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Overview
1.1
1.2
1.3
1.4
1.5
2.1
2.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP040990.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | betalactone | 7,785 | 35,353 |
Region 1.2 | RiPP-like | 589,765 | 600,628 |
Region 1.3 | NRPS-like | 2,165,265 | 2,208,261 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 5%
Region 1.4 | arylpolyene | 2,496,517 | 2,540,112 | APE Vf | Other | 90%
Region 1.5 | NRPS | 2,542,918 | 2,587,579 | vulnibactin | NRP | 37%

NZ_CP040991.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | ectoine | 555,515 | 565,907 | ectoine | Other | 66%
Region 2.2 | hserlactone | 1,218,339 | 1,238,920 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | betalactone | 7,785 | 35,353 |
Region 1.2 | RiPP-like | 589,765 | 600,628 |
Region 1.3 | NRPS-like | 2,165,265 | 2,208,261 | lipopolysaccharide | Saccharide:Lipopolysaccharide | 5%
Region 1.4 | arylpolyene | 2,496,517 | 2,540,112 | APE Vf | Other | 90%
Region 1.5 | NRPS | 2,542,918 | 2,587,579 | vulnibactin | NRP | 37%
Region 2.1 | ectoine | 555,515 | 565,907 | ectoine | Other | 66%
Region 2.2 | hserlactone | 1,218,339 | 1,238,920 |

No secondary metabolite regions were found in these records:
  NZ_CP040989.1

Compact view
NZ_CP040990.1 - Region 1 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 7,785 - 35,353 nt. (total: 27,569 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.21 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  | 0.20 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001441.1 |  | 0.16 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001758.1 |  | 0.14 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0000632.1 |  | 0.13 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0002009.1 |  | 0.13 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000938.1 |  | 0.13 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000805.1 |  | 0.13 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0001895.1 |  | 0.13 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000595.1 |  | 0.13 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.53 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001859.1 |  | 0.52 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0001441.1 |  | 0.46 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001758.1 |  | 0.43 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0000632.1 |  | 0.42 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica
BGC0002009.1 |  | 0.42 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0000938.1 |  | 0.41 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000805.1 |  | 0.41 | Saccharide | moenomycin | Streptomyces viridosporus ATCC 14672
BGC0001895.1 |  | 0.41 | Polyketide | huanglongmycin A, huanglongmycin B, huanglongmycin C | Streptomyces sp. CB09001
BGC0000595.1 |  | 0.41 | RiPP | SCO-2138 | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040990.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 589,765 - 600,628 nt. (total: 10,864 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001133.1 |  | 0.05 | NRP | taxlllaid A | Xenorhabdus bovienii SS-2004

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001133.1 |  | 0.22 | NRP | taxlllaid A | Xenorhabdus bovienii SS-2004

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040990.1 - Region 3 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,165,265 - 2,208,261 nt. (total: 42,997 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001900.1 |  | 0.33 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001168.1 |  | 0.33 | NRP | livipeptin | Streptomyces lividans 1326
BGC0001516.1 |  | 0.29 | NRP | aspergillic acid | Aspergillus flavus NRRL3357
BGC0001599.1 |  | 0.28 | NRP | fragin | Burkholderia cenocepacia H111
BGC0000343.1 |  | 0.28 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001399.1 |  | 0.25 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001343.1 |  | 0.22 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000427.1 |  | 0.22 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000375.1 |  | 0.21 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001591.1 |  | 0.21 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001900.1 |  | 0.66 | NRP | fragin | Burkholderia cenocepacia H111
BGC0001168.1 |  | 0.66 | NRP | livipeptin | Streptomyces lividans 1326
BGC0001516.1 |  | 0.63 | NRP | aspergillic acid | Aspergillus flavus NRRL3357
BGC0001599.1 |  | 0.62 | NRP | fragin | Burkholderia cenocepacia H111
BGC0000343.1 |  | 0.61 | NRP | enterobactin | Pseudomonas sp. J465
BGC0001399.1 |  | 0.58 | NRP | fellutamide B | Aspergillus nidulans FGSC A4
BGC0001343.1 |  | 0.56 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000427.1 |  | 0.55 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000375.1 |  | 0.54 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001591.1 |  | 0.54 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 2165264 - 2208261:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1998: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (7..399): X
  NRPSPredictor2: val, leu, ile, abu, iva
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWfFayIfK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      60% (weak)
ctg1_2004: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (64..501): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      vVyFfAHwAK
    Nearest Stachelhaus code:
      pro
    Stachelhaus code match:
      60% (weak)

NZ_CP040990.1 - Region 4 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,496,517 - 2,540,112 nt. (total: 43,596 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000837.1 |  | 0.51 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002008.1 |  | 0.32 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.30 | Other | APE Ec | Escherichia coli CFT073
BGC0000889.1 |  | 0.27 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002029.1 |  | 0.26 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.26 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001723.1 |  | 0.25 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000221.1 |  | 0.24 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000231.1 |  | 0.24 | Polyketide | griseusin | Streptomyces griseus
BGC0000194.1 |  | 0.24 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000837.1 |  | 0.79 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0002008.1 |  | 0.65 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.64 | Other | APE Ec | Escherichia coli CFT073
BGC0000889.1 |  | 0.60 | Other | bagremycin A, bagremycin B | Streptomyces sp. WK-5344
BGC0002029.1 |  | 0.60 | Other | bagremycin A, bagremycin B, bagremycin C, bagremycin E, bagremycin F, bagremycin G, ferroverdin A, ferroverdin B, ferroverdin C | Streptomyces lunaelactis
BGC0001592.1 |  | 0.60 | Other | ferroverdin | Streptomyces lunaelactis
BGC0001723.1 |  | 0.58 | Polyketide | oviedomycin | Streptomyces antibioticus
BGC0000221.1 |  | 0.58 | Polyketide | erdacin | uncultured soil bacterium V167
BGC0000231.1 |  | 0.58 | Polyketide | griseusin | Streptomyces griseus
BGC0000194.1 |  | 0.57 | Polyketide | actinorhodin | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040990.1 - Region 5 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,542,918 - 2,587,579 nt. (total: 44,662 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001302.1 |  | 0.25 | Other | lomofungin | Streptomyces lomondensis
BGC0000454.1 |  | 0.22 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0001343.1 |  | 0.22 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001641.1 |  | 0.21 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000349.1 |  | 0.21 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0000401.1 |  | 0.21 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001833.1 |  | 0.21 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.21 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001517.1 |  | 0.21 | NRP | asperphenamate | Aspergillus terreus NIH2624
BGC0000632.1 |  | 0.21 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001302.1 |  | 0.58 | Other | lomofungin | Streptomyces lomondensis
BGC0000454.1 |  | 0.55 | NRP | vanchrobactin | Vibrio anguillarum RV22
BGC0001343.1 |  | 0.55 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001641.1 |  | 0.54 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000349.1 |  | 0.54 | NRP | erythrochelin | Saccharopolyspora erythraea NRRL 2338
BGC0000401.1 |  | 0.54 | NRP | paenibactin | Paenibacillus elgii B69
BGC0001833.1 |  | 0.54 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.54 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001517.1 |  | 0.54 | NRP | asperphenamate | Aspergillus terreus NIH2624
BGC0000632.1 |  | 0.54 | Terpene, Saccharide | brasilicardin A | Nocardia terpenica

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP040991.1 - Region 1 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 555,515 - 565,907 nt. (total: 10,393 nt) Show pHMM detection rules used
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.53 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  | 0.53 | Other | ectoine | Methylophaga thalassica
BGC0000857.1 |  | 0.44 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.43 | Other | ectoine | Methylomicrobium kenyense
BGC0000860.1 |  | 0.43 | Other | ectoine | Methylarcula marina
BGC0000853.1 |  | 0.40 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.39 | Other | ectoine | Sporosarcina pasteurii
BGC0000854.1 |  | 0.39 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000858.1 |  | 0.32 | Other | ectoine | Methylobacter marinus
BGC0000919.1 |  | 0.14 | Other | phaseolotoxin | Pseudomonas syringae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.80 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  | 0.80 | Other | ectoine | Methylophaga thalassica
BGC0000857.1 |  | 0.74 | Other | ectoine | Methylophaga alcalica
BGC0000855.1 |  | 0.74 | Other | ectoine | Methylomicrobium kenyense
BGC0000860.1 |  | 0.74 | Other | ectoine | Methylarcula marina
BGC0000853.1 |  | 0.72 | Other | ectoine | Streptomyces anulatus
BGC0000852.1 |  | 0.71 | Other | ectoine | Sporosarcina pasteurii
BGC0000854.1 |  | 0.71 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000858.1 |  | 0.65 | Other | ectoine | Methylobacter marinus
BGC0000919.1 |  | 0.43 | Other | phaseolotoxin | Pseudomonas syringae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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NZ_CP040991.1 - Region 2 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
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Location: 1,218,339 - 1,238,920 nt. (total: 20,582 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.17 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000527.1 |  | 0.16 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000502.1 |  | 0.16 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000496.1 |  | 0.16 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000516.1 |  | 0.16 | RiPP | geobacillin II | Geobacillus thermodenitrificans
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001120.1 |  | 0.48 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000527.1 |  | 0.47 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000502.1 |  | 0.46 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000496.1 |  | 0.46 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000516.1 |  | 0.46 | RiPP | geobacillin II | Geobacillus thermodenitrificans
BGC0000504.1 |  | 0.46 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001210.1 |  | 0.46 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names