LOCUS       c00003_NZ_CYXV..       20727 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CYXV01000003.1 Roseburia faecis strain 2789STDY5608863, whole
            genome shotgun sequence.
ACCESSION   NZ_CYXV01000003
VERSION     NZ_CYXV01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:58:14
            Original ID  :: NZ_CYXV01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 188354
            Orig. end    :: 209081
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20727
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[198354:199081]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10727
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20727
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20727
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="3"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             686..1699
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_177"
                     /sec_met_domain="PF04055 (E-value: 9.2e-15, bitscore: 49.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2e-14, bitscore: 48.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.1e-13, bitscore:
                     44.5, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVGYMIWLTTACNLKCKYCYEGTAKVNCYLSKDYAAKIVDYIVQ
                     DCDKTKNLQISFHGGEPFLNYKIMEFISLELENQLHSVVNDISYQVTTNATILNEEIIE
                     FLKDHKIEVTCSLDGTKETHDSIRVFEENKGSYDIAMKNSLKLLALYPDLRVRMTVRST
                     EVENLSKNIIYLVEKGFNLIVPVLDFYDKNWNEEKFEIIKEEIKKVKIYVRNKDVTISL
                     LEPLSIKKKSLCQGGIQTINIYPNGDIYPCTLAAGDKEFLIGNIEQGINYKKLEEILSY
                     SQKENKECRGCVFYNFCNSTRCKIINKLVTGDYNSPNSLECNMNHLLYEENGYLCY"
     PFAM_domain     707..1060
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_177_0073"
                     /evalue="2.60E-12"
                     /label="ctg3_177"
                     /locus_tag="ctg3_177"
                     /protein_end="125"
                     /protein_start="7"
                     /score="47.5"
                     /tool="antismash"
                     /translation="WLTTACNLKCKYCYEGTAKVNCYLSKDYAAKIVDYIVQDCDKTKN
                     LQISFHGGEPFLNYKIMEFISLELENQLHSVVNDISYQVTTNATILNEEIIEFLKDHKI
                     EVTCSLDGTKETHD"
     aSDomain        1385..1651
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_177_0015"
                     /evalue="3.80E-12"
                     /identifier="TIGR04085"
                     /label="ctg3_177"
                     /locus_tag="ctg3_177"
                     /protein_end="322"
                     /protein_start="233"
                     /score="44.5"
                     /tool="antismash"
                     /translation="CQGGIQTINIYPNGDIYPCTLAAGDKEFLIGNIEQGINYKKLEEI
                     LSYSQKENKECRGCVFYNFCNSTRCKIINKLVTGDYNSPNSLEC"
     CDS             1780..1941
                     /locus_tag="ctg3_178"
                     /transl_table=11
                     /translation="MKIRKMENKELKKVVGQCCCKIVGKPSVYETDSCCLADCKKDGRD
                     TAHYTIYH"
     CDS             1954..2115
                     /locus_tag="ctg3_179"
                     /transl_table=11
                     /translation="MKIRKMENKELKKVTGQCCCKIVGKPSVYETDSCCLADCKKDGRD
                     TAHYTIYH"
     CDS             2541..3569
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 77; E-value: 2.9e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_180"
                     /sec_met_domain="Peptidase_S8 (E-value: 7e-12, bitscore:
                     39.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFIKKMRKVTIAIIDSGIDNRFKNQFKCKVSGIGVTLINNEIKI
                     VEDYFDENGHGTLTASVIINECPDIEFFIIKILDRKLEGNIECLIASLEYLLDKDVNII
                     NMSLAVEKNGRDSRLKKICKRLNDQGKILIAAVENGSKKSIPAIYSTVIAVEGRKLKQN
                     FDFMFSSNKRINCVIRSEPHLYYQKKDDYVMYGDCNSFAAAKLSGKLARILRKQPSNDN
                     SKVKKLLRKESKLFVWTVPLLNLFKEYPVFRDNNIIYDPIKLNKLATNIAVFFSVENIS
                     DIYSYSLYSSKISQKKEFAYRFLRFLEEKYGFVCENYSVFERNDFISIYSVYKFLKERY
                     KW"
     PFAM_domain     2562..3233
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_180_0074"
                     /evalue="2.30E-14"
                     /label="ctg3_180"
                     /locus_tag="ctg3_180"
                     /protein_end="231"
                     /protein_start="7"
                     /score="53.4"
                     /tool="antismash"
                     /translation="RKVTIAIIDSGIDNRFKNQFKCKVSGIGVTLINNEIKIVEDYFDE
                     NGHGTLTASVIINECPDIEFFIIKILDRKLEGNIECLIASLEYLLDKDVNIINMSLAVE
                     KNGRDSRLKKICKRLNDQGKILIAAVENGSKKSIPAIYSTVIAVEGRKLKQNFDFMFSS
                     NKRINCVIRSEPHLYYQKKDDYVMYGDCNSFAAAKLSGKLARILRKQPSNDNSKVKKLL
                     RK"
     CDS             3563..5266
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 279.5; E-value:
                     9.4e-85)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_181"
                     /transl_table=11
                     /translation="MVEFKEYVIYIFKENKIKSLIVFVLTLVVTTLSLLEPQLLVILVD
                     KAISHDNFNLLFIVSISYVILIVISALCKYSITVLRTKIKKQTTYKMRTKLLLHIQELP
                     GKYFTEQKTGDILKVIDSDVSALEETGIDFVIDIIKNLLSAISAFVILACINTKLLLIM
                     ILMETFMLFLHEKYIKLVSKKLERVRDISGKSMNLLEEFVVHMMDIIITHANILFLKKY
                     LNNEQLYINESTKLEKMIEKNQLTANTLNEIMFIVIYLISGLSIIQNTMTIGTMMAFIQ
                     YTSMLISPILQLTNSNTRIHIAIVSLRRIRTVLRIPKTVDVGTKENIEGKIQFENVNFS
                     YQPEVNVLNDFNMKIEKGKKIAIVGCSGCGKSTLLKLLYRLWSPNQGKILIDDIPIEKY
                     SLKALRDSIAIVTQDVMIFNDTVLNNINLTGDRNISEIKKMCKKIDLEDNAILMDENPE
                     GTVGEYGVKLSGGQKQRIAILRAILQNASIYVFDEATSALDNLTQEKIMEEIDTYLCGK
                     TTIIIAHRLSTVRNADYIYVIENGSVVEEGTHDKLMLKNGAYKKMYMSEI"
     PFAM_domain     3620..4429
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_181_0075"
                     /evalue="2.70E-19"
                     /label="ctg3_181"
                     /locus_tag="ctg3_181"
                     /protein_end="289"
                     /protein_start="19"
                     /score="70.0"
                     /tool="antismash"
                     /translation="LIVFVLTLVVTTLSLLEPQLLVILVDKAISHDNFNLLFIVSISYV
                     ILIVISALCKYSITVLRTKIKKQTTYKMRTKLLLHIQELPGKYFTEQKTGDILKVIDSD
                     VSALEETGIDFVIDIIKNLLSAISAFVILACINTKLLLIMILMETFMLFLHEKYIKLVS
                     KKLERVRDISGKSMNLLEEFVVHMMDIIITHANILFLKKYLNNEQLYINESTKLEKMIE
                     KNQLTANTLNEIMFIVIYLISGLSIIQNTMTIGTMMAFIQYTSMLISP"
     PFAM_domain     4604..5050
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_181_0076"
                     /evalue="4.70E-32"
                     /label="ctg3_181"
                     /locus_tag="ctg3_181"
                     /protein_end="496"
                     /protein_start="347"
                     /score="111.5"
                     /tool="antismash"
                     /translation="LNDFNMKIEKGKKIAIVGCSGCGKSTLLKLLYRLWSPNQGKILID
                     DIPIEKYSLKALRDSIAIVTQDVMIFNDTVLNNINLTGDRNISEIKKMCKKIDLEDNAI
                     LMDENPEGTVGEYGVKLSGGQKQRIAILRAILQNASIYVFDEATS"
     CDS             6915..7289
                     /locus_tag="ctg3_182"
                     /transl_table=11
                     /translation="MESRIKQLRENRGLIQEILASELGITQQMLSKYERDVLCIKVDVL
                     KRIAEYFNATTDYLLGVSEVKRDLQGQMKVNKTLDTYYDLIEIYKGLDEYDQEMVWSIM
                     QTVKKAGEKRKRDRENTEES"
     PFAM_domain     6927..7091
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_182_0077"
                     /evalue="1.40E-13"
                     /label="ctg3_182"
                     /locus_tag="ctg3_182"
                     /protein_end="59"
                     /protein_start="4"
                     /score="50.7"
                     /tool="antismash"
                     /translation="IKQLRENRGLIQEILASELGITQQMLSKYERDVLCIKVDVLKRIA
                     EYFNATTDYL"
     CDS             7296..8024
                     /locus_tag="ctg3_183"
                     /transl_table=11
                     /translation="MLNIAICDDDIQTTGRMDMLLQKIAKRNFMDVEIEVFWNGKSLAD
                     AVAKGTYFDMIYLDIEMDKEDGISAAKRIRAYDKNVLIIYVTSHENHMQESFEVRPFRF
                     LVKPVSEKQIESCFKSAYEEVYCGDSYFRYSYQRVNHKIPIREILYFESNKRKVFIVTE
                     KDTFVAYGKLNDIEESLKQSKVPFLRVHQSYLVNYKHVEGQAYDFVVMDNGKRISISED
                     RRKLIGEQYCSMEDTFYVNE"
     PFAM_domain     7305..7640
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_183_0078"
                     /evalue="2.30E-14"
                     /label="ctg3_183"
                     /locus_tag="ctg3_183"
                     /protein_end="115"
                     /protein_start="3"
                     /score="53.6"
                     /tool="antismash"
                     /translation="IAICDDDIQTTGRMDMLLQKIAKRNFMDVEIEVFWNGKSLADAVA
                     KGTYFDMIYLDIEMDKEDGISAAKRIRAYDKNVLIIYVTSHENHMQESFEVRPFRFLVK
                     PVSEKQIE"
     PFAM_domain     7716..7976
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_183_0079"
                     /evalue="1.20E-17"
                     /label="ctg3_183"
                     /locus_tag="ctg3_183"
                     /protein_end="227"
                     /protein_start="140"
                     /score="64.0"
                     /tool="antismash"
                     /translation="HKIPIREILYFESNKRKVFIVTEKDTFVAYGKLNDIEESLKQSKV
                     PFLRVHQSYLVNYKHVEGQAYDFVVMDNGKRISISEDRRKLI"
     CDS             8011..9318
                     /locus_tag="ctg3_184"
                     /transl_table=11
                     /translation="MSMSKTLSYGVDILFIIFAAYLFFCYFDIFLKRRKRTVLSVVGLV
                     AFMAWQFEMSSVNLLPAYGNIIITSITTLFAVAQTYEGKFWNKCIFTIAFNAIWMLMET
                     LSNYMLMTYCEQYAESEALGSVTSKLIFLIIIVALKKVFTDDEIKELPVRYSIMFVLIP
                     TGSIYIMNNIFMLGYKVHSNRASFHSAITAVILLFMNILIFYIYMKLADDLQLRRITSV
                     YEQQLDLCERHQQERELSILQLRDVRHNMKNNLVSILAYAENGDNEKIIGFVNEIMEEG
                     GIKTSAVTNSGNIVIDSLIGYWYVAAKKAGIEFSVNLNIPMEMPFRGADICLILGNLLE
                     NAVEATQRAEGEKYIRLHMKYDKNNLLLFVENNYKGVLIKTKDKRLKSTKTDAGNHGVG
                     IPSVYRIAAKYHGVVTIDDNVANRFLIRVVLYGKQK"
     PFAM_domain     8995..9300
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_184_0080"
                     /evalue="2.10E-23"
                     /label="ctg3_184"
                     /locus_tag="ctg3_184"
                     /protein_end="430"
                     /protein_start="328"
                     /score="82.2"
                     /tool="antismash"
                     /translation="ADICLILGNLLENAVEATQRAEGEKYIRLHMKYDKNNLLLFVENN
                     YKGVLIKTKDKRLKSTKTDAGNHGVGIPSVYRIAAKYHGVVTIDDNVANRFLIRVVL"
     CDS             9439..9840
                     /locus_tag="ctg3_185"
                     /transl_table=11
                     /translation="MMEVLLFSNDEKIFNLTNSVIDGRYKLTWCTYKSLEKKTCPYPYP
                     DIVIMHFDKEMVKKGTFKTIVQVKGRLGQRIPILALMEEGTPQNIFSTLIAGAYDYLEI
                     VKNSKEYKKKIEDAIRWNWYLGKYGLREK"
     CDS             10001..10150
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_186"
                     /sec_met_domain="TIGR04223 (E-value: 6.7e-17, bitscore:
                     55.2, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKKVKNQSAKVLANVSLKLGKMSADSACCYIYHQPKMPEALKK
                     MKNI"
     aSDomain        10028..10135
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg3_186_0016"
                     /evalue="1.20E-15"
                     /identifier="TIGR04223"
                     /label="ctg3_186"
                     /locus_tag="ctg3_186"
                     /protein_end="45"
                     /protein_start="9"
                     /score="55.2"
                     /tool="antismash"
                     /translation="SAKVLANVSLKLGKMSADSACCYIYHQPKMPEALKK"
     CDS             10152..10727
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_187"
                     /sec_met_domain="AgrB (E-value: 1.4e-34, bitscore: 113.0,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYFSEKLTGYIVKSGAVPEESYEIYQYGFQIGLEMLSCLLACFG
                     IAVYLHMIPEFAVVTGIFMMLRSFVGGVHLNSFSACFMCSVTVQTLVLVVNRLYTQPLN
                     AAWGIIVLSSILIWNMAPVQSINRELDADEKRHCRKVAVKIIAGIYVFAGICTLTGMKA
                     IVSLVAVTMAVVLISQYIGVVKYKIEKR"
     PFAM_domain     10164..10694
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_187_0081"
                     /evalue="1.50E-32"
                     /label="ctg3_187"
                     /locus_tag="ctg3_187"
                     /protein_end="181"
                     /protein_start="4"
                     /score="112.6"
                     /tool="antismash"
                     /translation="SEKLTGYIVKSGAVPEESYEIYQYGFQIGLEMLSCLLACFGIAVY
                     LHMIPEFAVVTGIFMMLRSFVGGVHLNSFSACFMCSVTVQTLVLVVNRLYTQPLNAAWG
                     IIVLSSILIWNMAPVQSINRELDADEKRHCRKVAVKIIAGIYVFAGICTLTGMKAIVSL
                     VAVTMAVVLISQYI"
     CDS             10978..11181
                     /locus_tag="ctg3_188"
                     /transl_table=11
                     /translation="MEQSSFYDETTVRHQFDRKCKLALDDEVVDYDRHMDYRRKNEVLF
                     SKLSECQAGEFSVLDEYNLEIY"
     CDS             11497..11751
                     /locus_tag="ctg3_189"
                     /transl_table=11
                     /translation="MTFNKAKAEKQWLKWKETEEEKLRQLGMDEESIRKLRQMDWEDFK
                     EERRYWEHFVESRGEATGEKRSFLIKTLIEGKECGNEIR"
     CDS             11809..12729
                     /locus_tag="ctg3_190"
                     /transl_table=11
                     /translation="MKKIKEYAERGYTHAVALDLSKYFDTLNHEKLLNLLRRDIKDERV
                     IQWIKRYLKSGVMENGVVMETEEGSPQGGNISPLLANIYLNEFDQEYEKRGVKFVRYAD
                     DIVLLAKSDRAAKRLLETSTKYLEGTLKLKVNQEKSRVVSVFAIRNFKYLGFTLGKNGK
                     GIYIRVHGKSWKKMKSKLKELSSRRSCQSIRPSLQEIKEYMRGWLNYYGVADMKKKIDD
                     LNKWLYHRIRMCIWKQWKKPKTKIRNLLKMGVPKDLAWQAGNSRRGYWFVTHTIAVNLA
                     MTKERLINSGFYDLATAYQSVHVNY"
     PFAM_domain     11818..12282
                     /aSDomain="RVT_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00078.29"
                     /description="Reverse transcriptase (RNA-dependent DNA
                     polymerase)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_190_0082"
                     /evalue="6.90E-32"
                     /label="ctg3_190"
                     /locus_tag="ctg3_190"
                     /protein_end="158"
                     /protein_start="3"
                     /score="110.9"
                     /tool="antismash"
                     /translation="IKEYAERGYTHAVALDLSKYFDTLNHEKLLNLLRRDIKDERVIQW
                     IKRYLKSGVMENGVVMETEEGSPQGGNISPLLANIYLNEFDQEYEKRGVKFVRYADDIV
                     LLAKSDRAAKRLLETSTKYLEGTLKLKVNQEKSRVVSVFAIRNFKYLGFTL"
     PFAM_domain     12331..12552
                     /aSDomain="GIIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08388.13"
                     /description="Group II intron, maturase-specific domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_190_0083"
                     /evalue="5.10E-14"
                     /label="ctg3_190"
                     /locus_tag="ctg3_190"
                     /protein_end="248"
                     /protein_start="174"
                     /score="52.2"
                     /tool="antismash"
                     /translation="KKMKSKLKELSSRRSCQSIRPSLQEIKEYMRGWLNYYGVADMKKK
                     IDDLNKWLYHRIRMCIWKQWKKPKTKIRN"
     CDS             12983..14164
                     /locus_tag="ctg3_191"
                     /transl_table=11
                     /translation="MKWKGRRLLAMALTGILLAGCGAAGQVDDYATNEGSTQEASTKTT
                     GTESGGISKDKIRVGVLHLSDPAEGSGYTYTHDLGIQAMQQNLGLSDEQIDRKINVDDS
                     DKEATEKAIQECVDDGCNIIFTTSWGYMDATEEMAEKYPDIYFAHGTGYKSNGKNFVNY
                     FGRIYQARYLSGIVAGMNTKTDKLGYVAAMDSSNSEVTGGIDAFALGVYSVNPDAKIYV
                     KVTNSWFDPDAEKAAAQTLLNMDCDVVTQHCDTEYPQTMAQEKGVYGIGYNSDMSKNAP
                     DACLCSVIWNWGAYYTAAVQSVIDGTWDGSNYYGGMNENLVGITSLADFCTDGTQEAVD
                     TAKEDILSGKNGVFDGVIETNTGETVGEEGKTLDDATITGGINWYFKTVEVVE"
     PFAM_domain     13163..14014
                     /aSDomain="Bmp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02608.16"
                     /description="ABC transporter substrate-binding protein
                     PnrA-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_191_0084"
                     /evalue="4.80E-49"
                     /label="ctg3_191"
                     /locus_tag="ctg3_191"
                     /protein_end="344"
                     /protein_start="60"
                     /score="167.0"
                     /tool="antismash"
                     /translation="VLHLSDPAEGSGYTYTHDLGIQAMQQNLGLSDEQIDRKINVDDSD
                     KEATEKAIQECVDDGCNIIFTTSWGYMDATEEMAEKYPDIYFAHGTGYKSNGKNFVNYF
                     GRIYQARYLSGIVAGMNTKTDKLGYVAAMDSSNSEVTGGIDAFALGVYSVNPDAKIYVK
                     VTNSWFDPDAEKAAAQTLLNMDCDVVTQHCDTEYPQTMAQEKGVYGIGYNSDMSKNAPD
                     ACLCSVIWNWGAYYTAAVQSVIDGTWDGSNYYGGMNENLVGITSLADFCTDGTQEAVDT
                     AKE"
     CDS             14174..15874
                     /gene_functions="other (smcogs) SMCOG1061:methyl-accepting
                     chemotaxis protein (Score: 201; E-value: 5.7e-61)"
                     /gene_kind="other"
                     /locus_tag="ctg3_192"
                     /transl_table=11
                     /translation="MSIRKKILAISIGPVLVLGVITLLFMLTMVKSSLMDEVQDALKGT
                     AAATLAAYDQNTGDYLESTNGDIWKGSYNISKSESLVDRIKENTGMDVTFFYGNKRIMT
                     SALDKKGNRILGSEAGERVVNQVIKGKKPFFSTNVSLDGTRNYGYFIPVYQNGTTDQVI
                     GMVFVGTNKARKDAIVNKILGSIMMALLVVMLLCIVTAMRMAASISKNIKNSVAVVGKL
                     ADGDLNVWVDEKLLKRKDEIGDLSRGTMTLRDAMKSVIRDISENAKQLLSTSQILGTAA
                     DNTNGTMSQVQQAVSLVVDNSSEQAKNSRNTSDHMKIMGENITETTAEVQNLDQNATFM
                     HSSSENASATLEKLCGINEQVEQMLAQVQQQTDRTNDSVQKIQQATTIISSIAEETNLL
                     SLNASIEAARAGESGRGFAVVAGQIKKLAEQSDQSSQEIEQIASTLIRDSSLAVESMQS
                     MQQIITSQSESMAETQNIVKEVLGEINSSMQSIKQIKASTRRLEDSRNEVVQAVGELSG
                     IAEENVESTKKTYDGTQEVVGTFQQVYVSAEQLREISDKLVKGIGYFHI"
     PFAM_domain     14393..14716
                     /aSDomain="sCache_3_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17202.6"
                     /description="Single cache domain 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_192_0085"
                     /evalue="2.50E-24"
                     /label="ctg3_192"
                     /locus_tag="ctg3_192"
                     /protein_end="181"
                     /protein_start="73"
                     /score="85.8"
                     /tool="antismash"
                     /translation="NISKSESLVDRIKENTGMDVTFFYGNKRIMTSALDKKGNRILGSE
                     AGERVVNQVIKGKKPFFSTNVSLDGTRNYGYFIPVYQNGTTDQVIGMVFVGTNKARKDA
                     IVNK"
     PFAM_domain     15248..15724
                     /aSDomain="MCPsignal"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00015.23"
                     /description="Methyl-accepting chemotaxis protein (MCP)
                     signalling domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_192_0086"
                     /evalue="2.10E-33"
                     /label="ctg3_192"
                     /locus_tag="ctg3_192"
                     /protein_end="517"
                     /protein_start="358"
                     /score="115.7"
                     /tool="antismash"
                     /translation="EQVEQMLAQVQQQTDRTNDSVQKIQQATTIISSIAEETNLLSLNA
                     SIEAARAGESGRGFAVVAGQIKKLAEQSDQSSQEIEQIASTLIRDSSLAVESMQSMQQI
                     ITSQSESMAETQNIVKEVLGEINSSMQSIKQIKASTRRLEDSRNEVVQAVGELSG"
     CDS             16018..18432
                     /locus_tag="ctg3_193"
                     /transl_table=11
                     /translation="MNFGYFDDEKREYVITRPDTPAPWANYLGSPEYGALISNNAGGYS
                     FARSGANGRILRYIFNQFDQPGRYIYLRDNESKDYWSASWQPVGKDLESYKSECHHGTA
                     YTKMFADYSGIHSEVCYYVPLNQTYEVWHLKVTNASACERNLTITGYAEFTNNNNYEQD
                     QVNLQYSQFITSTVFETNRIRHIIHGNLDWVKEGEEVDNKLAISRFFALTGAPVDSYCG
                     DKESFLGRYHGYHNPVGVENGKLSGEMCYNENGCGALAAQMLLKPGETKEIAFLVGMKE
                     HEEAEAICNRYADVAAQCETELKELTGYWHEKLEHFQVHTPSREFDTMINTWNAYNCFM
                     TFIWSRAASFFYCGLRNGYGYRDTVQDIQGVIHLAPEMALEKIRFMLSAQVDNGGGLPL
                     VKFTHNAGHEDTPDDASYVQETGHPAYRADDALWLFPTVYKYIAESGNLAFIDEVIPFA
                     NKDEATVYEHLKRALAFSVNHLGPHGLPAGLYADWNDCLRLGKNGESSFVALQFYYAMT
                     ILKQFAAYKEDQAYMDYLEEEQKKLGTLINNLCWNEDRFIRGFTEAGEVIGKRTDPEAN
                     MWLNPQSWAVISGLATKQQAELSMENVRKRLNTEYGAILMDPPYHLHAFDGALAVIYNP
                     GTKENAGIFSQSQGWLILAEALLGHGDQAFTYFMENAPSAQNDRAEIRKLEPYCYGQFT
                     EGKDSPHFGRSHVHWLTGTASTVMVGCVEGILGMRPDFGGLRIAPSIPADWDQFTIEKD
                     FRGKHLHIVVENPEHVQSGCKALYVNEEKMEDNYIPVEKMTDQTKVRLVMA"
     PFAM_domain     16078..16851
                     /aSDomain="Glyco_transf_36"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06165.13"
                     /description="Glycosyltransferase family 36"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_193_0087"
                     /evalue="1.40E-80"
                     /label="ctg3_193"
                     /locus_tag="ctg3_193"
                     /protein_end="278"
                     /protein_start="20"
                     /score="270.4"
                     /tool="antismash"
                     /translation="PAPWANYLGSPEYGALISNNAGGYSFARSGANGRILRYIFNQFDQ
                     PGRYIYLRDNESKDYWSASWQPVGKDLESYKSECHHGTAYTKMFADYSGIHSEVCYYVP
                     LNQTYEVWHLKVTNASACERNLTITGYAEFTNNNNYEQDQVNLQYSQFITSTVFETNRI
                     RHIIHGNLDWVKEGEEVDNKLAISRFFALTGAPVDSYCGDKESFLGRYHGYHNPVGVEN
                     GKLSGEMCYNENGCGALAAQMLLKPGETKEIAFLVG"
     PFAM_domain     16942..18207
                     /aSDomain="Glyco_hydro_36"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17167.6"
                     /description="Glycosyl hydrolase 36 superfamily, catalytic
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg3_193_0088"
                     /evalue="4.20E-146"
                     /label="ctg3_193"
                     /locus_tag="ctg3_193"
                     /protein_end="730"
                     /protein_start="308"
                     /score="487.1"
                     /tool="antismash"
                     /translation="YWHEKLEHFQVHTPSREFDTMINTWNAYNCFMTFIWSRAASFFYC
                     GLRNGYGYRDTVQDIQGVIHLAPEMALEKIRFMLSAQVDNGGGLPLVKFTHNAGHEDTP
                     DDASYVQETGHPAYRADDALWLFPTVYKYIAESGNLAFIDEVIPFANKDEATVYEHLKR
                     ALAFSVNHLGPHGLPAGLYADWNDCLRLGKNGESSFVALQFYYAMTILKQFAAYKEDQA
                     YMDYLEEEQKKLGTLINNLCWNEDRFIRGFTEAGEVIGKRTDPEANMWLNPQSWAVISG
                     LATKQQAELSMENVRKRLNTEYGAILMDPPYHLHAFDGALAVIYNPGTKENAGIFSQSQ
                     GWLILAEALLGHGDQAFTYFMENAPSAQNDRAEIRKLEPYCYGQFTEGKDSPHFGRSHV
                     HWLTGTASTVMVGCVEGILGMRP"
ORIGIN
        1 aaatatgctg atcaaatcga tattagtata gatggtgtag atgaagaaac atgcagtatt
       61 gtcagaggga aaggtgtttt tgaaaatgta ataaggaata ttaaagttct tcaagataaa
      121 ggctttaaca atgtttcatt atcgatggta ttttcagata agaatgaata tttagaacca
      181 gcatttttag aattaaatag acaattagga actactccga ttacacgtgt gtttgctgaa
      241 attggaagag gaaaagattc caaaaatata ttttccgata aaggtattga tgacgtatac
      301 attccagaga cttttttaga tttgaatagc aaacagcaat taggagtaag aacttgttct
      361 gcgggaagaa atcaattatt tgttagatat aatggagaag tttatccttg ccctagttat
      421 atgaaaagag agtattgctt aggaaatatt ttaaaagttc agaaaattga tgaactatta
      481 gttgatagcg aagggaaaaa ggatattcaa gaattaatgc taaaaactga tatgttatat
      541 ggtaaaaaat gtgctaattg tgaactctca ttattttgtt ggacatgtcc tggagaagca
      601 tataatttaa aatctgaggc tgcattagaa aagtattgcg aaacttgtaa accgatgctt
      661 ttacataaaa tatgggggga ataaaatggc agttggatat atgatttggc tgactacagc
      721 ttgtaacttg aaatgtaaat actgctacga gggaacagca aaagttaatt gttatttatc
      781 aaaagattat gcagcaaaga tagtggatta tatagtacag gactgtgata aaacgaaaaa
      841 cttgcaaatt tcttttcatg gcggggaacc ttttttaaac tataaaataa tggaattcat
      901 tagtttagag cttgaaaatc aacttcattc tgttgtaaac gatatttcat atcaagtaac
      961 aactaatgct acaattttaa atgaagaaat tatagaattt ttaaaagacc ataaaattga
     1021 agtgacgtgt agccttgatg gaacaaagga aactcatgac agtatacgag tgtttgaaga
     1081 aaataaagga agttatgata tagcaatgaa aaatagttta aaattgttag cgttatatcc
     1141 agacttaaga gtaagaatga cggttagatc aacagaggta gaaaacttat caaagaatat
     1201 tatatattta gtagaaaaag gatttaatct aattgtacct gtattagatt tttacgacaa
     1261 aaattggaat gaagaaaagt ttgaaattat aaaagaagaa ataaaaaagg ttaaaatata
     1321 tgtaagaaac aaagatgtca ctataagtct tttggaacca ttgagtatta aaaagaagtc
     1381 actgtgccaa ggcggaatac aaactataaa tatctatcct aatggggaca tatatccatg
     1441 tacacttgca gcaggcgata aagaattttt aatcggaaat attgaacaag gaataaatta
     1501 taaaaagtta gaagaaatat tatcttattc tcagaaagaa aataaagaat gtagaggatg
     1561 tgtattttat aatttctgta attccacacg atgcaaaatc ataaataaat tggttacagg
     1621 agattacaat tcgcctaata gcttagaatg caatatgaat catttacttt atgaagagaa
     1681 tggttatttg tgttattaat ttgctggcta atagtttgta atgcaaacaa tattttatcg
     1741 tttgtttaca atataattct aggaaaggag atgaaaacta tgaagatcag aaagatggaa
     1801 aacaaggaat taaaaaaggt tgtaggacag tgttgctgca agattgtagg aaaaccgtca
     1861 gtctatgaaa cagattcctg ctgcctggct gactgtaaaa aagatggccg tgatacagca
     1921 cattatacaa tctatcacta ggaggaaacc aacatgaaaa tcagaaaaat ggaaaataag
     1981 gaactgaaaa aagtaactgg acagtgttgc tgcaagattg taggaaaacc gtcagtctat
     2041 gaaacagatt cctgctgcct ggctgactgt aaaaaagatg gccgtgatac agcacattat
     2101 acaatctatc actaggagga aaccaacatg aaattagaaa aatggaaaat aaagaactga
     2161 aaaaagtaac tggacagtgt tgttgcaaga ttgtaggaaa accgtcagtc tatgaaacag
     2221 attcccgctg cctggctgac tgtaaaaaag atggtcgtga tacagcacat gttacgattt
     2281 accactaagc gggaattaat atgaagatta gaaagatgaa aaacaaggaa ttaaaaaaag
     2341 ttattgggca gtgttgctgc agagtacagg gaaagccggc aatttatgac cctaattctt
     2401 gttgtttgag tgattgcaca cgttttgata aacctgcatc atatgtttca ccactgcatt
     2461 aatcacttct aataaaaaaa aactaaagta aggaaggggc tatcgttata gattcattgt
     2521 ttgagcatga agatataacg atggccttta ttaaaaaaat gagaaaagta acgattgcaa
     2581 taatagattc aggtatagac aaccgtttta agaaccagtt taaatgtaaa gtttcaggaa
     2641 ttggtgtgac attaataaat aatgaaatta aaattgttga ggattatttc gatgaaaatg
     2701 gacatgggac attaacagca tctgttatta tcaacgagtg tcctgatatt gaattcttca
     2761 ttataaaaat attagacaga aaactagagg gaaatatcga atgccttatc gctagcttag
     2821 aatatttatt agataaagat gtaaatatta ttaacatgag tttggcagtt gagaaaaatg
     2881 gaagagatag caggttaaaa aaaatatgta aaaggttaaa tgatcaaggc aaaattttaa
     2941 tagctgctgt tgaaaatggg agcaagaaaa gtattccggc aatttatagt actgttattg
     3001 cagttgaagg aagaaaatta aaacagaatt ttgactttat gttttcttca aataaaagaa
     3061 ttaactgcgt tatacgaagt gagccgcatt tatattatca gaaaaaagat gattatgtta
     3121 tgtatggaga ttgtaatagc tttgctgcag caaaactttc tgggaaacta gcaagaatat
     3181 tacggaagca acctagcaat gacaattcga aagtaaaaaa attattaaga aaagaatcaa
     3241 aattatttgt ttggacggtt ccgcttctta atttgtttaa agaatatcca gtttttagag
     3301 ataataatat tatttatgat ccgataaaat taaataaatt agcaacaaat attgcggtgt
     3361 ttttttctgt agaaaatatt tcagatattt attcgtattc tttgtatagt tcgaaaatta
     3421 gccaaaaaaa agaattcgct tatagattcc ttcgcttttt ggaagaaaag tatggatttg
     3481 tttgtgaaaa ttatagcgtt tttgagagaa atgattttat atctatatat tctgtatata
     3541 aattcttgaa ggagagatac aaatggtaga atttaaagag tatgttatat atatatttaa
     3601 agaaaataaa attaagtcac taatagtttt tgtattaact ttagtcgtaa caacgctaag
     3661 tctactggaa ccacagctat tggtaatttt agtagataaa gctatttcgc acgataattt
     3721 taatttactg tttattgttt ctatatccta tgtaatttta atagttattt cggcattatg
     3781 taagtactct attacagtat tgagaacaaa aattaaaaag caaactacat ataaaatgag
     3841 aacgaaattg ctgttacaca tacaagaatt accgggtaaa tattttacgg aacagaaaac
     3901 aggagatatt ttaaaagtaa tcgatagtga tgtaagtgca ttagaagaga cgggaataga
     3961 ttttgttata gatattatta agaatttatt atctgcaata tcggcttttg tgatattagc
     4021 atgtataaat acgaaacttt tacttattat gattttaatg gagacattta tgttgttttt
     4081 gcatgaaaaa tatataaaac ttgtctctaa aaaattggaa agagttaggg atataagtgg
     4141 aaaatcaatg aatttattag aagaatttgt cgttcatatg atggatataa taattacaca
     4201 tgcaaatata ctcttcttga aaaaatactt aaataatgag cagctttata ttaatgaatc
     4261 cactaagttg gaaaaaatga tagaaaaaaa tcaattaaca gcaaatacgc ttaatgaaat
     4321 tatgtttata gtaatttatt taatcagtgg actttcaatt atacagaata ctatgacaat
     4381 aggaacaatg atggctttta ttcaatatac atcgatgtta atctctccaa tattacaatt
     4441 aaccaattcc aatacaagaa tacatatagc aatcgtatct ctcagaagaa taagaactgt
     4501 tttgcgtatt cccaaaacag ttgatgttgg aacgaaagaa aatatagaag gtaaaattca
     4561 atttgaaaat gtgaattttt catatcaacc tgaagtgaat gtattgaatg attttaatat
     4621 gaaaattgag aaaggtaaaa aaatcgcaat tgttggttgc agtgggtgtg gaaaaagtac
     4681 tttgttaaaa cttttatata gattatggag tccaaatcaa gggaaaatac ttattgatga
     4741 tatacctata gaaaaatatt cattaaaagc tctgagagat agcatagcaa ttgttacaca
     4801 ggatgtgatg atatttaatg atacagtttt aaataatata aatttaacag gggataggaa
     4861 tatttctgaa atcaaaaaaa tgtgtaagaa aatagatcta gaggataatg ccattcttat
     4921 ggatgaaaac ccagagggaa cagttgggga gtatggagtg aaattgtcag gaggacaaaa
     4981 acaaagaata gcaattttgc gtgcaatttt acagaatgca tccatttatg tttttgatga
     5041 agcaacttct gctttagata atctaacaca ggaaaaaata atggaagaga ttgatacata
     5101 cttatgcgga aaaacaacca ttataattgc acataggctt tcgacagtta gaaacgcaga
     5161 ttatatatat gttatagaaa acggtagtgt tgttgaagag ggaacacatg ataagttaat
     5221 gttaaaaaac ggagcgtata agaaaatgta tatgagtgag atatagttat gttttatgtt
     5281 gcgagaggat gttgttgatg actaagaatg tgtcactgcc aaaaaagggt gccagatttt
     5341 ttcactacta gtgggacttc gaaattttca gttttctccg agtatctggt cacggacttt
     5401 cagctctgtt agttccctaa ctcgcatagc agtatcatat ccaagaataa ggagcaactg
     5461 gttccgatgt ttgggatatt tcctttacca actcttcggg atttacgttt ttattgttgt
     5521 ttatatcgcc acctgtagat gtttgtagat ttgtgtggga ggtgtgtgta acaaacttgc
     5581 aaagttcaga tgaaataaaa gttactttaa cacaggaaac aattacatag aaaagattgt
     5641 cataattttt tcgttggcgg taagtttgaa acaaagagat agtggttaga gaaaaagtaa
     5701 atcgcatagc aaacaagcca tctttcggtg gcttttcaaa aaggtaaata tagacacgac
     5761 acctaattca tagccggagt aacatcatcc ttgatagtat atccacgctg ttttagtaga
     5821 ttaagagcct gtgaagtggt cagtattttt gtgattcatt cacaggacgt aattcaagaa
     5881 agccctctgc tgagtatggc ttcaaatcag agagtatgtg ccagataacg gtcaggagca
     5941 tacgacagat tgcaatgatg gctttcttgt gaccacggtg cgattttatg cgcttatagc
     6001 ggtcggttat ttcgggatgt ttcttggaac tcaatggcga atttcagcag gtggaataaa
     6061 ggaaggttta atcatttcac acatgaataa atcacaaatt catttcgcat cctttcggtc
     6121 agtcttgttt cctttttgta gtttcgtata tttgggatga gcaagaataa cagaaatatt
     6181 tgctttttcc aaaatattaa atacagggat ccaatacttg ctggtagatt ccatacaaac
     6241 ttcagaacaa ttgtattttg caagctaatc acacagttcc ttcaaacctt tggaaaaaga
     6301 agagaaacga gcttgcttgt aatcagttct gccctttgaa tcagtgatac cgatgcaagc
     6361 ataaatccat gttttgtgga catcaagccc acagcaatta aaacgaaaaa ttttgaaagc
     6421 caataaaata acctcctgat tttgtagtaa taaaactgac aatgactggt catctggcaa
     6481 aatcgagtcg actttggaag agataagttt acgggctacg ttatgcacca ttcattgatg
     6541 ccttaacgga tgaccgatga catatatatg tgaacttcca ctgatttgta caactaaata
     6601 tataaatacc ccataatttt aagctttttg gggaatatgg tgtaatttta ttaatgcgta
     6661 tttacgacta ctggttcacc tatatttcca cagaaaatcc agtatttatg cgggcaaatc
     6721 gattttagtc gtaaatttat tggaagttca cagtttcata accccatcag tgcctttcgc
     6781 aggggaaagg cggaatatat atggataatg gagccagtgg ataaaataca gtaattgatt
     6841 acttctatta tttgtatcat aagaaccttt ttaaggtagc atatatctat aatatgttta
     6901 agaggtaacc aattatggag agtcgtatca aacaacttcg tgaaaataga gggctgatac
     6961 aggaaatttt ggcttctgaa ttaggaatta cacaacaaat gcttagtaaa tatgaaagag
     7021 atgtgttgtg tattaaagtg gatgtgttaa agaggatagc cgaatatttt aatgcgacaa
     7081 cggattattt actgggagtt tcagaagtga agagagattt gcaaggacag atgaaagtga
     7141 acaagacatt agacacctat tatgatctta tcgagatata taaaggttta gatgagtatg
     7201 atcaggaaat ggtatggtca attatgcaaa cggtaaaaaa agctggtgaa aaacgtaaaa
     7261 gagacaggga aaatacagaa gagagttgat aagaaatgct gaatatagca atttgtgatg
     7321 atgatattca gacaaccgga agaatggata tgctgttgca gaaaatagca aagcgaaatt
     7381 ttatggatgt tgaaattgaa gtgttttgga atggaaagag tcttgcagat gcagttgcaa
     7441 aggggactta ttttgacatg atttatttgg atatagaaat ggacaaagaa gatgggattt
     7501 cggcagctaa aagaattaga gcctatgata aaaacgttct tattatttat gttacaagcc
     7561 acgaaaatca tatgcaggag tcttttgaag tcagaccgtt tcgtttcctt gtgaagccag
     7621 tgagtgaaaa acagattgaa tcgtgtttta aatcagcata cgaagaagtg tattgcggag
     7681 attcgtattt tcggtatagc tatcagaggg taaaccataa aataccaatt cgtgaaattt
     7741 tgtactttga gagcaataaa cgtaaagtat ttattgtgac ggaaaaagat acatttgtcg
     7801 catatggaaa attaaatgat atagaggaaa gtcttaaaca aagcaaagtg ccatttttac
     7861 gtgttcatca gtcatatctt gtaaattata agcatgtgga agggcaggca tatgatttcg
     7921 tagttatgga taatggcaaa agaatttcaa tcagtgaaga cagaagaaaa ttaatcggag
     7981 agcagtactg ctcaatggag gacacatttt atgtcaatga gtaagacatt gtcatatgga
     8041 gttgatatat tgtttatcat atttgcagca tacctgttct tttgttattt cgatatattt
     8101 ttaaaaagaa gaaaaagaac agttttgtca gtggttggat tggtagcatt tatggcatgg
     8161 caatttgaaa tgtcgagcgt taatttgcta ccagcttatg gcaatattat tattacgagt
     8221 atcactacat tgtttgcggt tgctcaaact tatgagggaa aattttggaa caaatgtatt
     8281 tttacaattg cttttaatgc aatctggatg ttaatggaaa cattaagcaa ttatatgctt
     8341 atgacctatt gcgaacaata tgcagaatct gaagcattgg gttcggttac ttcaaaattg
     8401 attttcttga taataattgt ggcattgaaa aaagtgttta ctgatgatga aatcaaggaa
     8461 ttacctgtaa gatatagtat tatgtttgtt ttgattccaa cgggaagtat ttacattatg
     8521 aacaatattt ttatgcttgg atataaagtt catagcaacc gggcaagttt ccattctgca
     8581 attacggcgg ttattctttt gttcatgaac atattgatat tttatattta tatgaaattg
     8641 gcagatgatc tgcagctaag aagaataacc tctgtttatg aacaacaatt agatttgtgt
     8701 gaacggcatc agcaagagag agaactgtca atacttcaat taagagatgt aagacataat
     8761 atgaaaaaca atcttgtgtc gattcttgca tatgcggaaa acggagataa tgaaaaaatc
     8821 atcggatttg tcaatgaaat aatggaagaa ggtggaataa agacatctgc agttacaaac
     8881 agtggaaata ttgttataga ttcactgatt ggatattggt atgttgcagc aaagaaagct
     8941 ggtatagagt tttccgtcaa tttaaatatt cctatggaaa tgccgtttag aggagcggat
     9001 atttgcctaa tacttggcaa tttattagaa aatgctgtag aagcaacaca aagagcagag
     9061 ggtgaaaagt acattagact tcacatgaaa tatgataaaa ataatctgct gttatttgtg
     9121 gaaaataatt acaaaggtgt gcttataaag acgaaagata aaaggttaaa gtctacaaaa
     9181 acagatgctg gaaatcatgg tgtaggtatt ccgtctgtat atcgaattgc tgcaaaatat
     9241 catggagtgg ttacgattga tgataatgtg gcaaatcgtt ttttgatcag agtagtgtta
     9301 tacggaaagc agaaataatt acattaatag tcggtattat tacattatgc ttagcattat
     9361 gggaaaaaga gataaaataa aaagataatt ttagggaaat ggtgaatgct ttttagaatg
     9421 gtattgtggt ggtgcagtat gatggaagtg ttattattca gtaatgatga aaagattttt
     9481 aatttgacaa atagtgtaat agatggaaga tataaattaa catggtgtac ttataagtct
     9541 ttagaaaaaa aaacatgtcc atatccatat ccagatatag ttattatgca ctttgataaa
     9601 gagatggtta agaaagggac atttaaaaca attgttcagg taaaggggag actagggcaa
     9661 aggataccaa tccttgcgct gatggaagaa ggaacaccgc aaaatatttt ttcaacatta
     9721 atagcgggtg cctatgatta tttagaaatt gtgaaaaatt caaaagaata taaaaagaaa
     9781 atagaggatg ctatccggtg gaattggtat ctgggaaagt atggactgag agaaaaatag
     9841 tagtgatatt gaacgtcact actatttttg cgttacatga aaaaaggaga aagagcagtt
     9901 tcagaaaaag ttacatgaat actcgttttt tttacaagaa agatatattg gctgattttt
     9961 gtagtagtgt aaaggaaaca aatgaaagga gattcaaatc atgaattcta aaaaagtaaa
    10021 aaatcagtca gcaaaagtat tggcaaacgt atctctgaaa ctcggcaaaa tgtcagcaga
    10081 tagtgcgtgc tgctatattt atcatcagcc taaaatgccg gaagccctga aaaaaatgaa
    10141 aaatatttaa tatgaaatat ttttcggaga aactgacagg ttatattgtt aaatctggtg
    10201 ctgttccaga ggaatcatat gaaatatacc aatatgggtt tcaaatagga cttgaaatgt
    10261 tgagctgtct tttagcttgt tttggaattg cggtatattt gcatatgatt ccggaatttg
    10321 cagtggttac aggaattttt atgatgttac gcagttttgt tggcggagtg catctaaaca
    10381 gctttagtgc ctgctttatg tgttctgtta ctgtgcagac gttggtattg gttgttaatc
    10441 gtctgtatac acaaccatta aatgctgcgt ggggaataat tgtgttgagc agtattctga
    10501 tatggaatat ggctccggta caaagcatta accgggaact tgatgcagat gaaaaaagac
    10561 actgcagaaa ggtagctgta aaaattattg cgggcatata tgtgtttgcg gggatttgta
    10621 cacttactgg gatgaaagca atagtgtctt tggttgcagt gacaatggca gtagttttga
    10681 tttcacaata tattggggta gtaaagtata aaatagaaaa gagataataa gcgggaatag
    10741 tagaaatcta ttatttccgc ttattttatt tgaggacaaa agaattgttt attttttcta
    10801 ggtaacactg ttttggtaat aaaaaatgtc tgttaggctt cggctcagga ggcgcttctt
    10861 gttataagga taaaaaaatt cttccagacc cgaagatggg ggactttcta tacgagatat
    10921 gggtgaaagg gaaaaaacct ttactcatat cttgtggacg ggaaggcggt gaactctatg
    10981 gagcaatctt ctttctatga tgaaacaacg gtcagacatc agtttgatag gaaatgcaaa
    11041 ctggcactgg atgacgaagt ggtagattat gacaggcata tggattaccg gagaaagaat
    11101 gaagtactgt tttcgaaatt atctgaatgc caggcaggag aattttcggt gttggatgaa
    11161 tataatctgg aaatatattg acttcaagta atgagttagg acattgaagt aaaagatggg
    11221 ttgattgttg agactctgcg aattctcata aaaagaagcg aaatgtaatt tttctgttgt
    11281 attttccagg cacacaaagg agcagtacat attttaaaga aaaatacaaa agaaaagagt
    11341 ctaacttaag aaagagcgtt tggtggtgtc acaattctag ataggattgc ggcacttttc
    11401 ttttcgacaa aattcgaagc aggtttacag aataaagcca gagcgccacc acattccgat
    11461 ttgatttcaa aaattcagat cggaggttaa gaaaagatga cttttaataa agcaaaggcg
    11521 gagaaacaat ggctgaaatg gaaagaaaca gaagaggaaa agcttcggca actcggaatg
    11581 gacgaagaat caataagaaa acttcggcag atggattggg aagatttcaa ggaggaacgc
    11641 agatactggg aacatttcgt agaaagcaga ggagaagcaa ctggggagaa aagaagtttc
    11701 cttattaaaa cgcttataga aggaaaggaa tgcggaaatg aaatacgata aaatagttgc
    11761 catgaatcaa gaaaagagta ggaaaaaagt ggacgtgcta aaagagaaat gaagaagata
    11821 aaggagtatg cagaacgagg atacactcat gcggtggcac ttgatttgtc gaaatacttt
    11881 gatacactca accacgaaaa gctcctaaat ctgttacgta gagatataaa agatgaaaga
    11941 gtgatacagt ggattaagag atatctgaaa agtggtgtta tggagaacgg agtagtcatg
    12001 gaaacagaag aaggttcgcc acagggtgga aatatctcgc cattgttagc gaacatctat
    12061 ctgaatgagt tcgaccaaga gtatgagaaa cgcggagtta aatttgtcag atatgcagat
    12121 gatatcgttc ttcttgcaaa gagtgacaga gccgcaaaac gattacttga aacaagcacg
    12181 aaatatcttg aaggaacact gaaattaaag gtgaaccaag agaaaagtcg agtggtcagt
    12241 gtgtttgcaa tccgaaattt taagtacctt ggcttcacat tgggaaagaa cggaaagggt
    12301 atctatatcc gcgttcatgg gaagtcatgg aagaaaatga agtcaaagct gaaagaactt
    12361 agttcccgaa ggtcttgcca gagtatacgc ccatcactac aagagataaa agagtatatg
    12421 cgagggtggc tgaattatta tggggttgca gatatgaaga agaaaataga tgatttaaat
    12481 aaatggctat atcacagaat ccgtatgtgc atctggaaac aatggaagaa accgaagaca
    12541 aagataagaa atctgctaaa gatgggagta ccaaaggact tggcatggca agcaggaaac
    12601 agtcgcagag gatattggtt tgtgactcat acgatagcgg tcaatttagc aatgacaaaa
    12661 gaaagactga taaacagtgg cttttatgat ttagccaccg cctatcagtc tgtgcacgtc
    12721 aactattgaa agcgccgtgt accgaacgat acgcacggtg ctgtgagagg acgggagtta
    12781 gtcactccct cctactcgat taaattacgg cattgtcgtc taatcattct tcaatggaac
    12841 caaatactat ctttgtaaca gaaacgctct tgggtgctga catatttttt actggaaaat
    12901 aagaggaaaa ttagctataa tcgtagtaag agctagggga gaagaaacaa caggaatata
    12961 taatgtgcga aggaggaacg ctatgaaatg gaaagggcga agactgcttg ccatggcact
    13021 taccggtatc ttgctggcag gatgcggggc agccggacag gtcgatgatt atgcaacaaa
    13081 tgagggaagt acacaggagg cttccaccaa aacaacggga actgaaagcg gagggatttc
    13141 aaaggacaag atcagggtag gggttttgca cttatcggat ccggcagaag gcagtggata
    13201 tacctataca catgatcttg gcattcaggc aatgcagcag aatcttggat tatcagatga
    13261 acagattgac agaaaaataa atgttgatga ttcggataaa gaggcaaccg aaaaagcgat
    13321 tcaggagtgt gtggatgacg gatgcaatat tatttttacc accagctggg gatatatgga
    13381 tgccacggag gagatggcgg aaaaatatcc ggatatatat tttgcacatg gaaccggata
    13441 taagagcaac ggcaaaaatt tcgtaaacta tttcggacga atctatcagg caagatattt
    13501 aagcggaatt gtagcgggaa tgaataccaa aaccgataaa ctgggatatg tggcagcaat
    13561 ggattcctcc aattccgaag tgacaggcgg tatcgatgcg tttgccctgg gtgtctattc
    13621 ggtgaacccg gatgcaaaga tttatgtgaa agtgacgaac agctggtttg acccggatgc
    13681 ggagaaagca gcagcacaaa ccctgttaaa tatggactgt gatgtggtca cgcagcactg
    13741 tgatacagaa tatccacaga caatggcaca ggaaaaaggg gtgtatggta tcgggtacaa
    13801 ttccgatatg agcaaaaatg ctccggatgc ctgtctgtgc agcgtgatct ggaactgggg
    13861 tgcttattat acagcagcgg tgcagagcgt gattgacggt acctgggatg gaagcaatta
    13921 ttatggcggt atgaatgaaa atctggtagg gattacgtca cttgctgatt tttgcacaga
    13981 tggaacacag gaggctgtgg atactgcaaa agaagatatt ttatccggga aaaacggtgt
    14041 gtttgacggt gtgattgaaa caaataccgg ggaaacggtt ggtgaagaag gaaaaacgct
    14101 ggatgatgcc acaattacag gtggaatcaa ctggtatttt aaaaccgttg aagtggtaga
    14161 atagggggca tatatgagta tacgaaagaa aattcttgca atcagcatag ggccggtgct
    14221 tgtattaggg gtaattaccc tgctttttat gcttacgatg gttaaaagct ccctgatgga
    14281 tgaggtacag gatgcattaa aaggtaccgc ggcagccacc cttgccgcct atgaccagaa
    14341 taccggggat tatctggaaa gtaccaatgg ggatatctgg aaaggaagct ataatatatc
    14401 aaagtcggag agtcttgtgg accggatcaa agagaatacc ggtatggatg taaccttttt
    14461 ttatggaaac aaaaggatta tgacatctgc actggataaa aaaggaaacc gtatccttgg
    14521 ttcagaagcc ggagagcgtg tggtgaatca ggtgatcaaa gggaaaaagc cgtttttcag
    14581 tacaaatgtt tcactggatg ggacgagaaa ttatggatat tttattccag tgtatcagaa
    14641 tggaacgaca gatcaggtta tcggtatggt gtttgtcgga accaataagg cacgaaaaga
    14701 tgcaattgtc aataaaatcc ttggaagtat tatgatggca ttgcttgtag tgatgctttt
    14761 gtgcattgtt acggcgatgc gcatggcagc ctctatcagt aaaaatatca aaaacagtgt
    14821 tgctgttgta ggaaaacttg cagatggtga tttaaatgtg tgggtagatg aaaaacttct
    14881 gaaacgaaag gatgagattg gtgatctgtc tcgcggaacc atgacattaa gggatgccat
    14941 gaagtccgta atccgggata tttcagaaaa tgcaaagcag ctgctttcaa cgtcacagat
    15001 tctgggtacg gcagcagaca acaccaatgg aacaatgtca caggtacagc aggcggtcag
    15061 ccttgtagtg gataattcca gtgagcaggc gaaaaattcg agaaatactt cggatcatat
    15121 gaaaattatg ggggagaata tcacggaaac tacagcagag gtacaaaatc tggatcaaaa
    15181 tgccacattt atgcattctt ccagcgaaaa tgcttccgca acgctggaaa aactctgtgg
    15241 gatcaatgaa caggtggagc agatgctggc acaggttcag cagcagaccg accggacaaa
    15301 cgattctgta cagaagatcc agcaagccac aaccatcatt tcttctattg cagaggaaac
    15361 caatctgctg agcctgaatg cctccattga agctgcccgg gcgggagaaa gcggccgcgg
    15421 attcgctgtg gtggcaggtc agattaaaaa acttgcagag caatcggatc agtcgagtca
    15481 ggaaattgag cagatagcgt caacgctgat cagggattct tcccttgctg tggaaagtat
    15541 gcagagtatg cagcagatta ttaccagcca gagtgagagc atggcagaaa cgcagaatat
    15601 tgtaaaagaa gtgctgggcg aaattaacag ttccatgcag agcatcaaac agatcaaagc
    15661 aagtaccaga cgtctggaag attccagaaa tgaagtcgtt caggcagttg gggaattgtc
    15721 cggaattgcg gaagaaaatg tggaaagcac gaaaaaaacc tacgatggaa cacaggaagt
    15781 tgtgggaacg ttccagcagg tatatgtaag tgccgagcag ttgcgtgaga tttctgataa
    15841 actggtaaaa ggaatcgggt attttcatat ttaaaagaaa cacagagtgt cggaaaattc
    15901 cggcactctt tttatgtcat gaatctggta taaatcctgt gattctgata ttcataaatt
    15961 tatgaatccg ttacaatagg gtaaaaggct tgcaaattga aaggttggag gtttcacatg
    16021 aattttggat attttgatga tgagaaaaga gagtatgtaa tcacacgccc ggatacaccg
    16081 gcgccgtggg cgaattatct ggggtcaccg gagtatggtg cgctgatttc aaataatgca
    16141 ggaggataca gttttgccag atctggtgca aacggaagaa tcctgcgtta tatttttaac
    16201 cagtttgatc agccaggacg ctatatttat ctgcgggata atgagagcaa agactactgg
    16261 tctgcatcct ggcagccggt aggaaaagat ctggaaagtt ataaaagtga gtgtcatcat
    16321 ggaacagcat acacaaagat gtttgcagat tacagtggaa tccattctga agtatgttat
    16381 tatgtgccgt tgaatcagac atatgaggtc tggcatctga aagtgaccaa tgcgtcagcg
    16441 tgtgaaagaa acctgaccat caccggttat gcggaattta ccaacaacaa taattatgaa
    16501 caggatcagg taaatctgca gtattcccag ttcatcacga gtacggtatt tgagacaaac
    16561 cgtatccggc atattattca cggtaatctg gactgggtga aagaaggaga ggaagtggat
    16621 aacaagcttg caatctcccg tttctttgca ctgaccggtg caccggtgga cagttactgt
    16681 ggagataaag aatcgtttct tggacgctat cacggatatc ataatccggt gggggtggaa
    16741 aacggaaaat tatccgggga aatgtgctac aacgaaaacg ggtgcggagc actggcagct
    16801 cagatgcttc tgaaaccggg agaaacaaag gaaattgcat ttcttgtcgg aatgaaagaa
    16861 catgaggaag cagaagcaat ctgtaaccgc tatgcagatg tggcagcaca gtgtgagacg
    16921 gaactgaaag aactgacggg ctactggcat gaaaaactgg aacattttca ggtacataca
    16981 ccaagcaggg aatttgatac catgatcaat acctggaacg catacaattg ttttatgaca
    17041 ttcatctggt cacgtgcggc gtcgtttttc tactgtggtc tgcgaaacgg ttacggatac
    17101 cgcgataccg tgcaggatat tcagggtgtg attcatcttg caccggagat ggcactcgaa
    17161 aagatccggt ttatgctttc ggcacaggtg gataacggag gaggacttcc acttgtcaaa
    17221 tttacacaca atgccggaca tgaggatacg ccggatgatg cttcctatgt acaggaaacc
    17281 gggcatccgg catatcgtgc ggatgatgct ctgtggctgt ttccaacggt atataaatat
    17341 attgcggagt ccggaaatct ggcatttatc gatgaagtga ttccgtttgc caataaagat
    17401 gaagccactg tatacgagca cttgaagaga gcacttgcgt tttctgtgaa tcatctggga
    17461 ccgcacggac ttccggcagg actttatgcg gactggaatg actgtctgcg tctgggcaaa
    17521 aatggagagt cctcgtttgt tgcactgcag ttttattatg caatgacgat tttaaaacag
    17581 tttgccgcat acaaagaaga tcaggcatat atggattatc tggaagaaga acagaaaaaa
    17641 cttggaacat taattaacaa tctctgctgg aatgaggatc gttttatccg tggatttacg
    17701 gaagccggag aggtgattgg aaaacgcacg gatccggaag caaatatgtg gctgaatcca
    17761 cagagctggg ctgtgatcag tggactggca acaaagcagc aggcagaact ttccatggaa
    17821 aatgtaagaa agcggttaaa cacagagtat ggagcgattc tgatggaccc accatatcat
    17881 ctgcatgcat ttgacggagc actggctgtg atttacaatc ccggtacaaa agaaaatgcc
    17941 ggtatctttt cccagtcgca gggatggctg attctggcag aagcattgct ggggcatggg
    18001 gatcaggcat ttacctattt tatggaaaat gcaccgtctg cacagaacga tcgtgctgag
    18061 atccggaaac tggagccata ctgttatgga cagtttacgg aaggaaaaga cagcccgcat
    18121 tttggtcgtt cccatgtgca ctggctgacc ggaactgctt ccactgtaat ggtaggatgt
    18181 gtggaaggaa tccttggcat gcgtccggac tttggaggac ttcgtattgc accatccatt
    18241 ccggcggact gggatcagtt taccattgag aaggatttcc ggggaaaaca tcttcatatt
    18301 gtggtagaaa atccagagca tgtacagagt ggatgcaaag cgttgtacgt gaatgaggaa
    18361 aagatggaag acaactacat tccggtagaa aaaatgaccg atcagacgaa ggtacgcctt
    18421 gtgatggcat agaagggaga agttatgaaa aacgatatgc agtttacagg aaaaaacgga
    18481 gaatttcaaa tccgtcatat ggttgaaaaa acacagctca attttccggt ggcaaatgaa
    18541 gaaggaatca aaagcagcgt gacgcagacc ttcggcggcg attgtaagct ggatcagaac
    18601 cattttctgc tggaaccggt gagcatcgaa aatctgcaca ataacagaag tacccgcaat
    18661 gtctggtgta caatcaaccg gaaggaacat gtgtcactga ccggagtttc ggcgcaggca
    18721 gaatatgcac atttccttgg aaaagaggag gaagtgacat tcgatgccgg atttatgtgg
    18781 caggagacga agcgggaatt aaaagaacag aaaatcgagg cagccgtgcg gatctttgct
    18841 ccgcttggag taccggcaga actgatgcag gtgcgcgtta ccaataaatc ggatatggat
    18901 atgtgtgtgc gcgtgacttc tgctatccca atttacggca gaagcgcgga taatctgcgc
    18961 gatcaccgcc atgtaacttc cctgcttcac cggatccgta ctaccggacg cggcgtgatc
    19021 tgtaaaccgg tattgtcatt tgatgaacgc ggacatcaga aaaatcatat gatttatttt
    19081 gagatgggca gtcagggaga tggaacaaaa ccggaatcgt tcttcccaac ggtggaatcg
    19141 tttatcggag aaaccggaac atttctggca ccggatgcgc ttaaaaataa agaaaaaggc
    19201 tgtccggccg gttgtaccgt ggatggaaaa gaagcaatgg gggcgatggt atttccggag
    19261 attacccttg cagcaggagc acatgtcgat tatattctgc ttggtggcat gacagaggat
    19321 ctgaagctgg cagaacaggc agcagaaatg ttttgcacga ccgaacaggc agatgctgcc
    19381 tttgaacagg caaaaaatta ctggaatggg ctggtcaata tttcctttga aaccggaaac
    19441 cccaaagaag acagttatct gaaatggatc tgtttccagc cggttcttcg cagaatctac
    19501 ggatgttcgt ttttgccgta ccatgattat ggcagaggcg gcaggggctg gcgtgatctg
    19561 tggcaggatt gtctctccct tctgattctc gacccgaagg aagttcgctc catgatttta
    19621 aacagctttg cgggtgtccg ttttgacggg accaatgcga caattatcgg ggataagccg
    19681 ggagaatttg ttgcagaccg caacaatatt acaagagtct ggatggatca tgcgtactgg
    19741 ccgtttgtta ccacaaaatt gtatctgaac cagacgggag atctggatat tctggatcag
    19801 aaagtggcgt attttaagga cccacaggca aagcgtggaa ctgccaggga cgcagagtgg
    19861 acaccggcat atgggatgcg ccagaaagat gtaaatggca atatttacga gggcacggtt
    19921 ttagaacatc tgcttttgca gaatctgtgc gctttctacg aggcgggaga acatggaatg
    19981 atgcgtcttc gcggtgctga ctggaatgat gcactggata tggcagcgga aaaaggagaa
    20041 agcgtggctt ttacctgtgc gtatatcgga aatctccgtg atttggcaga tacccttgaa
    20101 aaatacgaag cggcaagcgg aaagaaagag attacactgg caaaagagat ggaaattctg
    20161 atcagacagg accgcacatc gtatgattcg gcagaaaaac ggaatgttgt tttaaacaat
    20221 tatgtgagtc agtgtgtgca taatatttct ggagaacaga tttctgtgga tatcagtact
    20281 ctggtgcaga atctgcggga gcgtgctgac tggtataccg gattgatccg tacgcaggaa
    20341 tgggtaacgg atgaaaacgg aaatggctgg tttaacggat attatgataa tcacggcaga
    20401 ccggtggaag gcaaaaggga taatcatgtc cgtatgatgc tgaccggtca ggtattttct
    20461 gttatgggaa atgtcgcaga tgatgcacag accgctgcga ttataaaaag tgcagacctg
    20521 tatctgtata aaaaagaggt gggaggctac cggctgaaca cggattttaa ggaagaaaaa
    20581 tttgatctgg gacgaatgtt tggatttgct tatggcgaaa aagaaaatgg tgcggttttt
    20641 tcccatatga cggtgatgta tgcaaatgca ttgtatcaga gaggttttgt aaaggaagga
    20701 tacaaggcat tgtatactct gctcgaa
//
