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Overview
1.1
1.2

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP046314.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | sactipeptide | 304,131 | 329,631 |
Region 2 | T3PKS | 759,222 | 800,394 |

NZ_CP046314.1 - Region 1 - sactipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 304,131 - 329,631 nt. (total: 25,501 nt) Show pHMM detection rules used
sactipeptide: (subtilosin or thuricin or TIGR04404 or Subtilosin_A or skfc)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Sactipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | sactipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000602.1 |  | 0.17 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000601.1 |  | 0.16 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000522.1 |  | 0.16 | RiPP | lacticin Z | Lactococcus lactis
BGC0000620.1 |  | 0.15 | RiPP | lacticin Q | Lactococcus lactis
BGC0000703.1 |  | 0.13 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001540.1 |  | 0.13 | Other | CC-1065 | Streptomyces zelensis
BGC0001171.1 |  | 0.10 | RiPP | listeriolysin S | Listeria monocytogenes serotype 4b str. F2365
BGC0001618.1 |  | 0.09 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000555.1 |  | 0.08 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000556.1 |  | 0.08 | RiPP | streptin | Streptococcus pyogenes

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000602.1 |  | 0.48 | RiPP | subtilosin A | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0000601.1 |  | 0.47 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000522.1 |  | 0.46 | RiPP | lacticin Z | Lactococcus lactis
BGC0000620.1 |  | 0.46 | RiPP | lacticin Q | Lactococcus lactis
BGC0000703.1 |  | 0.41 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0001540.1 |  | 0.41 | Other | CC-1065 | Streptomyces zelensis
BGC0001171.1 |  | 0.36 | RiPP | listeriolysin S | Listeria monocytogenes serotype 4b str. F2365
BGC0001618.1 |  | 0.32 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000555.1 |  | 0.32 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000556.1 |  | 0.30 | RiPP | streptin | Streptococcus pyogenes

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Sactipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Sactipeptides - No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Sactipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists its RODEO score and predicted core sequence.
No core peptides found.
NZ_CP046314.1 - Region 2 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 759,222 - 800,394 nt. (total: 41,173 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000796.1 |  | 0.24 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0000286.1 |  | 0.23 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000719.1 |  | 0.22 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000720.1 |  | 0.20 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000867.1 |  | 0.20 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.20 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001120.1 |  | 0.18 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000724.1 |  | 0.18 | Saccharide | streptomycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000702.1 |  | 0.18 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000713.1 |  | 0.17 | Saccharide | ribostamycin | Streptomyces ribosidificus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000796.1 |  | 0.57 | Saccharide | S-layer glycan | Paenibacillus alvei
BGC0000286.1 |  | 0.56 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000719.1 |  | 0.54 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000720.1 |  | 0.53 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000867.1 |  | 0.52 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.52 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001120.1 |  | 0.50 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000724.1 |  | 0.49 | Saccharide | streptomycin | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000702.1 |  | 0.49 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000713.1 |  | 0.49 | Saccharide | ribostamycin | Streptomyces ribosidificus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names