LOCUS       NZ_HG916826.1          10837 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HG916826.1 Pseudomonas oleovorans CECT 5344 strain CECT5344
            chromosome I, complete sequence.
ACCESSION   NZ_HG916826
VERSION     NZ_HG916826.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:57:32
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2204951
            Orig. end    :: 2215788
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10837
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2209951:2210788](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5837)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10837
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10837
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             380..2107
                     /locus_tag="ctg1_2043"
                     /transl_table=11
                     /translation="VARIRRLIISNFRSIQALDWVPAPGINCLIDPGDSGKSSILDAID
                     LCVGARRGGTFGDMDFFALNVDVPITISVALGDLPLSLMDIDVYGEFLRGFHPGTGEVE
                     DEPRAGLETVITLRLQVGADLEPVWTLFSERAEQQQLERTLPWKERAALAPARIGSFAS
                     SNLSWSRGSVLNRLTDERAELGAELARAARQARANFGNQAAEHLTQTLEVVQRTAQHLG
                     VSVGAMPQALLDAHSVSIGEGAIALHSDTGIPLRSLGTGSSRLLVAGLQRAAASAAPIA
                     LVDEVEYGLEPHRLMRFLDSLGAKDAAAPLQVFMTTHSPVALRELSGSQLFVVRSAPQR
                     HSVMPAGEANEVQSTLRKDPEAFLAKSIIVCEGASEVGFARGLDQWWVSLGATSFLAHG
                     GAYVDAGGGSPDNSLIRGTALLNLGYRVMVFVDADKPSTAGLAEAFLAAGGQILTWRPG
                     LTLEDEIFRHLSEQALDALLAKAETIVGAELMNAHIQTKSQGRVTLNDIRAKRLVDGYS
                     PERRELLGTASRIRNSGWFKSLTTYQEVARDIVGPSLQNAELGFMAVTNQLWTFTSAP"
     PFAM_domain     1124..1348
                     /aSDomain="AAA_21"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13304.8"
                     /description="AAA domain, putative AbiEii toxin, Type IV TA
                     system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2043_0028"
                     /evalue="9.20E-12"
                     /label="ctg1_2043"
                     /locus_tag="ctg1_2043"
                     /protein_end="323"
                     /protein_start="248"
                     /score="45.4"
                     /tool="antismash"
                     /translation="SDTGIPLRSLGTGSSRLLVAGLQRAAASAAPIALVDEVEYGLEPH
                     RLMRFLDSLGAKDAAAPLQVFMTTHSPVAL"
     CDS             2427..3524
                     /locus_tag="ctg1_2044"
                     /transl_table=11
                     /translation="MQLLQAGHLAQPLRATYARLLVDEYQDCNVVQHAIVSGLAQVLPT
                     CVLGDPMQAIFSFRGNRLVHWANEVQPLFPAAGELRIPWRWRLAGAENLGQWLLAIRQQ
                     LQAGQPVDLRTAPAEVRWVQLNAGTEVQQRLVAARTEAPNAQGSVLIIGDSINVQGRHQ
                     LTSQTPGAMAVEAVDLRDLVNFARNFDLQGANALAQLVEFASSVMTGVGAANLRTRVES
                     LRAGRARTPPTAAEAAAIDFVAAPTLGQALRVIDTLAEQHGARVYRPEVLYCCRSAMQA
                     VVGGAADFLSAAIQARERNRHLARPIARRSVGSTLLLKGLEADVSVVLHPELMTPQNLY
                     VALTRGARHVVVCSPTPILTPVVNG"
     PFAM_domain     2433..2609
                     /aSDomain="UvrD-helicase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00580.23"
                     /description="UvrD/REP helicase N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2044_0029"
                     /evalue="2.30E-11"
                     /label="ctg1_2044"
                     /locus_tag="ctg1_2044"
                     /protein_end="61"
                     /protein_start="2"
                     /score="43.9"
                     /tool="antismash"
                     /translation="LLQAGHLAQPLRATYARLLVDEYQDCNVVQHAIVSGLAQVLPTCV
                     LGDPMQAIFSFRGN"
     CDS             3622..3822
                     /locus_tag="ctg1_2045"
                     /transl_table=11
                     /translation="MFSLSVAGMGCGSCVSKITKAIQALDQDARVEVDRAAGKVTVEST
                     ESAESIRELIQELGYSAQVSA"
     PFAM_domain     3631..3801
                     /aSDomain="HMA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00403.28"
                     /description="Heavy-metal-associated domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2045_0030"
                     /evalue="3.80E-15"
                     /label="ctg1_2045"
                     /locus_tag="ctg1_2045"
                     /protein_end="60"
                     /protein_start="3"
                     /score="56.2"
                     /tool="antismash"
                     /translation="LSVAGMGCGSCVSKITKAIQALDQDARVEVDRAAGKVTVESTESA
                     ESIRELIQELGY"
     CDS             complement(3842..4159)
                     /locus_tag="ctg1_2046"
                     /transl_table=11
                     /translation="MTHRIIHFKQQALLDPETYQAMLADGVGHWERLAGEVVGIEDEKS
                     HEFAALKSLFKRKRYPYDDTLEMREPGDHSNWLRGRDGSEGMTNEVTSIPGLKELSELE
                     I"
     CDS             complement(4210..5004)
                     /locus_tag="ctg1_2047"
                     /transl_table=11
                     /translation="LSLIALQTAFETYLTGDSALPSNELLEQIRGSTALSALEGLQIYH
                     NAYRSRLLAVLREDFPALLHWIGNESFEQLALAYLAAWPPRHFSIRWLGEKLPEFISSY
                     VEEPQLSPMRELAELEWAFTLAFDAQDVEALSLETMSDFSAEDWISLRVSLTASARWLQ
                     LQYNTLELWKAAKSGSLLPDITRLPTNLACLVWRHELVCQYRSLEPAEASALQFLIEGG
                     SFAELCESLSATHGEQAPLQAATWLKLWVNDGLLKRGQLLHE"
     PFAM_domain     complement(4702..4989)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2047_0031"
                     /evalue="7.80E-21"
                     /label="ctg1_2047"
                     /locus_tag="ctg1_2047"
                     /protein_end="101"
                     /protein_start="5"
                     /score="74.2"
                     /tool="antismash"
                     /translation="LQTAFETYLTGDSALPSNELLEQIRGSTALSALEGLQIYHNAYRS
                     RLLAVLREDFPALLHWIGNESFEQLALAYLAAWPPRHFSIRWLGEKLPEFI"
     CDS             complement(5001..5837)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2048"
                     /sec_met_domain="DUF692 (E-value: 9e-101, bitscore: 334.6,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKRKTLGFGLGLRNEYYRQILEERPAVDWFEIISENYLVEGGKA
                     LYFLDAIGEHYPLVMHGVSLSIGGSHALDIDYLRQLKQLADRVQPQWVSDHLCWSRGNA
                     HQLHDLLPLPFTQESLLHVAARVRLVQDVLERPIVLENVSSYVQWTTSSMSESQFLSEL
                     SYLTGCELLLDVNNVYVSSRNQGFDPWQFIMELPHERIRQIHLAGHSDYGQYLIDTHDQ
                     PIADPVWSLYSKTLSYLGPTSTLIERDDQFPPLEELLSELAHARAIAKSVISGATP"
     PFAM_domain     complement(5031..5816)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2048_0032"
                     /evalue="1.10E-109"
                     /label="ctg1_2048"
                     /locus_tag="ctg1_2048"
                     /protein_end="269"
                     /protein_start="7"
                     /score="365.9"
                     /tool="antismash"
                     /translation="GFGLGLRNEYYRQILEERPAVDWFEIISENYLVEGGKALYFLDAI
                     GEHYPLVMHGVSLSIGGSHALDIDYLRQLKQLADRVQPQWVSDHLCWSRGNAHQLHDLL
                     PLPFTQESLLHVAARVRLVQDVLERPIVLENVSSYVQWTTSSMSESQFLSELSYLTGCE
                     LLLDVNNVYVSSRNQGFDPWQFIMELPHERIRQIHLAGHSDYGQYLIDTHDQPIADPVW
                     SLYSKTLSYLGPTSTLIERDDQFPPLEELLSELAHARAIA"
     CDS             complement(5883..6143)
                     /locus_tag="ctg1_2049"
                     /transl_table=11
                     /translation="MSNKSNVATGAALALVAASLFSTLPVQAAQETKAAEVKCFGINGC
                     KGQNDCMTAKNDCKGQGECKGQGFKLMTQTKCDEAGGKTSE"
     CDS             6427..6633
                     /locus_tag="ctg1_2050"
                     /transl_table=11
                     /translation="MKSIKTLFVVAALSVSSLAMAEGGADRTFARMEQARQTSLEAYRV
                     AQQQKVEAPVASSPTEQAEHTNC"
     CDS             6828..8642
                     /locus_tag="ctg1_2051"
                     /transl_table=11
                     /translation="MQSKTTRRTFVKGLAATGIIGGLGLWRTPVWAVNSPGQPNVLTGN
                     EFDLFIGETPVNITGAARTAMTINGSLPGPILRWREGDTVTLRVRNRLKEDTSIHWHGI
                     ILPANMDGVPGLSFHGIAPDGMYEYKFKVNQNGTYWYHSHSGLQEQLGVYGALVIDAKE
                     PEPFSYDRDYVVLLSDWTDENPTRVLAKLKKQSDYYNQHKRTVGDFIDDVSEMGWSAAV
                     ADRKMWAEMKMSPTDLADVSGYTYTYLMNGQAPDGNWTGIFKPGEKIRLRFINASAMTY
                     FDVRIPGLKMTVVAADGLHVKPVSVDEFRIAVAETYDVIIEPDSEQAYTVFAQSMDRTG
                     YARGTLAVQEGLSAPVPSPDPRPLIAMGDMGMDHGSMGGMDHGSMAGMDHGSMSGMDHG
                     SMQGGMAGMDHSQMAGMDHSGMAGMAGMAGAMQAHPASETNNPLVDMQTMTPTHKLDDP
                     GIGLRDNGRRVLTYSDLRSTFPDPDGREPSRTIELHLTGHMEKFSWSFDGIKFSDAEPL
                     RLKYGERVRITLVNDTMMTHPIHLHGMWSDLEDANGNFLVRKHTIDMPPGSKRSYRVTA
                     DALGRWAYHCHLLLHMETGMFREVRVDE"
     aSDomain        6834..8633
                     /aSDomain="TIGR01480"
                     /aSTool="tigrfam"
                     /description="copper_res_A: copper-resistance protein, CopA
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2051_0006"
                     /evalue="2.10E-301"
                     /identifier="TIGR01480"
                     /label="ctg1_2051"
                     /locus_tag="ctg1_2051"
                     /protein_end="602"
                     /protein_start="2"
                     /score="998.6"
                     /tool="antismash"
                     /translation="SKTTRRTFVKGLAATGIIGGLGLWRTPVWAVNSPGQPNVLTGNEF
                     DLFIGETPVNITGAARTAMTINGSLPGPILRWREGDTVTLRVRNRLKEDTSIHWHGIIL
                     PANMDGVPGLSFHGIAPDGMYEYKFKVNQNGTYWYHSHSGLQEQLGVYGALVIDAKEPE
                     PFSYDRDYVVLLSDWTDENPTRVLAKLKKQSDYYNQHKRTVGDFIDDVSEMGWSAAVAD
                     RKMWAEMKMSPTDLADVSGYTYTYLMNGQAPDGNWTGIFKPGEKIRLRFINASAMTYFD
                     VRIPGLKMTVVAADGLHVKPVSVDEFRIAVAETYDVIIEPDSEQAYTVFAQSMDRTGYA
                     RGTLAVQEGLSAPVPSPDPRPLIAMGDMGMDHGSMGGMDHGSMAGMDHGSMSGMDHGSM
                     QGGMAGMDHSQMAGMDHSGMAGMAGMAGAMQAHPASETNNPLVDMQTMTPTHKLDDPGI
                     GLRDNGRRVLTYSDLRSTFPDPDGREPSRTIELHLTGHMEKFSWSFDGIKFSDAEPLRL
                     KYGERVRITLVNDTMMTHPIHLHGMWSDLEDANGNFLVRKHTIDMPPGSKRSYRVTADA
                     LGRWAYHCHLLLHMETGMFREVRV"
     aSDomain        6840..6923
                     /aSDomain="TIGR01409"
                     /aSTool="tigrfam"
                     /description="TAT_signal_seq: Tat (twin-arginine
                     translocation) pathway signal sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_2051_0007"
                     /evalue="1.10E-04"
                     /identifier="TIGR01409"
                     /label="ctg1_2051"
                     /locus_tag="ctg1_2051"
                     /protein_end="32"
                     /protein_start="4"
                     /score="20.4"
                     /tool="antismash"
                     /translation="TTRRTFVKGLAATGIIGGLGLWRTPVWA"
     PFAM_domain     6984..7316
                     /aSDomain="Cu-oxidase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07732.17"
                     /description="Multicopper oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2051_0033"
                     /evalue="2.60E-39"
                     /label="ctg1_2051"
                     /locus_tag="ctg1_2051"
                     /protein_end="163"
                     /protein_start="52"
                     /score="134.1"
                     /tool="antismash"
                     /translation="ETPVNITGAARTAMTINGSLPGPILRWREGDTVTLRVRNRLKEDT
                     SIHWHGIILPANMDGVPGLSFHGIAPDGMYEYKFKVNQNGTYWYHSHSGLQEQLGVYGA
                     LVIDAKE"
     PFAM_domain     7341..7877
                     /aSDomain="Cu-oxidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00394.24"
                     /description="Multicopper oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2051_0034"
                     /evalue="1.30E-34"
                     /label="ctg1_2051"
                     /locus_tag="ctg1_2051"
                     /protein_end="350"
                     /protein_start="171"
                     /score="119.7"
                     /tool="antismash"
                     /translation="DYVVLLSDWTDENPTRVLAKLKKQSDYYNQHKRTVGDFIDDVSEM
                     GWSAAVADRKMWAEMKMSPTDLADVSGYTYTYLMNGQAPDGNWTGIFKPGEKIRLRFIN
                     ASAMTYFDVRIPGLKMTVVAADGLHVKPVSVDEFRIAVAETYDVIIEPDSEQAYTVFAQ
                     SMDRTGYARGTLAVQE"
     PFAM_domain     8286..8636
                     /aSDomain="Cu-oxidase_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07731.16"
                     /description="Multicopper oxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2051_0035"
                     /evalue="3.40E-25"
                     /label="ctg1_2051"
                     /locus_tag="ctg1_2051"
                     /protein_end="603"
                     /protein_start="486"
                     /score="88.5"
                     /tool="antismash"
                     /translation="PSRTIELHLTGHMEKFSWSFDGIKFSDAEPLRLKYGERVRITLVN
                     DTMMTHPIHLHGMWSDLEDANGNFLVRKHTIDMPPGSKRSYRVTADALGRWAYHCHLLL
                     HMETGMFREVRVD"
     CDS             8655..8966
                     /locus_tag="ctg1_2052"
                     /transl_table=11
                     /translation="MSTFMKRNALFGSAAMFSLLAVLHAPTSLAGEGHSEHEQHAAESA
                     APDASDKPADQSKGKAAGHQMDHGAMDHEGMNHDDMGHEKMMDKHGGTEAEAGSNHDH"
     CDS             8956..10047
                     /locus_tag="ctg1_2053"
                     /transl_table=11
                     /translation="MTTRFSRPSLIALAVSLSALSGGVTQAAEEMDHSAMGHGSMSMDH
                     SQMGHGSAKAPMEGMDHSKMDHGAMQGASGSMDHSQMGHGQSQEKAQAMDHSKMGHGAM
                     QGQMEGMDHSKMNHGSAEAPRTTSRTPIPVLTDADRQAAFPPLPGHKVHDSAINSFFLL
                     DQLEYQDADEGSTLAWDASGWVGGDINRVWFRSKGERTNGVTEDAELQLLYGRSIGPWW
                     DVVAGVRQDFKPESPQTWAAFGIQGMALYAFEAEATAFVGENGQTAARLEGEYDILLTN
                     RLILQPTAEMNFYGKNDPERGVGSGLANTELGLRLRYEIVRQFAPYIGVSWSRSYGNTA
                     DMVRDEGGDVDEARFVAGIRMWF"
     PFAM_domain     9430..10044
                     /aSDomain="CopB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05275.13"
                     /description="Copper resistance protein B precursor (CopB)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_2053_0036"
                     /evalue="3.00E-92"
                     /label="ctg1_2053"
                     /locus_tag="ctg1_2053"
                     /protein_end="363"
                     /protein_start="158"
                     /score="308.0"
                     /tool="antismash"
                     /translation="SFFLLDQLEYQDADEGSTLAWDASGWVGGDINRVWFRSKGERTNG
                     VTEDAELQLLYGRSIGPWWDVVAGVRQDFKPESPQTWAAFGIQGMALYAFEAEATAFVG
                     ENGQTAARLEGEYDILLTNRLILQPTAEMNFYGKNDPERGVGSGLANTELGLRLRYEIV
                     RQFAPYIGVSWSRSYGNTADMVRDEGGDVDEARFVAGIRMWF"
ORIGIN
        1 tgtcggtggc cacggtgaag aacatgaggc agaaccttgc ctttgcattc ctctacaacg
       61 cgatgggaat cccgctagcg gcggggctgc tgtacccgct gacggggcat cttctgtcgc
      121 ccttgattgc tgcgctggcg atgagtgtca gctcggcgtc ggtggtcttc aatgctctga
      181 ggttgaaatc aacggacatc ggataggctt ccataccacc gaccaggtga ttattcagaa
      241 gcgcatctga ccggaaaatg ccgtacggta gtttccggtc cgacctatct gtcgcaacac
      301 atagtgacga ggtgacgttc gatggactgt tgccgctgcg ggtaggagac tggtcgtcgt
      361 taacccatga ggactctccg tggcccgcat tcgcagactg attatcagca acttccgatc
      421 tatccaggcg ctcgactggg tgccggcccc aggaattaac tgcctcatag atcctggcga
      481 tagtggaaag tccagcattc tagatgcgat tgacctttgc gtcggcgccc gccgaggcgg
      541 cacgttcggc gacatggact tcttcgcatt aaacgtcgat gtacccatca ccatcagcgt
      601 ggcgcttggc gatctgccgt tatcgctgat ggatattgat gtctacggcg agttcttgcg
      661 tggattccat cccggtacgg gggaagtcga agacgaaccg cgagcggggc tggagaccgt
      721 catcaccttg cgtctgcaag ttggtgccga tttggagcct gtttggacac ttttctccga
      781 gcgcgcggag cagcagcaac ttgaacgcac tcttccctgg aaagaacgag cggcactagc
      841 gcccgcccgt atcggcagct ttgcgagctc gaacctgtcg tggagtcgtg gctcagtgct
      901 caatcgactt accgatgagc gcgccgagct tggtgctgaa ctggcgcgcg ccgctaggca
      961 agcaagagcg aactttggca atcaagcagc cgaacatctg acccagacgc ttgaggtcgt
     1021 gcaacgcaca gcacagcatc ttggcgtttc ggtcggggct atgcctcagg cgctccttga
     1081 cgcacattct gtgtcgattg gcgagggtgc gatcgcgctg cacagcgaca caggcattcc
     1141 ccttcgctcc cttggcacgg gctcgtcgcg attgctagtg gcagggttgc aaagagctgc
     1201 agctagcgcc gcgccaattg ctcttgtcga tgaggtggaa tatgggcttg aacctcatcg
     1261 gctcatgcga ttcttggact ccctgggcgc aaaggacgct gccgctccgt tgcaagtgtt
     1321 catgacgacg cactcgccgg tcgcgctgcg cgagctgtcc ggcagccagt tattcgttgt
     1381 tcggtcagca cctcagcgcc acagtgttat gccagctggg gaagccaacg aggtacaaag
     1441 tacccttcgg aaggaccccg aagcattcct cgccaaatcc atcatcgttt gcgagggggc
     1501 cagcgaggtt ggcttcgcgc gtggccttga ccaatggtgg gtcagtcttg gcgctacctc
     1561 attcctggcc catggcggcg cgtatgtgga cgccggcggg ggaagccccg ataacagtct
     1621 tatccgggga acagcacttc tgaacttggg ttaccgcgtg atggtttttg tagatgccga
     1681 caagccttcg accgcggggc tcgctgaagc attcttggcc gccggcgggc aaattcttac
     1741 atggcgacca ggtctcactc tggaggacga gatcttccgc catctcagtg agcaagcact
     1801 cgatgcactt ctggcgaaag ccgaaacaat agtgggtgca gagctgatga acgcacacat
     1861 tcagacgaag tcccaaggcc gcgtgacgct gaacgatatc cgagccaagc gactcgtgga
     1921 tgggtactca cctgagagac gagagctgct gggaaccgca tcccgtatcc gcaacagcgg
     1981 ctggttcaag tcgctgacaa cctatcagga ggttgcaagg gacatcgtcg gtccgtcttt
     2041 acagaacgcc gaactgggct tcatggcagt cacgaatcag ctctggacgt ttacaagtgc
     2101 cccctgagat tgatcttttc gctatcgagc gtggctccat aacggccccc gcaggttgtg
     2161 gaaaaacgca attgattgcc gagacgctca tcgcgcatac gcagagcaaa cccatcctcg
     2221 tcttgacaca tacgaacgcc ggcgttgcgg ccttacgggc gcgcctgaga cgagccggtg
     2281 ttcctaactc cgcatatcga gtctccacca ttgacggatt ctcgatgcgc ctgatcgcta
     2341 agttcccagc gcgaagcggc cataacccgc agatcctaca gctgcatcaa cccaatactg
     2401 actacccggc aattcgggag gccgccatgc agttgttgca ggccggtcac ctcgctcagc
     2461 cccttcgcgc cacctatgca cggttgcttg tcgacgagta ccaagactgc aacgtcgtcc
     2521 agcacgccat cgtgtctggt ttggcccagg tgcttccgac ctgcgtgctc ggtgacccga
     2581 tgcaagccat attcagcttc cgtggcaatc gactggtgca ttgggcgaat gaggtgcaac
     2641 ccctgtttcc cgcagcggga gagttgagga taccgtggcg ctggcggctg gctggagctg
     2701 agaacctcgg gcagtggctg ctcgccataa ggcaacaact tcaagctggt cagccggtgg
     2761 atctgcgcac ggctccagca gaagtgcgtt gggtgcagct aaacgccgga accgaagttc
     2821 agcagcgact ggtggccgcg agaaccgaag ctcccaacgc tcagggtagc gtcctcatca
     2881 tcggggactc catcaacgtg caaggtcgcc atcagctcac gagccagaca cccggtgcca
     2941 tggccgtaga agccgtcgac ctgagagatc tcgtcaactt cgccaggaac tttgacttgc
     3001 agggtgccaa tgctctggca caacttgtgg agtttgcttc cagcgtaatg acgggggtag
     3061 gtgcagcaaa cctgcgaacg cgcgtggagt cgctgcgtgc aggaagggcc cgaacgcctc
     3121 cgaccgcggc cgaggctgcg gcgatcgatt tcgtagcagc gccaacattg gggcaagcgc
     3181 tccgtgtgat cgatacgctc gctgagcagc acggggcacg tgtataccga ccggaggttc
     3241 tgtactgctg ccggtctgca atgcaagcgg tggtgggagg tgctgccgac tttctgagtg
     3301 cagccattca agcgcgagag cgcaatagac accttgcccg accgatcgca agacgctctg
     3361 taggcagcac attacttctc aaggggctgg aggcggatgt ctcggttgtc ctgcatcctg
     3421 agcttatgac cccccagaat ctatacgtcg cactgacgag gggcgcaagg catgtcgtgg
     3481 tgtgttcacc aacccccatc cttacgcccg tggtaaacgg ctgatccttt tgtagcgctt
     3541 acgggcttga ccttgccatc gtgtcaaggt cgatgctgtc cgtgcggtaa cttgagccgc
     3601 ggacgaaatg aggtgaaaga catgtttagt ctgagtgttg cggggatggg ctgtggcagt
     3661 tgcgtgagca aaatcacgaa ggccattcaa gctctggatc aggatgcacg agtagaagtg
     3721 gatcgagcgg ccggcaaggt caccgttgag agcacagaaa gtgccgaatc gatccgcgaa
     3781 ctcatccagg agcttggcta ttcggcccag gtcagcgctt gagcgctgac ctgctatccc
     3841 actaaatctc cagttctgag agctctttta gccctgggat actggtgacc tcgttggtca
     3901 taccttctga accatctcgg ccgcgaagcc agtttgagtg atcgcctggc tcgcgcattt
     3961 ccagcgtgtc atcatagggg taccgcttgc gcttgaacag gcttttcaat gcagcgaact
     4021 cgtggctttt ttcgtcttct atgccgacga cttctcctgc aagccgctcc cagtgaccaa
     4081 cgccgtcggc cagcattgcc tgataggtct ccgggtcaag caaggcttgc tgtttgaaat
     4141 gaatgatgcg gtgagtcata gaagcgctcg gagtggccaa agagagagcg ctagcctaaa
     4201 ggttccgggt cattcgtgta atagctggcc gcgctttagc aaaccgtcgt tgacccacaa
     4261 cttcaaccag gtcgcggctt gcaagggagc ttgctcgcca tgcgtggcgc tcaacgactc
     4321 gcagagttca gcgaacgatc cgccctcgat gagaaactgc aatgccgaag cctccgctgg
     4381 ctccaggctc cggtactggc agacgagttc atgacgccaa acaagacagg ctaggttcgt
     4441 tggcaggcgg gtaatatcag gcagcaagct gccggacttg gcggctttcc acaactccag
     4501 cgtgttgtac tgcagctgca accaccgggc agatgcagtc agggaaaccc tgagtgaaat
     4561 ccagtcttca gccgaaaaat cactcatggt ctccagcgaa agcgcttcga catcctgagc
     4621 gtcgaaggcc agtgtaaagg cccattccag ttccgcgagt tcgcgcatcg gcgatagttg
     4681 gggttcttcg acgtagctgc taatgaactc gggcagcttc tcgcccagcc agcgaatgct
     4741 gaaatgtcgt ggtggccagg cggccaagta ggccagtgcg agctgctcga atgattcgtt
     4801 gccgatccag tgaagcaggg cagggaagtc ttctcgcaag accgcaagca ggcgcgaacg
     4861 gtaagcgttg tggtagatct gcaggccttc gagagcactc agcgctgtgc tacctcggat
     4921 ctgctccaaa agctcgttgg agggcagggc actgtcacct gtcaggtaag tttcaaatgc
     4981 agtctgtagg gcgatcaggc tcaaggggtg gcccccgata tcacagattt ggcgatagca
     5041 cgggcatgtg ctaattcgga caacagctct tccagcggcg gaaactggtc atcccgctcg
     5101 atcaaggtcg atgtcgggcc caagtagctc aaagtcttgc tgtagagaga ccaaaccgga
     5161 tcagcgatgg gctggtcatg ggtgtcgatg aggtactgcc cgtaatcgct gtgcccggcc
     5221 aggtgaattt gccgaatccg ctcgtgcggc aattccatga tgaactgcca agggtcgaaa
     5281 ccctggttgc gcgaactgac gtagacgttg ttcacgtcga gaagcagctc gcacccggtc
     5341 aggtaactga gctccgagag gaactgagac tcgctcatgc tggatgttgt ccactgcacg
     5401 taggaggaaa cgttctccag cacgatggga cgttccaaaa catcctgcac caagcgcacc
     5461 cgggccgcga catgcagcag gctctcctgg gtaaacggca gcggtagcag atcgtgaagt
     5521 tgatgggcgt tgcctcgact ccagcacagg tgatcagaca cccactgagg ctgcacccga
     5581 tccgccagct gcttgagctg tcgtaggtag tctatgtcca aggcatgtga gccgccaatc
     5641 gaaagagata ctccgtgcat caccaggggg tagtgctcgc cgatcgcatc aaggaagtag
     5701 agagccttgc cgccctccac caggtaattc tcggaaatga tctcgaacca gtcgaccgca
     5761 ggccgttcct ccaggatctg ccggtaatac tcgttacgaa ggccaagacc gaaacccaga
     5821 gttttgcgct tactcattcg agactccagc aggggagtgg gcatgcactc ccctgaaccg
     5881 ccttattcgc tggttttgcc accggcttcg tcacatttgg tctgggtcat caacttgaac
     5941 ccttggcctt tgcattcgcc ttggcctttg cagtcgtttt tcgcggtcat gcagtcgttc
     6001 tgccctttgc aaccattgat cccgaagcac ttcacttctg ctgctttggt ttcctgagca
     6061 gcctggacgg gcagggtgga gaacaggctg gcggccacca gagccaaggc ggcaccggta
     6121 gctacgttgg atttgttcga catagtggct atctctcttg attgtttgat ggtcgcgatc
     6181 cgtcggtgcg aatgaacgag ttagctcagg cattgctacc gatcaggccc atggaatccg
     6241 caaggctgcg cgggcaggaa gacagtaccg agccttcagg agggcctaca agaaagaaat
     6301 agcaaactga cagaactgta atgttcggat caggttgctg acagggcgtc gtggttaacg
     6361 tagcagcgag cttaacgctc gtccccacta gttacagggg cttctaaact tctgaggatt
     6421 aacgaaatga aatcgatcaa aaccctgttt gtagttgctg ccctgagtgt ttccagcctg
     6481 gcgatggccg aaggcggtgc tgatcgcacg tttgcacgca tggagcaggc acgccagacg
     6541 tctctggagg cctaccgggt ggcccagcag cagaaagttg aggctcctgt agccagcagt
     6601 ccaaccgagc aagcagagca caccaactgc tgaagtcatc taccttacag aaatgtaatc
     6661 acccggatgg ttgaaatatg gcagtttcat actgctcatc gtcggtaagg cattgtgcaa
     6721 tgcaccgacg tggaaagttg aggggtaaat ccccgacatt gaagcagcca tgaacccgag
     6781 accgggcaca ccatcaccgg ctcatttgac ggattggaca aaacggcatg caaagcaaaa
     6841 ccacaaggcg caccttcgtc aaaggcctgg cagccaccgg tattatcggc ggacttggcc
     6901 tgtggcgcac gccggtctgg gcggtgaaca gccccggcca gcccaacgta ctgactggta
     6961 acgaattcga cctattcatc ggtgaaaccc cggtgaacat caccggcgca gcgcgcacgg
     7021 ccatgaccat caacggctcg ctccctgggc cgattcttcg ttggcgcgaa ggcgataccg
     7081 tcacattgcg cgtgcgcaac cgcctcaagg aggacacctc catccattgg cacggcatca
     7141 tcctgccggc gaacatggat ggtgttcctg gcctgagctt ccatggcatc gcccctgatg
     7201 gcatgtatga gtacaagttc aaggtcaacc agaacggcac ctactggtat cacagccatt
     7261 ctgggctcca ggagcagctc ggcgtatacg gtgcgctggt catcgatgcc aaggagcccg
     7321 agcccttcag ttacgaccgt gattacgtcg tgttgctgag cgactggacg gatgaaaatc
     7381 caacgcgggt actggccaag ctcaagaaac agtcggacta ctacaaccag cacaaacgca
     7441 ccgttggtga cttcatcgat gacgtaagcg agatgggttg gtccgccgcc gtagccgacc
     7501 gtaagatgtg ggccgaaatg aagatgagcc cgactgatct cgccgacgtc agtggctaca
     7561 cctacaccta cctgatgaac ggccaggcac ctgatggcaa ctggaccggc atattcaaac
     7621 cgggcgagaa gattcgtctg cgtttcatca atgcctcggc catgacgtac ttcgatgtgc
     7681 gcatcccagg cctgaagatg actgtggttg cggccgatgg tctgcacgtc aaaccggtca
     7741 gcgtcgacga gttccgtatc gccgtggccg agacctacga cgtgatcatc gaaccagaca
     7801 gcgaacaggc ctataccgtg tttgcccaat ccatggaccg cactggctat gcgcgcggca
     7861 cccttgcggt acaggaaggg ttgagtgcac cggtaccaag ccctgacccg cgcccactga
     7921 ttgccatggg tgacatgggc atggaccacg gcagcatggg cggcatggat catgggagca
     7981 tggccgggat ggatcacggc agtatgtcgg gcatggatca tgggagcatg cagggtggca
     8041 tggccggcat ggatcacagc cagatggctg gaatggatca ttcgggcatg gcaggcatgg
     8101 caggcatggc aggtgccatg caggcacacc cagcctcaga gaccaacaac ccgctggtcg
     8161 atatgcaaac catgacacca acgcataagt tggacgaccc aggtattggt ttgcgagaca
     8221 acggccgacg cgtcctcacg tactctgacc tgcgcagcac cttccctgat ccggacgggc
     8281 gtgagccaag tcgcaccatc gagctgcacc tcaccgggca tatggagaaa ttctcctggt
     8341 ccttcgatgg aatcaagttc tctgacgccg agcctctgcg cctcaagtac ggcgagcgtg
     8401 ttcgcatcac gctggtcaac gacaccatga tgactcaccc gatccatctt catggcatgt
     8461 ggagtgatct ggaggatgcg aacggcaatt tcctggtgcg taaacacacc atcgacatgc
     8521 cgccaggttc caagcgcagc tatcgggtga ccgccgatgc gttggggcgt tgggcctatc
     8581 actgccacct gttgctccac atggaaacgg gcatgttccg tgaagtccgt gtggatgagt
     8641 aaaggagatt tctgatgagt acttttatga agcgtaatgc cctgtttggc agcgcagcga
     8701 tgttcagtct tttggctgtt ctgcacgcgc cgacgtcatt ggcaggtgag gggcacagcg
     8761 agcacgaaca acatgctgcc gagtcggctg cgcccgacgc cagtgacaag cctgcagatc
     8821 aatcgaaagg caaggccgct ggccatcaga tggatcatgg cgccatggat catgagggta
     8881 tgaaccatga cgatatgggg cacgagaaga tgatggataa gcatggcggc accgaagccg
     8941 aagcaggttc gaaccatgac cactaggttt tcacgcccgt ccctcatagc gctggccgtg
     9001 tcgctgagtg cactcagcgg cggcgttacc caggctgcgg aagaaatgga tcattcggca
     9061 atggggcacg gctccatgtc gatggaccac agccagatgg gccacggttc cgccaaagcg
     9121 ccgatggagg gcatggatca cagcaagatg gaccatggtg ccatgcaggg tgcttcgggc
     9181 agcatggatc atagccagat gggccacggc cagagccaag agaaggccca ggctatggat
     9241 cacagcaaga tggggcatgg cgccatgcaa ggacagatgg agggcatgga tcattcaaag
     9301 atgaaccatg gctccgctga agccccgaga accaccagcc gtacgccgat tcccgttctg
     9361 acggatgctg atcgccaagc ggctttcccg ccattacctg gccacaaggt tcacgacagc
     9421 gccatcaaca gttttttcct gctcgatcag ctcgaatacc aggacgcaga tgagggcagc
     9481 accctggcct gggatgcgtc gggctgggta ggcggtgata tcaaccgggt ctggttccgc
     9541 tccaaaggcg agcgtaccaa cggcgtgacc gaggatgctg aattacagct gctgtacggc
     9601 cgctcgatcg gcccttggtg ggatgtcgtc gcgggcgttc gccaggactt caaaccggag
     9661 tcgccgcaga cttgggccgc cttcggtatc cagggcatgg cgctttacgc ctttgaggcc
     9721 gaagccacgg ccttcgtcgg cgagaatggc caaactgctg cccgactgga gggcgagtac
     9781 gacattctgc tgaccaaccg gctgattctc cagccaactg ccgaaatgaa cttctacggc
     9841 aagaacgatc ctgagcgagg tgtggggtct gggttggcaa ataccgagct cggcttgcgt
     9901 ctgcgttacg agattgtcag gcagtttgcc ccctatatcg gggtttcctg gagccgctcc
     9961 tatggcaaca cggcagacat ggtgcgcgac gagggcggtg atgtagacga ggcgcgtttt
    10021 gtcgccggta tccggatgtg gttttgagaa cctgacatga aaagaacaat taaaactttg
    10081 gtggcggccg gcgtggtcgg tagcacagct gtcctggccg gcgcctactt tggcgtggtc
    10141 aacgtggggg ccgacgatcc ccattttcct gcagtgcatg cgtttctcac gatggcccgt
    10201 gaccgctcta tcgaagtccg ttcgcgggac atcgaggttc ccaacctgga tgatcaagct
    10261 cttattcgcg ccggtgcggg caactacaac tccatgtgta tcggctgtca tttggcgcca
    10321 ggtgtggcgg agaccgagct aagccaatcg ctttatcctg cgccccccaa cctcgccaag
    10381 atcggtgtcg atggcaatcc gtcagcagcg ttctgggtga tcaagcatgg catcaaggca
    10441 acgggtatgc ctgcgtgggg caagagcatg ggagacgagt acatctgggg catggttgcc
    10501 ttcctcaacc aactgccgac gatggatgcc aagcaatacc aaacactcgt cgcatccagt
    10561 ggcggccatc agcacggtgg tggggaaacg cagatgcata accatgaagg acagcacggc
    10621 gacaacaagc ctggccatca tgacaatagt ggcggtggcg atgaccatca tggatcaggt
    10681 gatgctggag agcctggtca tcacgatgcc gcggctacgg atagcgaggg tggctccgca
    10741 cctaaggcag gtcaccattc ggatatgagt ggcgatgacc accatgctgg ggatgaggcg
    10801 tcgtccaacg gaggtgatca tcacgccgag caggctc
//
