LOCUS       c00004_NZ_JHXY..       16177 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JHXY01000007.1 [Eubacterium] cellulosolvens LD2006
            T358DRAFT_scaffold00004.4_C, whole genome shotgun sequence.
ACCESSION   NZ_JHXY01000007
VERSION     NZ_JHXY01000007
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:39:08
            Original ID  :: NZ_JHXY01000007.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 219697
            Orig. end    :: 235874
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16177
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[229697:230054](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10357)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..16177
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16177
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             618..830
                     /locus_tag="ctg4_190"
                     /transl_table=11
                     /translation="MGIVKQFPYHAKKGWKKSQPFKSYYFFLQFSTMSGNFLAPRLFDA
                     CYSGRQASIWSSYLRTAILGVPVRL"
     CDS             complement(897..2738)
                     /locus_tag="ctg4_191"
                     /transl_table=11
                     /translation="MRKRNGFFRKAAACLVAAVCACSVLASGAMTQTAEAAEDTWRNTY
                     GVTFEKSGTAVTLAQMKDANELKMICDQYTSVTLGNEMKPDYMLGGRARLQTTSEAKEA
                     GYHIPSGYSEDTVPKISFSVMDATMKICYQNNLGLRGHTFVWHSQTPDWFFREGYTANG
                     AYVKPAVMDRRMEMYIKTIMEHAYDSPYGSVLYAWDVVNEYLHAENSSWERVYGNCGHT
                     PEFCKKAFRYAHEVLEEYGLTDEVELYFNDYNTYMEVQDILDVVKYINSDGKVCDGIGM
                     QSHLDTNFPSPDYYIEALTAFLKAGYKVQITELDITCTDETSQTNYTYELLKKICQTQK
                     KYGNITAFVWWGTGDDTSWRSSQKPLMFSKPGQPKSGYAKTLQAYHEVFGAGADLPDPV
                     VVPAEDGFFYDTFEEDCDDWGPFGSPVVDNSKKDSYKGDYALLTSNRDQDWQGCAKTIS
                     TNTYKGGTAYSFGAWVKAVNGYDPQEFSMTLKYVNAQGNTDYAGIGSVKVAAGEWGQIK
                     NESFTIPEGASDMMIYIETPKNTCDFYVDEAFSAPEGEDPTTGSVVEPTKKPTVTPTKK
                     PTVTPTKKPTVKPTQKPQKKRVRYADLDLDGNAHLFP"
     PFAM_domain     complement(1125..1517)
                     /aSDomain="CBM_4_9"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02018.19"
                     /description="Carbohydrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_191_0002"
                     /evalue="3.50E-18"
                     /label="ctg4_191"
                     /locus_tag="ctg4_191"
                     /protein_end="538"
                     /protein_start="407"
                     /score="66.3"
                     /tool="antismash"
                     /translation="FYDTFEEDCDDWGPFGSPVVDNSKKDSYKGDYALLTSNRDQDWQG
                     CAKTISTNTYKGGTAYSFGAWVKAVNGYDPQEFSMTLKYVNAQGNTDYAGIGSVKVAAG
                     EWGQIKNESFTIPEGASDMMIYIETPK"
     PFAM_domain     complement(1590..2597)
                     /aSDomain="Glyco_hydro_10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00331.22"
                     /description="Glycosyl hydrolase family 10"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_191_0001"
                     /evalue="1.30E-64"
                     /label="ctg4_191"
                     /locus_tag="ctg4_191"
                     /protein_end="383"
                     /protein_start="47"
                     /score="218.5"
                     /tool="antismash"
                     /translation="TFEKSGTAVTLAQMKDANELKMICDQYTSVTLGNEMKPDYMLGGR
                     ARLQTTSEAKEAGYHIPSGYSEDTVPKISFSVMDATMKICYQNNLGLRGHTFVWHSQTP
                     DWFFREGYTANGAYVKPAVMDRRMEMYIKTIMEHAYDSPYGSVLYAWDVVNEYLHAENS
                     SWERVYGNCGHTPEFCKKAFRYAHEVLEEYGLTDEVELYFNDYNTYMEVQDILDVVKYI
                     NSDGKVCDGIGMQSHLDTNFPSPDYYIEALTAFLKAGYKVQITELDITCTDETSQTNYT
                     YELLKKICQTQKKYGNITAFVWWGTGDDTSWRSSQKPLMFSKPGQPKSGYAKTLQ"
     CDS             complement(2973..4349)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 147.6; E-value:
                     1e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_192"
                     /transl_table=11
                     /translation="MGHRLRVFAVWGLALLLAAAGIMSIVSCGGPAGIESDNNSSSLRS
                     GSGTTAGANGKDSPDMAVFQYREKEVPLDFSWWGNDVRHIYTLKGIDLFQKQNPEILVN
                     YKFGVWDGYELKNRVRMNSGTDADVMQINFNWLEEYSADGTGYYDLNKLKDQIDLSGYT
                     SEDLKVGQRQDKLNAIPIAYNSTVFFYNKTIYDKYDLPIPETWDDLFAAAARMRDDGIY
                     PLGVVKKHLFQCLMAYYEQTTGRVMFNDTGFRMYKEDVEYVLEFIKKLVDEKVIPLTDD
                     FSAEDFTTGKVAGVGCWNSDASRYCEGLSNRGEDIVIGVNIGSENGSKRYGWYIKPATM
                     YAISAGTEHPKEAAALLNFLVNDKEMILLQGTEKGVPVNRNARTILKEANKLRGFEYKA
                     NVSMMSNRERMGVMIPLMENATVVDTFKKMGDEYIFGRMSLSDCADQILETVHEVVAEG
                     "
     PFAM_domain     complement(3255..4076)
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_192_0003"
                     /evalue="1.70E-24"
                     /label="ctg4_192"
                     /locus_tag="ctg4_192"
                     /protein_end="365"
                     /protein_start="91"
                     /score="87.5"
                     /tool="antismash"
                     /translation="DLFQKQNPEILVNYKFGVWDGYELKNRVRMNSGTDADVMQINFNW
                     LEEYSADGTGYYDLNKLKDQIDLSGYTSEDLKVGQRQDKLNAIPIAYNSTVFFYNKTIY
                     DKYDLPIPETWDDLFAAAARMRDDGIYPLGVVKKHLFQCLMAYYEQTTGRVMFNDTGFR
                     MYKEDVEYVLEFIKKLVDEKVIPLTDDFSAEDFTTGKVAGVGCWNSDASRYCEGLSNRG
                     EDIVIGVNIGSENGSKRYGWYIKPATMYAISAGTEHPKEAAALLNFLVNDKE"
     CDS             complement(4504..5997)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 115; E-value:
                     9.5e-35)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_193"
                     /transl_table=11
                     /translation="MNEKMRKIELTLTFLFSASFLVLALAITFVLTDSSNKVLQKNTAY
                     LMAAESRQLELNINRYFEDVEETAALLFSDPDYYAYDATDPDLDEYTKIKQKEMISSRI
                     FDIGLMQNFSDFGIIYSNDETIGWISQVTNAMFPEGGMYEEFSATIGDEKVGGGWSFGH
                     RGNYDRLYYAKRLNDNAIVVVSFYNRELETVFAYPEQLQSMTICLVDEDDKILYSTDTS
                     KIGNRISASVSQAQSGEENSAVITDSDLITSNSCRNGWRVVCTIPVREIVRENLVNRHR
                     TIAMILVIVLVILVIGLALNYLISRSVKSIVNNLSQRAEHDQMTGLLNKADFQKTVSDV
                     LDRNNQEMAYSFVMLDLDNFKKVNDTLGHAAGDRVIIEAARIIRVCFGDQYIIGRIGGD
                     EFAVFCASAVFSADDLERNVCRVMEGLFTEFDKTFEEERERCMISVSAGCVNTEKGNYR
                     FDVLYKRADQMLYKSKKSGKGKLITCRMSADAASGEGKG"
     aSDomain        complement(4555..5052)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_193_0001"
                     /evalue="1.50E-33"
                     /identifier="TIGR00254"
                     /label="ctg4_193"
                     /locus_tag="ctg4_193"
                     /protein_end="481"
                     /protein_start="315"
                     /score="113.8"
                     /tool="antismash"
                     /translation="SQRAEHDQMTGLLNKADFQKTVSDVLDRNNQEMAYSFVMLDLDNF
                     KKVNDTLGHAAGDRVIIEAARIIRVCFGDQYIIGRIGGDEFAVFCASAVFSADDLERNV
                     CRVMEGLFTEFDKTFEEERERCMISVSAGCVNTEKGNYRFDVLYKRADQMLYKSKKSGK
                     GKL"
     PFAM_domain     complement(4561..5043)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_193_0004"
                     /evalue="2.80E-34"
                     /label="ctg4_193"
                     /locus_tag="ctg4_193"
                     /protein_end="479"
                     /protein_start="318"
                     /score="118.3"
                     /tool="antismash"
                     /translation="AEHDQMTGLLNKADFQKTVSDVLDRNNQEMAYSFVMLDLDNFKKV
                     NDTLGHAAGDRVIIEAARIIRVCFGDQYIIGRIGGDEFAVFCASAVFSADDLERNVCRV
                     MEGLFTEFDKTFEEERERCMISVSAGCVNTEKGNYRFDVLYKRADQMLYKSKKSGKG"
     CDS             complement(6273..7214)
                     /locus_tag="ctg4_194"
                     /transl_table=11
                     /translation="MAITASQVKELREMTGAGMMDCKKALTNTDGDMDKAVEWLRENGM
                     AKAQKKASRIAAEGIVMFTSTEDGKKASIVEVNSETDFAAKNEKFRAYVQQVADQALET
                     SAADIEAFLAETWKYDNAQTVKAALDAQIAVIGENMNIRRFAQVEEAAGFVATYNHADG
                     KIGVLVDVVTDVVNDNVKEMARNVAMQIAAMRPQYTSNKEIPADYIEKEKEILRAAIMN
                     DPKESQKPEKVIEGMVNGRVNKELKEIVLLDQVYVKAEDGKQSVAKYVEQVAKENGANI
                     EIKGFTRFETGEGLEKKNEDFAAEVAAQVASV"
     aSDomain        complement(6285..7214)
                     /aSDomain="TIGR00116"
                     /aSTool="tigrfam"
                     /description="tsf: translation elongation factor Ts"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_194_0002"
                     /evalue="2.60E-92"
                     /identifier="TIGR00116"
                     /label="ctg4_194"
                     /locus_tag="ctg4_194"
                     /protein_end="310"
                     /protein_start="0"
                     /score="307.1"
                     /tool="antismash"
                     /translation="MAITASQVKELREMTGAGMMDCKKALTNTDGDMDKAVEWLRENGM
                     AKAQKKASRIAAEGIVMFTSTEDGKKASIVEVNSETDFAAKNEKFRAYVQQVADQALET
                     SAADIEAFLAETWKYDNAQTVKAALDAQIAVIGENMNIRRFAQVEEAAGFVATYNHADG
                     KIGVLVDVVTDVVNDNVKEMARNVAMQIAAMRPQYTSNKEIPADYIEKEKEILRAAIMN
                     DPKESQKPEKVIEGMVNGRVNKELKEIVLLDQVYVKAEDGKQSVAKYVEQVAKENGANI
                     EIKGFTRFETGEGLEKKNEDFAAEVAAQV"
     PFAM_domain     complement(6336..7001)
                     /aSDomain="EF_TS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00889.21"
                     /description="Elongation factor TS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_194_0005"
                     /evalue="4.50E-67"
                     /label="ctg4_194"
                     /locus_tag="ctg4_194"
                     /protein_end="293"
                     /protein_start="71"
                     /score="225.8"
                     /tool="antismash"
                     /translation="ASIVEVNSETDFAAKNEKFRAYVQQVADQALETSAADIEAFLAET
                     WKYDNAQTVKAALDAQIAVIGENMNIRRFAQVEEAAGFVATYNHADGKIGVLVDVVTDV
                     VNDNVKEMARNVAMQIAAMRPQYTSNKEIPADYIEKEKEILRAAIMNDPKESQKPEKVI
                     EGMVNGRVNKELKEIVLLDQVYVKAEDGKQSVAKYVEQVAKENGANIEIKGFTRFETGE
                     "
     CDS             complement(7482..8222)
                     /locus_tag="ctg4_195"
                     /transl_table=11
                     /translation="MSVISMKQLLEAGVHFGHLTRRWNPKMAPYIYTERNGIYIIDLQK
                     SVGMVDDAYRAIADIVADGGRILFVGTKKQAQDTIKAEAERCGEFFVNERWLGGMLTNF
                     KTVQTRIARLKEIEKMQENGTFDVLPKKEVAGLLKELEKLQKNIGGIKDMKKIPDAIFV
                     VDPKKEKICVQEAHNLGITLIGICDTNCDPEDLDYVIPGNDDAIRAVKLLVSKMADAVI
                     EAKQGQALDAGDEEAAEAAAADAE"
     aSDomain        complement(7545..8216)
                     /aSDomain="TIGR01011"
                     /aSTool="tigrfam"
                     /description="rpsB_bact: ribosomal protein uS2"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_195_0003"
                     /evalue="2.60E-107"
                     /identifier="TIGR01011"
                     /label="ctg4_195"
                     /locus_tag="ctg4_195"
                     /protein_end="226"
                     /protein_start="2"
                     /score="355.2"
                     /tool="antismash"
                     /translation="VISMKQLLEAGVHFGHLTRRWNPKMAPYIYTERNGIYIIDLQKSV
                     GMVDDAYRAIADIVADGGRILFVGTKKQAQDTIKAEAERCGEFFVNERWLGGMLTNFKT
                     VQTRIARLKEIEKMQENGTFDVLPKKEVAGLLKELEKLQKNIGGIKDMKKIPDAIFVVD
                     PKKEKICVQEAHNLGITLIGICDTNCDPEDLDYVIPGNDDAIRAVKLLVSKMADAVIEA
                     KQ"
     PFAM_domain     complement(7551..8198)
                     /aSDomain="Ribosomal_S2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00318.22"
                     /description="Ribosomal protein S2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_195_0006"
                     /evalue="3.20E-96"
                     /label="ctg4_195"
                     /locus_tag="ctg4_195"
                     /protein_end="224"
                     /protein_start="8"
                     /score="320.8"
                     /tool="antismash"
                     /translation="LLEAGVHFGHLTRRWNPKMAPYIYTERNGIYIIDLQKSVGMVDDA
                     YRAIADIVADGGRILFVGTKKQAQDTIKAEAERCGEFFVNERWLGGMLTNFKTVQTRIA
                     RLKEIEKMQENGTFDVLPKKEVAGLLKELEKLQKNIGGIKDMKKIPDAIFVVDPKKEKI
                     CVQEAHNLGITLIGICDTNCDPEDLDYVIPGNDDAIRAVKLLVSKMADAVIEA"
     CDS             complement(8465..9925)
                     /locus_tag="ctg4_196"
                     /transl_table=11
                     /translation="MGRVLENLEPKEVFRFFEELSEIPRPSYHEKAVSDYLVAFAKERG
                     LEYYQDELWNVIMIKEASEGYEDQEPVILQGHMDMVCEKLPGVEKDMEKEGLDLEVDGD
                     FVRAKGTTLGGDDGIAVAYALALLDSDTLKHPRLEFVCTVSEEVGMEGAQVIDCSMLKG
                     RRLLNMDSEEEGTVLASCAGGGCAEVKLAVERKACSWEKVQVHVHGLVGGHSGVEINKG
                     RAASQELMGRILRGAKKATDLRLVAFENGTKDNAISREGRLVLAVEDKAAFLAALERIE
                     TEVRAEYIVVDGDIHFDTEEIALPAGVPDTAAPLSEASTKTVITLLTSLPQGVQRMSDN
                     VEGLVETSLNWGVATLSEKELVMRAAVRSSVKTAKASLCEKISWIAAENGASYRISGEY
                     PAWEWVRESKLREKMSAIYREMFGKELQIEAIHAGVECGLLAEKIEHMDAISMGPDIFD
                     IHTPGERLSISSTKRMYDLIVKIIETKD"
     aSDomain        complement(8474..9904)
                     /aSDomain="TIGR01893"
                     /aSTool="tigrfam"
                     /description="aa-his-dipept: Xaa-His dipeptidase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_196_0004"
                     /evalue="2.20E-157"
                     /identifier="TIGR01893"
                     /label="ctg4_196"
                     /locus_tag="ctg4_196"
                     /protein_end="484"
                     /protein_start="7"
                     /score="522.5"
                     /tool="antismash"
                     /translation="LEPKEVFRFFEELSEIPRPSYHEKAVSDYLVAFAKERGLEYYQDE
                     LWNVIMIKEASEGYEDQEPVILQGHMDMVCEKLPGVEKDMEKEGLDLEVDGDFVRAKGT
                     TLGGDDGIAVAYALALLDSDTLKHPRLEFVCTVSEEVGMEGAQVIDCSMLKGRRLLNMD
                     SEEEGTVLASCAGGGCAEVKLAVERKACSWEKVQVHVHGLVGGHSGVEINKGRAASQEL
                     MGRILRGAKKATDLRLVAFENGTKDNAISREGRLVLAVEDKAAFLAALERIETEVRAEY
                     IVVDGDIHFDTEEIALPAGVPDTAAPLSEASTKTVITLLTSLPQGVQRMSDNVEGLVET
                     SLNWGVATLSEKELVMRAAVRSSVKTAKASLCEKISWIAAENGASYRISGEYPAWEWVR
                     ESKLREKMSAIYREMFGKELQIEAIHAGVECGLLAEKIEHMDAISMGPDIFDIHTPGER
                     LSISSTKRMYDLIVKIIET"
     PFAM_domain     complement(8477..9709)
                     /aSDomain="Peptidase_M20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01546.30"
                     /description="Peptidase family M20/M25/M40"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_196_0007"
                     /evalue="3.50E-14"
                     /label="ctg4_196"
                     /locus_tag="ctg4_196"
                     /protein_end="483"
                     /protein_start="72"
                     /score="53.1"
                     /tool="antismash"
                     /translation="ILQGHMDMVCEKLPGVEKDMEKEGLDLEVDGDFVRAKGTTLGGDD
                     GIAVAYALALLDSDTLKHPRLEFVCTVSEEVGMEGAQVIDCSMLKGRRLLNMDSEEEGT
                     VLASCAGGGCAEVKLAVERKACSWEKVQVHVHGLVGGHSGVEINKGRAASQELMGRILR
                     GAKKATDLRLVAFENGTKDNAISREGRLVLAVEDKAAFLAALERIETEVRAEYIVVDGD
                     IHFDTEEIALPAGVPDTAAPLSEASTKTVITLLTSLPQGVQRMSDNVEGLVETSLNWGV
                     ATLSEKELVMRAAVRSSVKTAKASLCEKISWIAAENGASYRISGEYPAWEWVRESKLRE
                     KMSAIYREMFGKELQIEAIHAGVECGLLAEKIEHMDAISMGPDIFDIHTPGERLSISST
                     KRMYDLIVKIIE"
     CDS             complement(10001..10357)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_197"
                     /sec_met_domain="PF05402 (E-value: 1.1e-13, bitscore: 45.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 8.9e-08, bitscore:
                     25.5, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKKENFLDYIPRANRLYPSVKNSAGHVEIQVEHRGFANFLAQK
                     LFRKPRVSRIELDDFGSFVYLQIDGRKSVYEIAQAVKEKFGEKAEPLYARLSRFIKILH
                     DEHYIVYENKIEKK"
     PFAM_domain     complement(10031..10198)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_197_0008"
                     /evalue="3.40E-11"
                     /label="ctg4_197"
                     /locus_tag="ctg4_197"
                     /protein_end="109"
                     /protein_start="53"
                     /score="43.3"
                     /tool="antismash"
                     /translation="RIELDDFGSFVYLQIDGRKSVYEIAQAVKEKFGEKAEPLYARLSR
                     FIKILHDEHYI"
     CDS             complement(10834..12723)
                     /locus_tag="ctg4_198"
                     /transl_table=11
                     /translation="MSNKEEFKPYVAADQILPEITPVSVIVGVILAIVFGAANAYLGLR
                     VGLTISASIPAAVISKGVIRVILRRDSILENNMVQTIGSAGESLAAGAIFTLPALFMWA
                     EEGATELPSILTIALIALLGGVLGILFMIPLRNALIVEEHGTLPYPEGQACSEVLLAGE
                     EGGAKAGTVFAGLGIAAVYKFIADGLKLFPSEVTYDFKNYPGAGIGMDVLPSLLGVGYI
                     CGPKISSYMMAGGTIAWFVLMPLLYIFGSLNPDALFPAKAAVAELGTGGIWASYIKYIG
                     AGAVACGGVISLIKSLPLIVRTFAGAMKGISKKQSVVTRTTKDLPMNLVLIGIGAIAIA
                     LWLAPDIPVNLLGAIMIIVFGFFFVTVSARMVGIVGSSNNPVSGMTIATMLVATIVLKA
                     TGNIGTKGMIAAISIGSVICISAAIAGDTSQDLKTGYVVGATPWKQQLGEIFGVAVSAV
                     AIGFVLYLLNAAWGYGSAELPAPQAGMMKMIVEGVMDGNLPWPLVFVGVFLGIVVEILQ
                     IPVLPFAVGLYLPIYLSTPMMVGGLVRLWVDRNKKISEEERKGRVENGTLFCSGLIAGE
                     GLVGVLLAIFAVVELDLDISKTIDLGQIGGCVCFAVLVALLCVFMNKKSKKTA"
     PFAM_domain     complement(10963..12669)
                     /aSDomain="OPT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03169.17"
                     /description="OPT oligopeptide transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_198_0009"
                     /evalue="3.00E-100"
                     /label="ctg4_198"
                     /locus_tag="ctg4_198"
                     /protein_end="587"
                     /protein_start="18"
                     /score="336.8"
                     /tool="antismash"
                     /translation="EITPVSVIVGVILAIVFGAANAYLGLRVGLTISASIPAAVISKGV
                     IRVILRRDSILENNMVQTIGSAGESLAAGAIFTLPALFMWAEEGATELPSILTIALIAL
                     LGGVLGILFMIPLRNALIVEEHGTLPYPEGQACSEVLLAGEEGGAKAGTVFAGLGIAAV
                     YKFIADGLKLFPSEVTYDFKNYPGAGIGMDVLPSLLGVGYICGPKISSYMMAGGTIAWF
                     VLMPLLYIFGSLNPDALFPAKAAVAELGTGGIWASYIKYIGAGAVACGGVISLIKSLPL
                     IVRTFAGAMKGISKKQSVVTRTTKDLPMNLVLIGIGAIAIALWLAPDIPVNLLGAIMII
                     VFGFFFVTVSARMVGIVGSSNNPVSGMTIATMLVATIVLKATGNIGTKGMIAAISIGSV
                     ICISAAIAGDTSQDLKTGYVVGATPWKQQLGEIFGVAVSAVAIGFVLYLLNAAWGYGSA
                     ELPAPQAGMMKMIVEGVMDGNLPWPLVFVGVFLGIVVEILQIPVLPFAVGLYLPIYLST
                     PMMVGGLVRLWVDRNKKISEEERKGRVENGTLFCSGLIAGEGLVGVLLAIFA"
     aSDomain        complement(10966..12669)
                     /aSDomain="TIGR00733"
                     /aSTool="tigrfam"
                     /description="TIGR00733: oligopeptide transporter, OPT
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_198_0005"
                     /evalue="1.80E-124"
                     /identifier="TIGR00733"
                     /label="ctg4_198"
                     /locus_tag="ctg4_198"
                     /protein_end="586"
                     /protein_start="18"
                     /score="414.3"
                     /tool="antismash"
                     /translation="EITPVSVIVGVILAIVFGAANAYLGLRVGLTISASIPAAVISKGV
                     IRVILRRDSILENNMVQTIGSAGESLAAGAIFTLPALFMWAEEGATELPSILTIALIAL
                     LGGVLGILFMIPLRNALIVEEHGTLPYPEGQACSEVLLAGEEGGAKAGTVFAGLGIAAV
                     YKFIADGLKLFPSEVTYDFKNYPGAGIGMDVLPSLLGVGYICGPKISSYMMAGGTIAWF
                     VLMPLLYIFGSLNPDALFPAKAAVAELGTGGIWASYIKYIGAGAVACGGVISLIKSLPL
                     IVRTFAGAMKGISKKQSVVTRTTKDLPMNLVLIGIGAIAIALWLAPDIPVNLLGAIMII
                     VFGFFFVTVSARMVGIVGSSNNPVSGMTIATMLVATIVLKATGNIGTKGMIAAISIGSV
                     ICISAAIAGDTSQDLKTGYVVGATPWKQQLGEIFGVAVSAVAIGFVLYLLNAAWGYGSA
                     ELPAPQAGMMKMIVEGVMDGNLPWPLVFVGVFLGIVVEILQIPVLPFAVGLYLPIYLST
                     PMMVGGLVRLWVDRNKKISEEERKGRVENGTLFCSGLIAGEGLVGVLLAIF"
     CDS             12860..13318
                     /locus_tag="ctg4_199"
                     /transl_table=11
                     /translation="MWHTRQISPLSESKRYADYAYLYSYFYLQTVVFRVLAKIFTAEWF
                     EQSICSPCVKPKTFYNFAVLSASQRNIYAHARENQKNYIRFRFLIYIFNVEFAVLLFIF
                     IYSFKKRFKAASALNTCILFTLAVCIMSTLCNSVTNHPTAPKDTVSYK"
     CDS             complement(13389..14171)
                     /locus_tag="ctg4_200"
                     /transl_table=11
                     /translation="MLKAAISKENTKREAFEALLEKREELIAAIGTEEKPGPDAKAVDD
                     AKNAVATAKTAYDDAKTAYEKVLDDLTAAKAAYDKAVKNTTVVYRLYNKVTREHLYSTS
                     ALEKKILVEGGWIDENYAWIAPKKSDDTIPVYRLYNKNTTDHHYTTDENEVKELVKRGD
                     WTNDGPVFYAVKEGPVDVLRICNPNLPIGMHLFTTDKNEYETLYIKGWGVKEGNAFDVI
                     ATHDAYIEKTTNDPEKLDKELKAADKEVNATENTEGKG"
     PFAM_domain     complement(13512..13631)
                     /aSDomain="DUF5648"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18885.2"
                     /description="Repeat of unknown function (DUF5648)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_200_0012"
                     /evalue="9.20E-09"
                     /label="ctg4_200"
                     /locus_tag="ctg4_200"
                     /protein_end="220"
                     /protein_start="180"
                     /score="35.3"
                     /tool="antismash"
                     /translation="VLRICNPNLPIGMHLFTTDKNEYETLYIKGWGVKEGNAFD"
     PFAM_domain     complement(13653..13769)
                     /aSDomain="DUF5648"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18885.2"
                     /description="Repeat of unknown function (DUF5648)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_200_0011"
                     /evalue="5.00E-16"
                     /label="ctg4_200"
                     /locus_tag="ctg4_200"
                     /protein_end="173"
                     /protein_start="134"
                     /score="58.6"
                     /tool="antismash"
                     /translation="VYRLYNKNTTDHHYTTDENEVKELVKRGDWTNDGPVFYA"
     PFAM_domain     complement(13803..13910)
                     /aSDomain="DUF5648"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18885.2"
                     /description="Repeat of unknown function (DUF5648)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_200_0010"
                     /evalue="3.50E-12"
                     /label="ctg4_200"
                     /locus_tag="ctg4_200"
                     /protein_end="123"
                     /protein_start="87"
                     /score="46.3"
                     /tool="antismash"
                     /translation="VYRLYNKVTREHLYSTSALEKKILVEGGWIDENYAW"
     CDS             14318..14584
                     /locus_tag="ctg4_201"
                     /transl_table=11
                     /translation="VTVPVTAQLPVQLTVPVTAQLPVQLTVPVTAQLPVQLTVPVTAQL
                     PVQLTVQVTVPVTAQLPVQLTVPVTAQLPVQLTVQVTVPDGKA"
ORIGIN
        1 tcatccttct gcatgtactc catcgcggag agcagtcgct catcattcag cgtcttcgcg
       61 atgcgaatgc gttccttatc ctccgcctgc tccatgaggg aagcaagttc atcctcttcc
      121 agcagtgcgc aaagaccggc cgtttccgta tcatcgagtt cgccgaccat ctccgcaaag
      181 tcgatgggtt gaaatagccc gataaatgcg gaaagcttct cgtgatcccc ctcttcgatc
      241 agggcacgga gctctttcag atccttattc ttaaatttct ccatgatatt tctccttcaa
      301 aatgtgtttt cagctgcagt cgcagtagtt tcattgaaga agacagacgt ggttaagcta
      361 tgtatttttc gacaggaaat atactaaaaa taaatgccgg aggtgccccc tatgccgggc
      421 gaagagctcc ggattcgtct tccggatcct gttcgtatga aattacaact tcgaccgtga
      481 ctgtctccgt ccatagtggt acctccttct cggcatattt ctcaggtaat tttcatttgc
      541 aagctttttg tgcggcggga gaatcgcgaa gcgatcttcc catctgcgag ctgcgcatct
      601 aagcggagcg ttgtggtatg gggattgtga agcaatttcc ataccacgca aagaaaggtt
      661 ggaaaaaatc ccaacctttc aaatcatact atttttttct tcagttttca acgatgtccg
      721 ggaactttct agcgccgagg ctttttgatg cgtgctattc gggcaggcag gcaagtattt
      781 ggtcgagtta tttaagaacg gctatactag gtgttccggt ccggttatag ccggcattac
      841 accgcatcat gcacgtataa tgcagactct gttacaccag tgccctctca cgatatttac
      901 ggaaagaggt gagcatttcc atcgagatca agatctgcgt agcgaacacg ttttttctgc
      961 ggtttctgcg taggtttcac cgtgggtttc ttcgtcggtg tgacggtggg tttctttgta
     1021 ggagtcacgg tcggtttctt cgtcggctca accacggaac cggttgtagg atcttctccc
     1081 tccggtgcac tgaaggcctc gtccacgtag aaatcacacg tatttttcgg tgtctcaatg
     1141 taaatcatca tgtccgaagc gccctccgga atggtgaagg actcgttctt gatctgtccc
     1201 cactctccgg cagcaacttt cacgcttccg attcccgcat agtccgtatt tccctgggca
     1261 tttacgtatt tcagcgtcat ggagaactcc tgcggatcat atccgttcac tgcctttacc
     1321 caggcgccga aactgtaggc cgttccgccc ttatacgtat tggtactgat tgtttttgcg
     1381 caaccctgcc agtcctgatc acggttgctg gtcagaaggg cgtagtcacc tttgtaggaa
     1441 tctttcttcg agttgtctac gaccggcgag ccaaacgggc cccagtcatc gcagtcttcc
     1501 tcaaaggtat catagaagaa gccatcctct gcgggaacaa cgaccggatc cggaagatcc
     1561 gctcctgcgc cgaacacctc gtgataagcc tgaagtgtct tcgcataacc ggatttcggc
     1621 tgtcccggct tgctgaacat cagcggtttc tgactgcttc tccaggaagt gtcatcgccg
     1681 gttccccacc atacgaaggc agtgatgttt ccgtattttt tctgtgtctg acagatcttc
     1741 ttgaggagct cataggtgta gttcgtctga gaagtctcat cggtacaggt gatatcaagc
     1801 tctgtgatct gcaccttgta tccggccttc agaaaggcag taagtgcctc aatgtagtag
     1861 tccggagacg ggaagtttgt atccagatga gactgcatgc cgataccgtc gcagactttt
     1921 ccgtcagagt tgatgtattt cacaacgtcc agaatatcct gcacttccat gtaggtattg
     1981 tagtcattga aatagagttc aacctcgtcg gtcagtccgt actcctccag tacctcgtgc
     2041 gcataccgga aggctttttt acaaaactcc ggcgtgtggc cacagtttcc gtatactctc
     2101 tcccagctgg agttctctgc gtgcagatac tcattgacaa catcccacgc gtacagcacg
     2161 cttccgtaag ggctgtcgta ggcgtgttcc atgatcgtct tgatgtacat ctccatacgt
     2221 ctgtccatca ccgccggttt gacataggca ccgtttgcgg tgtacccctc acggaaaaac
     2281 cagtccggcg tctgcgaatg ccacacaaag gtgtgtccgc gaagccccag attgttctgg
     2341 tagcagatct tcatcgtcgc gtccatgacg ctgaacgaaa tcttcggaac tgtatcctcg
     2401 gaatagccgg acggaatatg gtagccggcc tcctttgcct cggaggttgt ctgaagtctc
     2461 gcccgtccgc cgagcatgta atccggcttc atctcgtttc cgagcgtcac actggtgtac
     2521 tgatcgcaga tcatcttcag ctcattcgca tccttcatct gcgccagagt caccgcggta
     2581 cccgatttct caaaggtcac tccatacgtg ttgcgccatg tatcctctgc cgcttctgcc
     2641 gtctgtgtca tggcgccgga agccagcaca ctgcacgcgc acactgcggc aacgagacag
     2701 gctgcggcct tcctgaaaaa cccgtttctc tttctcataa gcaatccccc tgattgtatg
     2761 aataatagta aaaatatgag ttctgtgtat tattttttca cacaattcag tttttttcta
     2821 cacaaatctg tgcacaatta ttcggcatta ttacaattct ttcgacacag aacatcgaaa
     2881 ctttcgaaac acatgaagac ggacgggcca ttcgacccgt ccgtctttat gcgtagttat
     2941 ttacggtcaa agcacaaagc acactccctc tttcaccctt ctgccacaac ctcatgcacg
     3001 gtctcgagga tctgatccgc gcagtcagac aggctcatgc ggccgaagat gtactcgtcg
     3061 cccatcttct tgaaggtgtc gaccaccgtc gcattttcca tcagcggaat catgacgccc
     3121 atccgctccc ggttgctcat catgctgaca ttcgctttgt actcaaagcc cctcagctta
     3181 ttcgcctcct tcaggattgt ccgggcattc cggtttacag gaacgccctt ctcggttccc
     3241 tgaaggagaa tcatctcctt gtcattgacc agaaaattca gtagcgccgc agcttctttc
     3301 ggatgctccg tccctgcgct gatggcatac atggtggcag gtttgatgta ccagccatat
     3361 cgcttcgagc cgttttccga accgatattg acgccgatca cgatatcctc tccccggttg
     3421 ctcaatccct cgcaatatct gctggcgtcg ctgttccagc aaccgacccc ggccaccttg
     3481 ccggtggtaa agtcctcggc gctaaaatca tctgtgagag gaatcacttt ttcatccaca
     3541 agttttttga taaactccag aacgtactcc acatcctcct tgtacatccg gaatccggta
     3601 tcattgaaca tgaccctgcc cgtggtctgc tcataataag ccatcagaca ctggaagaga
     3661 tgtttcttca caacccccaa cggatagatc ccgtcatccc tcatacgagc cgctgccgca
     3721 aagagatcat cccaggtctc cggtatagga agatcgtatt tatcatagat ggtcttgtta
     3781 tagaaaaaga cagtggagtt gtaggcaatg ggaatggcat tcagcttatc ctgacgctga
     3841 ccgaccttaa gatcctccga cgtgtaaccc gagagatcaa tctggtcttt gagtttgttc
     3901 agatcatagt accccgtgcc atccgcagaa tactcctcca gccagttgaa gttaatctgc
     3961 atcacatcgg cgtcggtccc ggagttcata cgcacccggt ttttcagctc atagccgtcc
     4021 cacacgccga atttgtaatt gaccagaatt tcaggatttt gcttctggaa cagatcgatc
     4081 cccttcagcg tataaatatg gcggacatca ttgccccacc aggaaaaatc caggggcacc
     4141 tctttttcac gatattgaaa gacagccata tccgggctgt ccttcccgtt cgccccggct
     4201 gtcgttccac ttcccgaacg cagagacgag gaattattgt cactctcaat ccctgcaggt
     4261 cccccgcaag acacaatact catgattccg gccgccgcca acagcagcgc cagtccccaa
     4321 accgcgaaaa cccgcaatct gtgtcccatg tacgctctcc ttatttctgt catttcttat
     4381 accgtacgat gtctgttccg ccagcccacg caggctctcc cggcagttta catctcagaa
     4441 gagaatctcc cgcatccctt ctgtgccaat atgcactgcg cagatacgag gatatccgat
     4501 ccctcagccc ttcccctcac cagatgccgc gtccgcagac atcctgcagg taataagctt
     4561 tccttttccg gatttctttg atttgtacag catctgatcc gcgcgtttat acagaacgtc
     4621 gaaacgatag ttgcctttct ccgtatttac acagccggcg ctgacagaga tcatacatcg
     4681 ttcccgctcc tcttcgaaag tcttgtcaaa ttccgtgaac aagccctcca tcaccctgca
     4741 gacattcctc tcgaggtcat ctgcagaaaa aacagctgat gcgcagaaga cagcaaactc
     4801 atcaccgccg atccggccga tgatatactg atcgccaaag cagacacgga taatccgggc
     4861 cgcttctatg atcacacggt ctcccgctgc gtgtcccagt gtgtcattga ctttcttgaa
     4921 gttgtccaaa tccagcatca cgaaactgta ggccatctcc tgattgttcc tgtcaaggac
     4981 gtccgacacc gtcttctgga agtctgcttt attcaaaagc cccgtcatct gatcatgctc
     5041 tgcccgctgg ctcagattgt tcacgatgct cttcacagac cgtgagatca gataattgag
     5101 agcgagtccg atcacaagga tcacaaggac aatcaccaga atcatggcaa tggtgcgatg
     5161 ccggttaacc agattctccc gcacaatctc ccgcaccgga atcgtacaga caactcgcca
     5221 tccgtttctg caggaatttg atgtgatgag atcactgtcg gtgatgaccg ccgagttctc
     5281 ctccccgctc tgcgcctgcg ataccgacgc cgatatcctg tttccgatct ttgacgtatc
     5341 cgtggaataa agaatcttgt catcctcgtc aacaaggcag atggtcatcg actgaagctg
     5401 ctccggatac gcaaagaccg tctccagctc ccggttgtaa aaggagacga cgacgatggc
     5461 attgtcattc agacgcttcg catagtacaa ccggtcgtaa tttcccctgt ggccgaaaga
     5521 ccagccgccc ccgacctttt catccccgat ggtcgcagag aattcctcat acattccacc
     5581 ttccgggaac atggcattcg taacctgtga aatccacccg atcgtctcat cgttggaata
     5641 aataataccg aaatcagaaa aattctgcat caggccgatg tcaaagatcc ttgatgagat
     5701 catctccttc tgtttgatct tcgtgtattc atccagatcc ggatccgtgg cgtcatacgc
     5761 gtagtagtcc ggatctgaaa acagcagtgc cgctgtctct tcgacatcct caaaatatct
     5821 gttgatgttc agttcgagct gtctgctctc cgcagccatc agatacgcag tattcttctg
     5881 aagtaccttg ttggaactgt ccgtcaatac aaatgtgatt gccagcgcaa gcacaagaaa
     5941 agacgccgaa aacaggaacg taagcgtgag ctcgatcttc cgcatcttct cattcatttc
     6001 cggatttcct ctaaatctag tcttgtcatt tttgtaactc atatctaaat aatatcacaa
     6061 tatttgtgac tgcactacga tatttcgctt cgtcttattt gtctcatggg aaattcggag
     6121 gaatttccta tgagaggaca aagtccgcaa gcgaaacatt ttatctctta gggaatgcga
     6181 gaatttttct gtggagaaaa aaagacacga tcacaatgac cgtgcctttt attgtttata
     6241 taatgatcat tctctgcgaa tgtacaagtc gattatacgc ttgcaacctg agcagcaacc
     6301 tcagcagcga agtcctcgtt cttcttctca agaccctcac ctgtctcgaa acgtgtgaag
     6361 cccttgatct cgatgttagc gccgttctct tttgcaacct gctctacgta cttggcaacg
     6421 gactgttttc cgtcctcagc ttttacgtat acctggtcaa gaagaacgat ctctttgagc
     6481 tctttgttta cacggccgtt aaccattccc tcgataacct tctccggttt ctgggactct
     6541 ttcgggtcgt tcatgatagc tgccctgaga atctctttct ctttctcgat gtaatcagcc
     6601 gggatctcct tgttgcttgt gtactgaggt ctcatagctg cgatctgcat agctacattt
     6661 ctggccatct ctttaacgtt gtcgtttact acatctgtaa caacgtctac aagaacaccg
     6721 atcttaccat ctgcatggtt gtaagtagca acgaagcctg ctgcctcctc aacctgagcg
     6781 aaacgacgga tgttcatgtt ctcaccgata acagcgatct gagcatcaag tgcagcctta
     6841 actgtctgtg cgttgtcata tttccatgtc tcagcaagga aagcctcaat atcagctgcg
     6901 gatgtctcaa gagcctgatc agcaacctgc tgaacgtatg cgcggaactt ctcgttcttt
     6961 gcagcgaagt ctgtctcaga gttaacctct acgatagaag ctttctttcc atcctctgtg
     7021 gatgtgaaca ttacgatacc ctctgcagcg atacggcttg ctttcttctg agccttagcc
     7081 ataccgttct cacggagcca ctctactgcc ttgtccatat caccgtctgt atttgtaagg
     7141 gctttcttgc agtccatcat tccggcgccg gtcatctctc ttaactcttt tacctgagaa
     7201 gctgtaattg ccatttctct atcctcctga atatatttga tctctaaaaa aaatgtttcc
     7261 ctgcggcaat ttacgccgtg cccggacacg ctttttcgtc ccggacggtt gtttttcccg
     7321 cagaatctgt ctctgcacag aaagcacgga cttcctgtcg cagaagaaaa gacgcgagtt
     7381 tacgcgcagc gactttacgt gcgaagcaca tcagtggagc agcgaaaatc tcgcgtctta
     7441 aggaatctat tcgattataa atctattaac cgtccggtga attactcagc gtcagcagct
     7501 gctgcctctg cagcctcctc atcgccggca tccagagcct gtccctgttt tgcctcgata
     7561 acagcgtctg ccatcttgga aacaagaagt tttacggcgc ggattgcgtc atcgttaccc
     7621 gggattacgt agtcaaggtc ctccggatcg cagtttgtat cgcagatacc gatcagagtg
     7681 attccaaggt tgtgagcctc ctgtacgcag atcttctctt tcttcggatc tacaacgaag
     7741 attgcatccg ggatcttctt catatctttg ataccgccga tgttcttctg aagtttctca
     7801 agctctttga gaaggcccgc aacctctttc ttaggaagaa cgtcgaaggt tccgttctcc
     7861 tgcatcttct cgatctcttt gagacgggcg atacgagtct gaacagtctt gaagtttgta
     7921 agcataccgc cgagccatct ctcgtttacg aagaactctc cgcaacgctc agcctcagct
     7981 ttgattgtat cctgtgcctg tttctttgta ccaacgaaga ggattcttcc tccgtcagct
     8041 acgatatcag caattgcacg gtaagcgtcg tcaaccattc ctaccgattt ctgaaggtcg
     8101 atgatgtaga ttccgttacg ctctgtgtag atgtaaggag ccatcttagg gttccatctt
     8161 cttgtgaggt gaccgaaatg tacaccggct tcgagtaact gcttcattga aattacgctc
     8221 atgttctttt ctcctttggt ttttaacttc cgcatggttc aacttcgcag ggaacctgaa
     8281 aaaacgggca ccaccctgaa aatttccatg cgtgtttatt taaacagctt gattattgta
     8341 ccacagataa aaatgtgaga caagcatttt ttcgcttatt cccagcgttt tttgcccgtc
     8401 tcacattcgt ttttcttcag aatgatcacc tgttgccacg aagttctgat gttttgtccc
     8461 tacatcagtc cttcgtctca atgatcttca caatcagatc gtacatgcgc tttgtggagg
     8521 agatggaaag cctctcgccc ggcgtgtgga tatcgaagat atccggtccc atggagatgg
     8581 cgtccatgtg ctcgatcttc tctgccagaa gaccgcactc gacgccggcg tggatcgcct
     8641 caatctgaag ctctttgccg aacatctctc tgtagatcgc ggacatcttc tcgcggagct
     8701 tcgattctct cacccactcc caggccgggt actcgccgga gatcctgtag gacgcaccgt
     8761 tctccgccgc gatccaggaa atcttttcgc agaggcttgc ctttgcagtc ttcacggaac
     8821 tgcgaaccgc cgcccgcatc acaagttctt tttcggacag ggtcgcaacg ccccagttca
     8881 gggacgtctc caccagcccc tccacgttgt cgctcattct ctgcacgccc tgcggaaggg
     8941 aggtgagaag agtaatcacg gtcttcgtcg acgcctcgga aagcggagca gcagtatccg
     9001 gaacgcctgc cggaagagcg atctcctccg tgtcaaagtg aatatcgccg tccacaacaa
     9061 tgtactccgc gcgaacctcc gtctcgatcc gctccagcgc ggcgaggaag gccgccttat
     9121 cctcgacagc aaggacaagt cttccctctc tggaaatcgc gttgtccttg gttccgttct
     9181 caaaggcaac gagacgcaga tccgtcgcct tttttgcgcc gcggaggatt cttcccatca
     9241 gctcctggga agccgcgcgc cccttgttga tctcgacgcc ggagtgtcca cccacaagac
     9301 cgtgcacatg cacctgaact ttctcccagg agcaggcctt acgctcaacg gcgagtttca
     9361 cctcggcaca gccgccgccc gcgcagctgg caaggaccgt tccctcctcc tcggagtcca
     9421 tgttcagaag acggcggccc ttcagcatgg agcagtcgat cacctgcgca ccctccatgc
     9481 cgacctcctc cgagacggtg cagacgaact cgagtctcgg gtgcttcagc gtgtcggaat
     9541 ccagaagggc aagggcgtag gcaaccgcga tgccgtcatc cccgccgagg gtcgttccct
     9601 tcgcgcggac gaaatcaccg tcaacctcga gatccagccc ctctttctcc atatcttttt
     9661 ccacgcccgg aagcttctcg cagaccatat ccatatgccc ctgcagaatc accggctcct
     9721 gatcctcata gccctcggag gcctctttga tcatgatcac attccagagc tcatcctgat
     9781 aatactccag tcccctctcc ttcgcgaagg caaccagata gtcgctgact gctttctcgt
     9841 ggtaagacgg ccgcgggatc tccgacagct cctcaaaaaa gcggaaaact tccttcggtt
     9901 ccagattttc caatactcta cccatcgttc tatactctct ttctattctt tctgttcttt
     9961 ctaaatcttt atgcttcccg atccggcgac cggtcactcg tcacttcttt tcaatcttgt
    10021 tctcgtagac aatgtagtgc tcgtcgtgca gaattttgat gaagcgggac agtctcgcgt
    10081 agagcggctc cgccttctct ccgaacttct ctttgaccgc ctgggcgatc tcgtagacgc
    10141 ttttcctgcc gtcgatctgc agataaacaa agctgccgaa gtcatccagc tcaatccggc
    10201 tgaccctcgg cttcctgaac aatttctgcg caaggaagtt ggcgaagcct ctgtgctcca
    10261 cctgaatctc cacatggccg gcgctgttct ttacggacgg atacagccgg ttcgctctcg
    10321 ggatataatc gagaaaattc tctttctttc gggacataca tttctctcct gtctcttagc
    10381 ttgacttacg atattgatct acggatccac ataccggctg ccgcgcacac tccttatgca
    10441 cacgccggct ctgcctgtac acaacgaagc cgcccgcaca caggcccata tcccctgtgc
    10501 accgattata gctctgcgtg ttcagaattt caaattccgg atatctgttc tttccaaccc
    10561 acggcaaaaa cagagaaaag ttttctgccg caaattcgaa acagcacaca ttcgataaat
    10621 atacgtgtag gggaacccca aaggagtttc cataacaaat aatgctcgcg caacctcctt
    10681 cctccaagag cggatgcgaa acatctactc atcacgcggg tatacatccc aaaaccagga
    10741 tgaggccgcc gcacagcatt tcattcctat gctttccgtg cgacagcctc acacaaatcc
    10801 ggcgcgcctc aaaacgggac gcgcccggac ctcttatgca gtctttttgc tctttttgtt
    10861 catgaagaca cagagaaggg caaccagtac cgcgaagcat acgcagccgc cgatctgtcc
    10921 gagatcaatc gtcttggaga tatcaagatc aagttcgact acggcaaaga ttgcgagaag
    10981 aactccgaca agtccctctc cggcgatcag accggagcag aacagcgtac cgttctcaac
    11041 tcttcccttg cgctcctcct cggagatctt cttattcctg tctacccaga gacgaacaag
    11101 tccgccgacc atcatcggtg tggacaggta gatcggaagg tagagaccaa ccgcgaacgg
    11161 aagaaccgga atctgaagga tctcaacaac aatgccgagg aagacgccta cgaatacgag
    11221 cggccatgga aggtttccgt ccataactcc ctctacgatc atcttcatca taccagcctg
    11281 cggagccggg agctctgcgg atccgtagcc ccacgccgcg ttgagcaggt agagaacaaa
    11341 accgatggca acggcagata cagcaacgcc gaagatctca ccgagctgct gtttccacgg
    11401 cgtggcgccg acaacatagc cggtcttcag atcctgtgaa gtatcgccgg caatcgccgc
    11461 ggagatacag atgacagaac cgatggagat cgctgcgatc atacccttcg ttccgatatt
    11521 tccggtagcc ttgagcacga tggtcgcaac aagcatggtc gcgattgtca taccggaaac
    11581 cgggttgttg gaacttccta cgatacctac cattcgggca gatacggtaa caaagaagaa
    11641 accgaagacg atgatcatga tggcgccgag aaggttgacc gggatgtccg gagcaagcca
    11701 gagcgcgatg gcgatggcgc cgatgccgat cagaacgagg ttcatcggaa gatcctttgt
    11761 tgttcttgtg acaacgctct gcttcttcga gatgcccttc attgcgccgg caaaggtgcg
    11821 gacgatgagc ggaagggatt tgatcagaga gatcacacca ccgcaggcaa cggcgccggc
    11881 accgatgtac ttgatgtagg acgcccagat tccgccggtt ccaagctcag caacagcggc
    11941 cttcgccggg aaaagagcat ccgggttcag acttccgaag atgtacagaa gcggcatcag
    12001 aacgaaccac gcgatcgtac cgccggccat catgtaggac gaaatcttcg gtccgcagat
    12061 gtaacccacg ccgagaaggg aaggaaggac atccattccg ataccggcgc ccggatagtt
    12121 cttgaaatca taggtaactt ctgacgggaa cagtttcagt ccgtccgcga taaatttgta
    12181 gacagccgcg ataccaagac ccgcgaagac agttcctgct ttcgctccac cctcttctcc
    12241 ggcgagaaga acttcggaac aagcctggcc ttccggataa ggaagggtac cgtgctcctc
    12301 aacgatcagg gcgtttctca gcggaatcat gaaaagaatt ccgagtacgc cgccgagcag
    12361 agcgatcaga gcgatcgtaa ggatcgacgg aagctccgta gctccttctt ctgcccacat
    12421 aaaaagcgcc ggaagtgtga aaatagctcc cgccgccagg gactcaccgg ccgaaccgat
    12481 ggtctgcacc atgttattct caaggatgga atctctgcga agaatcacgc ggatcacacc
    12541 cttggagata acagctgccg ggattgaagc ggaaatggta agtccgactc tcaatccgag
    12601 ataagcgttc gctgcgccga acacgatcgc cagaattaca ccaacgatga cagagaccgg
    12661 tgtaatttcc ggaaggatct gatcagcagc aacgtaaggc ttaaactcct ctttgttact
    12721 cataacaaac tcctcctgca aatatgcaat ttttgcccga taaaaaatac atcagcatcc
    12781 tggtcatcag aaaaaagctt cctatccatt ctctacgtct ttatttttta taaagcaatt
    12841 cgaaagatat tataaaaaaa tgtggcatac tcgtcaaatt tcacccttgt ccgaaagcaa
    12901 aagatatgcg gattatgcat atttatacag ttatttttat ttgcaaacag tcgttttccg
    12961 cgtactcgcc aaaatattta cggcagaatg gtttgaacag tccatttgtt cgccctgcgt
    13021 caagcctaaa accttttata atttcgcggt attatctgcg tcccaacgca acatctacgc
    13081 acatgcacga gaaaaccaga aaaattacat ccgctttcga tttctgatat atattttcaa
    13141 tgtcgaattt gctgttttat tattcatatt tatatacagt ttcaaaaagc gtttcaaagc
    13201 agcatccgcg ctcaatacat gtatactatt cactttggcg gtttgcatta tgtctactct
    13261 ttgcaattct gtcacgaacc atccaacagc tcccaaagac accgtaagct ataaataacc
    13321 tccctgccat ccgaatccgg atgacaggga ggtaactgcg ctacttaaac gtcagtaacg
    13381 acggatgctt atcctttgcc ttcggtgttt tcagttgcat ttacttcctt atctgctgct
    13441 tttaattcct tatccagttt ctccgggtcg tttgtggtct tttcgatgta agcgtcatga
    13501 gtcgcaatca catcaaacgc attaccctct tttacgcccc atcctttgat gtagagggtc
    13561 tcgtactcgt tcttatctgt cgtgaagaga tgcataccaa tcggaagatt cggattgcag
    13621 attctgagta catcaaccgg tccctctttc actgcgtaga ataccggtcc gtcattcgtc
    13681 caatctcctc tctttacaag ctccttcacc tcattttcat ctgtggtgta gtgatgatcg
    13741 gtcgtattct tgttgtacag acggtataca ggaattgtat catcgctctt cttcggtgcg
    13801 atccatgcat aattctcatc gatccatccg ccctccacga ggatcttctt ctcaagagcg
    13861 cttgtagaat acagatgctc acgtgtcacc ttattgtaaa gtctgtaaac aaccgtggtg
    13921 ttctttacag ctttatcgta agctgctttg gctgccgtta aatcatcaag aactttctca
    13981 taggcagttt tggcatcatc ataggctgtc ttagcagttg ctaccgcatt ctttgcatca
    14041 tcaactgcct ttgcatctgg tccaggcttc tcttctgtcc caatagccgc tatcagttct
    14101 tcacgttttt cgagaagagc ctcaaaagcc tcacgtttag tattctcttt gctgattgca
    14161 gccttcaaca tttcatccgt ctcatattta gcggcgtttt caagagcctc ttcatataca
    14221 gccttagctt ccgcaaccgg atcttcagta gtcgcaggcg caccaccttg ttccggacta
    14281 gcttccggct cagcttccgg ttcagttgac ggttcaggtg acggttccgg tgacggctca
    14341 gcttccggtt cagttgacgg ttccggtgac ggctcagctt ccggttcagt tgacggttcc
    14401 ggtgacggct cagcttccgg ttcagttgac ggttccggtg acggctcagc ttccggttca
    14461 gttgacggtt caggtgacgg ttccggtgac ggctcagctt ccggttcagt tgacggttcc
    14521 ggtgacggct cagcttccgg ttcagttgac ggttcaggtg acggttcctg atggaaaggc
    14581 ataagctgac cttctttcag aatacctaaa tcacgcaaac cttcatctct ggtatttata
    14641 taattttcca ttgatgaaaa aaccgcattt attgcattaa acgcatttac ttctgatgct
    14701 tttggttcat gcgtcgttgg atcaagcagt ttatcaatta ctcggctacg tctctcgtca
    14761 gcatcattct cagcctctct aagcgcctca taagcctcag caatttttgt atcattaagc
    14821 tctttcaatt cagtctcatc tgctttaagc ttatcttctg cagctttctg cttgtcttct
    14881 gctgttttat acgcagtttt cttctctgta tatgccgctt ttgtatctgt tacagcttta
    14941 tctgcgtctt ttactttttt cgcaagctcg tcgacagtct tcttgtcttc tgtctttttc
    15001 tcactgccgg ctgccagcgc cgttgtgtca ccagcatatg ctactcctgc caatcctgta
    15061 gcggttactg ataccactga agccaaaaca agtgccttta ccattttgtt tttcattctg
    15121 tacgctcctt tattgtgtat tgaccagtaa atagatacca cttgcatgaa aaaaagacgc
    15181 cacaaacact gatgtctgtg acgcagagga gttgcagctg gctgacattt gacagtccct
    15241 atagctttgc gtcgcagact ttcgtctgtt ttgccatgca ttatttaatt tgttcataat
    15301 cattatataa tagctgaaaa tatattttta tccgcaaata tcacaaatat aaatatcttt
    15361 ttatatgcaa tgtgatacat attgaatagt tttcatctta ttatgattga tattccatcg
    15421 tatctgctat gcttcgaaat ccatgagtca taactgtcac acagatcgct gtgactcaga
    15481 ttgttttctc ttctgtattg cgctcatggt tacagatctg ttgttttttg atcaggcatg
    15541 gcagacatca aaacaatcac gattgatcta gtgcgcaatt gtcatccaaa tttaggaata
    15601 ccagagccag aataacgaac aataagtaag tccgcggcaa aggccgcgga cttacttatt
    15661 gtttgatcct atttactatt ccattttttg tgttatagaa atttcggagg aagttcttat
    15721 aacataaaaa acggtttcaa gtactgtgta ctcgaaacca ttcttttaag aagaggcgtg
    15781 agccggattt gaaccggcgg atactggtgt tgcagaccat tgccttacca cttggctatc
    15841 acgccataac atatatgatt atatcaaact ttgctgataa atcaagacga ttttgaaaca
    15901 attttctcaa taatcagaac tttgtttcaa aatgtgactg caggaagatc ctgcagtcac
    15961 tcgaagctcc ccgaccagga ctcgaaccag ggacatcatg attaacagtc atgcgctcta
    16021 ccgactgagc tatcgaggaa tacttctgaa ggtacctaca taccttcaaa actgaacaca
    16081 cgaactacca aagtctgcat ttattttaca gaatcagtca ttcaaaagtg cttcgcactt
    16141 tttttgatga ttctctttac agaatcggtc attcgaa
//
