LOCUS       c00011_NZ_FOLI..       10440 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FOLI01000003.1 Fructobacillus durionis strain DSM 19113, whole
            genome shotgun sequence.
ACCESSION   NZ_FOLI01000003
VERSION     NZ_FOLI01000003
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:27
            Original ID  :: NZ_FOLI01000003.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 17669
            Orig. end    :: 28109
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10440
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[22669:23109]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5440
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10440
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10440
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             1243..1680
                     /locus_tag="ctg11_17"
                     /transl_table=11
                     /translation="LAKFNPKQMQYYVTTLQEVLQNTQDTADHVSPFFVKLDEAKQADK
                     VADMAKAEFGEIKAEFDDAVAAYEKNAKTLAALQVPVRFMGVHKTLAKAYADYAAATKM
                     MADALDEKNQSINEADFAQSEKDQETFLGKIQAQVAKIFGA"
     CDS             1836..2198
                     /locus_tag="ctg11_18"
                     /transl_table=11
                     /translation="MKLKDLAVANGIVGLAGGIVLLFGVFMVAGAATSDILIGGDSISP
                     MVIILGCLKVAILTLGIIGLTEFNKNPIITKSPSVLLIVGGAIALVPLLGWVGGIISIV
                     GGSMYLANLKKFDDAK"
     CDS             complement(2258..2494)
                     /locus_tag="ctg11_19"
                     /transl_table=11
                     /translation="MINFTVSNEPMKNNDTVEFYVHSGYSASKRSWFVCVENAIPFYKK
                     WYCSSEKAADEQAKELSQQIRSGRFQKKMTYQF"
     CDS             complement(2727..4436)
                     /locus_tag="ctg11_20"
                     /transl_table=11
                     /translation="MKNTLTTASQKEHKVLHKIKKNWVVLSFSTLALLGAGSLVSNEGT
                     HLLPSGTISASADTNVTTGTLGTVSYTYDNSTNTLTFTSGGTLPPASNDEQRIDRLFQH
                     LQHIVFTQTVQAPKDSTRLFAMLHSLQDFTGLNYLDTSNVTSMNAMFNQESTITSLDLS
                     GFDTSKVTDMSWMFTKTNNLQTVNLSSFNTSNVTTFEATFMESGLQSLNLSSFDTSKVV
                     FMNDTFSHMANIQSLDLSNFNTASLTDMHSLFEGSTALKSVDISSFNTDKIVTKITVGT
                     EHKVLDKTGVSDMFENTGNGSTLAIKLPSASFYNDAGLGNGYSAFVAVNGGTVTDPKGT
                     LLTKAAFQNIFSTGAKTSDWYVCSSLTKTTQNKTLTRTVNYVDANGNEITGQAPTTQTL
                     HFHRTVTGLAGTNYKSYSDWEADSTADQAFDNIDVPQSLNDGQLINPTVNGKNVKTIST
                     NLPTLDDNDAQTENVNVIYSAKSADTPSNNNDNGGPSSNNSGSDSSNNGTNNSNNNRSS
                     HHSLTLPSTGGNESLAAALPATAKVVSKNVFITVPFLFTSLAAGLYFTTKKR"
     PFAM_domain     complement(3129..3320)
                     /aSDomain="Muc_B2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17966.3"
                     /description="Muc B2-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_20_0002"
                     /evalue="1.10E-07"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="436"
                     /protein_start="372"
                     /score="32.6"
                     /tool="antismash"
                     /translation="KTLTRTVNYVDANGNEITGQAPTTQTLHFHRTVTGLAGTNYKSYS
                     DWEADSTADQAFDNIDVPQ"
     aSDomain        complement(3621..3680)
                     /aSDomain="TIGR02167"
                     /aSTool="tigrfam"
                     /description="Liste_lipo_26: bacterial surface protein
                     26-residue repeat"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_20_0005"
                     /evalue="5.20E-05"
                     /identifier="TIGR02167"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="272"
                     /protein_start="252"
                     /score="20.9"
                     /tool="antismash"
                     /translation="LFEGSTALKSVDISSFNTDK"
     aSDomain        complement(3684..3758)
                     /aSDomain="TIGR02167"
                     /aSTool="tigrfam"
                     /description="Liste_lipo_26: bacterial surface protein
                     26-residue repeat"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_20_0004"
                     /evalue="2.50E-07"
                     /identifier="TIGR02167"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="251"
                     /protein_start="226"
                     /score="28.3"
                     /tool="antismash"
                     /translation="TFSHMANIQSLDLSNFNTASLTDMH"
     aSDomain        complement(3774..3821)
                     /aSDomain="TIGR02167"
                     /aSTool="tigrfam"
                     /description="Liste_lipo_26: bacterial surface protein
                     26-residue repeat"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_20_0003"
                     /evalue="6.00E-05"
                     /identifier="TIGR02167"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="221"
                     /protein_start="205"
                     /score="20.7"
                     /tool="antismash"
                     /translation="SGLQSLNLSSFDTSKV"
     PFAM_domain     complement(3822..4061)
                     /aSDomain="DUF285"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03382.16"
                     /description="Mycoplasma protein of unknown function,
                     DUF285"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_20_0001"
                     /evalue="1.90E-13"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="205"
                     /protein_start="125"
                     /score="50.3"
                     /tool="antismash"
                     /translation="MLHSLQDFTGLNYLDTSNVTSMNAMFNQESTITSLDLSGFDTSKV
                     TDMSWMFTKTNNLQTVNLSSFNTSNVTTFEATFME"
     aSDomain        complement(3840..3911)
                     /aSDomain="TIGR02167"
                     /aSTool="tigrfam"
                     /description="Liste_lipo_26: bacterial surface protein
                     26-residue repeat"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_20_0002"
                     /evalue="3.90E-04"
                     /identifier="TIGR02167"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="199"
                     /protein_start="175"
                     /score="18.1"
                     /tool="antismash"
                     /translation="MFTKTNNLQTVNLSSFNTSNVTTF"
     aSDomain        complement(3912..3989)
                     /aSDomain="TIGR02167"
                     /aSTool="tigrfam"
                     /description="Liste_lipo_26: bacterial surface protein
                     26-residue repeat"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_20_0001"
                     /evalue="2.70E-08"
                     /identifier="TIGR02167"
                     /label="ctg11_20"
                     /locus_tag="ctg11_20"
                     /protein_end="175"
                     /protein_start="149"
                     /score="31.4"
                     /tool="antismash"
                     /translation="MFNQESTITSLDLSGFDTSKVTDMSW"
     CDS             complement(5001..5192)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_21"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 3.7e-11,
                     bitscore: 36.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLEIKVLNNNQLSKITGGKKINWGSVGGSCIKGALFGAAFGGNA
                     IGGCAGSAAADASLQFFF"
     aSDomain        complement(5136..5180)
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_21_0006"
                     /evalue="2.30E-03"
                     /identifier="TIGR01847"
                     /label="ctg11_21"
                     /locus_tag="ctg11_21"
                     /protein_end="19"
                     /protein_start="4"
                     /score="16.5"
                     /tool="antismash"
                     /translation="IKVLNNNQLSKITGG"
     CDS             complement(5201..5440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_22"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4e-14, bitscore:
                     45.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYQLTNTLTSQELAEISGGYSRGQCYKAMASGAAWGALRGGMSGT
                     FAGGPVGTIGGAIAGAHLGAIGGTAACVGGYLFG"
     PFAM_domain     complement(5243..5425)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_22_0003"
                     /evalue="6.60E-09"
                     /label="ctg11_22"
                     /locus_tag="ctg11_22"
                     /protein_end="66"
                     /protein_start="5"
                     /score="35.8"
                     /tool="antismash"
                     /translation="NTLTSQELAEISGGYSRGQCYKAMASGAAWGALRGGMSGTFAGGP
                     VGTIGGAIAGAHLGAI"
     CDS             complement(5611..6114)
                     /locus_tag="ctg11_23"
                     /transl_table=11
                     /translation="MNKKLSSKKLIVTAMLAALAYVLNTMVVFPAMAPFQHFVNVLATY
                     LLGPWYSMTAALLCGSLRMLSGRTIMAVTGGIVGPLLSGYIYKKTENIYLLALGEAIGS
                     GVFGALLSYPFMVAFYGMKAGNWGHLIPFFLPSAALGSLLGLALLLILKKSKLLDRLKK
                     QINK"
     aSDomain        complement(5641..6093)
                     /aSDomain="TIGR02359"
                     /aSTool="tigrfam"
                     /description="thiW: energy coupling factor transporter S
                     component ThiW"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_23_0007"
                     /evalue="1.50E-33"
                     /identifier="TIGR02359"
                     /label="ctg11_23"
                     /locus_tag="ctg11_23"
                     /protein_end="158"
                     /protein_start="7"
                     /score="114.1"
                     /tool="antismash"
                     /translation="KKLIVTAMLAALAYVLNTMVVFPAMAPFQHFVNVLATYLLGPWYS
                     MTAALLCGSLRMLSGRTIMAVTGGIVGPLLSGYIYKKTENIYLLALGEAIGSGVFGALL
                     SYPFMVAFYGMKAGNWGHLIPFFLPSAALGSLLGLALLLILKKSKLL"
     PFAM_domain     complement(5653..6087)
                     /aSDomain="ThiW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09512.12"
                     /description="Thiamine-precursor transporter protein
                     (ThiW)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_23_0004"
                     /evalue="4.80E-33"
                     /label="ctg11_23"
                     /locus_tag="ctg11_23"
                     /protein_end="154"
                     /protein_start="9"
                     /score="114.5"
                     /tool="antismash"
                     /translation="LIVTAMLAALAYVLNTMVVFPAMAPFQHFVNVLATYLLGPWYSMT
                     AALLCGSLRMLSGRTIMAVTGGIVGPLLSGYIYKKTENIYLLALGEAIGSGVFGALLSY
                     PFMVAFYGMKAGNWGHLIPFFLPSAALGSLLGLALLLILKK"
     PFAM_domain     6453..6719
                     /aSDomain="DUF2316"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10078.11"
                     /description="Uncharacterized protein conserved in bacteria
                     (DUF2316)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_24_0005"
                     /evalue="7.30E-31"
                     /label="ctg11_24"
                     /locus_tag="ctg11_24"
                     /protein_end="89"
                     /protein_start="0"
                     /score="106.4"
                     /tool="antismash"
                     /translation="MSLNPTERVNTIRELNENFQLLDWPVEKVAEALQTSPKHLEDVLQ
                     LKTAFIEEPWILKNFLEKQLLVEGKKPVAFSKLTGDPSQYWFLN"
     CDS             6453..6755
                     /locus_tag="ctg11_24"
                     /transl_table=11
                     /translation="MSLNPTERVNTIRELNENFQLLDWPVEKVAEALQTSPKHLEDVLQ
                     LKTAFIEEPWILKNFLEKQLLVEGKKPVAFSKLTGDPSQYWFLNQSRIEAGRLAK"
     CDS             6872..7237
                     /locus_tag="ctg11_25"
                     /transl_table=11
                     /translation="MEKKPKKNNKSSIVLAYSSFILLLFTQNLAFLLGTVIFLVCMRLP
                     ERIVNITEFYKEFMFEVFHVSKYQDYENTEVNFNWMNYLLVVFLVLLFFFSKSWYFLLM
                     ILVPFFDQIFWLYKKRK"
     CDS             complement(7289..8281)
                     /locus_tag="ctg11_26"
                     /transl_table=11
                     /translation="MYYITQTIEPWMPAGALKAKDDLARIAVKNDWQRLAIERYNDVRF
                     SDEIRSSKIDTMLEKVKPGDIILHQFPTYMSEDFEKEFQEAVQKRGATYTLLIHDFEPL
                     RVERQKAWEWQLAEGADLIVAHSQQMIEQFKAHGIHSPAVTINLFDYLGPSPTTNPIFD
                     KVINYAGTWQKAPWLQTYDGPALRLFGSRPKKWKEIELPPAVDWAGSFLPDEIALAFHS
                     GFGLLWDSDYDDKYFQSYTKINAPHKASLYLKAGLPLIVWSQSYLANLVKEFNIGFTID
                     SLDQLENKLGQVDQSGYQRIQKNLQPFQERVSKGHYTKNMLEKVVNFFK"
     CDS             8423..9871
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091:glutamine-binding lipoprotein glnH (Score: 179.6;
                     E-value: 9.8e-55)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg11_27"
                     /transl_table=11
                     /translation="MKKGLLTVLVALSALFAVFGLSKETASASEPNYTITSDATYAPFD
                     FQDKNNQYIGIDQDLLKAIAKAAGFTVTVKPMAFNAAMQSVASSQADGVIAGTTITNER
                     KAVYDFSDPYYKTGIAWATAKNSKIKSLSDLKGKTVALKTGTAGAEYAESIKDQYGFKI
                     TYFSDSDTVYRDVINGNSVATFADMPVLQYTIKNGTALKVQNSKDPFAAGDLGFAVKKG
                     QNAELLADFNKGLAIIKKNGTYDKIINKYLDAKAETFTGSAKDNSTVWGILKTNRSAFW
                     SGLKQTMYLTVVGIILASLWGLLLGVMGVSKNAFVRGLSTTVIYIFRGMPMLVLAFFLY
                     IGIPALLGTKISAWSAGILTLVLNEGAYTGAFVRGGFQSVDSGQMEAARSLGLSHGQAM
                     RKVIIPQGLRLMVPSFINQFIITLKDTSLLSAIGILELTQTGTLIVTRNSQGFRVWAIV
                     AMIYLVVITLLTWFSNWVEKRMNA"
     PFAM_domain     8522..9181
                     /aSDomain="SBP_bac_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00497.22"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_27_0006"
                     /evalue="2.10E-53"
                     /label="ctg11_27"
                     /locus_tag="ctg11_27"
                     /protein_end="253"
                     /protein_start="33"
                     /score="181.2"
                     /tool="antismash"
                     /translation="TITSDATYAPFDFQDKNNQYIGIDQDLLKAIAKAAGFTVTVKPMA
                     FNAAMQSVASSQADGVIAGTTITNERKAVYDFSDPYYKTGIAWATAKNSKIKSLSDLKG
                     KTVALKTGTAGAEYAESIKDQYGFKITYFSDSDTVYRDVINGNSVATFADMPVLQYTIK
                     NGTALKVQNSKDPFAAGDLGFAVKKGQNAELLADFNKGLAIIKKNGTYDKIINKYLD"
     aSDomain        9254..9547
                     /aSDomain="TIGR01726"
                     /aSTool="tigrfam"
                     /description="HEQRo_perm_3TM: amino ABC transporter,
                     permease protein, 3-TM region, His/Glu/Gln/Arg/opine
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg11_27_0008"
                     /evalue="7.70E-25"
                     /identifier="TIGR01726"
                     /label="ctg11_27"
                     /locus_tag="ctg11_27"
                     /protein_end="375"
                     /protein_start="277"
                     /score="85.3"
                     /tool="antismash"
                     /translation="SAFWSGLKQTMYLTVVGIILASLWGLLLGVMGVSKNAFVRGLSTT
                     VIYIFRGMPMLVLAFFLYIGIPALLGTKISAWSAGILTLVLNEGAYTGAFVRG"
     PFAM_domain     9320..9865
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg11_27_0007"
                     /evalue="1.20E-23"
                     /label="ctg11_27"
                     /locus_tag="ctg11_27"
                     /protein_end="481"
                     /protein_start="299"
                     /score="83.9"
                     /tool="antismash"
                     /translation="LWGLLLGVMGVSKNAFVRGLSTTVIYIFRGMPMLVLAFFLYIGIP
                     ALLGTKISAWSAGILTLVLNEGAYTGAFVRGGFQSVDSGQMEAARSLGLSHGQAMRKVI
                     IPQGLRLMVPSFINQFIITLKDTSLLSAIGILELTQTGTLIVTRNSQGFRVWAIVAMIY
                     LVVITLLTWFSNWVEKRMN"
ORIGIN
        1 agttggctga ccaggccctc cgtgtcttag cctttgctga gaagtctttg gcaacactgc
       61 cagccgaagc caagtccgat gaaatggaaa ctggtttgac cttgattggt ttcgtggcca
      121 tgattgatcc tgagcgtcca gaggtaaaag actcggttgc tcaggccaag gctgccggta
      181 tccgcccaat gatgattacc ggtgaccatc ctcagacagc ggcagcgatt gccggccgtc
      241 ttggtatctt ggaagaaacc gatgaccgaa gccaagccgt gatgacgggg gctcaactgg
      301 atgaattgtc ggatgagact tttgaaaagc gggttgaaga cgtcaaagtc tatgctcgtg
      361 tcgcacctgc ccacaaggtt cgaattgtgc aggcctggca gaagaagggc aaggtcgttg
      421 cgatgaccgg agacggcgtg aacgatgcgc ccgccttgaa ggttgctgat atcggggtcg
      481 ccatgggtat caccggaacg gaagtttcca aggaagcggc cgacatggtc ttggccgacg
      541 ataacttctc aaccatcgtt tcagcggtta aggagggacg aaaagtcttt gccaacattc
      601 aaaaggcctt gcagtacttg ctggcttcca acttggccga agtcattgcc atcttcacca
      661 tgactttgct tggttgggag gtcttggcac cggtgatgat tctttggatc aacctagtga
      721 cggatacttt cccagccatt gcactggggc ttgaaccagc acagccaaac atcatgagtc
      781 agaagccccg tggtaaaacg gcgaacttcc tatccggtgg ggttgggcct gccattatct
      841 ggcagggaat tgtgcaggcg gccattgtgc tttctgtcta tggcttggca ttggccttcc
      901 cagaccatgc tggctcaaca ttagtccacg gggatgcctt gacgatggcc ttcatgaccc
      961 ttggtttgat gcagatggta aacgccatta acgtgaagtc cgtttacaac tcggagttga
     1021 acgtgtcagc ctttaagaac cacttcttca atggtgcgct cttcttctct ttcattgcca
     1081 tgatggcagt tgtcgtgatt aagccattga accccatttt ccacgtgaca aacttggatc
     1141 tataccagtg gctaattgtc attggcgcat ccctttctat cattgttatc gttgaactgg
     1201 taaaatgggt acaacgaaca ttttttaatc gaggataaga cattggcaaa atttaaccct
     1261 aaacaaatgc agtactacgt aacgactttg caagaagttt tgcaaaacac tcaagatact
     1321 gctgatcacg tatcaccatt cttcgttaag ttggatgaag caaagcaagc tgataaagtc
     1381 gccgacatgg ccaaggccga attcggcgaa atcaaggctg aatttgacga tgccgttgcg
     1441 gcatacgaga agaatgctaa gactttggct gccttgcaag tgcccgttcg cttcatgggc
     1501 gtacacaaga cattggcaaa ggcctatgcc gactacgctg ctgctactaa gatgatggca
     1561 gacgctttgg atgaaaagaa ccaaagcatc aatgaagcag acttcgctca atctgaaaag
     1621 gaccaagaaa ctttcttggg caagattcaa gcacaagttg ctaagatttt tggagcataa
     1681 ttcaaaagaa acacctctca acgaaacgtt gggaggtttt ttatatgatt tatttcggtc
     1741 tactttagcg ctggtggtat actgaaaaag ttatttccat cgcgttttaa agagatggaa
     1801 tatttttaat atgataatga atagggagag ctttaatgaa gttgaaggac ttagctgtgg
     1861 ctaatggtat tgtgggcctt gccggtggaa ttgtactatt gtttggtgtt tttatggtgg
     1921 ctggtgctgc tacttcagat attcttatcg gcggggatag catttcacca atggttatca
     1981 ttttaggttg cctaaaggtt gcgattctca ctttgggtat catcggcctt acggaattta
     2041 ataaaaatcc gattattacg aaatcaccaa gtgttttgtt aatcgttggt ggagcgatag
     2101 cacttgtgcc cttgttaggc tgggttggag gaattatttc aattgttggt gggtcgatgt
     2161 atcttgctaa tttgaaaaaa tttgacgatg ccaaataaaa acagtcattt taaactaaaa
     2221 aaagaggcta acagtatttg actgttagcc tcctttttta gaattgataa gtcattttct
     2281 tctgaaaacg accagatcga atctgctgtg agagctcttt tgcctgctca tcagctgctt
     2341 tttccgatga acaataccac ttcttataaa aggggattgc attctcaacg caaacaaacc
     2401 atgaacgttt actggcagag tatcctgagt gaacgtagaa ctcaacagta tcattatttt
     2461 tcattggctc atttgaaaca gtaaagttta tcatgatgca cctccgaaag cattgcgtat
     2521 tgatttaata gtagtttagc aatcttatat ttcggctata tgactgataa attacggctt
     2581 aggggcaaat tataaaaatg ttactaattt tgaaatttat tattcggtaa aaggtggagt
     2641 tctcgtttta tttatagccg ttctaaagta aaaagacctc cgagtggaat cggaagtctt
     2701 ttttgtaata atttattaat gaacgattag cgtttctttg ttgtgaaata aagtccggcc
     2761 gcgagtgaag tgaacaagaa tggcactgtg ataaagacat ttttggaaac gactttggca
     2821 gtggcaggta aagcagctgc aagggattcg ttacctcccg ttgaggggag ggtcaatgag
     2881 tggtgagagg aacggttgtt gtttgaatta ttcgttccat tgttacttga atcgcttcca
     2941 ctattgtttg aacttggtcc gccgttatca ttgttgttcg atggtgtatc cgcagactta
     3001 gcgctgtaaa taacatttac attttcagtc tgtgcatcat tatcatccag agtaggaagg
     3061 tttgtggaaa ttgtcttaac attctttccg ttaaccgttg gattgattag ctgaccatca
     3121 ttcaatgatt gcggtacatc aatgttgtca aacgcttggt cagcagttga atcagcttcc
     3181 caatctgagt atgacttgta gttcgttcct gcaagacccg ttaccgtacg gtggaagtgc
     3241 agtgtttgcg ttgttggtgc ttgtccagta atttcattac cgttagcatc aacgtagtta
     3301 accgtacgag tgagcgtttt gttttgggtt gtctttgtta atgaagagca aacgtaccaa
     3361 tcagaagtct ttgcacctgt gctgaaaata ttttggaagg ctgccttcgt aaggagggtt
     3421 cccttaggat ctgtcactgt tccaccatta acagcaacga atgcagaata accgttaccg
     3481 agcccggcat cgttgtagaa agaagcgcta ggcaatttga tggcaagtgt tgatccatta
     3541 ccagtattct caaacatatc gctgacaccg gttttatcga gaactttgtg ttctgtccca
     3601 acggtaattt tagttacaat tttatcagtg ttaaagctgc tgatatcaac tgacttcaag
     3661 gcagttgaac cttcgaagag gctatgcatg tctgtcaggc tggccgtgtt gaagttggac
     3721 aggtccagtg attggatgtt ggccatgtga ctgaatgtat cgttcatgaa cacgactttg
     3781 cttgtgtcga agcttgaaag gtttaaggat tgcaagcctg attccatgaa ggttgcctcg
     3841 aaagttgtta cattgctggt gttgaaactt gaaaggttta ccgtctgtaa attattggtt
     3901 ttagtgaaca tccaggacat atccgtgact ttggaggtat caaatccgga aagatcgagc
     3961 gatgtaatag tgctttcctg attaaacatg gcgttcatcg atgttacgtt actggtatct
     4021 aggtagttca accccgtgaa gtcctgcagg gagtgtaaca tggcaaagag acgtgttgaa
     4081 tccttaggtg cttgaacggt ttgcgtgaaa acaatgtgct gaagatgttg aaaaagtcga
     4141 tcaattcgtt gttcatcatt agaagcagga ggtaatgttc ccccactcgt gaaagtcagt
     4201 gtattggttg aattatcata cgtatatgaa acggtaccta gcgtaccggt ggtaacgtta
     4261 gtatcagcac tggctgaaat tgtgccgcta ggcaataggt gagtaccttc gttggaaaca
     4321 agtgatcccg ctcccagtaa tgctaacgtt gaaaaagaaa gaacaaccca gttcttcttt
     4381 attttgtgta gaaccttgtg ttctttttgg ctagcagttg tcaatgtgtt cttcattgta
     4441 gttcgtattt tctccaagaa aagtgctact ttcatttaaa ttatacttta gaaaatagac
     4501 acaaattatt ttatataaga taaattataa catttatatc atctatattt tatgattgtt
     4561 acatggtagg gcctattcat tctagttaag taagaataaa ataagattaa aagtaagaca
     4621 gaaatacagt gggttgctat cagttttttt caatagaaat tgccaaatag tggttttaga
     4681 aggggtgtca ggttcttgca cgctactggt gggttgtttt tcccagttgg tggctttgcc
     4741 tttggtattt tctcaggcat atagggtgtg atgcatccat aaaaaggaga ctttatcgtc
     4801 tcctttttaa tttctataaa taccagaaaa agttggtgaa gtatgccttt aaaaatgatt
     4861 tggatttatt tccagtaatc ttatttggta cttgtcgata ataatcatca tgtttgggaa
     4921 gggttaaaac gagaacgagt aatgaatacc caaagaagat gattaatatg attagccagt
     4981 tgctcatgag agatgcttat ttaaaagaaa aactgaaggc tcgcgtcagc agcggcagat
     5041 ccagcgcagc ccccaatcgc attgcctcca aacgctgctc caaaaagagc tcctttgata
     5101 catgatccac ccacacttcc ccaattaatt ttctttccac cagtaatttt agaaagttga
     5161 ttattattta aaactttaat ttctaaattc atagattctc ctatccgaat aaatatccgc
     5221 caacacaggc tgctgtacca ccgattgcac caaggtgggc tccagcaatt gctccaccaa
     5281 ttgttcccac ggggcctccg gcaaaagtac ctgacattcc gcctcgcaat gcgccccatg
     5341 cagcaccaga tgccattgcc ttgtaacatt ggcctcggct atatccacca ctgatttctg
     5401 ctagttcttg cgaggttaaa gtattggtta attgatacat attatttctc ctttctttgt
     5461 gacttttatg ttcgtcataa ctgtatcaaa gattgtttgg ataattattg acaaaatgtc
     5521 ataatttttt tcatttttag tgatatatgt taaatgatat tcttcttgtt ctacacaaaa
     5581 aaacgtctcg gttacccggg acgtttttta ttacttatta atttgtttct ttagtctgtc
     5641 aagcagtttc gactttttaa ggattagcaa caaggctagt cctaataaac ttcctagtgc
     5701 tgctgatggc aggaagaagg gaatgagatg accccagtta ccagccttca tgccgtaaaa
     5761 ggcaaccata aatggataag aaagtagggc gccaaagact ccggaaccga tggcttcacc
     5821 cagcgccagt aggtagatat tttctgtttt cttatagata tagccggaaa gcagtgggcc
     5881 gacaatgccg ccagtaacgg ccatgatggt ccggccggag agcatacgta aggaaccgca
     5941 gagtaaagca gcggtcatgc tataccaggg tcctagtagg taagtggcca aaacgttaac
     6001 aaagtgttga aaaggtgcca tggcggggaa gacgaccatg gtattgagta cgtaggcgag
     6061 agcggcgagc atggcagtga caattagctt cttgctggaa agtttcttgt tcattggaga
     6121 actcctttag atattttgta taaaaacaac agtgtatttt tgtacaaatc atgccgaaaa
     6181 agcctccttt cttcgttttg tccacaaaaa aaggacgcct gaaaaagacg tccgcattaa
     6241 aagcgtggaa ataattccta cgacggcatg atccgtatca ggtcaatggg tcggtaatgg
     6301 tattaccctc tcagcccgtc acacggactc cccgaagaaa tattatagat agaagagaag
     6361 aaattgtaca gaaaaagttg aattaattga aaagaagttt aaagtaggtg caaaagaatg
     6421 acgtactttt gtttttcatt gggaggttca aaatgtcgtt aaatccaaca gaacgagtga
     6481 atacaattcg tgagttaaat gaaaactttc aactcttaga ttggccagtc gaaaaggtgg
     6541 ctgaagcatt acagacaagc ccaaagcatt tagaagatgt gcttcagtta aagactgcct
     6601 ttattgaaga accatggatt ttaaaaaact tcttggaaaa gcagcttttg gtagaaggaa
     6661 aaaagccggt tgcttttagt aaattgacgg gagaccctag tcagtattgg tttttaaatc
     6721 aaagtcgcat tgaagccggc cgattagcaa agtaaataaa aagaagtcac ggagttgttg
     6781 gttttaatat gaaagaccga aatatttaca gataaatcaa gctatgatag catcttatta
     6841 ttatattttt tgactatttg aaaggaatac tatggaaaag aagccaaaaa agaataataa
     6901 gagttcgatt gttttagcct atagttcatt tatcctattg ttgtttactc aaaatcttgc
     6961 cttcctgctg gggactgtta ttttcctggt ttgtatgcgt ctgccagaac ggattgttaa
     7021 tataacagaa ttctataaag agttcatgtt tgaagtattt catgtaagta aatatcagga
     7081 ttatgaaaat actgaagtta atttcaattg gatgaactac cttttggttg tattcttagt
     7141 tttgttattc ttttttagta aatcttggta tttcctttta atgatattgg ttcctttttt
     7201 tgatcaaata ttttggcttt ataaaaaaag aaagtaatgt cgatttttct tatacaaaaa
     7261 aagcagtttc ccctgggaaa ctgctttttt atttgaagaa atttaccact ttttctagca
     7321 tgttttttgt gtagtgacct ttgctgactc tttcttggaa tggctgcaga tttttttgta
     7381 ttctttggta tccgctttgg tcaacttgtc caagtttatt ttctaattga tctagtgaat
     7441 caatggtgaa cccgatgttg aactctttaa ccagattggc taagtatgat tgcgaccaaa
     7501 cgatgagagg taagccagct tttaaataga gggaagcttt atgtggtgcg ttgatcttcg
     7561 tataactttg aaaatactta tcgtcatagt cggagtccca gagaagtcca aaaccggagt
     7621 ggaaagcgag agcgatttcg tccggtaaaa aagagccggc ccaatcaacg gctggtggga
     7681 gttcgatttc tttccacttc ttagggcgag atccaaagag tcggagcgca gggccgtcgt
     7741 aagtttgtag ccaaggggcc ttctgccagg taccggcgta gttaatgact ttgtcaaata
     7801 ttgggttagt agttggggat gggcccaggt aatcaaaaag gttgatggta acggccgggc
     7861 tgtgaatacc gtgtgcttta aattgttcaa tcatttgctg actgtgggca acaattaggt
     7921 cggccccttc tgctagttgc cattcccagg ctttttggcg ttcgacgcgg aggggttcaa
     7981 agtcgtgaat caataaggtg tatgtagcac cgcgcttttg aacagcctct tggaactcct
     8041 tttcaaagtc ctctgacatg taggttggaa attggtgaag aataatatcg ccgggtttta
     8101 ccttttctag catcgtgtca attttgctac tgcggatttc gtcagaaaaa cgaacgtcgt
     8161 tgtatcgttc gatggctagt cgctgccagt cgtttttgac tgcaatacgt gctaggtcgt
     8221 cttttgcctt tagagcgcca gcgggcatcc agggttcaat tgtctgtgta atgtaataca
     8281 tggttttttt ctaatttttc tccaataaaa ctggaataag gactagaccg attgataaaa
     8341 cgatgttaga atatctaacg taattcagaa tcccttgtaa ttggcctgct agactgaagt
     8401 taacaatgca agaggggtta ccatgaaaaa aggattatta acggttttgg tggcgctttc
     8461 tgcgcttttt gctgtttttg gactttccaa ggaaacagca agtgccagtg agccaaatta
     8521 taccattacg tcggatgcaa cttatgctcc gtttgacttt caggacaaga ataatcaata
     8581 catcggtatt gatcaggatt tgttaaaggc tatcgcgaag gcagcgggct ttacagttac
     8641 tgttaagcca atggccttta acgcagccat gcagtcagtt gcttcatcgc aagccgatgg
     8701 ggtgattgct ggtacgacta ttacgaatga acgtaaggct gtctatgact tttctgaccc
     8761 ttattataag acaggaattg cttgggcaac ggctaagaat tcaaagatta agtctttatc
     8821 tgacttaaaa ggtaagacgg ttgctttgaa gaccggtact gccggtgccg aatacgcgga
     8881 gtcaatcaag gaccagtacg gtttcaagat tacttacttc tctgattctg atacggttta
     8941 ccgcgatgtg attaatggta attcggttgc aacctttgcg gatatgcctg ttttgcagta
     9001 caccatcaaa aacggtactg ccttgaaggt tcaaaattca aaggacccat ttgctgcggg
     9061 tgacttaggt tttgccgtta agaaggggca aaatgccgaa ttgctagccg acttcaataa
     9121 gggtctagca atcattaaga agaacggtac ttacgataag attatcaaca agtacttgga
     9181 tgctaaggcg gagactttta cgggttctgc taaggataac agcacggttt ggggaatctt
     9241 gaagacaaac cgttcggcct tctggtctgg tttgaagcaa accatgtact tgacggttgt
     9301 cggtattatc ctcgcttccc tttggggctt gctgcttggt gtgatgggcg tgtcgaagaa
     9361 cgcttttgtt cgtggattgt ccacaacggt aatttatatt ttccgtggaa tgccaatgct
     9421 ggtcttggct ttcttcctat atattggaat tcctgccttg ttgggaacaa agatttctgc
     9481 ctggtcggcc ggaattttga ctttggtatt gaacgaagga gcctatacag gagcctttgt
     9541 ccggggagga ttccaatcag ttgattcagg acagatggaa gctgcccgtt cattgggatt
     9601 gtcacacggt caagcaatgc gaaaagtcat tatccctcag ggattgcgct tgatggtgcc
     9661 atcatttatt aaccagttta ttattacgtt gaaggatacg tcattattgt cagcaattgg
     9721 aatccttgaa ttaacacaaa ctggaacgtt gattgtcaca cgtaactcgc aaggtttccg
     9781 tgtttgggca atcgttgcta tgatatactt ggttgtaata acgttactga catggttcag
     9841 taactgggtt gaaaaaagga tgaacgcatg agtgaagaga aacaagtgaa agtacacgtt
     9901 gacaaggtca acaagtcata tggtgataac catgtcttac gcgatatttc cctggacgtc
     9961 atggataacg aagtggtcgt aatgattggc ccttctggtt ccggtaagtc gacgttcttg
    10021 cgaatgctca atcttctcga gaagccagac tctggtgtta tcgatgttga tggacatgat
    10081 atcttggatc caaagacgaa tatcaataag gttcgcgaaa atatcggaat ggttttccag
    10141 aactttaatc tcttcaataa ttacacggtt cttgaaaata tcaccttggc ccctgttcaa
    10201 ttgggcaaga tgacaaaggc cgaagccgaa gaaaaggcaa aggaattgct tgaaacggtt
    10261 ggtttgccag acaaggcgaa tgtttctgtc aattcgcttt ctggtggaca aaagcaacgt
    10321 gttgcgattg cccgtgcttt ggcaatgaat cctgacatca tgctttttga tgaaccaaca
    10381 tctgccttgg atccagaaat ggttggggat gttttggaag ttatgaagcg tttggctaag
//
