Select genomic region:
Overview
5.1
5.2
5.3
5.4
5.5
5.6
5.7

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_UGZE01000001 (original name was: NZ_UGZE01000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | terpene | 96,529 | 117,299 |
Region 5.2 | siderophore | 186,212 | 201,465 | staphylobactin | Other | 68%
Region 5.3 | T3PKS | 440,107 | 481,276 | capsular polysaccharide | Saccharide:Exopolysaccharide | 3%
Region 5.4 | siderophore | 776,908 | 790,965 | staphyloferrin A | Other:Non-NRP siderophore | 75%
Region 5.5 | cyclic-lactone-autoinducer | 913,895 | 934,604 |
Region 5.6 | terpene | 1,269,567 | 1,290,391 |
Region 5.7 | NRPS | 2,582,464 | 2,633,023 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 5.1 | terpene | 96,529 | 117,299 |
Region 5.2 | siderophore | 186,212 | 201,465 | staphylobactin | Other | 68%
Region 5.3 | T3PKS | 440,107 | 481,276 | capsular polysaccharide | Saccharide:Exopolysaccharide | 3%
Region 5.4 | siderophore | 776,908 | 790,965 | staphyloferrin A | Other:Non-NRP siderophore | 75%
Region 5.5 | cyclic-lactone-autoinducer | 913,895 | 934,604 |
Region 5.6 | terpene | 1,269,567 | 1,290,391 |
Region 5.7 | NRPS | 2,582,464 | 2,633,023 |

No secondary metabolite regions were found in these records:
  NZ_UGZE01000004 (original name was: NZ_UGZE01000004.1)
  NZ_UGZE01000005 (original name was: NZ_UGZE01000005.1)
  NZ_UGZE01000003 (original name was: NZ_UGZE01000003.1)
  NZ_UGZE01000002 (original name was: NZ_UGZE01000002.1)

Compact view
c00005_NZ_UGZE.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 96,529 - 117,299 nt. (total: 20,771 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.32 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.21 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001227.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001456.1 |  | 0.21 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000636.1 |  | 0.20 | Terpene | carotenoid | Brevibacterium linens
BGC0000633.1 |  | 0.20 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.20 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000646.1 |  | 0.19 | Terpene | β-carotein | uncultured bacterium
BGC0001200.1 |  | 0.06 | Polyketide | lorneic acid A | Streptomyces sp. NBRC 109706

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.65 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.56 | Terpene | carotenoid | Myxococcus xanthus
BGC0000645.1 |  | 0.54 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001227.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0001456.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000636.1 |  | 0.52 | Terpene | carotenoid | Brevibacterium linens
BGC0000633.1 |  | 0.52 | Terpene | carotenoid | Streptomyces avermitilis
BGC0000664.1 |  | 0.52 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000646.1 |  | 0.52 | Terpene | β-carotein | uncultured bacterium
BGC0001200.1 |  | 0.25 | Polyketide | lorneic acid A | Streptomyces sp. NBRC 109706

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 186,212 - 201,465 nt. (total: 15,254 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000943.1 |  | 0.44 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000946.1 |  | 0.36 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000295.1 |  | 0.32 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.1 |  | 0.29 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000942.1 |  | 0.23 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001408.1 |  | 0.18 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000947.1 |  | 0.16 | Other | vibrioferrin | Vibrio alginolyticus
BGC0000294.1 |  | 0.15 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000896.1 |  | 0.14 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0001587.1 |  | 0.13 | Other | ethylenediaminesuccinic acid hydroxyarginine (EDHA) | Streptomyces avermitilis MA-4680 = NBRC 14893

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000943.1 |  | 0.75 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000946.1 |  | 0.69 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000295.1 |  | 0.65 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.1 |  | 0.63 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000942.1 |  | 0.56 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001408.1 |  | 0.49 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0000947.1 |  | 0.46 | Other | vibrioferrin | Vibrio alginolyticus
BGC0000294.1 |  | 0.45 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000896.1 |  | 0.43 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0001587.1 |  | 0.42 | Other | ethylenediaminesuccinic acid hydroxyarginine (EDHA) | Streptomyces avermitilis MA-4680 = NBRC 14893

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 3 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 440,107 - 481,276 nt. (total: 41,170 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.23 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000867.1 |  | 0.17 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.17 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001739.1 |  | 0.16 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001104.1 |  | 0.16 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0001335.1 |  | 0.16 | Alkaloid | borregomycin A, borregomycin B, borregomycin C, borregomycin D | uncultured bacterium
BGC0000934.1 |  | 0.16 | Other (Phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0000205.1 |  | 0.16 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001538.1 |  | 0.15 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000922.1 |  | 0.15 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.56 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000867.1 |  | 0.48 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0000866.1 |  | 0.48 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0001739.1 |  | 0.47 | Other | phosphonoacetic Acid | Streptomyces sp. NRRL F-525
BGC0001104.1 |  | 0.47 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0001335.1 |  | 0.46 | Alkaloid | borregomycin A, borregomycin B, borregomycin C, borregomycin D | uncultured bacterium
BGC0000934.1 |  | 0.46 | Other (Phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0000205.1 |  | 0.46 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001538.1 |  | 0.46 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000922.1 |  | 0.46 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 4 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 776,908 - 790,965 nt. (total: 14,058 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.29 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000883.1 |  | 0.16 | Other | arginomycin | Streptomyces arginensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.62 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000883.1 |  | 0.46 | Other | arginomycin | Streptomyces arginensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 5 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 913,895 - 934,604 nt. (total: 20,710 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.1 |  | 0.18 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0001687.1 |  | 0.13 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0000207.1 |  | 0.13 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000540.1 |  | 0.12 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001872.1 |  | 0.08 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0001053.1 |  | 0.08 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001836.1 |  | 0.07 | Polyketide | tartrolon D, tartrolon F, tartrolon G | Gynuella sunshinyii YC6258
BGC0001130.1 |  | 0.07 | NRP, Polyketide | fabclavine Ia | Xenorhabdus budapestensis
BGC0001056.1 |  | 0.05 | NRP, Polyketide | zeamine, zeamine I, zeamine II, prezeamine, prezeamine I | Serratia plymuthica RVH1
BGC0000082.1 |  | 0.04 | Polyketide | kijanimicin | Actinomadura kijaniata

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.1 |  | 0.49 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0001687.1 |  | 0.42 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0000207.1 |  | 0.42 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0000540.1 |  | 0.40 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001872.1 |  | 0.31 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0001053.1 |  | 0.30 | NRP, Polyketide | tubulysin A | Archangium disciforme
BGC0001836.1 |  | 0.28 | Polyketide | tartrolon D, tartrolon F, tartrolon G | Gynuella sunshinyii YC6258
BGC0001130.1 |  | 0.27 | NRP, Polyketide | fabclavine Ia | Xenorhabdus budapestensis
BGC0001056.1 |  | 0.24 | NRP, Polyketide | zeamine, zeamine I, zeamine II, prezeamine, prezeamine I | Serratia plymuthica RVH1
BGC0000082.1 |  | 0.20 | Polyketide | kijanimicin | Actinomadura kijaniata

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 6 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,269,567 - 1,290,391 nt. (total: 20,825 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001903.1 |  | 0.17 | Other | neocarazostatin A | Streptomyces sp. MA37
BGC0001150.1 |  | 0.15 | Polyketide | pamamycin-607 | Streptomyces alboniger
BGC0000922.1 |  | 0.14 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0001810.1 |  | 0.14 | Polyketide | trehangelin | Polymorphospora rubra
BGC0001080.1 |  | 0.12 | Other (Phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0000204.1 |  | 0.10 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0000914.1 |  | 0.09 | Other | methylenomycin A | Streptomyces coelicolor A3(2)
BGC0000261.1 |  | 0.09 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000225.1 |  | 0.07 | Polyketide | frenolicin B | Streptomyces roseofulvus
BGC0001829.1 |  | 0.07 | NRP, Polyketide | α,β-epoxyketone | Streptomyces chromofuscus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001903.1 |  | 0.49 | Other | neocarazostatin A | Streptomyces sp. MA37
BGC0001150.1 |  | 0.44 | Polyketide | pamamycin-607 | Streptomyces alboniger
BGC0000922.1 |  | 0.43 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0001810.1 |  | 0.43 | Polyketide | trehangelin | Polymorphospora rubra
BGC0001080.1 |  | 0.39 | Other (Phenazine) | endophenazine A, endophenazine B | Streptomyces anulatus
BGC0000204.1 |  | 0.36 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0000914.1 |  | 0.33 | Other | methylenomycin A | Streptomyces coelicolor A3(2)
BGC0000261.1 |  | 0.32 | Polyketide | R1128 | Streptomyces sp. R1128
BGC0000225.1 |  | 0.29 | Polyketide | frenolicin B | Streptomyces roseofulvus
BGC0001829.1 |  | 0.27 | NRP, Polyketide | α,β-epoxyketone | Streptomyces chromofuscus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00005_NZ_UGZE.. - Region 7 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,582,464 - 2,633,023 nt. (total: 50,560 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000308.1 |  | 0.37 | NRP | aureusimine | Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001686.1 |  | 0.27 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001261.1 |  | 0.27 | NRP | AM-toxin | Alternaria alternata
BGC0001825.1 |  | 0.27 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001132.1 |  | 0.27 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.26 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.26 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000342.1 |  | 0.26 | NRP | enniatin | Fusarium equiseti
BGC0000313.1 |  | 0.26 | NRP | beauvericin | Beauveria bassiana
BGC0001873.1 |  | 0.25 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000308.1 |  | 0.70 | NRP | aureusimine | Staphylococcus aureus subsp. aureus str. JKD6008
BGC0001686.1 |  | 0.61 | NRP | N-octanoyl-Met-Phe-H | Clostridium sp. CAG:567
BGC0001261.1 |  | 0.60 | NRP | AM-toxin | Alternaria alternata
BGC0001825.1 |  | 0.60 | NRP | xenematide | Xenorhabdus nematophila AN6/1
BGC0001132.1 |  | 0.60 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001833.1 |  | 0.60 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001135.1 |  | 0.59 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0000342.1 |  | 0.59 | NRP | enniatin | Fusarium equiseti
BGC0000313.1 |  | 0.59 | NRP | beauvericin | Beauveria bassiana
BGC0001873.1 |  | 0.59 | NRP | pyrrolizixenamide A | Xenorhabdus szentirmaii DSM 16338

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 7, location 2582463 - 2633023:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (ser - ser - ser)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg5_2485: ser - ser - ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (449..852): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHLSLIeK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (1487..1890): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHLSLIeK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (2525..2927): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHLtLIeK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      80% (moderate)