LOCUS       c00030_NZ_JHYD..       20690 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHYD01000041.1 Ruminiclostridium cellobioparum DSM 1351 = ATCC
            15832 T344DRAFT_scaffold00030.30_C, whole genome shotgun sequence.
ACCESSION   NZ_JHYD01000041
VERSION     NZ_JHYD01000041
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:33:25
            Original ID  :: NZ_JHYD01000041.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 20690
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..105)
                     /locus_tag="ctg30_1"
                     /transl_table=11
                     /translation="MLCNWNSHVDYQKKLLLDLILFSEIEKSRVVSLEK"
     protocluster    1..20690
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2169:10690]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2170..10690
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..20690
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20690
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             355..1059
                     /locus_tag="ctg30_2"
                     /transl_table=11
                     /translation="MTRTELINELRKYRCADLSDAMDALGMVNVGSMNPNMKPLRPGME
                     FKGFAYTVKLLPKQTPNKQCKTVAEYKEELTRECENIYSFVNDITPENAKDMVVVIDME
                     GIVGGIWGSEIAMNMMIRGIEGAVIDGACRDSYETNLEKANVFCTQRTYNHVYGRARGG
                     ARNIPVHCAGVTVKPGDIICADDDGVLVIPYEVAEDVIKFARLQLEEDIATRSSHYEKL
                     GFEPDATLERNR"
     PFAM_domain     400..927
                     /aSDomain="RraA-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03737.17"
                     /description="Aldolase/RraA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_2_0001"
                     /evalue="8.00E-29"
                     /label="ctg30_2"
                     /locus_tag="ctg30_2"
                     /protein_end="191"
                     /protein_start="15"
                     /score="100.8"
                     /tool="antismash"
                     /translation="ADLSDAMDALGMVNVGSMNPNMKPLRPGMEFKGFAYTVKLLPKQT
                     PNKQCKTVAEYKEELTRECENIYSFVNDITPENAKDMVVVIDMEGIVGGIWGSEIAMNM
                     MIRGIEGAVIDGACRDSYETNLEKANVFCTQRTYNHVYGRARGGARNIPVHCAGVTVKP
                     GDIICADDDGVLV"
     CDS             1146..2180
                     /NRPS_PKS="Domain: PKS_ER (18-291). E-value: 2.2e-17.
                     Score: 55.0. Matches aSDomain:
                     nrpspksdomains_ctg30_3_PKS_ER.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 267.3; E-value:
                     2.7e-81)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_3"
                     /transl_table=11
                     /translation="MKAIQKTAGKPGAQFVELEIPRPGRNEVLVQVKAAALCRSDVDVY
                     EWTQLVQNAHYKLPFTMGHEFSGIVVEVGADVKGIRAGDRVAGETHIPCGCCNTCRTGN
                     QHICRNNMGVIGRSFDGCFAQYIKIPEIAAVKLPDSITYRQGALLEPFTTAMHALSKAN
                     PSGSSTAILGMGTIGLMAVELAKFLGSTKIFAMGNNELRLAESRRLGADVAINGSREDF
                     VQAIMRETNGVGVASIIDMTGNEDVINKSVEALKVAGTLVHVGMVPKPLTFNNYMYGVV
                     YKELNVTGIFGRRMFESWETVLSILSTGRIGLDNYIGKVTELENFEQAIADFRGVTGRI
                     IFEL"
     aSDomain        1200..2018
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_3_PKS_ER.1"
                     /evalue="2.20E-17"
                     /label="ctg30_3_PKS_ER.1"
                     /locus_tag="ctg30_3"
                     /protein_end="291"
                     /protein_start="18"
                     /score="55.0"
                     /tool="antismash"
                     /translation="EIPRPGRNEVLVQVKAAALCRSDVDVYEWTQLVQNAHYKLPFTMG
                     HEFSGIVVEVGADVKGIRAGDRVAGETHIPCGCCNTCRTGNQHICRNNMGVIGRSFDGC
                     FAQYIKIPEIAAVKLPDSITYRQGALLEPFTTAMHALSKANPSGSSTAILGMGTIGLMA
                     VELAKFLGSTKIFAMGNNELRLAESRRLGADVAINGSREDFVQAIMRETNGVGVASIID
                     MTGNEDVINKSVEALKVAGTLVHVGMVPKPLTFNNYMYGVVYKELNVTGIF"
     PFAM_domain     1221..1553
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08240.14"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_3_0002"
                     /evalue="7.30E-30"
                     /label="ctg30_3"
                     /locus_tag="ctg30_3"
                     /protein_end="136"
                     /protein_start="25"
                     /score="103.2"
                     /tool="antismash"
                     /translation="NEVLVQVKAAALCRSDVDVYEWTQLVQNAHYKLPFTMGHEFSGIV
                     VEVGADVKGIRAGDRVAGETHIPCGCCNTCRTGNQHICRNNMGVIGRSFDGCFAQYIKI
                     PEIAAVK"
     CDS_motif       1329..1367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg30_3_0001"
                     /evalue="2.90E-04"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg30_3"
                     /protein_end="74"
                     /protein_start="61"
                     /score="13.7"
                     /tool="antismash"
                     /translation="MGHEFSGIVVEVG"
     PFAM_domain     1674..2063
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00107.28"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_3_0003"
                     /evalue="1.30E-24"
                     /label="ctg30_3"
                     /locus_tag="ctg30_3"
                     /protein_end="306"
                     /protein_start="176"
                     /score="86.8"
                     /tool="antismash"
                     /translation="IGLMAVELAKFLGSTKIFAMGNNELRLAESRRLGADVAINGSRED
                     FVQAIMRETNGVGVASIIDMTGNEDVINKSVEALKVAGTLVHVGMVPKPLTFNNYMYGV
                     VYKELNVTGIFGRRMFESWETVLSIL"
     CDS_motif       1914..1940
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg30_3_0002"
                     /evalue="2.50E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg30_3"
                     /protein_end="265"
                     /protein_start="256"
                     /score="-1.2"
                     /tool="antismash"
                     /translation="VAGTLVHVG"
     CDS             2170..3090
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 201.4;
                     E-value: 4.6e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_4"
                     /sec_met_domain="HMGL-like (E-value: 2.6e-48, bitscore:
                     156.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSFNIEKEGVKMIANHNCKEVSIFEVGPRDGLQPEPVFIPTEKKI
                     ELVNRLTDAGCKRIEVTSFVHPRWVPQMADSKEVLAGIRKKEGVTYNALIPNLRGLELA
                     MECGLKEVVTIMSTSESHNKKNLNMSTGDSLKEIEQINKVAAKNGVKVRSYIATVFGCP
                     IEGEMSPKRALEIALKLEEYGSYEISLGDTTGMANPVSAYEIPKMINEKLTGAKLAVHY
                     HKYHGLEFANNLASFEAGIRIFDGAAGGLGGCPYAPGAKGNCQTEILVEMFHRMGIETG
                     IDLKQIYEAGEYAQTLSTLLHSRCV"
     PFAM_domain     2230..3048
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_4_0004"
                     /evalue="6.50E-46"
                     /label="ctg30_4"
                     /locus_tag="ctg30_4"
                     /protein_end="293"
                     /protein_start="20"
                     /score="157.1"
                     /tool="antismash"
                     /translation="VSIFEVGPRDGLQPEPVFIPTEKKIELVNRLTDAGCKRIEVTSFV
                     HPRWVPQMADSKEVLAGIRKKEGVTYNALIPNLRGLELAMECGLKEVVTIMSTSESHNK
                     KNLNMSTGDSLKEIEQINKVAAKNGVKVRSYIATVFGCPIEGEMSPKRALEIALKLEEY
                     GSYEISLGDTTGMANPVSAYEIPKMINEKLTGAKLAVHYHKYHGLEFANNLASFEAGIR
                     IFDGAAGGLGGCPYAPGAKGNCQTEILVEMFHRMGIETGIDLKQIYEAGEY"
     CDS             3289..4599
                     /locus_tag="ctg30_5"
                     /transl_table=11
                     /translation="MNAKLLDIKKKYISGDIKSQNLESAIFTQVYGADPENIREACNDA
                     AYVRCEAVEEATGASLDIIKNTRLDNCSLVGGDRILAGIEGKIGAATIPMGIAGPVKIN
                     GQFVDEKVYIPLATNEAALVAGVQRGIKAINMAGGLNTLVHFDGMTRAPLIEAPNIAEA
                     RRFCRQIVTDKVLFKELAVLSRDPFVRLEQIDPYQLGTKVFLRMTFKTGDAMGMNGVTK
                     ASADITRGILAKMPQWKLITISSNLCSDKKSSHINVLNGRGKSIQTEVFIPDEVLKAVF
                     KKGVNARSVEKTVFHKCYLGSCYSGTIAGFNVNAANAVAAFYAATGQDLAHVISSSSCF
                     VQADAAEGGVHFMVSLPCMELATIGGGTMFGTAKEALRLIGCGGFGKSVDDNVNVLRLA
                     EIAATAVTALELNTACAQAAGYEMADSHVKLARGEEA"
     PFAM_domain     3430..4584
                     /aSDomain="HMG-CoA_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00368.20"
                     /description="Hydroxymethylglutaryl-coenzyme A reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_5_0005"
                     /evalue="3.90E-84"
                     /label="ctg30_5"
                     /locus_tag="ctg30_5"
                     /protein_end="432"
                     /protein_start="47"
                     /score="282.9"
                     /tool="antismash"
                     /translation="VRCEAVEEATGASLDIIKNTRLDNCSLVGGDRILAGIEGKIGAAT
                     IPMGIAGPVKINGQFVDEKVYIPLATNEAALVAGVQRGIKAINMAGGLNTLVHFDGMTR
                     APLIEAPNIAEARRFCRQIVTDKVLFKELAVLSRDPFVRLEQIDPYQLGTKVFLRMTFK
                     TGDAMGMNGVTKASADITRGILAKMPQWKLITISSNLCSDKKSSHINVLNGRGKSIQTE
                     VFIPDEVLKAVFKKGVNARSVEKTVFHKCYLGSCYSGTIAGFNVNAANAVAAFYAATGQ
                     DLAHVISSSSCFVQADAAEGGVHFMVSLPCMELATIGGGTMFGTAKEALRLIGCGGFGK
                     SVDDNVNVLRLAEIAATAVTALELNTACAQAAGYEMADSHVKLAR"
     CDS             4704..5615
                     /locus_tag="ctg30_6"
                     /transl_table=11
                     /translation="MYESIKKYMKVGLIHFMAYPATMKGEGPIEETVKKIAADSYFDAI
                     ELTWIKDPQTRKNVRKMLDSSHMTVAYGGQPRLLTTGMNINDLDESKRMAAVANLKEGI
                     DEAYEMGASGFAFLSGKYLEETKEQSYQALIKSTKELCSYARSKGSMKVALEVFDYDID
                     KKSIIGPVELAERFARDITSEFDNFGLMVDLSHIPMIHETLEENLLPIKDYIIHAHMGN
                     TVIKDPSCEAYGDTHPRFGFPDSENDVDELTAYLRILMQIGFISEERRPIVSFEVKPWG
                     DEEPDIVVANAKRVLDLAWSRV"
     PFAM_domain     4812..5534
                     /aSDomain="AP_endonuc_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01261.26"
                     /description="Xylose isomerase-like TIM barrel"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_6_0006"
                     /evalue="1.20E-15"
                     /label="ctg30_6"
                     /locus_tag="ctg30_6"
                     /protein_end="277"
                     /protein_start="36"
                     /score="58.1"
                     /tool="antismash"
                     /translation="AADSYFDAIELTWIKDPQTRKNVRKMLDSSHMTVAYGGQPRLLTT
                     GMNINDLDESKRMAAVANLKEGIDEAYEMGASGFAFLSGKYLEETKEQSYQALIKSTKE
                     LCSYARSKGSMKVALEVFDYDIDKKSIIGPVELAERFARDITSEFDNFGLMVDLSHIPM
                     IHETLEENLLPIKDYIIHAHMGNTVIKDPSCEAYGDTHPRFGFPDSENDVDELTAYLRI
                     LMQIGFISEERRPIVSFEV"
     CDS             5712..6671
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 316.6; E-value: 2.1e-96)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_7"
                     /transl_table=11
                     /translation="MKIVVLDGYTLNPGDISWSGLEEHGELTVYDRTPADKIVERIGNA
                     EIIFTNKTPLTRETFDRCPEIRFVGVLATGYNVVDTEYAKSRGIPVTNIPTYGTAAVAQ
                     FAFALLLELCHHVGAHSDSVHKGDWTKCPDFCYWNYPLVELAGKTFGIIGFGRIGQAAA
                     RIAQAMGMKVLAYDQFFDPKLENDGLKYARLDELFAGSDVISLHCPLFPSTQGIINKTN
                     IAKMKDGVMIINTSRGPLVVEQDLAEALNSGKVAGAALDVVSTEPIGSGNVLLKAQNCI
                     ITPHIAWAPRESRNRLMNIAVDNLKAFLSGSPVNVVNL"
     PFAM_domain     6030..6572
                     /aSDomain="2-Hacid_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02826.21"
                     /description="D-isomer specific 2-hydroxyacid
                     dehydrogenase, NAD binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_7_0007"
                     /evalue="1.50E-60"
                     /label="ctg30_7"
                     /locus_tag="ctg30_7"
                     /protein_end="287"
                     /protein_start="106"
                     /score="203.7"
                     /tool="antismash"
                     /translation="FALLLELCHHVGAHSDSVHKGDWTKCPDFCYWNYPLVELAGKTFG
                     IIGFGRIGQAAARIAQAMGMKVLAYDQFFDPKLENDGLKYARLDELFAGSDVISLHCPL
                     FPSTQGIINKTNIAKMKDGVMIINTSRGPLVVEQDLAEALNSGKVAGAALDVVSTEPIG
                     SGNVLLKAQNCIITPHIA"
     CDS             6692..7846
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MKIVVAPDSFKGNLTALEVAEFIEAGIKQADKDIEVIKIPAADGG
                     EGTVEAIVAATGGKIIKQRVHGPFMEEMDSFFGISGDGKTAVIEMAACSGIMLVKKEEL
                     NPLYTTTYGVGELILAARNLGCRKINLGIGGSVTNDGGMGMAQALGYKFYDRQNKLLGQ
                     GGKYLCEVAGIDSSGFIKEIDGIEIITACDVNNPLYGPDGAAYIYGPQKGADAETIQFL
                     DKGLRHFAEVIKRDLGKDIAAIPGSGAAGGLGGGLLAFLNNARLCSGIDMVVSSCNFEE
                     AVRNCDLLITGEGRTDSQTANGKVVAGLAKVAAKYGVPVVCLSGSLMEGYQKIYEHGVD
                     AAFSNIISPMTLEEAIRSSPQMLTQASYSIARLMLKIYSRAKAK"
     aSDomain        6695..7813
                     /aSDomain="TIGR00045"
                     /aSTool="tigrfam"
                     /description="TIGR00045: glycerate kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_8_0001"
                     /evalue="6.80E-143"
                     /identifier="TIGR00045"
                     /label="ctg30_8"
                     /locus_tag="ctg30_8"
                     /protein_end="374"
                     /protein_start="1"
                     /score="474.1"
                     /tool="antismash"
                     /translation="KIVVAPDSFKGNLTALEVAEFIEAGIKQADKDIEVIKIPAADGGE
                     GTVEAIVAATGGKIIKQRVHGPFMEEMDSFFGISGDGKTAVIEMAACSGIMLVKKEELN
                     PLYTTTYGVGELILAARNLGCRKINLGIGGSVTNDGGMGMAQALGYKFYDRQNKLLGQG
                     GKYLCEVAGIDSSGFIKEIDGIEIITACDVNNPLYGPDGAAYIYGPQKGADAETIQFLD
                     KGLRHFAEVIKRDLGKDIAAIPGSGAAGGLGGGLLAFLNNARLCSGIDMVVSSCNFEEA
                     VRNCDLLITGEGRTDSQTANGKVVAGLAKVAAKYGVPVVCLSGSLMEGYQKIYEHGVDA
                     AFSNIISPMTLEEAIRSSPQMLTQASYSIARLM"
     PFAM_domain     6698..7813
                     /aSDomain="Gly_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02595.17"
                     /description="Glycerate kinase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_8_0008"
                     /evalue="3.10E-137"
                     /label="ctg30_8"
                     /locus_tag="ctg30_8"
                     /protein_end="374"
                     /protein_start="2"
                     /score="457.5"
                     /tool="antismash"
                     /translation="IVVAPDSFKGNLTALEVAEFIEAGIKQADKDIEVIKIPAADGGEG
                     TVEAIVAATGGKIIKQRVHGPFMEEMDSFFGISGDGKTAVIEMAACSGIMLVKKEELNP
                     LYTTTYGVGELILAARNLGCRKINLGIGGSVTNDGGMGMAQALGYKFYDRQNKLLGQGG
                     KYLCEVAGIDSSGFIKEIDGIEIITACDVNNPLYGPDGAAYIYGPQKGADAETIQFLDK
                     GLRHFAEVIKRDLGKDIAAIPGSGAAGGLGGGLLAFLNNARLCSGIDMVVSSCNFEEAV
                     RNCDLLITGEGRTDSQTANGKVVAGLAKVAAKYGVPVVCLSGSLMEGYQKIYEHGVDAA
                     FSNIISPMTLEEAIRSSPQMLTQASYSIARLM"
     CDS             8025..8567
                     /locus_tag="ctg30_9"
                     /transl_table=11
                     /translation="MTNRKLILYIAVSLDGFIADEGESLEWLLKTEGEGDNGYGGFYET
                     IDTVLLGRRTYDWIMRHENGNFPYKGKKCYVFSKSLKGKNEYVEFTDEEIPALVKNLKG
                     QEGGDIWIVGGGELLYCFIKERLVDRFIITVAPALIGRGIPLFKENDIEMDLELKSVRR
                     FNQFAELQYDYKGRPVL"
     PFAM_domain     8034..8519
                     /aSDomain="RibD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01872.19"
                     /description="RibD C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_9_0009"
                     /evalue="1.90E-20"
                     /label="ctg30_9"
                     /locus_tag="ctg30_9"
                     /protein_end="165"
                     /protein_start="3"
                     /score="73.7"
                     /tool="antismash"
                     /translation="RKLILYIAVSLDGFIADEGESLEWLLKTEGEGDNGYGGFYETIDT
                     VLLGRRTYDWIMRHENGNFPYKGKKCYVFSKSLKGKNEYVEFTDEEIPALVKNLKGQEG
                     GDIWIVGGGELLYCFIKERLVDRFIITVAPALIGRGIPLFKENDIEMDLELKSVRRFN"
     CDS             8969..10690
                     /NRPS_PKS="Domain: AMP-binding (26-460). E-value: 1.4e-86.
                     Score: 282.5. Matches aSDomain:
                     nrpspksdomains_ctg30_10_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     270.2; E-value: 4.6e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_10"
                     /sec_met_domain="AMP-binding (E-value: 8.6e-95, bitscore:
                     309.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKQALYNVRTVVNLKDMLNQSTFLYGNKAAFIVNNRGVNENISY
                     SRFKTDVDALGTALLELGLKDKCIAVIGENRYEWCVSYLAVTNGTGIVVPIDRELHVSE
                     INNILGRCNADAIIYSGKHNDSMKKLSTTVPSVKYFINMDESQDSDFYLSFKSLVERGK
                     ELLASGNLDYVDSEIDMDALAVLLFTSGTTGLAKGVMLSHRNICSNVVSVRSTVLVDTN
                     DTSLSILPMHHTYECTIGFLAFIYSGATISFNEGLKHIARNLKEMKPTVLVVVPLILEN
                     LYKKIWTQAGKQKFGRLKLKLALIITAILNHLFRIDIANRVFKQVHDNVGGRLRLILTG
                     AAAIDPSVSKGFRRMGIKVLQGYGLTECAPLVTGNRDHEYRDSSVGKALPGVEVKINNP
                     DENGVGEILVKGENVMLGYYKDEEETGRNLINGWFHTGDLGMVDKSGYVYITGRSKNII
                     ITNNGKNVYPEELEASINKNPCVQESLVSGEIDRTTGETHIHAHILPNLEYIKEKFKGV
                     SLTKDELLKLFNEIVKSINKDLPIYRRIRKFTLRESEFIKTTTKKIKRYCPENVEG"
     aSDomain        9047..10348
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_10_AMP-binding.1"
                     /evalue="1.40E-86"
                     /label="ctg30_10_AMP-binding.1"
                     /locus_tag="ctg30_10"
                     /protein_end="460"
                     /protein_start="26"
                     /score="282.5"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="GNKAAFIVNNRGVNENISYSRFKTDVDALGTALLELGLKDKCIAV
                     IGENRYEWCVSYLAVTNGTGIVVPIDRELHVSEINNILGRCNADAIIYSGKHNDSMKKL
                     STTVPSVKYFINMDESQDSDFYLSFKSLVERGKELLASGNLDYVDSEIDMDALAVLLFT
                     SGTTGLAKGVMLSHRNICSNVVSVRSTVLVDTNDTSLSILPMHHTYECTIGFLAFIYSG
                     ATISFNEGLKHIARNLKEMKPTVLVVVPLILENLYKKIWTQAGKQKFGRLKLKLALIIT
                     AILNHLFRIDIANRVFKQVHDNVGGRLRLILTGAAAIDPSVSKGFRRMGIKVLQGYGLT
                     ECAPLVTGNRDHEYRDSSVGKALPGVEVKINNPDENGVGEILVKGENVMLGYYKDEEET
                     GRNLINGWFHTGDLGMVDKSGYVYITGRSKNIIIT"
     PFAM_domain     9047..10348
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_10_0010"
                     /evalue="2.00E-88"
                     /label="ctg30_10"
                     /locus_tag="ctg30_10"
                     /protein_end="460"
                     /protein_start="26"
                     /score="296.9"
                     /tool="antismash"
                     /translation="GNKAAFIVNNRGVNENISYSRFKTDVDALGTALLELGLKDKCIAV
                     IGENRYEWCVSYLAVTNGTGIVVPIDRELHVSEINNILGRCNADAIIYSGKHNDSMKKL
                     STTVPSVKYFINMDESQDSDFYLSFKSLVERGKELLASGNLDYVDSEIDMDALAVLLFT
                     SGTTGLAKGVMLSHRNICSNVVSVRSTVLVDTNDTSLSILPMHHTYECTIGFLAFIYSG
                     ATISFNEGLKHIARNLKEMKPTVLVVVPLILENLYKKIWTQAGKQKFGRLKLKLALIIT
                     AILNHLFRIDIANRVFKQVHDNVGGRLRLILTGAAAIDPSVSKGFRRMGIKVLQGYGLT
                     ECAPLVTGNRDHEYRDSSVGKALPGVEVKINNPDENGVGEILVKGENVMLGYYKDEEET
                     GRNLINGWFHTGDLGMVDKSGYVYITGRSKNIIIT"
     CDS_motif       9518..9577
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg30_10_0001"
                     /evalue="3.60E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg30_10"
                     /protein_end="203"
                     /protein_start="183"
                     /score="22.6"
                     /tool="antismash"
                     /translation="AVLLFTSGTTGLAKGVMLSH"
     CDS_motif       10178..10243
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg30_10_0002"
                     /evalue="3.60E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg30_10"
                     /protein_end="425"
                     /protein_start="403"
                     /score="16.2"
                     /tool="antismash"
                     /translation="VGEILVKGENVMLGYYKDEEET"
     CDS             10914..12257
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 301.3; E-value: 1.8e-91)"
                     /gene_kind="transport"
                     /locus_tag="ctg30_11"
                     /transl_table=11
                     /translation="LFSKKELMRLFFPAFVEQFLSTAIGVVNTMMVSGLGAFAVSAVGI
                     VDSINFVAMNLFLSVATGATVVIAQHLGAGNQEKASNTAAQSIVSVFLLSALTGLGLFV
                     FGQQIIGFMFGGAEPVVKSAAWTYLVCSAISYPLLGLFNVFTGVLRANNNFIASMTSIV
                     ISNLVNLGVGAICIFKLDLGVLGAGLGLISARLVGAVVLLFHLLGSPKIHIRSASFKVS
                     FNIMKPVLYIGVPAGLDSLVFNGGKLLVQAIVASLGTASLAANSIAGSLNSIINIPGGA
                     VSIVAVSIIGYYAGAGDKQELKKMINRLTLYAMILLGGVSLLFLPFSSHILKLYQPADD
                     VLTMALHITYLTLACIPIFWPAAFIIPACLRSTGDVVYVTVVSILSMWLVRVLLGYLLV
                     KYTSLGIMGIWIAWCFDWVTRGVPFYARVLSRKYEKYIPARTDQTVTE"
     PFAM_domain     10950..11432
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_11_0011"
                     /evalue="3.10E-25"
                     /label="ctg30_11"
                     /locus_tag="ctg30_11"
                     /protein_end="173"
                     /protein_start="12"
                     /score="88.8"
                     /tool="antismash"
                     /translation="PAFVEQFLSTAIGVVNTMMVSGLGAFAVSAVGIVDSINFVAMNLF
                     LSVATGATVVIAQHLGAGNQEKASNTAAQSIVSVFLLSALTGLGLFVFGQQIIGFMFGG
                     AEPVVKSAAWTYLVCSAISYPLLGLFNVFTGVLRANNNFIASMTSIVISNLVNLGVG"
     aSDomain        10950..12143
                     /aSDomain="TIGR00797"
                     /aSTool="tigrfam"
                     /description="matE: MATE efflux family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_11_0002"
                     /evalue="1.10E-59"
                     /identifier="TIGR00797"
                     /label="ctg30_11"
                     /locus_tag="ctg30_11"
                     /protein_end="410"
                     /protein_start="12"
                     /score="200.3"
                     /tool="antismash"
                     /translation="PAFVEQFLSTAIGVVNTMMVSGLGAFAVSAVGIVDSINFVAMNLF
                     LSVATGATVVIAQHLGAGNQEKASNTAAQSIVSVFLLSALTGLGLFVFGQQIIGFMFGG
                     AEPVVKSAAWTYLVCSAISYPLLGLFNVFTGVLRANNNFIASMTSIVISNLVNLGVGAI
                     CIFKLDLGVLGAGLGLISARLVGAVVLLFHLLGSPKIHIRSASFKVSFNIMKPVLYIGV
                     PAGLDSLVFNGGKLLVQAIVASLGTASLAANSIAGSLNSIINIPGGAVSIVAVSIIGYY
                     AGAGDKQELKKMINRLTLYAMILLGGVSLLFLPFSSHILKLYQPADDVLTMALHITYLT
                     LACIPIFWPAAFIIPACLRSTGDVVYVTVVSILSMWLVRVLLGYLLVKYTSLGIMGIW"
     PFAM_domain     11616..12104
                     /aSDomain="MatE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01554.20"
                     /description="MatE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_11_0012"
                     /evalue="4.80E-20"
                     /label="ctg30_11"
                     /locus_tag="ctg30_11"
                     /protein_end="397"
                     /protein_start="234"
                     /score="71.9"
                     /tool="antismash"
                     /translation="PAGLDSLVFNGGKLLVQAIVASLGTASLAANSIAGSLNSIINIPG
                     GAVSIVAVSIIGYYAGAGDKQELKKMINRLTLYAMILLGGVSLLFLPFSSHILKLYQPA
                     DDVLTMALHITYLTLACIPIFWPAAFIIPACLRSTGDVVYVTVVSILSMWLVRVLLGYL
                     "
     CDS             12455..13204
                     /locus_tag="ctg30_12"
                     /transl_table=11
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQK
                     TVKKVDDAYFFIREVAMNGQDVLFVGTKKQAQDSIKEEADRSGQFFVNNRWLGGMLTNF
                     KTIRKRIDRLNQLNAMEADGTFEVLPKKEVIKLKKEMEDLEKNLGGIKNMKKIPGAMFV
                     VDPRKERNAILEAKKLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVKLIAAKIADAII
                     EGRQGEQLSPEAVETVEAVEVVEAAAE"
     aSDomain        12461..13132
                     /aSDomain="TIGR01011"
                     /aSTool="tigrfam"
                     /description="rpsB_bact: ribosomal protein uS2"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_12_0003"
                     /evalue="1.30E-110"
                     /identifier="TIGR01011"
                     /label="ctg30_12"
                     /locus_tag="ctg30_12"
                     /protein_end="226"
                     /protein_start="2"
                     /score="365.9"
                     /tool="antismash"
                     /translation="VISMKQLLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQKTV
                     KKVDDAYFFIREVAMNGQDVLFVGTKKQAQDSIKEEADRSGQFFVNNRWLGGMLTNFKT
                     IRKRIDRLNQLNAMEADGTFEVLPKKEVIKLKKEMEDLEKNLGGIKNMKKIPGAMFVVD
                     PRKERNAILEAKKLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVKLIAAKIADAIIEG
                     RQ"
     PFAM_domain     12479..13126
                     /aSDomain="Ribosomal_S2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00318.22"
                     /description="Ribosomal protein S2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_12_0013"
                     /evalue="1.20E-99"
                     /label="ctg30_12"
                     /locus_tag="ctg30_12"
                     /protein_end="224"
                     /protein_start="8"
                     /score="332.0"
                     /tool="antismash"
                     /translation="LLEAGVHFGHQTRRWNPKMAEYIFTERNGIYIIDLQKTVKKVDDA
                     YFFIREVAMNGQDVLFVGTKKQAQDSIKEEADRSGQFFVNNRWLGGMLTNFKTIRKRID
                     RLNQLNAMEADGTFEVLPKKEVIKLKKEMEDLEKNLGGIKNMKKIPGAMFVVDPRKERN
                     AILEAKKLGIPVVAIVDTNCDPDEVDFVIPGNDDAIRAVKLIAAKIADAIIEG"
     CDS             13404..14051
                     /locus_tag="ctg30_13"
                     /transl_table=11
                     /translation="MITAEMVRQLRERTGAGMMDCKKALTETNGDADKAVEYLREKGIA
                     KAASKAGRIAAEGLVESYIHGGGRIGVLVEVNIETDFAAKNEEFKQLVKDIAMQIAASK
                     PEFVRREEVPASVLEAEKEILRAQARNEGKPEKIIDKMVEGRIDKYYGEKCLMEQAFIK
                     DPDITVDQLIKEKIAHIGENITVRRFVRFERGEGIEKKEENFADEVMKQIGG"
     aSDomain        13407..13685
                     /aSDomain="TIGR00116"
                     /aSTool="tigrfam"
                     /description="tsf: translation elongation factor Ts"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_13_0004"
                     /evalue="4.50E-37"
                     /identifier="TIGR00116"
                     /label="ctg30_13"
                     /locus_tag="ctg30_13"
                     /protein_end="94"
                     /protein_start="1"
                     /score="125.8"
                     /tool="antismash"
                     /translation="ITAEMVRQLRERTGAGMMDCKKALTETNGDADKAVEYLREKGIAK
                     AASKAGRIAAEGLVESYIHGGGRIGVLVEVNIETDFAAKNEEFKQLVK"
     PFAM_domain     13494..13991
                     /aSDomain="EF_TS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00889.21"
                     /description="Elongation factor TS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_13_0014"
                     /evalue="5.70E-45"
                     /label="ctg30_13"
                     /locus_tag="ctg30_13"
                     /protein_end="196"
                     /protein_start="30"
                     /score="153.6"
                     /tool="antismash"
                     /translation="DADKAVEYLREKGIAKAASKAGRIAAEGLVESYIHGGGRIGVLVE
                     VNIETDFAAKNEEFKQLVKDIAMQIAASKPEFVRREEVPASVLEAEKEILRAQARNEGK
                     PEKIIDKMVEGRIDKYYGEKCLMEQAFIKDPDITVDQLIKEKIAHIGENITVRRFVRFE
                     RGE"
     aSDomain        13674..14042
                     /aSDomain="TIGR00116"
                     /aSTool="tigrfam"
                     /description="tsf: translation elongation factor Ts"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_13_0005"
                     /evalue="5.50E-41"
                     /identifier="TIGR00116"
                     /label="ctg30_13"
                     /locus_tag="ctg30_13"
                     /protein_end="213"
                     /protein_start="90"
                     /score="138.6"
                     /tool="antismash"
                     /translation="QLVKDIAMQIAASKPEFVRREEVPASVLEAEKEILRAQARNEGKP
                     EKIIDKMVEGRIDKYYGEKCLMEQAFIKDPDITVDQLIKEKIAHIGENITVRRFVRFER
                     GEGIEKKEENFADEVMKQI"
     CDS             14186..14893
                     /locus_tag="ctg30_14"
                     /transl_table=11
                     /translation="MSEIKYRRIMLKISGEALSGEKGNGIDTNTVNEICDRILAVHNLG
                     VEIAIVVGGGNFWRGRSGKGMDRTTADHMGMLATVINSLGLQDALESRGIQVRVQTAIE
                     MRQIAEPYVRRKAVRHLEKKRIVIFACGMGNPYFSTDTAAALRAAEIDAQAILMAKNVD
                     GIYDSDPSKNPDAVKYNKLSYQEYLNKNLCAIDLTAASFCKDNGIPTLVFGLNDPDNII
                     RAVKGEEIGTTIY"
     aSDomain        14201..14887
                     /aSDomain="TIGR02075"
                     /aSTool="tigrfam"
                     /description="pyrH_bact: UMP kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_14_0006"
                     /evalue="2.70E-91"
                     /identifier="TIGR02075"
                     /label="ctg30_14"
                     /locus_tag="ctg30_14"
                     /protein_end="234"
                     /protein_start="5"
                     /score="303.3"
                     /tool="antismash"
                     /translation="YRRIMLKISGEALSGEKGNGIDTNTVNEICDRILAVHNLGVEIAI
                     VVGGGNFWRGRSGKGMDRTTADHMGMLATVINSLGLQDALESRGIQVRVQTAIEMRQIA
                     EPYVRRKAVRHLEKKRIVIFACGMGNPYFSTDTAAALRAAEIDAQAILMAKNVDGIYDS
                     DPSKNPDAVKYNKLSYQEYLNKNLCAIDLTAASFCKDNGIPTLVFGLNDPDNIIRAVKG
                     EEIGTTI"
     PFAM_domain     14207..14824
                     /aSDomain="AA_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00696.30"
                     /description="Amino acid kinase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_14_0015"
                     /evalue="7.60E-29"
                     /label="ctg30_14"
                     /locus_tag="ctg30_14"
                     /protein_end="213"
                     /protein_start="7"
                     /score="101.1"
                     /tool="antismash"
                     /translation="RIMLKISGEALSGEKGNGIDTNTVNEICDRILAVHNLGVEIAIVV
                     GGGNFWRGRSGKGMDRTTADHMGMLATVINSLGLQDALESRGIQVRVQTAIEMRQIAEP
                     YVRRKAVRHLEKKRIVIFACGMGNPYFSTDTAAALRAAEIDAQAILMAKNVDGIYDSDP
                     SKNPDAVKYNKLSYQEYLNKNLCAIDLTAASFCKDNGIPTLVF"
     CDS             15005..15562
                     /locus_tag="ctg30_15"
                     /transl_table=11
                     /translation="MDKELYKPIEEKMKKTINVLKDNLAGIRAGRANPQILDKITIDYY
                     GAPTPIQQVATVSVPEARVILIQPWEAKLLKDIEKEIQKSDIGINPNNDGKMLRLVFPA
                     LTEERRKELTKSVKKEGEEAKVAIRAIRRDSIEHMKAKKKSSEITEDDLKDAEKDIQNL
                     TDKFIAEIDRIVEAKDKEIMEV"
     aSDomain        15032..15559
                     /aSDomain="TIGR00496"
                     /aSTool="tigrfam"
                     /description="frr: ribosome recycling factor"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_15_0007"
                     /evalue="7.60E-67"
                     /identifier="TIGR00496"
                     /label="ctg30_15"
                     /locus_tag="ctg30_15"
                     /protein_end="185"
                     /protein_start="9"
                     /score="222.3"
                     /tool="antismash"
                     /translation="EEKMKKTINVLKDNLAGIRAGRANPQILDKITIDYYGAPTPIQQV
                     ATVSVPEARVILIQPWEAKLLKDIEKEIQKSDIGINPNNDGKMLRLVFPALTEERRKEL
                     TKSVKKEGEEAKVAIRAIRRDSIEHMKAKKKSSEITEDDLKDAEKDIQNLTDKFIAEID
                     RIVEAKDKEIMEV"
     PFAM_domain     15062..15553
                     /aSDomain="RRF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01765.21"
                     /description="Ribosome recycling factor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_15_0016"
                     /evalue="1.90E-62"
                     /label="ctg30_15"
                     /locus_tag="ctg30_15"
                     /protein_end="183"
                     /protein_start="19"
                     /score="210.1"
                     /tool="antismash"
                     /translation="LKDNLAGIRAGRANPQILDKITIDYYGAPTPIQQVATVSVPEARV
                     ILIQPWEAKLLKDIEKEIQKSDIGINPNNDGKMLRLVFPALTEERRKELTKSVKKEGEE
                     AKVAIRAIRRDSIEHMKAKKKSSEITEDDLKDAEKDIQNLTDKFIAEIDRIVEAKDKEI
                     M"
     CDS             15559..15750
                     /locus_tag="ctg30_16"
                     /transl_table=11
                     /translation="MNRLIGYTLGDAFKLAREEGFEIGEITITSPPKMEILEYDDSFRV
                     LRVNTSENKLNILVCKPL"
     CDS             15870..16637
                     /locus_tag="ctg30_17"
                     /transl_table=11
                     /translation="VGIWDSVARLLGRKKDVKQEFASIPKHIAIIPDGNGRWAKKRGLP
                     RNVGHREGSMALKKVVIYCSEAGVKYLTVYAFSTENWKRPKSEVDALMSLLVEFLRNAE
                     KELDGSNVKIKVIGDVKGLPEELQKEIIRVEKLTGINNGLNLNICLNYGGRLELLHAVK
                     EIAVKVKSGNLKIDEIDEKQFESCLYTAGIPEPDLLIRTSGEQRISNFLLWQCAYTEFW
                     FINELWPDVNGSHIAEAIRAYEKRNRRFGGLEQ"
     aSDomain        15939..16622
                     /aSDomain="TIGR00055"
                     /aSTool="tigrfam"
                     /description="uppS:
                     di-trans,poly-cis-decaprenylcistransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_17_0008"
                     /evalue="7.50E-90"
                     /identifier="TIGR00055"
                     /label="ctg30_17"
                     /locus_tag="ctg30_17"
                     /protein_end="251"
                     /protein_start="23"
                     /score="298.3"
                     /tool="antismash"
                     /translation="IPKHIAIIPDGNGRWAKKRGLPRNVGHREGSMALKKVVIYCSEAG
                     VKYLTVYAFSTENWKRPKSEVDALMSLLVEFLRNAEKELDGSNVKIKVIGDVKGLPEEL
                     QKEIIRVEKLTGINNGLNLNICLNYGGRLELLHAVKEIAVKVKSGNLKIDEIDEKQFES
                     CLYTAGIPEPDLLIRTSGEQRISNFLLWQCAYTEFWFINELWPDVNGSHIAEAIRAYEK
                     RNRRFG"
     PFAM_domain     15960..16622
                     /aSDomain="Prenyltransf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01255.21"
                     /description="Putative undecaprenyl diphosphate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_17_0017"
                     /evalue="1.20E-79"
                     /label="ctg30_17"
                     /locus_tag="ctg30_17"
                     /protein_end="251"
                     /protein_start="30"
                     /score="267.0"
                     /tool="antismash"
                     /translation="IPDGNGRWAKKRGLPRNVGHREGSMALKKVVIYCSEAGVKYLTVY
                     AFSTENWKRPKSEVDALMSLLVEFLRNAEKELDGSNVKIKVIGDVKGLPEELQKEIIRV
                     EKLTGINNGLNLNICLNYGGRLELLHAVKEIAVKVKSGNLKIDEIDEKQFESCLYTAGI
                     PEPDLLIRTSGEQRISNFLLWQCAYTEFWFINELWPDVNGSHIAEAIRAYEKRNRRFG"
     CDS             16707..17534
                     /locus_tag="ctg30_18"
                     /transl_table=11
                     /translation="MLKTRVISALVGLILLIAVLYLGSIVLGVVVSIIAAIGLYEFYNS
                     AAKLKNIHPIKPVGYLSIIPLLLLGLEETGWYRLDLGILTGISVCVVIFLSMAFIVFGH
                     KRYNIIDACVTAFGIAYVPFLMSFLILIRKMDFGILLIWLIFIGAWGTDTMAYTFGRLF
                     GKRKIVPEISKNKTMAGAIGGILGCVALMFVFGLISRSFFGLELSTAALVLLGLFCGVI
                     SQIGDWSASAVKRYVNVKDYGSIMPGHGGVLDRFDSILFVAPVVYYVIVVCNI"
     PFAM_domain     16713..17519
                     /aSDomain="CTP_transf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01148.22"
                     /description="Cytidylyltransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_18_0018"
                     /evalue="2.20E-54"
                     /label="ctg30_18"
                     /locus_tag="ctg30_18"
                     /protein_end="271"
                     /protein_start="2"
                     /score="185.1"
                     /tool="antismash"
                     /translation="KTRVISALVGLILLIAVLYLGSIVLGVVVSIIAAIGLYEFYNSAA
                     KLKNIHPIKPVGYLSIIPLLLLGLEETGWYRLDLGILTGISVCVVIFLSMAFIVFGHKR
                     YNIIDACVTAFGIAYVPFLMSFLILIRKMDFGILLIWLIFIGAWGTDTMAYTFGRLFGK
                     RKIVPEISKNKTMAGAIGGILGCVALMFVFGLISRSFFGLELSTAALVLLGLFCGVISQ
                     IGDWSASAVKRYVNVKDYGSIMPGHGGVLDRFDSILFVAPVVYYVIV"
     CDS             17761..18909
                     /locus_tag="ctg30_19"
                     /transl_table=11
                     /translation="MAKIISIIGSTGSIGVQTLDVARNLGIKVAAMSANSNIDLLEKQV
                     HEFKPRLVSVGSRELASELKARLAGMKVQVLSGLEGMLGVVEVQEADTVVTSVVGTAGL
                     IPTMHAIKNRKNIALANKETLVTAGQLVMEEAKKQGVAIFPVDSEHSAIYQCLMGNSDR
                     QVEKIIITASGGPFRGRTLEELRDITPAQALKHPNWSMGSKITVDSATLMNKGLEVIEA
                     KWLFGRELDKIQVLVHPQSIIHSMVEYVDGSVMAQLGSPDMRIPIQLALTYPDRCGNNF
                     SRLDFLKCSQLTFEEPDTKTFRCLQLAYDAMSTGGTMTAAMNAANEAAVSAFLNNRIAF
                     TAIPEIIEKIMMLHKVNICPGLDDIIEVDNWARTQAEKAVNG"
     aSDomain        17767..18900
                     /aSDomain="TIGR00243"
                     /aSTool="tigrfam"
                     /description="Dxr: 1-deoxy-D-xylulose 5-phosphate
                     reductoisomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_19_0009"
                     /evalue="2.20E-155"
                     /identifier="TIGR00243"
                     /label="ctg30_19"
                     /locus_tag="ctg30_19"
                     /protein_end="380"
                     /protein_start="2"
                     /score="515.3"
                     /tool="antismash"
                     /translation="KIISIIGSTGSIGVQTLDVARNLGIKVAAMSANSNIDLLEKQVHE
                     FKPRLVSVGSRELASELKARLAGMKVQVLSGLEGMLGVVEVQEADTVVTSVVGTAGLIP
                     TMHAIKNRKNIALANKETLVTAGQLVMEEAKKQGVAIFPVDSEHSAIYQCLMGNSDRQV
                     EKIIITASGGPFRGRTLEELRDITPAQALKHPNWSMGSKITVDSATLMNKGLEVIEAKW
                     LFGRELDKIQVLVHPQSIIHSMVEYVDGSVMAQLGSPDMRIPIQLALTYPDRCGNNFSR
                     LDFLKCSQLTFEEPDTKTFRCLQLAYDAMSTGGTMTAAMNAANEAAVSAFLNNRIAFTA
                     IPEIIEKIMMLHKVNICPGLDDIIEVDNWARTQAEKAV"
     PFAM_domain     17773..18147
                     /aSDomain="DXP_reductoisom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02670.18"
                     /description="1-deoxy-D-xylulose 5-phosphate
                     reductoisomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_19_0019"
                     /evalue="5.20E-38"
                     /label="ctg30_19"
                     /locus_tag="ctg30_19"
                     /protein_end="129"
                     /protein_start="4"
                     /score="130.8"
                     /tool="antismash"
                     /translation="ISIIGSTGSIGVQTLDVARNLGIKVAAMSANSNIDLLEKQVHEFK
                     PRLVSVGSRELASELKARLAGMKVQVLSGLEGMLGVVEVQEADTVVTSVVGTAGLIPTM
                     HAIKNRKNIALANKETLVTAG"
     PFAM_domain     18187..18438
                     /aSDomain="DXP_redisom_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08436.14"
                     /description="1-deoxy-D-xylulose 5-phosphate
                     reductoisomerase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_19_0020"
                     /evalue="8.40E-42"
                     /label="ctg30_19"
                     /locus_tag="ctg30_19"
                     /protein_end="226"
                     /protein_start="142"
                     /score="141.3"
                     /tool="antismash"
                     /translation="IFPVDSEHSAIYQCLMGNSDRQVEKIIITASGGPFRGRTLEELRD
                     ITPAQALKHPNWSMGSKITVDSATLMNKGLEVIEAKWLF"
     PFAM_domain     18532..18882
                     /aSDomain="DXPR_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13288.8"
                     /description="DXP reductoisomerase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_19_0021"
                     /evalue="1.00E-42"
                     /label="ctg30_19"
                     /locus_tag="ctg30_19"
                     /protein_end="374"
                     /protein_start="257"
                     /score="145.2"
                     /tool="antismash"
                     /translation="LGSPDMRIPIQLALTYPDRCGNNFSRLDFLKCSQLTFEEPDTKTF
                     RCLQLAYDAMSTGGTMTAAMNAANEAAVSAFLNNRIAFTAIPEIIEKIMMLHKVNICPG
                     LDDIIEVDNWART"
     CDS             18949..20241
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_20"
                     /sec_met_domain="Peptidase_M50 (E-value: 1e-71, bitscore:
                     232.9, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIVLAILALSFLIIIHELGHFMVAKAFKVRVNEFSLFMGPKLFS
                     FQKGETLYSLRLIPLGGYVKMEGEEEASEDDRAYNKKPIGVRAAIIAAGPLMNILTALV
                     FAFIIISQTGYFTTQIKDIVPGSAAEKYDLRVGDKLQKYNGKTLFNVNDLGIFSYPLTN
                     ESITLQYERNGVSKTVELTPERENFILGFTPLQDELEGPDSNVVKAVSDNSPAIKAGLK
                     VNDRIVEINGADIRTRKDIRDILQQNQDKNVNILVERAGELQKLKPVVPLKSKNPEYYA
                     IGILDFVHEKGSIGSTIKEAAKYNIFISRSIYYSLGWLFTGTVPASELMGPVGITTTIS
                     NEVAESQSLKETVIRLLSITTMISINLGLVNLIPFPALDGSKLVLLLIEGIRKKPLNPE
                     KEALITMVGMVILIMLMLYATFNDILRIGKG"
     aSDomain        18952..20229
                     /aSDomain="TIGR00054"
                     /aSTool="tigrfam"
                     /description="TIGR00054: RIP metalloprotease RseP"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg30_20_0010"
                     /evalue="6.40E-86"
                     /identifier="TIGR00054"
                     /label="ctg30_20"
                     /locus_tag="ctg30_20"
                     /protein_end="427"
                     /protein_start="1"
                     /score="286.8"
                     /tool="antismash"
                     /translation="GIVLAILALSFLIIIHELGHFMVAKAFKVRVNEFSLFMGPKLFSF
                     QKGETLYSLRLIPLGGYVKMEGEEEASEDDRAYNKKPIGVRAAIIAAGPLMNILTALVF
                     AFIIISQTGYFTTQIKDIVPGSAAEKYDLRVGDKLQKYNGKTLFNVNDLGIFSYPLTNE
                     SITLQYERNGVSKTVELTPERENFILGFTPLQDELEGPDSNVVKAVSDNSPAIKAGLKV
                     NDRIVEINGADIRTRKDIRDILQQNQDKNVNILVERAGELQKLKPVVPLKSKNPEYYAI
                     GILDFVHEKGSIGSTIKEAAKYNIFISRSIYYSLGWLFTGTVPASELMGPVGITTTISN
                     EVAESQSLKETVIRLLSITTMISINLGLVNLIPFPALDGSKLVLLLIEGIRKKPLNPEK
                     EALITMVGMVILIMLMLYATFNDILRI"
     PFAM_domain     18964..20193
                     /aSDomain="Peptidase_M50"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02163.24"
                     /description="Peptidase family M50"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg30_20_0022"
                     /evalue="1.90E-71"
                     /label="ctg30_20"
                     /locus_tag="ctg30_20"
                     /protein_end="415"
                     /protein_start="5"
                     /score="240.6"
                     /tool="antismash"
                     /translation="AILALSFLIIIHELGHFMVAKAFKVRVNEFSLFMGPKLFSFQKGE
                     TLYSLRLIPLGGYVKMEGEEEASEDDRAYNKKPIGVRAAIIAAGPLMNILTALVFAFII
                     ISQTGYFTTQIKDIVPGSAAEKYDLRVGDKLQKYNGKTLFNVNDLGIFSYPLTNESITL
                     QYERNGVSKTVELTPERENFILGFTPLQDELEGPDSNVVKAVSDNSPAIKAGLKVNDRI
                     VEINGADIRTRKDIRDILQQNQDKNVNILVERAGELQKLKPVVPLKSKNPEYYAIGILD
                     FVHEKGSIGSTIKEAAKYNIFISRSIYYSLGWLFTGTVPASELMGPVGITTTISNEVAE
                     SQSLKETVIRLLSITTMISINLGLVNLIPFPALDGSKLVLLLIEGIRKKPLNPEKEALI
                     TMVGMVILIML"
ORIGIN
        1 cttttccaaa gagaccaccc tgcttttttc aatttcagaa aacagaatca aatccagcag
       61 aagtttcttt tgatagtcta catgagagtt ccaattacac aacattaata tagcctccaa
      121 aaccagtgtt atggcaatta ataccatacg ctgtggtttt caaatttttg gaagctaatg
      181 tcaaggtgta cagtaaccat atatggttac tactggtaaa tgttgttgga aaatttaaag
      241 taaaaaactg gagaatgtta gaggtgcgag aagaaaattg catcttaaaa catagagctc
      301 gaaagctatt ggagttttcg agagtattat aaaaattgag aggggatttt tattatgaca
      361 agaactgaac tgatcaacga attaagaaag tacagatgtg cggatttatc cgatgccatg
      421 gatgccctgg gaatggtgaa tgtcggttca atgaacccaa acatgaaacc tttaaggccc
      481 ggaatggaat ttaaaggttt tgcctatacg gtaaaactgc ttcctaaaca gactcccaat
      541 aagcagtgta aaacagttgc ggaatacaag gaagaattga ccagggaatg tgaaaacata
      601 tactccttcg taaacgatat cacacccgaa aatgcaaagg acatggttgt ggtcattgac
      661 atggaaggca tcgtgggagg aatatggggc tcggaaatag caatgaacat gatgataagg
      721 ggaattgaag gtgctgtaat agatggggcc tgcagagact catatgaaac taatcttgaa
      781 aaggcaaatg tattctgcac ccagagaacc tacaaccatg tatacggacg tgcccgcgga
      841 ggagccagaa acataccggt tcattgtgcg ggagtgaccg taaaaccagg agatatcata
      901 tgcgcagatg atgacggtgt tctggtcata ccatatgaag ttgccgaaga tgtcattaaa
      961 tttgccagat tgcagctgga agaggatatt gccacaagat cttcgcacta tgaaaaattg
     1021 ggttttgaac ctgatgcaac tcttgaaaga aacagatgat tttttagtat tccatacaaa
     1081 aacggctgtt acattatctt attatgaaac agcctgtttt gtaaaattta agaaaggggg
     1141 tttctatgaa agccatacaa aaaacagccg gaaagcccgg agcacagttt gttgagttgg
     1201 aaattcccag gcccgggagg aatgaagtcc ttgtacaggt caaggcagcc gccctgtgca
     1261 ggtcggatgt ggatgtatat gaatggacgc agctggtcca gaatgcccat tataaactgc
     1321 cgtttaccat gggccatgaa ttttcaggga ttgtggttga agtaggtgcg gatgtaaagg
     1381 gaatcagggc gggggacagg gttgcgggtg agacacatat tccctgcggc tgctgcaata
     1441 cctgcaggac cggcaaccag cacatctgca ggaacaatat gggcgtgata ggcaggagct
     1501 tcgacgggtg ttttgcccaa tacataaaaa ttcctgaaat agcggcagtt aaacttcccg
     1561 attccataac ctacaggcag ggtgcactgc tggaaccttt taccacagcc atgcacgccc
     1621 tttcaaaagc aaatccctcc ggcagcagca cagccatttt gggaatgggc accatcggat
     1681 tgatggctgt tgagcttgca aaatttttag gcagtaccaa aatctttgcc atgggcaata
     1741 atgagctgcg gcttgcagag agcagacgcc ttggtgcaga tgtggccatc aatggttcca
     1801 gggaggattt tgtgcaggct ataatgaggg aaacaaatgg agtaggggtt gcttcaatca
     1861 tagatatgac cggaaacgaa gacgtaataa ataagagcgt tgaggcttta aaggtggcag
     1921 gaacccttgt tcatgtggga atggtgccaa agccgctgac ctttaacaat tatatgtacg
     1981 gtgtggtgta caaggaactg aatgttaccg ggatattcgg caggaggatg ttcgaaagct
     2041 gggaaaccgt actgtccata ttgagcaccg gcaggatcgg gttggacaat tacattggga
     2101 aggtaacaga gcttgaaaat tttgagcagg ccatagccga tttcagaggt gtaacaggaa
     2161 gaataatttt tgagctttaa tatagaaaaa gaaggtgtaa agatgatagc aaatcacaac
     2221 tgcaaagagg tcagtatttt tgaggtgggt ccccgggacg gcctgcagcc cgaaccggta
     2281 ttcataccta ctgaaaagaa gattgaactg gtaaataggc tgacggatgc gggatgcaaa
     2341 agaatagagg tcacttcctt cgtacatccc aggtgggtgc ctcagatggc cgacagcaag
     2401 gaagttctgg ccggcataag aaaaaaggaa ggtgtcacat ataacgcatt gatccctaat
     2461 ttgagagggc ttgaattagc tatggaatgc ggcttgaagg aagtggtcac catcatgagt
     2521 accagtgaaa gccacaataa aaagaacctt aacatgagta ccggagattc tcttaaagaa
     2581 atagaacaaa taaataaagt tgcggcaaaa aacggtgtta aggtacgttc atatatagca
     2641 actgtcttcg ggtgtcccat cgaaggggaa atgagtccca aaagggctct tgagatagca
     2701 ttgaaactgg aagagtacgg ctcttatgaa atttcacttg gagatacaac cggaatggca
     2761 aatccggttt cggcatatga aatcccaaaa atgataaacg aaaaacttac cggagcaaag
     2821 cttgctgttc actatcataa ataccacggt cttgaatttg caaataacct ggcatccttc
     2881 gaggccggta tcagaatatt tgacggcgca gccggaggcc ttggaggctg tccttatgca
     2941 cccggtgcca agggaaactg tcagactgaa atactggtgg agatgttcca ccgaatggga
     3001 attgaaacag gaatagatct gaaacagatt tatgaggcag gggagtatgc tcaaaccttg
     3061 agcacacttt tgcacagcag atgtgtataa gagcctgttc aatatctcat tgtacccgtc
     3121 attctggctg attttgcgcc atgccacgtt aaattttctt gcaataaaca aattattact
     3181 tcgaaaattt gccttgcctg acacaaaatc cacctgagat gccggacaca agcagatatt
     3241 aaacaggctc taaaagagcc ggagttataa agggggagag gtttaaaaat gaatgcaaag
     3301 ttgttggaca taaagaaaaa atacatatcc ggagatatta aaagccagaa ccttgagagt
     3361 gccattttca cccaagtcta tggagcagat ccggaaaata taagggaagc atgcaatgat
     3421 gcggcttatg tccgttgtga agcagttgag gaagcaacgg gagccagcct tgatattata
     3481 aaaaataccc gcctggacaa ctgttcactg gttggagggg acagaatcct ggccggaatt
     3541 gaagggaaaa taggtgcggc cactataccc atgggaatag ccggccctgt aaaaatcaac
     3601 ggacagtttg tggatgaaaa ggtatatatt ccgcttgcca ccaacgaggc agctctggtt
     3661 gcgggagttc aaaggggaat caaggcgatt aatatggcag gagggctgaa cacactggtg
     3721 cattttgacg gaatgaccag agcacctttg atagaagctc ccaatatcgc cgaggccaga
     3781 agattctgca ggcagatagt aacggataag gtgctgttca aggaactggc cgtgctgtca
     3841 agggacccct ttgtacggct tgagcagatc gatccctatc agctgggtac caaagtattc
     3901 ttgagaatga cctttaaaac aggtgatgca atggggatga acggtgtgac aaaagcttcg
     3961 gcagatatta caagagggat tctggcaaaa atgccccaat ggaagcttat aaccataagc
     4021 agtaatcttt gctcggataa aaaatcctcc catatcaatg tattgaacgg ccgcggaaaa
     4081 tccatacaga ctgaggtatt cattccggat gaggttttaa aggccgtatt taaaaaggga
     4141 gtaaacgcca gaagtgttga gaagactgtt ttccataaat gttatctggg ctcctgctac
     4201 agcggaacca tagccggctt caacgtaaat gcggcaaatg cggtggcggc attttacgcg
     4261 gccaccggac aggatctggc acatgtcatt tcctcctcca gctgctttgt gcaggctgat
     4321 gcagccgaag gcggtgtcca ttttatggtt tccctgccct gcatggagct ggcaaccatc
     4381 ggagggggca cgatgttcgg aactgcaaag gaagccttaa ggctcatcgg ctgcggaggc
     4441 ttcggaaaga gtgtggacga taatgtgaat gtactgagat tggctgaaat tgcggcaaca
     4501 gccgtaacgg cgcttgagtt gaacactgcc tgtgcccagg cggcagggta tgaaatggca
     4561 gattcccatg tcaagcttgc aaggggcgag gaagcctagt gtgcatggcc aattaacctc
     4621 cttcattcgc tacattgcga taaaggatat aagttttcat cactttttgt gccttgagca
     4681 cagcgaaagg aatgatagtt aatatgtacg aatccataaa aaagtatatg aaggtgggcc
     4741 tgattcattt tatggcctat cccgccacaa tgaaaggtga agggcctatt gaagagactg
     4801 tgaaaaagat tgctgcagac agttactttg atgcaatcga gttaacctgg atcaaagacc
     4861 cgcagacaag aaagaatgtc aggaaaatgc tggacagttc ccacatgacg gtggcttacg
     4921 ggggacagcc cagattgctc actaccggta tgaatataaa cgacctggat gagagcaaaa
     4981 ggatggcagc tgttgcaaat ctgaaggagg gaattgatga ggcgtatgaa atgggagctt
     5041 caggctttgc ctttttgtca ggcaaatatc tggaggaaac aaaggagcag tcctatcagg
     5101 ctttgattaa atctacaaag gaattgtgca gctatgccag gagcaagggc agtatgaagg
     5161 tagcgctgga agtctttgac tacgatatag acaagaagtc cattatcggc cctgttgagc
     5221 ttgcagaacg atttgcacgg gacataactt cggaatttga taatttcggt ttaatggtgg
     5281 acctgtccca tatcccgatg attcatgaaa cacttgaaga aaatctgctt cccataaaag
     5341 actatataat acacgcacat atgggcaaca ccgtcataaa ggatccatcc tgcgaggcct
     5401 atggagatac acatccgcgt ttcggctttc ccgattcgga aaatgatgtg gatgaattga
     5461 cggcatattt gagaatactg atgcagatcg gtttcatcag cgaagagcgc aggcccatag
     5521 tcagctttga ggtaaagccc tggggcgatg aggagccgga tattgtcgtg gcaaatgcaa
     5581 agagagtact ggatctggcc tggtcaagag tttgaggtca catatagcat aatctttgca
     5641 gatttatcca cagcgaagaa caaagttgcg cagcggtttt gttcttgcag gttattacga
     5701 ggagggcgat tatgaaaata gtagtactgg acggatatac tcttaatccg ggtgacatca
     5761 gctggtcggg attggaggag cacggagaac tgacggtata tgacaggact ccggcagata
     5821 agattgttga gaggatcggc aatgctgaaa ttatttttac aaacaagaca ccgcttacaa
     5881 gggaaacctt tgacaggtgc cctgaaataa ggtttgtagg tgtactggcc acaggctata
     5941 atgtggttga taccgagtac gcaaagtcca gaggcatacc tgtgacaaat atacctacct
     6001 atggtactgc tgcagtggct caattcgctt ttgcactgct tttagagctt tgtcatcatg
     6061 tgggagccca cagtgacagt gtacataagg gtgattggac gaaatgtcct gatttctgct
     6121 actggaatta tcctctggtt gaacttgccg gtaaaacctt cggcattatc ggttttggca
     6181 gaatagggca ggcagctgcc aggattgctc aggccatggg tatgaaggtg ctggcctatg
     6241 accagttttt cgatcccaaa ctggaaaatg acgggctgaa atatgcccgg ttggatgaac
     6301 tgtttgcagg gtcggacgtt atctcactgc actgtccgct gtttccttca acccagggca
     6361 taataaataa aacaaatatt gcaaaaatga aggatggggt aatgatcata aatacgtcca
     6421 gaggtcccct ggtagtggaa caggacctgg cggaggctct taattccgga aaggtggcag
     6481 gagcggcact ggatgttgtg tcgaccgagc ccatcggcag cggcaatgta ttgctcaaag
     6541 cccaaaattg cattattaca ccccatatag cctgggcacc aagggaatcc agaaacaggc
     6601 tgatgaacat cgcagtcgat aatctgaagg cgtttttatc aggcagtccg gtaaatgtag
     6661 tgaacctgta agagggtgaa aggatgattc aatgaaaatc gtggttgcac ctgattcgtt
     6721 taaaggtaat ctgactgctc tggaagtggc tgaatttata gaagccggta taaagcaggc
     6781 cgataaagat atcgaggtaa taaagattcc cgctgccgat ggcggtgagg gcacggttga
     6841 ggctattgtt gccgcaaccg gcggtaaaat aataaaacag cgggttcatg gcccgtttat
     6901 ggaggaaatg gactcctttt tcggcatttc aggggatgga aaaacagctg tcattgaaat
     6961 ggccgcatgc tcaggaatca tgctggtcaa aaaagaggaa ctcaaccctc tgtacacaac
     7021 cacatacggt gtgggggaat tgatattggc tgccagaaat cttgggtgcc gaaaaataaa
     7081 cctgggcatc ggtggaagtg tgaccaatga tggcggtatg gggatggcgc aggccctggg
     7141 atataaattc tacgacaggc aaaataaact gttgggtcag ggcggaaaat atttgtgtga
     7201 agtggcagga attgattcaa gtggctttat aaaagaaata gacggaattg agatcataac
     7261 tgcctgcgat gtaaataatc cattatacgg gccagacgga gctgcttata tatacggacc
     7321 tcaaaaaggt gccgatgcag aaacaataca gtttcttgac aaagggttga ggcactttgc
     7381 cgaagttatc aaaagagatc ttggcaaaga tattgccgcc attccgggaa gcggtgccgc
     7441 cggaggcctt ggcggcggcc tgctggcttt tttgaacaac gccaggttgt gctccggcat
     7501 agatatggtt gtcagcagct gtaattttga ggaggccgtc aggaattgtg atttgctcat
     7561 aaccggagag ggcaggaccg acagccagac agcaaatggc aaggttgttg cgggacttgc
     7621 caaagtggct gcaaagtatg gtgtgcctgt agtctgtcta tcaggttcat tgatggaagg
     7681 atatcagaaa atatatgaac atggagttga cgctgcattt agcaatataa tttctcctat
     7741 gactttagag gaggccatcc gttcttctcc gcagatgtta acccaggcat cctattcaat
     7801 agcaaggctt atgctgaaaa tatattcaag ggcaaaggca aaataggtta aatataatag
     7861 tactgtatag gcaagtgttg tataatttat ttattgtatg tttaccctct attgacaacg
     7921 tattgtacat tgtcaataga gggtaatgca tattgaaata aatggttata agctataccg
     7981 gatataggct aaaaacaaat atattttcaa atgggagagg ttatatgaca aacagaaaac
     8041 taattctata tattgccgtg agcttggatg gattcattgc agatgagggt gaatcacttg
     8101 aatggctgtt gaaaacagaa ggtgaagggg ataatggtta tggcgggttt tacgagacaa
     8161 ttgacaccgt ccttttaggc agacggacat atgattggat tatgagacat gaaaatggaa
     8221 actttcctta caagggtaaa aaatgttatg ttttttcaaa aagtctgaag ggaaaaaatg
     8281 agtatgtcga gtttacggat gaggaaatac cggccttggt gaaaaacctt aaaggacagg
     8341 aaggcgggga tatctggatt gttggcggag gggagcttct ttactgcttc ataaaggaaa
     8401 gattggtaga cagatttatt ataactgttg ccccggcact gattggcaga ggaattccgt
     8461 tattcaagga aaacgatatt gaaatggatc tggagctcaa gagtgtaaga cggtttaatc
     8521 aatttgcaga acttcaatat gattataaag gcaggcctgt gctttaatac aataaaactt
     8581 aaagaaacta atgttcagct gattccggca ttaaaagcag aaatttacag gaaaagaaac
     8641 ttgaggaaga acttaaaggc ggtgtggatt ctttttttga aaaagggcag aatggtattt
     8701 caaaaaatct gtttgtgacc gaaaaggaag gcaaaaaata cgttgtccaa ttcaccaggg
     8761 atgaggtggg tagaattacc ggaaaagtaa tactgataca aaaagataat tagttaattt
     8821 ctgacggcct gcgattttta aacaagtaaa aattgcaggc cgtttggcag caataaaata
     8881 aatttcaaag tttaattgcc tgatatattt tagtatgcta tagttcattt atattgatac
     8941 tcttaacctg aatatatgag gtgtaaacat gggaaaacag gcactatata atgtaagaac
     9001 tgtggtaaat ttgaaagata tgttaaatca aagcactttt ctgtatggaa acaaggctgc
     9061 gtttattgta aataacagag gggttaatga gaatatcagc tattcccggt ttaaaaccga
     9121 tgttgacgca ttgggtactg cattgctgga gcttggtctc aaggacaaat gcatagcggt
     9181 tattggagaa aacaggtatg aatggtgtgt gtcatatctg gctgttacaa atggaaccgg
     9241 tattgtcgtt ccaatagaca gagagctgca cgtttctgaa ataaataata ttctcggcag
     9301 atgtaatgcc gatgccatca tatactccgg caagcataac gacagcatga aaaagctttc
     9361 aaccacggta ccgtctgtaa aatattttat aaacatggat gaaagccagg acagtgattt
     9421 ttatttgtcc tttaaaagtc ttgttgagag gggaaaagaa cttttagctt caggcaatct
     9481 tgattatgtt gactcggaaa tagacatgga tgccctggca gtgctgctgt tcacctccgg
     9541 gaccaccgga cttgccaagg gagtgatgct gagtcacaga aatatttgtt caaatgtggt
     9601 ttcagtacgt tcaaccgttc tggttgatac aaatgatact tctttgtcca ttcttcccat
     9661 gcatcacacc tatgaatgca ctatcgggtt tctggccttt atttattcgg gagccacaat
     9721 atccttcaat gaaggtttaa agcatatagc caggaatttg aaggaaatga agcctacagt
     9781 tcttgtagtc gtgcccttga tactggaaaa tctctataag aagatatgga cccaggctgg
     9841 aaaacaaaaa ttcggcaggt tgaagctcaa gctggcttta attataacag ccatattaaa
     9901 tcatctcttc cgtattgaca ttgccaatag ggtattcaag caggtgcatg acaacgtagg
     9961 aggaaggctg aggctcatat tgaccggtgc cgcggcaata gacccctctg tttccaaagg
    10021 attcagacgt atgggtataa aggttttaca ggggtatggt ctgaccgaat gtgctcctct
    10081 ggtcacggga aacagggatc atgagtacag ggacagcagt gtgggtaaag ccttgccggg
    10141 tgtggaagtt aaaataaaca atcctgatga aaatggtgtg ggtgaaatcc ttgtaaaagg
    10201 tgaaaatgtt atgctgggct attacaagga tgaggaagaa accggcagaa atcttattaa
    10261 tggctggttc cataccggtg atctcggaat ggtggacaag tccggttatg tatatataac
    10321 cggaagaagt aaaaatatca ttattacaaa taacggtaaa aatgtatacc cagaggaatt
    10381 ggaagcttcc ataaacaaga atccctgtgt acaggaatcc cttgtttcgg gtgaaattga
    10441 ccggacaaca ggagaaacgc atattcatgc gcatatattg ccaaaccttg aatatataaa
    10501 ggaaaagttc aagggagtaa gtctgacgaa ggatgaactg ctgaagctgt ttaatgagat
    10561 tgtaaaaagt ataaataaag atctgcccat atacaggcgc ataaggaaat ttacgctgcg
    10621 tgaaagtgaa tttattaaaa ccacaacaaa aaaaataaag cgttattgtc cagaaaatgt
    10681 tgagggttaa tatttgccgt actctttcga aggtggttaa atactttgga atctttaata
    10741 aatgtcagca ttttgaagga tttcacaata taacagccgg tagacaggta ttcatcggtt
    10801 gaggttattc ttctatagat ttacaattat aaaatgcata aaaatttata cattatacaa
    10861 aattttattt acacactagt ttatgcaatt ttatattaaa ggccgtgata taattgtttt
    10921 ctaaaaaaga actgatgcgt ctcttctttc ctgcatttgt tgagcagttt ctttccacag
    10981 ctataggggt tgtcaacacc atgatggtaa gcggacttgg agcttttgca gtatcagccg
    11041 tgggtatcgt ggattccatc aactttgtcg caatgaatct gtttctttcg gtagcaacgg
    11101 gagcgacagt agtaattgca cagcatctgg gtgcgggcaa ccaggaaaag gcttcaaata
    11161 cggcagcgca atcaatcgta tcggtttttt tactctctgc tttgacaggc ttgggactct
    11221 ttgttttcgg acagcaaatc attggattca tgttcggagg agccgaaccg gttgtaaaat
    11281 cggcggcctg gacatatctg gtctgctcag caatatcata tcccctgttg ggactattta
    11341 atgtttttac aggtgtattg cgtgccaata ataattttat tgcttcaatg acgtcaatag
    11401 ttatttccaa ccttgtaaat ctcggcgtgg gagccatatg tatcttcaag cttgacctgg
    11461 gagtgctggg cgcaggcctg ggcctgattt cggccagact tgtgggtgcg gtggtattgc
    11521 tcttccattt gctggggagc cccaaaatac atatcaggtc ggcttccttc aaggtatcct
    11581 tcaacataat gaagcctgtt ttatatatag gggttcctgc gggcctggac agtcttgtgt
    11641 ttaacggagg caagctgctg gttcaggcaa ttgtggcgtc ccttggaacg gcttcccttg
    11701 cggccaacag tattgcaggt tcgctgaatt caattataaa cattcccgga ggtgccgttt
    11761 ccatagttgc tgtcagcata ataggctact atgcgggagc aggcgacaag caggaactta
    11821 agaaaatgat caacaggctc acattatatg caatgatttt acttggtggg gtttcactgc
    11881 ttttcctgcc attttcgtcc catatcctca aactttatca gcctgctgat gatgtgttga
    11941 ccatggcact gcacataacc tatctgactc tggcctgcat acctatattc tggcctgccg
    12001 cctttattat accggcttgt ctcagaagta ccggcgatgt tgtgtatgtg actgtggtat
    12061 caatactgag catgtggctt gtaagagttc tgctgggata tctgctggtg aagtacacca
    12121 gcctgggaat tatgggtata tggattgcct ggtgctttga ctgggttaca agaggggtgc
    12181 ctttttacgc cagggtgctc agccggaaat atgagaaata tattccggcc cggactgacc
    12241 agactgtaac cgaataggca ggaacaaaat ttttaatatt tcttttaata tttaatgatt
    12301 gataaatttc atactatgtg gtatactagc tagcggaaaa atacacacgc atcttgaatt
    12361 gttaaagtgt cggtaaaatg ataaaatcgt caatatttaa gttgtacgat aacatgggat
    12421 gcggaggtat taactttaac ggaggtgttt taatatggca gttatttcaa tgaaacaact
    12481 tttggaggca ggtgtccact tcggtcacca aacaagaaga tggaacccga agatggcaga
    12541 atacatcttt acagaacgta atggtattta catcattgac cttcagaaaa cagtaaagaa
    12601 agtggatgac gcatacttct tcataagaga agtggcaatg aacggacagg atgttctctt
    12661 tgtaggaact aaaaagcagg ctcaggattc cattaaggaa gaagccgaca gaagcggaca
    12721 gttctttgtg aacaacagat ggctgggcgg tatgctcacc aacttcaaaa ctattcgcaa
    12781 gagaatagac agattgaacc aattgaatgc tatggaagca gacggaactt ttgaagttct
    12841 tcccaagaaa gaagttatca agcttaagaa ggaaatggaa gatctcgaaa agaaccttgg
    12901 cggaatcaag aacatgaaga agattccggg agcaatgttc gttgttgacc cacgcaagga
    12961 aagaaatgct atccttgaag ccaaaaagct cggtattccg gttgtagcca tagttgatac
    13021 aaactgtgat cctgatgagg ttgatttcgt aattccgggt aatgacgatg ctataagagc
    13081 tgttaagctc attgcagcaa aaatagccga tgctattatc gaaggccgtc agggtgaaca
    13141 actttcacct gaggctgttg aaacagttga agctgtggaa gttgtagaag ctgctgctga
    13201 ataatttagt atgaaatgat atattgccgg attgtgttta atacacaatc tggtaattag
    13261 tcttaatcga taatgaactt aatattttat tcgggtatat tattctatta ctaaataatt
    13321 aatggcacag gcgataaatt attgtttatc ccatttatga catggggtaa ttcaattggc
    13381 ctatgtcgga aatggagata aaaatgatta ctgcagaaat ggtaagacag ctccgtgaaa
    13441 gaaccggagc cggaatgatg gactgcaaaa aggcactcac agaaacaaac ggcgatgccg
    13501 ataaggcagt tgagtatttg agagaaaagg gtatagccaa agccgccagc aaagcgggaa
    13561 gaattgctgc tgagggcttg gttgaatctt atatacatgg cggcggaaga attggtgttc
    13621 tcgttgaagt aaacattgaa accgactttg ctgcaaagaa tgaagaattc aaacaattgg
    13681 tcaaggatat tgcaatgcag atagctgcaa gcaaacctga attcgtaaga agagaagaag
    13741 tacctgcttc ggtattggaa gctgaaaagg aaattttaag agcacaggcc aggaacgaag
    13801 gaaagcctga aaaaatcatt gataaaatgg ttgaaggcag aatcgataaa tactacggtg
    13861 aaaaatgttt gatggaacag gccttcatta aggatcctga tattacagtc gatcagctga
    13921 tcaaggaaaa aatagctcat attggtgaaa atatcactgt tagaagattt gttagatttg
    13981 aaagaggcga aggtatagaa aagaaagaag aaaacttcgc tgatgaagta atgaaacaaa
    14041 taggcggtta ataataaagg gggctgttgc aaaacaaaat aaactgtttg ttttgtggca
    14101 gccccttttg gaacatatgc ttgtatgttc cttttattag ggcctttttt ggaaaaataa
    14161 tatatttatc taacggagga aaaccatgtc ggaaataaaa tatcgaagaa taatgttgaa
    14221 gatcagtgga gaggctttat ccggtgaaaa aggcaatgga attgatacca acactgttaa
    14281 cgaaatatgc gacagaattc ttgcagtaca caatctggga gtggaaattg ccatcgtagt
    14341 gggcggaggt aacttctgga gaggcagaag cggtaagggc atggacagga ccacagcgga
    14401 ccacatgggg atgcttgcaa cagttataaa ttcactgggg ctccaggatg cacttgagtc
    14461 gaggggaatt caggtgagag tccagactgc cattgaaatg agacagatag ccgaacccta
    14521 tgtaagaaga aaggccgtaa gacatctgga aaagaagaga atcgtaatat ttgcctgcgg
    14581 catgggtaat ccttattttt caactgatac ggcagcagct ctcagagcgg ctgaaattga
    14641 tgctcaagcc atacttatgg ctaaaaatgt tgatgggata tatgattccg atccttcaaa
    14701 aaatcccgat gccgttaaat acaacaaact cagctatcag gaatatctca ataaaaatct
    14761 gtgtgccatt gatttgacag cagcttcctt ctgtaaggat aacggaatac ctacgcttgt
    14821 attcggattg aatgatcctg ataatatcat cagggcggtc aagggtgaag agattggtac
    14881 tacaatatat tgaaatcctt tgtgattaat tgtattatat atagggaatg tataaattat
    14941 tcctgggaat attcaggaag ataatcttta tttattggca acaaattttt ttaggaggag
    15001 tattatggat aaagagcttt ataaacctat tgaagaaaag atgaagaaga ccataaatgt
    15061 attaaaggac aatcttgcag gcatccgagc aggaagagca aatccccaga tacttgataa
    15121 aattaccatt gattattacg gcgcgccaac acctattcaa caggttgcaa ctgtgtcagt
    15181 accggaagca agagttattc tgatacagcc atgggaagca aagctcctta aagatataga
    15241 gaaggaaatt caaaaatctg atatcggcat taatcccaat aatgacggaa agatgctccg
    15301 tcttgttttc ccggccctca cagaggagag gcgtaaggaa ttaaccaaat cggttaaaaa
    15361 ggaaggcgaa gaagccaagg ttgccatcag agctataaga agagattcca tagagcatat
    15421 gaaggccaag aagaagagca gtgaaattac cgaggatgat ttaaaggatg ctgaaaagga
    15481 cattcaaaat ctcaccgata aatttattgc cgaaatagat cgtatagtag aagcaaaaga
    15541 taaggaaata atggaagtat gaaccggcta atagggtata cgcttggaga tgcctttaag
    15601 ctggcccggg aggaaggctt tgaaatcggg gaaattacaa ttacatctcc tcccaaaatg
    15661 gagattttgg aatacgatga ttctttccgg gtacttcgtg tcaatacttc ggaaaataaa
    15721 ttgaatattc tggtatgcaa acccctctaa atgaggggtt attttaaaag cggccgggat
    15781 atggacagag tttacataca ggtattttaa atactatttg ttttattgtg cgtactttgg
    15841 tacgcctgtg tacgaagatg gaggtcggtg tgggtatttg ggacagtgtt gcccggttgt
    15901 tgggacgaaa aaaagacgtt aagcaggagt ttgcttcaat tccgaagcac atagccatta
    15961 tccccgacgg aaacggaaga tgggcaaaga aaaggggtct gcccagaaat gtaggtcaca
    16021 gggaagggtc catggctttg aaaaaggttg tcatatattg ttcagaggca ggcgtaaaat
    16081 atctgacggt atacgctttt tccacagaga actggaagcg tcccaaaagt gaagtggatg
    16141 ccctcatgag tctgcttgtg gagttcctgc ggaatgcgga aaaggaactt gacggcagca
    16201 atgtaaaaat aaaggtaata ggagatgtaa aaggtcttcc ggaagaactt cagaaggaaa
    16261 ttatcagagt ggaaaagctg accggcatta ataacggcct taatttaaat atttgcctta
    16321 attatggagg aaggcttgaa ctgctgcatg cagtcaagga aattgcagtc aaggttaaat
    16381 cgggtaattt aaaaatagat gaaatagatg aaaaacaatt tgaaagctgc ctgtatactg
    16441 ccggaattcc agaaccggat ctgcttatca gaaccagcgg tgaacagagg ataagcaatt
    16501 ttcttttatg gcagtgtgca tatactgaat tctggtttat aaatgaatta tggcctgatg
    16561 tgaacggaag ccatattgca gaagcaataa gagcttatga aaaaagaaac agaagatttg
    16621 gcggactgga gcaataacgc cggatttaat aacccaaacg gtcctgacgt attaaagccg
    16681 ggtgctgttg gaatcatgga ggcataatgt taaaaacaag agttatcagt gcattggtag
    16741 gacttatcct gctcatagca gttttatatc tgggatctat cgtattggga gttgtagtaa
    16801 gtataattgc agcaataggg ttgtatgagt tttacaattc tgcagccaag ctgaaaaata
    16861 ttcatcccat aaagccggtg ggctacctgt caataattcc gcttttattg ctggggctgg
    16921 aggaaacagg ttggtacaga cttgatctgg gaattttgac cggaatttct gtttgtgttg
    16981 ttatattttt aagtatggct tttattgttt tcgggcataa aagatataat ataatagatg
    17041 cctgtgtaac tgcctttggt attgcctatg tgcctttcct tatgagcttt ttgattctga
    17101 taaggaagat ggattttgga attctgctga tttggctcat attcatagga gcatggggca
    17161 ccgacaccat ggcatatacc tttggaagat tattcgggaa aagaaagatc gtacccgaga
    17221 taagtaagaa taagaccatg gcaggtgcaa tcggaggcat tctaggctgt gtggcgctga
    17281 tgttcgtctt cggacttata tccaggtcct tttttggact tgagctttcc acggctgcac
    17341 ttgtattgct gggactgttc tgcggtgtaa tttcccagat cggtgactgg tcggcatctg
    17401 ctgtcaagag atatgtgaac gtgaaggatt acggcagtat catgccaggt cacggcggag
    17461 ttctggacag gtttgacagt atattgttcg ttgctccggt agtttattat gtaatagtag
    17521 tctgtaacat ctaaattcat acattgccga cggttaaatt tccccagaac tgcgttgtcg
    17581 aaaagcactg cttcgcagta cttcgttgga ataaagcgat tattccgccc ttctccgcct
    17641 tgtcctgaaa aaattttcct cgccggacaa tatacgtttt agatgttaca gactaccagt
    17701 acttttcttt aaaggctgaa agacctaata ttgttgttcc attggggatg tggaggttaa
    17761 atggcaaaga taatttcaat tataggatcg accggttcta taggtgtaca gacattggat
    17821 gttgccagaa atcttggaat aaaagttgca gcaatgtctg caaattcaaa tatagattta
    17881 cttgaaaagc aggttcatga gttcaaaccc cggctggttt cggttgggag cagggagctt
    17941 gcctcagaac tgaaagccag gctggcgggt atgaaggtgc aggttttgtc gggccttgaa
    18001 ggaatgcttg gcgtggtgga agtacaggag gcggatactg tggtgacgtc ggtggttggc
    18061 actgccggcc ttattccgac tatgcatgcg ataaaaaaca gaaaaaatat cgcattggcc
    18121 aacaaggaaa cccttgtaac ggccggccaa ttggttatgg aggaggctaa aaagcaggga
    18181 gtggcaatat tccctgtgga cagcgagcac tcggctattt accagtgtct tatgggcaac
    18241 agcgacagac aggttgagaa aataatcatt actgcttcgg gcgggccttt cagaggcaga
    18301 acgcttgagg agcttaggga tattacccct gcacaggccc tgaaacatcc caattggagc
    18361 atggggagca aaataaccgt tgactctgcg acactaatga acaaagggct ggaagtaata
    18421 gaagcaaaat ggctttttgg cagggaactg gataaaatac aggtgctggt gcaccctcag
    18481 agcatcatac actccatggt tgaatatgtt gacggatcgg ttatggcgca gctgggttca
    18541 cccgatatgc gcatacctat tcagctggct ctcacatatc cagacaggtg cgggaataat
    18601 ttctcaaggc tggatttctt gaaatgttcc cagctaacct ttgaagagcc tgatacaaaa
    18661 accttcaggt gtctccagct ggcgtatgat gccatgtcaa cgggcgggac aatgactgcc
    18721 gcgatgaatg cggccaatga agcagccgtg tcggcatttt taaacaatag aatagctttt
    18781 acagctattc cggaaataat tgaaaagata atgatgttac ataaggtgaa tatttgtcca
    18841 ggcctggatg atataataga agtagacaac tgggccagaa cacaggctga aaaagcagta
    18901 aacggttaag gaaacaagtc ttgaaaaaca aaacaaacgg aggaatctat gggaattgta
    18961 ctggcaatat tagctctgag ctttttgata ataattcatg aacttggcca ttttatggtg
    19021 gcaaaggctt tcaaggtaag ggtaaatgag ttttcgcttt ttatggggcc caagctgttt
    19081 tcctttcaga aaggtgaaac cctttattca ttaaggctta taccccttgg cggctacgtc
    19141 aagatggagg gcgaggagga agcttcggag gatgacaggg cttataataa aaagcctata
    19201 ggcgtgagag ctgctattat tgctgcaggg ccgttgatga atatccttac ggcacttgta
    19261 tttgccttta taataatatc ccagacaggt tattttacca cacagataaa ggatattgta
    19321 cccggttcgg cggcagaaaa gtatgacctt cgggttggag acaaacttca gaagtataac
    19381 ggaaaaaccc tttttaatgt aaatgacctg ggaatatttt cctacccgct tacaaacgaa
    19441 agtataacac tgcaatatga gagaaatggc gtatcaaaga cagttgagct gacacccgaa
    19501 agagaaaatt ttatacttgg tttcacaccc ctgcaggatg aacttgaagg gcccgattca
    19561 aatgtagtta aagctgtttc ggacaattct cctgcaataa aggccgggct caaggtaaat
    19621 gacaggatag ttgaaattaa cggagccgat ataaggacaa gaaaagacat acgtgatata
    19681 ctgcagcaga atcaggataa aaatgtgaat atacttgttg agagggcagg agagcttcag
    19741 aaattaaagc cggtagttcc cctgaaaagc aaaaatcccg aatattacgc tatcggtata
    19801 cttgattttg tccatgaaaa gggcagtatc ggcagtacaa taaaagaagc tgcgaaatac
    19861 aacatattca tttccaggtc aatatattat tcccttggct ggttgtttac agggacggtt
    19921 cctgcaagcg aactcatggg tccggtgggt attaccacta caatcagcaa tgaggtggca
    19981 gaaagccagt cgctcaaaga aaccgtaatc agacttttgt ctattacaac catgattagt
    20041 ataaacctgg ggctggtaaa tcttattccg ttccccgctc tcgacggcag caagcttgta
    20101 ctgctgctca ttgaaggaat cagaaagaag cctctcaatc ccgaaaagga agcgttaatc
    20161 accatggttg gtatggtaat tctgataatg ctcatgttat atgctacctt caacgatata
    20221 ctgaggatcg gaaaaggtta gtgcagacca ttggagacca ataattacag gaaggttgac
    20281 ggctgtggag aattatatac agagaaaaca gacaaagaaa ataaaagtgg gagatatctt
    20341 cttaggagga gattctccta tttctgttca atccatgaca aataccgata caagagatgt
    20401 aaagtccacg gtggaacaga taaaaagact ggaggaggaa ggctgcagca ttgtcagggt
    20461 tgcagttcca gacagccagt cggcagaggc tgtaaaagag ataaaaaaag ccatctcaat
    20521 accgctggtt gccgatattc actttgatta cagactggct ctggagtgca tgaaaaacgg
    20581 tgtggacaag atccgtctga atccgggcaa tataggcggg caggacaggg taaaaacagt
    20641 ggcggatatg gcaaaggaac gtcagatacc catacggatc ggagtaaact
//
