GCF_025272815.1_ASM2527281v1_genomic - 6 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP102089.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	lanthipeptide-class-v	77,618	119,468
Region 1.2	NRPS	126,471	173,637
Region 1.3	terpene,T3PKS	391,303	442,691
Region 1.4	siderophore	749,098	764,077	staphyloferrin A	Other:Non-NRP siderophore	100%
Region 1.5	cyclic-lactone-autoinducer	891,230	911,939	kijanimicin	Polyketide	4%
Region 1.6	lanthipeptide-class-i	1,818,504	1,842,722	gallidermin	RiPP:Lanthipeptide	36%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	lanthipeptide-class-v	77,618	119,468
Region 1.2	NRPS	126,471	173,637
Region 1.3	terpene,T3PKS	391,303	442,691
Region 1.4	siderophore	749,098	764,077	staphyloferrin A	Other:Non-NRP siderophore	100%
Region 1.5	cyclic-lactone-autoinducer	891,230	911,939	kijanimicin	Polyketide	4%
Region 1.6	lanthipeptide-class-i	1,818,504	1,842,722	gallidermin	RiPP:Lanthipeptide	36%

No secondary metabolite regions were found in these records:: NZ_CP102090.1

Compact view

NZ_CP102089.1 - Region 1 - lanthipeptide-class-v

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Location: 77,618 - 119,468 nt. (total: 41,851 nt) Show pHMM detection rules used

lanthipeptide-class-v: (APH and HopA1)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000758.1	0.38	Saccharide	capsular polysaccharide	Staphylococcus aureus
BGC0001526.1	0.22	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.20	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000829.1	0.17	Alkaloid	violacein	Chromobacterium violaceum
BGC0001639.1	0.17	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000500.1	0.16	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000545.1	0.16	RiPP	ruminococcin A	[Ruminococcus] gnavus E1
BGC0000543.1	0.16	RiPP	pep5	Staphylococcus epidermidis
BGC0001391.1	0.16	RiPP	thusin	Bacillus thuringiensis serovar rongseni
BGC0000509.1	0.16	RiPP	epilancin 15x	Staphylococcus epidermidis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000758.1	0.71	Saccharide	capsular polysaccharide	Staphylococcus aureus
BGC0001526.1	0.55	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0001525.1	0.53	Other	bartoloside 2, bartoloside 3, bartoloside 4	Synechocystis salina LEGE 06155
BGC0000829.1	0.49	Alkaloid	violacein	Chromobacterium violaceum
BGC0001639.1	0.48	RiPP	klebsidin	Klebsiella pneumoniae
BGC0000500.1	0.47	RiPP	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0000545.1	0.47	RiPP	ruminococcin A	[Ruminococcus] gnavus E1
BGC0000543.1	0.47	RiPP	pep5	Staphylococcus epidermidis
BGC0001391.1	0.47	RiPP	thusin	Bacillus thuringiensis serovar rongseni
BGC0000509.1	0.47	RiPP	epilancin 15x	Staphylococcus epidermidis

Similar known gene clusters

No matches found.

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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Lanthipeptides

Core peptide predictions

No core peptides found.

NZ_CP102089.1 - Region 2 - NRPS

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Location: 126,471 - 173,637 nt. (total: 47,167 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000308.1	0.51	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001479.1	0.27	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001686.1	0.24	NRP	N-octanoyl-Met-Phe-H	Clostridium sp. CAG:567
BGC0001132.1	0.24	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.1	0.23	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000327.1	0.23	NRP	netropsin	Streptomyces ambofaciens ATCC 23877
BGC0001768.1	0.23	NRP	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001135.1	0.22	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001641.1	0.22	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.22	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000308.1	0.79	NRP	aureusimine	Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001479.1	0.61	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001686.1	0.58	NRP	N-octanoyl-Met-Phe-H	Clostridium sp. CAG:567
BGC0001132.1	0.57	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.1	0.56	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000327.1	0.56	NRP	netropsin	Streptomyces ambofaciens ATCC 23877
BGC0001768.1	0.56	NRP	sansalvamide	[Nectria] haematococca mpVI 77-13-4
BGC0001135.1	0.55	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001641.1	0.55	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.55	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 126470 - 173637:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (val - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_119

Search NORINE for peptide: strict or relaxed

AMP-binding (423..814): val

NRPSPredictor2: val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: val

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWlGGTFK
Nearest Stachelhaus code:: val
Stachelhaus code match:: 90% (moderate)

AMP-binding (1447..1830): X

NRPSPredictor2: hydrophobic-aliphatic

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAmSIGaViK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 70% (weak)

NZ_CP102089.1 - Region 3 - T3PKS,terpene

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Location: 391,303 - 442,691 nt. (total: 51,389 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000644.1	0.41	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000635.1	0.40	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000645.1	0.39	Terpene	carotenoid	Halobacillus halophilus DSM 2266
BGC0000637.1	0.38	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000648.1	0.37	Terpene	carotenoid	Myxococcus xanthus
BGC0000636.1	0.33	Terpene	carotenoid	Brevibacterium linens
BGC0000640.1	0.32	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000646.1	0.32	Terpene	β-carotein	uncultured bacterium
BGC0000806.1	0.32	Saccharide	phosphonoglycans	Glycomyces sp. NRRL B-16210
BGC0000641.1	0.31	Terpene	carotenoid	Enterobacteriaceae bacterium DC416

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.64	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000635.1	0.59	Terpene	carotenoid	Paracoccus sp. N81106
BGC0000644.1	0.59	Terpene	carotenoid	Dietzia sp. CQ4
BGC0000643.1	0.58	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000634.1	0.57	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000656.1	0.57	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000640.1	0.57	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000633.1	0.56	Terpene	carotenoid	Streptomyces avermitilis
BGC0000630.1	0.56	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000637.1	0.56	Terpene	carotenoid	Corynebacterium glutamicum

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_CP102089.1 - Region 4 - siderophore

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Location: 749,098 - 764,077 nt. (total: 14,980 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000944.1	0.57	Other (Non-NRP siderophore)	staphyloferrin A	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000939.1	0.22	Other	aerobactin	Grimontia hollisae
BGC0001870.1	0.22	Other	putrebactin, avaroferrin	Xenorhabdus budapestensis
BGC0000947.1	0.19	Other	vibrioferrin	Vibrio alginolyticus
BGC0000883.1	0.16	Other	arginomycin	Streptomyces arginensis
BGC0000943.1	0.15	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001767.1	0.09	NRP	salinichelins	Salinispora pacifica CNY331
BGC0000423.1	0.09	NRP	scabichelin	Streptomyces scabiei 87.22
BGC0000708.1	0.08	Saccharide	lividomycin	Streptomyces lividus
BGC0001211.1	0.08	NRP	albachelin	Amycolatopsis alba DSM 44262

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000944.1	0.83	Other (Non-NRP siderophore)	staphyloferrin A	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000939.1	0.55	Other	aerobactin	Grimontia hollisae
BGC0001870.1	0.54	Other	putrebactin, avaroferrin	Xenorhabdus budapestensis
BGC0000947.1	0.51	Other	vibrioferrin	Vibrio alginolyticus
BGC0000883.1	0.47	Other	arginomycin	Streptomyces arginensis
BGC0000943.1	0.46	Other	staphylobactin	Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001767.1	0.34	NRP	salinichelins	Salinispora pacifica CNY331
BGC0000423.1	0.33	NRP	scabichelin	Streptomyces scabiei 87.22
BGC0000708.1	0.32	Saccharide	lividomycin	Streptomyces lividus
BGC0001211.1	0.32	NRP	albachelin	Amycolatopsis alba DSM 44262

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP102089.1 - Region 5 - cyclic-lactone-autoinducer

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Location: 891,230 - 911,939 nt. (total: 20,710 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001687.1	0.13	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12
BGC0000207.1	0.13	Polyketide	chartreusin	Streptomyces chartreusis
BGC0000540.1	0.12	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0001053.1	0.08	NRP, Polyketide	tubulysin A	Archangium disciforme
BGC0000082.1	0.06	Polyketide	kijanimicin	Actinomadura kijaniata
BGC0001056.1	0.05	NRP, Polyketide	zeamine, zeamine I, zeamine II, prezeamine, prezeamine I	Serratia plymuthica RVH1
BGC0001700.1	0.05	Polyketide	niphimycins C-E	Streptomyces sp. IMB7-145
BGC0000163.1	0.03	Polyketide	tetronasin	Streptomyces longisporoflavus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001687.1	0.42	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12
BGC0000207.1	0.41	Polyketide	chartreusin	Streptomyces chartreusis
BGC0000540.1	0.40	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF
BGC0001053.1	0.30	NRP, Polyketide	tubulysin A	Archangium disciforme
BGC0000082.1	0.24	Polyketide	kijanimicin	Actinomadura kijaniata
BGC0001056.1	0.24	NRP, Polyketide	zeamine, zeamine I, zeamine II, prezeamine, prezeamine I	Serratia plymuthica RVH1
BGC0001700.1	0.21	Polyketide	niphimycins C-E	Streptomyces sp. IMB7-145
BGC0000163.1	0.17	Polyketide	tetronasin	Streptomyces longisporoflavus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NZ_CP102089.1 - Region 6 - lanthipeptide-class-i

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Location: 1,818,504 - 1,842,722 nt. (total: 24,219 nt) Show pHMM detection rules used

lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Lanthipeptides

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000508.1	0.24	RiPP	epidermin	Staphylococcus epidermidis
BGC0001289.1	0.22	RiPP	penisin	Paenibacillus ehimensis
BGC0000543.1	0.22	RiPP	pep5	Staphylococcus epidermidis
BGC0000560.1	0.22	RiPP	subtilomycin	Bacillus subtilis
BGC0000538.1	0.21	RiPP	nisin Z	Lactococcus lactis
BGC0001618.1	0.21	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0000514.1	0.20	RiPP	gallidermin	Staphylococcus gallinarum
BGC0000531.1	0.20	RiPP	mutacin I	Streptococcus mutans
BGC0000509.1	0.20	RiPP	epilancin 15x	Staphylococcus epidermidis
BGC0000540.1	0.19	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000508.1	0.57	RiPP	epidermin	Staphylococcus epidermidis
BGC0001289.1	0.55	RiPP	penisin	Paenibacillus ehimensis
BGC0000543.1	0.55	RiPP	pep5	Staphylococcus epidermidis
BGC0000560.1	0.55	RiPP	subtilomycin	Bacillus subtilis
BGC0000538.1	0.54	RiPP	nisin Z	Lactococcus lactis
BGC0001618.1	0.53	RiPP	hyicin 3682	Staphylococcus hyicus
BGC0000514.1	0.53	RiPP	gallidermin	Staphylococcus gallinarum
BGC0000531.1	0.52	RiPP	mutacin I	Streptococcus mutans
BGC0000509.1	0.52	RiPP	epilancin 15x	Staphylococcus epidermidis
BGC0000540.1	0.51	RiPP	paenibacillin	Paenibacillus polymyxa OSY-DF

Similar known gene clusters

Lanthipeptide predictions

Lanthipeptides - No core peptides found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

Lanthipeptides

Core peptide predictions

No core peptides found.