     /translation="MTQAKNTLGLLGAALIGSMALSNSAFAVEPLAQGYQLASAKVAGE
                     GKCGEGKCGGSGKASQSEGKCGEGKCGAGAKAGAEGKCGEGKCGDASFAKTDSNHDGKV
                     SRDEFLAVAKDRAREFDTIDRNHDGFISEQEAADHLKAIYQANGKAMPDGLFSHLTGKP
                     "
     PFAM_domain     complement(5996..6046)
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3413_0226"
                     /evalue="1.20E-03"
                     /label="ctg1_3413"
                     /locus_tag="ctg1_3413"
                     /protein_end="135"
                     /protein_start="118"
                     /score="18.3"
                     /tool="antismash"
                     /translation="EFDTIDRNHDGFISEQE"
     PFAM_domain     complement(6065..6127)
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3413_0225"
                     /evalue="2.80E-04"
                     /label="ctg1_3413"
                     /locus_tag="ctg1_3413"
                     /protein_end="112"
                     /protein_start="91"
                     /score="20.3"
                     /tool="antismash"
                     /translation="SFAKTDSNHDGKVSRDEFLAV"
     CDS             complement(6575..7135)
                     /locus_tag="ctg1_3414"
                     /transl_table=11
                     /translation="MLVRSLTLATLLAVAGPLFAADSDAPLAKELGKARPLVVIAPSSA
                     DPTLRGLNKALEDPATQAAFKERNLVLYSVANMMGKREDKNLEQQTTMALIRELKLGAS
                     KGTKVILVGKDGERHMLKDDDTGEAIDPQVILKAVDELPASEKAVAAPEPVAAAPQAKD
                     KDSKPAKPAKPAKPAAPPKPLED"
     PFAM_domain     complement(6698..7060)
                     /aSDomain="DUF4174"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13778.8"
                     /description="Domain of unknown function (DUF4174)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3414_0227"
                     /evalue="1.80E-19"
                     /label="ctg1_3414"
                     /locus_tag="ctg1_3414"
                     /protein_end="146"
                     /protein_start="25"
                     /score="70.5"
                     /tool="antismash"
                     /translation="PLAKELGKARPLVVIAPSSADPTLRGLNKALEDPATQAAFKERNL
                     VLYSVANMMGKREDKNLEQQTTMALIRELKLGASKGTKVILVGKDGERHMLKDDDTGEA
                     IDPQVILKAVDELPASE"
ORIGIN
        1 aaaagtgttg gcttcttcgc ggcggttcgc cacctcgaag aggccgatac aggcgaatca
       61 cccgcgctca tccagcaacg cctttatcac ttgttcctgc ccgccataat ccccctcgcc
      121 aaagtgcaca tggcgcacct gccccttgcg gtcgacaaag taatgcgccg gccagaactg
      181 gttgccccag gcattccaca ccttatggtc gttgtccacc gccaccgggt aaccgacacc
      241 cagccctgcc accttgtttc gcagggtgcc cacatcgtgc tcgtagtcgt actccggcgt
      301 atgcacgccc accaccacca gcccctgatc ggcataacgc cgcgcccagt cgttcacatg
      361 cggcaggctg cgctggcagt tgatgcagtc ccaggtccag aagtccacca gcaccacctt
      421 ccccttcagc gctggcccat ccagcggggg cgagttgatc cactggctgg cccccgacag
      481 cgacggcatg gcgccataac tgtcacgggc catcaggtgc ccggccaaac ccagcccact
      541 cagcgccaac gcaatgctcc ccaccttcaa catcaagcgg ccatcaattg tcatggcaac
      601 cgccagtggc gtagctgcgg tactccacgc tctgcggccg gccgtgggag tcgaggtagt
      661 ccatgcgggt gttcaccagg ccgcaggcgt tgctctggtc atcctgcacc gacagcactt
      721 tctttacatc cagatgctca ccgtagtggt actgcattgc acctgtattc tgcgtcggca
      781 tggcggcagc ctgggccgca atggcgccga agctgagcat ggcaaacagg ctggcgctgg
      841 cgaaagtctt caagttcatg gcatctctcc tgtgtaacgc ttggctgtgg ggcgtgtttt
      901 ccccggtcga gagccatttg acgcctgcca tgtatcccgt ctgtgtcgct caacgctgtg
      961 ctgtgcgtcc tcctgtagct gcacgcctgt cggccaaacc tcgtgaaatc ctacaaaagc
     1021 ctttgcaagc aggtagttga aacaaagaag gcgcccacga agggcgccca gcttgtacaa
     1081 aggaatacaa tcggctcagg cgtttgcgga tgcttggcca tcacggcttg gcggtacgcg
     1141 ctttatgcca ctgaagtttg gatacgccat ccggggagcc gctgacaccg cgtgctactt
     1201 gctggatatg gccgccttgc tggaggaacg cttcgatctg ctcgcagagg cggtcgtggg
     1261 ctctatgggc tgggctgggg tatgtctggg acatgcaggc tactcggtaa tgagccactg
     1321 aaatacagtt acccgaggcg ccattgtacg cgctgtgctg cattcaggcg ctaaaccgga
     1381 gtaaaacccg gtttatatcg gcccggcggt ccatgctcac cgtttcgctg gctgcccgag
     1441 ccacccaaac caccgcatgc ggggtcatat gtccctgcca gatacactgc aatacaaacc
     1501 ccgcaggcaa gcgcaaacgc gccgggtaca ctgcgccaac cccactcgaa caggaacgct
     1561 gcgcatggaa cacgtcgatc acatcctgat cgtcgacgac gaccgcgaaa tccgcgaact
     1621 ggtcggcaac tacctcaaga agaacggcct gcgcaccagc atcgtcgccg acggccggca
     1681 gatgcgcgcc tttctcgaag ccaacagcgt cgacctgatc gtgctcgaca tcatgatgcc
     1741 tggcgacgac ggcctgctgc tgtgccgcga attgcgcgcc ggcaagcacc gtaacacccc
     1801 cgtgttgatg ctgacggccc gcaacgatga aaccgaccgc atcatcggcc tggaaatggg
     1861 cgccgacgat tacctgacca agccgttctc tgcccgcgaa ctgctggccc gtatcaatgc
     1921 cgtgctgcgc cgcacgcgca tgctgccacc caacctcacc atcagcgaaa gcagccgtct
     1981 gctgcgcttc ggccaatggc ggctggacac caccgcgcgc cacctgctcg acaacgacgg
     2041 caccctggtg gccctgagcg gcgccgagta ccgcctgttg cgggtgtttc ttgaccaccc
     2101 gcagcgggtg ctcagccgcg aacagttgct caacctgaca caaggccgcg aggccgacct
     2161 ctttgaccgc tccatcgacc tgctggtcag ccgcctgcgc cagcgcctgg gcgacgacgc
     2221 ccgcgagccc agctgcatca agaccgtgcg cagcgagggc tacgtgtttt cgctgccggt
     2281 gcaattgctc gagtccccct catgaaatgg ccgcgcaccc tggcctcgcg tctggcgatg
     2341 atctttttca ccggcctggt gttggcttat ggtctgtcgt tcggcctgca ggcctacgag
     2401 cgctatatca gcagccgctc gatgatgctc agcaacctcg aacaggacgt ggcgacttcg
     2461 gttgccatcc ttgatcgcct gcctgcagcc gagcgtgccg cctggctgcc acgcctggaa
     2521 cggcgcacct accgctatcg ccttgaccag ggcctggcag gcgaagcgat ggccagcagt
     2581 gacccaccga tggccgccgc gtcgatcgtc aaggccattg gcagcgacta ccgcctgacc
     2641 ttccaggaaa ttccggggcc caatgcgcac ttccaggcgc acctgaacct ggccgacggc
     2701 gcgcccctga ccatcgacgt gacacccgca ccggtcccgg tagcccgttg gttgcccgtg
     2761 gtgctgctga ttcagctggc tgtgctgatg ctgtgtacct ggctggcggt acacctggcc
     2821 atcggcccgc tcacccgact ggcccaggca gtggacaacc tcgacccgga ccaacccggc
     2881 gtgcaactgg atgaaagcgg gccacgcgag gtgcgttacg ctgccgtggc cttcaacgcc
     2941 ctgcaggcgc gcattgctgc ccacctcaag gaacgcatgc agttgctggc agccatttcc
     3001 cacgacctgc aaacaccgat cactcgcatg aagttacggg tcgaagtgat ggatgagggg
     3061 gtcgaaaagg acaagttcgg aagcgacctg gatgaaatgg aacacctggt gcgcgaaggc
     3121 gtggcttacg cccgcagcat ggacagcagc accgaagcga cctgccgggt caaccttgat
     3181 gcctttctcg acagcctggt attcgactac caggacagcg gcgcccaggt tgaacgccac
     3241 ggcagcagcg gtgccctgct ggagacccgc ccgcatgcgc tgcgccgggt actggtgaac
     3301 ctggtcgaca acgccctgaa gtttgcaggt gctgccgagc tgcaagtatc acgcgagggc
     3361 agtaccacca taatccgcgt gctcgacaac gggccgggga tacccggtga cgagctggat
     3421 gaagtgctca agccgttcta ccgtgttgaa ggttcacgca atcgcagcac gggtggcacc
     3481 ggcctgggac tggccattgc ccaccagttg atccaggcca tgggggggcg gctgaccctg
     3541 agcaaccgcg aacagggcgg attgtgcgcg cagatcgaac tctcctgaag tgcatctgcg
     3601 atcgttggca ggaacggcct tggatctgga tcgggccgtt cctgtaaaac gcgaggtcgc
     3661 ctctacaaac agatacacaa ctgcatcccc ctgacacact gcagataccc cgcctcgaca
     3721 cactcccggt cacacaacca caccccggga gtccctgatg aaagccttca ccttgccctc
     3781 cgactggaag ctgtccaccg ccctcgccgg cctgaccacc gttgatcgcc tcggtagctg
     3841 gagtgccgac gtgccattac gggtatttct ggcctgggag tttttcgaat ccggtctgga
     3901 aaaattcaac ggcagcaact ggttcgccga cctgcagtcc agcttcccgt tccccttcaa
     3961 cctgctgccc gcggagttga actggcagct gtcgatgtgg gccgagttgg tgctgccgtt
     4021 gctgctgctg ttgggcctgg gtacccggct ggcatcgttg ggtttgatgg tggtaaccgt
     4081 tgtagcgata gcggcagtgc actggccggc gcactggtcg ggcctggcgg agctggccca
     4141 aggctatgcc attaccgacc agggcttcgg caattacaag ttgccattga tctacctggt
     4201 ggcgttgcta cccctgctgc tcaagggcgc cgggcgcctt agcctcgatc attggcttgg
     4261 catgcggttc ggcagatgag ggtcgggggc tgctgagcag cccccaatgc cttcaaactg
     4321 ttccgacaat gacgccctgc tcgcgcaatg cctccaacaa taccaaccct tgctgcacat
     4381 ccccgcccaa tgcctgcagc cgctctcttc cagtcccctg ctccatcagc aaccgatacg
     4441 ccataggtgc caaccgggca aaacgcacct gcaaccgggc atcgcgataa accagcagca
     4501 agctcggcga tgctggggca gccgttggct ggtagtccac gccaatgctt tccaccggcc
     4561 aacgataggc cagcacccgc gccacacaag acaacaacgg ctctcccgcc agcaggtcac
     4621 cacccggatc atgcgccggg tcctcggcat cgctcaggta cagttgcgcc tcgacccact
     4681 catagtgcgc cagctccagc tgccaagggg cgtccagcgc tacacgttgc aagtagtcga
     4741 cgaacgtctc ggcaatttcg gtaaacaacg gcgtctggca acggtaactg gcgtagaaat
     4801 cacgtactcg ggcgtgccag cgctgctcgc ccaacacctg gcgcatgacc gggaagctgc
     4861 cagccagcaa cccttcgatg gcaccataga acaattcacg gtaaaccttc aggcgccggg
     4921 cttcgacgcc gggcggcggg gcatggcgtt gtgggtcgcg caggtgacgg gccaaggcat
     4981 actgctgcgc acgcagggtc tcattcatct gcttgccctc cggcagcgca ttgcacagca
     5041 cgcatacgcg ccgtctcggc caacagttcg gccaagggcg ggtagttgaa atcccgttca
     5101 agcaccgtcg gctttacacc aaagcgcacg caagcgctgg cgtacagggc ccagacatcc
     5161 tccttcacgg ctgccccgtg ggtatccact ttgaggtccg gcgcttcatc gtaatgcccg
     5221 gcaacgtgca tcccggtcac tcgcgccggg ggcaagcctg caaggaattg ctgggcgtcg
     5281 tagccatggt tgcaggcgtt gacataaaca ttgttgacgt ccagcagcag gtcacaatcc
     5341 gcttcttcga gcaccgcccg gatgaagtcg agttcgctca tcgcctgata cggcgcggcg
     5401 tagtagctga tgttctccac ggcaatgcgc cgctccaact gctcctgagc ctgacgtatg
     5461 cgcgcggcca catggtgtac ggcttcatcg gtgaacggga tgggcatcag gtcgtacagg
     5521 tgcccgtcat cactgcagta gctcaggtgc tcgctgtaca gccgcacctg gtaccgatca
     5581 agaaactgcc gggtctgctc aaggaaatgg cggtccagcg gcgcactgcc acccagcgat
     5641 aaagacaacc catgacaggt gacagcaaag cgctccgcca actgggccaa gcccttgcca
     5701 taggcaccgc ccacggcaat ccagttttcc ggcgcacact cgagaaagtc cactgcaccc
     5761 gcctccatgg ccagcagttc gggcaacagg ccacgacgca agcctaaccc gatgttcaac
     5821 atcgcaggaa acataaaagt tctccaacca gcacaacgcc ccacctggcc agcaggagga
     5881 gcgttgtggc gtctcatggg gtagaaagtc agggcttgcc ggtcaggtgg ctgaacaacc
     5941 catcaggcat ggctttgcca ttggcctgat aaatcgcctt gaggtgatcc gccgcttcct
     6001 gctcggagat gaagccgtca tggttgcggt cgatcgtgtc gaactcacgg gcacggtcct
     6061 tggccaccgc cagaaactca tcgcgcgaga ccttgccatc gtgattgctg tcggttttgg
     6121 cgaacgaggc gtcaccgcac ttgccttcac cacacttgcc ctcagccccg gccttggcgc
     6181 cggcgccgca tttaccttca ccgcacttgc cttcgctttg ggaagccttg ccgctccccc
     6241 cgcacttgcc ttcaccacac ttgccctcgc cggccacttt ggccgaggcc agttggtaac
     6301 cttgagccag cggctcgacg gcgaacgcac tgttgctcaa tgccatgctg ccgatcaggg
     6361 cggcgccgag caggccgagg gtgttttttg cttgagtcat gatgcagctc cactggggtt
     6421 ggaaagtgga gccattaggc cgttgcggtt tgtcgtggat gtatcgtggc aggcgcactt
     6481 ttgtatggca gtaggtctgc agcacaggca gatacagtgc gatacacacc acccggcgac
     6541 gggccccaag gtgccttggg gccctgaggc gtgatcagtc ttccagcggt ttgggcgggg
     6601 ccgctggctt ggcgggcttg gcaggcttgg ccggcttgct gtccttgtcc ttggcttgcg
     6661 gggccgcggc tacgggctcg ggcgccgcca ccgccttttc gctggcaggc agttcatcga
     6721 ccgctttgag gatcacctgt gggtcgatgg cctcgccggt gtcgtcgtcc ttgagcatgt
     6781 gccgctcacc gtccttgccc accagaatca ccttggtccc cttgctcgca cccagcttca
     6841 gttcccgaat gagggccatt gtggtctgct gctcgaggtt cttgtcctct cgcttgccca
     6901 tcatgttggc gacgctgtac aggacaaggt tgcgctcctt gaacgcagcc tgggtggccg
     6961 ggtcctcgag cgccttgttc agccctcgca acgttgggtc ggcactgctg ggagcgataa
     7021 ccaccaatgg tctggccttg cccagttcct tggctagagg cgcatcactg tctgcggcaa
     7081 acagggggcc ggcaacagca agcaaggttg cgagggtcag tgaccggaca agcatgcgta
     7141 tctccttatt gtctcgatat accaatgact acagatcacg gagaaaaatc cgacagggag
     7201 cctaaaccac ttcattccag aacggggtgt gcaaaagtaa ctgtcgattt ccgagccacc
     7261 tgaagccaag actacggcgc tgctacaaac cactgtcagc acgattgagc atagcccaaa
     7321 gccgctttgg cagggccagg cagcccgtga tctgagcgca ggtcaacgca catcgatcgc
     7381 tggccccttg gggccgactt ccatcgcgtg aatcgtcata tccagcatca gccctctgcg
     7441 ggcagcgcgc tgagcatcac gaatggcatc cgcctggtcg atcatggccc cttcggtcag
     7501 tgcttcgtcg tcaagcacgg tttcaagctg ccttctgaac ggcaggtcga ccgcagcgaa
     7561 tcgctcagga tgggaacgct ccaggtgcgc ctgccagaat tcacggtcga ccatggagcg
     7621 ggcaatctct tccggcgttt ctgcatcccg caccgcagcc tctgcttctg caaggtccgc
     7681 atccaggacg cccgagatcg caagaaagct catttcgccc acctgcaatg gcaggtcgag
     7741 acgctccctc agcccgaccc tgaaagccaa ccccacctcg cttccttcca gcgtcctgcc
     7801 atgctgtaac gcccatcggg tagcgaacat gtcgactgca tcctggcgcc ataaacgtct
     7861 gcccaggtct agcaaagcgc gttcgcttcc tcccttggcc gcgtgctcaa cctgccaaac
     7921 cagcaaattc agttcaaggt tgctcaagca ccaggttgca ccatcctggc acccccactc
     7981 atcattggcc acggacagca agttctgccg aagctccggc gtaatggcca tcgcttgtaa
     8041 tacccccatt acccgattgc ccagtgcacg cggattgaca cgaaagtctt ctgacagcaa
     8101 taactggcga agcacacgga aaaaacgctc ggcgtcctgc cctgaatcca gcgagtccca
     8161 ggcagcaagc atcaagccgc gatgctccgg ggccacacta tccccccaga cttcacgcgc
     8221 gtgctgcagc cgcagaagca cttgctcctc gtcgagggca ggatcgtcgc tacttaacga
     8281 agcttgcaag cgtaacgtct gggcctcgcc caaagggttc gcattcaagc gaaaccgccg
     8341 cctatgccac aggggcaact ggtagaaacc ctctggaatg tgcctgatcc ggttatcccg
     8401 caagtcaacg gataccaact gagcgttgtc gaacacgccc agtggaaact gcgagatctg
     8461 cgtgtcgcgc aagctcagcc aacgcaattc agccaaaccc gccaacgtga accgcctccc
     8521 cagggggtta tgggaaaggt cgagagactg caggctcgtg caactggcca atgtggcggt
     8581 ctgtgcagtg ttcaggacga tgcggttgtt ggtcaggctc agatgccgca gctgcgttat
     8641 ctgtagcaac ggctgcggaa ggcgcgtcaa caggttccct cccagatcga gggtttgcag
     8701 gttagggaaa gccagcaata agctgctggg cacctccaga aggtcaaggt gcagcagcga
     8761 caggctggtc acacctctga aactgacctg tgcgggtatg ttaggcaagc cactcgatct
     8821 gaaattgcag aacatgacgt ggaggttttc ctgtgcattg atttgcagtt cccccacgcc
     8881 caccgaccgc cgccagcaat tgaacaacgt ctggcgtaaa gcctctcgat cttccctgac
     8941 atcgccctgc cctcgtgcca cccaggtatt cagtgtgatg cggagcaccg cgaactcatt
     9001 gcgaaggtca gccagtactt gttcaatctg atgcccggaa cgcctggcgt catcggcgaa
     9061 ggtctcgacc tgctcatcac tcaaccacgg aaagagatcg cgcagcgtcg ccctcagggc
     9121 acgccccctt gatgcaaaac cacctactcc gccgcccccc agtgggtagc caatacgtcc
     9181 atcggccaag cgcatgggcc ctcggacagc accggggcgt accgcgccaa gcaaacgact
     9241 gatctcatca cgatggcgtg ccgcttcgcg cgccactatc accctgaggt tgtgcgcaaa
     9301 gggatcgccg atccccatcg cctccctctg cgcttcggta taggctggcg cgatgacttc
     9361 gaacaactca cctgcctcac ccagcgccgt gccctggctg ccatgcagtt gaaacgtacc
     9421 gttcaggtgg accagatcga acgcccgctg cccttgctcg gtcttcgcca gtatcggccc
     9481 gcccaggcaa ccttcataca gacgccagca cacaccttgt tcgccaccgg gtacataccg
     9541 cagcaagccc aacgtcaccc gtgccaggtc tgcatgctgc ggcgtatcaa ggtacaacgc
     9601 ctcaaatacc cgagcctggc gggtagccag cacactgccc cttgccgcct cggccaaccc
     9661 cagtgcaacc cttgcgctgg actgcagccg catgcgatcc acgctgctgg cggcctgtac
     9721 caatgcttgc gcagtgcgcg cgctcagccc cgggaagacc cggcgcagcg ccgcgctgcc
     9781 aggggtgtcg ctgggctgca aggcttcgaa aaggtgctgc agcagtgttc ggcgctgcgt
     9841 ccatgccagc gcggccagtg cctgatctgt caggccactc gcgcctggca agtgccgagc
     9901 gtgatcgagc actgttgcat cttctaccgg ctcgccgttg cgcaggcggc caatcatgct
     9961 gcggatgcgt tgatcaagcc tgacccgctc cacactgtcg atcatcccgg ggctcggtgc
    10021 ctgggcgtgt acatgcaggc cacgcacgtc atcgccatca aggccatgga acagcagaac
    10081 ctgatcgatc tgttcgtcat tcagcccatt gaagggttca cccaaacgcc ggaacatgcg
    10141 gtatttgtcg gtccaccggg ccggttgctc gctccacaac cgccaggcac ctgcgccatt
    10201 gtggcgcagc aacggcccgt ggccgtcgac cggatacaac tgccattgat catcacccgc
    10261 ctctgccacg cgatagtgat gcccgtccat ttcgacccag gcctgcccgt cctggcgccg
    10321 aatacccaag gcatcccggc tcgaggccgc aacgggggcc tggctttgaa acggggtcaa
    10381 gtcgtgttgc cagagtttct cggtgccgtc ctccagccga gccggcacca tggcatcgac
    10441 ctgcgcagag cgtgcccaaa cccgtcgagc gacaccaacc ccggctaccg tggtggccag
    10501 cacggcaagg tctgtcgcca cgtgggtcaa atggtcgagc gcctcctggc tatcgccttc
    10561 ctgccaggcc tcggcgccat ggtagacctc acccagtagt tcgcaggccg tcacggccaa
    10621 cagcgccagg ccaagcccag gcaggaagaa actggccagg ttgagcagcg cccacccttc
    10681 ggcttcaagg cgcaggtcat gctggcgctg aacctcacga tccagtctgg ccacagggac
    10741 cgcgatcatc gccgcatctt ccttgatctg gtggatacgt gcctgtgcca ggctgatgaa
    10801 caatggctgc gggtaagcct gcaagtgcgg ttcg
//
