LOCUS       c00022_NZ_JHYD..       20624 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHYD01000032.1 Ruminiclostridium cellobioparum DSM 1351 = ATCC
            15832 T344DRAFT_scaffold00022.22_C, whole genome shotgun sequence.
ACCESSION   NZ_JHYD01000032
VERSION     NZ_JHYD01000032
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:33:25
            Original ID  :: NZ_JHYD01000032.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 67933
            Orig. end    :: 88557
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20624
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[77933:78557](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10624
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20624
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20624
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(237..944)
                     /locus_tag="ctg22_63"
                     /transl_table=11
                     /translation="LIDTEIKSNLDNIFKRVGAAAEKSGRSVEDIRVIAVTKTVEADRI
                     KNVYEYGILDMGENRVQELTEKYDRLPSDCKWHLIGHLQTNKVKYIIDKVEMIHSVDSM
                     ELAKEINSRAAKHGRKIDILLQVNVSGEDTKFGISPGDVDEYVGIISRMENISLRGLMT
                     IAPFTQDPQVIRPVFRNLYNIYIDIKHKNIDNVNMDYLSMGMSNDFEIAIEEGANIVRI
                     GTGIFGKRDYTKK"
     PFAM_domain     complement(255..917)
                     /aSDomain="Ala_racemase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01168.22"
                     /description="Alanine racemase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_63_0001"
                     /evalue="2.30E-21"
                     /label="ctg22_63"
                     /locus_tag="ctg22_63"
                     /protein_end="230"
                     /protein_start="9"
                     /score="76.5"
                     /tool="antismash"
                     /translation="LDNIFKRVGAAAEKSGRSVEDIRVIAVTKTVEADRIKNVYEYGIL
                     DMGENRVQELTEKYDRLPSDCKWHLIGHLQTNKVKYIIDKVEMIHSVDSMELAKEINSR
                     AAKHGRKIDILLQVNVSGEDTKFGISPGDVDEYVGIISRMENISLRGLMTIAPFTQDPQ
                     VIRPVFRNLYNIYIDIKHKNIDNVNMDYLSMGMSNDFEIAIEEGANIVRIGTGIFGKR"
     aSDomain        complement(255..929)
                     /aSDomain="TIGR00044"
                     /aSTool="tigrfam"
                     /description="TIGR00044: pyridoxal phosphate enzyme, YggS
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_63_0001"
                     /evalue="1.10E-58"
                     /identifier="TIGR00044"
                     /label="ctg22_63"
                     /locus_tag="ctg22_63"
                     /protein_end="230"
                     /protein_start="5"
                     /score="196.5"
                     /tool="antismash"
                     /translation="IKSNLDNIFKRVGAAAEKSGRSVEDIRVIAVTKTVEADRIKNVYE
                     YGILDMGENRVQELTEKYDRLPSDCKWHLIGHLQTNKVKYIIDKVEMIHSVDSMELAKE
                     INSRAAKHGRKIDILLQVNVSGEDTKFGISPGDVDEYVGIISRMENISLRGLMTIAPFT
                     QDPQVIRPVFRNLYNIYIDIKHKNIDNVNMDYLSMGMSNDFEIAIEEGANIVRIGTGIF
                     GKR"
     CDS             complement(937..2193)
                     /locus_tag="ctg22_64"
                     /transl_table=11
                     /translation="MSVFKKQSVRIGTLIAGVFLLIYLPALLFIIYGNGVETDILKIGK
                     IEDTQNIDGVFIRNEELILSPETGNCVMDAVDGEKVPAFYRIASVVKNVPVSTYEELKT
                     KEMEIERAQKAQKENINMFSSDIKKLDSEIIEEVKNLAQQSIRGSLVESYNSLSSIDRI
                     VYRKSDIFGDSSKSAAYINKLKNEKAAIQGKLNNNIKEIRTKSSGLISYAIDGYESILT
                     PETIRNITPKELEKITTRETNRDFNVIDAAKGKPVAKLVKDLDSYMVTAVDEKYCKSLQ
                     LDKTVTLRINDTGLNIEAKIVYSSDLIDGKRIIAFKFDAGLNETVGLRRVNADIILSSY
                     TGLKVPYSSLQNIDTKNKTALITVVKGHTAAIKKVRIVGMNESAVIIDNLEGENTNTIA
                     LYNTYILNPKNIQEGQTVD"
     PFAM_domain     complement(943..2154)
                     /aSDomain="HlyD_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12700.9"
                     /description="HlyD family secretion protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_64_0002"
                     /evalue="6.50E-55"
                     /label="ctg22_64"
                     /locus_tag="ctg22_64"
                     /protein_end="417"
                     /protein_start="13"
                     /score="186.7"
                     /tool="antismash"
                     /translation="LIAGVFLLIYLPALLFIIYGNGVETDILKIGKIEDTQNIDGVFIR
                     NEELILSPETGNCVMDAVDGEKVPAFYRIASVVKNVPVSTYEELKTKEMEIERAQKAQK
                     ENINMFSSDIKKLDSEIIEEVKNLAQQSIRGSLVESYNSLSSIDRIVYRKSDIFGDSSK
                     SAAYINKLKNEKAAIQGKLNNNIKEIRTKSSGLISYAIDGYESILTPETIRNITPKELE
                     KITTRETNRDFNVIDAAKGKPVAKLVKDLDSYMVTAVDEKYCKSLQLDKTVTLRINDTG
                     LNIEAKIVYSSDLIDGKRIIAFKFDAGLNETVGLRRVNADIILSSYTGLKVPYSSLQNI
                     DTKNKTALITVVKGHTAAIKKVRIVGMNESAVIIDNLEGENTNTIALYNTYILNPKNIQ
                     EGQTV"
     CDS             complement(2217..3503)
                     /locus_tag="ctg22_65"
                     /transl_table=11
                     /translation="MDFKIREYLKQYFEIEDRVIELAEQAEKDAQKVFERIENTKQINQ
                     LKVIKAMQDNKLSDSHFNGTTGYGYDDRGREVLDSVYANIFCAEDALVRHQIVSGTQAL
                     ALCLFGNLRPGDQLVAVTGKPYDTLEEVIGIRGENCGSLKEFGVNYRQVELRPDGKPDL
                     EQIRRVVTPSTKMAMLQRSRGYSWRDALCIEDIKSVISTVKSINSSIIVMVDNCYGEFV
                     EEVEPIEAGADIIAGSLIKNPGGGLALTGGYIAGRKELVEQAAFRLTSPGLGKEVGASL
                     GNNRLMFQGLFMAPHVVAESLKGAVFCAALMERAGFETLPSVDAKRSDIIQAVKFDNEQ
                     SLIAFCQGIQKGSPVDSYVTPQPWEMPGYDSPVIMAAGAFVQGSSIELSADAPIKSPYI
                     AYMQGGLVYEHVKLGNIIALQKLFNSRDK"
     PFAM_domain     complement(2238..3446)
                     /aSDomain="Met_gamma_lyase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06838.13"
                     /description="Methionine gamma-lyase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_65_0003"
                     /evalue="6.80E-193"
                     /label="ctg22_65"
                     /locus_tag="ctg22_65"
                     /protein_end="422"
                     /protein_start="19"
                     /score="640.8"
                     /tool="antismash"
                     /translation="IELAEQAEKDAQKVFERIENTKQINQLKVIKAMQDNKLSDSHFNG
                     TTGYGYDDRGREVLDSVYANIFCAEDALVRHQIVSGTQALALCLFGNLRPGDQLVAVTG
                     KPYDTLEEVIGIRGENCGSLKEFGVNYRQVELRPDGKPDLEQIRRVVTPSTKMAMLQRS
                     RGYSWRDALCIEDIKSVISTVKSINSSIIVMVDNCYGEFVEEVEPIEAGADIIAGSLIK
                     NPGGGLALTGGYIAGRKELVEQAAFRLTSPGLGKEVGASLGNNRLMFQGLFMAPHVVAE
                     SLKGAVFCAALMERAGFETLPSVDAKRSDIIQAVKFDNEQSLIAFCQGIQKGSPVDSYV
                     TPQPWEMPGYDSPVIMAAGAFVQGSSIELSADAPIKSPYIAYMQGGLVYEHVKLGNIIA
                     LQKL"
     CDS             complement(3727..4344)
                     /locus_tag="ctg22_66"
                     /transl_table=11
                     /translation="MKWLASFKLVVLVLSILILLPGCSTINENNSNEPYGTHGNQITST
                     STGDEVTLEKTESKLFADISKYTIENPKAYSNDEFKLSVDYPAEWEVSIDGKSSPDLPD
                     GDPQRGISIYVESNKNDLIYVYHQFGHIGLLTDGFTSENFTTTAGVKGKILYQKSQENI
                     KIYLVLGDAFNGAIIKMSETSFQKNKGQILGILKSIKIAEFE"
     CDS             complement(4457..5527)
                     /locus_tag="ctg22_67"
                     /transl_table=11
                     /translation="MKRFKSFLCILIVLCFSISVFGIYAENDDPAVKPDLFIGTEKVCV
                     GLETSASNVVIESNGYSEFVDCYATLDDNTVMNVNYDAKWETDNQNIAVAFEGRILAKG
                     KGKTRIKVSYEGFEKYIDVEILKEIDLIKEEKALNEIFKSRKSNDDMLGTLSLTNSERQ
                     EIRDKAMAMIAYIWRPAKDLTGWKDLYTFEKDTTCIGIPYSQTPNQVDEAGFKSAQSKS
                     DFYTSITSPNIMPRYGNDCSGFTSFSWGISRQTTLSFYNGIKKGTYPKVGSYNADTPTS
                     PSASELKNSYKLLQTGDAVVYRTSDNTGGHVFVIAVNFTTDSKVQCFEQTDPYCDITYW
                     TYDQLANRKYMPFAKK"
     CDS             5982..6887
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1279:pseudouridine synthase (Score: 219.8; E-value:
                     8.1e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_68"
                     /transl_table=11
                     /translation="MILEHKADISDAGRPLKYILKGRLQISERLVKKLKFQNKIYVNSE
                     AVHVNFIIKENDQIRVELELEEYCEYIEPQDIPIDIIYEDNCLLVLNKQSGTVVHPTSS
                     HPDSTIANGIVYYLKGKGISKKVRPVSRLDRETSGIIIFAKNQFAQEALIRQMKAKIFE
                     KEYLGIVQGIPLSNAGTIDLPIDRKPGSIMLRHVSETGAPSVTHYAVMESFPLHNAALL
                     KFKLETGRTHQIRVHCQAMGFPIYGDTLYSENTGLLISRQALHSHITKIVHPETHKEVI
                     FNAELPQDMKAVLEIMRNSL"
     aSDomain        6027..6875
                     /aSDomain="TIGR00005"
                     /aSTool="tigrfam"
                     /description="rluA_subfam: pseudouridine synthase, RluA
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_68_0002"
                     /evalue="1.20E-73"
                     /identifier="TIGR00005"
                     /label="ctg22_68"
                     /locus_tag="ctg22_68"
                     /protein_end="298"
                     /protein_start="15"
                     /score="246.0"
                     /tool="antismash"
                     /translation="LKYILKGRLQISERLVKKLKFQNKIYVNSEAVHVNFIIKENDQIR
                     VELELEEYCEYIEPQDIPIDIIYEDNCLLVLNKQSGTVVHPTSSHPDSTIANGIVYYLK
                     GKGISKKVRPVSRLDRETSGIIIFAKNQFAQEALIRQMKAKIFEKEYLGIVQGIPLSNA
                     GTIDLPIDRKPGSIMLRHVSETGAPSVTHYAVMESFPLHNAALLKFKLETGRTHQIRVH
                     CQAMGFPIYGDTLYSENTGLLISRQALHSHITKIVHPETHKEVIFNAELPQDMKAVLEI
                     MR"
     PFAM_domain     6243..6701
                     /aSDomain="PseudoU_synth_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00849.24"
                     /description="RNA pseudouridylate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_68_0004"
                     /evalue="5.30E-30"
                     /label="ctg22_68"
                     /locus_tag="ctg22_68"
                     /protein_end="240"
                     /protein_start="87"
                     /score="104.7"
                     /tool="antismash"
                     /translation="LLVLNKQSGTVVHPTSSHPDSTIANGIVYYLKGKGISKKVRPVSR
                     LDRETSGIIIFAKNQFAQEALIRQMKAKIFEKEYLGIVQGIPLSNAGTIDLPIDRKPGS
                     IMLRHVSETGAPSVTHYAVMESFPLHNAALLKFKLETGRTHQIRVHCQA"
     CDS             6999..7610
                     /locus_tag="ctg22_69"
                     /transl_table=11
                     /translation="MDILKDRYSITELSECLNITDHALRFYEKEFGLKIPKDSRGRRFY
                     TTELANVMYQIKDMRDQGLELKAIRKILEDEHIIKVNPPGTALNSSVQLNEAQLPAIMG
                     HAASQLSSTELTAIIDALNNMKEQVFNNISTELLSTREQISKEIHKSKLELGACVENSS
                     RKLEIKLDRHFQEVDRNITSWRERKSTSLGGRLKKLIGKA"
     PFAM_domain     7020..7223
                     /aSDomain="MerR_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13411.8"
                     /description="MerR HTH family regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_69_0005"
                     /evalue="2.10E-19"
                     /label="ctg22_69"
                     /locus_tag="ctg22_69"
                     /protein_end="75"
                     /protein_start="7"
                     /score="69.5"
                     /tool="antismash"
                     /translation="YSITELSECLNITDHALRFYEKEFGLKIPKDSRGRRFYTTELANV
                     MYQIKDMRDQGLELKAIRKILED"
     CDS             complement(7888..8790)
                     /locus_tag="ctg22_70"
                     /transl_table=11
                     /translation="MKKKYLSIVAVLVLLSFTSGAFAATNVTAIKAFLNKGIVINIDNA
                     KFQPKNDKKEILYPIVYNGKTYVPIKEFAEDLGAAVKYDSKGDGTYNVTSTAGEDGIPT
                     QDGNSSSGSKTSGSTTSADGSLSSPVPINEKFTWSSTSQLTEKDNKISGTYSCTVKKVT
                     PITKDEIAALGIKNSSNDSRIEYVMVNILWEVKDAKVLINNTGMKSSLSTYWTPNIWGV
                     ETADKSWIIGTRDYGFEGSLSSAVSKAGTARLDVGMTESYSAEGKAIIPVYKNDTNYLV
                     LRKSGEKDAEKSKIHFKLK"
     CDS             complement(9275..9673)
                     /locus_tag="ctg22_71"
                     /transl_table=11
                     /translation="MYCRNCGNVMNDQAAICVACGVPVGKGNNYCPLCGDITDSMAQVC
                     MKCGVNFNAYGQQKSKLAAGLFGIFLGMFGVHRFYLGYIGLGLAQLLLTLLSCFIFSPF
                     IYIWGLIEGILILAGTINKDAKGFPLKD"
     PFAM_domain     complement(9332..9505)
                     /aSDomain="TM2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05154.18"
                     /description="TM2 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_71_0007"
                     /evalue="6.60E-16"
                     /label="ctg22_71"
                     /locus_tag="ctg22_71"
                     /protein_end="114"
                     /protein_start="56"
                     /score="58.5"
                     /tool="antismash"
                     /translation="QQKSKLAAGLFGIFLGMFGVHRFYLGYIGLGLAQLLLTLLSCFIF
                     SPFIYIWGLIEGI"
     PFAM_domain     complement(9527..9667)
                     /aSDomain="DZR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12773.9"
                     /description="Double zinc ribbon"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_71_0006"
                     /evalue="2.30E-06"
                     /label="ctg22_71"
                     /locus_tag="ctg22_71"
                     /protein_end="49"
                     /protein_start="2"
                     /score="27.6"
                     /tool="antismash"
                     /translation="CRNCGNVMNDQAAICVACGVPVGKGNNYCPLCGDITDSMAQVCMK
                     CG"
     CDS             10001..10624
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_72"
                     /sec_met_domain="AgrB (E-value: 4.4e-40, bitscore: 129.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFVQKWSYACAKHLAYVLNENHNKRSVYYYGFYVLFGTLVKGII
                     LISVSLLLGIFIPALVTVVVLASLRLFAGGYHFDTYGKCLFVSMALTIMTALISQYTHI
                     YWSMAAVAIFLFIVSAFSLHMLIKYAPKDTPTKPITDPAAIIKFKRLSIVYLGILLVLC
                     CILLFFNLKMYVIAICFGVLLEIFSITPAGHGFFNFIKSGLNNV"
     PFAM_domain     10055..10564
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_72_0008"
                     /evalue="8.60E-38"
                     /label="ctg22_72"
                     /locus_tag="ctg22_72"
                     /protein_end="188"
                     /protein_start="18"
                     /score="129.6"
                     /tool="antismash"
                     /translation="LNENHNKRSVYYYGFYVLFGTLVKGIILISVSLLLGIFIPALVTV
                     VVLASLRLFAGGYHFDTYGKCLFVSMALTIMTALISQYTHIYWSMAAVAIFLFIVSAFS
                     LHMLIKYAPKDTPTKPITDPAAIIKFKRLSIVYLGILLVLCCILLFFNLKMYVIAICFG
                     VLLEIFS"
     CDS             10926..11249
                     /locus_tag="ctg22_73"
                     /transl_table=11
                     /translation="MDDIRNNLLIYFMTSLPARFLQLSLITYLISRKRTLVKGWLIKAI
                     LSSPVVAVILCLLVLANILSLQMFGSAIILDKLLISIPRTSQIFIITGVALFPILNISG
                     IPW"
     CDS             11243..11416
                     /locus_tag="ctg22_74"
                     /transl_table=11
                     /translation="MVTKDKKLASEKLNKLLKDIELYADHSNFDNVRWKLNDIGMGIED
                     VAKNLYKEHGTQ"
     CDS             12295..12441
                     /locus_tag="ctg22_75"
                     /transl_table=11
                     /translation="MLVDEINNLREVLNEQVENCSLDNESLLALSQDLDKLIVEYYKDV
                     LMV"
     PFAM_domain     12298..12423
                     /aSDomain="SpoOE-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09388.12"
                     /description="Spo0E like sporulation regulatory protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_75_0009"
                     /evalue="3.70E-11"
                     /label="ctg22_75"
                     /locus_tag="ctg22_75"
                     /protein_end="43"
                     /protein_start="1"
                     /score="42.8"
                     /tool="antismash"
                     /translation="LVDEINNLREVLNEQVENCSLDNESLLALSQDLDKLIVEYYK"
     CDS             12557..13651
                     /locus_tag="ctg22_76"
                     /transl_table=11
                     /translation="MKLGIVGLPNVGKSTLFNAITKAGAESANYPFCTIEPNVGIVAVP
                     DERLDKLAEMYNPEKITPTVIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHVVRC
                     FEDGNIVHVDGSIGPKRDVETINLELIFADLEMLERRIDRTRKNLKSGDKKFQIEMELY
                     ESIKAHLESGKPARSMTFDSEQQQIVDQLFLITLKPVLYAGNVSENDLSSLEANKFLAE
                     LKEIAADEGSEVMVICAKVEEEIAQLADEEKADFLEAMGLDESGLDKLIKASYKILGLI
                     SYLTAGPQEVRAWTIIKGTKAPQAAGKIHSDFERGFIRAEIVAYNDLMACGTYNAAKEK
                     GLVRSEGKEYVMQDGDVTLFRFNV"
     aSDomain        12560..13648
                     /aSDomain="TIGR00092"
                     /aSTool="tigrfam"
                     /description="TIGR00092: GTP-binding protein YchF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_76_0003"
                     /evalue="1.50E-156"
                     /identifier="TIGR00092"
                     /label="ctg22_76"
                     /locus_tag="ctg22_76"
                     /protein_end="364"
                     /protein_start="1"
                     /score="519.1"
                     /tool="antismash"
                     /translation="KLGIVGLPNVGKSTLFNAITKAGAESANYPFCTIEPNVGIVAVPD
                     ERLDKLAEMYNPEKITPTVIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHVVRCF
                     EDGNIVHVDGSIGPKRDVETINLELIFADLEMLERRIDRTRKNLKSGDKKFQIEMELYE
                     SIKAHLESGKPARSMTFDSEQQQIVDQLFLITLKPVLYAGNVSENDLSSLEANKFLAEL
                     KEIAADEGSEVMVICAKVEEEIAQLADEEKADFLEAMGLDESGLDKLIKASYKILGLIS
                     YLTAGPQEVRAWTIIKGTKAPQAAGKIHSDFERGFIRAEIVAYNDLMACGTYNAAKEKG
                     LVRSEGKEYVMQDGDVTLFRFNV"
     PFAM_domain     12563..12877
                     /aSDomain="MMR_HSR1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01926.25"
                     /description="50S ribosome-binding GTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_76_0010"
                     /evalue="4.10E-24"
                     /label="ctg22_76"
                     /locus_tag="ctg22_76"
                     /protein_end="107"
                     /protein_start="2"
                     /score="85.0"
                     /tool="antismash"
                     /translation="LGIVGLPNVGKSTLFNAITKAGAESANYPFCTIEPNVGIVAVPDE
                     RLDKLAEMYNPEKITPTVIEFVDIAGLVKGASKGEGLGNKFLSHIREVDAIVHVVRCFE
                     D"
     PFAM_domain     13394..13645
                     /aSDomain="YchF-GTPase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06071.15"
                     /description="Protein of unknown function (DUF933)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_76_0011"
                     /evalue="1.40E-37"
                     /label="ctg22_76"
                     /locus_tag="ctg22_76"
                     /protein_end="363"
                     /protein_start="279"
                     /score="127.8"
                     /tool="antismash"
                     /translation="LISYLTAGPQEVRAWTIIKGTKAPQAAGKIHSDFERGFIRAEIVA
                     YNDLMACGTYNAAKEKGLVRSEGKEYVMQDGDVTLFRFN"
     CDS             complement(13797..13904)
                     /locus_tag="ctg22_77"
                     /transl_table=11
                     /translation="MLERKVLETGDRVSCTYDEAGDRKTMSDAWRNKFL"
     CDS             complement(14174..14638)
                     /gene_functions="regulatory (smcogs) SMCOG1201:response
                     regulator (Score: 65.4; E-value: 8.3e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg22_78"
                     /transl_table=11
                     /translation="MADIQVVIFTLNNELCSIEASMVFKIEKYSEVSLIPQMPDYIKGL
                     YDLRGRVVPVVDLNKKFNLGDSEITKKTKIIITEKEGQLFGFMVNNVLEIINLNENSID
                     KSEAIIKVNNKKYIKGVGKKDEKLFSIIDLNEVLLDNEVEQVTEVIASKV"
     PFAM_domain     complement(14225..14626)
                     /aSDomain="CheW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01584.21"
                     /description="CheW-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_78_0012"
                     /evalue="2.80E-32"
                     /label="ctg22_78"
                     /locus_tag="ctg22_78"
                     /protein_end="138"
                     /protein_start="4"
                     /score="111.3"
                     /tool="antismash"
                     /translation="QVVIFTLNNELCSIEASMVFKIEKYSEVSLIPQMPDYIKGLYDLR
                     GRVVPVVDLNKKFNLGDSEITKKTKIIITEKEGQLFGFMVNNVLEIINLNENSIDKSEA
                     IIKVNNKKYIKGVGKKDEKLFSIIDLNEVL"
     CDS             14843..15046
                     /locus_tag="ctg22_79"
                     /transl_table=11
                     /translation="MEKSRIERLNELAKKAKTSSLSEAELAERDELRKEYIAAFKANLK
                     ATLDNTVIVDKDGNRRSLRKDN"
     PFAM_domain     14855..15019
                     /aSDomain="DUF896"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05979.14"
                     /description="Bacterial protein of unknown function
                     (DUF896)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_79_0013"
                     /evalue="5.90E-22"
                     /label="ctg22_79"
                     /locus_tag="ctg22_79"
                     /protein_end="59"
                     /protein_start="4"
                     /score="77.4"
                     /tool="antismash"
                     /translation="RIERLNELAKKAKTSSLSEAELAERDELRKEYIAAFKANLKATLD
                     NTVIVDKDGN"
     CDS             15210..15995
                     /locus_tag="ctg22_80"
                     /transl_table=11
                     /translation="MDRFKKEIVDILDDIIKPRGIYERNDVPVRQLEGLEIQKGFLKGP
                     FDTLVEMTENGVKFLVDVENGQKTGFFLDQKENRAAIAPFVKGVKVLDCFTYTGSFALH
                     AGLFGADSVLGIDISEHAVKCAAKNAEINGLDTVVKFQAANTFDILREFYDKGETFDTI
                     VLDPPAFTKTKNAVQGAIRGYKEINLRAMKIIKRGGYLITCSCSQHVDSELFMDILYDA
                     ADSRRKVRVAEYRSQAKDHPVLLASPETGYLKCAILQVV"
     PFAM_domain     15330..15881
                     /aSDomain="Methyltrans_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10672.11"
                     /description="S-adenosylmethionine-dependent
                     methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_80_0014"
                     /evalue="1.70E-21"
                     /label="ctg22_80"
                     /locus_tag="ctg22_80"
                     /protein_end="224"
                     /protein_start="40"
                     /score="76.8"
                     /tool="antismash"
                     /translation="FLKGPFDTLVEMTENGVKFLVDVENGQKTGFFLDQKENRAAIAPF
                     VKGVKVLDCFTYTGSFALHAGLFGADSVLGIDISEHAVKCAAKNAEINGLDTVVKFQAA
                     NTFDILREFYDKGETFDTIVLDPPAFTKTKNAVQGAIRGYKEINLRAMKIIKRGGYLIT
                     CSCSQHVDSELFMDILYDAAD"
     CDS             16162..16650
                     /locus_tag="ctg22_81"
                     /transl_table=11
                     /translation="MLLLFITLLVLIKLTELTYRVFYKRKINQILKVINTKEDLLYLNF
                     KDYMSVIMEVLKRLGYRVKPTAACGIDGSGLLLNNIQFTEVWKHGLQQVIDVELAMNLF
                     KCMSDNSIYRGMLITLGDFKSCTKVYCHKNVIECINGDQLLDMCKSVQNAKIVLEPAK"
     CDS             16819..17505
                     /NRPS_PKS="Domain: ACPS (104-166). E-value: 4.1e-15. Score:
                     47.6. Matches aSDomain: nrpspksdomains_ctg22_82_ACPS.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 172.8;
                     E-value: 1.1e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_82"
                     /transl_table=11
                     /translation="MVDTYRIRTNSFLDSKATDSLMQLVTNEKKERIKRFVHREDALRC
                     LLGDLLSRYALGKRTGLKNSELKFMVNEYNKPLLVAPEHLHFNVSHSGNWAVCAVADKL
                     VGIDVEYVKNIDLKIAERFFTNYEYDSLVKQDPKNRIRYFYTLWTLKESYIKADGRGLS
                     LPLDSFSIEINNDSISVITDNELKSCFFEMYEIDNFHISSVCSLDSSFNTTLKEVTYFD
                     LLQTLA"
     aSDomain        17125..17457
                     /aSDomain="TIGR00556"
                     /aSTool="tigrfam"
                     /description="pantethn_trn: phosphopantetheine--protein
                     transferase domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg22_82_0004"
                     /evalue="1.50E-17"
                     /identifier="TIGR00556"
                     /label="ctg22_82"
                     /locus_tag="ctg22_82"
                     /protein_end="213"
                     /protein_start="102"
                     /score="61.8"
                     /tool="antismash"
                     /translation="KLVGIDVEYVKNIDLKIAERFFTNYEYDSLVKQDPKNRIRYFYTL
                     WTLKESYIKADGRGLSLPLDSFSIEINNDSISVITDNELKSCFFEMYEIDNFHISSVCS
                     LDSSFNT"
     aSDomain        17131..17316
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg22_82_ACPS.1"
                     /evalue="4.10E-15"
                     /label="ctg22_82_ACPS.1"
                     /locus_tag="ctg22_82"
                     /protein_end="166"
                     /protein_start="104"
                     /score="47.6"
                     /tool="antismash"
                     /translation="VGIDVEYVKNIDLKIAERFFTNYEYDSLVKQDPKNRIRYFYTLWT
                     LKESYIKADGRGLSLPL"
     PFAM_domain     17131..17370
                     /aSDomain="ACPS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01648.22"
                     /description="4'-phosphopantetheinyl transferase
                     superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_82_0015"
                     /evalue="1.30E-16"
                     /label="ctg22_82"
                     /locus_tag="ctg22_82"
                     /protein_end="184"
                     /protein_start="104"
                     /score="60.9"
                     /tool="antismash"
                     /translation="VGIDVEYVKNIDLKIAERFFTNYEYDSLVKQDPKNRIRYFYTLWT
                     LKESYIKADGRGLSLPLDSFSIEINNDSISVITDN"
     CDS             complement(17723..19297)
                     /locus_tag="ctg22_83"
                     /transl_table=11
                     /translation="MCKLSNMIRVSIIILAVALVVSSGQVSVFAAEVQHPDGWTKETHG
                     DVDGNYTVVFPDNKVQRMDITISPENYRTMETDLNNLNMTSTQNPVYVPATIKFNNITW
                     WNVGIRYKGQSTLFTPKMSGKHKFPFRLNFDKFEDQYPEIKNQKFYGFKELAFSNNWFD
                     PSFVRDKVFSDMLRDGGIPAARSTFCRVYIDTGSGPVYWGLYTMTEDPADEMLKTQFPN
                     SKGNLYKGETGAGADLTTFNQQGFEKKTNEKANDWSDLQALVNKLNAPRTNAASWRAGL
                     ESVFDVNKFLRWLAINTAAVNVDTYGWVTKNYYLYQDLSNSGRMIYLPCDFNMSLNNNP
                     FGMPMPGIPASLSLREIGNNWPLIRFLMDDPVYNNIYHNEMQNAMSGCFNQTAITSRIR
                     QLHELVRPYVVGAERESSNYSFLSYGETQFNQAVNDLVNHVSSRHTTVRDYLATVPITP
                     IFKKGDINNDGQVDALDYALLKKHLLNEAILSGDALKAADVDSSGSVDTLDMVMFKKYL
                     MGQIPGF"
     PFAM_domain     complement(17747..17914)
                     /aSDomain="Dockerin_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00404.20"
                     /description="Dockerin type I domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_83_0017"
                     /evalue="2.60E-14"
                     /label="ctg22_83"
                     /locus_tag="ctg22_83"
                     /protein_end="517"
                     /protein_start="461"
                     /score="53.3"
                     /tool="antismash"
                     /translation="KGDINNDGQVDALDYALLKKHLLNEAILSGDALKAADVDSSGSVD
                     TLDMVMFKKYL"
     PFAM_domain     complement(17960..18973)
                     /aSDomain="CotH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08757.13"
                     /description="CotH kinase protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg22_83_0016"
                     /evalue="1.20E-67"
                     /label="ctg22_83"
                     /locus_tag="ctg22_83"
                     /protein_end="446"
                     /protein_start="108"
                     /score="228.9"
                     /tool="antismash"
                     /translation="IRYKGQSTLFTPKMSGKHKFPFRLNFDKFEDQYPEIKNQKFYGFK
                     ELAFSNNWFDPSFVRDKVFSDMLRDGGIPAARSTFCRVYIDTGSGPVYWGLYTMTEDPA
                     DEMLKTQFPNSKGNLYKGETGAGADLTTFNQQGFEKKTNEKANDWSDLQALVNKLNAPR
                     TNAASWRAGLESVFDVNKFLRWLAINTAAVNVDTYGWVTKNYYLYQDLSNSGRMIYLPC
                     DFNMSLNNNPFGMPMPGIPASLSLREIGNNWPLIRFLMDDPVYNNIYHNEMQNAMSGCF
                     NQTAITSRIRQLHELVRPYVVGAERESSNYSFLSYGETQFNQAVNDLVNHVSSRHTT"
ORIGIN
        1 atatttacta ctttgcctga ctgctgctgc tttttggaat tgttgaagaa gtgcgtttga
       61 ataggttcgc ttttaatatc gtccctatag tcggtatcgc gaagatctaa gtcttcatcc
      121 tcttcctcgt caattgcttc ccatccgacg aaattaaaaa ctttgtttag aagttttgac
      181 atttcaaata cctcctgcgt ctttagtaat ttatttaatc ttttcgcttg taaaatttac
      241 ttctttgtat aatccctctt tccaaatata ccggtaccga tcctgacaat gtttgccccc
      301 tcttcaatgg ctatctcaaa atcgttgctc atacccatgg aaagataatc catattaaca
      361 ttatctatat ttttatgctt tatgtcaata tatatattat aaagattcct aaatacaggc
      421 cttatgacct gtgggtcctg agtaaatggg gctatggtca taagtcctct gagagaaata
      481 ttttccatcc gggaaattat acctacgtat tcatctacat caccaggact tattccaaat
      541 tttgtatcct ctcccgaaac attgacctgc aaaagaatat cgatcttcct cccatgcttt
      601 gcagcccttg agttaatctc tttggcaagc tccatgctgt ccacggaatg tatcatttca
      661 accttatcga ttatatattt gactttattg gtctggagat gcccaatcaa atgccattta
      721 cagtctgaag gaagcctgtc atatttttcg gtcaattcct gcactctgtt ctcacccata
      781 tcaagaatac cgtattcata tacatttttg atcctgtctg cctcaacagt tttggtaacg
      841 gctatcaccc tgatgtcttc cactgagcgg ccgctctttt cggctgccgc tcccaccctt
      901 ttaaaaatat tatccagatt gcttttaatc tctgtatcaa tcaactgtct gtccctcctg
      961 tatattctta ggatttagga tatatgtatt atacaaggcg atggtatttg tattttcgcc
     1021 ctctaaattg tcgataatga ctgcactctc attcatacct acgatcctca ccttttttat
     1081 ggcagccgta tgacccttga caacggtgat cagcgcagtt ttgtttttgg tatcaatgtt
     1141 ctgcaaagaa ctgtagggta ctttcaaacc cgtatagctg gataatatta tatctgcgtt
     1201 tacccttctc aaacccactg tctcatttaa gcccgcatca aatttaaagg ctatgattct
     1261 ttttccgtct ataaggtcag agctgtaaac tatctttgct tcgatattca aacccgtatc
     1321 attgatcctg agggtgacgg ttttatcaag ctgcagggat ttgcagtatt tttcatcaac
     1381 agccgtcacc atgtagctgt ccagatcctt gaccagcttt gcaacaggtt tccccttggc
     1441 cgcatcaatg acattgaaat ccctgttggt ttccctggtt gttattttct caagctcctt
     1501 cggtgtaata ttcctgatgg tctccggagt gagtatggat tcatagccgt ctatggcata
     1561 ggatatcaat cctgaactct ttgtccgtat ttctttgata ttgttgttca atttgccctg
     1621 tatagcggct ttttcattct taagcttgtt tatatacgcc gccgacttgc tgctgtcacc
     1681 aaaaatatca gacttcctgt aaacgatcct gtctatgctg gaaagactgt tgtagctttc
     1741 aacaaggctg ccgcggatgg attgctgggc aagattttta acctcttcaa ttatttccga
     1801 atccagtttt tttatgtcac tggaaaacat atttatattt tccttctgtg ccttttgtgc
     1861 ccgctcaatc tccatttcct tggtttttag ctcctcatag gtggataccg gaacattttt
     1921 gactacagaa gctattctgt aaaaggcagg gaccttctcc ccgtctaccg catccattac
     1981 acaattgcct gtttcgggcg acaaaatgag ttcttcattt cttatgaaaa ctccgtctat
     2041 attctgtgtg tcctctatct tgcctatttt gagtatgtca gtttcgacac cgtttccata
     2101 tatgataaat aacagcgccg gaaggtatat taacagaaat acacctgcta tgagggttcc
     2161 tattctgaca ctctgctttt taaaaacact catgtacaac tccatttccg cagcggctat
     2221 ttgtccctgc tattgaacaa tttctgcagc gctatgatat ttccaagctt tacatgctca
     2281 tataccagac cgccctgcat atacgctata tacggactct ttatgggcgc atcggcgctg
     2341 agctctatgg aggagccctg aacaaaggct cctgccgcca ttatcaccgg ggaatcatag
     2401 ccgggcatct cccagggctg gggtgttaca taggaatcca ccggtgaacc cttctggata
     2461 ccctggcaga atgctatgag gctttgttcg ttatcgaatt ttacagcttg gattatgtca
     2521 cttctttttg catcgactga aggcagtgtt tcaaagccgg cacgttccat aagggcagca
     2581 cagaacaccg ctcccttcaa gctttcggct acaacatgag gtgccatgaa caggccctgg
     2641 aacatcagtc tgttattgcc cagtgaagcc cctacttctt ttcccagtcc cggagatgtc
     2701 agtctaaagg cagcctgctc caccagctct tttctgcctg caatatagcc ccctgtcaaa
     2761 gccagtccgc ctcccggatt ttttataagg gagcctgcta ttatatctgc ccccgcctca
     2821 atcggttcaa cctcttctac aaattccccg tagcagttgt caaccatgac aattattgaa
     2881 ctgtttatgg acttgacagt gcttataaca ctttttatgt cttcaatgca caatgcatct
     2941 ctccaggaat accctcttga gcgctggagc attgccattt ttgttgaagg cgtgacaacc
     3001 ctgcgtattt gttccaaatc aggtttcccg tcaggcctta attccacctg tctgtaattg
     3061 actccgaatt ccttcagaga accgcagttc tcacctctga tccctattac ttcctccaat
     3121 gtatcatagg gcttgccggt aacggccacc agctggtctc ccggtctgag attgccaaaa
     3181 agacacagtg ccagagcctg tgtacctgag actatctgat gtctgaccag tgcatcttcc
     3241 gcacaaaaaa tatttgcata cacactgtcg agaacttccc ttcccctgtc atcataaccg
     3301 tagccggtag ttccgttgaa atgtgaatcg ctgagtttgt tgtcctgcat tgccttgatt
     3361 acttttaact ggtttatctg tttggtattc tctattcttt caaaaacctt ctgagcgtcc
     3421 ttttcggcct gctcagccag ttcaatcacc ctgtcctcaa tttcaaagta ctgtttcaaa
     3481 tattccctta ttttaaaatc catcaaccat tcctctttcg tataagtata aataaaaatt
     3541 agctttttaa tagaattata taccattttg aagccgctag ctagtgtctg taacatctaa
     3601 aacgtatatt gccggcgtag aaaatttttg cagctaaggc ggaggataaa tgcaataatt
     3661 aagagataat aaatatttaa ttgtaattga acaaaatttt attcaaattg gaagtcgact
     3721 tatgtgctat tcaaattctg caatttttat gctttttaaa atacctaaaa tctgcccctt
     3781 gtttttttga aatgaagttt cactcatttt tattattgca ccgttgaatg catctccaag
     3841 aacaagataa atctttatat tttcttgtga tttctggtat agaattttcc ctttgactcc
     3901 ggcagttgtg gtaaagtttt cacttgtaaa accgtctgtc aggaggccga tgtgaccaaa
     3961 ctgatgataa acatagatga gatcattttt attgctttca acatatatgg aaataccacg
     4021 ctggggatca ccatccggca aatcaggtga tgatttgcca tcaatggaaa cttcccactc
     4081 tgcaggataa tctacactta atttaaattc atcattactg tatgctttgg gattttctat
     4141 tgtatatttg cttatatctg caaataactt tgattcggtt ttttccagtg taacttcatc
     4201 tccggtggaa gttgaagtta tttgattccc atgtgtgcca taaggttcat tcgagttatt
     4261 ttcatttatt gtactgcacc ccggcagcag aattaaaatt gacagaacca atacaaccag
     4321 tttaaagctt gccaaccact tcataaaata gtacctccac ttattttctt aattccatta
     4381 tatacaataa aaattaaaat gccttcgtaa agagcaataa aaaacttttt atgtttacga
     4441 aggcatttat aattacctat tttttagcga aaggcatata tttcctattt gccaattgat
     4501 cataagtcca atatgtaata tcacaataag gatccgtttg ctcaaaacac tgaacttttg
     4561 aatccgtggt aaaattgact gcgatcacaa aaacatggcc tccagtgttg tctgaagttc
     4621 gatatacaac agcatcaccg gtctgcaaca acttatatga attttttagt tctgaagccg
     4681 agggcgaagt aggagtatct gcattataac tgccgacttt tggataagta ccttttttta
     4741 tgccattata aaaacttaaa gtggtttgtc ttgatatccc ccatgagaaa cttgtaaaac
     4801 cggaacaatc attcccatat cttggcataa tatttggaga agtaattgaa gtataaaaat
     4861 cactttttga ctgtgcagat ttaaagcctg cttcatctac ttggtttggt gtttgtgaat
     4921 atggaatacc aatacaggtc gtatctttct caaatgtata taagtctttc catcctgtta
     4981 aatctttagc aggtctccat atatacgcta tcatagccat agccttatca cgaatttctt
     5041 gtctttcaga attggttaag ctaagagttc caagcatgtc atcattgctt ttcctacttt
     5101 taaaaatttc atttaaagcc ttttcttctt taataaggtc tatctctttt aaaatttcaa
     5161 catcaatata tttttcaaac ccttcgtatg atactttgat ccttgttttc cctttacctt
     5221 ttgctaatat cctgccctca aatgcaacag caatattttg attatcagtc tcccattttg
     5281 catcatagtt aacattcatt actgtattgt catccaatgt tgcataacaa tcaacaaatt
     5341 cagaatatcc gttactttca ataaccacat tacttgctga agtttccaaa cctacacata
     5401 ctttttctgt tccaatgaat aaatccggtt taacagcagg atcatcattt tcagcataaa
     5461 taccaaaaac cgatatgctg aaacacaaaa caattaaaat acataaaaaa cttttaaatc
     5521 ttttcataaa aatacctcca aaatttatag tttcatggga taagataaca agtacctgac
     5581 tttcctcctt cttattagtt ctctcttcac aaatatccca tagaggtata taatgaatat
     5641 accttttctc tgtaaagagg ttggtgaaag ctttcgatca agaataccga ccaagtaaga
     5701 attgatcgaa agcttccttt aaactacaga taatattaca gaatacatta tcttccagtt
     5761 tatgtttatt gtaacaccgc ttggaatata tttcaattaa ttacaatatt atttattttg
     5821 tgattttttt cgttttatca tttcgagcct gccaatatgt ttatcatatt tttccgtaat
     5881 ttactttaca aaataagaat attcaaagtt gagctaatta tttaatgcct gtataatagc
     5941 tgtagaagtt ttattatggc tgctcaacca tggaggaaat aatgatttta gagcacaaag
     6001 ctgatatttc cgatgcaggc aggcccctga aatacattct gaagggcaga ctgcaaatat
     6061 ccgaaaggtt ggttaaaaaa ctaaaattcc aaaataaaat ttatgtaaac agtgaagctg
     6121 ttcacgtaaa ttttattata aaagaaaacg atcagattag agttgaactc gaacttgaag
     6181 aatactgtga gtatattgaa ccacaggaca ttcccataga tataatttac gaggataact
     6241 gtctcctggt gctgaacaag cagtccggaa ccgtggttca ccctaccagc agccatcccg
     6301 attccacaat agcaaacggg attgtttatt atcttaaggg aaaaggcatt tccaaaaaag
     6361 tcagacctgt cagcaggctg gacagagaaa cctccggcat tattatcttt gcaaaaaatc
     6421 agtttgcaca ggaggcactt atccggcaga tgaaggcaaa aatttttgaa aaggagtacc
     6481 tgggcattgt ccagggtata ccactttcaa acgcaggcac cattgatctg cccattgaca
     6541 gaaagcccgg aagcattatg ctgagacatg tttccgagac gggagcacct tcggtaacac
     6601 attatgcggt catggagagt ttccctttgc ataatgcagc tttacttaaa tttaagttgg
     6661 aaaccggaag aacccaccag atcagagtcc actgccaggc catgggtttt cccatatatg
     6721 gagatacact ttattctgaa aatacaggtt tattaatttc ccgccaggct ctccattccc
     6781 atattaccaa aatagttcat cctgaaaccc ataaggaagt tatcttcaat gctgaactgc
     6841 cccaggacat gaaggcagtg ctggaaataa tgcgaaatag tctgtaaata ttttacatca
     6901 acctcctgat atgctactat cttcatatga aatagatttg cgccgggtta aaataccggt
     6961 tctacaaatg aaaaaggatt tgtcaggagg aattttatat ggatatttta aaggatcggt
     7021 attctataac agagttaagc gaatgtttaa atataactga tcatgcttta agattttatg
     7081 aaaaggagtt cgggctgaaa atccccaagg acagcagagg caggagattt tataccaccg
     7141 agctggcgaa tgtcatgtac cagatcaagg atatgcgcga tcagggactc gaacttaaag
     7201 ccataagaaa aatactggaa gatgagcata tcataaaggt caatcctccg ggtacagctt
     7261 taaattcatc agttcagctt aatgaggctc agttgcccgc gatcatgggc catgctgctt
     7321 cacaactgag cagcaccgag cttactgcaa ttatcgatgc actcaacaat atgaaggaac
     7381 aggtttttaa taatatttct acagagcttt tgtcaaccag ggaacagata tcaaaggaga
     7441 tacataaatc gaagcttgag ctgggagcat gtgttgaaaa cagttcaaga aaacttgaga
     7501 tcaaacttga cagacacttc caggaggtcg acagaaatat caccagctgg agagaacgga
     7561 aaagcacctc tcttggggga aggctgaaga aattaatcgg aaaggcgtaa atggaccaga
     7621 cttatcttca aaaatattga tattttcatg aatatactca ttgctaaatt ttgagactaa
     7681 cataacttta tactcctttt tgtcatccgg taaaaaggcg ctgccttttt tataaagaca
     7741 acgccttttt gttttacacc tgattagata tgatcacgac accaactgct tggcgctgag
     7801 caatcgttat ttcacagact tactctcatg ttttctgtat taaatttgca gcacttattc
     7861 agtacaatgt gcagcataga aaatatttta tttcagctta aagtgtattt tggatttttc
     7921 agcatccttc tctcctgatt tacgaagcac taaataattg gtatcattct tatataccgg
     7981 aataattgct tttccttcgg cagagtatga ttccgtcata ccaacatcca atctcgcagt
     8041 cccggccttg cttaccgcac tgctcagaga gccttcaaaa ccatagtctc ttgttccgat
     8101 aatccaactt ttatccgctg tttccactcc ccagatatta ggggtccaat atgttgacaa
     8161 actgcttttc atgcctgtat tatttatcaa tacttttgca tcttttactt cccatagtat
     8221 gttaaccata acatattcaa tccgtgaatc atttgaacta ttcttaattc ccaatgcagc
     8281 aatctcatcc ttggtaattg gagtaacttt ttttacggta caagaataag tgccgctgat
     8341 tttattatct ttctctgtca actgagaggt tgatgaccag gtaaactttt catttatagg
     8401 aacgggcgag cttaaagaac catcggcgct tgttgttgaa ccgcttgttt tggatccgct
     8461 tgaagaattg ccatcctgcg tcggtatgcc atcttcaccc gctgtacttg taacattata
     8521 tgtaccgtca cctttactgt catatttgac cgcagcacca aggtcttctg caaattcctt
     8581 tattggcaca tatgttttcc cattatagac aatgggatat aatatctcct ttttgtcatt
     8641 cttcggctgg aattttgcat tatcgatatt gataacaatc cctttattaa ggaacgcctt
     8701 gatggcggta acattcgttg ccgcaaatgc gccagaagta aaggaaagaa gcaccagaac
     8761 agctacaatc gataaatatt ttttcttcat ttttcgtcct ccgtttgtca tttattattt
     8821 gtaaatacgt tttaatcaca caccaatgga atatgactgt attgacttag aaaaaaccat
     8881 tttatccatt taattctaac atcattgtcg aattatgtaa atattttttg taaaataatc
     8941 cttcttttac atattcgaca caagcgtgat ccactgcatg aagcattgta gaaatctgtc
     9001 ggatctattc aactgtttgc tccattttga tacggcaccg tattgtgccc ggttagtaca
     9061 ctaaaagtat aaaaaacgct attgttataa ctaaaattaa aatcaggata ctaagttatt
     9121 tttatatctc aaataacatc aaactttgac tccatagtgt agaaattatt tctataaaaa
     9181 atataaataa ggcacaaaaa cagggctgcg cagctatttt tagctaatgc gacaacccct
     9241 tctcaattta tttatattca actttatccg tttatcagtc ttttaaagga aaaccctttg
     9301 catccttgtt tatggtacct gccaatatca gtataccttc gatcaaaccc catatatata
     9361 taaacggtga gaatatgaag catgatagta acgttaggag cagctgtgcc aagccaagtc
     9421 cgatatatcc caaatagaat ctgtgaactc cgaacattcc gaggaaaatt ccgaacaaac
     9481 ctgctgcaag tttggatttc tgctggccat atgcgttaaa attaaccccg catttcatac
     9541 agacctgagc cattgaatct gttatatcac cgcacaacgg acaataatta tttccctttc
     9601 caacaggtac tccgcacgca acacatatcg ctgcctgatc gttcataacg ttaccacaat
     9661 ttctacaata cataatattt acctcctgtt ttgatattta tcgttaagtc attcgtcttt
     9721 tcatacaact ttcgaaaatg tattacacct aagtatacgc ttaagtacaa agtatgtctg
     9781 aaataaatta tcctatatta aaattagtag aattttacat atagttcctt ttatttatac
     9841 ctgattaata tatattaatt ttttaaaaaa gtctactaaa aatgatgtat ttaggcagtt
     9901 tacaggtgtt catcgccaaa acttcaaaaa tatggtgatt tttgtatggc gctatgataa
     9961 aattggaata tattgaatat ttatgtaagg agcagattaa atgaggtttg tccaaaagtg
    10021 gtcatatgct tgtgcaaaac atttagcgta tgttttgaat gaaaatcata ataagagatc
    10081 agtttactat tatggctttt atgttttatt tggtacactg gtaaaaggta ttatattgat
    10141 ttctgtatct ctacttctag gaatttttat tccagccttg gtgactgtag tagtattggc
    10201 ctccttaaga ctatttgcag gagggtatca cttcgataca tacggtaaat gtctttttgt
    10261 ttcaatggca ctcaccataa tgactgcttt gatatctcaa tatactcata tctactggag
    10321 tatggcagca gttgctatat ttttgtttat tgtatctgca tttagccttc atatgctgat
    10381 aaagtatgct ccaaaagata caccaaccaa acctataacc gatcctgccg ctattattaa
    10441 atttaagagg ctttccatcg tataccttgg catattgctg gtactttgct gcattctgtt
    10501 attttttaac ctgaaaatgt atgttatagc aatatgtttc ggagtgctgc ttgagatatt
    10561 ttcaataacc cccgcagggc atggcttttt taatttcatt aaatccggat taaataacgt
    10621 ataactttat ctttttaatt ataaatttaa atcagattcg actatgtcag ggttttcctg
    10681 ccgactaccg taggtgcttt gttatccaat attttaataa atattggttc gcattcaggc
    10741 ttttttcagt ttttaacccc gcttttaatg tatgttctta taatatttag aaatgatatt
    10801 ttcggagatg taagtgcaat aaagtggata ttaaaagctt ttatcttcta tataatggct
    10861 ttctttctat tggaattact gaattcatat atttgccgtt tgtgttatat ggaaccgggt
    10921 tgacgatgga tgatatcaga aacaatttat taatatactt tatgacctca ctgcctgcac
    10981 gttttttaca gcttagttta attacatatc tgataagccg gaaacgtacc ctggtgaagg
    11041 gatggttaat aaaagccata ctttcaagtc ctgtagttgc agtgatactt tgcttattag
    11101 tacttgctaa tatactgtct cttcaaatgt tcggctcagc tattatattg gacaaattgc
    11161 ttatatctat acctcgtact tcacaaatat tcataattac aggtgtcgct ttatttccaa
    11221 tacttaatat ctcaggaatt ccatggtaac caaagataaa aagcttgctt cggaaaaact
    11281 aaataaatta ttgaaagata tagagttgta tgcggatcat tcaaattttg acaatgttag
    11341 gtggaaacta aatgatattg gcatgggcat tgaggatgtt gcgaaaaatc tttataaaga
    11401 acatggaaca caataagcaa ataatttttt attggcaaaa gaggtgatag taatgaaaat
    11461 atttccgttt tatttaccgt ttcatttctt tataatcatt gctgcctacc gtagcaaccg
    11521 gtccttgatg tccattgtca actttaatat ggctcatttt tcaggactat aaaatttcct
    11581 tgaataaata ctaacctgta gaaaaaactt tatatgtttt ggtaattatg atatttgtat
    11641 ccgttttatt tattgtatta tttatcgttt gatttcttta taatgagtac tgcccactgc
    11701 cgcagtccgt tccttgatat ccattgccaa ccccaggtac ggttcatttg agggatcatg
    11761 tatgaagtcc cttatctctt cgggcaaatg cttaagatac ggttctctta tgtcactgta
    11821 acctatcagg taatccacag atacgttgaa atattccgca agctgcttca gctttgatat
    11881 tgacggttcc cttttgttac ttacataacc gttgaaggtg ggtattttta aattaagctg
    11941 gatggcaact tcctgctgac caattgtttt aacctttcac caatcgttat ctccataggt
    12001 tcattttcct cacatttatt ctgacatatt tcttataata ttataactat aaatttgttt
    12061 atatgtcaat taattacttt tttctcaaac ttcataatga cttttttcaa ctattttttt
    12121 aaaattttta tttgacaaat tgcgttttgc attttataat aaatttaata ccaatttatt
    12181 acataattca actatattgg aagtttgcat tacgaaccat cgcacgaaca cattagacaa
    12241 aaaatgagct ttttgacgtt ttatgagaaa aaatgttgga tagggggttt taatatgctg
    12301 gttgatgaaa taaataactt aagagaggtt cttaatgaac aggttgaaaa ctgcagtctg
    12361 gacaacgagt cgcttttggc tttaagtcag gatctggata aattgattgt tgagtactat
    12421 aaagatgtac ttatggtatg aaatatccga ttgatatgtc ccttgaattt caactattat
    12481 tgcattgaag tactatatag tatataattt ttatggtatt ttcgatgaca gtaataatga
    12541 gaggatagat atattaatga aactaggtat tgtaggactt ccgaatgtag gtaaaagcac
    12601 actgtttaat gccataacaa aagccggtgc agaaagtgca aactaccctt tttgtactat
    12661 tgagcccaat gtaggcattg tagcagttcc tgatgaaaga cttgacaagc tggccgaaat
    12721 gtataatccc gaaaagataa cccctacggt tattgaattt gttgatattg ccggtctggt
    12781 taaaggtgcc agcaaaggtg aaggtcttgg aaataagttt ctttcccata ttagagaagt
    12841 agatgcaatt gttcacgttg taagatgttt tgaagacgga aatattgtcc atgtagacgg
    12901 ttccatcgga cctaagagag acgtggaaac cattaatctt gagctgattt ttgcagatct
    12961 ggaaatgctg gagagaagaa tcgacagaac caggaagaat ctcaaatccg gtgataaaaa
    13021 gttccagata gaaatggaac tgtatgagtc aatcaaagct cacctggaaa gcggaaaacc
    13081 tgccaggtca atgacctttg acagtgagca gcagcaaata gtcgaccagc tgttccttat
    13141 cacgctgaaa cctgttttgt acgcggggaa tgtatcggaa aacgacctct cttccctgga
    13201 agccaacaag tttttagctg agctgaagga aattgccgcc gatgaaggct cagaggtaat
    13261 ggtcatctgt gccaaggttg aggaagaaat cgctcagctg gctgatgaag aaaaggccga
    13321 tttcctcgaa gcaatgggac ttgacgaatc cggactggac aaactgataa aagccagcta
    13381 caaaattctc ggccttatca gctaccttac cgcaggcccg caggaagtca gagcctggac
    13441 cataattaaa ggcacaaagg ctccccaggc agcaggcaaa atacacagcg attttgaaag
    13501 aggctttatc agagctgaga ttgtggcata taacgatctt atggcctgcg gcacctataa
    13561 cgccgcaaag gaaaagggcc tggtcagatc agaaggcaag gaatatgtta tgcaggacgg
    13621 cgatgtgacg ctgttcaggt ttaatgtgta agaacttaaa agtgatacat ttgatgatga
    13681 taatataacg ttttaacccc cttcatatct ttaaatggag atatgaaggg ggttttgttt
    13741 aaaatgggtt taaactaaga cctggtcata gctataactt attcttgccg taatgtctat
    13801 aaaaacttat tccgccaggc atcagacatg gtttttctgt ctccggcttc atcataggta
    13861 cagcttactc tatcacctgt ctccaatacc ttcctttcca gcattagtct cctgttgtca
    13921 taagtataaa cagtattgtt gctgttttag tcggtactgc aagccgcatt tcccataagg
    13981 tcacactttt ggcttaatct ttattatcag gattcaccac tgttttcagg ctgtcgaaaa
    14041 ccgtatatct atacgtgtca gcttgcctct tccctctgtc atagtatgct tgccgccttg
    14101 cttgtcatag cattatacca aaaaaacagc ctatatgaat ttatcatata agctgcaatt
    14161 ttaaccgtta ctactacacc ttgcttgcaa ttacttctgt aacctgctca acttcgttgt
    14221 caaggagaac ttcgttaaga tcaatgattg agaacaactt ttcatccttt ttcccaacgc
    14281 ccttaatata tttcttattg ttgactttga ttattgcctc tgacttgtca attgaatttt
    14341 cattcagatt aattatctca agaacattgt ttaccataaa gccaaacagc tgtccttctt
    14401 tttcggtaat tataatcttt gtctttttag taatttccga atcgcccaaa ttaaactttt
    14461 tatttaaatc aactacggga actactctgc ctctgagatc ataaagtcct tttatgtaat
    14521 cgggcatttg tggaataagt gatacttcgc tgtatttttc tattttgaat accattgatg
    14581 cctctatact gcataattca ttgttcaatg taaatataac aacttgtatg tcagccattc
    14641 ccgacacctc ccaaattttg tgtatcatat ttttaataat atcacacaat acacgctttt
    14701 taaaggacat tatttttgat ataataaatt ctgtgccatt ttgaataata aatacaatag
    14761 taataattca tatcctccat attaaatgta aaaaatgctg caaataaaaa aggttttaaa
    14821 taatatagat aggacggtct ttatggaaaa aagcaggatt gaaagattga atgagcttgc
    14881 taaaaaagcc aaaacttcat ccctttcaga agctgaactt gctgaaagag atgaacttag
    14941 aaaagaatat attgccgcct tcaaggcaaa tctgaaggca acgcttgaca atacggtaat
    15001 cgttgacaaa gacggtaaca gaaggagtct gagaaaagac aactagacat gtcaaaagcc
    15061 tcattcagaa aattaaatat gcccggattg agaaaacaac ggcagatgtt aactgctgcc
    15121 gcgcggtttt ttccgaatcg gactttctgc cggcactggt cgttgacaaa ttctcggata
    15181 ttctggttgt tcagactctt gcacttggta tggacagatt taaaaaggaa atcgtcgata
    15241 tcctggacga tataataaaa ccccgcggca tatatgagag aaacgacgtt ccggtcagac
    15301 agctggaagg tctcgaaata cagaaaggtt ttcttaaagg cccttttgat acacttgtgg
    15361 aaatgaccga aaacggcgtt aagtttcttg tagatgttga gaacggtcaa aagacaggtt
    15421 tttttctgga tcagaaggaa aaccgtgctg ccattgctcc attcgttaaa ggtgtcaaag
    15481 ttctggactg tttcacatat acaggttcct tcgcgttaca tgccggcctt tttggtgcgg
    15541 acagtgtttt gggtattgat atttcggaac atgcggtgaa gtgtgccgcc aaaaacgccg
    15601 aaataaacgg tctggacacc gtcgtgaaat ttcaggcagc aaacaccttt gatatattgc
    15661 gcgaatttta cgataagggt gaaacctttg atactattgt gcttgaccct cctgccttca
    15721 ccaaaaccaa aaatgcggtt cagggtgcta tcagaggtta caaggaaata aatcttcgcg
    15781 caatgaagat aattaaacga ggaggctatc tcattacgtg ctcctgttca cagcatgttg
    15841 attctgagct gtttatggac attttgtatg acgccgccga ctccaggcgc aaggtcaggg
    15901 ttgcagagta caggtcacag gccaaggatc atcctgtttt actggcatca cctgagaccg
    15961 gatatctgaa gtgtgcgatt ttacaagtag tttaaagtag tcttgcggta aattaagttt
    16021 tttaaacttg atctctttgg gcctgcacac tgtgcactga atccgagggg ccagagccca
    16081 ggcattttat tttttttgct aaaatcgcca tatccggtat ataaaatgat ttaatgaaaa
    16141 gaataatagc gggtgattac tatgctgcta ttatttataa cattacttgt gttaatcaaa
    16201 ttaactgaat taacttatag ggtattttat aaaagaaaaa taaatcaaat cttaaaagtt
    16261 ataaatacta aagaggattt gctatatcta aacttcaagg attatatgtc tgtcatcatg
    16321 gaagttctaa aacgtctggg atatagggtt aaacccactg ccgcttgcgg aatagacgga
    16381 agcggccttc tgttgaacaa tattcaattt accgaggtgt ggaaacatgg tcttcagcag
    16441 gttatagacg ttgaattagc catgaatctg ttcaaatgca tgagtgataa ctctatctac
    16501 agaggtatgc ttataacttt gggtgatttt aaatcatgta caaaagtata ctgccacaaa
    16561 aatgtaattg aatgcattaa cggtgatcag cttttggaca tgtgcaaatc agttcaaaat
    16621 gccaaaattg ttttggaacc tgcaaaatag gagctctccc caggaagtct cttcctcaaa
    16681 aaaattttta tttactcatg atcaatgttg attttacaaa tattcctgta tataattaaa
    16741 atatccaata aagtttatat tttgctttgc ataaatatgg cactggaact ttataataat
    16801 taaagactgg tattaattat ggtagatact tatagaattc ggaccaattc ttttttagac
    16861 agcaaagcaa cagattcgtt aatgcaattg gttaccaacg aaaaaaaaga aagaataaaa
    16921 aggtttgtac atagagaaga tgctctcagg tgcctgttgg gagatctact ttcccgttac
    16981 gcccttggta aaagaactgg gttaaaaaac agtgaactta aattcatggt aaatgaatat
    17041 aataagccat tattagtagc ccctgagcat ttacatttca atgtatccca ttccggcaac
    17101 tgggccgttt gtgctgtagc agacaagctt gtcggtatag acgttgaata tgttaaaaat
    17161 atagacctaa aaattgccga aagattcttc acaaattatg aatatgacag cctggtgaaa
    17221 caggatccaa aaaatcggat aagatatttt tacacactat ggacattaaa agaaagctat
    17281 ataaaagcag atggaagagg cctatcctta cctcttgact ctttttctat tgagataaat
    17341 aatgattcaa tctcagtcat taccgataac gagttaaaat catgtttctt tgaaatgtat
    17401 gaaattgata atttccacat ctcttcagtt tgctctttgg acagcagttt caataccact
    17461 ctaaaggaag tgacttattt tgatttatta caaaccttag cttaataata ttcagataaa
    17521 aatggactac atctataatt tgtacaaata caaaaaataa atctttacta acagcagtag
    17581 atgaaaaata ttaatcaata tttttcatct acttttaaat tttaaatatt tacttttatt
    17641 tgttaactgt atattatttc acgctctcag caataaattt aatcaattta taatatcaat
    17701 gaccataaat catcaattga atttaaaaac caggtatctg tcccattaaa tactttttaa
    17761 acatgaccat atcaagagta tcaacagacc cgcttgaatc cacatccgcc gcttttaatg
    17821 catcacccga caaaatggct tcatttagca gatgtttttt aaggagcgca tagtccaagg
    17881 catcaacctg cccgtcatta ttaatatctc cctttttaaa tatcggtgtg ataggaacag
    17941 ttgcaagata atcccttact gtagtatgtc gggaacttac atgattaacc agatcattca
    18001 cagcctggtt gaactgggtc tcgccatacg acaggaagct gtaattgctg ctttcccttt
    18061 cagctcccac cacatagggt cttacaagtt catgcagctg ccttattctg gatgttatag
    18121 ccgtctgatt gaagcaaccg ctcattgcgt tctgcatttc gttatggtat atattattat
    18181 aaaccggatc atccattaaa aagcggataa gaggccaatt attgccaatt tccctaagcg
    18241 agagacttgc aggtattccg ggcattggca tgccaaacgg attattattg agtgacatgt
    18301 taaagtcaca tggcaggtaa atcatccggc cgctattaga cagatcctgg tataagtaat
    18361 agtttttcgt cacccagcca tatgtatcaa cattaactgc agctgtattt atagccagcc
    18421 accgaaggaa cttgtttaca tcaaagactg attcaagtcc ggctctccaa cttgctgcat
    18481 ttgttcttgg tgcattgagc ttattaacca gtgcttgaag atcgctccaa tcgtttgctt
    18541 tttcattggt tttcttttca aagccctgtt ggttaaatgt ggtcaaatct gcacctgctc
    18601 ccgtttcccc cttatataaa ttacctttgg aattagggaa ctgtgtcttt agcatttcat
    18661 ccgccgggtc ctctgtcatt gtatataatc cccaatatac cggaccactg cccgtatcta
    18721 tatatactct gcaaaaagtg gatctagccg ctggtatacc tccgtcccgc agcatgtcac
    18781 taaatacttt atccctgaca aatgaaggat caaaccagtt attgctaaat gccagttctt
    18841 taaatccgta aaatttttga ttttttattt caggatattg atcttcaaat ttatcgaaat
    18901 tcaaacggaa cggaaactta tgttttccgc tcattttagg tgtgaacagt gtactttgcc
    18961 ctttgtacct tatacccaca ttccaccatg taatattgtt aaattttata gtagcaggta
    19021 cataaacggg gttttgagta cttgtcatgt ttaaattgtt aaggtctgtt tccattgtcc
    19081 tgtaattttc aggactgata gttatatcca tacgctgaac tttattatcc gggaatacca
    19141 cagtatagtt tccgtctaca tcaccatgag tctctttagt ccacccgtcc ggatgttgaa
    19201 cttcagctgc aaacacactg acctgtcccg atgaaacaac taaagccact gctagaataa
    19261 taatagatac tcttatcata ttagataatt tacacataat tttcattcct ttcgttttta
    19321 ggatatacac gcaataaaaa atcatcttta agatatatac ttaaatatca ttctcaggat
    19381 tggctaacaa aaactcatca taaaatgtat tgcaaatacg atgacaataa ttttattaca
    19441 tataaaatct attacttgat taactgacca ggcacaattc tgatttttac cacctccact
    19501 ttattacttt ctcttgactt accctatgga aaagaaatac ttactgctac ttttccgacc
    19561 accacctcca aatatatttt tccgtatacg tatatatttt ctgcactact ttgtaaataa
    19621 aagatatgta ttgcactaaa ttgtatattt ataccgttag tttgattata ttgtaccatt
    19681 attttacata taattcaata tttgtaatta tttagagctt tatttgaaaa taataccctc
    19741 tattgacaat gttattgctg gagacaaaat aaccggatgt cataaaattc taacatccgg
    19801 ttataaaaga aaatttccac taatttttta gataagccct atccgctatg acaatgttat
    19861 tataattttc taccataaac tatattgcta ttctccataa acatcaaact cacaatgacc
    19921 agcccagcct ccgtcaggca atccattgta aactatcttt acatatctgg ccttttcact
    19981 gaagctatcc tcccttatac gtgcactgct tgtttgtcct gtctgattca ctgccagtct
    20041 ccagttttgt ccgtcatctg agacctgaat aacatatagg taattgcctt cctcttcaaa
    20101 caccaccctg ctgccagtta ttgcatatat ctcaccaagg tcaacctgcc accagtgacc
    20161 tgcatgtgca tcattggcac accatctact gtatatatta ccgtcgtttc cttttaaagc
    20221 ggaataacct gttgattttt cactgtctga aacagcaggt ttcttcagcg ccagattatg
    20281 tcgcagatct gtattaattt ttttgtctgt attaaacaga gagcttattt gctcaacagt
    20341 aagttcctgt gaaggttcaa aacatgagct tcccatatat ttcaatatac tttgtcttag
    20401 ctgcctggca gcagggcgct tttcaagttc actttcaata tccatcgaac aaaccagcag
    20461 tttcccattg cctgcctttg cttcaaagag gtttgatatc ttgtgattat taaagaaatt
    20521 cggtataacc tgtattattg gttcatatcc ttcaggcatg ctatcgaggc aaacagatac
    20581 agagttttct aataaatcct tccattgata actggaatag aaat
//
