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Overview
1.1
1.2
1.3
1.4
1.5

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP064354.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 589,898 | 633,496 | APE Vf | Other | 40%
Region 1.2 | betalactone | 1,831,720 | 1,854,947 | fengycin | NRP | 20%
Region 1.3 | siderophore | 2,408,699 | 2,423,364 | xanthoferrin | Other | 100%
Region 1.4 | NAGGN | 3,537,092 | 3,551,824 |
Region 1.5 | redox-cofactor | 4,831,920 | 4,854,082 | lankacidin C | NRP + Polyketide | 13%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene | 589,898 | 633,496 | APE Vf | Other | 40%
Region 1.2 | betalactone | 1,831,720 | 1,854,947 | fengycin | NRP | 20%
Region 1.3 | siderophore | 2,408,699 | 2,423,364 | xanthoferrin | Other | 100%
Region 1.4 | NAGGN | 3,537,092 | 3,551,824 |
Region 1.5 | redox-cofactor | 4,831,920 | 4,854,082 | lankacidin C | NRP + Polyketide | 13%

No secondary metabolite regions were found in these records:
  NZ_CP064355.1

Compact view
NZ_CP064354.1 - Region 1 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
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Location: 589,898 - 633,496 nt. (total: 43,599 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001723.1 |  | 0.25 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000889.1 |  | 0.24 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001366.1 |  | 0.24 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0000231.1 |  | 0.24 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.23 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.22 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002029.1 |  | 0.22 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.22 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001897.1 |  | 0.22 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000889.1 |  | 0.57 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0001366.1 |  | 0.57 | Polyketide | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0000231.1 |  | 0.57 | Polyketide | griseusin | Streptomyces griseus
BGC0000234.1 |  | 0.56 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000228.1 |  | 0.56 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0002029.1 |  | 0.55 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.55 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001897.1 |  | 0.55 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP064354.1 - Region 2 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,831,720 - 1,854,947 nt. (total: 23,228 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000649.1 |  | 0.20 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000234.1 |  | 0.20 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000890.1 |  | 0.20 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000312.1 |  | 0.20 | NRP | bassianolide | Beauveria bassiana
BGC0000891.1 |  | 0.20 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.20 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001897.1 |  | 0.18 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001140.1 |  | 0.15 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000131.1 |  | 0.15 | Polyketide | pyrrolomycin | Streptomyces sp. UC 11065
BGC0000632.1 |  | 0.15 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000649.1 |  | 0.53 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000234.1 |  | 0.53 | Polyketide | jadomycin | Streptomyces venezuelae ATCC 10712
BGC0000890.1 |  | 0.52 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas phenolica O-BC30
BGC0000312.1 |  | 0.52 | NRP | bassianolide | Beauveria bassiana
BGC0000891.1 |  | 0.52 | Other (Aminocoumarin) | pentabromopseudilin | Pseudoalteromonas luteoviolacea 2ta16
BGC0001465.1 |  | 0.52 | Other | bromopyrroles/bromophenols | Marinomonas mediterranea MMB-1
BGC0001897.1 |  | 0.50 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0001140.1 |  | 0.45 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000131.1 |  | 0.45 | Polyketide | pyrrolomycin | Streptomyces sp. UC 11065
BGC0000632.1 |  | 0.45 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP064354.1 - Region 3 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,408,699 - 2,423,364 nt. (total: 14,666 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001408.1 |  | 0.53 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1 |  | 0.51 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000942.1 |  | 0.25 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000947.1 |  | 0.24 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001387.1 |  | 0.16 | Other | nucleocidin | Streptomyces calvus
BGC0000943.1 |  | 0.13 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001690.1 |  | 0.06 | Polyketide | natamycin | Streptomyces gilvosporeus
BGC0001093.1 |  | 0.05 | NRP, Polyketide | disorazol A | Sorangium cellulosum
BGC0001770.1 |  | 0.05 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0001908.1 |  | 0.05 | Polyketide | sceliphrolactam | Streptomyces sp. SD85

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001408.1 |  | 0.80 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000946.1 |  | 0.79 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000942.1 |  | 0.59 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000947.1 |  | 0.57 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001387.1 |  | 0.46 | Other | nucleocidin | Streptomyces calvus
BGC0000943.1 |  | 0.42 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001690.1 |  | 0.25 | Polyketide | natamycin | Streptomyces gilvosporeus
BGC0001093.1 |  | 0.23 | NRP, Polyketide | disorazol A | Sorangium cellulosum
BGC0001770.1 |  | 0.22 | Polyketide | sceliphrolactam | Streptomyces sp. SD85
BGC0001908.1 |  | 0.22 | Polyketide | sceliphrolactam | Streptomyces sp. SD85

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP064354.1 - Region 4 - NAGGN
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,537,092 - 3,551,824 nt. (total: 14,733 nt) Show pHMM detection rules used
NAGGN: ((TIGR03104 or cds(GATase_7 and Asn_synthase)) and TIGR03103 and (TIGR03106 or Peptidase_M42))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NAGGN | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000905.1 |  | 0.18 | Other | heme D1 | Heliobacillus mobilis
BGC0000906.1 |  | 0.18 | Other | heme D1 | Heliophilum fasciatum
BGC0000846.1 |  | 0.18 | Other | tabtoxin | Pseudomonas syringae
BGC0000885.1 |  | 0.15 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000937.1 |  | 0.14 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001374.1 |  | 0.14 | Other | thienodolin | Streptomyces albogriseolus
BGC0001739.1 |  | 0.12 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000796.1 |  | 0.09 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001395.1 |  | 0.09 | Other | teichomycin | Actinoplanes teichomyceticus
BGC0000254.1 |  | 0.08 | Polyketide | oxytetracycline | Streptomyces rimosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000905.1 |  | 0.50 | Other | heme D1 | Heliobacillus mobilis
BGC0000906.1 |  | 0.50 | Other | heme D1 | Heliophilum fasciatum
BGC0000846.1 |  | 0.50 | Other | tabtoxin | Pseudomonas syringae
BGC0000885.1 |  | 0.45 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000937.1 |  | 0.43 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0001374.1 |  | 0.43 | Other | thienodolin | Streptomyces albogriseolus
BGC0001739.1 |  | 0.40 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0000796.1 |  | 0.33 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0001395.1 |  | 0.32 | Other | teichomycin | Actinoplanes teichomyceticus
BGC0000254.1 |  | 0.31 | Polyketide | oxytetracycline | Streptomyces rimosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP064354.1 - Region 5 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,831,920 - 4,854,082 nt. (total: 22,163 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000258.1 |  | 0.22 | Polyketide | prodigiosin | Serratia sp.
BGC0000259.1 |  | 0.21 | Polyketide | prodigiosin | Serratia marcescens
BGC0000260.1 |  | 0.20 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0001441.1 |  | 0.18 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000723.1 |  | 0.16 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0001223.1 |  | 0.15 | Other | hydroxysporine | uncultured bacterium
BGC0000703.1 |  | 0.15 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001917.1 |  | 0.14 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000919.1 |  | 0.14 | Other | phaseolotoxin | Pseudomonas syringae
BGC0001440.1 |  | 0.14 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000258.1 |  | 0.55 | Polyketide | prodigiosin | Serratia sp.
BGC0000259.1 |  | 0.54 | Polyketide | prodigiosin | Serratia marcescens
BGC0000260.1 |  | 0.52 | Polyketide | prodigiosin | Hahella chejuensis KCTC 2396
BGC0001441.1 |  | 0.50 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000723.1 |  | 0.46 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0001223.1 |  | 0.45 | Other | hydroxysporine | uncultured bacterium
BGC0000703.1 |  | 0.45 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001917.1 |  | 0.44 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000919.1 |  | 0.44 | Other | phaseolotoxin | Pseudomonas syringae
BGC0001440.1 |  | 0.44 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names