Select genomic region:
Overview
1.1
1.2
1.3
1.4
1.5
1.6
1.7
1.8

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP009125.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | hserlactone | 118,711 | 139,361 |
Region 1.2 | NRPS | 518,692 | 568,390 | amonabactin P 750 | NRP | 100%
Region 1.3 | T1PKS | 1,025,599 | 1,080,123 | oronofacic acid | Polyketide | 100%
Region 1.4 | NRPS | 1,643,949 | 1,727,659 | syringomycin | NRP | 17%
Region 1.5 | NRPS-like,phenazine | 2,038,870 | 2,080,654 | 1,6-phenazinedimethanol / fontizine A | NRP | 93%
Region 1.6 | betalactone | 4,141,136 | 4,164,955 |
Region 1.7 | siderophore | 4,489,118 | 4,501,019 |
Region 1.8 | arylpolyene | 4,940,574 | 4,984,202 | APE Ec | Other | 89%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | hserlactone | 118,711 | 139,361 |
Region 1.2 | NRPS | 518,692 | 568,390 | amonabactin P 750 | NRP | 100%
Region 1.3 | T1PKS | 1,025,599 | 1,080,123 | oronofacic acid | Polyketide | 100%
Region 1.4 | NRPS | 1,643,949 | 1,727,659 | syringomycin | NRP | 17%
Region 1.5 | NRPS-like,phenazine | 2,038,870 | 2,080,654 | 1,6-phenazinedimethanol / fontizine A | NRP | 93%
Region 1.6 | betalactone | 4,141,136 | 4,164,955 |
Region 1.7 | siderophore | 4,489,118 | 4,501,019 |
Region 1.8 | arylpolyene | 4,940,574 | 4,984,202 | APE Ec | Other | 89%

No secondary metabolite regions were found in these records:
  NZ_CP009126.1

Compact view
NZ_CP009125.1 - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 118,711 - 139,361 nt. (total: 20,651 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001525.1 |  | 0.16 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001788.1 |  | 0.16 | RiPP | suicin 65 | Streptococcus suis
BGC0000526.1 |  | 0.16 | RiPP | macedocin | Streptococcus macedonicus
BGC0000527.1 |  | 0.16 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000498.1 |  | 0.15 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.15 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000557.1 |  | 0.15 | RiPP | streptococcin A-FF22 | Streptococcus pyogenes
BGC0001787.1 |  | 0.15 | RiPP | suicin 3908 | Streptococcus suis
BGC0000547.1 |  | 0.15 | RiPP | salivaricin 9 | Streptococcus salivarius

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001525.1 |  | 0.46 | Other | bartoloside 2, bartoloside 3, bartoloside 4 | Synechocystis salina LEGE 06155
BGC0001526.1 |  | 0.46 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001788.1 |  | 0.46 | RiPP | suicin 65 | Streptococcus suis
BGC0000526.1 |  | 0.46 | RiPP | macedocin | Streptococcus macedonicus
BGC0000527.1 |  | 0.46 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0000498.1 |  | 0.46 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.46 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000557.1 |  | 0.46 | RiPP | streptococcin A-FF22 | Streptococcus pyogenes
BGC0001787.1 |  | 0.46 | RiPP | suicin 3908 | Streptococcus suis
BGC0000547.1 |  | 0.46 | RiPP | salivaricin 9 | Streptococcus salivarius

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP009125.1 - Region 2 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 518,692 - 568,390 nt. (total: 49,699 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001502.1 |  | 0.46 | NRP | amonabactin P 750 | Aeromonas hydrophila subsp. hydrophila ATCC 7966
BGC0000389.1 |  | 0.33 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.33 | NRP | sevadicin | Paenibacillus larvae
BGC0000465.1 |  | 0.33 | NRP | xenortide A, xenortide B, xenortide C, xenortide D | Xenorhabdus nematophila ATCC 19061
BGC0000457.1 |  | 0.30 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001050.1 |  | 0.28 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001825.1 |  | 0.27 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001185.1 |  | 0.26 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000317.1 |  | 0.26 | NRP | cephalosporin C | Acremonium chrysogenum ATCC 11550
BGC0000313.1 |  | 0.26 | NRP | beauvericin | Beauveria bassiana

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001502.1 |  | 0.76 | NRP | amonabactin P 750 | Aeromonas hydrophila subsp. hydrophila ATCC 7966
BGC0000389.1 |  | 0.66 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0000426.1 |  | 0.66 | NRP | sevadicin | Paenibacillus larvae
BGC0000465.1 |  | 0.66 | NRP | xenortide A, xenortide B, xenortide C, xenortide D | Xenorhabdus nematophila ATCC 19061
BGC0000457.1 |  | 0.64 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001050.1 |  | 0.62 | NRP, Polyketide | thalassospiramide A | Tistrella bauzanensis
BGC0001825.1 |  | 0.61 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001185.1 |  | 0.60 | NRP | bacillibactin | Bacillus velezensis FZB42
BGC0000317.1 |  | 0.60 | NRP | cephalosporin C | Acremonium chrysogenum ATCC 11550
BGC0000313.1 |  | 0.60 | NRP | beauvericin | Beauveria bassiana

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 2, location 518691 - 568390:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X) + (D-X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_466: dhb
  Search NORINE for peptide: strict or relaxed
  AMP-binding (30..438): dhb
  NRPSPredictor2: dhb
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      dhb, sal
    Small clusters prediction:
      dhb, sal
    Single AA prediction:
      dhb
  Stachelhaus prediction details:
    Stachelhaus sequence:
      PLPsQGVVNK
    Nearest Stachelhaus code:
      dhb
    Stachelhaus code match:
      90% (moderate)
ctg1_468: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (464..861): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAeDIGtVvK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      70% (weak)
ctg1_470: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (538..936): X
  NRPSPredictor2: hydrophobic-aliphatic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAmigGMVtK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      60% (weak)
ctg1_471: gly
  Search NORINE for peptide: strict or relaxed
  AMP-binding (221..613): gly
  NRPSPredictor2: gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      N/A
    Single AA prediction:
      gly
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGcIWK
    Nearest Stachelhaus code:
      gly
    Stachelhaus code match:
      90% (moderate)

NZ_CP009125.1 - Region 3 - T1PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,025,599 - 1,080,123 nt. (total: 54,525 nt) Show pHMM detection rules used
T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T1PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000041.1 |  | 0.48 | Polyketide | oronofacic acid | Pseudomonas syringae
BGC0001647.1 |  | 0.28 | Polyketide | lagunapyrone A, lagunapyrone B, lagunapyrone C | Streptomyces sp. MP131-18
BGC0001824.1 |  | 0.24 | NRP | xefoampeptides A-G | Xenorhabdus beddingii
BGC0000056.1 |  | 0.23 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001909.1 |  | 0.22 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001264.1 |  | 0.22 | Polyketide | betaenone A, betaenone B, betaenone C | Phoma betae
BGC0001280.1 |  | 0.22 | Polyketide | betaenone C, betaenone A | Phoma betae
BGC0000353.1 |  | 0.21 | NRP | tacrolimus | Streptomyces sp. MA6548
BGC0001793.1 |  | 0.21 | Polyketide | swainsonine | Chaetothyriaceae sp.
BGC0000122.1 |  | 0.21 | Polyketide | phenylnannolone A, phenylnannolone B, phenylnannolone C | Nannocystis pusilla

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000041.1 |  | 0.77 | Polyketide | oronofacic acid | Pseudomonas syringae
BGC0001647.1 |  | 0.62 | Polyketide | lagunapyrone A, lagunapyrone B, lagunapyrone C | Streptomyces sp. MP131-18
BGC0001824.1 |  | 0.57 | NRP | xefoampeptides A-G | Xenorhabdus beddingii
BGC0000056.1 |  | 0.56 | Polyketide | esperamicin | Actinomadura verrucosospora
BGC0001909.1 |  | 0.55 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0001264.1 |  | 0.55 | Polyketide | betaenone A, betaenone B, betaenone C | Phoma betae
BGC0001280.1 |  | 0.55 | Polyketide | betaenone C, betaenone A | Phoma betae
BGC0000353.1 |  | 0.54 | NRP | tacrolimus | Streptomyces sp. MA6548
BGC0001793.1 |  | 0.54 | Polyketide | swainsonine | Chaetothyriaceae sp.
BGC0000122.1 |  | 0.53 | Polyketide | phenylnannolone A, phenylnannolone B, phenylnannolone C | Nannocystis pusilla

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1025598 - 1080123:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (mxmal - redemal) + (ccmal)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_938: mal
  PKS_AT (585..886): mal
  ATSignature: Malonyl-CoA
  Top 3 matches:
    Malonyl-CoA: 95.8%
    inactive: 70.8%
    Methylmalonyl-CoA: 66.7%
  minowa: Malonyl-CoA
  Prediction, score:
    Malonyl-CoA: 197.6
    Methoxymalonyl-CoA: 95.6
    Methylmalonyl-CoA: 87.4
    inactive: 81.9
    Propionyl-CoA: 50.3
    Isobutyryl-CoA: 46.0
    Ethylmalonyl-CoA: 45.6
    2-Methylbutyryl-CoA: 32.9
    Acetyl-CoA: 29.4
    trans-1,2-CPDA: 25.9
    CHC-CoA: 20.8
    Benzoyl-CoA: 19.2
    fatty_acid: 14.0
    3-Methylbutyryl-CoA: 0.0
ctg1_939: mxmal - emal
  PKS_AT (93..387): mxmal
  ATSignature: 2-Methylbutyryl-CoA
  Top 3 matches:
    2-Methylbutyryl-CoA: 58.3%
    Isobutyryl-CoA: 54.2%
    Propionyl-CoA: 54.2%
  minowa: Methoxymalonyl-CoA
  Prediction, score:
    Methoxymalonyl-CoA: 86.6
    Methylmalonyl-CoA: 81.6
    2-Methylbutyryl-CoA: 78.4
    Ethylmalonyl-CoA: 64.3
    Propionyl-CoA: 61.4
    CHC-CoA: 58.2
    trans-1,2-CPDA: 43.1
    Isobutyryl-CoA: 35.6
    3-Methylbutyryl-CoA: 25.4
    Benzoyl-CoA: 23.5
    Acetyl-CoA: 17.4
    Malonyl-CoA: 14.7
    fatty_acid: 14.6
    inactive: 8.1
  PKS_AT (1102..1400): emal
  ATSignature: Ethylmalonyl-CoA
  Top 3 matches:
    Ethylmalonyl-CoA: 95.8%
    Methylmalonyl-CoA: 91.7%
    Methoxymalonyl-CoA: 87.5%
  minowa: Ethylmalonyl-CoA
  Prediction, score:
    Ethylmalonyl-CoA: 207.3
    Methylmalonyl-CoA: 175.1
    Methoxymalonyl-CoA: 142.0
    Malonyl-CoA: 106.3
    trans-1,2-CPDA: 104.9
    2-Methylbutyryl-CoA: 92.6
    Propionyl-CoA: 91.9
    CHC-CoA: 76.3
    Isobutyryl-CoA: 74.2
    Benzoyl-CoA: 56.3
    inactive: 34.3
    fatty_acid: 30.6
    Acetyl-CoA: 17.7
    3-Methylbutyryl-CoA: 13.8
ctg1_940: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (36..380): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      syAsTGtprK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      40% (weak)
ctg1_945: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (6..409): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      pwLaVGsGpK
    Nearest Stachelhaus code:
      tcl
    Stachelhaus code match:
      50% (weak)

NZ_CP009125.1 - Region 4 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,643,949 - 1,727,659 nt. (total: 83,711 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.49 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001758.1 |  | 0.37 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.36 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001844.1 |  | 0.36 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001641.1 |  | 0.35 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.1 |  | 0.35 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1 |  | 0.35 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.34 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001132.1 |  | 0.34 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000417.1 |  | 0.33 | NRP | rhodochelin | Rhodococcus jostii RHA1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.78 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001758.1 |  | 0.70 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001131.1 |  | 0.69 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001844.1 |  | 0.69 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001641.1 |  | 0.68 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001128.1 |  | 0.68 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1 |  | 0.68 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.67 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001132.1 |  | 0.67 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0000417.1 |  | 0.66 | NRP | rhodochelin | Rhodococcus jostii RHA1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 4, location 1643948 - 1727659:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X - asn - ser - val - gln - ser - gly) + (thr - tyr - ser - X - X - ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1449: thr - tyr - ser - X - X - ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (510..915): thr
  NRPSPredictor2: thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      thr
    Single AA prediction:
      thr
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code:
      thr
    Stachelhaus code match:
      100% (strong)
  AMP-binding (1597..1994): tyr
  NRPSPredictor2: tyr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      phe, trp, phg, tyr, bht
    Small clusters prediction:
      tyr, bht
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DASTIAAVCK
    Nearest Stachelhaus code:
      tyr
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2675..3073): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (3752..4147): X
  NRPSPredictor2: hydrophobic-aromatic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVqLVGaVcK
    Nearest Stachelhaus code:
      trp
    Stachelhaus code match:
      70% (weak)
  AMP-binding (4826..5229): X
  NRPSPredictor2: val, leu, ile, abu, iva
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DSaLiAEVwK
    Nearest Stachelhaus code:
      his
    Stachelhaus code match:
      70% (weak)
  AMP-binding (5914..6312): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
ctg1_1450: X - asn - ser - val - gln - ser - gly
  Search NORINE for peptide: strict or relaxed
  AMP-binding (487..885): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAvDLGVVDK
    Nearest Stachelhaus code:
      gln
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (1564..1965): asn
  NRPSPredictor2: asn
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asn
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DATKVGEVGK
    Nearest Stachelhaus code:
      asn
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2626..3024): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (3704..4100): val
  NRPSPredictor2: val
  SVM prediction details:
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAfLIGAVcK
    Nearest Stachelhaus code:
      val
    Stachelhaus code match:
      80% (moderate)
  AMP-binding (4779..5175): gln
  NRPSPredictor2: gln
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAvDLGVVDK
    Nearest Stachelhaus code:
      gln
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (5835..6233): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHISLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)
  AMP-binding (6912..7309): gly
  NRPSPredictor2: gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      gly
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLIWK
    Nearest Stachelhaus code:
      gly
    Stachelhaus code match:
      100% (strong)

NZ_CP009125.1 - Region 5 - NRPS-like,phenazine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,038,870 - 2,080,654 nt. (total: 41,785 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))
phenazine: phzB

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | phenazine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0002002.1 |  |  | 1.03 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola
BGC0001527.1 |  |  | 0.56 | Other | basidioferrin | Gelatoporia subvermispora
BGC0000328.1 |  |  | 0.49 | NRP | coronatine | Pseudomonas savastanoi pv. glycinea
BGC0001868.1 |  |  | 0.49 | Other (Phenazine) | iodinin | Xenorhabdus szentirmaii DSM 16338
BGC0000936.1 |  |  | 0.48 | Other | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0000662.1 |  |  | 0.43 | Terpene | grixazone | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001627.1 |  |  | 0.42 | NRP | isonitrile lipopeptides | Mycobacterium tuberculosis H37Rv
BGC0000427.1 |  |  | 0.42 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0000375.1 |  |  | 0.38 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001365.1 |  |  | 0.38 | NRP | clapurines | Claviceps purpurea 20.1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002002.1 |  | 0.81 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola
BGC0001527.1 |  | 0.62 | Other | basidioferrin | Gelatoporia subvermispora
BGC0001868.1 |  | 0.59 | Other (Phenazine) | iodinin | Xenorhabdus szentirmaii DSM 16338
BGC0000662.1 |  | 0.59 | Terpene | grixazone | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000328.1 |  | 0.58 | NRP | coronatine | Pseudomonas savastanoi pv. glycinea
BGC0000936.1 |  | 0.57 | Other | pyocyanine | Pseudomonas aeruginosa PAO1
BGC0001343.1 |  | 0.56 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0000938.1 |  | 0.55 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0001591.1 |  | 0.55 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.55 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 5, location 2038869 - 2080654:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (gly)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg1_1781: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (62..303): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      pro, pip
    Small clusters prediction:
      pro
    Single AA prediction:
      pro
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DvkI---LkK
    Nearest Stachelhaus code:
      lys-b
    Stachelhaus code match:
      40% (weak)
ctg1_1783: pk
  PKS_AT (17..119): pk
  ATSignature: (unknown)
  No matches above 50%
  minowa: trans-1,2-CPDA
  Prediction, score:
    trans-1,2-CPDA: 0.0
    inactive: 0.0
    fatty_acid: 0.0
    Propionyl-CoA: 0.0
    Methylmalonyl-CoA: 0.0
    Methoxymalonyl-CoA: 0.0
    Malonyl-CoA: 0.0
    Isobutyryl-CoA: 0.0
    Ethylmalonyl-CoA: 0.0
    CHC-CoA: 0.0
    Benzoyl-CoA: 0.0
    Acetyl-CoA: 0.0
    3-Methylbutyryl-CoA: 0.0
    2-Methylbutyryl-CoA: 0.0
ctg1_1784: gly
  Search NORINE for peptide: strict or relaxed
  AMP-binding (32..407): gly
  NRPSPredictor2: gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      gly
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLIWK
    Nearest Stachelhaus code:
      gly
    Stachelhaus code match:
      100% (strong)

NZ_CP009125.1 - Region 6 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,141,136 - 4,164,955 nt. (total: 23,820 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.16 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.16 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.13 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000597.1 |  | 0.13 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0001464.1 |  | 0.13 | Other | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.1 |  | 0.13 | Other | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0001411.1 |  | 0.13 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0000122.1 |  | 0.12 | Polyketide | phenylnannolone A, phenylnannolone B, phenylnannolone C | Nannocystis pusilla
BGC0001806.1 |  | 0.12 | NRP | tolaasin A | Pseudomonas tolaasii
BGC0000871.1 |  | 0.09 | Other (Nucleoside) | VEPE, AEPE, TG-1 | Myxococcus xanthus DK 1622

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.47 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000904.1 |  | 0.46 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001441.1 |  | 0.42 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000597.1 |  | 0.41 | RiPP | SWA-2138 | Streptomyces sp. e14
BGC0001464.1 |  | 0.41 | Other | tetrabromopyrrole | Pseudoalteromonas sp. PS5
BGC0001463.1 |  | 0.41 | Other | 2,3,4,5-tetrabromopyrrole | Pseudoalteromonas piscicida
BGC0001411.1 |  | 0.41 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0000122.1 |  | 0.40 | Polyketide | phenylnannolone A, phenylnannolone B, phenylnannolone C | Nannocystis pusilla
BGC0001806.1 |  | 0.39 | NRP | tolaasin A | Pseudomonas tolaasii
BGC0000871.1 |  | 0.34 | Other (Nucleoside) | VEPE, AEPE, TG-1 | Myxococcus xanthus DK 1622

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP009125.1 - Region 7 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,489,118 - 4,501,019 nt. (total: 11,902 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001685.1 |  | 0.21 | Other | N-acyloxyacyl lysine | Raoultella ornithinolytica 10-5246
BGC0001587.1 |  | 0.16 | Other | ethylenediaminesuccinic acid hydroxyarginine (EDHA) | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000294.1 |  | 0.15 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001684.1 |  | 0.14 | Other | N-acyloxyacyl glutamine | Klebsiella variicola
BGC0000896.1 |  | 0.14 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0001681.1 |  | 0.14 | Other | N-acyl glycine | Bacteroides fragilis 638R
BGC0000943.1 |  | 0.13 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000352.1 |  | 0.08 | NRP | fimsbactin A | Acinetobacter sp. ADP1
BGC0000469.1 |  | 0.07 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0001671.1 |  | 0.06 | NRP | monobactam | Agrobacterium tumefaciens

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001685.1 |  | 0.54 | Other | N-acyloxyacyl lysine | Raoultella ornithinolytica 10-5246
BGC0001587.1 |  | 0.47 | Other | ethylenediaminesuccinic acid hydroxyarginine (EDHA) | Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000294.1 |  | 0.46 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001684.1 |  | 0.44 | Other | N-acyloxyacyl glutamine | Klebsiella variicola
BGC0000896.1 |  | 0.43 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0001681.1 |  | 0.43 | Other | N-acyl glycine | Bacteroides fragilis 638R
BGC0000943.1 |  | 0.42 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000352.1 |  | 0.32 | NRP | fimsbactin A | Acinetobacter sp. ADP1
BGC0000469.1 |  | 0.29 | RiPP | bottromycin A2 | Streptomyces sp. BC16019
BGC0001671.1 |  | 0.27 | NRP | monobactam | Agrobacterium tumefaciens

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP009125.1 - Region 8 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,940,574 - 4,984,202 nt. (total: 43,629 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.50 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.46 | Other | APE Ec | Escherichia coli CFT073
BGC0000837.1 |  | 0.31 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0001591.1 |  | 0.22 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.22 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001897.1 |  | 0.22 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000873.1 |  | 0.21 | Other | A-201A | Saccharothrix mutabilis subsp. capreolus
BGC0000343.1 |  | 0.21 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000237.1 |  | 0.21 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000248.1 |  | 0.21 | Polyketide | naphtocyclinone | Streptomyces arenae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002008.1 |  | 0.79 | Other | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.1 |  | 0.76 | Other | APE Ec | Escherichia coli CFT073
BGC0000837.1 |  | 0.65 | Other | APE Vf | Aliivibrio fischeri ES114
BGC0001591.1 |  | 0.55 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.55 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0001897.1 |  | 0.54 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000873.1 |  | 0.54 | Other | A-201A | Saccharothrix mutabilis subsp. capreolus
BGC0000343.1 |  | 0.54 | NRP | enterobactin | Pseudomonas sp. J465
BGC0000237.1 |  | 0.54 | Polyketide | lactonamycin Z | Streptomyces sanglieri
BGC0000248.1 |  | 0.54 | Polyketide | naphtocyclinone | Streptomyces arenae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
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Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
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