LOCUS       NZ_AP024846.1          18166 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_AP024846.1 [Clostridium] scindens strain G10 chromosome, complete
            genome.
ACCESSION   NZ_AP024846
VERSION     NZ_AP024846.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:40:48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 702210
            Orig. end    :: 720376
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..792
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_699"
                     /sec_met_domain="PF00881 (E-value: 6.4e-23, bitscore: 79.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRIEKERCIGCGACIKDCPASAIRMTEEKAEAYKDCLLCGHCVA
                     ICPSEAVSIPEYDMEDVEAYDKDTFTLKAEYYLHAVKFRRSIRNFKPEKIEREKAERIL
                     KAGRYTATAKNRQACTYVFIQEQLDEFKELVWKEMPSILEELKQNAPDYARAFELFYLK
                     WKRNPKDDTFFFNTPAFLVIASNNPLDGGLAAANIENMAVAEGLGALYSGYMMRVIGLS
                     QTLREWLGIGEKRVSCCMLLGYPAVSYRRTAPRKYADILWK"
     protocluster    1..18166
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[710892:711258](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8683..9048
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..18166
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18166
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     PFAM_domain     4..144
                     /aSDomain="Fer4_10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13237.8"
                     /description="4Fe-4S dicluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_699_0001"
                     /evalue="2.20E-09"
                     /label="ctg1_699"
                     /locus_tag="ctg1_699"
                     /protein_end="48"
                     /protein_start="1"
                     /score="37.3"
                     /tool="antismash"
                     /translation="IRIEKERCIGCGACIKDCPASAIRMTEEKAEAYKDCLLCGHCVAI
                     CP"
     PFAM_domain     244..732
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_699_0002"
                     /evalue="1.30E-19"
                     /label="ctg1_699"
                     /locus_tag="ctg1_699"
                     /protein_end="244"
                     /protein_start="81"
                     /score="71.0"
                     /tool="antismash"
                     /translation="KFRRSIRNFKPEKIEREKAERILKAGRYTATAKNRQACTYVFIQE
                     QLDEFKELVWKEMPSILEELKQNAPDYARAFELFYLKWKRNPKDDTFFFNTPAFLVIAS
                     NNPLDGGLAAANIENMAVAEGLGALYSGYMMRVIGLSQTLREWLGIGEKRVSCCMLLGY
                     "
     CDS             complement(821..1948)
                     /locus_tag="ctg1_700"
                     /transl_table=11
                     /translation="MKVVVAMDSLKGSLTSMEAGIAVEEGILAAKPDAKVIVKPLADGG
                     EGTTDALIEGMKGERVDLTITGPMGTKVHAYYGYLEETKTAIIEMASAAGITLVPTDRQ
                     DPLSATTYGVGEMINDAITKGCRNFIIGIGGSATNDGGIGMLKALGFVFLDSQGNDVGE
                     GAQALSKVAAINSAKKNPRLAECTFQVACDVTNPLCGKSGATYIYGPQKGVTEEQKDAL
                     DQAMTHYAQITADTFGCSYAETEGAGAAGGLGFAFLSFLNARLTPGIDLILDAVGLEEE
                     LRDADVAVTGEGRLDHQTAMGKAPVGVTRLAKKYNVKVLAFAGSVTKDAASCNQAGIDA
                     FFPIVRGVTTLEEAMKPERARENMRASVEQAFRLL"
     PFAM_domain     complement(824..1942)
                     /aSDomain="Gly_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02595.17"
                     /description="Glycerate kinase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_700_0003"
                     /evalue="1.90E-143"
                     /label="ctg1_700"
                     /locus_tag="ctg1_700"
                     /protein_end="375"
                     /protein_start="2"
                     /score="477.9"
                     /tool="antismash"
                     /translation="VVVAMDSLKGSLTSMEAGIAVEEGILAAKPDAKVIVKPLADGGEG
                     TTDALIEGMKGERVDLTITGPMGTKVHAYYGYLEETKTAIIEMASAAGITLVPTDRQDP
                     LSATTYGVGEMINDAITKGCRNFIIGIGGSATNDGGIGMLKALGFVFLDSQGNDVGEGA
                     QALSKVAAINSAKKNPRLAECTFQVACDVTNPLCGKSGATYIYGPQKGVTEEQKDALDQ
                     AMTHYAQITADTFGCSYAETEGAGAAGGLGFAFLSFLNARLTPGIDLILDAVGLEEELR
                     DADVAVTGEGRLDHQTAMGKAPVGVTRLAKKYNVKVLAFAGSVTKDAASCNQAGIDAFF
                     PIVRGVTTLEEAMKPERARENMRASVEQAFRLL"
     aSDomain        complement(827..1945)
                     /aSDomain="TIGR00045"
                     /aSTool="tigrfam"
                     /description="TIGR00045: glycerate kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_700_0001"
                     /evalue="1.40E-139"
                     /identifier="TIGR00045"
                     /label="ctg1_700"
                     /locus_tag="ctg1_700"
                     /protein_end="374"
                     /protein_start="1"
                     /score="463.3"
                     /tool="antismash"
                     /translation="KVVVAMDSLKGSLTSMEAGIAVEEGILAAKPDAKVIVKPLADGGE
                     GTTDALIEGMKGERVDLTITGPMGTKVHAYYGYLEETKTAIIEMASAAGITLVPTDRQD
                     PLSATTYGVGEMINDAITKGCRNFIIGIGGSATNDGGIGMLKALGFVFLDSQGNDVGEG
                     AQALSKVAAINSAKKNPRLAECTFQVACDVTNPLCGKSGATYIYGPQKGVTEEQKDALD
                     QAMTHYAQITADTFGCSYAETEGAGAAGGLGFAFLSFLNARLTPGIDLILDAVGLEEEL
                     RDADVAVTGEGRLDHQTAMGKAPVGVTRLAKKYNVKVLAFAGSVTKDAASCNQAGIDAF
                     FPIVRGVTTLEEAMKPERARENMRASVEQAFRL"
     CDS             2420..3622
                     /gene_functions="other (smcogs) SMCOG1237:transposase
                     (Score: 218; E-value: 3.9e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg1_701"
                     /transl_table=11
                     /translation="MISVGIDVSKGKSTVCILKPYGEIMCSPFEMLHGEKELNALDDLL
                     NKLDGEIRIVMEATGIYHLPILTFFHEKGYFVSVINPFAMKKYAKDNSIRGAKTDKLDS
                     IMIANYGIEKWFKLQRYKGDEEIYAELKLLGRRYRHYMELHVKALQELTHILDYVMPGI
                     KKMFNSWNEANGKDKLSDFVEQFWHFDLITAMSLEKFTEEYLDWAKEKKYHRSRSKAEA
                     VYELASNGISTLSSGTPSTKMLVQEAISVLRTVDSSLFLILTRMQELAKTLPEYSTVRE
                     MGGVGDVLAVKLIAEIGDIRRLHSAKALIAWAGIDPPPYESGQFIGSKRKITKRGSSTL
                     RKVGYEVMRVLKSHPAPKDDAVYNYILKKESEGKSKKHAKIAGLNKFLRIYYARVMAVY
                     Q"
     PFAM_domain     2429..2902
                     /aSDomain="DEDD_Tnp_IS110"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01548.19"
                     /description="Transposase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_701_0004"
                     /evalue="4.50E-35"
                     /label="ctg1_701"
                     /locus_tag="ctg1_701"
                     /protein_end="161"
                     /protein_start="3"
                     /score="120.9"
                     /tool="antismash"
                     /translation="VGIDVSKGKSTVCILKPYGEIMCSPFEMLHGEKELNALDDLLNKL
                     DGEIRIVMEATGIYHLPILTFFHEKGYFVSVINPFAMKKYAKDNSIRGAKTDKLDSIMI
                     ANYGIEKWFKLQRYKGDEEIYAELKLLGRRYRHYMELHVKALQELTHILDYVMP"
     PFAM_domain     3251..3508
                     /aSDomain="Transposase_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02371.18"
                     /description="Transposase IS116/IS110/IS902 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_701_0005"
                     /evalue="1.30E-19"
                     /label="ctg1_701"
                     /locus_tag="ctg1_701"
                     /protein_end="363"
                     /protein_start="277"
                     /score="70.3"
                     /tool="antismash"
                     /translation="TVREMGGVGDVLAVKLIAEIGDIRRLHSAKALIAWAGIDPPPYES
                     GQFIGSKRKITKRGSSTLRKVGYEVMRVLKSHPAPKDDAVY"
     PFAM_domain     4326..4511
                     /aSDomain="PhdYeFM_antitox"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02604.21"
                     /description="Antitoxin Phd_YefM, type II toxin-antitoxin
                     system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_702_0006"
                     /evalue="2.30E-09"
                     /label="ctg1_702"
                     /locus_tag="ctg1_702"
                     /protein_end="62"
                     /protein_start="0"
                     /score="37.0"
                     /tool="antismash"
                     /translation="MNIRPSAAIRQNYNEIADMCRKTAEPIFLTKNGEGDLVVMDIETY
                     NRREKMLKLREELLAVE"
     CDS             4326..4613
                     /locus_tag="ctg1_702"
                     /transl_table=11
                     /translation="MNIRPSAAIRQNYNEIADMCRKTAEPIFLTKNGEGDLVVMDIETY
                     NRREKMLKLREELLAVEEDRMHGSTGYSVGEVAAMMRSAIKEAAGHGKTE"
     aSDomain        4347..4490
                     /aSDomain="TIGR01552"
                     /aSTool="tigrfam"
                     /description="phd_fam: prevent-host-death family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_702_0002"
                     /evalue="8.60E-06"
                     /identifier="TIGR01552"
                     /label="ctg1_702"
                     /locus_tag="ctg1_702"
                     /protein_end="55"
                     /protein_start="7"
                     /score="23.0"
                     /tool="antismash"
                     /translation="AIRQNYNEIADMCRKTAEPIFLTKNGEGDLVVMDIETYNRREKML
                     KLR"
     CDS             4597..4914
                     /locus_tag="ctg1_703"
                     /transl_table=11
                     /translation="MEKQNRYRVIVSERATQMLVSHAAFLAQVSPEEAERLTAEFEKTA
                     NSLETMPQRCPWLTGEYIPRNAYRFILFEKRYMIIFQIVDDIVYADYVVDCRQDYSWLI
                     R"
     PFAM_domain     4621..4896
                     /aSDomain="ParE_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05016.17"
                     /description="ParE toxin of type II toxin-antitoxin system,
                     parDE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_703_0007"
                     /evalue="1.20E-07"
                     /label="ctg1_703"
                     /locus_tag="ctg1_703"
                     /protein_end="100"
                     /protein_start="8"
                     /score="32.4"
                     /tool="antismash"
                     /translation="VIVSERATQMLVSHAAFLAQVSPEEAERLTAEFEKTANSLETMPQ
                     RCPWLTGEYIPRNAYRFILFEKRYMIIFQIVDDIVYADYVVDCRQDY"
     CDS             5443..5805
                     /locus_tag="ctg1_704"
                     /transl_table=11
                     /translation="MRKKVFRILCIIFSAGVFMSVFYPWTVLNGESYTIIEFYKQAVFD
                     KQLYTMADMGGSVYLLLIFLIFPMVVGILSGVKAVLLVFRKNYYLLGEIINISELISVA
                     AFFAFQGYELLTAPFF"
     CDS             5845..7986
                     /locus_tag="ctg1_705"
                     /transl_table=11
                     /translation="LSDVDRFTNEWEIHKIKNRTEKEERKQRLAFPGNYDRRLRKIIRK
                     DALHPSKAVVLVCIGNGILLGSAFALFAVKEQFQKNYSAKAVLPTEGLNGILTNGLLVI
                     TIFYIFFAIAAFFNYVHNHQERRNLFWTLGSRERLNSIAWKMEYEFMIVLSMIPGYIIG
                     VGIYNLLRVMLKKELGVLIDGRTQLQLYFLSGLLYLCLSGVIIWLSSILLRKELRGEKR
                     NIRKLSTPTKGVAVITVMLSLGYLVFSIGRYMQRRNGESLNIFVYGIILGGICVLCSIR
                     LLESLNRRGKAQNFQVLLDKIPMQSGFFKEAGLQSVVFAFHFIFLGFLSVTMAGKLSAP
                     SPDTLFPHEYVCMAYPEDEELFTELRDKNLADVKSYPMIRVTSVQGNPTDWIDIANNYY
                     RKIIWPQGQHIGISRSTYESLCTDEKKNISNFTLSEDEIYVVYQEDCSVKAHPLEWYMN
                     RRTPFIKEGQPLRWYNPFARENYYPPRKVIGQERKVLTGVFERGIQEHIVVFSDDYFNQ
                     LHDVDGPSVLYFVDCLEKNKKEVEKVLSVFASRHMEDSSWDRLIQPYYSKTEKITDMEA
                     ERKLEQISTSIEMLLSVFCVFIFCFIKIEFEQEEKQKRFQTLFCLGMHKKQVKHSLWRE
                     ICLFIWLPLIFAYTLATVVVTFIWKMRFVTGAESRKLWMTLIIIWTIYLLLQMLLTFVL
                     YRYQLNNLNLKNGVRGRRR"
     CDS             7983..8660
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 188.6; E-value:
                     2.2e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_706"
                     /transl_table=11
                     /translation="MKIELKDIKKSYQIPGQDEFKVLKGINFLISQGEYISIIGRSGCG
                     KTTLLKIVGLLDIPTEGDVIIDGVKEKELWNDELADLRRRKFGFIFQDYFLLEHLTVLD
                     NMILPALLDKAEEKKSLERAEELANYLQIDNRLLLKYPKELSGGEKQRVAIARALFNDP
                     DILLADEPSGNLDEQSKKNVEKIFKDLHENINKSILLVTHDLEFAKWSEKCYQLQNGVL
                     VKG"
     PFAM_domain     8049..8498
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_706_0008"
                     /evalue="2.40E-32"
                     /label="ctg1_706"
                     /locus_tag="ctg1_706"
                     /protein_end="172"
                     /protein_start="22"
                     /score="112.4"
                     /tool="antismash"
                     /translation="LKGINFLISQGEYISIIGRSGCGKTTLLKIVGLLDIPTEGDVIID
                     GVKEKELWNDELADLRRRKFGFIFQDYFLLEHLTVLDNMILPALLDKAEEKKSLERAEE
                     LANYLQIDNRLLLKYPKELSGGEKQRVAIARALFNDPDILLADEPS"
     CDS             8683..9048
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_707"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.2e-18, bitscore: 62.7, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="VIEKPFIHLFKTTKGQYCYDVNKDEIIQLPDDVYMYLAGKGEKTD
                     YVKTYIEQLYERGYLKSKRVITTKHPATDYLSYYYDTKLNFLILQVTQNCNLRCEYCVY
                     SGNYRTRSHNNKRMSLI"
     CDS             9580..9843
                     /locus_tag="ctg1_708"
                     /transl_table=11
                     /translation="MKYFNAKLILPDALVKELQNYVQGGYIYVPIEQEQQKRWGEVSGY
                     RQELEQRNEQIKREYQNGISMECLSEKYGLSFYAVGKIIYQK"
     CDS             10009..10215
                     /locus_tag="ctg1_709"
                     /transl_table=11
                     /translation="MITGFNFDIDLSVWKHKVIEEKERVFCKHFLEKNAKYFWRMLHLQ
                     IGESCKASAGSYSASYIAIADHI"
     CDS             complement(10219..10461)
                     /locus_tag="ctg1_710"
                     /transl_table=11
                     /translation="MAKNKKVIKEQKKYQNLQERYEEMNDYLLDLIEDHRCAEEDLRYL
                     NDFIHYKELDEEFRYFREHAHEDENSELPFPYLTL"
     CDS             complement(10454..11227)
                     /gene_functions="other (smcogs) SMCOG1151:transposase
                     (Score: 238.1; E-value: 1.2e-72)"
                     /gene_kind="other"
                     /locus_tag="ctg1_711"
                     /transl_table=11
                     /translation="MADIEKSIAACCKQLKLSTNFAGQAFEQKGDTPQEYLLNLLTNEI
                     EYRTAKRKSKFLNTAGFPRRYRVEEFRADEIDFPEDVSFQSLLDLEFYHTGKNVIMYGG
                     TGTGKTMLSILIGMSACNQEIPVRFYRTAGLINLFSESQSSGKLTALKKKLNSARILIL
                     DEFGYVPYDRTGSQLLFDYLSEIHEQKSVILNTNLEFSQWVNVLYDQRMTTALIGRLTH
                     HVELILFPGINNRLRESSINATLSRISSQEAGNNG"
     PFAM_domain     complement(10508..11131)
                     /aSDomain="IstB_IS21"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01695.19"
                     /description="IstB-like ATP binding protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_711_0009"
                     /evalue="7.50E-45"
                     /label="ctg1_711"
                     /locus_tag="ctg1_711"
                     /protein_end="240"
                     /protein_start="32"
                     /score="153.4"
                     /tool="antismash"
                     /translation="PQEYLLNLLTNEIEYRTAKRKSKFLNTAGFPRRYRVEEFRADEID
                     FPEDVSFQSLLDLEFYHTGKNVIMYGGTGTGKTMLSILIGMSACNQEIPVRFYRTAGLI
                     NLFSESQSSGKLTALKKKLNSARILILDEFGYVPYDRTGSQLLFDYLSEIHEQKSVILN
                     TNLEFSQWVNVLYDQRMTTALIGRLTHHVELILFPGINNRLRESS"
     CDS             complement(11220..12764)
                     /gene_functions="other (smcogs) SMCOG1213:transposase
                     (Score: 443.5; E-value: 8.9e-135)"
                     /gene_kind="other"
                     /locus_tag="ctg1_712"
                     /transl_table=11
                     /translation="MSTTMDQIHHIRDMFYRQDKNISEIASETGLNWKTVKKYVDMEDF
                     NNPSPKPASSEVHESKLDPFKPLIDEWLQADKLAPRKQRHTAKRVFKRLKDEADGFGCS
                     YRLVALYVKQKKEELRLKRTDGYIPLNHHPGEAQSDFGTADFYENDRLHHEAKYLVLSF
                     PYSNGGFLQLNYGENMECLLEGLVAIFEHIGGVPTEIWFDNTRTIVTEIIKGGGRNVTE
                     RFQRFCEHYRIKPVFMNPESGWEKGNVENKVGYLRRNELVPVPRFDDLVKENKHLLDRC
                     EIDMQREHYDDDDDRFISKLFEEDKARLLPLPSVPFDTALYTTATTDKYGKFTLDAGKH
                     RYSASPAFCESIVNLKITSSDVIVMDKDMHEVVRHKRLYGNEHERMDWLPYLTYIARKP
                     RSLRNSGIYDMMPQTMQIYMDKCESKERGRVLKVLAELTERTGFASAVRTVDEAVRLNA
                     TDPDSLQSLYRRTYADVPLLPPLENKVLLPQQKVIPFRNDLKMLDAALKKGGVSNG"
     CDS             complement(13204..14397)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 156.1; E-value: 2.8e-47)"
                     /gene_kind="other"
                     /locus_tag="ctg1_713"
                     /transl_table=11
                     /translation="MSSAKRRDNKNRILNRGESQRKDGRYTYKYVDAQGETKYVYAWKL
                     LPTDKTPAGKREDLSLREKERIIQRDLFDGIDTKGSKMTLCQLYAKKNAQRPNVKKSTQ
                     QGRKYLMEALKQDKLGARSIDSIKPSDAKEWAVRMKENGFSYKTIHNYKRSLKASFHMA
                     IEDDCVRKNPFDFQLSEVIEDDSKPKVALSEEQEARLLDFMKHDNVYSKYHDDVLILLK
                     TGLRISELCGLTRSDIDFKNHAIRITHQLLKDKDGFYIAEPKTKSGIRNVPMSEETEKA
                     FQRVLNRRQKPKIKEIDGYRNFLFLSPNGYPMQEGSYKFMLNGIVRKYNKNHEKTPLPR
                     ITPHSLRHTFCTQLAQKNMNPKNLQYIMGHASITITLDLYAHASEAGANREMRSLIA"
     PFAM_domain     complement(13246..13824)
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_713_0011"
                     /evalue="6.70E-39"
                     /label="ctg1_713"
                     /locus_tag="ctg1_713"
                     /protein_end="384"
                     /protein_start="191"
                     /score="133.5"
                     /tool="antismash"
                     /translation="LSEEQEARLLDFMKHDNVYSKYHDDVLILLKTGLRISELCGLTRS
                     DIDFKNHAIRITHQLLKDKDGFYIAEPKTKSGIRNVPMSEETEKAFQRVLNRRQKPKIK
                     EIDGYRNFLFLSPNGYPMQEGSYKFMLNGIVRKYNKNHEKTPLPRITPHSLRHTFCTQL
                     AQKNMNPKNLQYIMGHASITITLDLYAHAS"
     PFAM_domain     complement(14182..14391)
                     /aSDomain="Integrase_DNA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02920.17"
                     /description="DNA binding domain of tn916 integrase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_713_0010"
                     /evalue="2.00E-23"
                     /label="ctg1_713"
                     /locus_tag="ctg1_713"
                     /protein_end="72"
                     /protein_start="2"
                     /score="82.0"
                     /tool="antismash"
                     /translation="SAKRRDNKNRILNRGESQRKDGRYTYKYVDAQGETKYVYAWKLLP
                     TDKTPAGKREDLSLREKERIIQRDL"
     CDS             complement(14480..14680)
                     /locus_tag="ctg1_714"
                     /transl_table=11
                     /translation="MHDLSMPLWERYLMTIEEASSYFRIGENKLRQLANEYKEECVVMN
                     GNRMLIKKKKFEKVIDRLEQI"
     PFAM_domain     complement(14495..14668)
                     /aSDomain="Tn916-Xis"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09035.12"
                     /description="Excisionase from transposon Tn916"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_714_0012"
                     /evalue="1.90E-12"
                     /label="ctg1_714"
                     /locus_tag="ctg1_714"
                     /protein_end="62"
                     /protein_start="4"
                     /score="47.3"
                     /tool="antismash"
                     /translation="SMPLWERYLMTIEEASSYFRIGENKLRQLANEYKEECVVMNGNRM
                     LIKKKKFEKVIDR"
     CDS             complement(15523..16653)
                     /locus_tag="ctg1_715"
                     /transl_table=11
                     /translation="MNDMEFIEVLKVKRNACGYSQSRLAKELHISRQNLNEIENGKTRA
                     SKEMKHTLLHYLDYCNCTQPFTLTVDYLRVRFPTTDALEIIKNVLAMKAEYFIHEDYGL
                     FGYEELYRYGEIIVTASKDASMGVLLELKGMGCRHLEHVLQARKTGWYHFLSRCMDYEG
                     IFKRLDLAINDMGGLLDIEILRERYYANKVWKRSRKYEGVDSGKLSGTKGDTAKTFYIG
                     SKNSPIYFCLYEKEKEQRNKGIQTDIKNRLEIRLKNEKAGQAVEELVFSRNPEQTVTSL
                     ILMQMDFPDYILWDIFIENMTASLPFIMTPVAVNMDKTIRWLERQVMPSLLMIKEIEKE
                     TGANYLETIDRQTRLTEKQELKIKQMTTDISDVIIG"
     PFAM_domain     complement(15607..16164)
                     /aSDomain="Rep_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02486.21"
                     /description="Replication initiation factor"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_715_0015"
                     /evalue="7.10E-43"
                     /label="ctg1_715"
                     /locus_tag="ctg1_715"
                     /protein_end="349"
                     /protein_start="163"
                     /score="146.7"
                     /tool="antismash"
                     /translation="IFKRLDLAINDMGGLLDIEILRERYYANKVWKRSRKYEGVDSGKL
                     SGTKGDTAKTFYIGSKNSPIYFCLYEKEKEQRNKGIQTDIKNRLEIRLKNEKAGQAVEE
                     LVFSRNPEQTVTSLILMQMDFPDYILWDIFIENMTASLPFIMTPVAVNMDKTIRWLERQ
                     VMPSLLMIKEIEKETGANYLETI"
     PFAM_domain     complement(16183..16452)
                     /aSDomain="Rol_Rep_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18106.3"
                     /description="Rolling Circle replication initiation protein
                     N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_715_0014"
                     /evalue="7.80E-28"
                     /label="ctg1_715"
                     /locus_tag="ctg1_715"
                     /protein_end="157"
                     /protein_start="67"
                     /score="96.6"
                     /tool="antismash"
                     /translation="LTVDYLRVRFPTTDALEIIKNVLAMKAEYFIHEDYGLFGYEELYR
                     YGEIIVTASKDASMGVLLELKGMGCRHLEHVLQARKTGWYHFLSR"
     PFAM_domain     complement(16507..16626)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_715_0013"
                     /evalue="2.60E-08"
                     /label="ctg1_715"
                     /locus_tag="ctg1_715"
                     /protein_end="49"
                     /protein_start="9"
                     /score="33.9"
                     /tool="antismash"
                     /translation="LKVKRNACGYSQSRLAKELHISRQNLNEIENGKTRASKEM"
     CDS             complement(17037..17198)
                     /locus_tag="ctg1_716"
                     /transl_table=11
                     /translation="MKIFFNIMTIVLLAVLIICAIFYWTTGEYYSISGVALILFIIVVA
                     ARQKYKKE"
     CDS             17654..18166
                     /locus_tag="ctg1_717"
                     /transl_table=11
                     /translation="MTQKTLMDELIKLAKEIKRNIIKKYLKEKTGKKIFVDTIEKYKSG
                     IVYWLPTSHFYVDKDIESILQTLELYYIVSKFNEGSSRKPGVKVSYYGLNYGLCLENTI
                     DYGKPELRRTYDYWRQNEFDYSDFIPAVINKIEVPICRKCGYRYTDKSEYKVAKKFGYC
                     LQPGFSD"
ORIGIN
        1 atgatcagaa tagaaaaaga aagatgtatt ggctgcggcg catgtataaa ggactgccct
       61 gcatcggcaa tcaggatgac ggaagaaaag gcggaggcgt ataaagactg cctgctctgc
      121 ggtcactgcg tcgccatatg cccgtcggag gcagtctcta tcccggagta cgatatggaa
      181 gatgtagaag catatgacaa agacacattt acgctgaaag cggaatatta tcttcatgcg
      241 gtaaagttcc gcagaagcat ccgcaacttc aagccggaaa agattgagcg cgagaaggca
      301 gaaaggatac taaaggccgg ccgctatact gccaccgcca agaaccggca ggcgtgtaca
      361 tacgtattta tccaggagca gctagacgag ttcaaggaac ttgtctggaa ggaaatgccg
      421 tctatattgg aggaactcaa gcaaaatgcc ccggattacg ccagagcatt cgaactcttt
      481 tacctaaaat ggaagcggaa ccccaaggac gatacattct ttttcaatac gcccgccttt
      541 cttgtcatcg cctccaataa tcctttagat ggagggctgg cggcagccaa catagagaac
      601 atggctgtgg cggaaggact tggcgcgctg tacagcggct atatgatgcg ggtgatagga
      661 ttaagccaga cgctgcggga atggcttgga ataggggaga agagagtatc ctgctgcatg
      721 ctcctgggct atcccgctgt atcatacaga aggacagcac ccaggaaata tgcagatatt
      781 ctctggaaat agatagaatc tatatccatc agccttagaa ttacagaagc cggaatgcct
      841 gttctacaga agcgcgcata ttctcccggg cgcgctccgg cttcatggct tcctcaagcg
      901 tggtaacgcc gcggacgatg gggaagaacg cgtcaatacc agcctgattg caggaggcag
      961 cgtccttggt tacgcttccg gcaaaggcaa ggactttcac gttatacttt ttggctagcc
     1021 tggtaactcc gacaggagcc tttcccatgg cggtctgatg atccaaacgg ccttctccgg
     1081 tgacggccac atccgcgtct cttaactctt cttccaaccc cacagcgtcc agaatcaggt
     1141 cgattcccgg ggtaagtctt gcattcagga aactcaggaa ggcaaagcca aggccgccgg
     1201 ctgctccggc gccttctgtt tctgcataac tgcagccgaa ggtatcggcg gttatctgcg
     1261 catagtgggt cattgcctga tccagggcgt ctttctgttc ctcagtcacg cctttttgag
     1321 gcccatagat gtaggttgcg ccgctcttgc cgcagagcgg gtttgttacg tcacatgcta
     1381 cctggaaggt gcattcggcc agcctcggat tttttttagc gctgttgatg gcagcaactt
     1441 tggagagcgc ctgcgcacct tcgcccacat catttccctg actgtcgaga aagacgaacc
     1501 caagggcctt aagcatgccg atgccgccgt cattggtggc gcttccgccg attccgatta
     1561 taaagttccg gcatcccttt gtgatagcat cgttgatcat ctcgcctacg ccgtaggtgg
     1621 tggcagacaa ggggtcctgc ctgtccgtgg gaacaagcgt gattccggcg gcagaagcca
     1681 tctcgatgat ggcggttttc gtttcttcca agtatccgta atatgcatga acctttgttc
     1741 ccataggccc ggtgatcgta agatcgacgc gctcgccttt cattccttcg atcaaggcat
     1801 ccgtggtgcc ctctccaccg tcagccaggg gctttacaat gacttttgca tccggcttgg
     1861 cggcaaggat tccctcctcg actgcaatac cggcttccat ggaagtcagg cttcctttta
     1921 aggaatccat tgctacaaca actttcattt ctttgaacct cccgtgtctg ttatccattt
     1981 cgttactttg ttaaggtgag tatagcacat tagagtcaaa tggaaaatgt tccttgggac
     2041 aaaaataagc cgatttagtt gcgaaatatg ttatatagga caatattccc gcgaacactc
     2101 atccaggtat cgtatactca aatccgctga tccggtggat gcggtcaagt ttatactgca
     2161 gcgtatttag taccataaaa gtgtagttgt tagagagtaa ttaactctga catctgcact
     2221 tattttatta taataagggg agtaattggt ctaacgtcgg cttttttgga ttgccacatc
     2281 cgtcacaaaa accgttaacc aacctcttat tataagcatt cgattaagca ggtagggatt
     2341 cgctcccgcg taaccaacta aactgaatgg taataagtgt agctgggaca attactaaaa
     2401 cagttagagg aggttctgga tgataagcgt aggaattgat gtatccaagg gaaaaagtac
     2461 agtctgcata ctgaagccgt atggagagat tatgtgtagt ccttttgaga tgctgcatgg
     2521 ggagaaggag ctgaatgctc tcgatgatct gctaaataag ctagatgggg agataaggat
     2581 cgtgatggag gctacaggaa tttatcattt gcctatattg acattctttc acgaaaaagg
     2641 atatttcgta tctgttatta atccattcgc aatgaagaaa tatgcaaagg acaacagtat
     2701 tcgaggtgca aaaacagaca aacttgattc aataatgatt gcaaattacg gaatcgagaa
     2761 atggttcaaa ttacaaagat ataaaggtga tgaagaaatt tatgcagagc ttaaactttt
     2821 aggtcgcagg tatcgacact atatggaact tcacgtgaaa gcattgcagg aattgacgca
     2881 tatcctggat tatgtgatgc ctggtattaa gaagatgttt aacagttgga atgaagctaa
     2941 tggcaaggac aagctcagcg actttgtgga gcaattttgg cattttgatc taatcacagc
     3001 catgagcctt gaaaaattca cagaggagta tcttgactgg gcaaaagaaa agaaatacca
     3061 ccgaagcaga tccaaggctg aagcagtcta tgaattagct tccaatggta tttccacact
     3121 gtcttccggt accccatcga ccaaaatgtt agtacaggaa gcgatatcgg tattgagaac
     3181 tgtagatagt tctctgtttc tcattttaac acgaatgcaa gaacttgcga agaccctgcc
     3241 ggaatattca acggtcagag aaatgggcgg agtaggtgat gtccttgcag ttaaactgat
     3301 tgcagagatt ggcgatataa gaagactgca cagcgcaaag gcactcatag catgggctgg
     3361 aatcgacccg ccgccgtatg aatcgggaca gtttattggt tcaaaacgca agataacgaa
     3421 acgaggttct tcaacgctca ggaaggtcgg atatgaggtg atgagagtcc ttaagagtca
     3481 tcctgctcca aaagatgatg ctgtatacaa ctatattttg aaaaaggaaa gtgaaggtaa
     3541 aagcaagaaa catgcaaaga ttgcagggtt gaataaattt ctgcggattt attatgcaag
     3601 agtaatggct gtttatcaat agaacataaa atccgcgagt tcgtacaggc tggagcacag
     3661 agccagcctt tttgtcatac cccaaaatag attagttaaa taatttaaaa aacttgccaa
     3721 aaaatacttg acttttgtta gcaggttttt gtgaagaaat agtttctcgc ttgtctgtaa
     3781 cagggaccgc gttttagcca gaaacgcttc cttgcttctg tgccgaggat cggcagaacg
     3841 tgggagtcta tggtgtaaca gcagttggaa aatcctattt tctgcctgcc tgctgtgtgg
     3901 aagcctgcag gctgaattat cgctgtaaat tcgtagacta ttgtgatctg ttggatgaat
     3961 tgattgttct taagcgtctg gaagatctga gccgttacag aaaacggatt cgatattatg
     4021 ccagaataca gcttctgttt atatatgact ttgcaatcag tcgttactct gaggaataac
     4081 aactggttat atagttctta tagagcgctc atagccagta taaatttatc cagaggagca
     4141 aaatacgctt ctctggaata aaagaaagcg accgttgaag atggccctga ctggccggaa
     4201 aaagcggcct gagtggccgc taaatacggc tatttgcatt tttctgtaat gctgttgact
     4261 ttgttgtatg aaatgagtat aatatggtta gaatattact accactaatt caaggaggtg
     4321 tcgttatgaa tattcgtcca tccgcagcaa tcagacagaa ttacaacgag attgccgata
     4381 tgtgcagaaa aaccgcagag ccgattttcc ttaccaagaa tggcgaggga gatttggttg
     4441 ttatggatat tgaaacctat aaccgcaggg aaaagatgtt aaaactccgt gaggaattgc
     4501 ttgcggttga ggaggacagg atgcacggca gcacgggata ttctgtcggg gaagtcgctg
     4561 ccatgatgcg tagtgcaatc aaggaggcgg caggccatgg aaaaacagaa taggtatcgt
     4621 gttatcgtgt cagaacgggc gacacagatg cttgtttctc atgctgcatt tctggcgcaa
     4681 gtcagtccag aagaggcaga aaggctgacg gcagaatttg aaaagacagc aaattcacta
     4741 gaaaccatgc cgcagagatg tccgtggctc acaggggaat atatcccaag aaacgcctat
     4801 cgctttatcc tgtttgagaa acggtatatg ataatcttcc aaatcgttga tgatattgtc
     4861 tatgcggatt atgtagtgga ttgcaggcag gattacagtt ggctcatacg gtaacaacag
     4921 aataaccaga acggaaatcg tcacttaaaa caggtggcga tttttcttat aggaaattcc
     4981 gattttaagg aatagaaaaa aaggacaaga gtttaccgaa tatatgttag ataaactctt
     5041 gtctgggtat gacgatgaga cgacacggct tagaagatat aaaaaccttc cacgccagcc
     5101 tcgtcatcaa ataagtcgtc ttcatttaag aaataatcct gtgcacttgt attgccaatg
     5161 cctgttatat cctggattgt acttatttgt atggatagaa acagaagcac tattatacga
     5221 atgtttttaa gagttatcaa acaaattaaa ttaatggatt tttaaaaaaa ataaaagaat
     5281 attctaaata ttatatactt ttattgcaaa ttatcgtata atatctcata tattaaaatg
     5341 aggggcgtga tatgtatggc aaaatagaac tggaatgtga taagaaacta taaacttact
     5401 aagtctttca tttaaacccg atattggaag aaaggcgtgc atatgcgtaa gaaagtattt
     5461 agaattttat gtatcatttt ttcggcaggg gtttttatgt ctgtttttta tccgtggacg
     5521 gtgctgaatg gtgaaagcta tactattata gagttctata aacaagcagt ttttgacaaa
     5581 caattatata ccatggcaga tatgggagga agcgtttatc ttcttctgat atttttgatt
     5641 tttcctatgg tggtagggat tctttctgga gtcaaagcag tattgctggt attcaggaaa
     5701 aattactatt tgttgggaga aatcattaat atatcagaat tgatcagcgt tgccgccttt
     5761 tttgcatttc aaggatatga attgttaaca gctccttttt tttaagcaat ttttgtattt
     5821 cttgaattta tgatggaatg ctatttgtcg gatgttgatc gttttactaa tgaatgggaa
     5881 attcataaga ttaaaaatcg gacggaaaaa gaagagagga aacagagact tgcatttccc
     5941 gggaattatg atagaaggtt acgaaaaatt attcgaaaag atgcattaca tccttcgaag
     6001 gcggttgttt tagtatgcat cggtaatgga atccttctcg ggtcagcatt tgctttattt
     6061 gcagtgaaag aacaatttca gaaaaactat agcgcaaagg ctgttcttcc tacggagggg
     6121 ctaaatggaa ttttgaccaa tggacttctg gttattacta ttttttatat cttttttgca
     6181 atagcagcat tttttaatta tgtccataat catcaagaaa gaagaaattt gttctggact
     6241 ttgggaagta gagaaagact taatagtatt gcatggaaaa tggaatatga gtttatgatt
     6301 gtattgtcaa tgattccagg ctatatcatt ggtgtaggaa tttacaatct attaagggtg
     6361 atgttgaaaa aggaacttgg tgtattgata gatggaagga ctcaacttca gctttacttt
     6421 ttatcaggat tattatatct gtgtttatct ggagtaatta tttggctttc atcaattttg
     6481 ttgcgaaagg aattgcgggg agaaaaaaga aatatcagga aactttcgac tcctacgaaa
     6541 ggtgttgctg taattacggt tatgctatcg ttaggctatc tggtcttttc tatcggaaga
     6601 tatatgcaga gaagaaatgg ggaaagttta aacatctttg tgtatggtat tatattaggt
     6661 ggtatatgcg ttttatgttc cattcgactt ttggagagtt tgaatagaag aggaaaagcg
     6721 caaaactttc aagtactttt agataaaatt cctatgcaaa gcggtttttt taaagaagca
     6781 ggccttcaat ctgtggtttt tgctttccat tttattttct taggattttt gtctgtaact
     6841 atggccggaa aactttcagc accttcaccg gacacattgt ttccgcatga gtatgtttgt
     6901 atggcgtatc cagaagatga agaattattc acagaattga gagataaaaa tctggcagat
     6961 gtaaagtcat atccgatgat cagggttaca tccgtacagg gaaatcctac ggattggatc
     7021 gatattgcta ataactatta tcgtaaaatt atctggcctc agggacagca tataggaatc
     7081 tccagaagta cttatgaaag cttatgtaca gatgaaaaaa agaatatatc caacttcaca
     7141 ttgtctgaag atgaaattta tgtagtttat caggaagatt gttctgtaaa ggcccatcct
     7201 ttggagtggt atatgaatag aaggacacct tttatcaaag aagggcagcc gcttcgttgg
     7261 tataatcctt ttgctagaga aaattattat ccgccaagaa aagtgattgg gcaggagaga
     7321 aaagttttaa cgggagtatt tgaaagagga atccaagaac atattgttgt attttcagac
     7381 gattacttta atcagctgca tgatgtggac gggccatccg ttttgtactt cgttgattgt
     7441 ctagagaaaa acaaaaaaga agtagagaaa gtactttctg tttttgcatc taggcatatg
     7501 gaagattcct catgggatcg tttaattcaa ccttattaca gcaaaacaga aaagattaca
     7561 gatatggaag cagagaggaa attagaacaa atatcaactt cgatagagat gttattatca
     7621 gttttttgtg tatttatttt ctgttttata aaaatagaat ttgaacagga agagaaacaa
     7681 aagagatttc agacattatt ttgtctcgga atgcataaaa aacaagtcaa acacagtcta
     7741 tggagagaaa tttgtctgtt tatatggctg ccattgattt ttgcatatac tcttgcaact
     7801 gtagttgtaa cttttatatg gaaaatgcga tttgtaacgg gagcagaaag tagaaaactc
     7861 tggatgactc ttattattat ttggacaata tatcttttgt tgcaaatgct gttaactttc
     7921 gtattgtacc ggtatcaatt aaataatttg aatctgaaaa atggcgtgag ggggagaaga
     7981 agatgaagat tgaattgaaa gacatcaaaa aatcatatca aattcccgga caagatgaat
     8041 ttaaagtatt gaaaggaatc aattttttaa tttctcaggg agaatatatt tcaattatcg
     8101 gacgctctgg ttgcggaaaa actactttat taaaaatagt tggtttattg gacataccaa
     8161 ccgaaggaga tgtaattatt gatggcgtaa aagaaaaaga attgtggaat gatgaattgg
     8221 cagatcttcg tagaagaaag tttggattta tatttcaaga ctattttctt ttggaacatc
     8281 tcacggtact tgataatatg attttgccag ctcttttgga taaggcagag gagaaaaagt
     8341 cattagagcg tgcggaagaa ttagcaaatt atttacagat tgacaatagg ctattgctta
     8401 aataccctaa agaactttcc ggtggcgaga agcaaagggt cgcaattgca agggcgctgt
     8461 ttaatgatcc ggatatcctc ttggcggatg agccctcagg gaatctggac gaacagtcta
     8521 agaaaaatgt agaaaaaata tttaaagatc tccatgaaaa tataaataag tcaattcttt
     8581 tagtgacaca tgatttggaa tttgccaagt ggagtgaaaa atgttatcag ttacaaaacg
     8641 gggtgttggt taaaggataa atataaataa ggagataaga atgtgataga aaagccattt
     8701 attcacttgt ttaaaactac aaaaggtcaa tattgttatg atgttaataa agatgaaatc
     8761 atacaattgc cagatgatgt ttatatgtat ttagctggga aaggagaaaa aacagattat
     8821 gtaaaaactt atatagaaca gttgtacgaa aggggctatt taaagtcaaa acgagttata
     8881 acaactaaac atcctgcaac cgattacttg tcttattatt atgacacaaa attaaatttc
     8941 ttaattttac aagtaacaca aaattgtaat ttgagatgtg aatattgcgt gtattccgga
     9001 aattatcgaa cacggtctca caacaataaa aggatgtcat tgatttagct caaaaaggaa
     9061 tagatttttt gtatcaacat tctagagaaa gtacaagaat tataattgga ttttatggag
     9121 gcgaaccttt attaaaattt gatttaatca aaaaatgtgc tttttatata gaaaaattgt
     9181 tttatgggga aaaaagtaat atttacaatt acaacaaacg caacattatt aaaagagtct
     9241 attgtagaat tttttgtaga aaaaattaat ggagaattta agatataaga aaacattatt
     9301 gtcaatttta taaaaataat attagtttta atacaagtat gaaaaagaat tttttgattg
     9361 gttgatagaa aattatgatt gtgctacact aaattcaagt agatattttt tttgaaaaaa
     9421 gaaagaagtg attaagatgt gcataaatga aaaaaggaaa aatgatgttt tcctccatgc
     9481 aaagccagta gattgcgaca tttgcatgga gtaatcatag tcgcagaata gaaatgctgg
     9541 ctttgctact tgactatcac atcaaggagg aaagtccgca tgaagtattt taatgcaaaa
     9601 ctgattcttc cagacgcatt ggtaaaagaa ttacagaatt atgttcaagg tggatatatc
     9661 tatgttccta tcgaacagga gcagcaaaag cgttggggag aagtttccgg ctatcggcaa
     9721 gaattggaac aacggaatga gcaaataaaa agagagtatc agaatggcat ttctatggaa
     9781 tgcctgtctg aaaaatatgg tttatctttc tatgctgttg ggaaaattat atatcagaaa
     9841 taaccgtaag gggctgtgtt ttacagcctc ttattttata cagattggtt tgtactgtat
     9901 ggtgtataga atctctacca taatggcgat aaaataaaag aaagacataa gaaagtttta
     9961 tgaaaggtga atgttatgtg tactagattt gtttatcgtg gagatgatat gattacaggg
    10021 ttcaattttg atattgacct ctctgtatgg aaacataaag tgattgaaga aaaggagcgt
    10081 gttttttgca agcacttttt ggagaaaaat gcaaaatatt tttggagaat gttgcatctc
    10141 caaattggag aaagttgcaa ggcctcggct ggcagctatt ctgccagcta catagccatt
    10201 gcagaccata tttagttgtt atagcgtgag atatggaaac ggaagttccg agttttcatc
    10261 ttcatgtgca tgttccctga aatagcggaa ctcctcatcc agctctttat aatggataaa
    10321 atcatttaga tatctcagat cttcttctgc gcatcggtga tcttctatga gatcaagaag
    10381 ataatcattc atctcctcat agcgttcctg aaggttttga tattttttct gttctttgat
    10441 aactttttta tttttagcca ttgttacctg cctcctgact gctgattctt gaaagagttg
    10501 cattgatgct tgattcacgt aaccgattat tgatccccgg gaacagaatc agttccacat
    10561 ggtgggtgag cctgccaatc agtgctgttg tcatccgttg gtcataaaga acgttcaccc
    10621 actgtgagaa ttcaagattc gtgtttaaaa tcaccgattt ctgctcgtgt atctcagaaa
    10681 gataatcaaa cagaagctgt gaaccggtgc ggtcatacgg aacatatccg aattcatcca
    10741 gaatcagtat ccgggcactg ttaagcttct ttttcagtgc agtaagcttt ccgctgctct
    10801 gactctcgga aaagagattg ataagtccgg cagtgcggta gaatcttacc ggaatttcct
    10861 gattacatgc agacattcca atcagaatgg aaagcattgt tttaccggtt cctgttcctc
    10921 catacatgat gacatttttt cctgtatgat aaaactccag gtctaacagg ctttggaagc
    10981 tgacgtcttc cgggaaatct atctcatctg ccctgaattc ctccacgcgg tatctacgtg
    11041 ggaagccggc ggtattgagg aacttgctct tcctttttgc tgtacggtat tcaatttcgt
    11101 ttgtcaggag gtttaaaagg tattcctgcg gtgtgtctcc tttctgctcg aaagcctgtc
    11161 ctgcaaagtt cgtggacagc ttgagctgtt tgcagcatgc tgcaatggat ttttctatat
    11221 cagccatttg agacacctcc cttcttaagg gcggcatcca gcattttcag atcatttctg
    11281 aacggaatga ccttctgctg tggcagtaaa actttgtttt caagcggagg cagaagcggt
    11341 acatctgcat aggttcgcct gtaaaggctc tgcagactgt ccggatctgt ggcattcagc
    11401 cggactgctt cgtcaactgt tctgacagca ctagcaaacc cggttctttc cgtaagttct
    11461 gcaagcacct tcaggacacg tccgcgttcc ttgctttcgc atttatccat gtatatctgc
    11521 atggtttgtg gcatcatgtc atatatgccg ctgtttcgaa gagaacgggg tttcctggcg
    11581 atatatgtaa ggtatggcag ccagtccatt ctttcatgtt cattgccgta aaggcgctta
    11641 tgacgcacca cttcgtgcat atctttgtcc atgacaatca catcagagga tgtaatcttg
    11701 agatttacaa tggactcaca gaaagccggt gaagcagaat aacggtgctt tcctgcgtca
    11761 agagtaaact ttccatattt atccgttgtt gccgttgtgt aaagtgccgt atcaaacgga
    11821 acggaaggaa gcggcagtaa acgagcctta tcttcttcaa acagtttact gataaagcgg
    11881 tcatcatcgt catcatagtg ctcacgctgc atatcgattt cacaacgatc cagaagatgc
    11941 ttgttttctt tcacaagatc atcaaagcgg ggtaccggta caagttcgtt gcggcgcagg
    12001 tagccaacct tgttttccac gtttcctttt tcccatccgg attcaggatt cataaaaacc
    12061 ggcttaatgc ggtagtgttc acaaaagcgt tgaaaccgct ctgttacatt acgcccgcca
    12121 cctttgatga tttcggtaac aatggttctg gtattgtcaa accagatttc cgtgggaaca
    12181 ccaccgatgt gctcaaatat ggcaaccagt ccttccagaa gacattccat gttttcgcca
    12241 taattaagct ggaggaaacc tccgttactg tagggaaaac tgagcacaag gtacttagcc
    12301 tcgtgatgaa gcctgtcatt ttcataaaaa tcggctgttc caaagtctga ctgggcttcg
    12361 ccgggatgat gattaagagg gatatagcca tcggttcttt ttagccgtag ttcctctttc
    12421 ttctgtttga cgtataaggc aacaagccga taactgcagc cgaaaccatc tgcttcatcc
    12481 ttgaggcgtt taaatactct tttggctgta tgccgttgct ttcttggtgc aagcttgtct
    12541 gcctgcagcc attcatcaat caaaggtttg aatgggtcaa gcttggattc gtgaacctct
    12601 gatgatgcag gtttgggaga tggattgtta aagtcctcca tatccacata ttttttgacc
    12661 gttttccagt taaggccggt ctcagatgcg atttcagaaa tgttcttatc ttgccggtag
    12721 aacatatctc tgatatgatg tatctgatcc attgtagttg acattctcct ttcctccttg
    12781 tctttattgt ttggactaca ataaagataa ggttaatggt ttttggatat acctgcaatg
    12841 gatcttttca tgggaatgct catacttggt ggctgccact caagcgctac accgttcctg
    12901 agcgcttcta gcgaatgcct tgcaactttc tccaatttgg agatgcaaca ttctccaatt
    12961 cccgtttgca actttcggta attctatttt acaataaaca tataatgata gtagatataa
    13021 acaatctttt tttgataata aaaacagcat agatttttca gtatcttttt ataactatca
    13081 cgaaccgtca atatatccct gtttatcagg gtttggcggt tttttctttt tggcaggtct
    13141 gccgtggaac tgcacacaat ccctcatatt tccaccctca aacgttgtac aaatcgttgt
    13201 aaatcatgct atcaggcttc gcatttctct gtttgctcct gcttctgacg catgagcgta
    13261 taaatccagc gttatcgtta tgcttgcgtg ccccatgata tactgtaaat tcttcgggtt
    13321 catgttcttt tgtgcaagct gtgtgcagaa cgtatgtctt aagctgtggg gcgttatcct
    13381 cggcaacggc gttttctcat gattcttgtt gtacttcctg acaataccgt tcagcataaa
    13441 tttataactt ccctcctgca taggatagcc gttgggacta aggaacagaa aattgcggta
    13501 gccgtctatc tctttgattt ttggcttctg tctcctgttc agcactcgct gaaaggcttt
    13561 ctctgtttct tcactcatag gcacgttgcg gataccgctc tttgtctttg gctcggctat
    13621 gtagaagccg tctttgtcct taagtagctg atgagtgata cggattgcat ggttcttgaa
    13681 atctatatcg ctccttgtca gtccgcacag ctccgagata cgcaagcctg ttttcagcag
    13741 gataagcaca tcatcatgat acttactgta aacattgtca tgcttcataa aatctaacag
    13801 ccttgcttcc tgttcttcgc tcaatgcgac tttcggcttg ctgtcgtcct ctatgacctc
    13861 gcttagctgg aaatcaaacg ggttcttcct tacgcagtcg tcctctatcg ccatgtggaa
    13921 tgacgctttc agggaacgct tgtagttgtg gattgtcttg taggaaaagc cattctcttt
    13981 cattctgacc gcccattcct tagcgtctga cggctttatg ctgtctatgc tccttgctcc
    14041 cagcttgtcc tgtttcaatg cttccatgag gtatttacgc ccctgctgtg tgcttttctt
    14101 cacgttagga cgctgtgcgt tctttttagc gtatagctgg cacaaggtca tcttgcttcc
    14161 ctttgtgtcg ataccgtcaa ataaatcacg ctgtatgata cgctcctttt cccgtaggga
    14221 taagtcctct cgctttcctg ccggtgtctt atccgtaggc aacagtttcc atgcgtagac
    14281 atactttgtt tccccctgtg cgtccacata tttataggtg tacctgccgt cctttctctg
    14341 gctctctcct ctgtttaaga tacggttctt gttatcccgt ctttttgctg atgacatctt
    14401 tcttaactcc tttccaagta agaaagagcc ttgctgtaac gacttataca catcttatca
    14461 cacacaaggc tctttttcac tagatttgtt ccaatcggtc aatgactttt tcaaatttct
    14521 ttttcttgat aagcatacgg tttccgttca tcacgacaca ttcctctttg tattcgttgg
    14581 caagctggcg gagcttgttc tccccgatac ggaaatagct ggacgcttcc tctatcgtca
    14641 tgaggtatct ttcccataac ggcatactca aatcgtgcat agatatggca cctcctttcc
    14701 ttgttgtctg gaagcggtca gacggcttgt gtcatagccc acgggaattg cacccctaca
    14761 tggttctcat gtagccgtac ccattgcgtg cgacgcttca aacgctcaag ctgtggctgt
    14821 acgggagtat cattatcaga caggacaggt catggctgga aaaggggaca agccttttct
    14881 aggaacacag atagttttcg ctcgcttaca gggcaggaga taaggtcgtg gcgtatctgc
    14941 tcgggcggct cgctgtctgt ctaacgtatc tgaccgcttt attcagtttt caaagaacac
    15001 ttgaaagaag aaatttccct ttacactatt agtacaaacg gaaaggtgca ttttggcaaa
    15061 aatcgcttga ttttcttctt ttcacatcat atagggacgt gaaacggctt tttgcttcca
    15121 tttttgaaaa gaaatttccc tttctgctcc atatagggat agcaacaggc gatttcatga
    15181 ccaaatccag aaatttttta tttttcttct tccacaacat atagggacag caaagtaccg
    15241 tttgttaagt taggaataaa aaaaatcaag gttcttcttt cactccatat ctgtccgcta
    15301 aatgcctgat tgtttccaaa atcaaaaaaa tttttaaaat ttcttctttg cacctaatat
    15361 ctgtccagca ataggcggtt tgctaagtta ggaatgaaaa aaattaaatt tcttctttcg
    15421 ctccatatct gtccactgaa tgtccatttc atgacttttg gggggatttc ttaaaaaatt
    15481 ctccaatcaa aaaataccgc catttcttta agaacagcgg tatcagccta ttatcacatc
    15541 ggatatgtct gttgtcattt gcttgatttt caattcctgt ttttccgtca atctggtctg
    15601 cctgtcgatt gtttccaagt agttcgcccc tgtttccttt tcaatctcct ttatcatcag
    15661 cagggaaggc atgacctgcc gttccagcca gcgtatggtc ttgtccatgt tgacggcaac
    15721 aggcgtcatg atgaacggca gagaagcggt catgttttca ataaatatat cccacaggat
    15781 atagtcggga aagtccatct gcatgaggat aaggcttgta actgtctgtt cgggatttct
    15841 tgagaaaaca agttcttcta ctgcctgtcc tgccttttca tttttcagac ggatttcaag
    15901 acggttcttg atgtcggtct gtatgccctt gttcctctgc tccttttctt tctcgtatag
    15961 gcagaagtag atcgggctgt tctttgagcc gatataaaag gtctttgcgg tatctccctt
    16021 tgttcccgac agttttccgc tgtccacgcc ctcatatttc cttgaacgtt tccatacctt
    16081 gttggcgtaa tagcgttctc ttaaaatttc tatgtccagc agcccgccca tgtcattgat
    16141 tgccaagtcc agacgcttaa agataccctc atagtccatg caacggctca ggaagtgata
    16201 ccagcctgtt ttccttgcct gtaagacgtg ttccaagtgc cgacaaccca tgccctttaa
    16261 ttccagtaaa acgcccatag aagcgtcttt ggaagctgta acgataatct cgccatagcg
    16321 gtataattcc tcatagccga acagcccgta atcctcatgg ataaagtatt cagctttcat
    16381 tgccagcacg tttttgataa tctccagtgc gtccgtcgta gggaagcgga cacgcaggta
    16441 atcaactgtc agcgtaaagg gctgcgtgca gttgcaatag tcgagataat gcaggagcgt
    16501 gtgcttcatt tccttgctgg ctcttgtttt cccattctca atttcattta agttctgtct
    16561 gctgatatgc agttcctttg ccagtctgct ttgagaataa ccgcaggcgt tccgttttac
    16621 tttcaatact tcgataaatt ccatatcatt catgttcatt cctccaatca aaaaaggcat
    16681 acgcccatag gagcatacac cttgtatcat gtgttttctt gtgtcaatat gctgttttca
    16741 acctgtcggg tagaatagac agggtgtgat atgcagtaag tccttataac tttgtaaatc
    16801 gtctcatatc gggatttttt tatgtgttct gtgtcttgtt tcttgtaata gtacccccct
    16861 gttagataac gggggcttct aaggctcgct acgctcgccc aaccgccgaa gtgaaccgcc
    16921 ccctcgccag ctttgctggc gtggcgctat gtcttacgac cgccaccgtg gtcggctcac
    16981 cccgtcggtt gttgagattt taaacgtatc ttccacacaa actgggattt gtgtcattat
    17041 tcttttttat atttttgtct agctgctaca actataataa acaaaatcaa tgcaacacca
    17101 ctaatagaat agtattctcc agtagtccaa taaaatattg cacatattat taaaaccgcc
    17161 aataaaacaa tcgtcataat gttaaaaaat attttcattc tgtattttct cctttccaaa
    17221 accaaatctt gaactcgacc tttcaaattt cgatttgttt ttacttgatt atatcatgaa
    17281 gttataagta ttgtcatttc ttttctgctt ttgaaaagat acttattagc ctatattttg
    17341 taaagggtgc tgttcagcat tgcttacgca acaagccctt gacaaaccat agactaataa
    17401 gttttagagt aatcaagcag aaatgaaata gtctgctgtt acactgcata gaaaaagaca
    17461 ctctttttca agtgtcattt ttccataact ctgtatttct ttgtataagt cgttacatca
    17521 ggttctttca tttgttgtaa tttcgttgta aattgcttct ttttctttta tcggatttgt
    17581 tgatagatat agtgtttatg cgggtattca cagtttttta actgttttta gacataaaaa
    17641 aattctatcg caaatgacac aaaaaacgct tatggatgaa ttgattaagt tggcaaaaga
    17701 aataaaaaga aatattatta aaaaatattt gaaagaaaaa acaggaaaaa agatatttgt
    17761 agatactatt gaaaaatata aatctggaat tgtatattgg ctgccaacct cacattttta
    17821 tgtggataag gatattgaaa gtattttgca aacattagaa ttgtattata tcgtaagtaa
    17881 atttaatgag ggaagttcta gaaaaccagg tgttaaagtt tcatattatg ggttaaatta
    17941 tggattgtgc ttagaaaata caatagatta tggaaagcct gaattgagac gcacttacga
    18001 ttattggagg caaaatgaat tcgattattc tgattttatt ccagcagtta ttaataaaat
    18061 agaagtacca atatgcagga aatgtggtta tagatataca gataaatcgg agtataaagt
    18121 agcaaaaaaa tttggatact gtttacaacc tggattctcg gactaa
//
