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Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP013124.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | betalactone | 1,670,477 | 1,697,753 | tetarimycin A / tetarimycin B | Polyketide:Type II | 5%
Region 1.2 | NAGGN | 1,848,645 | 1,863,544 |
Region 1.3 | NRPS | 1,953,577 | 2,019,213 | pyoverdin | NRP | 6%
Region 1.4 | redox-cofactor | 2,250,309 | 2,272,554 | lankacidin C | NRP + Polyketide | 13%
Region 1.5 | betalactone | 2,354,944 | 2,387,345 | fengycin | NRP | 20%
Region 1.6 | RiPP-like | 3,365,968 | 3,376,810 |
Region 1.7 | arylpolyene,resorcinol | 4,433,523 | 4,486,392 | APE Vf | Other | 45%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | betalactone | 1,670,477 | 1,697,753 | tetarimycin A / tetarimycin B | Polyketide:Type II | 5%
Region 1.2 | NAGGN | 1,848,645 | 1,863,544 |
Region 1.3 | NRPS | 1,953,577 | 2,019,213 | pyoverdin | NRP | 6%
Region 1.4 | redox-cofactor | 2,250,309 | 2,272,554 | lankacidin C | NRP + Polyketide | 13%
Region 1.5 | betalactone | 2,354,944 | 2,387,345 | fengycin | NRP | 20%
Region 1.6 | RiPP-like | 3,365,968 | 3,376,810 |
Region 1.7 | arylpolyene,resorcinol | 4,433,523 | 4,486,392 | APE Vf | Other | 45%

No secondary metabolite regions were found in these records:
  NZ_CP013125.1

Compact view
NZ_CP013124.1 - Region 1 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,670,477 - 1,697,753 nt. (total: 27,277 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000258.1 |  | 0.18 | Polyketide | prodigiosin | Serratia sp.
BGC0000260.1 |  | 0.17 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000923.1 |  | 0.15 | Other | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0001220.1 |  | 0.14 | NRP | aculeacin A | Aspergillus japonicus
BGC0001895.1 |  | 0.14 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000342.1 |  | 0.14 | NRP | enniatin | Fusarium equiseti
BGC0001128.1 |  | 0.14 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001140.1 |  | 0.14 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000218.1 |  | 0.14 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000193.1 |  | 0.14 | Polyketide | aclacinomycin | Streptomyces galilaeus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000258.1 |  | 0.50 | Polyketide | prodigiosin | Serratia sp.
BGC0000260.1 |  | 0.49 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000923.1 |  | 0.45 | Other | paerucumarin | Pseudomonas aeruginosa PAO1
BGC0001220.1 |  | 0.43 | NRP | aculeacin A | Aspergillus japonicus
BGC0001895.1 |  | 0.43 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000342.1 |  | 0.43 | NRP | enniatin | Fusarium equiseti
BGC0001128.1 |  | 0.43 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001140.1 |  | 0.43 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000218.1 |  | 0.43 | Polyketide | doxorubicin | Streptomyces peucetius
BGC0000193.1 |  | 0.42 | Polyketide | aclacinomycin | Streptomyces galilaeus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013124.1 - Region 2 - NAGGN
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,848,645 - 1,863,544 nt. (total: 14,900 nt) Show pHMM detection rules used
NAGGN: ((TIGR03104 or cds(GATase_7 and Asn_synthase)) and TIGR03103 and (TIGR03106 or Peptidase_M42))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAGGN | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000885.1 |  | 0.17 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000846.1 |  | 0.14 | Other | tabtoxin | Pseudomonas syringae
BGC0000937.1 |  | 0.14 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000781.1 |  | 0.14 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001374.1 |  | 0.14 | Other | thienodolin | Streptomyces albogriseolus
BGC0000860.1 |  | 0.11 | Other | ectoine | Methylarcula marina
BGC0000854.1 |  | 0.11 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.11 | Other | ectoine | Methylophaga alcalica
BGC0001739.1 |  | 0.10 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000254.1 |  | 0.08 | Polyketide | oxytetracycline | Streptomyces rimosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000885.1 |  | 0.48 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000846.1 |  | 0.44 | Other | tabtoxin | Pseudomonas syringae
BGC0000937.1 |  | 0.43 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000781.1 |  | 0.43 | Saccharide | O-antigen | Pseudomonas aeruginosa
BGC0001374.1 |  | 0.43 | Other | thienodolin | Streptomyces albogriseolus
BGC0000860.1 |  | 0.38 | Other | ectoine | Methylarcula marina
BGC0000854.1 |  | 0.38 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.38 | Other | ectoine | Methylophaga alcalica
BGC0001739.1 |  | 0.36 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000254.1 |  | 0.31 | Polyketide | oxytetracycline | Streptomyces rimosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013124.1 - Region 3 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,953,577 - 2,019,213 nt. (total: 65,637 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.39 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.38 | NRP | sevadicin | Paenibacillus larvae
BGC0001671.1 |  | 0.30 | NRP | monobactam | Agrobacterium tumefaciens
BGC0001833.1 |  | 0.29 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001790.1 |  | 0.29 | NRP | sulfazecin | Pseudomonas acidophila
BGC0001502.1 |  | 0.29 | NRP | amonabactin P 750 | Aeromonas hydrophila subsp. hydrophila ATCC 7966
BGC0001135.1 |  | 0.28 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001826.1 |  | 0.28 | NRP | xeneprotides A-C | Xenorhabdus sp. KJ12.1
BGC0001128.1 |  | 0.28 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000351.1 |  | 0.28 | NRP | exochelin | Mycolicibacterium smegmatis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.71 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.70 | NRP | sevadicin | Paenibacillus larvae
BGC0001671.1 |  | 0.63 | NRP | monobactam | Agrobacterium tumefaciens
BGC0001833.1 |  | 0.63 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001790.1 |  | 0.63 | NRP | sulfazecin | Pseudomonas acidophila
BGC0001502.1 |  | 0.63 | NRP | amonabactin P 750 | Aeromonas hydrophila subsp. hydrophila ATCC 7966
BGC0001135.1 |  | 0.62 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001826.1 |  | 0.62 | NRP | xeneprotides A-C | Xenorhabdus sp. KJ12.1
BGC0001128.1 |  | 0.62 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000351.1 |  | 0.62 | NRP | exochelin | Mycolicibacterium smegmatis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1953576 - 2019213:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (D-asn - X) + (D-ser - X - ser - D-X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1821: pk - asn - X
  Search NORINE for peptide: strict or relaxed
  CAL_domain (38..460): pk
  minowa: NH2
  Prediction, score:
    NH2: 147.5
    fatty_acid: 21.6
    AHBA: 5.5
    shikimic_acid: 0.0
    Acetyl-CoA: -0.8
  AMP-binding (1125..1520): asn
  NRPSPredictor2: asn
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asp
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKIGhVGK
    Nearest Stachelhaus code:
      asn
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (2615..3018): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWeLtadDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      60% (weak)
ctg1_1822: ser - X - ser - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (508..905): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1976..2375): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgEacAgVtK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      50% (weak)
  AMP-binding (3022..3419): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (4064..4463): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgEacAgVtK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      50% (weak)

NZ_CP013124.1 - Region 4 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,250,309 - 2,272,554 nt. (total: 22,246 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.18 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001120.1 |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.14 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.14 | Other | dehydrophos | Streptomyces luridus
BGC0000874.1 |  | 0.13 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001739.1 |  | 0.13 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001865.1 |  | 0.12 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001338.1 |  | 0.12 | Polyketide | citrinin | Monascus ruber
BGC0001057.1 |  | 0.11 | NRP, Polyketide | zearalenone | Fusarium graminearum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001441.1 |  | 0.49 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001120.1 |  | 0.45 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001925.1 |  | 0.44 | Alkaloid | altemicidin, SB-203207, SB-203208 | Streptomyces sp.
BGC0000703.1 |  | 0.44 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000897.1 |  | 0.43 | Other | dehydrophos | Streptomyces luridus
BGC0000874.1 |  | 0.42 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001739.1 |  | 0.41 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001865.1 |  | 0.39 | Polyketide | elsinochrome C | Parastagonospora nodorum SN15
BGC0001338.1 |  | 0.39 | Polyketide | citrinin | Monascus ruber
BGC0001057.1 |  | 0.39 | NRP, Polyketide | zearalenone | Fusarium graminearum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013124.1 - Region 5 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,354,944 - 2,387,345 nt. (total: 32,402 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001983.1 |  | 0.23 | Other | triacsins | Kitasatospora aureofaciens
BGC0000890.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000891.1 |  | 0.22 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.22 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001739.1 |  | 0.21 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000234.1 |  | 0.20 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000260.1 |  | 0.20 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000774.1 |  | 0.20 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000220.1 |  | 0.20 | Polyketide | enterocin | Streptomyces maritimus
BGC0001343.1 |  | 0.19 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001983.1 |  | 0.56 | Other | triacsins | Kitasatospora aureofaciens
BGC0000890.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000891.1 |  | 0.55 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.55 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001739.1 |  | 0.54 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000234.1 |  | 0.53 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000260.1 |  | 0.53 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0000774.1 |  | 0.52 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris
BGC0000220.1 |  | 0.52 | Polyketide | enterocin | Streptomyces maritimus
BGC0001343.1 |  | 0.52 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP013124.1 - Region 6 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 3,365,968 - 3,376,810 nt. (total: 10,843 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
NZ_CP013124.1 - Region 7 - arylpolyene,resorcinol
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,433,523 - 4,486,392 nt. (total: 52,870 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)
resorcinol: DarB

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | resorcinol | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001723.1 |  |  | 0.45 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000234.1 |  |  | 0.45 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001366.1 |  |  | 0.45 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0000228.1 |  |  | 0.44 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000248.1 |  |  | 0.42 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000272.1 |  |  | 0.42 | Polyketide | spore pigment | Streptomyces collinus
BGC0000194.1 |  |  | 0.40 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000719.1 |  |  | 0.38 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000891.1 |  |  | 0.37 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0000221.1 |  |  | 0.37 | Polyketide | erdacin | uncultured soil bacterium V167

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000234.1 |  | 0.56 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0001366.1 |  | 0.55 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0000228.1 |  | 0.55 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000194.1 |  | 0.55 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)
BGC0000719.1 |  | 0.54 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae
BGC0000272.1 |  | 0.54 | Polyketide | spore pigment | Streptomyces collinus
BGC0000889.1 |  | 0.54 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0000261.1 |  | 0.53 | Polyketide | R1128 | Streptomyces sp. R1128

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names