LOCUS       NZ_CP009108.1          10327 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP009108.1 Bacillus altitudinis strain GR-8 chromosome, complete
            genome.
ACCESSION   NZ_CP009108
VERSION     NZ_CP009108.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:59:09
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3257880
            Orig. end    :: 3268207
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10327
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[3262880:3263207](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5327
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10327
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10327
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="8"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(291..572)
                     /locus_tag="ctg1_3263"
                     /transl_table=11
                     /translation="MHSLDDTMHLHVGYYEQGVDIEGMFFKSLDTGKWLLFFDHTWYGI
                     TLLKHYEKYEDLGLLIGEYSIEDDKIEDEGNQLFERFLKENGILKSME"
     PFAM_domain     complement(315..563)
                     /aSDomain="DUF3986"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13143.8"
                     /description="Protein of unknown function (DUF3986)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3263_0298"
                     /evalue="2.30E-12"
                     /label="ctg1_3263"
                     /locus_tag="ctg1_3263"
                     /protein_end="86"
                     /protein_start="3"
                     /score="47.8"
                     /tool="antismash"
                     /translation="LDDTMHLHVGYYEQGVDIEGMFFKSLDTGKWLLFFDHTWYGITLL
                     KHYEKYEDLGLLIGEYSIEDDKIEDEGNQLFERFLKEN"
     CDS             complement(618..1028)
                     /locus_tag="ctg1_3264"
                     /transl_table=11
                     /translation="MFLYYGPTGAPVENPGEEWMKEIFFHKDEDYWKQGNGESSIEVDE
                     DWETESLVFFYHKPYGFFLMRYPDFLVPFKKVEKIETIKHVVAGAPLYVPSCSYVDRHQ
                     AYEIVQHFLKTKSIPDSVEWVELRTINFQQNL"
     PFAM_domain     complement(651..860)
                     /aSDomain="Imm1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14430.8"
                     /description="Immunity protein Imm1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3264_0299"
                     /evalue="1.50E-05"
                     /label="ctg1_3264"
                     /locus_tag="ctg1_3264"
                     /protein_end="126"
                     /protein_start="56"
                     /score="25.8"
                     /tool="antismash"
                     /translation="HKPYGFFLMRYPDFLVPFKKVEKIETIKHVVAGAPLYVPSCSYVD
                     RHQAYEIVQHFLKTKSIPDSVEWVE"
     CDS             complement(1049..1477)
                     /locus_tag="ctg1_3265"
                     /transl_table=11
                     /translation="LKRVDVVSALIYDMDEHILMVKNVKGYWEFPGGAVEKGEHLQPAV
                     IREVREETGYVIKVNELHSVREILFQDNMHHALIFTFFAEIIGGEMNILDPDHDIEEVK
                     WVSNQDAEKLNPQLFSMLKLNKQTRAFYTFEGKRTRDQ"
     PFAM_domain     complement(1130..1471)
                     /aSDomain="NUDIX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00293.30"
                     /description="NUDIX domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3265_0300"
                     /evalue="2.10E-19"
                     /label="ctg1_3265"
                     /locus_tag="ctg1_3265"
                     /protein_end="116"
                     /protein_start="2"
                     /score="70.0"
                     /tool="antismash"
                     /translation="RVDVVSALIYDMDEHILMVKNVKGYWEFPGGAVEKGEHLQPAVIR
                     EVREETGYVIKVNELHSVREILFQDNMHHALIFTFFAEIIGGEMNILDPDHDIEEVKWV
                     SNQDAEKLNP"
     CDS             complement(1706..1933)
                     /locus_tag="ctg1_3266"
                     /transl_table=11
                     /translation="VVLIRFISLVMLTVVGLAFVINNVPGLMLPIYILSMIGLMFCLGH
                     IALHYLQRIRYLLYDEKQLKENQINKPPAK"
     CDS             complement(2035..3447)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 115.5;
                     E-value: 4.9e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3267"
                     /transl_table=11
                     /translation="VSIKGKVILVLCGLAIVIGIAGFYHNQQASGTERKKVEQDASYKQ
                     VEIVTLVNDGKFMRYAVNYPLFHQEKLDQEIKRFAETALEKFKTSFSQASDVNEEKRYE
                     LNIDYEIIHYAKQTVAIRFNTYEVKGGKQGVNQTKVMNFDFKKQTFLSINDIFLSKKDN
                     FQKLSHMTFEELKKDRTLAENQPLLKRGTSPEAKNYQYFAIKDRFIEFYFPRGQIAPNH
                     QGPQVLAIKKTLLKGMLKPEYINKEKNKNEKKEPIAKRKIVKLPKQRVINPHQKAIALT
                     FDDGPNPSTTSKILTALKENKGHATFFVLGSRVQYYPDMLSEIRKGGNEIGNHSYNHPL
                     LTRLPLKQAVKQVEDTQQIIEKASGFTPTHFRPPYGGTNGQINEALHMKVTLWDVDPED
                     WKYRNSQYVANYILTHASSGETVLMHDIYDTSANAAVTIIKELTKQGYQLLTVSELEQW
                     KEAREKKGESNR"
     PFAM_domain     complement(2290..2631)
                     /aSDomain="Polysacc_deac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01522.23"
                     /description="Polysaccharide deacetylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3267_0301"
                     /evalue="7.60E-32"
                     /label="ctg1_3267"
                     /locus_tag="ctg1_3267"
                     /protein_end="386"
                     /protein_start="272"
                     /score="110.0"
                     /tool="antismash"
                     /translation="PHQKAIALTFDDGPNPSTTSKILTALKENKGHATFFVLGSRVQYY
                     PDMLSEIRKGGNEIGNHSYNHPLLTRLPLKQAVKQVEDTQQIIEKASGFTPTHFRPPYG
                     GTNGQINEAL"
     CDS             complement(3602..4156)
                     /locus_tag="ctg1_3268"
                     /transl_table=11
                     /translation="MSQPVMRITLAAGPNSELESFALRAALENFGAKVDMHWIGRPNDL
                     INVLSGRNRGETDFILLSFHGEEGAFLMPELGEDVYEEGEPRGAAFGADDIKWYASLNG
                     VHIICTGCTLGEKKVAEAFLETGAISYTAPDDYIDGNASFIFVLTMLYELVNNSKTVRA
                     AFDQARSIDEETKLFQLYMQK"
     CDS             complement(4110..4712)
                     /locus_tag="ctg1_3269"
                     /transl_table=11
                     /translation="LEVSIHSDGGDFLNIRLLTPEDAQEYANLRLEALRLNPESFAMSY
                     EEEKLDTKNKYKARFASTQSMWTFGAFHQGQLVGSVTLIQETLQKLKHRANVAAMYVTA
                     NGRGKGIGKALLTKLLSFAREKKDIEQIYLTVVTTNDPAKYLYMSVGFKSYAVEEKALK
                     INGAYVDEEKMMLCLSSFGGDINEPASHAHHIGSRTK"
     PFAM_domain     complement(4257..4595)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3269_0302"
                     /evalue="9.20E-14"
                     /label="ctg1_3269"
                     /locus_tag="ctg1_3269"
                     /protein_end="152"
                     /protein_start="39"
                     /score="51.8"
                     /tool="antismash"
                     /translation="SFAMSYEEEKLDTKNKYKARFASTQSMWTFGAFHQGQLVGSVTLI
                     QETLQKLKHRANVAAMYVTANGRGKGIGKALLTKLLSFAREKKDIEQIYLTVVTTNDPA
                     KYLYMSVGF"
     CDS             5001..5327
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IId"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3270"
                     /sec_met_domain="Bacteriocin_IId (E-value: 1.2e-24,
                     bitscore: 83.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETRNEIKLHVLFGALAVGFLMLALFSFSLQVLPVADLAKEFGI
                     PGSVAAVVLNVVEAGGAVTTIVSILTAVGSGGLSLIAAAGKETIRQYLKNEIKKKGRKA
                     VIAW"
     aSDomain        5112..5324
                     /aSDomain="TIGR03651"
                     /aSTool="tigrfam"
                     /description="circ_ocin_uber: circular bacteriocin,
                     circularin A/uberolysin family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3270_0054"
                     /evalue="2.10E-22"
                     /identifier="TIGR03651"
                     /label="ctg1_3270"
                     /locus_tag="ctg1_3270"
                     /protein_end="108"
                     /protein_start="37"
                     /score="77.2"
                     /tool="antismash"
                     /translation="DLAKEFGIPGSVAAVVLNVVEAGGAVTTIVSILTAVGSGGLSLIA
                     AAGKETIRQYLKNEIKKKGRKAVIAW"
     PFAM_domain     5124..5324
                     /aSDomain="Bacteriocin_IId"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09221.12"
                     /description="Bacteriocin class IId cyclical
                     uberolysin-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3270_0303"
                     /evalue="3.50E-12"
                     /label="ctg1_3270"
                     /locus_tag="ctg1_3270"
                     /protein_end="108"
                     /protein_start="41"
                     /score="46.4"
                     /tool="antismash"
                     /translation="EFGIPGSVAAVVLNVVEAGGAVTTIVSILTAVGSGGLSLIAAAGK
                     ETIRQYLKNEIKKKGRKAVIAW"
     CDS             5396..7165
                     /locus_tag="ctg1_3271"
                     /transl_table=11
                     /translation="MLYPLLSLLLSIRLEQQYSNIAQYVIRKIPFLKSFSSKQYIFFSC
                     ILDIIFGCMIVFVISSFLYSPVYQIEWESAFVMFLFLFSIVKGIESYRRTHLLPFKELI
                     QLAPVSSRQLFQTLLFSELIWLVFTSLSTYLIYFLFQYDIVQTHDLAFWLKHVNVLLTS
                     IFLFIISNKIFGAYIYNIVVKKIGAIRVLFFASIALLFFFFGRVLILNIIFPFYHTFQQ
                     LFQSISSLAEDSFWITLSNKLISLYQHDLQQMHHALFSDGSVFLQFQALFNSPITLIVV
                     ILGSALVMRSPVRWIPTEKDQDQSSKHFRDLFYWYFQVLHKIQGLLFRQNVLIQKDIKL
                     LKEKRWLLSKEFFNYMFMSYEAFFYIGVFTGLISIIDHQALQIQLLFTLNIMILANQSY
                     EMRMLTPSIFALSAEKKNIWLYELSQISLLQFFLSKIQLFYCLFSIPALCLLFINLSIM
                     TVYQLFHVQMLIQLVALGIGFFIFPLIQLYLFPITTKFNFIHEHEIGTTNEELEIIDKG
                     QAFARNFLVLPFMYYLILTSFLPILQQSSGLVNVLFAIYFAIVSVICWILCRKTIYKGI
                     EYVEKNKIFSIGE"
     CDS             7167..7667
                     /locus_tag="ctg1_3272"
                     /transl_table=11
                     /translation="LILRLGYLYAGVFIAALLIGCLLPYDQIPYLKKDEDMFFLSIFSN
                     NLQVGLAILGIGAFTGGIMSAGILFYNGYIIGKLIQFLIAQHEVQQLFTGLMPHAFVEV
                     LGLILFSIVSAFPFIYLYRFMKGKAIDVRKLTRTVIQLIFAAVVLLLIASLLEEYVSHV
                     HLS"
     PFAM_domain     7200..7649
                     /aSDomain="SpoIIM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01944.19"
                     /description="Stage II sporulation protein M"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3272_0304"
                     /evalue="4.50E-20"
                     /label="ctg1_3272"
                     /locus_tag="ctg1_3272"
                     /protein_end="161"
                     /protein_start="11"
                     /score="72.4"
                     /tool="antismash"
                     /translation="VFIAALLIGCLLPYDQIPYLKKDEDMFFLSIFSNNLQVGLAILGI
                     GAFTGGIMSAGILFYNGYIIGKLIQFLIAQHEVQQLFTGLMPHAFVEVLGLILFSIVSA
                     FPFIYLYRFMKGKAIDVRKLTRTVIQLIFAAVVLLLIASLLEEYVS"
     CDS             7689..8234
                     /locus_tag="ctg1_3273"
                     /transl_table=11
                     /translation="MELLLRPKQFFNQHQSIKTIVGLVLLSLFVSTVFLTFFIIDLLVE
                     EPLSAGKQLASIVFIFLLTIPLYFILNFLGTVVTSIYMYFFHKTFILRKMYFVILLYNA
                     FLLLVNSAAIYCVMVLDLDHYFIIIQAISFLINLYLLRILYDGIIYYAEGSKKAALATV
                     ILYMLVTTVFVIGGFING"
     CDS             8227..8895
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 132.7; E-value:
                     2.8e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_3274"
                     /transl_table=11
                     /translation="MASLQVSQLSFRYETTEESSPLLDQVSFHLKEGDRACIIGKNGSG
                     KSTLLKIIAGLLPSVSETILLNEQHHPRSALFKGLVAYIPDKPLVYDALTGIEHMTLIQ
                     SLWKMNQSEKEVYKKTFLSLCDAFDLTHALKMPVKQYSLGMRYKLFFNCMAARSPELII
                     LDEPFTSLDEASQMQSISLLKEEFSDQCVLFTSHQRYLYSELGNRFFELDHGQLNEIER
                     "
     PFAM_domain     8293..8730
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3274_0305"
                     /evalue="1.70E-21"
                     /label="ctg1_3274"
                     /locus_tag="ctg1_3274"
                     /protein_end="168"
                     /protein_start="22"
                     /score="77.2"
                     /tool="antismash"
                     /translation="LDQVSFHLKEGDRACIIGKNGSGKSTLLKIIAGLLPSVSETILLN
                     EQHHPRSALFKGLVAYIPDKPLVYDALTGIEHMTLIQSLWKMNQSEKEVYKKTFLSLCD
                     AFDLTHALKMPVKQYSLGMRYKLFFNCMAARSPELIILDEPF"
     CDS             complement(8948..9241)
                     /locus_tag="ctg1_3275"
                     /transl_table=11
                     /translation="MSRNRLDNFFFGPRRGNHGEVETVVSPTRQIVNTTTNVQTIRKIH
                     PTHITNVNKNIKRIENYYPVTQSTRNEYIVEEYDCGSDIKNPCCRPVKRCKW"
     PFAM_domain     complement(8987..9178)
                     /aSDomain="Spore-coat_CotD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11122.10"
                     /description="Inner spore coat protein D"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3275_0306"
                     /evalue="9.70E-16"
                     /label="ctg1_3275"
                     /locus_tag="ctg1_3275"
                     /protein_end="85"
                     /protein_start="21"
                     /score="58.5"
                     /tool="antismash"
                     /translation="ETVVSPTRQIVNTTTNVQTIRKIHPTHITNVNKNIKRIENYYPVT
                     QSTRNEYIVEEYDCGSDIK"
     CDS             9425..9742
                     /locus_tag="ctg1_3276"
                     /transl_table=11
                     /translation="MKTRHKLFSFFILLVVIITLPLLSPMVFTNATERGAIRHAIYQEG
                     YPYQSYFAILQKKDDVDPQYGQLYDVYWQAWKSETGMTPSVCYSKKVEDHEYKVSCGTA
                     P"
     CDS             9779..9991
                     /locus_tag="ctg1_3277"
                     /transl_table=11
                     /translation="LINTTQTIERNKLDIALELTQLHLNRYEANHPDQLSEIYAKYYAL
                     LEVLDVSSSDQLMDLLPDELKQILD"
ORIGIN
        1 aaacgcagcg ggaaatagcc aaggagctcg ggatatcaag gagttatgta tctcggatag
       61 agaaacgcgc gctgatgaag atgtttcatg agttttaccg agcggagaag gagaaacgga
      121 agcgggagaa ggggaagtga tttgaaagat ataaaaaaat ccattcattt tgggttgata
      181 aaaaaacaga ccacattagg tctgtttttt attttgacca ttctttgttt cttatataag
      241 actgaccctt attagattta aaaatactct aaaggctaag aaatatctgt tcactccatt
      301 gacttcaata tcccgttttc ttttaaaaaa cgctcaaaca actgatttcc ttcatcttca
      361 attttgtcat cttcaatgga atactcccca atcaacagcc ctaaatcttc atatttttca
      421 taatgcttta aaagcgtgat cccataccat gtatgatcaa aaaataatag ccattttcct
      481 gtgtctaaac tcttaaaaaa catcccttca atatcaacac cctgttcata atagccaaca
      541 tgtaggtgca tcgtatcgtc taaactatgc atttcatccc ccttaacacg tgtctatctg
      601 gttccctcgt aaaaaattta tagattttgc tgaaaattaa tcgtcctcaa ctccacccat
      661 tcaacactat caggtatcga ttttgttttt agaaaatgtt gaacgatttc ataagcttga
      721 tgtcgatcga cgtagctgca tgaaggtaca tacaatggtg cgcctgcaac gacatgcttg
      781 atcgtttcta tcttctctac ttttttaaaa ggaaccaaaa aatctggata tctcatgaga
      841 aaaaagccat aaggtttatg ataaaagaaa acaagacttt ccgtttccca atcttcatcc
      901 acttcaatag aagattctcc attcccttgt ttccaatagt cttcatcctt atggaagaag
      961 atttctttca tccattcttc tcccggattt tccactggag caccggttgg tccataatac
     1021 aaaaacattc cattctctcc ttgttcattt attgatccct tgttctcttt ccttcaaatg
     1081 tgtaaaatgc acgcgtctgt ttatttaatt ttaacatgct gaataactgt ggatttaatt
     1141 tttcagcatc ttggttgctt acccatttta cttcttcaat atcatgatca ggatctagaa
     1201 tattcatctc tcccccgatg atttccgcaa aaaacgtaaa aataagtgca tgatgcatgt
     1261 tatcttgaaa aagtatttct ctaacagaat gaagttcatt tactttaatc acatatcctg
     1321 tttcttctct cacctcacgg atcacagctg gctgcagatg ttctcctttt tccactgcac
     1381 caccgggaaa ctcccaataa cctttcacat ttttcaccat gagaatatgt tcatccatgt
     1441 cataaatcaa agctgacacc acgtctactc tcttcaactg aatcctcctc acccattgtc
     1501 gaaaatataa aacgagctgt tcatatcaat cttttctcat tatactgtat ccttgttacg
     1561 aaagattgga gggcttagct cgtggatcat tatgctctta ctgattgtcc aaatcagatt
     1621 tacgaggaac atcgtctctc ttttgagaca attcaaggag tcaaacgaga aaatcattga
     1681 aaaacagaca agtaaaaaac ctccttcatt tagcgggagg tttgtttatt tgattctctt
     1741 tcaattgttt ctcatcgtat aacaaatatc tgatacgctg tagataatgg agcgcaatgt
     1801 gaccgagaca gaacataagc ccgatcattg aaagtatata gatgggcaac atcaaaccag
     1861 gtacattgtt tatgacaaaa gccaaaccaa ccactgtcag cataacgaga cttataaatc
     1921 ttatcaatac cacttgaagt cccccttcat attcaccata acagattttc cctttatttt
     1981 catgacctgc ctaaaaaaga tgcgaatcca ctaagattca caccaaaagg ggtattacct
     2041 attcgactca cctttcttct cacgcgcttc cttccactgc tcaagctcag ataccgtcaa
     2101 taattgatat ccctgttttg taagttcttt gataatcgtg acggctgcgt tggctgaggt
     2161 gtcatagatg tcgtgcatta agaccgtttc accgctagat gcatgagtta gaatgtagtt
     2221 cgcgacgtat tggctgtttc gatatttcca gtcttcagga tccacatccc aaagggtcac
     2281 tttcatgtga agagcttcgt tgatttgccc gtttgtcccg ccatatggtg gtctaaaatg
     2341 agtcggtgtg aacccgctcg ctttttcaat gatttgctgc gtgtcttcta cttgtttgac
     2401 cgcttgtttt aaaggaagtc ttgtaagcaa agggtggtta taggaatggt ttccaatttc
     2461 atttccaccc tttctgattt cacttaacat atcgggataa tactgaaccc tgctgcctaa
     2521 tacaaaaaat gtcgcatgtc ctttgttttc ttttaaagct gttaagattt ttgaagtcgt
     2581 tgatggattt ggtccatcat caaatgtaag ggcaatggct ttttgatgtg ggttaattac
     2641 tcgctgtttt ggcagtttta cgatctttct ttttgcgatc ggttcttttt tctcgttttt
     2701 gttcttttct ttattgatgt attctggctt taacattcct ttcagcagtg ttttcttaat
     2761 cgctaacact tgagggcctt gatgatttgg agcgatttgt cctcttggaa agtagaattc
     2821 aataaaacga tctttgatgg caaaatactg atagttcttc gcctcaggag acgttccccg
     2881 tttgagcagc ggctgatttt cagctagcgt tcgatctttt tttaattcct caaaagtcat
     2941 atgagataat ttttgaaaat tatccttctt tgatagaaag atatcgttga ttgataaaaa
     3001 tgtctgtttc ttgaaatcaa agttcatcac cttcgtttga ttgacgcctt gctttccgcc
     3061 cttcacttca tatgtattga atctgattgc gacggtttgc ttggcataat gaatgatctc
     3121 ataatcgatg tttaactcgt atcgtttctc ttcattgaca tcactcgctt gactaaacga
     3181 tgttttaaac ttttctaacg cggtctctgc aaatcttttg atctcctgat ctagtttttc
     3241 ttgatgaaac agcggatagt tgacagcata tctcatgaat ttcccgtcat tcacaagtgt
     3301 gacaatttca acttgtttgt agctcgcatc ttgttctact ttttttctct ctgtcccgct
     3361 tgcttgctga ttatgataaa atccagcgat tccgatgaca atcgcaagtc cgcatagaac
     3421 aagaatgact ttccctttga ttgacacaat gattctcctc tcgtgatgcc gtcctgtcta
     3481 aatggcgtgt gtttgtagga tagacttttc gaagcccctt tttagtttgc aaaaaacaca
     3541 cttgtcacat tttcgacata ttttacgaga gacatataaa aagggcttga ttgctcagcc
     3601 cttatttttg catatacagt tggaataact ttgtttcttc atcaatagag cgtgcctggt
     3661 caaaagctgc tctgactgtc tttgagttgt tcaccagctc atacagcatg gtgagaacaa
     3721 aaataaatga cgcatttcca tcaatgtagt catcgggcgc tgtataggat atcgcccctg
     3781 tttctaaaaa agcttctgcc accttttttt cgcctagtgt acagcctgta catataatgt
     3841 ggactccatt taacgaagca taccacttta tgtcatccgc accaaaagca gcacctctcg
     3901 gctcaccctc ttcgtataca tcttctccta actccggcat gagaaacgct ccttcttctc
     3961 cgtgaaagga taaaagaatg aaatccgtct cgcctctatt cctcccggat aaaacattaa
     4021 tcaggtcatt cggtctgcct atccaatgca tatcgacttt tgcgccaaag ttttcaagtg
     4081 ctgcacgaag cgcaaaggat tccagctcac tatttggtcc ggctgccaat gtgatgcgca
     4141 tgactggctg gctcatttat atcccctcca aacgatgata aacatagcat cattttttcc
     4201 tcatctacat atgcaccatt tatttttagt gctttttcct ctaccgcata cgacttaaat
     4261 ccaacagaca tgtaaagata tttggctggg tcatttgttg tgaccactgt taaatatatt
     4321 tgttcgatgt cttttttttc gcgtgcaaaa gaaagtaatt ttgtcaggag cgccttccct
     4381 attccttttc cgcgtccatt agccgttaca tacatcgctg ccacattggc acggtgcttt
     4441 aatttctgca aggtttcttg tatgagtgta accgagccga ccagctgacc ttgatgaaag
     4501 gcaccgaatg tccacataga ttgtgtagag gcaaaacgag ccttatattt attcttcgta
     4561 tctagcttct cttcctcgta actcatagca aaactctctg gatttaatcg gagtgcttct
     4621 aatctcaagt tcgcatattc ttgagcatct tctggtgtta acaatcgaat attcagaaaa
     4681 tcgcctccat cagaatgaat tgatacttcc aattttatct tgaaagaagc ttttgatcaa
     4741 agaatattgg ttcatttaca tatagcacat ttcttataga cttttaggct ctctttcgtt
     4801 tttgtgaaaa caaggtcatt ttgatcatgt tcactcgata ttccctatcc aaaacgattc
     4861 ttttctcact tatcttttca cttattttat attaacctat aactaattca tgaaaaaaaa
     4921 gaaaaaaaag gattgatatg aacaaaaaca tatcataaga tagaatagta ataaaaatac
     4981 aaaaaaggga ggaatttgat atgacagaaa caagaaatga aatcaaacta catgttcttt
     5041 ttggtgcttt agcagtagga ttccttatgc tagctctttt ttccttctcg ctacaagtac
     5101 tgccagttgc tgatctagca aaagaatttg gtattccagg cagtgttgcc gctgtggttc
     5161 ttaatgtggt tgaagcgggt ggagctgtca ctacaattgt ctccatttta actgctgtag
     5221 gttcaggcgg tctttctctt attgctgcgg ctggtaaaga gacaattcgt caatacctta
     5281 aaaacgaaat taagaaaaaa ggccgtaaag ccgttatcgc ttggtaattt atttaacgac
     5341 tcaatagaag gagactctgt tctccttcta tttaaatttt tgtgcaggtg agaagatgtt
     5401 atatccttta ttatcactac ttctatccat tagactggag cagcagtatt ctaatatcgc
     5461 tcagtacgtt atacgaaaaa ttccatttct caagtcgttt tcttcaaaac agtacatatt
     5521 tttttcttgt attcttgata tcatattcgg atgcatgatt gtattcgtta tatcttcatt
     5581 tctttactcc cccgtctatc aaatagaatg ggaaagtgct tttgtgatgt ttttatttct
     5641 attttctatc gtcaaaggaa ttgaatctta tagaagaact catcttcttc cttttaaaga
     5701 attgatacag ctagcacctg tttcctctag acaacttttt caaacacttc tgttttcaga
     5761 attgatttgg cttgtgttta cgagtttgag cacttatttg atctattttt tgtttcaata
     5821 tgatattgtt caaacacacg atctggcatt ctggttaaaa catgtcaatg tgttgctgac
     5881 aagtatcttc ctatttatca tcagcaataa gatattcggt gcttatattt ataacatcgt
     5941 cgtaaaaaaa atcggggcca ttcgtgtcct cttttttgca agcatcgctt tgcttttttt
     6001 ctttttcgga agggttctca tattaaacat cattttccct ttttatcaca ccttccagca
     6061 actatttcaa tcgatctcat cgcttgcaga ggattcgttt tggatcactc tttcaaacaa
     6121 gctgatctct ttatatcaac atgatcttca gcaaatgcat catgctttat tttcagatgg
     6181 ctctgttttt ctacaatttc aagccctttt taattcacct attacattga ttgttgtgat
     6241 actaggtagt gcgcttgtca tgagaagtcc tgttcgatgg attccaacgg aaaaagatca
     6301 agaccaaagc tcaaagcatt ttcgggattt attttattgg tactttcaag tactgcataa
     6361 aattcagggt ttgttgttta gacaaaatgt gttgattcaa aaagacatca agctgctgaa
     6421 agaaaaaagg tggctcttat ctaaagaatt ttttaattat atgttcatgt catatgaagc
     6481 cttcttttat attggtgttt ttaccggatt gatctcgatc atcgatcatc aagccttgca
     6541 aattcagctg ctattcacac tcaatattat gatactagca aatcaatctt atgagatgag
     6601 aatgctgaca ccttctattt ttgctttaag tgctgaaaaa aagaacattt ggctttacga
     6661 gctttctcaa atatctcttt tgcaattttt cttatcaaaa atccagttat tttattgttt
     6721 attttccata ccagcactct gtttactatt cattaatcta tctattatga ctgtgtatca
     6781 actgtttcat gttcagatgc tcattcaact ggtggcatta gggattggct ttttcatttt
     6841 tcctttaatc caactgtact tgtttccaat cacaacgaaa ttcaatttta ttcatgagca
     6901 tgaaataggc acaacaaatg aggaactaga gatcatcgat aaaggtcagg catttgccag
     6961 aaactttctt gtactgcctt ttatgtacta tttgattttg acctcttttc tccctatatt
     7021 gcagcaatcc tcagggctcg taaacgtgct gttcgctata tattttgcga tcgtttcagt
     7081 gatttgctgg atattatgcc gcaagaccat ttataaagga attgagtatg ttgaaaaaaa
     7141 taagatattt tctatcggag aatagattga ttctacgtct cggctatctt tacgccggtg
     7201 tatttattgc agctttgctc attggatgcc tccttcctta tgatcagatt ccttatttaa
     7261 aaaaggatga agacatgttt tttctctcta ttttttcaaa caatttacag gttgggcttg
     7321 ccattctagg tatcggggct tttactggcg gcattatgtc tgctggcatt cttttttata
     7381 atggctatat catcggaaaa ctcattcagt ttttgatagc tcagcatgaa gtacagcagt
     7441 tattcactgg cctcatgcca catgcttttg ttgaggttct tggtttgatc ctattttcaa
     7501 tcgtcagtgc ttttccattt atttatcttt accggtttat gaaaggtaag gccattgatg
     7561 taagaaagct gactcggact gtgattcagt taatctttgc cgctgtagtg ctcttgttga
     7621 ttgcctctct tttagaggaa tatgtcagcc atgtacatct atcttagaag aaaggagaat
     7681 gtggttctat ggagctactt ctacgcccta aacaattttt caatcaacat caatcgatca
     7741 aaaccattgt aggtcttgtc ttactatctt tatttgtttc gactgttttt ttaacatttt
     7801 ttatcattga tttgttagta gaggagcctt tatctgctgg aaaacaatta gccagcattg
     7861 tgtttatctt tttactgaca atcccgcttt atttcatatt gaattttctt ggtactgtcg
     7921 ttacttcgat ttatatgtac ttttttcata aaacgtttat tttgcgcaaa atgtattttg
     7981 tcatcttgct ttataatgcg tttcttctat tagtgaatag cgcagcgatc tattgtgtga
     8041 tggtactcga tttagatcat tattttatca tcatccaagc gatttctttt ttgatcaact
     8101 tgtacctttt acgcatccta tatgatggga tcatttatta tgctgaagga tcaaaaaaag
     8161 ccgccctcgc gaccgtcatc ttgtatatgc tggtgaccac tgtttttgtt attggaggat
     8221 ttatcaatgg ctagtttgca agtgtctcag ctatcttttc gttatgaaac aactgaagaa
     8281 agctctcccc tccttgatca agtatccttt catctgaaag aaggtgatcg tgcttgtatt
     8341 atcgggaaaa acggcagcgg taaatcgaca cttttaaaga tcatcgcagg tctgcttcct
     8401 tcagtatccg aaacgatttt actcaacgaa cagcatcatc ctaggtcagc tctttttaaa
     8461 gggttggtcg cgtacattcc agataagcct ttggtttatg atgcgctgac tggtattgag
     8521 catatgactc ttatacagtc actatggaaa atgaatcagt cagaaaaaga ggtatacaaa
     8581 aagacctttc tctcgctttg tgatgcattt gatttaactc atgcacttaa gatgcctgtc
     8641 aaacaatatt cactaggtat gagatataag cttttcttta attgtatggc agccagatca
     8701 ccagaactaa tcattcttga tgaacctttt acatctcttg atgaggcatc tcaaatgcag
     8761 tctatttctt tattaaaaga agaattctct gatcaatgtg ttttatttac aagccatcag
     8821 cgctaccttt attcagaatt aggaaatcgt tttttcgagc ttgatcacgg acaactaaat
     8881 gaaatagagc gttaaacata caaaaggcat cccatcacag gatgcctcac ttctatatac
     8941 cattatctta ccatttacag cgtttgaccg ggcggcagca aggattcttg atatcactgc
     9001 cacagtcata ttcttccaca atatactcat ttcgagtaga ttgcgtcaca gggtagtagt
     9061 tttcaattct tttgatgttt ttattgacgt ttgtgatatg agttggatga atttttctga
     9121 tcgtttgtac atttgttgtc gtgttgacaa tttgacgtgt aggggataca accgtttcaa
     9181 cttctccatg attccccctg cgaggtccaa agaaaaaatt gtctaatcga ttccggctca
     9241 tctcaacacc ccttcaagtt gtctttcact tacactctat cgtatgtaag aggcgcgatt
     9301 agtgattaga tgcttgtcta tttttgataa aatccgcttg tgatctagta gtctctttct
     9361 ttacaacagg acaattttaa catattatac aaatgatctc ttgtgaagga aaggacattc
     9421 attgatgaaa acaagacata agcttttttc atttttcatc ctgctcgtcg tgatcatcac
     9481 ccttcccttg ctgtcgccca tggtttttac aaatgcgact gaaagaggag cgatacggca
     9541 tgccatttat caagaaggct acccttacca aagctatttt gctattttgc aaaaaaagga
     9601 cgatgtagac cctcaatatg gtcagcttta tgatgtgtat tggcaggctt ggaaaagtga
     9661 gacgggaatg acgccttccg tctgttattc aaaaaaggta gaagaccatg aatataaggt
     9721 cagctgcgga actgcaccgt aacatttttc aataacttta aaataagagg tgaacgattt
     9781 gatcaacaca acacaaacca tcgaacgaaa taaactggac attgcacttg aactgacgca
     9841 attgcatttg aatcgatatg aagcaaatca tcctgatcag ctgagtgaaa tttatgccaa
     9901 atattatgca cttcttgaag tgctggacgt atcctcatct gatcaattaa tggatttact
     9961 gccagatgaa ctgaaacaaa tacttgatta aaaaagccat ctatccacac aggatagatg
    10021 gttcagattg ttgaaaaagg gctaaaatga acttgatttt agccctttgt cttcttttca
    10081 gcgtgataga aaacctttga attctaggaa ggacgagtac cggcgcggag cgaatttgac
    10141 attcgtgagc actggcacgc aggactgaca aagaatgcga gggtttgtct acacgctgaa
    10201 accatctatc cacacaggat agatggtttt ctttagacac gtgcagccat atcggtttcg
    10261 atttgttcta agcttcttcc ttttgtttcg actaatacaa agcgcgtgaa caacaggcca
    10321 attaagc
//
