LOCUS       NC_014933.1            20381 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_014933.1 Bacteroides helcogenes P 36-108, complete sequence.
ACCESSION   NC_014933
VERSION     NC_014933.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:07:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1942200
            Orig. end    :: 1962581
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20381
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1952200:1952581](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10381
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20381
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20381
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2205..3245
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1543"
                     /sec_met_domain="PF04055 (E-value: 5.2e-16, bitscore: 57.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKQPLLGLTLSELQNVVKNLGMPGFAAKQIASWLYDKKVLSIDE
                     MSNLSLRHRELLKELYEVGAEIPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDDDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTANLTANQIINQISSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALEVMTASYGYSWSPKRITLSSVGLRKGLQRFIEESDCHLAISLHTPVPLQRRE
                     LMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLLYAKELLKLLRGLDCRI
                     NLIRFHAIPEVDLEGADMETMTALRDYLTAHGLFTTIRSSRGEDIFAACGMLSTAKQED
                     DKQELI"
     aSDomain        2211..3227
                     /aSDomain="TIGR00048"
                     /aSTool="tigrfam"
                     /description="rRNA_mod_RlmN: 23S rRNA
                     (adenine(2503)-C(2))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1543_0001"
                     /evalue="1.20E-106"
                     /identifier="TIGR00048"
                     /label="ctg1_1543"
                     /locus_tag="ctg1_1543"
                     /protein_end="341"
                     /protein_start="2"
                     /score="354.6"
                     /tool="antismash"
                     /translation="KQPLLGLTLSELQNVVKNLGMPGFAAKQIASWLYDKKVLSIDEMS
                     NLSLRHRELLKELYEVGAEIPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDDDRATLCV
                     SSQVGCKMNCKFCMTGKQGFTANLTANQIINQISSLPERDKLTNVVMMGMGEPLDNLDE
                     VLKALEVMTASYGYSWSPKRITLSSVGLRKGLQRFIEESDCHLAISLHTPVPLQRRELM
                     PAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLLYAKELLKLLRGLDCRINL
                     IRFHAIPEVDLEGADMETMTALRDYLTAHGLFTTIRSSRGEDIFAACGMLSTAKQEDD"
     PFAM_domain     2523..2993
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1543_0011"
                     /evalue="6.20E-15"
                     /label="ctg1_1543"
                     /locus_tag="ctg1_1543"
                     /protein_end="263"
                     /protein_start="106"
                     /score="56.1"
                     /tool="antismash"
                     /translation="SSQVGCKMNCKFCMTGKQGFTANLTANQIINQISSLPERDKLTNV
                     VMMGMGEPLDNLDEVLKALEVMTASYGYSWSPKRITLSSVGLRKGLQRFIEESDCHLAI
                     SLHTPVPLQRRELMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDS"
     CDS             3314..4372
                     /locus_tag="ctg1_1544"
                     /transl_table=11
                     /translation="MKKHLFYLGMTLVLALFAGCSNGKKGVFTPTSSGRAYEILVVVTP
                     GVWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDINKDLY
                     TQPKFKYAKDVYAAPQSILTIQAPDEASFEKFVEENTQVVIDFFTHAEMNRQIAVLKDK
                     HSDYVSTKVKGLFGCDVWIPGELTATKEGKNFFWAGTNSATGDQNFVIYSYPYTDRNTF
                     TKEYFIHKRDSVMKENIPGAREGMYMMTDSLMTDVHPISVQGDYALEARGLWRVKGDFM
                     GGPFVSHTRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPDNKQESAEIPV
                     NVASKDSINNKK"
     PFAM_domain     3407..4288
                     /aSDomain="DUF4837"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16125.7"
                     /description="Domain of unknown function (DUF4837)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1544_0012"
                     /evalue="4.10E-108"
                     /label="ctg1_1544"
                     /locus_tag="ctg1_1544"
                     /protein_end="325"
                     /protein_start="31"
                     /score="361.0"
                     /tool="antismash"
                     /translation="SSGRAYEILVVVTPGVWERPAGRALFDVLDSDVPGLPQSERSFRI
                     MYTAPSNYDATLKLIRNIIIVDINKDLYTQPKFKYAKDVYAAPQSILTIQAPDEASFEK
                     FVEENTQVVIDFFTHAEMNRQIAVLKDKHSDYVSTKVKGLFGCDVWIPGELTATKEGKN
                     FFWAGTNSATGDQNFVIYSYPYTDRNTFTKEYFIHKRDSVMKENIPGAREGMYMMTDSL
                     MTDVHPISVQGDYALEARGLWRVKGDFMGGPFVSHTRLDKANQRIIVSEIFIYSPDKMK
                     RNLVRQMEASLYT"
     CDS             4374..5471
                     /locus_tag="ctg1_1545"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFSDPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPTNFSIVNSASEAAYNRLSVVNCTDDEVKVEFSKPDPEAGKAAFGALE
                     KAIEEYKEGLIDVIVTAPINKHTIQSDEFSFPGHTEYIEQKLGNGEKALMILMKDDFRV
                     ALVTGHIPVSQIASTVTKELIQEKLSIFNRSLKQDFGISAPRIAVLSLNPHAGDEGLLG
                     MEEQEIIIPALNEMAAKGMLCYGPYAADGFMGSGNFTHFDGVLAMYHDQGLSPFKALAM
                     DEGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAVYVAIDVYRNRQRDKAARTN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     aSDomain        4395..5354
                     /aSDomain="TIGR00557"
                     /aSTool="tigrfam"
                     /description="pdxA: 4-hydroxythreonine-4-phosphate
                     dehydrogenase PdxA"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1545_0002"
                     /evalue="1.40E-110"
                     /identifier="TIGR00557"
                     /label="ctg1_1545"
                     /locus_tag="ctg1_1545"
                     /protein_end="327"
                     /protein_start="7"
                     /score="367.6"
                     /tool="antismash"
                     /translation="VGITQGDINGVGYEVILKTFSDPVMLELCTPIIYGSPKVAAYHRK
                     SLDLPTNFSIVNSASEAAYNRLSVVNCTDDEVKVEFSKPDPEAGKAAFGALEKAIEEYK
                     EGLIDVIVTAPINKHTIQSDEFSFPGHTEYIEQKLGNGEKALMILMKDDFRVALVTGHI
                     PVSQIASTVTKELIQEKLSIFNRSLKQDFGISAPRIAVLSLNPHAGDEGLLGMEEQEII
                     IPALNEMAAKGMLCYGPYAADGFMGSGNFTHFDGVLAMYHDQGLSPFKALAMDEGVNYT
                     AGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAVYVAIDV"
     PFAM_domain     4476..5345
                     /aSDomain="PdxA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04166.14"
                     /description="Pyridoxal phosphate biosynthetic protein
                     PdxA"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1545_0013"
                     /evalue="9.00E-104"
                     /label="ctg1_1545"
                     /locus_tag="ctg1_1545"
                     /protein_end="324"
                     /protein_start="34"
                     /score="346.9"
                     /tool="antismash"
                     /translation="LCTPIIYGSPKVAAYHRKSLDLPTNFSIVNSASEAAYNRLSVVNC
                     TDDEVKVEFSKPDPEAGKAAFGALEKAIEEYKEGLIDVIVTAPINKHTIQSDEFSFPGH
                     TEYIEQKLGNGEKALMILMKDDFRVALVTGHIPVSQIASTVTKELIQEKLSIFNRSLKQ
                     DFGISAPRIAVLSLNPHAGDEGLLGMEEQEIIIPALNEMAAKGMLCYGPYAADGFMGSG
                     NFTHFDGVLAMYHDQGLSPFKALAMDEGVNYTAGLPVVRTSPAHGTAYDIAGKGLASED
                     SFRQAVYVA"
     CDS             5473..6729
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 382.3; E-value:
                     5.7e-116)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1546"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALLRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQIPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDAKQI
                     LLSYSWPGNVRQLKNITEQISIIETNREINSTILKGYLPEQSNMQRLPALFGVKDTKGF
                     ESEREILYQVLFDMRQDVTELKKLVHEIMTEQGRGVVSAPAVTPSTYYAPNAPAVTPPV
                     TSGMPTIIHPAVKPTSAVDDDIQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQ
                     DLNISERTLYRKIKEYGLD"
     PFAM_domain     5515..6018
                     /aSDomain="Sigma54_activat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00158.28"
                     /description="Sigma-54 interaction domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1546_0014"
                     /evalue="2.50E-65"
                     /label="ctg1_1546"
                     /locus_tag="ctg1_1546"
                     /protein_end="182"
                     /protein_start="14"
                     /score="219.4"
                     /tool="antismash"
                     /translation="IIGNNEALLRAIDIAIQVAPTDLSVLITGESGVGKESFPQIIHQY
                     SRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFGEANGGTIFLDEVGE
                     LPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAIADGRFREDLYYRLN
                     TVPIQ"
     PFAM_domain     6592..6717
                     /aSDomain="HTH_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02954.21"
                     /description="Bacterial regulatory protein, Fis family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1546_0015"
                     /evalue="1.40E-14"
                     /label="ctg1_1546"
                     /locus_tag="ctg1_1546"
                     /protein_end="415"
                     /protein_start="373"
                     /score="53.6"
                     /tool="antismash"
                     /translation="SLDEVEKEMIRKALEKHHGKRKSAAQDLNISERTLYRKIKEY"
     CDS             6716..7243
                     /locus_tag="ctg1_1547"
                     /transl_table=11
                     /translation="MDWIKKTTPVVFLVILGFVVCSCRISMGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKLKDMFIQQTRLRLVDSGGDLEISGEITGYNQYNEAVDA
                     SGYSSKVKLTLTVKVTYVNNADHKDDFTDQQFSAFQTYDSSQLLTAVQDNLITLMVKDI
                     TEQIFNATVANW"
     PFAM_domain     6833..7225
                     /aSDomain="LptE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04390.14"
                     /description="Lipopolysaccharide-assembly"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1547_0016"
                     /evalue="3.00E-16"
                     /label="ctg1_1547"
                     /locus_tag="ctg1_1547"
                     /protein_end="170"
                     /protein_start="39"
                     /score="60.1"
                     /tool="antismash"
                     /translation="VKTISIADFQNRAEYVYAPLATEFNQKLKDMFIQQTRLRLVDSGG
                     DLEISGEITGYNQYNEAVDASGYSSKVKLTLTVKVTYVNNADHKDDFTDQQFSAFQTYD
                     SSQLLTAVQDNLITLMVKDITEQIFNA"
     CDS             7249..8094
                     /locus_tag="ctg1_1548"
                     /transl_table=11
                     /translation="MTSAHLQQWIQHPETLDRDSLYELRTLVTRYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRMLFYLIEGDRYTLKSQKSSLLFSRVIEDEPSVDRTL
                     SLIDAFLATVPEEHPRNMELDYAMDYTSYLMQEEETDGQLEVCAEAVEIPKLRGHELID
                     GFLLKSEAADMRLLEMKPDIEEEHPAGTNVGEVRDEETEASEMKEAMEDETPAESHVVG
                     DSDDSCFTETLAKIYIKQHRYDKALEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK
                     "
     CDS             8099..8461
                     /locus_tag="ctg1_1549"
                     /transl_table=11
                     /translation="MYLLLIILMVIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIASAYTIPSSSAKSGDVIMEQAQQEEKTNPYNMPVGTAA
                     PQTEAPAAPTEQPVGE"
     aSDomain        8102..8311
                     /aSDomain="TIGR00810"
                     /aSTool="tigrfam"
                     /description="secG: preprotein translocase, SecG subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1549_0003"
                     /evalue="9.70E-21"
                     /identifier="TIGR00810"
                     /label="ctg1_1549"
                     /locus_tag="ctg1_1549"
                     /protein_end="71"
                     /protein_start="1"
                     /score="71.6"
                     /tool="antismash"
                     /translation="YLLLIILMVIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKT
                     TDFLEKATWTLAAVMVVFSIASAYT"
     PFAM_domain     8108..8308
                     /aSDomain="SecG"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03840.16"
                     /description="Preprotein translocase SecG subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1549_0017"
                     /evalue="3.20E-19"
                     /label="ctg1_1549"
                     /locus_tag="ctg1_1549"
                     /protein_end="70"
                     /protein_start="3"
                     /score="69.0"
                     /tool="antismash"
                     /translation="LLIILMVIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKTTD
                     FLEKATWTLAAVMVVFSIASAY"
     CDS             8613..10004
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 88.1; E-value: 7.7e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1550"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMAAYYVNDVVAPLKTMLE
                     TDLAWTSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTALADADATIFGIKEILGYKTGVFIAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPMARALGISSPVLLGLILLLGGMVAFFVFSVMDKKL
                     DKQMEAAAIAAGTENEEEKFSFKDVRNILGNPGFWLIALLCVLFYSCVFPFQKFASELM
                     ILKYGIGENVAGAFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PFIQFWLVAIVLMIVLGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGKVLDVYCITGKNPDGTSIYDYTIPMCIFTGIACLSLIIALLLKKADKKYGYKLEE
                     PNIKE"
     PFAM_domain     8676..9794
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1550_0018"
                     /evalue="8.90E-24"
                     /label="ctg1_1550"
                     /locus_tag="ctg1_1550"
                     /protein_end="394"
                     /protein_start="21"
                     /score="84.2"
                     /tool="antismash"
                     /translation="IVAFTMMAAYYVNDVVAPLKTMLETDLAWTSTDFGFFTGGYSFLN
                     VFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYYAMTALADADATIFGIKEILGY
                     KTGVFIAFAGYSIFGVGAEVAGITVSKIIAKWFKGKELATAMGVQVALARIGSQAGYAV
                     AIPMARALGISSPVLLGLILLLGGMVAFFVFSVMDKKLDKQMEAAAIAAGTENEEEKFS
                     FKDVRNILGNPGFWLIALLCVLFYSCVFPFQKFASELMILKYGIGENVAGAFAGLPALG
                     ALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAIPFIQFWLVAIVLMIVLGIAFS
                     LVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIG"
     CDS             10001..10381
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1551"
                     /sec_met_domain="PF05402 (E-value: 5.3e-15, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 5.3e-08, bitscore:
                     30.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNLRTDVYNMETLEGKVSLLDAVPVRCGHIGTEWEGECVVLSYPR
                     FKYEWMRRFLLPKGMSPDIYVKLEEHGTAVWNLIDGHRTVRQIISLLAGHFEGEDNYES
                     RVTTYVMQLRRDGFIRLTVRKG"
     PFAM_domain     10109..10357
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1551_0019"
                     /evalue="3.00E-15"
                     /label="ctg1_1551"
                     /locus_tag="ctg1_1551"
                     /protein_end="119"
                     /protein_start="36"
                     /score="56.3"
                     /tool="antismash"
                     /translation="ECVVLSYPRFKYEWMRRFLLPKGMSPDIYVKLEEHGTAVWNLIDG
                     HRTVRQIISLLAGHFEGEDNYESRVTTYVMQLRRDGFI"
     CDS             complement(10470..11522)
                     /locus_tag="ctg1_1552"
                     /transl_table=11
                     /translation="MKKKLLWISALLIATGVHAQTEVTTGVMRGKEYGVTYLLPKTEIE
                     IVLQITKHTYTPGEFCKYADRYLRLGNVSAEPEAYWTLDKIQPRIAGIPDKDNVYFVKL
                     KDKTVAPLMELTEDGIVRSINMPLSGQKPDKAVKTIGSPENSIDPRSFLTEEILMSNSS
                     AKMAELVAKEIYNIRESKNALLRGEADNMPKDGTQLKLMLDNLNLQELAMTEMFSGTVK
                     SESGTFTIRITPKEMKDEIAFRFSKKLGIVANNDFAGEPYYISITDLKTPDTSGTEESK
                     KKTEGIAYNVPGRAKVTLVQKNKKLFEEEFPITQFGIIEYLAPVLFNKNSTIKVLFDTA
                     TGGLIKVDRE"
     PFAM_domain     complement(10491..11426)
                     /aSDomain="DUF4831"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16115.7"
                     /description="Domain of unknown function (DUF4831)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1552_0020"
                     /evalue="3.60E-123"
                     /label="ctg1_1552"
                     /locus_tag="ctg1_1552"
                     /protein_end="344"
                     /protein_start="32"
                     /score="410.8"
                     /tool="antismash"
                     /translation="YGVTYLLPKTEIEIVLQITKHTYTPGEFCKYADRYLRLGNVSAEP
                     EAYWTLDKIQPRIAGIPDKDNVYFVKLKDKTVAPLMELTEDGIVRSINMPLSGQKPDKA
                     VKTIGSPENSIDPRSFLTEEILMSNSSAKMAELVAKEIYNIRESKNALLRGEADNMPKD
                     GTQLKLMLDNLNLQELAMTEMFSGTVKSESGTFTIRITPKEMKDEIAFRFSKKLGIVAN
                     NDFAGEPYYISITDLKTPDTSGTEESKKKTEGIAYNVPGRAKVTLVQKNKKLFEEEFPI
                     TQFGIIEYLAPVLFNKNSTIKVLFDTATGGL"
     CDS             complement(11638..12726)
                     /locus_tag="ctg1_1553"
                     /transl_table=11
                     /translation="MLGLSVAACTPRKAVNKTSDELAMLVGTYTNGTSKGIYTFRFNQE
                     TGTAIPLSTMELPNPSYLIPSEDGKFVYAVSEMNDSTAALSSFAFDKSTGILRLLNTEP
                     TLGADPCYVATNGKEALTANYSGGSMSVFPLRKDGTLGPVDTLFIGSATGTDTIRQITA
                     HIHCTVFSPDGKYIFATDFSADRILRFVLHPKDIIPHLSAETTDIAPGSGPRHLTFSPN
                     GKYAYLITELSGKVIAFSYDNGKLEQIQTITADTIAARGSADIHLSPDGKYLYASNRLR
                     EDGIAIFAVSPDNGTLAKAGYQPTGIHPRHFNITPNGKYLLAACRDSNTIQIYERNATT
                     GLLKDTHRNITVDKPVCIQFVQ"
     PFAM_domain     complement(11647..12657)
                     /aSDomain="Lactonase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10282.11"
                     /description="Lactonase, 7-bladed beta-propeller"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1553_0021"
                     /evalue="1.20E-105"
                     /label="ctg1_1553"
                     /locus_tag="ctg1_1553"
                     /protein_end="360"
                     /protein_start="23"
                     /score="353.7"
                     /tool="antismash"
                     /translation="MLVGTYTNGTSKGIYTFRFNQETGTAIPLSTMELPNPSYLIPSED
                     GKFVYAVSEMNDSTAALSSFAFDKSTGILRLLNTEPTLGADPCYVATNGKEALTANYSG
                     GSMSVFPLRKDGTLGPVDTLFIGSATGTDTIRQITAHIHCTVFSPDGKYIFATDFSADR
                     ILRFVLHPKDIIPHLSAETTDIAPGSGPRHLTFSPNGKYAYLITELSGKVIAFSYDNGK
                     LEQIQTITADTIAARGSADIHLSPDGKYLYASNRLREDGIAIFAVSPDNGTLAKAGYQP
                     TGIHPRHFNITPNGKYLLAACRDSNTIQIYERNATTGLLKDTHRNITVDKPVCIQF"
     CDS             complement(12937..15771)
                     /locus_tag="ctg1_1554"
                     /transl_table=11
                     /translation="MRKLIVAVLLLGNGALLSAQKTMKIPAIYKPVKSEMYRKGWIDFN
                     KNGIMDIYEDPTAAIDARIEDLLKQMSLEEKTCQMVTLYGYKRVLKDDLPTPEWKQMLW
                     KDGIGAIDEHLNGFRQWGLPPSDNENVWPASRHAWALNEVQRFFVEETRLGIPVDFTNE
                     GIRGVESYKATNFPTQLGLGHTWNRELIHKIGFITGREARMLGYTNVYAPILDVGRDQR
                     WGRYEEVYGESPYLVAELGIEMVRGMQYNHQVAATGKHFAAYSNNKGAREGMSRVDPQI
                     SPREVENIHIYPFRRVIREAGLLGVMSSYNDYDGIPIQGSHYWLTTRLRGEIGFRGYVV
                     SDSDAVEYLYTKHGTAKDMKEAIRQSVEAGLNIRCTFRSPDSFVLPLRELVKEGGLSEE
                     IINDRVRDILRVKFLTGLFDTPYQSDLAGADREVEKEENGSIALQASRESIVLLKNENN
                     MLPLDLSTVKRIAVCGPNADEKNYALTHYGPLAVEVITVLKGIQDKVSGKAEVLYTKGC
                     DLVDANWPESEIINHPLTADEQAEINKAAENARQSDVAVVVLGGGQRTCGENKSRSSLD
                     LPGRQLQLLQAIQATGKPVILVLINGRPLSVNWADKYVPAILEAWYPGAKGGIALADVL
                     FGDYNPGGKLTVTFPKTVGQIPFNFPYKPASQIDGGKNPGPEGNMSRINGALYPFGYGL
                     SYTTFEYSDLEITPKVITPNEEATVRLKVTNTGKRAGDEVVQLYIRDVVSSVITYEKNL
                     AGFERVHLEPGETKEVVFTLGRKHLELLDANMQWVVEPGDFTIMAAASSEDIRLNGLLT
                     VEDYQMRAKAIETSKPAERVSASANRENACNATDGRIDTAWQGNKGDYITFALGNGIQT
                     NKVSIAFMRDNNLPADFDIQLSGGGGQFLTVYSGVVSEYGKMISYSFKGTTASDLRIVL
                     NDDHVGIAEVKLTE"
     PFAM_domain     complement(13366..13575)
                     /aSDomain="Fn3-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14310.8"
                     /description="Fibronectin type III-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1554_0024"
                     /evalue="7.70E-22"
                     /label="ctg1_1554"
                     /locus_tag="ctg1_1554"
                     /protein_end="802"
                     /protein_start="732"
                     /score="77.3"
                     /tool="antismash"
                     /translation="EVVQLYIRDVVSSVITYEKNLAGFERVHLEPGETKEVVFTLGRKH
                     LELLDANMQWVVEPGDFTIMAAASS"
     PFAM_domain     complement(13684..14424)
                     /aSDomain="Glyco_hydro_3_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01915.24"
                     /description="Glycosyl hydrolase family 3 C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1554_0023"
                     /evalue="7.80E-59"
                     /label="ctg1_1554"
                     /locus_tag="ctg1_1554"
                     /protein_end="696"
                     /protein_start="449"
                     /score="199.2"
                     /tool="antismash"
                     /translation="IVLLKNENNMLPLDLSTVKRIAVCGPNADEKNYALTHYGPLAVEV
                     ITVLKGIQDKVSGKAEVLYTKGCDLVDANWPESEIINHPLTADEQAEINKAAENARQSD
                     VAVVVLGGGQRTCGENKSRSSLDLPGRQLQLLQAIQATGKPVILVLINGRPLSVNWADK
                     YVPAILEAWYPGAKGGIALADVLFGDYNPGGKLTVTFPKTVGQIPFNFPYKPASQIDGG
                     KNPGPEGNMSRINGALYPFGYGLSY"
     PFAM_domain     complement(14539..15555)
                     /aSDomain="Glyco_hydro_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00933.23"
                     /description="Glycosyl hydrolase family 3 N terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1554_0022"
                     /evalue="7.10E-61"
                     /label="ctg1_1554"
                     /locus_tag="ctg1_1554"
                     /protein_end="411"
                     /protein_start="72"
                     /score="206.5"
                     /tool="antismash"
                     /translation="LEEKTCQMVTLYGYKRVLKDDLPTPEWKQMLWKDGIGAIDEHLNG
                     FRQWGLPPSDNENVWPASRHAWALNEVQRFFVEETRLGIPVDFTNEGIRGVESYKATNF
                     PTQLGLGHTWNRELIHKIGFITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGESPY
                     LVAELGIEMVRGMQYNHQVAATGKHFAAYSNNKGAREGMSRVDPQISPREVENIHIYPF
                     RRVIREAGLLGVMSSYNDYDGIPIQGSHYWLTTRLRGEIGFRGYVVSDSDAVEYLYTKH
                     GTAKDMKEAIRQSVEAGLNIRCTFRSPDSFVLPLRELVKEGGLSEEIINDRVRDILRV"
     CDS             complement(16528..16956)
                     /locus_tag="ctg1_1555"
                     /transl_table=11
                     /translation="MEENLYLDLLAKRGIQPTAIRILVLQAMLKTRRSVSLLDLENILD
                     TVDKSTIFRTITLFLSHHLIHSIDDGTGSFKYAVCSASCSCEVNDLHTHFHCERCNKTF
                     CFKNIPTPVVNLPEGFTLNSINYVLKGLCPECAAKVLK"
     PFAM_domain     complement(16633..16917)
                     /aSDomain="FUR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01475.21"
                     /description="Ferric uptake regulator family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1555_0025"
                     /evalue="1.50E-06"
                     /label="ctg1_1555"
                     /locus_tag="ctg1_1555"
                     /protein_end="108"
                     /protein_start="13"
                     /score="28.4"
                     /tool="antismash"
                     /translation="GIQPTAIRILVLQAMLKTRRSVSLLDLENILDTVDKSTIFRTITL
                     FLSHHLIHSIDDGTGSFKYAVCSASCSCEVNDLHTHFHCERCNKTFCFKN"
     CDS             complement(16966..18924)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 418.1; E-value:
                     1.2e-126)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1556"
                     /transl_table=11
                     /translation="MGHHNCKCCAHDSAQSQKVPVNSNALKDYRKIILSALLLFGGIIM
                     DMMDITFFREKYVALIWYISAYLPVGLPVMKEAWKSIVEKDVFSEFTLMTIATLGAFYI
                     REYPEGVAVMLFYSLGELFQGKAVDRAKRNISTLLDVRPETATVIKENEPVVETPQKVQ
                     VGEIIEVKAGERVPLDGVMQSEAAAFNTSALTGESRPRSIRRGEEVLAGMIVTDKVTRI
                     QVTRPFENSALSRILELVQNASERKAPAELFIRKFARIYTPIVTVLAVLTVLLPFIYSL
                     INVQFTFVFDDWLYKALVFLVISCPCALVVSIPLGYFGGIGAASRLGVLFKGGNYLDAI
                     TQVNTVVFDKTGTLTKGTFNVQSCETQPGISEEKLIQLAASVERNSTHPIAKAIVSYAR
                     ERNIALEPTTEVTEIAGHGLVTTIGGKRILAGNIRLLSKYQINYPEELSLISDTIVACA
                     MGTEYTGYLLLADTLKEDAVQAVNELKALNINNIQILSGDKQAIVTNFAQKLGVREAYG
                     DLLPDGKVKHIEELRQHAGNRIAFVGDGINDAPVLALSNIGIAMGGLGSDAAIETADVV
                     IQTDQPSKVATAIRVAKHTRRIIWQNISLAFGVKLLVLVLGAGGLATLWEAVFADVGVA
                     LIAIVNAIRIQKFIKIE"
     aSDomain        complement(16987..18651)
                     /aSDomain="TIGR01512"
                     /aSTool="tigrfam"
                     /description="ATPase-IB2_Cd: cadmium-translocating P-type
                     ATPase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1556_0005"
                     /evalue="3.10E-139"
                     /identifier="TIGR01512"
                     /label="ctg1_1556"
                     /locus_tag="ctg1_1556"
                     /protein_end="646"
                     /protein_start="91"
                     /score="462.8"
                     /tool="antismash"
                     /translation="TLMTIATLGAFYIREYPEGVAVMLFYSLGELFQGKAVDRAKRNIS
                     TLLDVRPETATVIKENEPVVETPQKVQVGEIIEVKAGERVPLDGVMQSEAAAFNTSALT
                     GESRPRSIRRGEEVLAGMIVTDKVTRIQVTRPFENSALSRILELVQNASERKAPAELFI
                     RKFARIYTPIVTVLAVLTVLLPFIYSLINVQFTFVFDDWLYKALVFLVISCPCALVVSI
                     PLGYFGGIGAASRLGVLFKGGNYLDAITQVNTVVFDKTGTLTKGTFNVQSCETQPGISE
                     EKLIQLAASVERNSTHPIAKAIVSYARERNIALEPTTEVTEIAGHGLVTTIGGKRILAG
                     NIRLLSKYQINYPEELSLISDTIVACAMGTEYTGYLLLADTLKEDAVQAVNELKALNIN
                     NIQILSGDKQAIVTNFAQKLGVREAYGDLLPDGKVKHIEELRQHAGNRIAFVGDGINDA
                     PVLALSNIGIAMGGLGSDAAIETADVVIQTDQPSKVATAIRVAKHTRRIIWQNISLAFG
                     VKLLVLVLGAGGLATLWEAVFADVGVALIAIVNAIRIQ"
     aSDomain        complement(16993..18651)
                     /aSDomain="TIGR01525"
                     /aSTool="tigrfam"
                     /description="ATPase-IB_hvy: heavy metal translocating
                     P-type ATPase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1556_0004"
                     /evalue="1.40E-159"
                     /identifier="TIGR01525"
                     /label="ctg1_1556"
                     /locus_tag="ctg1_1556"
                     /protein_end="644"
                     /protein_start="91"
                     /score="530.5"
                     /tool="antismash"
                     /translation="TLMTIATLGAFYIREYPEGVAVMLFYSLGELFQGKAVDRAKRNIS
                     TLLDVRPETATVIKENEPVVETPQKVQVGEIIEVKAGERVPLDGVMQSEAAAFNTSALT
                     GESRPRSIRRGEEVLAGMIVTDKVTRIQVTRPFENSALSRILELVQNASERKAPAELFI
                     RKFARIYTPIVTVLAVLTVLLPFIYSLINVQFTFVFDDWLYKALVFLVISCPCALVVSI
                     PLGYFGGIGAASRLGVLFKGGNYLDAITQVNTVVFDKTGTLTKGTFNVQSCETQPGISE
                     EKLIQLAASVERNSTHPIAKAIVSYARERNIALEPTTEVTEIAGHGLVTTIGGKRILAG
                     NIRLLSKYQINYPEELSLISDTIVACAMGTEYTGYLLLADTLKEDAVQAVNELKALNIN
                     NIQILSGDKQAIVTNFAQKLGVREAYGDLLPDGKVKHIEELRQHAGNRIAFVGDGINDA
                     PVLALSNIGIAMGGLGSDAAIETADVVIQTDQPSKVATAIRVAKHTRRIIWQNISLAFG
                     VKLLVLVLGAGGLATLWEAVFADVGVALIAIVNAIR"
     aSDomain        complement(17059..18585)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1556_0006"
                     /evalue="8.80E-65"
                     /identifier="TIGR01494"
                     /label="ctg1_1556"
                     /locus_tag="ctg1_1556"
                     /protein_end="622"
                     /protein_start="113"
                     /score="216.9"
                     /tool="antismash"
                     /translation="MLFYSLGELFQGKAVDRAKRNISTLLDVRPETATVIKENEPVVET
                     PQKVQVGEIIEVKAGERVPLDGVMQSEAAAFNTSALTGESRPRSIRRGEEVLAGMIVTD
                     KVTRIQVTRPFENSALSRILELVQNASERKAPAELFIRKFARIYTPIVTVLAVLTVLLP
                     FIYSLINVQFTFVFDDWLYKALVFLVISCPCALVVSIPLGYFGGIGAASRLGVLFKGGN
                     YLDAITQVNTVVFDKTGTLTKGTFNVQSCETQPGISEEKLIQLAASVERNSTHPIAKAI
                     VSYARERNIALEPTTEVTEIAGHGLVTTIGGKRILAGNIRLLSKYQINYPEELSLISDT
                     IVACAMGTEYTGYLLLADTLKEDAVQAVNELKALNINNIQILSGDKQAIVTNFAQKLGV
                     REAYGDLLPDGKVKHIEELRQHAGNRIAFVGDGINDAPVLALSNIGIAMGGLGSDAAIE
                     TADVVIQTDQPSKVATAIRVAKHTRRIIWQNISLAFGVKLLVLVLGAGGLA"
     PFAM_domain     complement(17266..17898)
                     /aSDomain="Hydrolase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00702.28"
                     /description="haloacid dehalogenase-like hydrolase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1556_0027"
                     /evalue="3.50E-33"
                     /label="ctg1_1556"
                     /locus_tag="ctg1_1556"
                     /protein_end="553"
                     /protein_start="342"
                     /score="115.8"
                     /tool="antismash"
                     /translation="VNTVVFDKTGTLTKGTFNVQSCETQPGISEEKLIQLAASVERNST
                     HPIAKAIVSYARERNIALEPTTEVTEIAGHGLVTTIGGKRILAGNIRLLSKYQINYPEE
                     LSLISDTIVACAMGTEYTGYLLLADTLKEDAVQAVNELKALNINNIQILSGDKQAIVTN
                     FAQKLGVREAYGDLLPDGKVKHIEELRQHAGNRIAFVGDGINDAPVLA"
     PFAM_domain     complement(17947..18501)
                     /aSDomain="E1-E2_ATPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00122.22"
                     /description="E1-E2 ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1556_0026"
                     /evalue="4.20E-41"
                     /label="ctg1_1556"
                     /locus_tag="ctg1_1556"
                     /protein_end="326"
                     /protein_start="141"
                     /score="140.6"
                     /tool="antismash"
                     /translation="RPETATVIKENEPVVETPQKVQVGEIIEVKAGERVPLDGVMQSEA
                     AAFNTSALTGESRPRSIRRGEEVLAGMIVTDKVTRIQVTRPFENSALSRILELVQNASE
                     RKAPAELFIRKFARIYTPIVTVLAVLTVLLPFIYSLINVQFTFVFDDWLYKALVFLVIS
                     CPCALVVSIPLGYFGGIGAASR"
     CDS             19088..20125
                     /locus_tag="ctg1_1557"
                     /transl_table=11
                     /translation="MRHFFLFTCLAVNFLFVGCGNRKDGPVFIVVPDAVLADSASADTI
                     VVELPFEEKLLAASDITLVKELLYDKYTLEDSYPYKDTVRSFKWEVIRNCLAYIENMQR
                     DTAKWVVLQNYKNLNNEAPLVRRFVRDAYHRVADTFGVERYQSVPLYLFADTVVPERYG
                     RDGTLAHLIGEEGSFCRIRPVTLEDEWLAPRRYLKLLGDTAVFNHVVFVDRLDQNITAL
                     ECTGKGEWKIRSMNPATTGRHAPPYAQETPLGMYLLQQKKTRMVFLKDGSAATGGYAPY
                     ASRFTNGAYIHGVPVNVPRTSMIEYSGSLGTTPRSHMCVRNATSHARFIFDWAPVERAL
                     VVVIE"
     PFAM_domain     19709..20113
                     /aSDomain="YkuD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03734.16"
                     /description="L,D-transpeptidase catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1557_0028"
                     /evalue="4.30E-09"
                     /label="ctg1_1557"
                     /locus_tag="ctg1_1557"
                     /protein_end="342"
                     /protein_start="207"
                     /score="37.1"
                     /tool="antismash"
                     /translation="HVVFVDRLDQNITALECTGKGEWKIRSMNPATTGRHAPPYAQETP
                     LGMYLLQQKKTRMVFLKDGSAATGGYAPYASRFTNGAYIHGVPVNVPRTSMIEYSGSLG
                     TTPRSHMCVRNATSHARFIFDWAPVERALVV"
ORIGIN
        1 atgcgtggaa agtgcttcag ccacaccaat cgcaagacgt aggtgaagtg aacggggaga
       61 ctgtttccgc ccaggattat cagacaatgg tagaggaata tacggaagtt gtgaaatttt
      121 ccagtggcgt gagtgcattg agcgatgaac agacaaacca gatcaaagat gaagtatgga
      181 gaagatacgt ggaaaacaag ttggttgaaa aggaagctaa gaaactgggc ttgacggtat
      241 ctaaagctga acttcaggct attattgatg ccggtgtaca tccgatgttg cagcagactc
      301 cgttccgcaa tccgcagacc ggcgcttttg acaaggacat gttgaaaaag ttcttggtgg
      361 attattctaa gatgaacaaa gctcaaatgc cttctcaata tgccgaatac tacgattcca
      421 tgtataagtt ttggtctttt atagagaagt cgcttgtaca ggctcgtctg caggaaaaat
      481 atcaggcttt gattaccaag tctctgttct ccaatccggt ggaagcacag gatgcttttg
      541 atgcaagggt gaatcaatcc gatttgttgc tgactgctat tccttattct tctattgtag
      601 attctacaat tacggtgaca gaaggggaat taaaagctgc ttatgataag aagaaagaac
      661 agtttaggca atatgtcgag gctcgcaata taaagttcat agatgtgcag gttactgcaa
      721 gcccggaaga taaggctgcc attcagaaag agatggagga atatacgact cagttggctg
      781 gaactccctc cgattatacg acttttgtcc gttccaccgg ctctactgtt ccttatgtag
      841 atttgtatta tacatccaaa tctttgcctg ctgatattgc agcccgtctg gattcagtat
      901 cggtgggtgg tgtatatggc ccttactata atgtaactga caatacaatc aattctttca
      961 aaaaattggc atccgttaca atggctgact ctatagaatt ccgtcagatt caagttacgg
     1021 cagaagatgc tggtaagact aaatctttgg cggacagtat ctataatgca atcaaaggag
     1081 gagcgaactt tgccgatgtt gctaagaaat atggacagac cggtgagcct acatggatat
     1141 cttctgccaa ctatgaaggt gcacagattg atggtgataa cttgaaatac attacagcga
     1201 tcactacttt ggggcagaat gaattgatga atcttccgtt gggacaggca aatgttatct
     1261 tgcaagtcac cgataagaaa gctaacaagg acaagtataa agtggctgtc atcaagcgtc
     1321 cggttgaatt cagcaaggag acttacagta aggcatataa tgacttcagt cagtttattg
     1381 ctgctaataa tacattggaa aaaatggtgg ccaatgcaga agatgccggg tatagacttt
     1441 tggataaaac cgacttgtat agttctgaac acggcatagg tggtgtgaag ggtactaaag
     1501 atgctttgaa atgggcgttt gaggcgaaag ccggtgaagt ttccggattg tatgagtgtg
     1561 gtgaaagcga ccgtatgctg gttgttggcg tagcaagcat tgttcccgaa ggttaccgtc
     1621 ctttggcttt ggtgaaggat cagttgaaat ttgaaattat tcgtgataag aaagctgaaa
     1681 agattatggc tgatatgaaa gctgctaacg caacttcatt tgaccaatac aagaatatgg
     1741 caaatgctgt tagcgactct gtaaaacatg tcacttttgc agcttctgca tacgttccgg
     1801 ctttacgtac cagtgagcct ttggtaagtg cttatgctgc catggctgac ctgaacaaac
     1861 ttagtgctcc gatcaagggt aatggcggtg tattcgttct tcagccttat gcaaaagaaa
     1921 agttgaacga aacattcaat cgtgaaactg aagaaacgac tttagctaat atgcatgccc
     1981 gtatggcaag tcagttcatg agtgacttgt atttaaaggc cgatgtgaaa gataaacgtt
     2041 atttattctt ctaaaaggga aacaggtata agaaaagccg tccggtaaaa ttgccggacg
     2101 gctttttttc gttatctgta tggttcattt tcggcttgtg tcattgcctt tgtgcaactt
     2161 tatttttacc tttgcacgaa taaatgataa tttagagtta gataatgcaa aaacaacctc
     2221 ttttgggctt aacgctttct gaactgcaga atgtagtaaa gaatttggga atgcccggct
     2281 ttgccgccaa acagatcgct tcgtggctct atgataaaaa agtgctttct atcgacgaga
     2341 tgagtaattt gtcattgaga catagggaat tgctgaaaga actttatgag gtcggtgctg
     2401 agattcctgt agatgctatg cgttctgtgg atggtacggt gaaatatctt tatcgtgccg
     2461 gagaggggca ttttgtagaa gcggtatata taccggatga cgatcgtgcc acactttgtg
     2521 tctcatccca agtgggttgt aaaatgaact gtaaattttg catgactggt aagcaaggat
     2581 ttacagctaa tcttaccgct aatcagatta taaaccagat cagttcgttg cccgaacgtg
     2641 ataagctgac aaatgtggtg atgatgggta tgggggaacc tttggataat ctggacgagg
     2701 tgttgaaagc tttggaagta atgacagcgt cttatggtta ttcctggagc cctaagcgca
     2761 ttacactgtc ttctgttgga ttgcggaaag gattgcagcg ctttatagag gaatctgatt
     2821 gtcatcttgc cattagcctg catactcctg ttcctcttca acgccgtgaa ctgatgcctg
     2881 ccgaaaaagc tttttccata acggaaattg tagagttgtt aagaaactat gatttcagta
     2941 aacaacgcag gctgtctttc gaatatatcg tttttaaggg agtgaatgat tctttgctct
     3001 atgctaaaga attgttgaag ttgttgcgcg gtcttgattg cagaataaat ctgatccgtt
     3061 ttcatgccat accggaggtt gacttggaag gggctgatat ggagactatg actgcattac
     3121 gggattatct taccgcacat ggattattca ccacaatacg ttcgtcccga ggagaagata
     3181 tctttgccgc atgcggcatg ctttccacag ctaaacagga agatgataaa caagaattaa
     3241 tataaattat taactttagt atggaggata tacgcattct tcgtagcttt gtgaaaacta
     3301 aaaatataga gatatgaaaa agcacttgtt ttatttaggt atgactctcg tactggcgct
     3361 ttttgccgga tgcagtaacg gaaaaaaggg tgtgtttact ccgacttcaa gtggtcgtgc
     3421 atatgaaatc ctggtagtgg ttactcccgg agtgtgggaa cgtcctgcag gcagagcttt
     3481 gtttgatgtg cttgattctg atgttccggg tcttcctcag tctgaacggt cgtttcgtat
     3541 catgtacaca gctccttcca attacgatgc tacattaaaa ctgattcgta atattattat
     3601 cgtagatata aacaaggatc tttatactca acctaaattt aaatatgcta aggatgtata
     3661 tgccgctcca caatctatat tgaccattca ggcgcctgat gaagcttctt ttgagaagtt
     3721 tgttgaggaa aacactcaag tggtcattga tttctttact catgcggaaa tgaaccgtca
     3781 gattgcggtg ttgaaagaca agcatagcga ttatgtatct acaaaagtga aaggtctgtt
     3841 tggttgtgat gtgtggatac cgggtgaact gactgccact aaggaaggca agaatttctt
     3901 ttgggcgggt acgaactcgg ctacgggcga tcagaatttc gtaatctatt cttatcccta
     3961 tacggacagg aacacattta ctaaagaata ttttatacac aagcgtgatt ctgtgatgaa
     4021 agaaaatatt ccgggagccc gtgaaggcat gtatatgatg acggattcct tgatgacgga
     4081 tgtacaccct atcagtgtgc agggtgacta tgcattggaa gccagaggat tgtggcgtgt
     4141 gaagggagac ttcatgggtg gtccgtttgt ttctcacact cgtttggaca aagcaaacca
     4201 gcgcatcatc gtatctgaaa tatttattta ttcaccggat aaaatgaaac gtaatttggt
     4261 tcggcagatg gaggcttcgc tctatacctt gaagttgcct gacaacaaac aggaaagtgc
     4321 ggaaattccg gtgaacgtag cttcaaaaga ttctattaat aacaagaaat aaaatggaag
     4381 acaataaaat aagagtaggc attacgcaag gtgacatcaa tggggtggga tatgaagtga
     4441 ttctgaaaac attttcggat ccggtgatgt tggaattatg taccccgatt atttacggtt
     4501 cgcccaaagt ggctgcttat catcgtaaat ctcttgattt gcctactaat ttcagtattg
     4561 taaattcagc ttcggaggca gcctacaatc gcttgagtgt ggtgaattgc acagatgatg
     4621 aagtgaaagt agagttttcc aagcctgatc ccgaagctgg gaaagctgca ttcggcgcat
     4681 tggagaaagc tatcgaagaa tacaaggaag gattgataga tgtgattgtt acggctccta
     4741 tcaataagca taccatccag tccgatgaat tctcttttcc gggacatacc gaatacattg
     4801 agcagaaact gggcaatggt gaaaaggctc ttatgatctt gatgaaggat gatttcaggg
     4861 tggcattggt aacgggacat attccggtaa gtcagattgc atctactgtc actaaagagt
     4921 tgatacagga aaaactgtct atcttcaatc gttctttgaa gcaggacttc ggtattagtg
     4981 ctccacgtat tgctgtgttg tctttgaatc cgcatgcagg agacgaaggc ttgctgggaa
     5041 tggaagaaca ggagatcatt attcctgcct tgaatgaaat ggcggcaaag ggtatgcttt
     5101 gttatggccc ttatgcggcg gatggattta tgggatcggg taactttact catttcgacg
     5161 gtgtgttggc aatgtatcat gatcaaggtt tgtctccgtt caaggctttg gctatggatg
     5221 aaggagttaa ttatacagcg ggacttcccg ttgtacgtac ttcgcctgct catggcacgg
     5281 cttatgacat tgcgggtaaa gggcttgcct cagaagattc tttcaggcag gctgtttatg
     5341 ttgctattga cgtgtaccgc aatcgccagc gtgacaaggc ggctcgtacc aatcctttgc
     5401 gcaaacaata ttatgagaaa cgtgacgaca gcgataaatt gaagcttgac agtgtagaag
     5461 aagatttata gtatgacgaa agcggaaata caacaagtga aattgcgttt tggtatcatt
     5521 ggtaacaatg aggcgttgtt acgcgcaatt gatattgcca ttcaggtggc gcctaccgac
     5581 ttgtctgtgc tgattaccgg tgaaagcggt gtgggaaaag aaagctttcc gcaaattatc
     5641 catcaatata gccggcgaaa acatggacaa tacattgccg tgaactgtgg agccattccg
     5701 gaaggaacca tagattctga attgttcggt catgagaaag gggcttttac cggagctatc
     5761 ggagaaagga aaggctattt tggtgaagcg aatggaggta ctattttttt ggatgaagtc
     5821 ggtgagttac ctttgcctac ccaagcacgc ctacttcgtg tacttgaaag cggtgagttt
     5881 atcaaggttg gatcttccaa agtagagaaa acagatgtac gtattgttgc tgctaccaat
     5941 gtgaatttga cacaagctat tgctgacggg cgttttcgtg aggatttgta ttatcgtttg
     6001 aatactgttc ctattcaaat tccacctctg cgtgaacgtg gagaggatgt tgtgttgttg
     6061 ttccgtaaat ttgcatcgga ttttgcggaa aaatatcgta tgcctgccat tcagttgaca
     6121 gaggacgcca aacaaatatt attgtcctat tcatggccgg gcaatgtacg ccaactgaag
     6181 aatatcacgg aacaaatctc cattattgag acgaaccgtg aaataaattc gactatttta
     6241 aaaggatatt tgcctgagca aagcaatatg cagcgcctgc ctgcattgtt tggtgtaaag
     6301 gataccaagg gttttgagag tgaaagagag atattgtatc aggtactctt tgatatgcgt
     6361 caggatgtaa cggaattaaa gaagttggtg catgagatta tgaccgaaca ggggagggga
     6421 gtcgtaagcg ctccagcagt cactccttct acttattatg caccgaatgc tccggcagtt
     6481 acgcctccgg taacttccgg catgcctacc attatacatc ctgctgtaaa accgacttct
     6541 gctgtggatg atgacattca ggatacggaa gagtatgtgg aagaatctct ctcgttggat
     6601 gaagtagaaa aagagatgat acgtaaagcg cttgaaaagc atcatggtaa acgtaaaagt
     6661 gcggcacagg atttgaatat ttccgagcgc accttataca gaaagataaa agaatatgga
     6721 ttggattaaa aaaacaacgc cggttgtctt cttggtaatt ttgggctttg tggtatgttc
     6781 ctgcaggatt tctatgggac ttgctccgat tagctctatt gactatacta aagtaaagac
     6841 tatttctatc gctgattttc agaatcgtgc agagtatgta tatgcaccgt tggctacgga
     6901 gtttaatcag aaactgaaag atatgttcat acagcagacc cgtctacggt tagtggattc
     6961 aggcggtgat cttgagatta gtggtgaaat aaccggttat aatcaatata atgaggcggt
     7021 agatgccagt ggctattctt ctaaagtgaa gctgacattg acagtcaagg ttacttatgt
     7081 taacaatgca gatcataaag atgattttac ggaccagcaa ttttccgctt tccagactta
     7141 tgattcttca caactgctaa cagcggtaca agacaatctg ataaccttga tggtgaaaga
     7201 tattacagaa cagatattta acgcaactgt agctaactgg taattaaaat gacatctgcc
     7261 catttgcaac aatggattca gcatcctgaa acattggata gagattcctt atacgaactt
     7321 cgtactttgg tgacacgcta tccgtatttc caatcgcttc gtctgcttta tctcaaaaat
     7381 ctttatttgt tgcatgacat taactttggt gctgaattgc gtaaagctgt attgtatgtg
     7441 gcagaccgtc gtatgctgtt ttatctcata gaaggtgacc gttatacttt aaagtctcag
     7501 aaatcctctc tacttttttc cagagtgata gaagacgaac ccagcgtaga tcgtaccctt
     7561 tccttgatag atgcttttct tgctacggtt cctgaagaac atcctcgaaa tatggaattg
     7621 gattatgcga tggactatac atcttatctg atgcaggagg aagaaacgga cggacaattg
     7681 gaagtttgtg cggaagcggt ggagataccc aagttgcgcg gacatgagtt aatagatggt
     7741 ttcctactga aaagcgaggc agcggatatg cgtctgcttg agatgaaacc ggatattgaa
     7801 gaagagcatc cggcaggaac taatgtgggg gaagtgcggg atgaggaaac agaggcttct
     7861 gaaatgaaag aggcgatgga ggatgaaact cctgcggaat ctcacgtcgt aggagactcg
     7921 gatgatagtt gttttacaga gacgttggcc aaaatctata ttaaacagca tagatatgac
     7981 aaggcacttg aaattattaa aaaattaagt ttgaattatc caaaaaaaaa tgcttacttt
     8041 gcagaccaaa tcagattttt ggagaaattg attattaacg ctaaatcgaa ataacaaaat
     8101 gtacttatta ttaattatct taatggtgat tgcatctgtg ttgatgtgct tcattgtgtt
     8161 gattcagaat tctaaaggag gtggtctggc atcaggcttc tcatcgtcca atcagatcat
     8221 gggcgtgcgc aagactactg acttcctgga aaaagcaaca tggactctgg ctgcagtcat
     8281 ggtagttttc agtattgctt cggcttacac tattccttct tcttcggcca agagtgggga
     8341 tgtgattatg gagcaggcac agcaagaaga aaaaactaat ccttataaca tgcctgtggg
     8401 tacggctgct ccgcagactg aagctcctgc tgctcctact gaacagccgg ttggtgaata
     8461 aggtagtgaa gaatgcggtt cagagaactc ttgctcaatg aaaaaaaaga aaggttgata
     8521 tccgaagagg tatcagcctt ttttcttttg aacaaggatt tgtttacctt tgccgagaat
     8581 aatgcaattt gattattaaa ttcataaata taatgacaga acaacttaaa cttaaattga
     8641 acgactccaa ggcaactcgt tggggagcgt tggtgattgt agccttcact atgatggcgg
     8701 cctattatgt aaacgatgta gtggctccat tgaaaacaat gttggagaca gacttggctt
     8761 ggacgagtac tgactttggt ttctttacag gaggatacag ctttctgaat gtgttttttt
     8821 tgatgctgat ttggggcgga ttaatactgg atcgctttgg cattcgtttt accggaaagt
     8881 tagcaactat cctgatggta ggaggtacgg ctttagaata ttatgcaatg accgcgcttg
     8941 ccgatgcaga tgcaacaatc tttgggataa aagagattct gggatataaa acaggtgtgt
     9001 ttattgcttt tgccggatat tctatatttg gggtgggagc tgaagttgcg ggaatcactg
     9061 tttctaaaat catagcaaag tggtttaagg gcaaagaatt ggctactgct atgggggtac
     9121 aggttgcctt ggctcgtatc ggttcgcagg ctggttatgc tgtagccatt cctatggcac
     9181 gtgccttggg gatctcttct ccggtgttgt taggcttgat attgctttta ggaggtatgg
     9241 tcgctttctt tgtcttctca gtaatggata agaagttgga taaacagatg gaagctgctg
     9301 ctatagcagc aggtacagaa aacgaagaag aaaaattctc atttaaggat gtgaggaata
     9361 ttcttggtaa tccgggattt tggctgatag ctttgctgtg tgtcttgttt tattcatgtg
     9421 tattcccttt ccaaaaattt gcttctgaat tgatgattct aaaatatggt attggtgaaa
     9481 atgtagcagg tgcttttgcc ggattgccgg ctttgggggc actgattttg actcctgttt
     9541 ttggtggctt tattgataaa cgtggaaaat cagcttctat tatgctgttg ggatcagcta
     9601 tgttgatttg tgtacacttt atatacgcaa ttccgtttat tcaattctgg ttggtagcta
     9661 ttgtactgat gattgttctg ggtattgctt tctcattggt tccgtcagca atgtggcctg
     9721 cagtagctaa gatatttccg gttagccagt taggtacagc ttatgctttg attttcttta
     9781 ttcaaaatat tggtctatgg ggtattccta cgttaattgg taaggttctt gatgtatatt
     9841 gtataacagg taagaatcct gacggaacga gtatctatga ttatacaata ccgatgtgta
     9901 tctttacagg aatagcttgt ttatctctta ttattgctct gttattgaaa aaggcagata
     9961 aaaaatacgg ttataagctg gaagaaccga atatcaaaga gtgaatctgc gaacggacgt
    10021 atataatatg gaaacactcg aaggaaaagt cagcttgttg gatgctgttc cggttcgttg
    10081 cggacatatt gggactgaat gggaaggcga atgcgtcgtg ttgtcctatc ctcgtttcaa
    10141 gtacgaatgg atgcgccgtt tcctgttgcc taaagggatg tcgcctgata tttatgtgaa
    10201 attggaagaa catggcactg ccgtatggaa tctgattgac gggcatcgta cggttaggca
    10261 gataatttcg ttgcttgcag ggcattttga aggtgaagac aattatgagt cacgtgttac
    10321 cacttatgtg atgcaattaa ggagagacgg atttatccgg ctgacagtaa ggaaaggctg
    10381 aaaaggagtt gtatttaaat aataaaggct gcgcaatgtc atgatgagcc atttctctga
    10441 ttgcgcagcc tttttattat gattcttgtc tattccctat ctacttttat taatcctcct
    10501 gttgccgtgt cgaacaaaac tttgatcgtg gagttcttgt tgaataagac cggggcaaga
    10561 tattctatga tgccgaattg ggtgataggg aattcctcct caaacagttt cttgtttttc
    10621 tgtaccaaag tgacttttgc cctgcccggt acattgtaag caataccttc tgttttcttt
    10681 ttactttcct ctgtgccgga cgtatcgggt gttttgagat cggttatgct gatgtaatat
    10741 ggctcaccgg caaaatcatt gttggctact atgcccagtt tcttggagaa gcggaaagca
    10801 atttcgtctt tcatttcctt cggggtgata cggatggtaa atgtgccgga ctctgatttt
    10861 actgtgcctg agaacatttc agtcatggca agttcttgca agttcagatt gtcaagcatg
    10921 agtttgagtt gtgtgccatc tttgggcatg ttgtccgctt cgccacgcag caaggcattc
    10981 ttgctttcgc ggatattata gatttctttg gcgaccagtt cagccatttt tgcacttgaa
    11041 ttggacataa gaatttcttc tgtcagaaaa ctgcgtggat caatgctgtt ttcagggctt
    11101 ccgatggtct tcacggcttt gtcgggcttt tgtccgctga ggggcatgtt gatggagcgt
    11161 acaattccgt cttcggtaag ttccataagc ggagctacgg ttttatcttt cagtttgacg
    11221 aaatatacat tgtccttgtc cggtatgcct gctatgcggg gttgtatctt gtccaaagtc
    11281 caatatgctt ccggttcggc tgatacgtta ccgaggcgca gatagcggtc ggcgtatttg
    11341 cagaattctc cgggggtata tgtgtgtttg gtgatttgca atacaatttc tatttctgtt
    11401 ttgggcaaca agtaagttac tccgtactct ttgccacgca ttacccctgt cgtgacttct
    11461 gtctgcgcat ggacaccggt ggcgatcagt aaggcagaga tccataacaa tttctttttc
    11521 atatcgttga gtctgtttat attacatgaa tttagataac aaagttaact aagttctctt
    11581 gttcccgggt tgtcgtttac gaaagattaa ctaataggta ctttcataga cagccattta
    11641 ttgtacaaac tgtatgcaga caggtttgtc aactgtgata ttccgatggg tatctttcaa
    11701 caatcctgtt gttgcgttgc gttcatatat ttggatggta ttgctgtcac ggcatgcggc
    11761 aagcaggtat ttgccgttcg gggtaatatt gaagtggcgc ggatggatac ctgtcggctg
    11821 gtagcctgct ttggccagag tgccattatc cggactgacg gcaaagatgg cgataccgtc
    11881 ttcccggaga cgattgctgg catagaggta ctttccatcc gggctaagat ggatatcggc
    11941 actgccacgg gcagctatgg tgtcggcggt aatagtctgt atctgttcca gtttgccatt
    12001 gtcatagctg aaagcgatga cttttcctga taattcggta ataaggtaag catactttcc
    12061 gttgggactg aatgtcaagt ggcgcggtcc ggaacctgga gcaatgtctg tggtttcggc
    12121 tgaaagatgg gggatgatat ctttaggatg caagacgaaa cgcaaaatgc ggtcggcact
    12181 aaagtctgtg gcaaatatgt actttccgtc cggtgagaaa acggtgcagt ggatatgggc
    12241 tgtaatctgc cgtatggtgt cggttccggt ggcactgcct ataaacagag tatccacagg
    12301 tcctaaagta ccgtccttgc gaagagggaa gacagacatg cttccgccac tataattggc
    12361 ggttagtgct tctttcccgt tggtggccac atagcagggg tcggcgccga gggtaggttc
    12421 ggtattcagc aggcgcagga tacctgttga tttatcaaat gcgaaggaac tgagggcggc
    12481 cgtgctgtca ttcatttcgc tgacagcata tacaaatttc ccgtcttcgg atgggatgag
    12541 gtatgaggga ttgggtaatt ccatagtact gagaggaatg gctgtacccg tctcctgatt
    12601 aaagcggaag gtatagattc ccttgcttgt tccgttggta taagtaccca ccagcatggc
    12661 gagttcatcc gaggttttgt ttactgcctt tcggggtgtg caggcggcta cgcttaggcc
    12721 aagcatacaa tagagaagtg ctttcattat gctatatact ataagttttc attataaact
    12781 ggaggaaaac tacgcagttc agtgcaaaag taatggaaat ttgcagatta aaaaagatta
    12841 ggcgcagatt acatggagaa taggagagat tttgaacctg atttgtgaga ctccgtataa
    12901 tcttcgcctg aaagagttga gtgatcgggg gacgtatcat tctgtcagtt tcacttctgc
    12961 tattcctaca tggtcgtcat tcaagacaat gcgcagatca ctggcagtag tgcctttgaa
    13021 agaataggaa atcatttttc cgtattcgct gacaacacct gaatatacgg tcaggaactg
    13081 tcctccgcca cctgaaagtt ggatatcgaa atcggcaggt agattgttgt cgcgcatgaa
    13141 agcgatggaa accttgtttg tttggattcc gttgcccaaa gcaaaggtga tgtaatcacc
    13201 tttgttgcct tgccatgccg tgtcgattct tccatcggtc gcattgcacg cattttcccg
    13261 attggcgctg gcactcacac gttcggctgg tttactggtt tcaattgcct tggctcgcat
    13321 ttggtagtcc tctacggtca atagcccgtt caggcggatg tcttcggaag aagcggccgc
    13381 catgatggtg aagtctcccg gttctaccac ccactgcatg ttggcatcaa ggagttccag
    13441 atgtttgcgg ccaagggtga agactacttc tttagtttct cccggttcaa ggtggacacg
    13501 ttcaaatcct gccagatttt tctcatacgt gatgacactg cttaccacat ctctgatata
    13561 gagctgtact acttcatctc ctgcacgttt tccggtattg gtcactttca gacgtaccgt
    13621 tgcttcttcg ttgggagtaa tgactttggg agtgatttca aggtcggaat actcgaaggt
    13681 cgtgtagctc aatccgtaac caaaggggta gagtgcgcca ttgatgcgcg acatattgcc
    13741 ttccggtccg ggatttttgc caccgtcaat ttgtgaggca ggcttatagg ggaagttgaa
    13801 cgggatctgc ccgacggttt tcgggaaagt cacggtcagt ttgccccccg gattatagtc
    13861 cccaaacaga acgtcggcaa gggctatgcc gccttttgct cccggatacc atgcttcgag
    13921 aatggcgggg acatacttgt ccgcccaatt cacggataac ggacgtccgt tgatgagtac
    13981 caatattacg ggctttcccg tagcttgtat ggcctggagc agttgtaatt ggcggccagg
    14041 tagatccaga ctgctacgtg acttattttc accgcatgtt cgttggccac cccccaatac
    14101 gactactgcc acatctgatt ggcgggcatt ttccgcggct ttgtttattt cagcctgttc
    14161 gtcggcggtt agaggatgat ttatgatctc actttcgggc cagttggcat ccaccaggtc
    14221 gcaacctttg gtgtagagca cttcggcttt gccgcttact ttgtcctgaa tccctttcag
    14281 cacagtgatg acttctacgg caagggggcc ataatgagtg agtgcgtaat tcttttcatc
    14341 ggcattgggg ccgcatacgg caatcctttt taccgtactg agatccagag gcagcatgtt
    14401 attctcgttt tttagcagaa cgatggactc gcgggacgcc tgtagggcaa tgcttccgtt
    14461 ttcttctttt tctacttctc tgtcggctcc ggcaaggtcg gattggtaag gagtgtcaaa
    14521 taatccggta aggaatttta cgcggagaat gtcacgcaca cgatcattga tgatttcttc
    14581 actcagtcct ccctctttta ccaattcgcg gagggggagc acgaaagaat ccggagaacg
    14641 gaaagtgcag cgtatgttca gcccggcttc tacactttgg cgtattgcct ctttcatgtc
    14701 tttggcagta ccgtgcttgg tgtagaggta ttctacggcg tcactgtccg ataccacata
    14761 gccacggaaa cctatttcgc cgcgcaggcg ggtagtcagc cagtagtggc ttccttgtat
    14821 gggaatgcca tcatagtcat tgtacgaact cattacgccg agcagtccgg cttccctgat
    14881 tacccgtctg aagggataaa tgtggatatt ttccacttct cgcggtgaga tctgcggatc
    14941 cacacgcgac attccttcac gggcaccttt gttgttgctg taagcggcga aatgttttcc
    15001 ggtggccgcc acctggtgat tgtactgcat gccgcgtacc atctcaatgc ccagctcagc
    15061 tacaaggtag ggtgattcgc catatacttc ttcatagcgt ccccagcgct ggtcgcgtcc
    15121 tacatcaaga atgggggcat atacattggt atagcccaac atacgcgcct cgcgtccggt
    15181 gataaatcct atcttatgga tcagttcacg gttccaggtg tgccctaagc ccagttgggt
    15241 gggaaagttg gttgccttgt agctttccac accccggatg ccttcgttag tgaaatctac
    15301 tgggattccg aggcgggttt cttccacaaa gaaacgctgt acttcgttca gtgcccatgc
    15361 gtggcgggaa gcaggccaga cgttctcatt gtccgaagga ggaagccccc attgccgaaa
    15421 gccattcagg tgttcgtcaa tggctcctat tccgtctttc cacaacattt gtttccattc
    15481 gggagtgggg aggtcatctt tcaatactcg tttgtagccg taaagggtaa ccatctggca
    15541 ggttttctct tccaggctca tctgttttag taaatcttca atgcgggcat caatggcggc
    15601 tgtgggatct tcgtatatgt ccataatgcc gtttttgttg aaatcaatcc aacctttacg
    15661 atacatttca cttttcaccg gcttgtatat tgccggtatt ttcatcgttt tctgtgctga
    15721 gagcaaagca ccgttgccca gcagcaaaac ggctacaatc agttttctca tgacggttta
    15781 tttttctttt aatgcaaaag tagggcattg ctccgtaacg gggtggctaa aatagtccat
    15841 attttcctct tatattttcc ggacgtctgt tttgcgggag tggcatacat gcttcctgct
    15901 tccattgtaa actgtaaact tgataataat tgctaagaaa taaagcatga taataaaaga
    15961 tttcctatct ttgcggcaga taaagcaaga ttattggcag ataggatgcc ttcatttgct
    16021 actcaatatt aaatgaatgc ctccttcctt gctggtttcc tgtaagttat aagaacatgg
    16081 gcttgactgg atttgacagc gggcagaaat ggtaagtaag catgcagtgc gttgttgatt
    16141 tgcacttaaa tctcagtctt caaaatttta tctggcgaaa acaattacgc tcttgctgct
    16201 taatcgaatc acagtagatt agcttaatcc cggcacaagg tgctgggacg ggacatcact
    16261 cggaagctgt tgctccgaag cattccggta aagtggtgca gttacatcgg ggatagtttg
    16321 cacttgcctt gaagtgcgaa tgaaatttag aggataaggt gacggttgat ggctttggtt
    16381 ctgccgccac acgaaaactt aggcaaagat aagcatgtag aaagcttatg atttcctcgt
    16441 ttggacgagg gttcgattcc ctccaggtcc acgtgccgga aggcgatgga aaggaggcgg
    16501 cacttaatag atgccgcctc ctttccgtta ttttaaaacc tttgccgcac actcaggaca
    16561 aagccctttc agtacatagt tgatactatt cagcgtaaat ccttcgggca ggttcaccac
    16621 cggtgtgggg atgttcttga aacagaatgt cttgttgcac ctctcacaat gaaagtgagt
    16681 gtgcaggtcg tttacttcgc aagaacaact tgcactgcac acggcatatt tgaatgagcc
    16741 ggttccatca tcaatgctgt gtataaggtg gtgggataaa aataaagtga tggtgcggaa
    16801 aatggtggat ttatccacgg tgtccagtat gttctccaga tcgagcaacg agacggaacg
    16861 ccttgtcttc agcatggctt gcaataccag tatgcgtatg gcggtgggct gtatccctct
    16921 ttttgccagc aggtctaaat ataaattttc ttccataatc cttcattatt ctattttaat
    16981 gaatttctgt attcgtatag catttactat tgcaatgagt gcgacgccta catccgcaaa
    17041 tacagcttcc cacagtgtgg ccagcccgcc ggcgcccaaa accaatacaa gcagttttac
    17101 cccgaaagcc agagatatgt tctgccagat aatccggcgg gtatgttttg ccacccggat
    17161 ggcggttgcc actttcgatg gctggtcggt ttgtattacc acatctgccg tttcgatggc
    17221 tgcgtcacta cccaatcctc ccatggcaat gcctatatta ctgagggcga gaactggtgc
    17281 gtcgttgatg ccatcaccta caaaagcaat tcggtttccg gcatgttgac gtagttcctc
    17341 aatgtgtttt actttaccgt cgggcagcag gtcgccgtat gcttccctga ctcctaactt
    17401 ttgcgcaaag ttagtcacaa tggcttgctt gtctcccgaa agtatctgaa tattatttat
    17461 atttaaagct tttaattcat tgaccgcctg gacggcatct tctttcagtg tatcagctaa
    17521 tagcaggtag ccggtgtatt ctgttcccat ggcacatgcc acaattgtgt cggagatgag
    17581 tgatagttct tcgggatagt ttatttgata tttggacaat agacggatat ttcctgccaa
    17641 aatgcgtttt cctccaatag ttgttaccaa tccgtgaccg gcgatttccg taacctcggt
    17701 agtaggttcg agtgctatat tacgctctct ggcatagctg acaatggctt ttgcaatcgg
    17761 gtgtgtacta ttccgttcta ccgaagctgc cagttgtatc agcttttctt cggatatgcc
    17821 cggttgtgtt tcgcaggact gcacgttgaa agttcctttc gtcagtgtgc ctgtcttgtc
    17881 aaagaccact gtgttgactt gggtgatggc atccaggtaa tttccaccct taaacaaaac
    17941 gccgaggcgg gatgctgcgc ctatgcctcc gaaatatccc agtggaatgc tgactaccaa
    18001 ggcacacgga caagaaataa ccagaaatac caatgctttg taaagccagt cgtcaaatac
    18061 aaaagtgaac tggacattga tcagtgaata gataaaagga agaagcacgg tcaatactgc
    18121 cagcactgtg acgatcggtg tgtaaatacg ggcaaatttt cggatgaaca attctgctgg
    18181 agcttttcgt tcggaggcat tctggacaag ttccagtatt cttgataggg cactattctc
    18241 aaagggtctt gtaacttgta ttctggtcac tttatccgtc actatcattc cggcaagcac
    18301 ttcctcaccc cttcgtatgc tgcgcggacg gctctctccg gtcagtgcag atgtattgaa
    18361 tgctgcggct tcactctgca ttacaccatc cagaggaacc cgttctcctg cttttacctc
    18421 tatgatttct ccgacttgta ctttttgagg agtttcaact acgggctcat tctctttgat
    18481 taccgtcgct gtttctggac gtacatcgag cagagtgctg atattgcgtt tcgctctatc
    18541 cactgccttg ccctgaaaga gttctcccaa agagtagaac agcatgacag ccacaccttc
    18601 cggatactct ctaatataaa aagctcctaa agtggcaatg gtcataagcg tgaattcgct
    18661 gaaaacatct ttttccacaa tgcttttcca agcctccttc atgaccggta gtcctaccgg
    18721 cagatatgcc gatatatacc atataagagc tacatatttt tcacggaaaa aagtaatatc
    18781 catcatatcc atgatgatgc cgccgaaaag cagtaatgcc gacaatataa tcttccggta
    18841 atcttttaaa gcattcgagt ttaccggaac tttttgactc tgtgcactgt catgagcgca
    18901 gcatttacaa ttatgatgtc ccatattatt gtttttattt cggatgcaaa gttaagtaaa
    18961 ggaggatgca accaagttgc aaaggtatat cttttgcata aaatgctggg ttatgcaaca
    19021 attatcggag gattgtcgtt atttaattta aataaattat atctttgttg aaataacttt
    19081 tatcataatg aggcattttt tcctttttac ctgtctggct gtgaactttc tttttgtcgg
    19141 atgtggcaac cggaaagatg gacctgtatt catagtagtg ccggatgccg ttcttgccga
    19201 ttcggcttct gccgatacga tagtcgtgga attacctttt gaggaaaagt tgctggcggc
    19261 ttctgatata actcttgtca aagagttgct ttatgacaaa tatactttgg aggactctta
    19321 tccatataaa gatacggtgc gttcctttaa atgggaagtg attcgtaatt gtctggctta
    19381 tattgaaaat atgcagcgtg acactgcaaa gtgggtggtg ctgcagaact ataagaacct
    19441 gaacaatgaa gccccgttgg ttcgacgatt tgtcagagat gcctatcatc gtgtggcgga
    19501 cacttttggt gtggaacgtt atcagtctgt tccactatat ttgtttgccg acacagtggt
    19561 tcccgaacgc tatggaagag atgggactct ggcgcatctg ataggagaag aagggagttt
    19621 ttgcaggata cgtcccgtca cccttgaaga tgagtggctg gctccccgtc gttatttgaa
    19681 acttttaggt gatactgccg tctttaatca tgttgttttt gtggatcgtc tggatcagaa
    19741 tattactgct ttggaatgta ccggtaaggg tgaatggaag atacgcagca tgaatccggc
    19801 cactaccggg cgtcatgctc ctccctatgc tcaggaaacc ccattgggca tgtatctgct
    19861 tcagcagaag aaaacgcgta tggtctttct gaaggatggg tctgccgcaa cgggaggcta
    19921 tgcaccttat gcaagccgtt tcacaaacgg tgcttatata catggagtac cggtcaatgt
    19981 acctcgtaca tccatgattg aatatagcgg gtctttgggc actacccccc gttcgcatat
    20041 gtgtgtgcgc aatgccactt cacatgccag attcatcttc gattgggctc ccgtcgaacg
    20101 tgctttggtg gttgtcattg aataggtatg ctatttttaa ctatctgtgt gatagatgta
    20161 tggagaaaaa gttctaactt tgtccccgtt cttttccggt cagaagaatt atgcagagat
    20221 ttatattgtt ctttttactc gcgtttgttc cttgctctct gtttttggaa ggcgagccgt
    20281 tggatggtgt ggcagaagga aattcctccg ggacatttgc cgggattaca gcctgtgccg
    20341 aactttatcg ttccatgggt ttggaaggga tggtaaactg g
//
