LOCUS       NC_002516.2            10831 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_002516.2 Pseudomonas aeruginosa PAO1, complete genome.
ACCESSION   NC_002516
VERSION     NC_002516.2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:42:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 4584490
            Orig. end    :: 4595321
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10831
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[4589490:4590321](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5831)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10831
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10831
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="13"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(42..302)
                     /locus_tag="ctg1_4188"
                     /transl_table=11
                     /translation="MTRTLLATTLLAALALPAFAAQAAAPVPTESYRYGMPLDVHKVVA
                     TQEQASTTCEIVDARMDYLDSAGKLHSLAYRKYASACSQGG"
     PFAM_domain     complement(54..272)
                     /aSDomain="DUF2790"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10976.10"
                     /description="Protein of unknown function (DUF2790)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4188_0487"
                     /evalue="1.40E-21"
                     /label="ctg1_4188"
                     /locus_tag="ctg1_4188"
                     /protein_end="83"
                     /protein_start="10"
                     /score="76.3"
                     /tool="antismash"
                     /translation="LAALALPAFAAQAAAPVPTESYRYGMPLDVHKVVATQEQASTTCE
                     IVDARMDYLDSAGKLHSLAYRKYASACS"
     CDS             659..1399
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 197.3; E-value: 4.2e-60)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4189"
                     /transl_table=11
                     /translation="MEHVDHILIVDDDREIRELVGNYLKKNGLRTTIVADGRQMRAFLE
                     ANTVDLIVLDIMMPGDDGLLLCRELRVGKHKATPVLMLTARNDETDRIIGLEMGADDYL
                     TKPFSARELLARINAVLRRTRMLPPNLTVSESSRLIGFGQWQLDTSARHLLDDAGTVVA
                     LSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGREADIFDRSIDLLVSRLRQRLGDDAREP
                     EYIKTVRSEGYVFSLPVRLVEAHP"
     PFAM_domain     677..1012
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4189_0488"
                     /evalue="3.30E-30"
                     /label="ctg1_4189"
                     /locus_tag="ctg1_4189"
                     /protein_end="118"
                     /protein_start="6"
                     /score="104.6"
                     /tool="antismash"
                     /translation="ILIVDDDREIRELVGNYLKKNGLRTTIVADGRQMRAFLEANTVDL
                     IVLDIMMPGDDGLLLCRELRVGKHKATPVLMLTARNDETDRIIGLEMGADDYLTKPFSA
                     RELLARIN"
     PFAM_domain     1136..1363
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4189_0489"
                     /evalue="3.10E-21"
                     /label="ctg1_4189"
                     /locus_tag="ctg1_4189"
                     /protein_end="235"
                     /protein_start="159"
                     /score="75.3"
                     /tool="antismash"
                     /translation="TVVALSGAEYRLLRVFLDHPQRVLSRDQLLNLTQGREADIFDRSI
                     DLLVSRLRQRLGDDAREPEYIKTVRSEGYVF"
     CDS             1396..2700
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 155.1; E-value: 5.9e-47)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4190"
                     /transl_table=11
                     /translation="MKLAVPRPRSLAARLALILFAGLVLAYGLSFASQFYERYQTAKHM
                     MLDSLEQDVAISVAMLDRLTPAEREAWLPRLERRTYRYRLDAGEPGQPLALADAPVAAH
                     SIERALDGQYPLTLRTVADSRPHFQVLLRLRDGSPLTIDVTPAPVPLSGWLPLVLLVQL
                     LLLLLCTGLAVRTAIGPLTRLVKAVEHLDPNRPAQPLAETGPREVAHAAAAFNAMQARI
                     ADYLKERMQLLAAISHDLQTPITRMKLRVEFMDASSDRDKLWNDLEEMQHLVREGVAYA
                     RSMHGSTETSCRVDLDAFLDSLVFDYQDSGKQVQLDGRTGAVIDTRPHALRRVLVNLVD
                     NALKFAGAARLEVERRTDGGTRIQVLDNGPGIPAEELDEVLKPFYRVENSRNRDTGGTG
                     LGLAIAQQLSLALGGRLTLANRAGGGLCARIELDP"
     PFAM_domain     1912..2061
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4190_0490"
                     /evalue="4.20E-06"
                     /label="ctg1_4190"
                     /locus_tag="ctg1_4190"
                     /protein_end="222"
                     /protein_start="172"
                     /score="27.1"
                     /tool="antismash"
                     /translation="AVRTAIGPLTRLVKAVEHLDPNRPAQPLAETGPREVAHAAAAFNA
                     MQARI"
     PFAM_domain     2380..2694
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4190_0491"
                     /evalue="2.90E-21"
                     /label="ctg1_4190"
                     /locus_tag="ctg1_4190"
                     /protein_end="433"
                     /protein_start="328"
                     /score="76.2"
                     /tool="antismash"
                     /translation="HALRRVLVNLVDNALKFAGAARLEVERRTDGGTRIQVLDNGPGIP
                     AEELDEVLKPFYRVENSRNRDTGGTGLGLAIAQQLSLALGGRLTLANRAGGGLCARIEL
                     D"
     CDS             2830..3459
                     /locus_tag="ctg1_4191"
                     /transl_table=11
                     /translation="MTVPTSQSAWHGWRLFAVLAVAVLCMTALVLALQAQPVEGLRSAI
                     RATARSSFALFLAAFLASSLATLVPGPGTRALLRERRYLGLAFAFSHAVHALLILAYWK
                     LFPETFWSGRSVAANIPGSIGYLFILLLTLTSFRTPARLLGPRAWKALHSTGTWVLAGI
                     FCLSFFKRIPMGGWYVLAFATIFSAIVLKLTAKLAVRLRRRDVQPA"
     PFAM_domain     2983..3312
                     /aSDomain="Ferric_reduct"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01794.21"
                     /description="Ferric reductase like transmembrane
                     component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4191_0492"
                     /evalue="2.00E-07"
                     /label="ctg1_4191"
                     /locus_tag="ctg1_4191"
                     /protein_end="161"
                     /protein_start="51"
                     /score="31.2"
                     /tool="antismash"
                     /translation="SFALFLAAFLASSLATLVPGPGTRALLRERRYLGLAFAFSHAVHA
                     LLILAYWKLFPETFWSGRSVAANIPGSIGYLFILLLTLTSFRTPARLLGPRAWKALHST
                     GTWVLA"
     CDS             3491..4000
                     /locus_tag="ctg1_4192"
                     /transl_table=11
                     /translation="MQASDLRAWRRPFALLDRCGGWSADLSLRLFLAWEFFESGWEKWN
                     GENWFGDIQSAFPFPFDRLPAAFNWELSLWAELLGALFLLLGLGTRLTALVLIVVTLVA
                     TAAVHWPAEWSSLAELARGYSITDHGFGNFKLPAIYLAALLPLLLAGAGKLSLDHWLGR
                     RLGLSR"
     PFAM_domain     3563..3820
                     /aSDomain="DoxX"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07681.14"
                     /description="DoxX"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4192_0493"
                     /evalue="8.40E-21"
                     /label="ctg1_4192"
                     /locus_tag="ctg1_4192"
                     /protein_end="110"
                     /protein_start="24"
                     /score="74.5"
                     /tool="antismash"
                     /translation="DLSLRLFLAWEFFESGWEKWNGENWFGDIQSAFPFPFDRLPAAFN
                     WELSLWAELLGALFLLLGLGTRLTALVLIVVTLVATAAVHW"
     CDS             complement(4253..5008)
                     /locus_tag="ctg1_4193"
                     /transl_table=11
                     /translation="MDERLRQQQFSLARHLRDPLGNAPPPDIEERRLRVYRELFYNAIE
                     GLLASGFPRLRGLLGEQQWHGLVREFYREERSHTPLFTRIAGVFVDYLRQRGEYRPAWQ
                     AELAHFEWSETRLYLAEPDDPPYRREGDLLDGVPLLSSLALPLGYRWPVHRLEEDVALA
                     EAPAEPTLLLMHRDSSHRVHTARLTPLACRLLESLARRRLSGREHLAALALEARSAPGA
                     LDAAGLELLAALRTQGVVLGTLERDWAGG"
     PFAM_domain     complement(4730..4987)
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4193_0494"
                     /evalue="3.80E-22"
                     /label="ctg1_4193"
                     /locus_tag="ctg1_4193"
                     /protein_end="93"
                     /protein_start="7"
                     /score="78.4"
                     /tool="antismash"
                     /translation="QQFSLARHLRDPLGNAPPPDIEERRLRVYRELFYNAIEGLLASGF
                     PRLRGLLGEQQWHGLVREFYREERSHTPLFTRIAGVFVDYL"
     CDS             complement(5001..5831)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4194"
                     /sec_met_domain="DUF692 (E-value: 1.8e-125, bitscore:
                     416.0, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLIDNAAGLGLRRGLLPQLLAMAPGAVDFLECAPDNWIGVGGAF
                     GADLERLVERIPLTCHGLSLSLGGSTPLDAAFIEQTRRFLVRHRVALYSEHLSYCSDDG
                     HLYDLLPLPFTEAAVRHVAARIREAQERLERRIAVENISYYAAPYREMSEIEFVNAVLD
                     EADCDLLLDVNNLFVNACNHGYDALDFLVRLPPGRVAAYHVAGHYDEAPDLKIDTHGAA
                     VKPGVWALLGAAYRRFGVRPTLLERDFNYPPLGELLLEVEQIRQWQRDEGRRHG"
     PFAM_domain     complement(5028..5810)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4194_0495"
                     /evalue="5.10E-98"
                     /label="ctg1_4194"
                     /locus_tag="ctg1_4194"
                     /protein_end="268"
                     /protein_start="7"
                     /score="327.6"
                     /tool="antismash"
                     /translation="AGLGLRRGLLPQLLAMAPGAVDFLECAPDNWIGVGGAFGADLERL
                     VERIPLTCHGLSLSLGGSTPLDAAFIEQTRRFLVRHRVALYSEHLSYCSDDGHLYDLLP
                     LPFTEAAVRHVAARIREAQERLERRIAVENISYYAAPYREMSEIEFVNAVLDEADCDLL
                     LDVNNLFVNACNHGYDALDFLVRLPPGRVAAYHVAGHYDEAPDLKIDTHGAAVKPGVWA
                     LLGAAYRRFGVRPTLLERDFNYPPLGELLLEVEQIRQWQ"
     CDS             complement(5906..6373)
                     /locus_tag="ctg1_4195"
                     /transl_table=11
                     /translation="MSVFDSRQKTSASLLGAVLVGGMLLGGSAFAVEPLGQGLQVAAAS
                     AGEGKCGEGKCGSGGSAKTPAKAGAEGKCGEGKCGDASFARTDTDHDGKVSRAEFLAVA
                     KDRAGEFDSIDSDHDGFISEAEAYEHLRKTYEANGKPMPAGLFSKLEQGQH"
     PFAM_domain     complement(6065..6127)
                     /aSDomain="EF-hand_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13202.8"
                     /description="EF hand"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4195_0496"
                     /evalue="1.50E-03"
                     /label="ctg1_4195"
                     /locus_tag="ctg1_4195"
                     /protein_end="103"
                     /protein_start="82"
                     /score="18.0"
                     /tool="antismash"
                     /translation="SFARTDTDHDGKVSRAEFLAV"
     CDS             6697..7941
                     /locus_tag="ctg1_4196"
                     /transl_table=11
                     /translation="VLKRIPVTQLRLGMFVQSLCGSWLDHPFWKRGGFLLDSQADLQRL
                     RESAVKEVWIDASKGLDLPEEAAVSAAAVLPVTMPAGPSPARVALEEEIRHAALLCSRA
                     KAAVVSMFRDARMGQAIDTAHASDLVDEISASVLRHPNALLSLVRLKTSDEYTYMHSVA
                     VCALMIALARQLELPDPLVREAGLAGLLHDIGKMAVPDPILNKPGKLTDPEFGLVRRHP
                     QNGARMLLDCRQVSALVVDVCLHHHERIDGTGYPFGLAQEQISLLARMGAVCDVYDAIT
                     SDRPYKKGWNAAEAIRRMAEWNGHFDPQVFRAFVKAVGIYPVGALVRLESGRLGVVLEQ
                     HGRSLLTPRVKVFFSARSKVPIPQQVVDLGRAGQTDRIVGFEPAEAWNFRNLDEMWTGL
                     AKSTGSYFDAGTGNP"
     PFAM_domain     6700..7071
                     /aSDomain="DUF3391"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11871.10"
                     /description="Domain of unknown function (DUF3391)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4196_0497"
                     /evalue="5.40E-35"
                     /label="ctg1_4196"
                     /locus_tag="ctg1_4196"
                     /protein_end="125"
                     /protein_start="1"
                     /score="121.0"
                     /tool="antismash"
                     /translation="LKRIPVTQLRLGMFVQSLCGSWLDHPFWKRGGFLLDSQADLQRLR
                     ESAVKEVWIDASKGLDLPEEAAVSAAAVLPVTMPAGPSPARVALEEEIRHAALLCSRAK
                     AAVVSMFRDARMGQAIDTAH"
     aSDomain        7159..7434
                     /aSDomain="TIGR00277"
                     /aSTool="tigrfam"
                     /description="HDIG: HDIG domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_4196_0099"
                     /evalue="6.50E-09"
                     /identifier="TIGR00277"
                     /label="ctg1_4196"
                     /locus_tag="ctg1_4196"
                     /protein_end="246"
                     /protein_start="154"
                     /score="33.6"
                     /tool="antismash"
                     /translation="EYTYMHSVAVCALMIALARQLELPDPLVREAGLAGLLHDIGKMAV
                     PDPILNKPGKLTDPEFGLVRRHPQNGARMLLDCRQVSALVVDVCLHH"
     PFAM_domain     7168..7533
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4196_0498"
                     /evalue="6.10E-15"
                     /label="ctg1_4196"
                     /locus_tag="ctg1_4196"
                     /protein_end="279"
                     /protein_start="157"
                     /score="55.6"
                     /tool="antismash"
                     /translation="YMHSVAVCALMIALARQLELPDPLVREAGLAGLLHDIGKMAVPDP
                     ILNKPGKLTDPEFGLVRRHPQNGARMLLDCRQVSALVVDVCLHHHERIDGTGYPFGLAQ
                     EQISLLARMGAVCDVYDA"
     CDS             8262..8483
                     /locus_tag="ctg1_4197"
                     /transl_table=11
                     /translation="MLESEIVAARRAYAASLGVTLSGAISNADEPVHIRHAVSNSNHNP
                     NASNRINLGRARAYKKRREEGDYFFIDT"
     CDS             complement(8500..9390)
                     /gene_functions="regulatory (smcogs) SMCOG1031:LysR family
                     transcriptional regulator (Score: 236.7; E-value: 6.1e-72)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_4198"
                     /transl_table=11
                     /translation="LVRPHLPLNALRAFEASARHLSFTRAAIELCVTQAAVSHQVKSLE
                     ERLGVALFKRLPRGLMLTHEGESLLPVLCDSFDRIAGLLERFEGGHYRDVLTVGAVGTF
                     TVGWLLPRLEDFQARHPFIDLRLSTHNNRVDIAAEGLDYAIRFGGGAWHGTEALALFEA
                     PLTVLCCPEVAAQLHSPADLLQHTLLRSYRADEWPLWFQAAGLPAHAPLTRSIVFDTSL
                     AMLEAARQGVGVALAPAAMFARQLASESIRRPFATEVSTGSYWLTRLQSRGETSAMLAF
                     RGWLLEMAAVEARGR"
     PFAM_domain     complement(8524..9120)
                     /aSDomain="LysR_substrate"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03466.22"
                     /description="LysR substrate binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4198_0500"
                     /evalue="9.10E-34"
                     /label="ctg1_4198"
                     /locus_tag="ctg1_4198"
                     /protein_end="289"
                     /protein_start="90"
                     /score="116.8"
                     /tool="antismash"
                     /translation="HYRDVLTVGAVGTFTVGWLLPRLEDFQARHPFIDLRLSTHNNRVD
                     IAAEGLDYAIRFGGGAWHGTEALALFEAPLTVLCCPEVAAQLHSPADLLQHTLLRSYRA
                     DEWPLWFQAAGLPAHAPLTRSIVFDTSLAMLEAARQGVGVALAPAAMFARQLASESIRR
                     PFATEVSTGSYWLTRLQSRGETSAMLAFRGWLLEMA"
     PFAM_domain     complement(9190..9369)
                     /aSDomain="HTH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00126.29"
                     /description="Bacterial regulatory helix-turn-helix
                     protein, lysR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4198_0499"
                     /evalue="4.00E-20"
                     /label="ctg1_4198"
                     /locus_tag="ctg1_4198"
                     /protein_end="67"
                     /protein_start="7"
                     /score="71.6"
                     /tool="antismash"
                     /translation="LNALRAFEASARHLSFTRAAIELCVTQAAVSHQVKSLEERLGVAL
                     FKRLPRGLMLTHEGE"
     CDS             9539..10732
                     /gene_functions="resistance (resist) ClassC-AmpC (Score:
                     557.6; E-value: 7.3e-170)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 167.8; E-value: 5.5e-51)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4199"
                     /transl_table=11
                     /translation="MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPV
                     MKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYAL
                     TQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYR
                     QWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAA
                     LAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDA
                     THRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLL
                     NKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLEQQGKVPLKR"
     PFAM_domain     9650..10693
                     /aSDomain="Beta-lactamase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00144.26"
                     /description="Beta-lactamase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_4199_0501"
                     /evalue="7.20E-80"
                     /label="ctg1_4199"
                     /locus_tag="ctg1_4199"
                     /protein_end="385"
                     /protein_start="37"
                     /score="268.8"
                     /tool="antismash"
                     /translation="VDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTP
                     ETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAG
                     GLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERL
                     MEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLL
                     RFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPM
                     ALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERV
                     KIAYAILS"
ORIGIN
        1 ccgcgcgaca accggccgtg caggctctgg ccggcgcctg actagccgcc ctggctgcag
       61 gcgctggcgt acttgcggta ggccagcgaa tgcagcttgc cggcggagtc taggtagtcc
      121 atccgtgcat cgacgatctc gcaggtggtc gacgcctgtt cctgggtcgc caccaccttg
      181 tgcacatcca gcggcatgcc gtagcggtag ctttcggtcg gtaccggtgc ggcggcctgg
      241 gcggcgaacg cgggaagcgc aagcgcggcg agcagggtgg tggcgagcag ggtgcgagtc
      301 atgggggatc tcctggcggc aggaccgcgt cggtggaagg cgacatgcct tcgtcgaggc
      361 ctattccagg ccgcggagtt gtcccggatg tgtcgctgga atgcccgatt cgtcagccgc
      421 tgtatcgccg ctgccggccg atacatggcc gtacattcgc cgccccgctc ccgccggacg
      481 aatcgcgccc ggcgccatcc gtcgtctccc ccgttcgcga cagcgacaac cgggcttttt
      541 tgcacgcccc ggtattcgcc ccggctccgg atacagtgca atacaaaccc cggcaggcaa
      601 gcgccgcggg cgcggataca ctgcttgcaa gcacaccaac cgccacggga gccaggcaat
      661 ggagcatgtc gatcacatcc tgatcgtcga cgatgaccgc gagattcgcg agctggtagg
      721 caactacctg aagaagaacg gcctgcgcac caccatcgtc gccgatggcc ggcagatgcg
      781 cgcgttcctc gaagccaaca cggtggacct gatcgtcctc gacatcatga tgcccggcga
      841 cgacggcctg ctgctctgcc gcgagctgcg cgtcggcaag cacaaggcca cgccggtgct
      901 gatgctcacc gcgcgcaacg acgagaccga ccgcatcatc ggcctggaga tgggcgccga
      961 cgactacctg accaagccct tctccgcccg cgaactgctt gcccggatca acgccgtgct
     1021 gcggcgtacg cggatgctgc cgccgaacct caccgtgagc gagagcagcc ggctgatcgg
     1081 cttcggccag tggcaactgg acaccagcgc ccgccacctg ctcgacgacg ccggcaccgt
     1141 ggtcgccctc agcggcgccg agtaccgcct gctgcgggtg ttcctcgatc atccgcaacg
     1201 ggtactcagt cgcgaccagt tgctcaacct gacccagggc cgcgaggcgg acatcttcga
     1261 ccgttccatc gacctgctgg tcagccgcct gcgccaacgc ctcggcgacg acgcccgcga
     1321 accggagtac atcaagaccg tgcgcagcga gggctatgtg ttctcgctgc cggtgcgact
     1381 ggtcgaggcc catccatgaa gctcgccgtg ccgcgcccgc gcagcctcgc cgcgcgcctg
     1441 gcgctgatcc tcttcgccgg gctggtgctg gcctacgggc tgtccttcgc ctcgcagttc
     1501 tacgagcgct accagaccgc gaagcacatg atgctcgaca gcctcgaaca ggacgtggcg
     1561 atctcggtag ccatgctcga ccgcctgacg cccgccgagc gcgaggcctg gctgccgcgc
     1621 ctggaacgac gcacctaccg ctatcgcctc gacgccggcg agcccggcca gccgctggcg
     1681 ctggccgacg cgccggttgc cgcgcactcc atcgaacgcg ccctcgacgg tcaatacccg
     1741 ctgaccctgc gcacggtggc cgacagccgt ccgcacttcc aggtcctcct gcgcctgcgc
     1801 gacggcagcc cgctgaccat cgacgtcacg ccggccccgg tgccgctgtc cggctggctg
     1861 ccgctggtac tgctggtgca gttgctcctg ctgctgctct gcaccggcct cgcggtgcgc
     1921 accgccatcg gtccgctgac ccggctggtg aaggccgtgg aacatctcga tccgaatcgt
     1981 ccggcacagc ctctcgcgga aaccggccca cgcgaagtgg cgcatgcggc ggcggccttc
     2041 aatgccatgc aggcgcgcat cgccgactac ctcaaggagc gcatgcagtt gctcgcggcg
     2101 atttcccacg acctgcagac gccgatcacg cggatgaagc tgcgcgtcga gttcatggac
     2161 gcctccagcg acagggacaa gctgtggaac gatctcgaag agatgcagca cctggtccgc
     2221 gaaggcgtgg cctatgcccg cagcatgcac ggcagcaccg aaaccagttg ccgggtggac
     2281 ctcgacgcct tcctcgacag cctggtcttc gactaccagg acagcggcaa gcaggtacaa
     2341 ctcgacggcc gtaccggcgc ggtgatcgac acccgtccgc acgccctgcg ccgggtgctg
     2401 gtgaacctgg tcgacaatgc gctgaagttc gccggcgccg cgcgcctgga agtggaacgc
     2461 cgtaccgatg gcggcacgcg aatccaggtg ctggacaatg gcccggggat tcccgccgag
     2521 gaactcgacg aggtgctcaa gcccttctac cgggtggaaa actcgcgcaa tcgcgacacc
     2581 ggtggcaccg gcctcggcct ggccatcgcg cagcagctga gcctggccct cggcggccgc
     2641 ctgaccctgg ccaaccgcgc cggcggcggg ctttgcgcgc gcatcgagct ggacccctga
     2701 ggcgcccgta cagagcgata cataaccgcc ctcggcggac acactgcgga taaacccgct
     2761 tgcaacactc ctggccacgg gaagcggcgg cacatcgccg agccgctccc ggcaaccagg
     2821 agccccacca tgaccgtccc aacctctcaa tccgcctggc acggctggcg actgttcgcc
     2881 gtcctcgccg tcgccgtgct gtgcatgacc gccctcgtcc tggctctcca ggcgcaaccg
     2941 gtggagggcc tgcgcagcgc catccgcgcc accgcgcgca gttccttcgc gctgttcctc
     3001 gccgctttcc tcgcgtcctc gctggcgacc ctggtgcccg gcccggggac ccgcgcgctg
     3061 ctccgtgaaa ggcgctacct gggcctggcc ttcgccttct cccacgcagt acacgccttg
     3121 ctgatcctgg cctactggaa gctgttcccc gagacattct ggagcggccg ctcggtcgcg
     3181 gcgaacatcc ccggctcgat cggctacctg ttcatcctgc tgctcaccct cacctccttc
     3241 cgcaccccgg cccgactgct cggcccacgc gcctggaaag ccctgcactc gaccggcacc
     3301 tgggtgctgg cgggcatctt ctgcctgtcg ttcttcaaac gcatccccat gggcggctgg
     3361 tacgtactgg cgttcgccac gatcttctcc gccatcgtcc tcaagctcac cgccaagctc
     3421 gccgtgcgct tgcgtcgtcg cgacgtacag ccggcctgac ccatccaccg ccctcaacga
     3481 gacatcgatc atgcaagcat ccgacctgcg cgcctggcgc cgacccttcg ccctgctcga
     3541 ccgctgcggc ggctggagcg ccgacctgtc cctgcgactg ttcctggcct gggagttctt
     3601 cgagtccggt tgggaaaagt ggaacggcga gaactggttc ggcgatatcc agtcggcttt
     3661 cccctttccc ttcgaccgcc tgcccgccgc cttcaactgg gaactgtcgc tgtgggccga
     3721 actgctcggc gcgctgttcc tcctgctcgg cctcggtacc cgcctgaccg ccctggtgct
     3781 gatcgtcgtc accctggtgg cgaccgccgc cgtacactgg ccggcggagt ggtcgagcct
     3841 ggcggaactg gcccgcggct actcgatcac cgaccacggc ttcggcaatt tcaagctccc
     3901 ggcgatctac ctggcggcgc tgctgccgct gctgttggcg ggggcgggga agctgagcct
     3961 ggaccactgg ctcgggcggc gcctgggcct gtcccgctag gattcggcca gccacggaaa
     4021 aaccccggaa cgcgatcgcc tccgggggtt ttcacagcaa gccagaacca tcccacccac
     4081 cgcgtagggc gaatagcgcc aacggcgcta ttcgccgata caccggaccc accccggcgg
     4141 ataaccgcaa gcggttatcc gccctacacc aagaccgtcc cacccaccac gtagggcgga
     4201 tagcgccaaa ggcgctatcc gccgatgcat cgactccaca agggctgcgt cgtcatccgc
     4261 ccgcccaatc gcgttccagg gttccgagca cgacaccctg ggtccgcaac gctgccagca
     4321 actccagccc cgccgcgtcg agcgctccgg gcgcactccg cgcctcgagc gccagcgccg
     4381 ccaggtgctc gcgcccgctc aggcgccgtc tcgccagcga ctccagcagg cggcaggcca
     4441 gcggagtcag gcgcgcggta tgcacgcgat gcgaggaatc gcggtgcatc aacagcaggg
     4501 tcggttccgc aggcgcttcg gcgagcgcga cgtcctcttc gagccgatgc accggccagc
     4561 gatagcccag cggcagcgcc aggctcgaca gcagcggcac cccgtcgagc aggtcgcctt
     4621 cacgccgata cggcggatcg tcgggctcgg ccaggtagag gcgcgtttcg ctccattcga
     4681 agtgggccaa ctcggcttgc cacgccggcc gatactcgcc ccgctgccgc aggtagtcga
     4741 cgaagacccc ggcgatacgg gtgaacaggg gggtatggct tctctcctcg cgatagaact
     4801 cgcgcaccag gccatgccac tgctgctcgc caagcagccc gcgcaagcgc gggaagccgc
     4861 tggcaaggag gccttcgatg gcgttgtaga acagctcgcg gtagacccgc aggcgacgtt
     4921 cttcgatgtc cggcggcggc gcattgccaa gcgggtcgcg caggtgccgg gcgaggctga
     4981 actgctgttg gcgcaggcgc tcatccatga cggcgtccct cgtcgcgttg ccattggcgg
     5041 atctgctcca cttccagcag cagttcgccc agcggcggat agttgaagtc ccgctcgagc
     5101 agggtcgggc gcacgccgaa gcgacgatag gcggctccga gcaaggccca gacgccgggc
     5161 ttcacggcgg caccatgggt gtcgatcttc aggtccggcg cctcgtcgta gtgccccgcc
     5221 acatggtagg cggcgacccg cccgggcggc agccggacga ggaagtcgag ggcgtcgtag
     5281 ccgtggttgc aggcgttgac gaacaggttg ttgacgtcca gcaacaggtc gcagtcggcc
     5341 tcgtcgagta ccgcgttgac gaactcgatc tcgctcatct cccggtacgg cgctgcatag
     5401 taggaaatgt tctccaccgc gatgcgccgc tccaggcgct cctgcgcctc gcggatgcgc
     5461 gccgcgacgt gacgcaccgc ggcctcggtg aacggcagcg gcaacagatc atagagatgg
     5521 ccatcgtcgg aacagtagct gaggtgctcg ctgtacaacg cgacccggtg gcggacgagg
     5581 aagcgtcggg tctgctcgat aaaggcggca tccagcggcg tggagccgcc gagggacagc
     5641 gagagaccgt gacaggtcag tggaatgcgc tccaccaggc gctccaggtc ggcaccgaag
     5701 gcaccgccga cgccgatcca gttgtccggc gcgcattcga ggaagtccac cgcgccgggc
     5761 gccatcgcca gcagttgcgg aagcaggccg cgcctcaggc cgaggccggc ggcgttgtcg
     5821 atcagggtca tgggatagct ccggaaacgg cgacgccccc gctttcccag gggaaagaga
     5881 gggcgccgcc agggtgtgga aaggctcagt gctggccttg ctccagcttg ctgaacagcc
     5941 cggcgggcat cggcttgccg ttggcctcgt aggtcttgcg caggtgttcg taggcctcgg
     6001 cttcggaaat gaagccgtca tggtcgctat cgatgctgtc gaactcaccg gcacggtcct
     6061 tggccaccgc gaggaactcg gcgcgcgaga ccttgccatc gtgatcggtg tcggttcggg
     6121 caaaggaggc gtcgccgcac ttgccctccc cgcacttgcc ctcggcgccg gccttggccg
     6181 gggtcttcgc ggagccgccg ctaccacact tgccttctcc gcacttgcct tcgccggcgc
     6241 tcgccgccgc cacttgcagc ccctggccca gcggctcgac ggcgaacgcc gaaccgccga
     6301 gcagcattcc ccccaccagt acggcaccga gcaggctggc ggaagtcttt tgacgcgaat
     6361 cgaaaacgga catgcttctt ctccacagta aacgcggccg ggccgcaggc gcggcgctgg
     6421 tgggcgccgg tacgaaccgg gcggcgggac cttctggggt cgtcccgggc gccgcggttc
     6481 ggatgtggcc atttcgcctg ggagatgtat cgggggtgta tcgcccgaca cgtggatttg
     6541 tacgccggag gtatcgaaac cgcgcatgga tacaaagcga tacgcaatcg agcgcgggca
     6601 tgccgacgaa gtgccgggca tctctcactc ccgccggccc atctcggcta ccgttaggag
     6661 acagccacct ggcccagtct cgaggtcgag cccatcgtgc tgaaacgcat tccggtaacc
     6721 cagcttcgcc tcggtatgtt cgtccagagc ctttgcggct cgtggctgga ccacccgttc
     6781 tggaaaagag gtggcttcct gctcgacagc caggccgacc tgcagcgcct gcgcgaaagc
     6841 gccgtgaagg aggtctggat cgatgccagc aagggcctcg acctcccgga ggaagcggcg
     6901 gtctcggccg ctgcggtcct gccggtcacc atgccggccg gcccttcgcc ggcgcgggtc
     6961 gccctggagg aggaaatccg ccacgccgcc ctgctctgca gccgtgccaa ggccgccgtg
     7021 gtcagcatgt tccgcgacgc gcgcatgggc caggccatcg ataccgcgca tgcatcggac
     7081 ctggtggacg aaatctccgc ctcggtgctg cgccatccca acgcgctgct cagcctggta
     7141 cggctgaaga cctcggatga atacacctac atgcattcgg tggcggtctg tgcgctgatg
     7201 atcgccctcg cccgccagct cgaactgccc gacccgctgg tacgcgaggc ggggctggcc
     7261 ggactgctgc acgacatcgg caagatggcg gtgcccgatc cgatcctgaa caagcccggc
     7321 aagctcaccg acccggagtt cggcctggtt cgccggcatc cgcagaacgg cgcgcggatg
     7381 ctgctcgatt gccgccaggt cagcgccctg gtggtggatg tctgcctgca ccaccacgag
     7441 cgcatcgacg gcaccggcta ccccttcggc ctggcgcagg agcagatcag cctgctggcg
     7501 cgaatgggcg cggtgtgcga cgtctacgac gcgatcacct ccgaccgtcc ctacaagaag
     7561 ggctggaacg ccgccgaggc gatccgacgc atggccgaat ggaacgggca cttcgacccg
     7621 caggtgttcc gcgccttcgt caaggcggtg ggcatctacc cggtcggcgc gctggtcagg
     7681 ctggaaagcg ggcgcctcgg cgtggtcctc gaacaacacg gccgctcgct gctgacgcca
     7741 cgggtcaagg tattcttctc ggcccgctcg aaggtgccga tcccgcagca ggtggtagac
     7801 ctgggtaggg ccggacagac cgaccgaatc gtcggcttcg agccggcgga agcctggaac
     7861 ttccgcaatc tcgacgagat gtggacggga ctggccaagt ccacgggctc ttatttcgac
     7921 gcgggaaccg gaaatccgta gacgccttcc gcccgcaagc cgagcaccgc tcccgtaggg
     7981 cgcataacgc gaagcgttat ccgccgtttc gccgcaatct ccgcctgctc cgcgttgctt
     8041 taagcgcacc atcgtcgata ctgctggcaa tccgccgaca gttttcaaga ggccatatga
     8101 gtccgctcct ggagacaatc gaagagcaca gcagaaatgg ctgtgctcca tccaaagcgt
     8161 tgattgccct gtggtccgca ggcgccgacc tgagggtttc cccgaggaag gctggccgcc
     8221 tatgcgaact tgccgtcgtt gccgcagcag ggaaagcagg catgctcgag agcgagatcg
     8281 ttgcggcacg ccgggcctat gccgccagcc tgggagtgac gcttagcgga gcgatcagca
     8341 acgccgacga gccggtccat atccgccacg ccgtcagcaa ttccaatcac aaccccaacg
     8401 cctcaaaccg tatcaacctt gggagggccc gagcgtataa aaaaaggcgc gaggaaggtg
     8461 attacttctt catcgacact tgaatcgcct gcataaccgt tatctccccc gcgcctcaac
     8521 ggcagccatc tccagcaacc acccccggaa cgccagcatc gcgctggtct ccccccgcga
     8581 ctgcaagcgc gtcagccagt agctgccggt actcacttcg gtggcgaacg gacgccggat
     8641 gctctcgctg gccagttgcc gggcaaacat cgccgccggc gccagggcca cgccgacacc
     8701 ctggcgggcc gcctcgagca tggccagcga ggtgtcgaag acgatgctcc gggtcagtgg
     8761 cgcgtgcgcc ggcagtccgg ccgcctggaa ccacagcggc cactcgtcgg cgcggtagga
     8821 gcgcagcagg gtgtgctgca gcaggtcggc gggactgtgc aactgggcgg cgacctccgg
     8881 gcagcagagc accgtcagcg gcgcctcgaa caacgccagc gcctcggtgc cgtgccaggc
     8941 gccgccgccg aagcggatcg cgtagtcgag cccctcggcg gcgatgtcga cgcggttgtt
     9001 gtgggtggac aggcgcagat cgatgaaggg atggcgcgcc tggaagtcct ccagccgcgg
     9061 cagcagccaa ccgaccgtga aggttccgac cgcgccgacg gtgagcacgt cccggtagtg
     9121 gccaccctcg aaacgttcca gcaggccggc gatgcggtcg aaggagtcac acagcaccgg
     9181 cagcaggctc tcgccctcgt gggtcagcat gaggccgcgc ggcagacgct tgaacagggc
     9241 cacgccgaga cgctcctcga ggctcttcac ctggtggctg accgccgcct gggtcacgca
     9301 cagctcgatg gccgcgcggg tgaagctcag gtgccgggcc gaagcttcga aggcgcgcag
     9361 ggcgttcagc ggcaaatggg gtcgaaccaa tctctgctcc aaatttttct aatggctgcc
     9421 gcgagtattc gtcgtttgcc gcaaatcctg cgcaagccta gattttcccc gcccgccgat
     9481 caaggagcgc tcccggggcg gtttctcatg cagccaacga caaaggacgc caatcctcat
     9541 gcgcgatacc agattcccct gcctgtgcgg catcgccgct tccacactgc tgttcgccac
     9601 caccccggcc attgccggcg aggccccggc ggatcgcctg aaggcactgg tcgacgccgc
     9661 cgtacaaccg gtgatgaagg ccaatgacat tccgggcctg gccgtagcca tcagcctgaa
     9721 aggagaaccg cattacttca gctatgggct ggcctcgaaa gaggacggcc gccgggtgac
     9781 gccggagacc ctgttcgaga tcggctcggt gagcaagacc ttcaccgcca ccctcgccgg
     9841 ctatgccctg acccaggaca agatgcgcct cgacgaccgc gccagccagc actggccggc
     9901 actgcagggc agccgcttcg acggcatcag cctgctcgac ctcgcgacct ataccgccgg
     9961 cggcttgccg ctgcagttcc ccgactcggt gcagaaggac caggcacaga tccgcgacta
    10021 ctaccgccag tggcagccga cctacgcgcc gggcagccag cgcctctatt ccaacccgag
    10081 catcggcctg ttcggctatc tcgccgcgcg cagcctgggc cagccgttcg aacggctcat
    10141 ggagcagcaa gtgttcccgg cactgggcct cgaacagacc cacctcgacg tgcccgaggc
    10201 ggcgctggcg cagtacgccc agggctatgg caaggacgac cgcccgctac gggtcggtcc
    10261 cggcccgctg gatgccgaag gctacggggt gaagaccagc gcggccgacc tgctgcgctt
    10321 cgtcgatgcc aacctgcatc cggagcgcct ggacaggccc tgggcgcagg cgctcgatgc
    10381 cacccatcgc ggttactaca aggtcggcga catgacccag ggcctgggct gggaagccta
    10441 cgactggccg atctccctga agcgcctgca ggccggcaac tcgacgccga tggcgctgca
    10501 accgcacagg atcgccaggc tgcccgcgcc acaggcgctg gagggccagc gcctgctgaa
    10561 caagaccggt tccaccaacg gcttcggcgc ctacgtggcg ttcgtcccgg gccgcgacct
    10621 gggcctggtg atcctggcca accgcaacta tcccaatgcc gagcgggtga agatcgccta
    10681 cgccatcctc agcggcctgg agcagcaggg caaggtgccg ctgaagcgct gaagcgcgct
    10741 cgcgagggcg acggagcgta gcggcgcggg acgccggtcc tggctatgat ggtgccatga
    10801 gcgcttcccc gcccctccgc cagccctgcc c
//
