LOCUS       NC_002516.2            14761 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_002516.2 Pseudomonas aeruginosa PAO1, complete genome.
ACCESSION   NC_002516
VERSION     NC_002516.2
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:42:12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3860896
            Orig. end    :: 3875657
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14761
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[3865896:3870657]"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9761
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     cand_cluster    1..14761
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14761
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="10"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     CDS             1413..3377
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103:FAD dependent oxidoreductase (Score: 129.3;
                     E-value: 3.4e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3537"
                     /transl_table=11
                     /translation="MSDFQHAQLDWDENGQPLSRAFGDVYFSRHSGLNETRHVFLATNR
                     LAERFAALGDGEVLCIGETGFGTGLNFLCAWQLFERVAPAGARLEFVSVEKFPLAAADL
                     RRALALWPELAPWSEALLGQYLAVHPGFQRLAFAGGRVGLTLLLGDALECLPQLDARVD
                     AWFLDGFAPAKNPDMWSPVLFAELARLSAPQATLGTFTSAGFVRRGLVEAGFAMQRVPG
                     YGQKREMLSGTYQGPPANAGKPWYARPAPHAGRRAALVVGGGLAGCASAASLAARGWQV
                     TLIERHPGLAREASGNPQGVLYLKLSAHGTPLSRLVLSGFGHTRRLLERLRRGHDWDAC
                     GVLQLAFDAKEAQRQAQLAAAFPADLLHGLEREQAERLAGVALPAGGLFYPEAGWVHPP
                     ALCQALAATPGITLLSGRAVRLRREGDDWCAYAGDECLARAPLAILATAADIRDFPPAA
                     ELPLKRIRGQVTRLPATPQSRALRTVVCAEGYVAPPRGDEHTLGASFDFKSEDLAPTLA
                     EHQGNLELLREISPDLLQRLGADDLPLERLEGRAAFRCTSPDYLPLVGPLAERAAFDEA
                     YAVLARDARQVPERACPWLPGLYLNSGHGSRGLISAPLSGELLAAWICGEPLPLPRAVA
                     EACHPNRFLLRDLVRGQRG"
     PFAM_domain     1746..2114
                     /aSDomain="Methyltransf_30"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05430.13"
                     /description="S-adenosyl-L-methionine-dependent
                     methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3537_0391"
                     /evalue="7.70E-45"
                     /label="ctg1_3537"
                     /locus_tag="ctg1_3537"
                     /protein_end="234"
                     /protein_start="111"
                     /score="151.9"
                     /tool="antismash"
                     /translation="PELAPWSEALLGQYLAVHPGFQRLAFAGGRVGLTLLLGDALECLP
                     QLDARVDAWFLDGFAPAKNPDMWSPVLFAELARLSAPQATLGTFTSAGFVRRGLVEAGF
                     AMQRVPGYGQKREMLSGTY"
     aSDomain        2184..3365
                     /aSDomain="TIGR03197"
                     /aSTool="tigrfam"
                     /description="MnmC_Cterm: tRNA U-34
                     5-methylaminomethyl-2-thiouridine biosynthesis protein
                     MnmC, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3537_0079"
                     /evalue="2.20E-135"
                     /identifier="TIGR03197"
                     /label="ctg1_3537"
                     /locus_tag="ctg1_3537"
                     /protein_end="651"
                     /protein_start="257"
                     /score="449.7"
                     /tool="antismash"
                     /translation="ALVVGGGLAGCASAASLAARGWQVTLIERHPGLAREASGNPQGVL
                     YLKLSAHGTPLSRLVLSGFGHTRRLLERLRRGHDWDACGVLQLAFDAKEAQRQAQLAAA
                     FPADLLHGLEREQAERLAGVALPAGGLFYPEAGWVHPPALCQALAATPGITLLSGRAVR
                     LRREGDDWCAYAGDECLARAPLAILATAADIRDFPPAAELPLKRIRGQVTRLPATPQSR
                     ALRTVVCAEGYVAPPRGDEHTLGASFDFKSEDLAPTLAEHQGNLELLREISPDLLQRLG
                     ADDLPLERLEGRAAFRCTSPDYLPLVGPLAERAAFDEAYAVLARDARQVPERACPWLPG
                     LYLNSGHGSRGLISAPLSGELLAAWICGEPLPLPRAVAEACHPNRFLLRDLVRG"
     PFAM_domain     2187..3278
                     /aSDomain="DAO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01266.26"
                     /description="FAD dependent oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3537_0392"
                     /evalue="4.60E-50"
                     /label="ctg1_3537"
                     /locus_tag="ctg1_3537"
                     /protein_end="622"
                     /protein_start="258"
                     /score="171.3"
                     /tool="antismash"
                     /translation="LVVGGGLAGCASAASLAARGWQVTLIERHPGLAREASGNPQGVLY
                     LKLSAHGTPLSRLVLSGFGHTRRLLERLRRGHDWDACGVLQLAFDAKEAQRQAQLAAAF
                     PADLLHGLEREQAERLAGVALPAGGLFYPEAGWVHPPALCQALAATPGITLLSGRAVRL
                     RREGDDWCAYAGDECLARAPLAILATAADIRDFPPAAELPLKRIRGQVTRLPATPQSRA
                     LRTVVCAEGYVAPPRGDEHTLGASFDFKSEDLAPTLAEHQGNLELLREISPDLLQRLGA
                     DDLPLERLEGRAAFRCTSPDYLPLVGPLAERAAFDEAYAVLARDARQVPERACPWLPGL
                     YLNSGHGSRGLISAPLSGELLAAW"
     CDS             3478..4230
                     /locus_tag="ctg1_3538"
                     /transl_table=11
                     /translation="MDVLLFESLGIGAILGLLLGLTGAGGSLVALPLLLSLHLPLRDAI
                     GVSLGAVALSALIGAIPRARQGQVAWRPVLVLALAGLPSNAVGQWLGRFVPEGVLIVAF
                     CLLVLWSAWRMWRGAGMKREASDQARSLPLLGIGLAVGLLSGLMGVGGGFLVVPGLLWF
                     TPLSMMAATATSMAVIALVSGGGFLIYLTGAHPPLPLLGGLAAGGAVGVLGGNLLAQRL
                     GGPTLQRLFALMLVAVSFSLAAQKLYGG"
     PFAM_domain     3502..4200
                     /aSDomain="TauE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01925.21"
                     /description="Sulfite exporter TauE/SafE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3538_0393"
                     /evalue="5.40E-41"
                     /label="ctg1_3538"
                     /locus_tag="ctg1_3538"
                     /protein_end="241"
                     /protein_start="8"
                     /score="140.9"
                     /tool="antismash"
                     /translation="LGIGAILGLLLGLTGAGGSLVALPLLLSLHLPLRDAIGVSLGAVA
                     LSALIGAIPRARQGQVAWRPVLVLALAGLPSNAVGQWLGRFVPEGVLIVAFCLLVLWSA
                     WRMWRGAGMKREASDQARSLPLLGIGLAVGLLSGLMGVGGGFLVVPGLLWFTPLSMMAA
                     TATSMAVIALVSGGGFLIYLTGAHPPLPLLGGLAAGGAVGVLGGNLLAQRLGGPTLQRL
                     FALMLVAVSFS"
     CDS             complement(4385..4858)
                     /gene_functions="regulatory (smcogs) SMCOG1135:MarR family
                     transcriptional regulator (Score: 79.5; E-value: 2.9e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3539"
                     /transl_table=11
                     /translation="MVESNKTAADTYSLAIFRAIRRLQQAAEIHSKRLSRYGGLTPLQL
                     LILHVLAVEGELTATQLAKLVSLSQASLSGVLDRLEGRGLLYRRRDEQDRRKSWLHLDP
                     AGHEALAEAPPLLPEYVIERFAALPEWERHGLLAALLRAADLFGLPEEDVEEE"
     PFAM_domain     complement(4568..4741)
                     /aSDomain="MarR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01047.24"
                     /description="MarR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3539_0394"
                     /evalue="1.60E-16"
                     /label="ctg1_3539"
                     /locus_tag="ctg1_3539"
                     /protein_end="97"
                     /protein_start="39"
                     /score="60.0"
                     /tool="antismash"
                     /translation="LTPLQLLILHVLAVEGELTATQLAKLVSLSQASLSGVLDRLEGRG
                     LLYRRRDEQDRRK"
     aSDomain        5001..6758
                     /aSDomain="TIGR03104"
                     /aSTool="tigrfam"
                     /description="trio_amidotrans: asparagine synthase family
                     amidotransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3540_0080"
                     /evalue="0.00E+00"
                     /identifier="TIGR03104"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="586"
                     /protein_start="0"
                     /score="1018.9"
                     /tool="antismash"
                     /translation="MCGISGEFRFDNQAADLAAVERITHHLAPRGPDAWGFHAQGPIAL
                     GHRRLKIMDLAEASGQPMIDPDLGLAMVFNGAIYNYPELRGELESLGYRFFSGGDTEVL
                     LKGYHAWGADLLPRLNGMFAFAVWERDRQRLFLARDRLGIKPLYYSLDRSRLRFASSLP
                     ALLKGGDIASDLDPQALNFYLNFHAVVPAPHTLLEGVKKLPPATWMSVDLDGSCEQRTW
                     WTLDYGPRPDERELTLDDWQERVLDGLREAVAIRQRAAREVGVLLSGGVDSSLLVGLLH
                     EAGVDNLLTFSIGFEDAGGERGDEFQYSDLIAERYHTRHHRLRIGEHEVIEQLPAAFRA
                     MSEPMVSHDCIAFYLLAREVSKHCKVVQSGQGADELFAGYHWYPKVDGADDAFAAYRAA
                     FFDRDHEEYLATVGERFRVEDVAGRFVRDHFASPGAEAAVDKALRLDSTIMLVDDPVKR
                     VDNMTMAWGLEARVPFLDYRLAELSARIPARFKLGDGGKQVLKGAARKVIPSEVIDRPK
                     GYFPVPGLKHLQGRTREWVRELLLDPSQDRGLFQPAIFDRLLSDPDGDLTPLRGSKLWQ
                     LAALNLWLSE"
     CDS             5001..6770
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 593.5; E-value: 8e-180)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3540"
                     /sec_met_domain="Asn_synthase (E-value: 5.6e-81, bitscore:
                     271.3, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.1e-43, bitscore:
                     146.5, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03104 (E-value: 0.0, bitscore: 1018.9,
                     seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGISGEFRFDNQAADLAAVERITHHLAPRGPDAWGFHAQGPIAL
                     GHRRLKIMDLAEASGQPMIDPDLGLAMVFNGAIYNYPELRGELESLGYRFFSGGDTEVL
                     LKGYHAWGADLLPRLNGMFAFAVWERDRQRLFLARDRLGIKPLYYSLDRSRLRFASSLP
                     ALLKGGDIASDLDPQALNFYLNFHAVVPAPHTLLEGVKKLPPATWMSVDLDGSCEQRTW
                     WTLDYGPRPDERELTLDDWQERVLDGLREAVAIRQRAAREVGVLLSGGVDSSLLVGLLH
                     EAGVDNLLTFSIGFEDAGGERGDEFQYSDLIAERYHTRHHRLRIGEHEVIEQLPAAFRA
                     MSEPMVSHDCIAFYLLAREVSKHCKVVQSGQGADELFAGYHWYPKVDGADDAFAAYRAA
                     FFDRDHEEYLATVGERFRVEDVAGRFVRDHFASPGAEAAVDKALRLDSTIMLVDDPVKR
                     VDNMTMAWGLEARVPFLDYRLAELSARIPARFKLGDGGKQVLKGAARKVIPSEVIDRPK
                     GYFPVPGLKHLQGRTREWVRELLLDPSQDRGLFQPAIFDRLLSDPDGDLTPLRGSKLWQ
                     LAALNLWLSEQGL"
     aSDomain        5004..6557
                     /aSDomain="TIGR01536"
                     /aSTool="tigrfam"
                     /description="asn_synth_AEB: asparagine synthase
                     (glutamine-hydrolyzing)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3540_0081"
                     /evalue="2.60E-118"
                     /identifier="TIGR01536"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="519"
                     /protein_start="1"
                     /score="394.2"
                     /tool="antismash"
                     /translation="CGISGEFRFDNQAADLAAVERITHHLAPRGPDAWGFHAQGPIALG
                     HRRLKIMDLAEASGQPMIDPDLGLAMVFNGAIYNYPELRGELESLGYRFFSGGDTEVLL
                     KGYHAWGADLLPRLNGMFAFAVWERDRQRLFLARDRLGIKPLYYSLDRSRLRFASSLPA
                     LLKGGDIASDLDPQALNFYLNFHAVVPAPHTLLEGVKKLPPATWMSVDLDGSCEQRTWW
                     TLDYGPRPDERELTLDDWQERVLDGLREAVAIRQRAAREVGVLLSGGVDSSLLVGLLHE
                     AGVDNLLTFSIGFEDAGGERGDEFQYSDLIAERYHTRHHRLRIGEHEVIEQLPAAFRAM
                     SEPMVSHDCIAFYLLAREVSKHCKVVQSGQGADELFAGYHWYPKVDGADDAFAAYRAAF
                     FDRDHEEYLATVGERFRVEDVAGRFVRDHFASPGAEAAVDKALRLDSTIMLVDDPVKRV
                     DNMTMAWGLEARVPFLDYRLAELSARIPARFKLGDGGKQVLKGAARKVIPSEVIDRPKG
                     Y"
     PFAM_domain     5139..5498
                     /aSDomain="GATase_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13537.8"
                     /description="Glutamine amidotransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3540_0395"
                     /evalue="7.30E-43"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="166"
                     /protein_start="46"
                     /score="145.5"
                     /tool="antismash"
                     /translation="HRRLKIMDLAEASGQPMIDPDLGLAMVFNGAIYNYPELRGELESL
                     GYRFFSGGDTEVLLKGYHAWGADLLPRLNGMFAFAVWERDRQRLFLARDRLGIKPLYYS
                     LDRSRLRFASSLPALL"
     misc_feature    5343..5345
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     PFAM_domain     5736..6752
                     /aSDomain="Asn_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00733.23"
                     /description="Asparagine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3540_0396"
                     /evalue="1.90E-80"
                     /label="ctg1_3540"
                     /locus_tag="ctg1_3540"
                     /protein_end="584"
                     /protein_start="245"
                     /score="271.3"
                     /tool="antismash"
                     /translation="LDGLREAVAIRQRAAREVGVLLSGGVDSSLLVGLLHEAGVDNLLT
                     FSIGFEDAGGERGDEFQYSDLIAERYHTRHHRLRIGEHEVIEQLPAAFRAMSEPMVSHD
                     CIAFYLLAREVSKHCKVVQSGQGADELFAGYHWYPKVDGADDAFAAYRAAFFDRDHEEY
                     LATVGERFRVEDVAGRFVRDHFASPGAEAAVDKALRLDSTIMLVDDPVKRVDNMTMAWG
                     LEARVPFLDYRLAELSARIPARFKLGDGGKQVLKGAARKVIPSEVIDRPKGYFPVPGLK
                     HLQGRTREWVRELLLDPSQDRGLFQPAIFDRLLSDPDGDLTPLRGSKLWQLAALNLWL"
     CDS             6811..8568
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3541"
                     /sec_met_domain="RimK (E-value: 1.5e-08, bitscore: 32.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03103 (E-value: 5.5e-274, bitscore:
                     908.0, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGHLHLPHPHNQRLQRIQAPTYERLQARLAEDHSEPTEKPLSIH
                     CGWGRLLIGQTYPDAEELARDLLQEAPGERDIALYVAAPQQVLAHAPQQLFLDPSDTLR
                     LWFTDYRPARRPPRGFRIRRVHTEEDWAAINRLYLARGMLPVQTERLSPRHQGGPIYWL
                     AEDADTGVAVGTVMGLNHAKAFQDPEGGSSLWCLAVDPQCSRPGVGEALVRHLVEHFMS
                     RELAYLDLSVLHNNQQAKALYRKLGFRELATFTIKRKNGINQSLFLGPGPEEDLNPYAR
                     IIVDEAHRRGIEVRVDDAEGGLFTLTQGGRQIRCRESLSDLTTAVSMTLCQDKVLTHRA
                     LQHAGLRQPQQRLAGSAEENAAFLAEHGSLVVKPVDGEQGQGVAVDLRTAEEVEEAIEA
                     ARHFDSRVLLESYHAGHDLRVLVIGYEVVAAAIRRPAAVIGDGRHSIRELIEAQSRRRQ
                     AATGGESRIPLDHETERTLRAAGYGYDDVLPSGEHLAVRRTANLHTGGILEDVTDALHP
                     ALREAAIQAARALEIPVVGLDFLVEAADQPDYVIIEANERAGLANHEPQPTAERFVDLL
                     FPLSREVPS"
     aSDomain        6928..8556
                     /aSDomain="TIGR03103"
                     /aSTool="tigrfam"
                     /description="trio_acet_GNAT: GNAT-family acetyltransferase
                     TIGR03103"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3541_0082"
                     /evalue="4.40E-274"
                     /identifier="TIGR03103"
                     /label="ctg1_3541"
                     /locus_tag="ctg1_3541"
                     /protein_end="582"
                     /protein_start="39"
                     /score="908.0"
                     /tool="antismash"
                     /translation="KPLSIHCGWGRLLIGQTYPDAEELARDLLQEAPGERDIALYVAAP
                     QQVLAHAPQQLFLDPSDTLRLWFTDYRPARRPPRGFRIRRVHTEEDWAAINRLYLARGM
                     LPVQTERLSPRHQGGPIYWLAEDADTGVAVGTVMGLNHAKAFQDPEGGSSLWCLAVDPQ
                     CSRPGVGEALVRHLVEHFMSRELAYLDLSVLHNNQQAKALYRKLGFRELATFTIKRKNG
                     INQSLFLGPGPEEDLNPYARIIVDEAHRRGIEVRVDDAEGGLFTLTQGGRQIRCRESLS
                     DLTTAVSMTLCQDKVLTHRALQHAGLRQPQQRLAGSAEENAAFLAEHGSLVVKPVDGEQ
                     GQGVAVDLRTAEEVEEAIEAARHFDSRVLLESYHAGHDLRVLVIGYEVVAAAIRRPAAV
                     IGDGRHSIRELIEAQSRRRQAATGGESRIPLDHETERTLRAAGYGYDDVLPSGEHLAVR
                     RTANLHTGGILEDVTDALHPALREAAIQAARALEIPVVGLDFLVEAADQPDYVIIEANE
                     RAGLANHEPQPTAERFVDLLFPLSRE"
     PFAM_domain     7282..7554
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3541_0397"
                     /evalue="7.30E-11"
                     /label="ctg1_3541"
                     /locus_tag="ctg1_3541"
                     /protein_end="248"
                     /protein_start="157"
                     /score="42.4"
                     /tool="antismash"
                     /translation="GPIYWLAEDADTGVAVGTVMGLNHAKAFQDPEGGSSLWCLAVDPQ
                     CSRPGVGEALVRHLVEHFMSRELAYLDLSVLHNNQQAKALYRKLGF"
     PFAM_domain     7804..8112
                     /aSDomain="RimK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08443.13"
                     /description="RimK-like ATP-grasp domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3541_0398"
                     /evalue="5.10E-08"
                     /label="ctg1_3541"
                     /locus_tag="ctg1_3541"
                     /protein_end="434"
                     /protein_start="331"
                     /score="32.8"
                     /tool="antismash"
                     /translation="QDKVLTHRALQHAGLRQPQQRLAGSAEENAAFLAEHGSLVVKPVD
                     GEQGQGVAVDLRTAEEVEEAIEAARHFDSRVLLESYHAGHDLRVLVIGYEVVAAAIRR"
     CDS             8565..9761
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3542"
                     /sec_met_domain="TIGR03106 (E-value: 2.2e-171, bitscore:
                     567.6, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 3e-74, bitscore:
                     248.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPLPQPDLNYLQRVLLEMLAIPSPTGFTDTIVRYVAEQLDELGV
                     PFEMTRRGTIRATLQGRLNTPDRAVSAHLDTIGALVREIKPNGRLGLAPVGCWSSRFAE
                     GSRVTVFTEQGVFRGSVLPLLASGHAFNTEVDNLKISWDNIELRLDAYTASRADSESLG
                     ISVGDYVAFDPLPEFTESGHISARHLDDKAGVAALLAALKAVKESGQEPPIDCHPLFTI
                     TEEVGSGAAGALPWDVSEFVGIDIAPVAEGQNSNEHSVSVAMQDSGGPYDFHLSRHLLR
                     LGERHDIALRRDLFRYYHSDAQSAIAAGHDTRAALLAFGCDATHGYERTHIDSLAALSR
                     LLTAYILSPPVFASDAKPRETSLERFNKQLEHPVHMESCTHVPPVDEVLDSSNNSDKG"
     aSDomain        8586..9611
                     /aSDomain="TIGR03106"
                     /aSTool="tigrfam"
                     /description="trio_M42_hydro: hydrolase, peptidase M42
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_3542_0083"
                     /evalue="1.80E-171"
                     /identifier="TIGR03106"
                     /label="ctg1_3542"
                     /locus_tag="ctg1_3542"
                     /protein_end="349"
                     /protein_start="7"
                     /score="567.6"
                     /tool="antismash"
                     /translation="DLNYLQRVLLEMLAIPSPTGFTDTIVRYVAEQLDELGVPFEMTRR
                     GTIRATLQGRLNTPDRAVSAHLDTIGALVREIKPNGRLGLAPVGCWSSRFAEGSRVTVF
                     TEQGVFRGSVLPLLASGHAFNTEVDNLKISWDNIELRLDAYTASRADSESLGISVGDYV
                     AFDPLPEFTESGHISARHLDDKAGVAALLAALKAVKESGQEPPIDCHPLFTITEEVGSG
                     AAGALPWDVSEFVGIDIAPVAEGQNSNEHSVSVAMQDSGGPYDFHLSRHLLRLGERHDI
                     ALRRDLFRYYHSDAQSAIAAGHDTRAALLAFGCDATHGYERTHIDSLAALSRLLTAYIL
                     SP"
     PFAM_domain     8721..9587
                     /aSDomain="Peptidase_M42"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05343.16"
                     /description="M42 glutamyl aminopeptidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3542_0399"
                     /evalue="5.30E-74"
                     /label="ctg1_3542"
                     /locus_tag="ctg1_3542"
                     /protein_end="341"
                     /protein_start="52"
                     /score="248.9"
                     /tool="antismash"
                     /translation="GTIRATLQGRLNTPDRAVSAHLDTIGALVREIKPNGRLGLAPVGC
                     WSSRFAEGSRVTVFTEQGVFRGSVLPLLASGHAFNTEVDNLKISWDNIELRLDAYTASR
                     ADSESLGISVGDYVAFDPLPEFTESGHISARHLDDKAGVAALLAALKAVKESGQEPPID
                     CHPLFTITEEVGSGAAGALPWDVSEFVGIDIAPVAEGQNSNEHSVSVAMQDSGGPYDFH
                     LSRHLLRLGERHDIALRRDLFRYYHSDAQSAIAAGHDTRAALLAFGCDATHGYERTHID
                     SLAALSRL"
     CDS             9899..12658
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 84.2; E-value: 1.7e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_3543"
                     /transl_table=11
                     /translation="MSRLCLVLLLLCCALPARAQPPAPLDGEDLRLSLGAYAEYYRDAG
                     GKARLGDILALPAQAFAALRGDHANFGKNAAAWWFRVRLDNRNGADLAGFLEVNYPLLD
                     DLKVYLLTADGRIEQQESGDLFAFSQRPVQVRNFWFPLRLPPGESTLLLRVQSTSTVYL
                     PLYFSTYAASAASQETLMGFNGAFYGVLFGLFCYNLFLFVSLREATYAWYLLYNLSLGL
                     FSASFDGLLFKLLPGHVALESAGIYLLMYLSCLVSIQFSRGYLYTRRDFPRLDRFLRGL
                     LLACVVLLASEPLVGLRAWNVLASLTVMLVSLSLLLAGVHVWRQGLRYGLYYILAWGAL
                     LLSFLVTTAASLGFELFGLFGSSVVKIGMTVELVTLSIGLADRINALKEEGFRSRQAAE
                     QARVENEAKSRFLAKMSHEIRTPLNGVLGMLQLLRDTPLDRGQAAYVETIASSGSALMS
                     VINDILDYARIESGKLHLERIDFDLEELLSDTLALFSAQAVEKRLHLHLGLDRGVPRRL
                     NGDPTRLRQVLMNLLSNALKFTAEGHVAVRVQRRFDEGGRERLLYSVSDSGIGISAQAQ
                     KTLFESFSQADSSTTRRYGGSGLGLAISRELVQMMGGRIEVSSEPGKGTRFSVDLPLSP
                     ALDAGEADELAQLLQHRPALLASEDNLTLDCLQALLERWGLRVERCLQPRRLNAYLEDF
                     SAPPLLVLAAPWPGPPSIWLDTLYAQLEQGQRILLLCPPQHCQDLPPHEGLRLLALAQP
                     VAVKALREALLELYRERRRQPGRSSEAAPDERPPDAPCILVAEDNPVNQLVVRGFLAKR
                     GYAVRLAGNGRLALDEYLRDPNGIQLILMDGEMPEMDGFEATRLIRREERAQGWPRVPI
                     VALTAHILDEHRRAGIEAGMDAYLGKPVDRAELYATLERLLGQPSRQA"
     PFAM_domain     10004..10402
                     /aSDomain="7TMR-DISMED2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07696.13"
                     /description="7TMR-DISM extracellular 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0400"
                     /evalue="5.70E-33"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="168"
                     /protein_start="35"
                     /score="113.9"
                     /tool="antismash"
                     /translation="AYAEYYRDAGGKARLGDILALPAQAFAALRGDHANFGKNAAAWWF
                     RVRLDNRNGADLAGFLEVNYPLLDDLKVYLLTADGRIEQQESGDLFAFSQRPVQVRNFW
                     FPLRLPPGESTLLLRVQSTSTVYLPLYFS"
     PFAM_domain     10445..11047
                     /aSDomain="7TMR-DISM_7TM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07695.13"
                     /description="7TM diverse intracellular signalling"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0401"
                     /evalue="7.80E-35"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="383"
                     /protein_start="182"
                     /score="120.7"
                     /tool="antismash"
                     /translation="FNGAFYGVLFGLFCYNLFLFVSLREATYAWYLLYNLSLGLFSASF
                     DGLLFKLLPGHVALESAGIYLLMYLSCLVSIQFSRGYLYTRRDFPRLDRFLRGLLLACV
                     VLLASEPLVGLRAWNVLASLTVMLVSLSLLLAGVHVWRQGLRYGLYYILAWGALLLSFL
                     VTTAASLGFELFGLFGSSVVKIGMTVELVTLSIGLADR"
     PFAM_domain     11117..11314
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0402"
                     /evalue="1.80E-19"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="472"
                     /protein_start="406"
                     /score="69.6"
                     /tool="antismash"
                     /translation="AKSRFLAKMSHEIRTPLNGVLGMLQLLRDTPLDRGQAAYVETIAS
                     SGSALMSVINDILDYARIESG"
     PFAM_domain     11453..11800
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0403"
                     /evalue="1.90E-32"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="634"
                     /protein_start="518"
                     /score="112.2"
                     /tool="antismash"
                     /translation="GDPTRLRQVLMNLLSNALKFTAEGHVAVRVQRRFDEGGRERLLYS
                     VSDSGIGISAQAQKTLFESFSQADSSTTRRYGGSGLGLAISRELVQMMGGRIEVSSEPG
                     KGTRFSVDLPLS"
     PFAM_domain     12272..12622
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3543_0404"
                     /evalue="8.60E-22"
                     /label="ctg1_3543"
                     /locus_tag="ctg1_3543"
                     /protein_end="908"
                     /protein_start="791"
                     /score="77.5"
                     /tool="antismash"
                     /translation="ILVAEDNPVNQLVVRGFLAKRGYAVRLAGNGRLALDEYLRDPNGI
                     QLILMDGEMPEMDGFEATRLIRREERAQGWPRVPIVALTAHILDEHRRAGIEAGMDAYL
                     GKPVDRAELYATL"
     PFAM_domain     12710..12910
                     /aSDomain="UPF0270"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06794.14"
                     /description="Uncharacterised protein family (UPF0270)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_3544_0405"
                     /evalue="7.50E-25"
                     /label="ctg1_3544"
                     /locus_tag="ctg1_3544"
                     /protein_end="67"
                     /protein_start="0"
                     /score="86.9"
                     /tool="antismash"
                     /translation="MLIPHDLLEADTLNNLLEDFVTREGTDNGDETPLDVRVERARHAL
                     RRGEAVILFDPESQQCQLMLRS"
     CDS             12710..12940
                     /locus_tag="ctg1_3544"
                     /transl_table=11
                     /translation="MLIPHDLLEADTLNNLLEDFVTREGTDNGDETPLDVRVERARHAL
                     RRGEAVILFDPESQQCQLMLRSEVPAELLRD"
ORIGIN
        1 gcgttccttg aagcgctcca tctgggtctg cttgtcgatc gccagccaga acttcaccac
       61 gatgatcccg tactcgctga gctgctcctc gaagtcattg atctcgccat aggcgcgtag
      121 ccagtcggcc ggtgcgcaga agccctcgat gcgctccacc agcacgcggc cgtaccagga
      181 acggtcgaag atggtgaact ggcgacgcgc cggaatgtgc cgccagaagc gccagagata
      241 gggctgcgca cgctcctctt cggtcggcgc ggcgatcggc acgatatggt actggcgcgg
      301 gtccagcgcg tcggtgacac ggcggatggc gccgcccttg ccggccgcgt cgttgccctc
      361 gaacaccgcg accagcgaat gctggcggaa gcgcttgtcg cggatcagcc cggccaggcg
      421 cgcctgctcg gcggcgagct gctccttgta ggcgtccttg tccaggtact ggcccaggtc
      481 cagggagtcc agcaggccac ggttgtccag gctcgacacc agcggtgcgg cgtgcggctg
      541 gcgcttggcg cgctccttgg tggccagcgc ggcctgcaac ccttcgagaa ggatgcggcc
      601 gacggtcagg gcgcggtagc gctcgtccgc gccttccacc acgtaccagg gcgcgtagtc
      661 ccggctggta cggcgcagca cacgctcgcc gtaatgcacg aagcggtcgt agacctcgct
      721 ctgcttccag tccagcggac tgagcttcca actgtgctgc gggtccttct ccagcgcctt
      781 gagacgctcc ttcaactgtt tcttggagag atggaaccag aacttgaaga gcagcgcgcc
      841 ttcgtcgcag agcatgcgct cgaagcgttc ggcggcatcg atggcctggt ccagcttggc
      901 ctccttgata tgcccctcga cccgcgcgta gagcatctgg ctgtaccagt tgccgaagaa
      961 gataccggtc cgccccttgg gcggcaggcg ccgccagaag cgccactgcg gcggccgctc
     1021 cagctcctcg tcggaaggac ggaggaagct ctgcacctcg attaggcgcg ggtccatcca
     1081 ctcgttgagc agcttgaccg tctcgccctt gccggcgccc tcgatgccgt tgatcaggat
     1141 gatcaccggg aagcgcgcct gctgcttgag ctcgaactgc gcctcgagca gcgcttcgcg
     1201 caactcgatg acggccttct cgtaggtgtc cttgtcgatg ctgtggccaa cttccgcgga
     1261 ttcgaacatg gaggtctccc ttaacctgag tccttcaagg tagcggatcg gcgtgcggct
     1321 gtctgcgcgg cgccgcggca tgttcgcgca gcgcctcgcc gctggccggc aaagccccgt
     1381 aaaatgcgcc atccgctttt tcaggttctg ccatgtccga cttccagcat gcccagctcg
     1441 actgggacga aaacggccag ccgctgtccc gcgccttcgg cgacgtatat ttttcccggc
     1501 attccgggct caacgagacg cgccatgtgt tcctcgccac caaccgcctg gccgagcgct
     1561 tcgccgcgct gggcgacggc gaggtgctgt gcatcggcga gaccggcttc ggcaccggac
     1621 tgaacttcct ctgcgcctgg caactgttcg aacgggtcgc gccggccggc gcgcgcctgg
     1681 agttcgtcag cgtggagaaa ttccccctcg ccgccgccga cctgcgccgc gccctggcgc
     1741 tatggccgga actggcgccc tggagcgagg ccctgctggg ccagtacctt gccgtgcacc
     1801 cgggcttcca gcgcctggcg ttcgcgggcg gaagggtcgg cctgaccctg ctgctgggcg
     1861 atgccctgga gtgcctgccg cagctcgacg cgcgggtcga cgcctggttc ctcgatggct
     1921 tcgccccggc gaagaacccg gacatgtggt cgcccgtact gttcgccgaa ctggcgcgac
     1981 tgtcggcgcc gcaggcgacc ctgggcacct tcaccagcgc cggtttcgtc cgccgcgggc
     2041 tggtcgaggc cggtttcgcc atgcaacggg taccgggcta cggacagaag cgcgagatgc
     2101 tcagcggcac ctaccagggg ccgccggcga acgccggcaa gccctggtac gcacgccccg
     2161 cgccccacgc cgggcgccgc gcggcactgg tggtcggcgg cggcctggcc ggctgcgcca
     2221 gcgccgccag cctcgccgcg cgcggctggc aggtgaccct gatcgaacgc catcccggcc
     2281 tcgcccggga agcctcgggc aacccccagg gcgtgctcta cctgaaactc tcggcccacg
     2341 gcacgccgct gtcgcgcctg gtgctcagcg gcttcggcca tacccgccgg ctgctcgaac
     2401 gcctgcggcg cggccacgac tgggacgcct gcggcgtact gcaactggcc ttcgacgcca
     2461 aggaagcgca acgccaggcg caactggccg cagccttccc cgccgacctg ctgcacggcc
     2521 tggagcgcga gcaggccgag cgcctcgccg gcgtcgccct gcccgccggc ggcctgttct
     2581 atcccgaagc cggctgggtc catccgcccg cgctgtgcca ggccctggcc gccacccccg
     2641 ggatcaccct gctgagcggc cgggcagtac gcttgcgccg cgagggcgac gactggtgcg
     2701 cctacgccgg cgacgaatgc ctggcccgcg cgccactcgc gatcctcgcc accgccgccg
     2761 acatccgcga cttcccgccc gccgccgagc tgccgctgaa gcgcattcgc gggcaggtca
     2821 cccgcctgcc ggccaccccg caaagccggg cgctgcgcac cgtggtctgc gccgagggct
     2881 acgtcgcacc gccgcgtggc gacgaacaca ccctcggcgc cagcttcgac ttcaagagcg
     2941 aagacctggc gccgaccctc gccgaacacc agggcaacct cgaactgctg cgggaaatat
     3001 cccccgatct gttgcagcgc ctgggcgccg acgacctgcc gctggagcgc ctggaaggcc
     3061 gcgcggcatt ccgctgcacc agccccgact acctgcccct ggtaggcccg ctggccgagc
     3121 gcgcggcctt cgacgaggcc tacgcggtgc tcgcccgcga cgcccgccag gtgccggagc
     3181 gtgcctgccc ctggctgcca ggcctgtacc tgaacagcgg ccacggctcg cgcgggctga
     3241 tcagcgcgcc gctgtccggc gaactgctgg cggcgtggat ctgcggcgag ccgctgccgc
     3301 tgccgcgcgc ggtggccgag gcctgccacc cgaaccgctt cctgctgcgc gacctggtgc
     3361 gcgggcagcg cggctgaagc cccgggcgca ccgatttgcg ctacccttcg ggcctgccgc
     3421 acgcgcaggc cataccggac caccggctgg ctcacccgcg gaaatagttg atcgacgatg
     3481 gatgtactgc tcttcgaatc cctgggcatc ggcgccattc tcggcctgct gctcggcctc
     3541 accggcgccg gcggctcgct ggtcgccctg cccctgctgc tcagcctgca cctgccgctg
     3601 cgcgacgcca tcggcgtgag cctcggcgcg gtcgccctgt cggcgctgat tggcgccatt
     3661 ccgcgcgcgc gccagggcca ggtggcctgg cggccggtgc tggtcctggc gctggccggc
     3721 ctgccgagca acgccgtcgg ccaatggctc ggccgcttcg tcccggaagg cgtgctgatc
     3781 gtcgccttct gcctgctggt gctctggtcg gcctggcgca tgtggcgcgg cgccgggatg
     3841 aaacgcgagg ccagcgacca ggcacggagc ctgccgctgc tcggcatcgg cctggcggtc
     3901 ggcttgctgt cgggattgat gggcgtgggc ggcggcttcc tagtggtgcc ggggctactc
     3961 tggttcaccc cgctgtcgat gatggccgcc accgccacct cgatggcggt gatcgcgctg
     4021 gtctccggcg gcggcttcct gatctacctg accggcgccc acccgccgct gccgctgctc
     4081 ggcggcctcg ccgccggcgg cgcggtcggc gtgctcggcg gcaacctgct ggcgcagcgc
     4141 ctcggcggcc cgaccctgca acgcctgttc gcgctgatgc tggtggcggt gagcttctcc
     4201 ctggcggcgc agaagctcta cggcgggtag ctttcctcgg cggccggggc accggggaag
     4261 cggcgttatg cgccctacgc gaaggtcacg ccatggcgta caacgcgctt gtccaccagg
     4321 catcggcagg ttcgccaggt aaagaccgcc gacgcgactg tctttcgtag cgaacctggc
     4381 gccctcactc ttcttcgacg tcctcttccg gcaagccgaa caggtcggcc gcgcgcagca
     4441 gcgcggccag caggccgtgg cgctcccact cgggcaacgc ggcgaagcgc tcgatcacgt
     4501 actccggcaa tagcggcggc gcctccgcca gggcttcgtg gccggccggg tcgaggtgca
     4561 gccaggactt gcgccggtcc tgttcgtcgc gccgacgata gagcaggccg cgtccttcga
     4621 ggcggtcgag cacgccggag agcgatgcct gggacaggct gaccagcttg gccagttgcg
     4681 tcgcggtcag ttctccctcc accgccagga catgcaggat cagcaattgc agcggggtca
     4741 ggccaccgta tcggctgaga cgcttggagt ggatttcggc ggcctgctgg agacggcgga
     4801 tggcgcggaa aatagcgagc gaataggtat cggcagcggt cttattactt tcaaccataa
     4861 taaattcttc gttaagggtc ctgataggcc cggaaaattc gtatagaact ccttccaact
     4921 gtaacggtcc tctgttaggt aagtcatgta cccggaaggg gtacgcaacc cacttcccca
     4981 acggagaacc ggtaaggaat atgtgcggca tatcaggaga gtttcgtttc gacaaccagg
     5041 cagccgacct cgcagcggtc gaacgcatca cccaccacct ggcccctcgc ggccccgacg
     5101 cctggggctt ccacgcccag ggtccgatcg ccctcggaca tcgacggctg aagatcatgg
     5161 acctggcgga agcttccggc caaccgatga tcgatcccga tctcggcctg gccatggtgt
     5221 tcaatggcgc catctacaac taccccgaac tgcgtggcga actggaaagc cttggctatc
     5281 ggttcttctc cggcggcgac accgaagttc tcttgaaggg gtaccatgcc tggggcgccg
     5341 atttattgcc ccggctcaat gggatgttcg ccttcgccgt ctgggagcgc gatcgccagc
     5401 ggctgttcct ggcccgtgac cgactcggca tcaagccgct ctactacagc ctcgaccgct
     5461 cgcgcctacg cttcgcctcg agcctgccgg ccctgctcaa gggcggcgac atcgccagcg
     5521 acctcgatcc gcaggcgctg aatttctacc tcaacttcca cgccgtggtt cccgccccgc
     5581 acaccttgct ggagggcgtg aagaagctgc cgccggcgac ctggatgagc gtcgacctcg
     5641 acggcagctg cgagcagcgc acctggtgga cgctggacta cggcccacgc ccggacgagc
     5701 gcgagctgac gctcgacgac tggcaggagc gcgtcctcga cggcctccgc gaagcggtgg
     5761 cgatccgcca gcgcgccgcc cgcgaggtcg gcgtgctgct ctccggcggg gtcgattcga
     5821 gcctgctggt gggcctgctg cacgaagccg gggtggacaa cctgctgacc ttctccatcg
     5881 gcttcgagga tgccggcggc gagcgcggcg acgagttcca gtattccgac ctgatcgccg
     5941 agcgctatca cacccgccac catcgcctgc gcatcggcga gcacgaagtg atcgagcagt
     6001 tgccggcggc cttccgcgcc atgagcgagc cgatggtcag ccacgactgc atcgccttct
     6061 acttgctcgc gcgggaagtc tcgaagcact gcaaggtggt gcagagcggc cagggcgccg
     6121 acgagctgtt cgccggctac cactggtatc cgaaggtgga tggcgccgac gacgccttcg
     6181 ccgcgtaccg cgcggcgttc ttcgaccgcg accacgagga atacctggcc accgtcggcg
     6241 agcgcttccg cgtcgaggac gtcgccgggc gcttcgtccg cgaccacttc gccagccccg
     6301 gcgccgaggc cgcggtggac aaggcgctgc gcctggatag cacgatcatg ctggtcgacg
     6361 acccggtcaa gcgggtcgac aacatgacca tggcctgggg cctggaagcc cgcgtgccgt
     6421 tcctcgacta ccgcctggcc gagctgtcgg cgcgcattcc cgcccgcttc aagctcggcg
     6481 acggcggcaa gcaggtgctc aagggtgccg cgcgcaaggt gattcccagc gaagtcatcg
     6541 accggcccaa gggctacttc ccggtgcccg gcctcaagca cttgcagggc cgcacccgcg
     6601 aatgggtacg cgaactgctg ctcgacccga gccaggaccg cggcctgttc cagccggcga
     6661 tattcgatcg cctgctgagc gatccggacg gcgacctcac accgctgcgc ggctccaagc
     6721 tgtggcagct ggccgccctc aacctctggc tcagcgaaca gggactttga aaatgggccc
     6781 ccaacgcagg ggcccgaacc aggagcgatc atgaaaggcc acttgcatct gcctcacccg
     6841 cacaaccagc gcctgcaacg tatccaggcg cccacctacg aacgcctcca ggcgcgtctc
     6901 gccgaagatc acagcgagcc caccgagaaa ccgctgagca tccactgcgg ctggggccgc
     6961 ctgctgatcg ggcagaccta cccggacgcc gaggaattgg cccgcgacct gttgcaggaa
     7021 gcccccggcg aacgcgacat cgcgctctac gtggcggcgc cgcagcaggt cctggcccac
     7081 gccccgcagc agctcttcct cgatccctcg gataccctgc gcctgtggtt caccgactac
     7141 cgcccggcgc gccgtccgcc acgcggtttc cgcatccgcc gggtgcatac cgaggaggac
     7201 tgggcggcga tcaaccgcct gtacctggcg cgcggcatgc ttccggtgca gaccgagcgc
     7261 ctcagcccgc gacaccaggg cgggccgatc tactggctgg ccgaggacgc cgacactggc
     7321 gtcgcggtag gcacggtgat gggcctcaac cacgccaagg cgttccagga tccggagggc
     7381 ggctccagcc tctggtgcct ggcggtggac ccgcaatgca gccggccggg cgtcggcgag
     7441 gcgctggtac ggcacctggt cgagcacttc atgagccgcg aactggctta cctcgacctc
     7501 tcggtgctgc acaacaacca gcaggccaag gcgctctacc gcaagctcgg cttccgcgaa
     7561 ctggcgacct tcaccatcaa gcgcaagaac ggcatcaacc agtcgctgtt cctcggcccc
     7621 ggcccggagg aagacctcaa cccctacgcc cggatcatcg tcgacgaagc ccaccggcgc
     7681 ggcatcgagg tgcgcgtcga cgacgccgag ggcggcctgt tcaccctgac ccagggcggc
     7741 cggcagatcc gctgccgtga atcgctctcc gacctgacca cggcggtgag catgaccctc
     7801 tgccaggaca aggtcctcac ccaccgcgcc ctgcagcacg ccggcctgcg ccagccacag
     7861 cagcgcctgg ccggcagcgc ggaggaaaac gccgcgttcc tcgccgagca cggttcgctg
     7921 gtggtcaagc cggtggacgg cgagcagggc cagggcgtgg cggtggacct gcgcaccgcg
     7981 gaagaggtcg aggaggccat cgaggccgcc cgccatttcg attcgcgcgt gctgctggag
     8041 agctaccacg ccggccacga cctgcgcgtg ctggtgattg gctacgaggt ggtggccgcc
     8101 gccatccgtc gtcccgccgc ggtgatcggc gacggccggc acagcatccg cgagctgatc
     8161 gaggcgcaga gccgccggcg ccaggccgcc accggcgggg aaagccgcat cccgctcgac
     8221 cacgagaccg agcgcaccct gcgggccgcc ggctatggct acgacgacgt gttgcccagc
     8281 ggcgaacacc tggccgtgcg gcgcaccgcc aacctgcaca ccggcggcat cctcgaggac
     8341 gtcaccgacg ccctccatcc ggccctccgc gaggccgcga tccaggccgc gcgggccctg
     8401 gaaataccgg tggtgggcct agacttcctg gtcgaggccg ccgaccagcc cgactacgtg
     8461 atcatcgaag ccaacgagcg cgccggcctg gccaaccacg agccgcagcc gaccgccgaa
     8521 cgcttcgtcg atcttctctt ccccctcagc cgcgaggtgc cttcatgacc cctctgccac
     8581 aaccggacct caactacctg caacgggtgc tgctggagat gctcgccatc cccagcccca
     8641 ccggcttcac cgataccatc gtgcgctatg tcgccgagca gctcgacgaa cttggcgtgc
     8701 ccttcgagat gactcgccgg ggaaccatcc gcgcgaccct ccagggccgc ctgaataccc
     8761 cggaccgggc ggtttccgcg cacctcgaca cgatcggcgc gctggtccgc gagatcaagc
     8821 ccaacggccg cctcggcctg gccccggtag gctgctggtc gagccgtttc gccgagggta
     8881 gccgggtcac ggtgttcacc gaacagggcg tgttccgtgg cagcgtgctg ccgctgctgg
     8941 cctcgggcca cgccttcaat accgaggtgg acaacctgaa gatcagctgg gacaacatcg
     9001 agctgcgtct cgacgcctat accgccagcc gcgccgacag cgagagcctg ggcatctcgg
     9061 tgggcgacta cgtggccttc gatccgctgc cggagttcac cgagagcggc catatcagcg
     9121 cccgccacct ggacgacaag gccggggtcg cggcgctgct ggcggcgctg aaggcggtca
     9181 aggaaagcgg ccaggagccg ccgatcgact gccacccgct attcaccatc accgaggaag
     9241 tcggttccgg cgccgccggc gccctaccct gggacgtcag cgagttcgtc ggcatcgaca
     9301 tcgccccggt ggccgaaggc cagaattcca acgagcacag cgtcagcgtg gccatgcagg
     9361 actccggcgg gccctacgac ttccatctgt cgcggcacct gctgcggctc ggcgagcgcc
     9421 acgacatcgc cctgcgccgc gacctgttcc gctactacca cagcgacgcg cagtcggcga
     9481 tcgccgccgg ccacgacacc cgcgccgcgc tgctggcgtt cggctgcgac gccacccacg
     9541 gctacgagcg cacgcacatc gacagcctcg ccgcgctgag ccgcctgctt accgcctaca
     9601 tcctcagccc gccggtcttc gccagcgacg ccaagccccg ggaaacctcg ctggaacgct
     9661 tcaacaagca gctcgagcat ccggtgcaca tggaaagctg cacccacgtc ccgccggtgg
     9721 acgaagtgct cgacagcagc aacaacagcg acaagggctg agcccgcgcc ggcctccccg
     9781 ccccccgggg aggccgccct cctctccagc caactgctag gctgatggca ggttccctcg
     9841 cctgtctcat ttcctccgta gcatcatgcg tgccgactcg tgtccatgga gtagttgcat
     9901 gtcccgactc tgcctggtcc tgctgttgct ctgctgcgcg ctgccggccc gggcgcagcc
     9961 gcccgcgccg ctggacggag aggacctgcg cctgtccctg ggcgcatacg ccgagtacta
    10021 ccgcgacgcc ggcggcaagg cgcgcctggg cgacatcctc gccttgccgg cccaggcctt
    10081 cgccgccctg cgcggcgacc acgcgaactt cggcaagaac gccgcggcct ggtggttcag
    10141 ggtgcgcctg gacaaccgca acggcgccga cctggccggt ttcctggagg tcaactaccc
    10201 gctgctggac gacctcaagg tctacctgct gaccgccgat gggcgcatcg aacagcagga
    10261 gagcggcgac ctgttcgcct tctcccagcg cccggtgcag gtgcgcaact tctggtttcc
    10321 gctgcgactg ccgcccggcg agagcaccct gctgctgcgc gtgcagagca ccagcaccgt
    10381 ctacctgccg ctgtacttca gcacctacgc ggccagcgcg gccagccagg aaaccctgat
    10441 gggcttcaac ggggccttct acggggtgct gttcgggttg ttctgctaca acctgttcct
    10501 cttcgtctcg ctgcgcgagg ccacctacgc ctggtacctg ctgtacaacc tcagcctcgg
    10561 cctgttttcc gccagcttcg acggcctgct gttcaagctg ctgcccggac acgtggcgct
    10621 ggagtcggcc ggcatctacc tgctgatgta cctgagctgc ctggtgtcga tccagttcag
    10681 ccgcggctac ctctacaccc gccgcgactt cccgcgcctc gaccgcttcc tccgcggcct
    10741 gctgctggcc tgcgtggtcc tgttggccag cgagccgctg gtggggctgc gcgcctggaa
    10801 cgtcctcgcc agcctgacgg tgatgctggt ctccctcagc ctgctgctgg ccggcgtcca
    10861 cgtctggcgc cagggcctgc gctacggcct ctactacatc ctggcctggg gcgcgctgct
    10921 gctgtcgttc ctggtcacca ccgccgcctc gctgggcttc gaactgttcg gcctgttcgg
    10981 cagcagcgtg gtcaagatcg gcatgaccgt ggaactggtg accctgtcca tcggcctcgc
    11041 cgaccgcatc aatgcgctca aggaggaagg cttccgctcg cgccaggcgg ccgagcaggc
    11101 gcgggtggag aacgaggcga agagccgctt cctggcgaag atgagccatg agattcgcac
    11161 cccgctgaac ggcgtgctgg gcatgctgca actgctccgc gacaccccgc tggaccgcgg
    11221 ccaggcggcc tacgtggaga ccatcgccag ctccggcagc gcgctgatgt cggtgatcaa
    11281 cgatatcctc gactacgctc gcatcgagtc cggcaagctg cacctggagc gcatcgactt
    11341 cgacctggag gaactgctct ccgacaccct ggcgctgttc agcgcccagg ccgtggaaaa
    11401 acgcctgcac ctgcatctcg gcctggacag gggcgtgccg cgccgcctca acggcgaccc
    11461 gacgcggttg cgccaggtac tgatgaacct gctcagcaac gccctcaagt tcaccgccga
    11521 aggccatgtc gccgtgcgcg tgcagcggcg cttcgacgag ggcggacgcg agcgcctgct
    11581 gtacagcgtc agcgacagcg gcatcgggat atccgcccag gcgcagaaga ccctgttcga
    11641 atccttctcc caggccgact ccagcaccac ccgccgctac ggcggcagcg gccttggcct
    11701 ggcgatcagc cgcgagctgg tgcagatgat gggcgggcgc atcgaggtga gcagcgagcc
    11761 gggcaagggc acccggttca gcgtcgacct gccgctcagc cccgccctcg acgccggcga
    11821 agcggacgaa ctggcgcaac tgctgcaaca ccgcccggcc ctgctggcca gcgaggacaa
    11881 cctgaccctg gactgcctgc aggcattgct ggagcgttgg gggctgcggg tcgaacgctg
    11941 cctgcagccg agacggctga acgcctacct ggaggacttc agcgcaccgc ccctgctggt
    12001 cctggcggcg ccctggccgg gaccgccgtc gatctggctg gacaccctct atgcgcaact
    12061 ggagcaaggc cagcgcatcc tcctgctatg cccgccgcag cactgccagg acctgccgcc
    12121 gcacgaaggc ctgcgcctgc tggccctggc ccagccggtg gcggtgaagg ccctgcgcga
    12181 agccctgctg gaactgtacc gggagcggcg ccgacagcca gggcggagca gcgaggcggc
    12241 cccggacgaa cgccccccgg acgccccatg catcctggtc gccgaggaca acccggtgaa
    12301 ccagctggtg gtgcgcggct tcctcgccaa gcgcggctac gcggtgcgcc tggccggcaa
    12361 cggacggctc gcgctggacg agtacctgcg cgatccgaac ggcatccagt tgatcctgat
    12421 ggatggcgag atgccggaaa tggacggctt cgaggcgacc cgcctgatcc gccgggagga
    12481 gcgtgcccag ggctggccgc gcgtaccgat cgttgccctg accgcgcaca tcctcgacga
    12541 acaccgccgg gccggaatcg aggccggcat ggacgcctac ctcggcaagc cggtggaccg
    12601 ggcggaactc tatgccaccc tcgaacgcct gctcggccag ccttcgcgac aggcatgaca
    12661 gtgcgcgatg cgtcgcgcta gcattcgccg ccataccgga gtaccgccaa tgctgatccc
    12721 ccacgacctg ctcgaagccg acaccctgaa caacctgctg gaagacttcg tcacccgcga
    12781 aggcaccgac aatggcgacg agaccccgct ggacgtgcgt gtagaacgcg cccggcatgc
    12841 cttgcggcgg ggcgaggcgg tgatcctgtt cgacccggag agccagcagt gccagttgat
    12901 gttgcgcagc gaggtgcctg cggagctgtt gcgcgactga gtctcggcat cgccccgcct
    12961 ggcggggcgg gttcgccgcc ctgcacaccc cggaaacgcc ggactgcgcc cccgctccgc
    13021 agggcgaata accgctcgcg gtcatccgcc gctcatccgc gacatcggcg gataacgccc
    13081 atggcgttat tcgccctaca caccccgaaa aagccggact gcgccccagc tccgtagggc
    13141 gaataaccgc tcgcggttat ccgccactca tccgcgacat cggcggataa cgcccatggc
    13201 gttattcgcc ctacacaccc cggaaacgcc ggacagcgtc cccgctccgt agggcgaata
    13261 accgctcgcg gtcatccgcc gctcatccgc gacatcggcg gataacgccc atggcgttat
    13321 tcgccctaca caccccgaaa aagccggact gcgccccagc tccgtagggc gaataaccgc
    13381 tcgcggtcat ccgccgctca tccgcgacat cggcggataa cgcccgtggc gttattcgcc
    13441 ctacacaccc cgaaaaagcc ggactgcgcc ccagctccgt agggcgaata accgctcgcg
    13501 gtcatccgcc gctcatccgc gacatcggcg gataacgccc gtggcgttat tcgtcctaca
    13561 cgccccggaa acgccggact gcgcccccgc tccgtagggc gaataaccgc tcgcggtcat
    13621 ccgccgctca tccgcgacat cggcggataa cgcccatggc gttatccgcc ctgcacaccc
    13681 cggaaacgcc ggacagcgcc cccgctccgt agggcgaata accgctcgcg gttatccgcc
    13741 gcttatccgc cgccccctca ctccttcgcc ccaccctcct ccgtctccaa cgccgccctg
    13801 gcgatgttcc ggctatgcgc gccgaaatgc ccgatcagtt cgatcagttg cgcgttcagc
    13861 accgcattgt cgtgggcctc ggggcgtggc tggttgctct cgctgaagtc ctgcgcggcg
    13921 gaggccgggc gggcggccag ccattcgccg atggcggcgt cgaaggccgc ggcgtgggcg
    13981 ttcgactcgg cggccaccac gtcgcgcaag taggtcggcg aataggccgg ataggcaccg
    14041 tcgcggcggg tgtcggcgta ggcgtcgagc atcggctgcg ggcggccgtc gcggagcagt
    14101 tggcgcagcc agtcgaactg gtatttctcc accgcggtat ggcggttcgc gacacgctcg
    14161 atggccgcct gcttttcctc cgggtagccg agcaatgcct tgccctccat ctgtagcatc
    14221 gccgccaggc tggcaccggg cagcggcgtg gagtggtagg gctgggtgat gtcctggatg
    14281 tagtgcatgc cccagccaag gaaccggtag ccccagtagg gatgaccgtt ggcgaaggcg
    14341 aagcgggaca ggccgaagta ctggtaggca cgccattccg gccaggcccg ggcgaggaac
    14401 ggcgcgccgc tgtagatcac cgccgcctcg tgatagaagc ccatgtggaa cggcgcctgg
    14461 gagctgaact cgaagcgcgg gtcgccgaat ggctgggtgc cgaagccgta gcgctggccg
    14521 gcttcgccgg ggttgtcgct gaacaggttg atgtcgtggc cgtagtccgg ttcgtcggcg
    14581 gcggtggcca gcactgccag gggcgcgact cgctcgccgg gctccaggcg gatgaaacgc
    14641 caggcggtcc acggcgagag gttctggaac accagcacct cctgtggctt gaggtgcggg
    14701 cgctgcggct ggtcctgccc gggaagcggc tggagcgcca gcgccaggcg gatctccggg
    14761 t
//
