LOCUS       c00007_NZ_JHYD..       20718 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHYD01000010.1 Ruminiclostridium cellobioparum DSM 1351 = ATCC
            15832 T344DRAFT_scaffold00007.7_C, whole genome shotgun sequence.
ACCESSION   NZ_JHYD01000010
VERSION     NZ_JHYD01000010
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:33:25
            Original ID  :: NZ_JHYD01000010.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 29250
            Orig. end    :: 49968
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20718
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[39250:39968]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10718
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20718
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20718
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(278..1600)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     120; E-value: 1.8e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_28"
                     /transl_table=11
                     /translation="MLINKDLIIVGAGPAGLAAAVEARKRGIDDILVLEREPVAGGILN
                     QCIHDGFGLIKFNEALTGPEYAKKYMDEADGMGIELITNVMVQDLSSDKAVTTVSPDGI
                     RSYQAKAVILAMGCRERTRGAICIPGTRPAGVFTAGVAQNLVNIRNVMIGKNIIILGSG
                     DIGLIMARRLTLEGADVLAVVEKLPYSSGLQRNITQCLDDFGIPLLLSHTVTNIEGRER
                     VTAVTISRVDEKGNTIRGTSKKYDCDTLILSVGLIPENELSLNAGIEIDHVTGGPRVDE
                     KLQTSVPGIFACGNVLQVHDLVDYVSAEGELAAGSAAEYIGGGLGSSTADGCSSVDVGI
                     NSEDKGPNGENPLSYEKMAVRAGRGIRYVLPQTIRPGKAVTFSMRVVKPDREKTVCFIA
                     GDRIIKKRKYTALNPAEMIRMDLSQNELKDVSELEVCIYED"
     PFAM_domain     complement(707..1588)
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_28_0001"
                     /evalue="2.30E-33"
                     /label="ctg7_28"
                     /locus_tag="ctg7_28"
                     /protein_end="298"
                     /protein_start="4"
                     /score="115.8"
                     /tool="antismash"
                     /translation="KDLIIVGAGPAGLAAAVEARKRGIDDILVLEREPVAGGILNQCIH
                     DGFGLIKFNEALTGPEYAKKYMDEADGMGIELITNVMVQDLSSDKAVTTVSPDGIRSYQ
                     AKAVILAMGCRERTRGAICIPGTRPAGVFTAGVAQNLVNIRNVMIGKNIIILGSGDIGL
                     IMARRLTLEGADVLAVVEKLPYSSGLQRNITQCLDDFGIPLLLSHTVTNIEGRERVTAV
                     TISRVDEKGNTIRGTSKKYDCDTLILSVGLIPENELSLNAGIEIDHVTGGPRVDEKLQT
                     SVPGIFACGNVLQ"
     CDS             complement(1703..3169)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 156;
                     E-value: 2.6e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_29"
                     /transl_table=11
                     /translation="MTANTDNIFDIVIVGAGAVGCAVARELSGFDLKIAVLEKESDVAA
                     GTSGRNSAVVHAGFNNKPGSLMAKLCVEGNEGFEKVCSQLDVPYKKTGKLIVAFDESDF
                     AGIDQLMENGRKNGVKGLEFVDAHTVKKLEPHVGGIGAMLSPNTAITSPFIYTVALAEN
                     AAQNGVEFYFETEVNGISKRDGLFRLTAGKRHFFSRYIINSAGLYSDRIAALAGDKGYE
                     IHPCRGEYFILDKRTSQYLNMPVYPVPRPGLGGLGVHLTPTVEGNILIGPSAEYIKSKS
                     DYSATKGVMDQLFKEAKELLPALEMKHIIRSYTGIRSKLVGPKTGGYGDFIIEESGVVP
                     GLVNLIGIESPGLTASVPIGRMVRDIIAGREELVPKKDFIAERKGITPFRELTLEQKEK
                     LIKECPEYGEIVCRCEGITKKEILDAINNPLGVTTLAGIKYRARPMMGRCQGGYCLTRI
                     VDILKEQKGIEPEQVTLRGNNSKLFTGRVK"
     PFAM_domain     complement(1778..1942)
                     /aSDomain="Fer2_BFD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04324.17"
                     /description="BFD-like [2Fe-2S] binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_29_0003"
                     /evalue="8.50E-12"
                     /label="ctg7_29"
                     /locus_tag="ctg7_29"
                     /protein_end="464"
                     /protein_start="409"
                     /score="45.4"
                     /tool="antismash"
                     /translation="IVCRCEGITKKEILDAINNPLGVTTLAGIKYRARPMMGRCQGGYC
                     LTRIVDILKE"
     PFAM_domain     complement(2075..3142)
                     /aSDomain="DAO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01266.26"
                     /description="FAD dependent oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_29_0002"
                     /evalue="2.30E-73"
                     /label="ctg7_29"
                     /locus_tag="ctg7_29"
                     /protein_end="365"
                     /protein_start="9"
                     /score="247.9"
                     /tool="antismash"
                     /translation="DIVIVGAGAVGCAVARELSGFDLKIAVLEKESDVAAGTSGRNSAV
                     VHAGFNNKPGSLMAKLCVEGNEGFEKVCSQLDVPYKKTGKLIVAFDESDFAGIDQLMEN
                     GRKNGVKGLEFVDAHTVKKLEPHVGGIGAMLSPNTAITSPFIYTVALAENAAQNGVEFY
                     FETEVNGISKRDGLFRLTAGKRHFFSRYIINSAGLYSDRIAALAGDKGYEIHPCRGEYF
                     ILDKRTSQYLNMPVYPVPRPGLGGLGVHLTPTVEGNILIGPSAEYIKSKSDYSATKGVM
                     DQLFKEAKELLPALEMKHIIRSYTGIRSKLVGPKTGGYGDFIIEESGVVPGLVNLIGIE
                     SPGLTASVPIGRMVRD"
     CDS             3429..3698
                     /locus_tag="ctg7_30"
                     /transl_table=11
                     /translation="MCYNDINNSPERVMILYSLKEKYYDGQGILRNPGENYFDSEGILR
                     DPGDDYFDFMGILRQADEEFYDSQGILRNTDESFYDGSGNLIER"
     CDS             complement(3730..4659)
                     /locus_tag="ctg7_31"
                     /transl_table=11
                     /translation="MMDIFKTVNNEIVRINSFEEGSWINMVNPTEEEINSVNSALSVEI
                     DFLKAALDEEERARIESDSGQTLIIVDIPIVEKEGKLNVYTTIPLAIILIKHIIITVCL
                     KEDTLLSDFINNKVKSFLTQFKTRFVLQILYKNATRYLQYLKHIDKTSSRIEQEVYKSM
                     KNKEVIQMLKLEKSLVYFSTALKSNEVVLEKLMKYDHIKNYPEDTELLEDVIIENKQAI
                     EMANIYSSILSGTMDAFTSVISNNLNIVMKFLTSVTIVMAIPTMISSFFGMNVVIPLTS
                     HYAFFIIMGLSLAMCLVVGYTLYKKKLF"
     PFAM_domain     complement(3745..4599)
                     /aSDomain="CorA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01544.20"
                     /description="CorA-like Mg2+ transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_31_0004"
                     /evalue="7.20E-50"
                     /label="ctg7_31"
                     /locus_tag="ctg7_31"
                     /protein_end="305"
                     /protein_start="20"
                     /score="170.1"
                     /tool="antismash"
                     /translation="GSWINMVNPTEEEINSVNSALSVEIDFLKAALDEEERARIESDSG
                     QTLIIVDIPIVEKEGKLNVYTTIPLAIILIKHIIITVCLKEDTLLSDFINNKVKSFLTQ
                     FKTRFVLQILYKNATRYLQYLKHIDKTSSRIEQEVYKSMKNKEVIQMLKLEKSLVYFST
                     ALKSNEVVLEKLMKYDHIKNYPEDTELLEDVIIENKQAIEMANIYSSILSGTMDAFTSV
                     ISNNLNIVMKFLTSVTIVMAIPTMISSFFGMNVVIPLTSHYAFFIIMGLSLAMCLVVGY
                     TLYK"
     CDS             complement(5239..6045)
                     /locus_tag="ctg7_32"
                     /transl_table=11
                     /translation="MIKSIIRLLIFPVLALSILLSSCSYDSLNNKDKEKIEDYSKQILE
                     QASISISLMAEKVENQCYDIVLSKPVQERTEYTDDYDMLMNSRQISDSLVSKFMNNKDI
                     EMVFVEFNDGGIDGYRSTDYVDYEDVKEFVKPEKNGSVNWVPVKIKERNFVVLSKKITS
                     ITTADDIGEIYIVLKDSYFQASIKNISYGNHSRVFILDSDGKILSAAKSDSDNKIDGRE
                     LTEKIQNFRMNSGVFTAEIDKAENLVVYSKIKGRDWYVVGIIPAVN"
     CDS             6542..7198
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 177.1; E-value:
                     7.8e-54)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_33"
                     /transl_table=11
                     /translation="VSLLEFRNVTYIHSNNSILEDISLNIVQGDFVSITGPSGSGKSTI
                     LKLCSNLISPTEGDILFKAVNLNLYAPTELRKSITYCFQTPYLFGDTVIENIRFPFLIR
                     DLQIDDVRVNELFSKFQMPIEFLAKEVKNLSGGEKQRLSLIRSLLFKPEILLLDEITAA
                     LDVENTKIVEKVIKSLNNEGITVLWVTHNTEQSRKLANKRITIENGRVKNIELLG"
     PFAM_domain     6596..7027
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_33_0005"
                     /evalue="1.70E-29"
                     /label="ctg7_33"
                     /locus_tag="ctg7_33"
                     /protein_end="162"
                     /protein_start="18"
                     /score="103.2"
                     /tool="antismash"
                     /translation="LEDISLNIVQGDFVSITGPSGSGKSTILKLCSNLISPTEGDILFK
                     AVNLNLYAPTELRKSITYCFQTPYLFGDTVIENIRFPFLIRDLQIDDVRVNELFSKFQM
                     PIEFLAKEVKNLSGGEKQRLSLIRSLLFKPEILLLDEITA"
     CDS             complement(7277..7561)
                     /locus_tag="ctg7_34"
                     /transl_table=11
                     /translation="MKEDIIRFLDDEQKIKIWPSKVEKKIQILEYLATKFEYGKIYSEK
                     EVNTIIEDWHSFNDYFLLRRALVDYKLLCRTRNGAQYWRESAISNVFPC"
     PFAM_domain     complement(7310..7519)
                     /aSDomain="DUF2087"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09860.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2087)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_34_0006"
                     /evalue="1.20E-26"
                     /label="ctg7_34"
                     /locus_tag="ctg7_34"
                     /protein_end="84"
                     /protein_start="14"
                     /score="92.7"
                     /tool="antismash"
                     /translation="IKIWPSKVEKKIQILEYLATKFEYGKIYSEKEVNTIIEDWHSFND
                     YFLLRRALVDYKLLCRTRNGAQYWR"
     CDS             complement(7558..8328)
                     /locus_tag="ctg7_35"
                     /transl_table=11
                     /translation="MANDFINMTLEEIKNGYHFDTVKNCYICNICGKEFGIGEIFQSGN
                     RFFNADRMINIHVTEEHPDLLELLTSYNKKYTGITDNQKEILEMMYQSMTDNEIAKKTG
                     VAAATIRHQRFVFREKAKQAKLYLAIYELALRGLDKGRIRAESTDEIIDIHEGARMIDD
                     RYMVTKAEEDKILEAMFTSLSPLKLKVISSKEKKKIVILKKISQQFERNKHYSEKEVNG
                     ILKQIHEDFATLRRYLIEYGFMERTNDCKEYWLK"
     PFAM_domain     complement(7567..7770)
                     /aSDomain="DUF2087"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09860.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2087)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_35_0007"
                     /evalue="2.30E-27"
                     /label="ctg7_35"
                     /locus_tag="ctg7_35"
                     /protein_end="254"
                     /protein_start="186"
                     /score="95.0"
                     /tool="antismash"
                     /translation="KLKVISSKEKKKIVILKKISQQFERNKHYSEKEVNGILKQIHEDF
                     ATLRRYLIEYGFMERTNDCKEYW"
     CDS             8675..9979
                     /locus_tag="ctg7_36"
                     /transl_table=11
                     /translation="VLIQLMVVNTLFAMITGYLVHYFLKTNFNIRSAKTRLVVFIICFG
                     ISNGLLSTLCMKYLPGNLQFLKSFFLLILSIIVIKYLLKISIIRALLSFCTIMLAVMLC
                     NFFAPLVFAFFSNVNVTPDVITNDVFLFAVMNALVYFFTSIIILLTPFAKKLGQFKNLK
                     PVIILLFITLLMLVLNAGVHYIVSFDPISFTATLILSLIYLIVSVWYINNFYKYEMKIE
                     EEKQQAFYNESLSLVIQDLRRFKHDQANHLTVISAMLKMKKFDQANSYISEIFNTTESI
                     VDTSVCDIKNAGLFGLISSKMDYAKKTGIKFNLQAIGEIDSIPNVKISELCEIIGIYLD
                     NAIEAAAISGDKEVEMRLENKEESIDIVIDNSCSIIPNLESIRQDGYSTKGTNRGHGLS
                     IVDKILSKYASISNTINFDNKSMIFTQILKIKKGI"
     PFAM_domain     9368..9514
                     /aSDomain="SPOB_a"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14689.8"
                     /description="Sensor_kinase_SpoOB-type, alpha-helical
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_36_0008"
                     /evalue="1.80E-08"
                     /label="ctg7_36"
                     /locus_tag="ctg7_36"
                     /protein_end="280"
                     /protein_start="231"
                     /score="34.0"
                     /tool="antismash"
                     /translation="ESLSLVIQDLRRFKHDQANHLTVISAMLKMKKFDQANSYISEIFN
                     TTES"
     PFAM_domain     9659..9958
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_36_0009"
                     /evalue="7.60E-13"
                     /label="ctg7_36"
                     /locus_tag="ctg7_36"
                     /protein_end="428"
                     /protein_start="328"
                     /score="48.3"
                     /tool="antismash"
                     /translation="SELCEIIGIYLDNAIEAAAISGDKEVEMRLENKEESIDIVIDNSC
                     SIIPNLESIRQDGYSTKGTNRGHGLSIVDKILSKYASISNTINFDNKSMIFTQIL"
     CDS             complement(10001..10138)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_37"
                     /sec_met_domain="TIGR04223 (E-value: 1.6e-08, bitscore:
                     28.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKGKIRLMVMTVLSMVGIIAATSSAGACWFSSFYQQECPKSLLK
                     "
     aSDomain        complement(10004..10114)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg7_37_0001"
                     /evalue="3.20E-07"
                     /identifier="TIGR04223"
                     /label="ctg7_37"
                     /locus_tag="ctg7_37"
                     /protein_end="45"
                     /protein_start="8"
                     /score="28.3"
                     /tool="antismash"
                     /translation="MVMTVLSMVGIIAATSSAGACWFSSFYQQECPKSLLK"
     CDS             complement(10125..10718)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_38"
                     /sec_met_domain="AgrB (E-value: 1.4e-38, bitscore: 125.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSKITKKITNEILITVPGITEEKAEEIDYGLYMAFSDGLKLIAV
                     LLTAFALGQLRYALVAVAVFSVNKSYFGGIHAKTQLGCIITHFTFIFGTIYLSHIIAFN
                     YLNIILFIISGVLVYLYAPADLISKPIITEKRRKELRIKSSVVFIICFVISFFVPKDFS
                     NVMSIITLINAVNLTPVVYKITKNRKGGVLNEKR"
     PFAM_domain     complement(10203..10706)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_38_0010"
                     /evalue="1.30E-36"
                     /label="ctg7_38"
                     /locus_tag="ctg7_38"
                     /protein_end="172"
                     /protein_start="4"
                     /score="125.8"
                     /tool="antismash"
                     /translation="ITKKITNEILITVPGITEEKAEEIDYGLYMAFSDGLKLIAVLLTA
                     FALGQLRYALVAVAVFSVNKSYFGGIHAKTQLGCIITHFTFIFGTIYLSHIIAFNYLNI
                     ILFIISGVLVYLYAPADLISKPIITEKRRKELRIKSSVVFIICFVISFFVPKDFSNVMS
                     IITLI"
     CDS             complement(10914..11033)
                     /locus_tag="ctg7_39"
                     /transl_table=11
                     /translation="MTRFYLEKLKNVEAPLENSLIRWWHYALAAAAIAAVILL"
     CDS             complement(11386..12513)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 356.6; E-value:
                     1.9e-108)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_40"
                     /transl_table=11
                     /translation="MKAIVYEGIKNVKVKNIGDPQIRNDDDIIVKVTSTAICGSDLHLI
                     HGMVPNMPFGFVLGHETMGIVVEAGKGVHKVKKGDRIIVPFPISCGHCWYCEHDLWSQC
                     DNSNANGETGAIFGYSKTYGGYDGGQAEYLRVPYANVGPVQVPDDLTDEQVLFLTDILP
                     TSYWGVENGGVKKGDTVVVLGCGPVGLLSVKWAFFHGADRVIAVDYIDYRLQHAAKYGA
                     EVINFEEHENTGEYIKEITHGGADVVIDCVGMDGKMTTFEIIETAMKLQGGSKSAIELA
                     TQAVRKGGTVSMVGVYGARYNMFPLGDFFSRNITLKMGQCPAHTYVDRILKLIGEGKFD
                     ATDIITHKLSLDMGEHGYKIFDKKEDHCIKVILKP"
     PFAM_domain     complement(11752..11955)
                     /aSDomain="ADH_zinc_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00107.28"
                     /description="Zinc-binding dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_40_0013"
                     /evalue="8.40E-13"
                     /label="ctg7_40"
                     /locus_tag="ctg7_40"
                     /protein_end="254"
                     /protein_start="186"
                     /score="48.6"
                     /tool="antismash"
                     /translation="PVGLLSVKWAFFHGADRVIAVDYIDYRLQHAAKYGAEVINFEEHE
                     NTGEYIKEITHGGADVVIDCVGM"
     PFAM_domain     complement(12088..12438)
                     /aSDomain="ADH_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08240.14"
                     /description="Alcohol dehydrogenase GroES-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_40_0012"
                     /evalue="4.50E-29"
                     /label="ctg7_40"
                     /locus_tag="ctg7_40"
                     /protein_end="142"
                     /protein_start="25"
                     /score="100.6"
                     /tool="antismash"
                     /translation="DDIIVKVTSTAICGSDLHLIHGMVPNMPFGFVLGHETMGIVVEAG
                     KGVHKVKKGDRIIVPFPISCGHCWYCEHDLWSQCDNSNANGETGAIFGYSKTYGGYDGG
                     QAEYLRVPYANVG"
     PFAM_domain     complement(12448..12513)
                     /aSDomain="ADH_N_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13823.8"
                     /description="Alcohol dehydrogenase GroES-associated"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_40_0011"
                     /evalue="2.40E-07"
                     /label="ctg7_40"
                     /locus_tag="ctg7_40"
                     /protein_end="22"
                     /protein_start="0"
                     /score="30.6"
                     /tool="antismash"
                     /translation="MKAIVYEGIKNVKVKNIGDPQI"
     PFAM_domain     12650..13192
                     /aSDomain="Mn_catalase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05067.14"
                     /description="Manganese containing catalase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_41_0014"
                     /evalue="2.90E-55"
                     /label="ctg7_41"
                     /locus_tag="ctg7_41"
                     /protein_end="181"
                     /protein_start="0"
                     /score="187.4"
                     /tool="antismash"
                     /translation="MFKHDKALLHEVKVDGPNPAYAAMMQEQLGGPHGELKAALQYLSQ
                     SFRIKDPQIKDLFLDIASEELSHMEMVATTINLLNGHVLDAKNATIGNIQAHVSTGLTP
                     ALTSASGQYWTAAYIEETGDLAADILSNISAEQRAKVVYEYLYRQIPDKGVRQTIDFLL
                     NREEAHNTMFREAFNRIQ"
     CDS             12650..13339
                     /locus_tag="ctg7_41"
                     /transl_table=11
                     /translation="MFKHDKALLHEVKVDGPNPAYAAMMQEQLGGPHGELKAALQYLSQ
                     SFRIKDPQIKDLFLDIASEELSHMEMVATTINLLNGHVLDAKNATIGNIQAHVSTGLTP
                     ALTSASGQYWTAAYIEETGDLAADILSNISAEQRAKVVYEYLYRQIPDKGVRQTIDFLL
                     NREEAHNTMFREAFNRIQYTGSLRDWGITQDSKLYFNLSTPGDQFFNANNPNPASFNAP
                     NGGSPAN"
     CDS             complement(13486..13929)
                     /locus_tag="ctg7_42"
                     /transl_table=11
                     /translation="LFAGKDSTIQTAADLKGRKFAGPVAYNMAKDGYRVVTTGKDLVDA
                     TIVVATSGAFYEKNPLLVKRFLEAQSEIAQYMKENAEETLEITARETELSMEAVKEMFP
                     MYDFSTEITEADITSMKKTEQFMKDNGMIENRVDINGLILKID"
     CDS             complement(14241..14534)
                     /locus_tag="ctg7_43"
                     /transl_table=11
                     /translation="MKRNDIGLDDLLAEFNENIIGKPSSATLGIVTITRRDLEELKTSN
                     KKANIKMTGILAFSEDVTPDLAKETIESVKVRGTIKASPHVQEVLNTLINET"
     PFAM_domain     complement(14274..14465)
                     /aSDomain="RHH_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17723.3"
                     /description="Ribbon-Helix-Helix transcriptional regulator
                     family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_43_0015"
                     /evalue="5.50E-16"
                     /label="ctg7_43"
                     /locus_tag="ctg7_43"
                     /protein_end="87"
                     /protein_start="23"
                     /score="58.8"
                     /tool="antismash"
                     /translation="SSATLGIVTITRRDLEELKTSNKKANIKMTGILAFSEDVTPDLAK
                     ETIESVKVRGTIKASPHVQ"
     CDS             complement(14629..15288)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 78; E-value: 2.1e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_44"
                     /transl_table=11
                     /translation="MPRNKYPEETEQIILDAALKLFIENGYEQTTILDIVDEMGGLTRG
                     AFYHHFKTKEEVFFALTDKLFNDIDPFTKIKVRTDINGLEKIKLTLQILNESKEYAVLH
                     LQILPLIESSPIAFKIYMEKQRTFLASKYAELIEEGINDGSIKAKYPKLTAELFLLICN
                     VWMMPTIYPQSNEEEAWQRFNMAKDIVDFLGLPVLDKTLTSHVVINDQGIVVEIKK"
     PFAM_domain     complement(15106..15249)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_44_0016"
                     /evalue="2.30E-15"
                     /label="ctg7_44"
                     /locus_tag="ctg7_44"
                     /protein_end="61"
                     /protein_start="13"
                     /score="56.2"
                     /tool="antismash"
                     /translation="ILDAALKLFIENGYEQTTILDIVDEMGGLTRGAFYHHFKTKEEVF
                     FAL"
     CDS             complement(15641..16153)
                     /locus_tag="ctg7_45"
                     /transl_table=11
                     /translation="MVVFGTYQIFQLLTQQKIEIPAVHLARYGEGMNKKGYTVKFKTRM
                     HFKDKKSRYPSGFGELPPLTELMIVPIVAVKCMFIAATTANANRNIFALNTAKCQLESS
                     APRSTVNAEVVMVLAADMLKTIAEYSKSDRAEFIRTVQEAQNARQTTNVTKQKKRLAIA
                     RKKSCRA"
     CDS             complement(16468..18276)
                     /locus_tag="ctg7_46"
                     /transl_table=11
                     /translation="MKSYLGLIPISAKVHKRQNRMTLLCIIFAVFLVTAIFSMADMGVR
                     MEQTRLLDKHGSSLTFQDLLSSTLAQTLFLAAAVLFVLILVAGVLMISSSLNSNVAQRT
                     KFFGMMRCIGMSKRQIIRFVRLEALNWCKTAVPIGVVLGIAITWGLCAALRFLVGEEFS
                     EIPLFGISLIGIISGIVVGIVTVIIAASSPAKRAAKVSPITAVSGNSENAKILTHAANT
                     RFSKIETALGVHHAVSGKKNLVLMISSFALSIILFLSFSVLIQFIGYLMPQSSNASDID
                     ISSSDGSNSIDSAMLTEISTMQGVKSVFGRRSLFDIPAEIRNDNQLTSTVDMISFDEFD
                     LDCLTKDKLLRKGSDISKVYGDSNYVLAICDTNSPLEIGDKIQIGNGELEIAGLLKYDP
                     FNSDGSANGQITIITSGETFIRLTGINGYSLIMIQAPKTVTDEDIAAISSVLDENCTLQ
                     DRREQSTAGTYMAFQICIYGFLVIITLVTVLNIMNSISMSVSARINQYGAMRAIGMDTH
                     QVTKMIAAEAFTYALSGCVVGCAVGLLVSKFLYDTLITAHFSYATWSVPIVPLVIILLF
                     VFVAAIVAVYKPSKHIQNIVLTAIFS"
     PFAM_domain     complement(16504..16764)
                     /aSDomain="FtsX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02687.23"
                     /description="FtsX-like permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_46_0018"
                     /evalue="1.30E-13"
                     /label="ctg7_46"
                     /locus_tag="ctg7_46"
                     /protein_end="591"
                     /protein_start="504"
                     /score="51.3"
                     /tool="antismash"
                     /translation="QYGAMRAIGMDTHQVTKMIAAEAFTYALSGCVVGCAVGLLVSKFL
                     YDTLITAHFSYATWSVPIVPLVIILLFVFVAAIVAVYKPSKH"
     PFAM_domain     complement(17671..17964)
                     /aSDomain="FtsX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02687.23"
                     /description="FtsX-like permease family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_46_0017"
                     /evalue="1.80E-08"
                     /label="ctg7_46"
                     /locus_tag="ctg7_46"
                     /protein_end="202"
                     /protein_start="104"
                     /score="34.8"
                     /tool="antismash"
                     /translation="KFFGMMRCIGMSKRQIIRFVRLEALNWCKTAVPIGVVLGIAITWG
                     LCAALRFLVGEEFSEIPLFGISLIGIISGIVVGIVTVIIAASSPAKRAAKVSP"
     CDS             complement(18273..18956)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 210.4; E-value:
                     4.9e-64)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_47"
                     /transl_table=11
                     /translation="MNLLEVNALCKTYGNGDTAVKALKDVSFSVPKGQFVAVVGESGSG
                     KSTLLNMLGALDTPTSGNVRIDGNDIFRMKDEKLTIFRRRNIGFIFQAFNLIPELNVEQ
                     NITFPVLLDYKNPDKAYVEEILTVLSLQDRRGHLPRQLSGGQQQRVAIGRALITRPMLI
                     LADEPTGNLDSNNSSEVISLLKTASKRYSQTIIMITHSRSVASTADRVLQVSDGVLSDF
                     GGYTE"
     PFAM_domain     complement(18450..18890)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg7_47_0019"
                     /evalue="9.30E-34"
                     /label="ctg7_47"
                     /locus_tag="ctg7_47"
                     /protein_end="169"
                     /protein_start="22"
                     /score="117.0"
                     /tool="antismash"
                     /translation="LKDVSFSVPKGQFVAVVGESGSGKSTLLNMLGALDTPTSGNVRID
                     GNDIFRMKDEKLTIFRRRNIGFIFQAFNLIPELNVEQNITFPVLLDYKNPDKAYVEEIL
                     TVLSLQDRRGHLPRQLSGGQQQRVAIGRALITRPMLILADEPT"
ORIGIN
        1 aggggcagtc agttcaagaa ccctgagcgt atcaacggct tcctgcagtt tttccctcgg
       61 tatgggcttg ctgcttctga cacttaccag cggatgtgtt ccgcccttta cttttacagt
      121 ggaggtcaag cttctctttg ggcactgtac ttcgtcttca gcgtatgtcc ttccatttct
      181 gcataatgcg ttttcaacac gggtgaccct gttttgctca tcgacaaaaa cattcagcct
      241 gcagccattg ggacatacaa tgcacaccat ttccctgtta gtcttcatat atgcatacct
      301 ccagttccga aacgtccttc agttcatttt ggcttaagtc catacgtatc atttcggcag
      361 gattcaaggc tgtatatttc cttttcttta tgatcctgtc accggctata aaacagactg
      421 tcttttccct gtcaggcttt accactctca tggaaaaggt tactgctttg ccgggcctta
      481 ttgtctgggg caatacatat ctgatacccc ggcctgccct caccgccatt ttctcatagg
      541 atagcggatt ttcaccattt gggcccttat cctcagaatt tatacctaca tctacactgc
      601 tacagccgtc tgccgtgctg cttccgagac cgcccccgat atattcagca gccgaaccgg
      661 ccgccagctc tccctccgcc gatacgtaat ccaccaggtc atgcacctgg agtacatttc
      721 cgcaggcaaa tattccggga acactggtct gaagcttttc atccacacgc ggaccgcctg
      781 tcacatggtc aatttctatt ccggcattca gtgataattc attctcggga atgaggccca
      841 ccgaaagtat caaggtgtcg caatcatatt tttttgaagt gccccggatg gtattgccct
      901 tctcatcaac cctggatatt gtaactgctg tcactctctc cctgccttct atattggtaa
      961 ccgtatggct gagcagcagc ggaatcccga aatcatcaag gcattgggta atattccttt
     1021 gaagtccgct ggaataaggc agcttttcca ctaccgccag aacatcggca ccctcaagcg
     1081 taagccttct ggccataatg agccctatat cgcccgaacc caatattatt atgttttttc
     1141 cgatcatgac attcctgatg tttacaagat tttgagccac accggccgta aacaccccgg
     1201 caggcctggt gccaggaatg catatggctc ctctggttct ctccctgcag cccatggcaa
     1261 gaataacggc ttttgcctga tagcttctta ttccgtcagg gctgacggtg gtcacagctt
     1321 tatcactgct gagatcctgc accattacgt tggtaatgag ctctataccc attccatccg
     1381 cttcatccat atattttttg gcatattccg gcccggtcag cgcctcattg aactttataa
     1441 gcccgaagcc gtcatgaatg cattgattta agatccctcc cgctaccggt tctctctcca
     1501 gaaccagtat atcgtcaata cctcttttcc tggcttcaac tgctgccgcc agaccggccg
     1561 gaccggcgcc gactattatc aaatccttat ttatcaacat attaactatc attcctttcg
     1621 ctgtgctcaa ggcacaaaaa gtgatgaaaa actcctcact cctcatccgc tataagacga
     1681 ataaaagagg ttaatcggcc gtttatttga cccgtccggt aaacagcttt gagttatttc
     1741 ccctcaaggt aacctgttcc ggctcaatcc ccttttgctc cttcagaata tcaacaatcc
     1801 ttgtaaggca gtagccgccc tggcatcttc ccatcatggg ccttgccctg tatttgatac
     1861 ctgccagggt agtcactccc agaggattgt tgattgcgtc cagtatctcc ttctttgtta
     1921 tgccctcaca tctgcaaaca atttctccgt attccggaca ctcttttatg agtttttcct
     1981 tctgttccag cgtcagttcc cggaagggcg ttataccttt tctttcggca ataaaatcct
     2041 ttttaggaac aagttcctcc ctgccggcga ttatatctct taccatcctg ccgatgggca
     2101 ctgaagctgt caaaccgggg gactcgatac cgataagatt tacaagcccc ggaacaacgc
     2161 cggattcctc tataataaag tccccgtagc cgccggtttt tggtcccacc aatttcgatc
     2221 ttatacctgt atagctcctg atgatgtgct tcatttcaag ggcaggaagc agttccttag
     2281 cctctttgaa caactggtcc atcacacctt ttgtagcgct gtaatcgctc tttgatttta
     2341 tatattcggc acttgggcct attagtatgt ttccttcgac tgtaggtgtg agatgcacgc
     2401 ccagtccgcc cagccccggc cttggaacgg ggtataccgg catgttaaga tactggctgg
     2461 tccttttgtc caatatgaaa tattctccgc ggcaggggtg gatttcataa cccttgtcgc
     2521 ctgcaagcgc ggctatcctg tcagagtaga gcccggcact gtttattatg tacctgctga
     2581 aaaaatgtct ttttccggcg gtcagcctga ataaaccgtc cctctttgat atgccgttca
     2641 cttctgtctc aaagtagaat tcaactccgt tttgggcggc attttcggcc agcgccacag
     2701 tatatataaa agggcttgtt atggcagtgt tgggggacag catggcgccg attccgccaa
     2761 catgcggctc cagcttttta acggtatgtg catccacgaa ttcaagccct tttacaccgt
     2821 ttttgcggcc gttctccatc aattgatcaa tgccggcaaa atcgctctca tcgaaggcaa
     2881 cgattagctt tccggtcttc ttataaggta cgtccagctg ggaacaaact ttttcaaagc
     2941 cttcgttgcc ttccacgcaa agcttggcca tcaggcttcc gggcttgttg ttgaagccgg
     3001 catgtaccac tgcactgttc cggccgctgg ttcctgctgc aacatcgctt tccttttcaa
     3061 gtacggctat tttcaaatca aatcctgaca gttctctggc aactgcacaa ccgacagctc
     3121 ccgctccaac aatgactata tcgaatatat tatctgtatt tgcagtcata ctacctccaa
     3181 aagcgatgtt tgtttattgt atttttattg tatttagaat ttatctgctc tatcgctttg
     3241 ctataccaaa aacttttatt tgattatagc acaacggctg ctgtaatcaa gcttttgaac
     3301 ctctattaaa taaaatttaa taaagccggg caggaagaat ataaaggacc ggtaccggtt
     3361 aaaagcggcc ggcagtctgg taatttaagt taataaataa tgaaaatacc ttttctgtta
     3421 ctgttaatat gtgttataat gatatcaata attctccaga aagagtgatg attttgtatt
     3481 cccttaagga aaaatactat gatggtcaag gtattttgcg gaatcccggc gaaaactact
     3541 ttgacagtga aggtatttta cgcgaccccg gtgatgatta ttttgacttt atgggtattt
     3601 taaggcaggc tgatgaagaa ttctacgaca gccagggcat tttaagaaac actgatgaaa
     3661 gtttttatga cggctcagga aatttaatag aaagataaaa agtgcccttt cattgggcac
     3721 ttttgttttc taaaataatt tctttttata cagcgtataa cctacaacaa gacacatagc
     3781 cagggataaa cccattatta tgaaaaatgc ataatggctt gtcagcggaa taaccacatt
     3841 cattccgaaa aagcttgaaa tcattgtcgg tatggccata acaatggtaa ccgaagtcag
     3901 aaatttcata actatattca ggttatttga tatgaccgag gtaaaggcat ccattgtgcc
     3961 tgacaaaatg ctgctgtata tgttagccat ctcgatggcc tgtttgtttt caataatgac
     4021 atcctcaaga agttcggtgt cctcgggata gttttttata tgatcgtact tcattaattt
     4081 ttcaagaaca acttcattgg attttaaagc ggttgaaaag tacacaaggc tcttttccag
     4141 tttaagcatc tggatgactt ccttgttttt cattgacttg tacacttcct gttctatcct
     4201 gctgctggtt ttgtctatgt gcttcaggta ttgaagatac cttgtggcat tcttgtacag
     4261 tatttgaagt acaaatctgg tcttaaactg ggtcaaaaag gatttaacct tattgttgat
     4321 aaaatcgctt aaaagagtat cctccttcag gcaaacagtt attatgatat gctttataag
     4381 tatgattgcc agaggaatgg ttgtataaac attcaatttt ccttcttttt caactatggg
     4441 tatatcaaca attataagag tttgtccgct gtcgctctca atacgtgctc tttcctcttc
     4501 atccagtgct gctttcagaa aatcgatttc aacgctcaat gcactgttaa cactattgat
     4561 ctcttcctcg gtggggttca ccatgttgat ccaggagccc tcttcaaatg aatttatccg
     4621 tactatttca ttgtttacag tcttaaaaat atccatcatt tgtctcaccc tcttttaata
     4681 tttttaggaa caagggttga ttttccagac tataaaatca tagtatcaga acacttaaag
     4741 acatgcaaag acatgacggc atggaaaata aacccaagta aggtttttat taaattttaa
     4801 gttgctactg tcagggtcac aatccatacc attcacctac ctttacaaaa tgataaaaaa
     4861 caataaaaaa accgacacta cgagtgacgg attttaagca taaaaaaaca ccttcactcg
     4921 ttgagtttta gcactataca gcttaggaaa aacaaatcca gctacattaa gtaaaacctt
     4981 atttcggtag tacctgttga cccattggca tctctcgatg tttccgggca gcagcatata
     5041 tctgtatagg aacctcacct aacgaattat tctattagca tactaattat atacctataa
     5101 ttcttatatt tcaatacgtt gacgcagaaa attatttata aaaatgtcgc tttaaaacac
     5161 gttgaattgt actatttgcc aaattcacag tcggatgccc tccctgagtt catttcacgg
     5221 gcgaacttta cccttttatt aattaactgc aggaattata ccaacaacat accagtctct
     5281 gccttttatt ttagaataaa caacaagatt ttcagcttta tcaatctctg cagtgaacac
     5341 acctgaattc atcctgaaat tttgaatctt ttcggttaat tctctgccgt ctattttatt
     5401 atcagaatca gactttgcag cagaaagtat ttttccatca gagtctaaaa taaatactct
     5461 cgaatggtta ccataagata tgttttttat tgaagcttga aaataactat cttttaatac
     5521 aatataaatt tcgccgatat cgtcagcagt tgttatgctt gttatttttt tacttaatac
     5581 tacaaagttt ctttccttga tttttacagg tacccaatta actgatccat ttttttcagg
     5641 tttcacaaac tctttcacat cttcataatc cacataatca gtagatctat agccgtctat
     5701 tcctccatcg ttaaattcaa caaataccat ttcaatatct ttattattca taaatttgct
     5761 aacaagtgaa tcggatattt ggcgtgaatt cattaacata tcataatcat ctgtgtattc
     5821 tgttctttcc tgtaccggtt tagagagaac tatatcataa cactggtttt caactttttc
     5881 ggccattaat gaaatgctga tgcttgcctg ctccaatatt tgttttgagt aatcttcaat
     5941 tttttcttta tccttattat taagtgaatc ataagagcag gagcttagca gaatgcttag
     6001 agccagcaca ggaaatatca gtaatcttat tattgattta atcattgtac cctctttatt
     6061 ttaaagtagt tttatataat tctttaacat ttttgcactt ttattacaat atatttaatt
     6121 ataggacaaa tattgcaaaa tgtatactat ttaatccggc ctaagacata tttcacacat
     6181 tcatcatttt cagccggtac gggcgaatat aaaaggctct gcatatttac ctcctctata
     6241 gagattatac caattacagt tcaggtcttt gttcaagtgt tagttgttcc ctgccttctg
     6301 atgccggttc tgcctgactt gttaccggcc actaaagtaa ttattaaaaa ttttaaaatt
     6361 aacttaatca ttaatatagc acctcaatat ccttgcttca atataaaata actgttaaac
     6421 aaacataaat gttaataata tacatattgc acattatctt gcattgcttg ccaacagctt
     6481 gattatagct gtgatatatg ggaatataat aaaaggtaca catttatgga ggtgctgaac
     6541 cgtgtcctta cttgaattcc gcaatgtaac ttatattcat tccaataatt ccatattgga
     6601 agacatatct ctgaatattg tacagggaga ttttgtttca attacaggtc cttccggaag
     6661 cggtaaaagt acaattttaa aactttgcag caacctgata agccctacgg aaggtgacat
     6721 actgtttaag gctgttaacc tgaacctgta cgccccaaca gaattaagaa aaagcataac
     6781 ctattgtttt cagacaccct acctgttcgg cgatactgtt attgaaaata tccgttttcc
     6841 ttttttaata agagatttac aaattgatga tgtgagagtc aatgaattat tctcaaaatt
     6901 tcaaatgccc atagaattcc tggcaaaaga agttaaaaac ctatccggag gagaaaagca
     6961 aagattgtcg ttgatcagaa gtctgctgtt caaaccggaa attttgttgc tggatgaaat
     7021 tacagcagcg cttgatgttg aaaatacaaa aattgtagaa aaagtaataa aatcgctgaa
     7081 taatgaaggt ataacagtgt tatgggtaac acacaacact gagcagagca gaaagttagc
     7141 aaacaagcga ataacaatag aaaatggcag ggttaaaaat atagaactgc tgggttgatt
     7201 ttttatgcta aaaaatctct ttccgccgct tccatttcat catttatcgc atgttatccg
     7261 gcatatagag gatttttcaa caggggaaaa catttgatat agctgattcc ctccaatatt
     7321 gcgctccgtt tctggtacgg catagcagtt tataatcaac cagagccctt ctcagcagaa
     7381 aatagtcgtt aaatgaatgc caatcttcta taatggtatt tacttctttt tcggaatata
     7441 tttttccgta ttcaaacttg gtggccaggt actcaagtat ctgaattttc ttttctactt
     7501 tggaaggcca tatttttatt ttttgctcat catctaaaaa tcttataata tcttctttca
     7561 ttttaaccaa tactccttac agtcatttgt ccgttccata aatccatatt ctataagata
     7621 acgtctcaag gtagcaaaat cctcatgtat ttgcttcaat ataccattta cttctttttc
     7681 tgaataatgc ttattccttt caaattgttg ggatattttt ttcaaaataa caattttctt
     7741 tttttcctta ctggagatta ctttcagttt aagaggcgac aaagaggtaa acatggcctc
     7801 aagaattttg tcctcctctg cctttgttac catatatctg tcgtcgatca ttctggcccc
     7861 ctcatgaata tcaataattt cgtcagtgct ttctgcacgt attctccctt tatccaatcc
     7921 tcttagagcc agttcgtata tggccagata gagctttgcc tgcttcgctt tttcccgaaa
     7981 aacaaatctt tgatgtcgaa ttgtggcagc tgccacacct gtctttttgg ctatttcatt
     8041 atctgtcata ctctggtaca tcatctcaag gatttccttt tgattatcag taattcccgt
     8101 atactttttg ttgtatgagg tcagcagctc cagcaaatcg ggatgctctt ccgtcacatg
     8161 gatatttatc attctatctg cattaaaaaa cctgttccca gactgaaaga tctctccaat
     8221 cccgaattcc ttcccgcata tattacatat gtagcagttt tttacagtat caaagtgata
     8281 tccatttttt atttcttcca gagtcatatt tataaagtca ttggccattt aaacaatacc
     8341 gccttttgtt tattaattat ataaacatat attattatcg tttaataggt ttgtcaaggt
     8401 taattttttt gtcgaaaata gataaaaaaa atcaattgta tttcatggtg aatattgtta
     8461 ttttagctta tatgatataa aatatttata tagtatagta aaaatatggg aaatatatat
     8521 aatcaatgca tcatcaacgc agaataattt ctttaaatgc atggactcat ttaaaggtaa
     8581 cattaatgta catttttaat aaaaacttta cattaattac ttatatgcaa ttcaggtatt
     8641 agaaataaaa taaaaatagt taggagacaa atttgtgtta attcagttga tggttgttaa
     8701 tacacttttt gcaatgatta ccggttattt ggtacattat tttttaaaaa caaattttaa
     8761 tatcaggtca gcgaagacca gacttgtagt attcattatt tgttttggta tttcaaacgg
     8821 tcttttatca actctttgta tgaaatacct tccgggtaac ctgcagtttt tgaaatcctt
     8881 ttttctatta atactcagca ttatagttat taaatattta cttaaaatca gtataataag
     8941 agctttgctg tcattttgca caattatgct ggcagtgatg ctttgtaatt tctttgcacc
     9001 attggttttt gcatttttct caaatgtgaa tgtcactccc gatgtaataa caaatgacgt
     9061 ctttctgttt gctgttatga atgcgctggt ttattttttt acatcaatta ttattctgct
     9121 tactcccttt gcaaaaaagc tgggacagtt taaaaatcta aagcctgtta ttatcctgtt
     9181 atttattaca ctgctgatgc ttgtattaaa tgccggagtc cactatatag tcagctttga
     9241 tcccatatcc tttactgcca cactcatatt gtccttgatt tatttaatcg tttctgtctg
     9301 gtacataaac aatttctaca aatatgaaat gaaaatagag gaagaaaaac aacaggcttt
     9361 ttacaatgaa tctctaagtc tggtaataca ggatttaaga aggttcaaac atgaccaggc
     9421 caaccatttg acagttatct ccgcaatgtt gaaaatgaaa aaattcgatc aggcaaattc
     9481 atacataagt gaaatattta atacaactga gagcattgtg gatacatcgg tatgtgatat
     9541 taaaaatgcg ggtctcttcg gacttatctc ctccaaaatg gattacgcta aaaagaccgg
     9601 aattaaattc aacctgcagg caataggtga aatagactcc attcccaatg ttaagatctc
     9661 cgaactttgt gaaataatag ggatttatct ggataatgcc atagaagccg ctgcaataag
     9721 tggtgataag gaagttgaaa tgcgtctgga aaataaagaa gaaagtattg atattgtaat
     9781 agataacagc tgcagtatca ttccaaatct tgaaagtatc agacaggacg gttattctac
     9841 aaaaggcacc aatcgcggac acggtttgag tatagtcgac aaaattctaa gcaagtatgc
     9901 cagtatctcg aataccatta attttgataa taaaagtatg atctttaccc aaatactgaa
     9961 aataaaaaaa ggcatatagc ctttttttat ttcctttagt ctatttcagt aatgatttgg
    10021 ggcactcctg ctgataaaac gaagagaacc aacaagcccc tgccgaagaa gttgccgcga
    10081 taattccaac catggacaaa acagtcatta ccatcaacct gattttacct tttttcattt
    10141 aataccccac cctttctatt ctttgttatt ttatacacca ccggtgtaag atttacggca
    10201 ttgatcaatg taataattga cataacattc gaaaaatcct ttggcacaaa aaagctgatt
    10261 acaaaacata tgataaaaac tacactgctc ttgattctta attccttccg tctcttttcg
    10321 gtaattatcg gcttcgaaat taaatcagcc ggagcatata agtacactag aacacctgat
    10381 atgataaaca aaataatatt taaataatta aaagcgataa tatgcgacaa ataaatggtt
    10441 ccaaatataa atgtaaaatg tgtaataatg caacccagct gagttttagc atgaataccg
    10501 ccgaaataag acttgtttac agagaatacg gcaacggcta ccaatgcata ccttaactgc
    10561 ccgagggcga atgccgtcag taataccgct attagcttga gaccgtcgga aaaggccata
    10621 taaagaccat aatctatttc ttccgctttt tcttccgtga tacccggtac tgtaataagt
    10681 atctcatttg taattttttt agtgatctta ctcaacatat aatcaccacc tattacaatt
    10741 tactccatta tatactattt tttataacta atctatatat ttcttaaaaa ttcccttttt
    10801 gttaagaaaa atttacaatt tttttataat ataacttcca aaaactaaaa aaacaagtaa
    10861 agtgccgtaa ttttttacgg cactttactt gtttttcttc ctgccagctg atattacaat
    10921 aatattacag cggctatggc agcagcagcc agtgcataat gccaccacct gatcaaggaa
    10981 ttttctaaag gagcctcaac attcttcagt ttttccaaat aaaaccttgt catacgctca
    11041 tctcctttcc ttgtcttggc tctccaccat ttaacgggtt tgtgtattta tattccatat
    11101 atacttataa ttcccttctg ctttttataa atatattttt atcttgtcat gatttatgga
    11161 tttttattta tataaaattt tgatcccaat atttgtatat gggattggct caacagagta
    11221 ccagctcccg gctatagctt tttactcttt ttaatggcat aaaacaacgc cagccataat
    11281 ataatggttg acgttatccg gaagcattta ttatttctaa aaggtccata attttcttga
    11341 taaaatcaca tgattaaaag tataaataca taaacaactg tgttatcaag gttttagtat
    11401 aactttaatg caatggtctt cctttttatc aaaaatctta tacccatgct cacccatatc
    11461 cagggatagt ttatgagtta taatgtcagt agcatcaaac ttaccttctc cgatcagctt
    11521 taatatccgg tctacatagg tatgcgcagg gcattgaccc atctttaatg tgatatttct
    11581 tgagaaaaag tccccaagag gaaacatatt gtacctggcg ccatagacgc caaccattga
    11641 aacggttccg cctttacgta cggcctgagt agccagctca atagcagatt tggagccgcc
    11701 ttgcagtttc attgcagttt caattatttc aaaagttgtc atcttcccat ccataccaac
    11761 acaatcaata accacatccg ccccgccatg agtgatttcc ttaatatatt cccctgtatt
    11821 ttcatgctct tcaaaattaa taacttctgc accatatttt gcagcatgct gtaatctata
    11881 atcaatatag tctactgcaa ttaccctgtc tgcaccatga aaaaatgccc attttactga
    11941 taataaaccc acaggaccgc agcctaatac aactacggta tcaccttttt ttacaccacc
    12001 attttcaacc ccccaatagg atgttgggag tatgtctgtg agaaataata cctgctcatc
    12061 cgtgagatca tccggtacct gcaccgggcc tacatttgcg taaggaaccc tgagatactc
    12121 tgcctgccct ccatcatatc ccccataggt tttgctgtat ccaaatatgg ctcctgtttc
    12181 tccatttgca tttgagttat cacactgact ccataaatca tgctcgcagt accagcagtg
    12241 tccgcatgaa atgggaaaag gaacgatgat gcggtcccct ttttttactt tatgaacacc
    12301 tttgcctgct tccactacaa tacccatcgt ttcatgccct aatacaaagc caaaaggcat
    12361 atttggtacc ataccatgta ttaaatgtaa atccgaaccg caaatagccg tagatgtcac
    12421 tttaactata atatcatcat cattcctgat ttgaggatca ccaatatttt taacttttac
    12481 atttttaatt ccttcatata cgatagcttt cattttcatt cctccgtata aactattaaa
    12541 attaggcttc cctttagatg tataaatatt cttgcggata tttttctgaa agctgcaaaa
    12601 cctaaatatg atattaatta ctttttatta ataaaaggag ttgttaaaaa tgtttaaaca
    12661 tgataaagca cttcttcatg aagtcaaggt agatggacct aatccggctt atgctgccat
    12721 gatgcaggaa cagctgggag gccctcacgg ggaattaaaa gccgcactgc aatatctttc
    12781 tcaaagtttt cgtatcaaag atcctcaaat aaaagatctg ttcctggaca ttgcctcgga
    12841 ggaacttagc catatggaaa tggtggccac aactataaat ctcttgaacg gtcatgtact
    12901 tgatgctaaa aatgcaacaa taggaaatat tcaggcacat gtttcaactg gtcttactcc
    12961 ggcattgaca agtgcctcag gacaatattg gacagccgca tatattgaag aaaccggcga
    13021 cctggcagct gatatcctgt caaacatttc tgcggagcag cgtgccaagg ttgtttatga
    13081 atacctctat aggcaaatac ccgataaggg tgtaagacaa actattgatt tccttttaaa
    13141 ccgtgaggaa gcccataata caatgtttag agaagccttc aacagaattc agtataccgg
    13201 ttcattgagg gactggggca tcacacagga ctccaagtta tacttcaatc tctcaacacc
    13261 aggagatcaa ttttttaatg ccaataaccc gaatcctgca agttttaatg cacctaacgg
    13321 aggcagtccg gctaactgaa aaatttaatc aaatagttaa tttattccat gcctatggaa
    13381 acaacactta agaaaaaagt aaaaaaatag ctctcaagga tttctgcgat gctccctgag
    13441 ggctttttat caataattag gatctcactg ttgacttgaa ttattttaat caattttaag
    13501 aattaaccca ttgatatcca ctctattttc aatcatgcca ttgtctttca tgaactgttc
    13561 tgtctttttc atagaagtga tatcagcctc agtgatttca gtactgaaat catacatcgg
    13621 gaacatttcc tttaccgctt ccatactcag ctcggtttcc ctggcagtga tttcgagagt
    13681 ttcctcagcg ttttccttca tgtactgagc tatctctgac tgcgcttcca ggaaccgttt
    13741 gaccagtaaa ggattctttt catagaatgc tccgcttgtg gctactacaa ttgtagcgtc
    13801 caccaggtct tttcctgtgg tcaccacacg gtagccgtcc ttagccatat tatatgcaac
    13861 cgggcctgca aactttctgc ctttgagatc agcagctgtt tgaatagtgc tgtccttgcc
    13921 ggcgaacaag cgaaatgcct cgggggatgg ccatatgtac tgataatttt aatatccgca
    13981 ccgttggagg ccgacagtat gaccgaagta gctcccaccg cgtataagaa ctgaatatcg
    14041 ccggaagcta atgcctgggt ttgctcaggt cccgtagtca ggtttgaata ttccaccggc
    14101 aagccatatt ctgaaaaggc tttcgtgaag atacccttct cttagctgca tttcggccac
    14161 ccggtagctt ttgcacaaat tttccaacct aactccagct attgtcaaca cctccatggg
    14221 ccagaagtgt tagacttcca ctatgtttcg ttaatgagtg tattcaaaac ttcttgcaca
    14281 tgaggtgagg cttttattgt tcctcgtact ttaacacttt ctatggtttc tttcgccaaa
    14341 tcaggtgtaa catcttccga aaatgccagt atgccagtca ttttaatgtt tgcctttttg
    14401 ttggatgtct ttaattcttc taaatcccta cgagtaatag taacgatacc aagtgtagca
    14461 gaacttggtt tgccgataat attctcgtta aactctgcta aaagatcatc cagtccaatg
    14521 tcgtttcttt tcattgcaaa aatcctccta aaaatattta tttcatacat attgtatgta
    14581 tatatttagc taaaagaatt acttttttgt aattctcttc tgcttgtctc attttttgat
    14641 ttcaacaacg ataccttgat catttattac aacatgagaa gtcagggttt tatcgagaac
    14701 cggcaacccc aaaaaatcaa caatatcctt tgccatatta aatctttgcc acgcttcttc
    14761 ttcgtttgac tgcgggtata ttgtcggcat catccaaaca ttacaaatca gcaaaaacaa
    14821 ttccgctgtt aatttcggat actttgcttt gattgagcca tcgtttatac cttcttcaat
    14881 aagttcagca tattttgatg ctaaaaaggt tcgctgtttt tccatatata tcttaaaagc
    14941 tatcgggctg ctttcaatca atggaagtat ttgaaggtga agtacggcat attctttgct
    15001 ctcgtttaat atttgcaaag tcagttttat tttttctaaa ccatttatgt cggtacggac
    15061 tttgattttt gtaaaagggt ctatatcatt aaataattta tcagtcagcg caaaaaaaac
    15121 ttcttccttt gttttgaaat ggtgataaaa ggctcctcgc gtcaggccac ccatttcatc
    15181 gactatatca agaattgttg tttgctcata gccattttca ataaacagtt ttaatgcagc
    15241 gtcaagtatt atctgctctg tttcttcggg atatttgttt cgtggcataa atgcacctct
    15301 tttcatacac tgtgtatgtt taaaatatag cagagggaaa atgctttgtc aacaaataga
    15361 tacatcttgt atctatgatt aaagcgacaa gaaaaaagag tgcgatggca ttaaacctac
    15421 cgcactccct taatacttag ttataaacta gctctgcaaa tatgatttcc tccacccatg
    15481 atttggctgt atttatcaag cctacccatt tcatttggtc ggtagctttt agttgctctg
    15541 tatggtgttg tccatggtgt caaagttctc gtatttttca ataagtgcaa tgaatttact
    15601 ggctgatttt tggctctgct caaagccgcc gatagtcttt tcaagctctg cagctcttct
    15661 ttctggcaat ggcaagccgt ttcttttgct tggtgacatt ggtggtctgc cgtgcgttct
    15721 gtgcctcctg caccgtccgt ataaactcgg ctctgtcgct cttggaatac tccgcaatcg
    15781 ttttgagcat atcggcagcc aaaaccataa ccacctcggc attgacggtg ctgcgtggtg
    15841 cagagctttc caactggcac tttgccgtat tgagagcaaa tatattgcgg tttgcgtttg
    15901 ccgttgtagc tgcgatgaac atacatttta ccgccacaat cggcacaatc atcagttctg
    15961 ttaatggcgg caattcacca aagccactgg gatagcggct tttcttatcc ttgaaatgca
    16021 tgcgtgtctt gaacttaacc gtataccctt ttttattcat gccctcgcca tatcgggcaa
    16081 ggtggacagc aggaatttca atcttttgct gtgtgagtag ttggaaaatc tgatacgttc
    16141 cgaaaaccac cattgttagg ctgaaaatct atcgtacagt ggcggcggca tcatcgtcaa
    16201 taacctaatg cccacgcttt tcatctccca aaggtagcca tacggcacct gtcctgtcat
    16261 gtgcttgccg ctcatacctt tagctttaaa aataggcttg atttttcggc ttgtatctct
    16321 ggcgtagtat tcgttatagt gtttctcttt gggtaagaaa gaataattca cccgatatat
    16381 ccaacgaatt tgtaatggat acggatttcc cgttgtttct gattgccttt tacttcgcgc
    16441 tccccaattt cattttatct atcaatttca agagaatatc gcggtcaaga ctatattctg
    16501 aatatgtttt gacggtttgt aaactgcaac aatggcagca acaaaaacaa acaaaagaat
    16561 tatcactaaa ggaacaatag gcacgctcca agtcgcataa ctaaaatgag cggtaatgag
    16621 agtgtcatac aagaacttgc taaccagtaa accaactgca caaccgacga cacaaccaga
    16681 taacgcatag gtaaatgctt ccgcagctat cattttagta acttgatgtg tgtccatacc
    16741 aatcgcacgc atggctccgt attggtttat tcttgcagat acgctcatgg aaatactgtt
    16801 cataatattt aagacggtaa ccaaagtgat gattactaaa aacccatata tacatatctg
    16861 gaaagccatg taagtaccgg cggtactttg ttcgcgtctg tcttgaagcg tgcagttttc
    16921 atctaataca ctgctgattg ccgctatatc ctcgtctgtt acggtttttg gtgcctgtat
    16981 cataatgagt gaataaccat tgataccagt caaacggata aaagtttcgc cggaagtaat
    17041 aatcgttatt tgcccgtttg cgctgccgtc actgttgaaa gggtcatatt tcaacagtcc
    17101 tgcaatttca agttctccat ttcctatttg tatcttatcg cctatttcta agggactatt
    17161 cgtgtcgcag attgcaagta cataattact atctccatac acctttgaaa tatcgctgcc
    17221 ttttctaagc agcttatctt tggtaagaca atctaaatca aattcatcaa aggaaatcat
    17281 atcaaccgtg cttgtcagtt gattgtcgtt ccttatttcc gctggaatgt caaataaact
    17341 tctgcgtcca aaaacagatt ttacaccttg catagtgcta atttcagtaa gcattgcact
    17401 atctattgag tttgagccgt cactacttga aatgtcaatg tcagaagcat ttgacgattg
    17461 gggcataaga tagccgataa actgtatcaa aactgaaaaa cttaaaaaaa gtataatact
    17521 aagcgcgaat gagcttatca taagcaccaa atttttcttt cccgatacgg catgatgaac
    17581 gccaagagcc gtttcaattt tagaaaaacg ggtatttgct gcatgggtga ggatttttgc
    17641 gttttctgaa ttgccggata ccgccgttat aggcgatact ttagcggctc gttttgccgg
    17701 ggaacttgcg gcaataataa ccgtcacaat ccctacgaca attccgctga taataccgat
    17761 cagactaata ccgaaaaggg gaatttccga gaactcctca ccgacaagaa accgtaatgc
    17821 tgcacataac ccccatgtga ttgcaattcc aagtacaacg cctatcggaa ccgccgtttt
    17881 gcaccagtta agagcttcca gcctcacaaa acggataatc tgccgtttgc tcattccaat
    17941 acaacgcatc attccaaaaa actttgtcct ttgggcgacg ttgctgttta agctgcttga
    18001 aatcatcagc acacccgcaa ccaatatcag gacaaataat accgcagccg ccagaaatag
    18061 cgtttgtgcc agtgtactgc taagcaagtc ttgaaatgtc agactactac catgcttatc
    18121 caataatctt gtttgttcca ttctaacgcc catatctgcc atgctgaaaa tagctgttac
    18181 caaaaacacg gcaaagatga tacatagcag cgtcatacgg ttttgccgtt tatgcacttt
    18241 tgcagaaatc gggattaggc caagatagct tttcattcgg tatacccccc aaaatcggag
    18301 agtacaccgt ccgaaacctg caatacacgg tcagccgtag acgcgacact gcggctatgt
    18361 gtaatcatta tgatggtttg gctgtaccgt ttggacgctg ttttgagtag tgaaataacc
    18421 tcactgctat tgttgctgtc caaattgccg gttggctcgt ctgcaagtat cagcatagga
    18481 cgggtaatca acgcacggcc tatggctacg cgctgctgct gcccgccaga taattgccgt
    18541 ggcaaatgcc cccgcctgtc ctgcaaggaa agcactgtca atatttcttc gacatacgcc
    18601 ttatccgggt ttttgtaatc gagcagtaca ggaaatgtta tgttttgctc tacattaagc
    18661 tctggaataa gattgaaggc ctgaaagata aagccgatat tcctacgccg gaaaatggtt
    18721 agcttttcgt ctttcatgcg aaatatatcg ttgccgtcaa tccgaacatt gccggacgta
    18781 ggtgtatcca atgcgccaag catattcaat agcgtgcttt taccggaacc ggattcaccg
    18841 acaacagcaa caaattggcc tttgggaacg gaaaaggaaa cgtcctttaa ggctttaacc
    18901 gccgtatcac cattcccata agttttgcat aatgcgttca cttctaataa attcatatgt
    18961 tatccacttt ctttctgcat tgatattgaa aggttattac gtcctactgt tatatgacgc
    19021 ttactctaca attttgtagg aattaaaaaa ttgattgtaa aagtagtacc aatacctaat
    19081 tcgctatatg gtaactgctc atatcaccct gcgtttacta catttactat gctcattttt
    19141 tcaatcttct ttgccggtga aatgaccgcc ataaacgtag tgagtagtgc ggcaaaaatt
    19201 gtgatagcta atactacaag tggcggctgc cagttttcac cccagttgga cgtaaccaaa
    19261 agattaaaaa agaagcggtg cagcagaagc cctaaaacac ttcccgcaat gctgccggtt
    19321 atggcgtagg ctgcggcttc ggcggtaatt atttttttga gttgcttgcc cgacatacct
    19381 accgcccgca taacaccgta gttattcatt ctgctggaaa cactcgcgtt tacggtgttg
    19441 acaatattaa tcagggcaac aaaggcaatg atcatcaaaa acccatagac gaataccgcc
    19501 atagcattgt aggttgcgcg agtttcattg ttactctgga acttatcaag catttgcacg
    19561 tcagtaccaa tcaagctcct tacctgcgcc gaaatatcag aggtggcctg aacatcaata
    19621 attgtatagc cagatactcc gctaagttta gtaaacgtat cctcggagca aatgacaagc
    19681 cactcgccgt tttcagcagt aaatggcgta ctggaaagta cccccgcaat agaaagctct
    19741 gcgtcctctc catttatatt cagagtgatt ttatcgccgg ggttccagtt catatgttcg
    19801 gaatattcaa caaacacacc gtttccgttt tgaacatcat caatgcgccc tgtgatgagg
    19861 gcatctttcg cccattcaaa ttgaggttca tcataagaga taagtgtcga gatgctttcg
    19921 ctttgtttag cacttgccgg aatatcatag aggaacatcc ttgcatagac attttctgtt
    19981 tcaggaagct ccttaatttc ctccagcaag gaaaggtcaa gtggcgtaga agcatctgaa
    20041 cctataaccg aaatatcggg agcatacggc tgcaacggtc taagtgcatt gcacataaaa
    20101 tctatgaaaa cggaaaaaca caagaacata acaatgctga ttgcaaagga accggttatt
    20161 agcatcaggt ttttcttatt ggaaaaagca tgacggaggc ccattgctgt atccacatga
    20221 aacagctttg tattggatgc cttatctatc ccctgattat tggcctggtt gatatttcct
    20281 gtaacagcgg cttgtgggga tacccctgcc gctttttttg cgggagcgcg ggatgccagc
    20341 ataacagtca tcactccgat taccgcaccc gcaagtaacc caagcaagct aaactgaatt
    20401 ggcatttgag gtaaaaaact tgaatttaag gtattgagaa gcacaaccgc cgcccagatc
    20461 acgcagcacc ctgttaaaag gccgataggt acgccaatgg cacaataccg caagccctca
    20521 agccgtatat accgcttaac ctgttttttt gtagctccaa gacagcgcaa caacccaaaa
    20581 aactgtgtgc gctccaaaat actcatgtta aagctgcttg caatcataaa cgtaccggcc
    20641 atagcgacaa gaatagccaa aattacggct gtgagatata attgcaacaa actgctgtcg
    20701 tcactttgcc ccatcagt
//
