Select genomic region:
Overview
3.1
3.2
3.3
3.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_UFXF01000001 (original name was: NZ_UFXF01000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | cyclic-lactone-autoinducer | 1,349,798 | 1,368,413 |
Region 3.2 | cyclic-lactone-autoinducer | 2,469,980 | 2,489,971 |
Region 3.3 | ranthipeptide | 4,572,260 | 4,593,935 |
Region 3.4 | cyclic-lactone-autoinducer | 4,688,578 | 4,709,347 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | cyclic-lactone-autoinducer | 1,349,798 | 1,368,413 |
Region 3.2 | cyclic-lactone-autoinducer | 2,469,980 | 2,489,971 |
Region 3.3 | ranthipeptide | 4,572,260 | 4,593,935 |
Region 3.4 | cyclic-lactone-autoinducer | 4,688,578 | 4,709,347 |

No secondary metabolite regions were found in these records:
  NZ_UFXF01000003 (original name was: NZ_UFXF01000003.1)
  NZ_UFXF01000002 (original name was: NZ_UFXF01000002.1)

Compact view
c00003_NZ_UFXF.. - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,349,798 - 1,368,413 nt. (total: 18,616 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.25 | RiPP | circularin A | Clostridium beijerinckii
BGC0001521.1 |  | 0.20 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0000513.1 |  | 0.20 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0001839.1 |  | 0.19 | Terpene | squalestatin S1 | Aspergillus sp. Z5
BGC0000554.1 |  | 0.17 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001210.1 |  | 0.16 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000487.1 |  | 0.16 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.58 | RiPP | circularin A | Clostridium beijerinckii
BGC0001521.1 |  | 0.53 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0000513.1 |  | 0.52 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0001839.1 |  | 0.51 | Terpene | squalestatin S1 | Aspergillus sp. Z5
BGC0000554.1 |  | 0.48 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001526.1 |  | 0.47 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0001210.1 |  | 0.47 | RiPP | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0000487.1 |  | 0.47 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000616.1 |  | 0.47 | RiPP | amylocyclicin | Bacillus velezensis FZB42

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_UFXF.. - Region 2 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,469,980 - 2,489,971 nt. (total: 19,992 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000487.1 |  | 0.16 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000498.1 |  | 0.16 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.16 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000489.1 |  | 0.16 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000488.1 |  | 0.16 | RiPP | circularin A | Clostridium beijerinckii
BGC0000519.1 |  | 0.15 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000539.1 |  | 0.15 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000496.1 |  | 0.15 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000938.1 |  | 0.15 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000487.1 |  | 0.47 | RiPP | carnocyclin | Carnobacterium maltaromaticum
BGC0000498.1 |  | 0.47 | RiPP | bovicin HJ50 | Streptococcus equinus
BGC0000561.1 |  | 0.47 | RiPP | thermophilin 1277 | Streptococcus thermophilus
BGC0000504.1 |  | 0.46 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000489.1 |  | 0.46 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000488.1 |  | 0.46 | RiPP | circularin A | Clostridium beijerinckii
BGC0000519.1 |  | 0.46 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000539.1 |  | 0.45 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000496.1 |  | 0.45 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000938.1 |  | 0.45 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_UFXF.. - Region 3 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,572,260 - 4,593,935 nt. (total: 21,676 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000231.1 |  | 0.17 | Polyketide | griseusin | Streptomyces griseus
BGC0001987.1 |  | 0.15 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000207.1 |  | 0.15 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0001917.1 |  | 0.15 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000228.1 |  | 0.15 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0001605.1 |  | 0.15 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000698.1 |  | 0.14 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000010.1 |  | 0.14 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001810.1 |  | 0.14 | Polyketide | trehangelin | Polymorphospora rubra
BGC0001197.1 |  | 0.14 | Polyketide | frankiamicin | Frankia sp. EAN1pec

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000231.1 |  | 0.49 | Polyketide | griseusin | Streptomyces griseus
BGC0001987.1 |  | 0.46 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000207.1 |  | 0.46 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0001917.1 |  | 0.45 | Polyketide | 5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals | Streptomyces nigrescens
BGC0000228.1 |  | 0.45 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0001605.1 |  | 0.44 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0000698.1 |  | 0.44 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0000010.1 |  | 0.44 | Polyketide | aflatoxin | Aspergillus flavus
BGC0001810.1 |  | 0.44 | Polyketide | trehangelin | Polymorphospora rubra
BGC0001197.1 |  | 0.44 | Polyketide | frankiamicin | Frankia sp. EAN1pec

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00003_NZ_UFXF.. - Region 4 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 4,688,578 - 4,709,347 nt. (total: 20,770 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001410.1 |  | 0.23 | Saccharide | polysaccharide A | Bacteroides fragilis
BGC0000488.1 |  | 0.22 | RiPP | circularin A | Clostridium beijerinckii
BGC0001291.1 |  | 0.22 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0000767.1 |  | 0.21 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0000765.1 |  | 0.21 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0001441.1 |  | 0.21 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001586.1 |  | 0.19 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000938.1 |  | 0.18 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0001440.1 |  | 0.18 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea
BGC0000711.1 |  | 0.18 | Saccharide | neomycin | Streptomyces fradiae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001410.1 |  | 0.56 | Saccharide | polysaccharide A | Bacteroides fragilis
BGC0000488.1 |  | 0.55 | RiPP | circularin A | Clostridium beijerinckii
BGC0001291.1 |  | 0.55 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0000767.1 |  | 0.54 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0000765.1 |  | 0.54 | Saccharide | exopolysaccharide | Lactobacillus johnsonii
BGC0001441.1 |  | 0.54 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0001586.1 |  | 0.51 | Saccharide | EPS273 | Pseudomonas stutzeri
BGC0000938.1 |  | 0.50 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0001440.1 |  | 0.50 | Other | cystargolide A, cystargolide B | Kitasatospora cystarginea
BGC0000711.1 |  | 0.50 | Saccharide | neomycin | Streptomyces fradiae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names