LOCUS       c00008_NZ_FOLI..       12163 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FOLI01000002.1 Fructobacillus durionis strain DSM 19113, whole
            genome shotgun sequence.
ACCESSION   NZ_FOLI01000002
VERSION     NZ_FOLI01000002
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:27
            Original ID  :: NZ_FOLI01000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 38983
            Orig. end    :: 51146
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12163
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[43983:46146](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7163
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12163
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12163
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             487..1548
                     /locus_tag="ctg8_43"
                     /transl_table=11
                     /translation="MTEAPHYQLSDFDYDLPEELIAQTPLKDRSSSRLLVLNALTGAYE
                     DKHFYDIIDYLNPGDALVMNNSRVLPARLHGIRPTTGGHAEVLLLRQDHDDVWEVLVKP
                     AKKSPVGSTIVFGDDPENPVMTGTIVKELEHGGRYIEFSYQGIFMERLEELGEMPLPPY
                     IKEKLDDQERYQTVYSKVDGSAAAPTAGLHWTPELLQKVADKGVELVELTLHVGLGTFR
                     PVDEENIEDHKMHSEFYQLSEEAAEKLNKVRANGGRVVATGTTSIRTLETIGTKFHGDL
                     KADSGWTDIFIKPGYDWQVVDAFITNFHLPKSTLVMLVAAFTGRDNILNAYKHAVADKY
                     RFFSFGDAMFVHK"
     aSDomain        508..1539
                     /aSDomain="TIGR00113"
                     /aSTool="tigrfam"
                     /description="queA: S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_43_0001"
                     /evalue="7.00E-133"
                     /identifier="TIGR00113"
                     /label="ctg8_43"
                     /locus_tag="ctg8_43"
                     /protein_end="351"
                     /protein_start="7"
                     /score="440.8"
                     /tool="antismash"
                     /translation="QLSDFDYDLPEELIAQTPLKDRSSSRLLVLNALTGAYEDKHFYDI
                     IDYLNPGDALVMNNSRVLPARLHGIRPTTGGHAEVLLLRQDHDDVWEVLVKPAKKSPVG
                     STIVFGDDPENPVMTGTIVKELEHGGRYIEFSYQGIFMERLEELGEMPLPPYIKEKLDD
                     QERYQTVYSKVDGSAAAPTAGLHWTPELLQKVADKGVELVELTLHVGLGTFRPVDEENI
                     EDHKMHSEFYQLSEEAAEKLNKVRANGGRVVATGTTSIRTLETIGTKFHGDLKADSGWT
                     DIFIKPGYDWQVVDAFITNFHLPKSTLVMLVAAFTGRDNILNAYKHAVADKYRFFSFGD
                     AMFV"
     PFAM_domain     511..1539
                     /aSDomain="Queuosine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02547.17"
                     /description="Queuosine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_43_0001"
                     /evalue="1.30E-135"
                     /label="ctg8_43"
                     /locus_tag="ctg8_43"
                     /protein_end="351"
                     /protein_start="8"
                     /score="451.8"
                     /tool="antismash"
                     /translation="LSDFDYDLPEELIAQTPLKDRSSSRLLVLNALTGAYEDKHFYDII
                     DYLNPGDALVMNNSRVLPARLHGIRPTTGGHAEVLLLRQDHDDVWEVLVKPAKKSPVGS
                     TIVFGDDPENPVMTGTIVKELEHGGRYIEFSYQGIFMERLEELGEMPLPPYIKEKLDDQ
                     ERYQTVYSKVDGSAAAPTAGLHWTPELLQKVADKGVELVELTLHVGLGTFRPVDEENIE
                     DHKMHSEFYQLSEEAAEKLNKVRANGGRVVATGTTSIRTLETIGTKFHGDLKADSGWTD
                     IFIKPGYDWQVVDAFITNFHLPKSTLVMLVAAFTGRDNILNAYKHAVADKYRFFSFGDA
                     MFV"
     CDS             1636..2091
                     /locus_tag="ctg8_44"
                     /transl_table=11
                     /translation="MKKYESKNAKETQALAEQIANLAQPGLVITLNGDLGAGKTTFTKG
                     FAQALGVEDRVKSPTFNILNTYESGRIPLYHFDAYRLEESGAADQGFEDYLGTDGVTLI
                     EWPQFMADLLPNDRLVMTFERTGESESDRVITVKGLGSAASIEEDLS"
     PFAM_domain     1654..2016
                     /aSDomain="TsaE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02367.19"
                     /description="Threonylcarbamoyl adenosine biosynthesis
                     protein TsaE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_44_0002"
                     /evalue="4.20E-39"
                     /label="ctg8_44"
                     /locus_tag="ctg8_44"
                     /protein_end="127"
                     /protein_start="6"
                     /score="133.5"
                     /tool="antismash"
                     /translation="KNAKETQALAEQIANLAQPGLVITLNGDLGAGKTTFTKGFAQALG
                     VEDRVKSPTFNILNTYESGRIPLYHFDAYRLEESGAADQGFEDYLGTDGVTLIEWPQFM
                     ADLLPNDRLVMTFERTG"
     aSDomain        1657..2046
                     /aSDomain="TIGR00150"
                     /aSTool="tigrfam"
                     /description="T6A_YjeE: tRNA threonylcarbamoyl adenosine
                     modification protein YjeE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_44_0002"
                     /evalue="4.60E-38"
                     /identifier="TIGR00150"
                     /label="ctg8_44"
                     /locus_tag="ctg8_44"
                     /protein_end="137"
                     /protein_start="7"
                     /score="128.1"
                     /tool="antismash"
                     /translation="NAKETQALAEQIANLAQPGLVITLNGDLGAGKTTFTKGFAQALGV
                     EDRVKSPTFNILNTYESGRIPLYHFDAYRLEESGAADQGFEDYLGTDGVTLIEWPQFMA
                     DLLPNDRLVMTFERTGESESDRVITV"
     CDS             2088..2645
                     /locus_tag="ctg8_45"
                     /transl_table=11
                     /translation="MMAEKRDGDEVTLTYSLKGMDLSNAQAAQDLLAVLKQESDTFLLA
                     DELARQQSQSFDEDDLDPEDDLPAKSWLIWAEAESDADSADNPAVSYPVGIGSISAGEV
                     GIAVLNDYQNQGLGRLTIEAMIDWAEQVGYDRLWLDVDVSNAPARHLYDELGFEVQPGD
                     EQEVKLPNGRVAELERRELSLA"
     PFAM_domain     2394..2558
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_45_0003"
                     /evalue="1.80E-13"
                     /label="ctg8_45"
                     /locus_tag="ctg8_45"
                     /protein_end="157"
                     /protein_start="102"
                     /score="50.8"
                     /tool="antismash"
                     /translation="EVGIAVLNDYQNQGLGRLTIEAMIDWAEQVGYDRLWLDVDVSNAP
                     ARHLYDELGF"
     CDS             2642..3175
                     /locus_tag="ctg8_46"
                     /transl_table=11
                     /translation="MNFVAIDFETASGQRHSAVSLALVVVRDDKIVDQFYTLLKPDTHF
                     SARNSQIHGIYEKDVVDAPTFKNIWPTIAPFFTEDKLVVAHNATFDVSVLKACLDYYDL
                     PDAHFQVLDTLRTSRKLMPDLPNHKLNTVSASLDISLKNHHNALADAVACAEILIRQGQ
                     LFGTAPLKQAVRYK"
     aSDomain        2648..3118
                     /aSDomain="TIGR00573"
                     /aSTool="tigrfam"
                     /description="dnaq: exonuclease, DNA polymerase III,
                     epsilon subunit family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_46_0003"
                     /evalue="3.80E-24"
                     /identifier="TIGR00573"
                     /label="ctg8_46"
                     /locus_tag="ctg8_46"
                     /protein_end="159"
                     /protein_start="2"
                     /score="83.3"
                     /tool="antismash"
                     /translation="FVAIDFETASGQRHSAVSLALVVVRDDKIVDQFYTLLKPDTHFSA
                     RNSQIHGIYEKDVVDAPTFKNIWPTIAPFFTEDKLVVAHNATFDVSVLKACLDYYDLPD
                     AHFQVLDTLRTSRKLMPDLPNHKLNTVSASLDISLKNHHNALADAVACAEILI"
     PFAM_domain     2651..3115
                     /aSDomain="RNase_T"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00929.26"
                     /description="Exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_46_0004"
                     /evalue="2.90E-22"
                     /label="ctg8_46"
                     /locus_tag="ctg8_46"
                     /protein_end="158"
                     /protein_start="3"
                     /score="80.1"
                     /tool="antismash"
                     /translation="VAIDFETASGQRHSAVSLALVVVRDDKIVDQFYTLLKPDTHFSAR
                     NSQIHGIYEKDVVDAPTFKNIWPTIAPFFTEDKLVVAHNATFDVSVLKACLDYYDLPDA
                     HFQVLDTLRTSRKLMPDLPNHKLNTVSASLDISLKNHHNALADAVACAEIL"
     CDS             3400..3573
                     /locus_tag="ctg8_47"
                     /transl_table=11
                     /translation="MYELSLNDKVLSNHELENINGGLFPIVIAGMVITGKSAAWGAGAL
                     AAGAATGYLLNR"
     aSDomain        3424..3465
                     /aSDomain="TIGR01847"
                     /aSTool="tigrfam"
                     /description="bacteriocin_sig: bacteriocin-type signal
                     sequence"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_47_0005"
                     /evalue="2.60E-03"
                     /identifier="TIGR01847"
                     /label="ctg8_47"
                     /locus_tag="ctg8_47"
                     /protein_end="22"
                     /protein_start="8"
                     /score="16.3"
                     /tool="antismash"
                     /translation="KVLSNHELENINGG"
     aSDomain        3424..3558
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_47_0004"
                     /evalue="9.60E-10"
                     /identifier="TIGR03949"
                     /label="ctg8_47"
                     /locus_tag="ctg8_47"
                     /protein_end="53"
                     /protein_start="8"
                     /score="36.1"
                     /tool="antismash"
                     /translation="KVLSNHELENINGGLFPIVIAGMVITGKSAAWGAGALAAGAATGY
                     "
     CDS             3583..3735
                     /locus_tag="ctg8_48"
                     /transl_table=11
                     /translation="MNVNNAIMEKKYLLTDKELSDVNGGIAPGILLGLYMAGYTMGKDF
                     ASRKR"
     aSDomain        3622..3708
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_48_0006"
                     /evalue="1.60E-08"
                     /identifier="TIGR03949"
                     /label="ctg8_48"
                     /locus_tag="ctg8_48"
                     /protein_end="42"
                     /protein_start="13"
                     /score="32.2"
                     /tool="antismash"
                     /translation="LTDKELSDVNGGIAPGILLGLYMAGYTMG"
     CDS             complement(3994..4761)
                     /locus_tag="ctg8_49"
                     /transl_table=11
                     /translation="MQRNFILELRKKHSLSQQEFADLIFVSRQLVSNWEQDKSEPSLEN
                     KKLIATLFNMDIDELDVYNKNNHLKNSEIKKEKIKQAFLQSLVRTQNTLETLQDIAKES
                     NLKKNEVQLYFLNSEDVLIDIIKNIEKSIYIQLNHSLHEQSDSLARVQNRIFPVLYQQQ
                     DNIRILYQNAISRAYWNEVLENVFNQIIDKELQQRQLTHLLIDRSFQIYLVSRQLMSFI
                     ETWMRHPTSPSLRDIQLLFKQFSYYSTKILLEN"
     PFAM_domain     complement(4582..4746)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_49_0005"
                     /evalue="4.70E-11"
                     /label="ctg8_49"
                     /locus_tag="ctg8_49"
                     /protein_end="60"
                     /protein_start="5"
                     /score="42.7"
                     /tool="antismash"
                     /translation="ILELRKKHSLSQQEFADLIFVSRQLVSNWEQDKSEPSLENKKLIA
                     TLFNMDIDEL"
     CDS             5001..7163
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 289.9; E-value:
                     6.7e-88)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_50"
                     /sec_met_domain="TIGR01193 (E-value: 4.4e-274, bitscore:
                     904.5, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.5e-40, bitscore:
                     131.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VFFKYISQVDERDCGVACLAMVLKSYKHIVSIARLRELAKTNLEG
                     TTALGIKRAAEKENFTVQAVQANMTLFDEYKKLPLPFIIHVQKPDKGQIVEHYYVIYKV
                     GHNRIYIADPDPNVKKMAMSYVEISKQWTGVALFFAPNPEFSPEKMHDSYLSSIFSIMK
                     KYKGLIVNTVIAALFVTLVGVVGSYFVQLLVDEYVPNSMTSTLTIVSCGLIIAYSFQQI
                     MSYTEQYLLIVIGQRLSIDLILSYIKHLFQLPMSFFYNRRIGELTSRFNDANSVIEAIA
                     SSILSLLIDVIVVLMMAIILLNYNAQLFLITILSIPIYCIIIMLFVKKFSRLNHEVMSA
                     GANLEASIIERLKGMETVKALGAEQKSYGSIDHDYVVFLTKSFLKEKAIAIQEAVKGLI
                     KLMLQVIILWVGAQLVIKGEMTIGKLMAYNALLSYFTDPLQSIINLQSKIQMAMVAAHR
                     LQEVYEVQSEFQLNDESFTLSAEKIEIEFKSLSFGYQYNHSIFNHLDLLIKANQKVALV
                     GSTGSGKSTLVKLLIRFFEVENGSGEIRINGHNIKHVNKESLRSIISYVPQESQFFSGK
                     IIDNLLLGVESEIDINDVFKACEMVEIRADIEAMPNGFFTELSDTTTLSGGQKQRLAIA
                     RVLLRNSKVLILDESTSNLDRLTEKKVISRLMAIQDKTIIFVAHRLTIAEYAERVVMLE
                     KGNVVADGSHGLLLKSNKHYQTLVQK"
     PFAM_domain     5007..5429
                     /aSDomain="Peptidase_C39"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03412.17"
                     /description="Peptidase C39 family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_50_0006"
                     /evalue="1.80E-38"
                     /label="ctg8_50"
                     /locus_tag="ctg8_50"
                     /protein_end="143"
                     /protein_start="2"
                     /score="131.4"
                     /tool="antismash"
                     /translation="FKYISQVDERDCGVACLAMVLKSYKHIVSIARLRELAKTNLEGTT
                     ALGIKRAAEKENFTVQAVQANMTLFDEYKKLPLPFIIHVQKPDKGQIVEHYYVIYKVGH
                     NRIYIADPDPNVKKMAMSYVEISKQWTGVALFFAPNP"
     aSDomain        5022..7157
                     /aSDomain="TIGR01193"
                     /aSTool="tigrfam"
                     /description="bacteriocin_ABC: ABC-type bacteriocin
                     transporter"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_50_0007"
                     /evalue="1.20E-272"
                     /identifier="TIGR01193"
                     /label="ctg8_50"
                     /locus_tag="ctg8_50"
                     /protein_end="719"
                     /protein_start="7"
                     /score="904.5"
                     /tool="antismash"
                     /translation="QVDERDCGVACLAMVLKSYKHIVSIARLRELAKTNLEGTTALGIK
                     RAAEKENFTVQAVQANMTLFDEYKKLPLPFIIHVQKPDKGQIVEHYYVIYKVGHNRIYI
                     ADPDPNVKKMAMSYVEISKQWTGVALFFAPNPEFSPEKMHDSYLSSIFSIMKKYKGLIV
                     NTVIAALFVTLVGVVGSYFVQLLVDEYVPNSMTSTLTIVSCGLIIAYSFQQIMSYTEQY
                     LLIVIGQRLSIDLILSYIKHLFQLPMSFFYNRRIGELTSRFNDANSVIEAIASSILSLL
                     IDVIVVLMMAIILLNYNAQLFLITILSIPIYCIIIMLFVKKFSRLNHEVMSAGANLEAS
                     IIERLKGMETVKALGAEQKSYGSIDHDYVVFLTKSFLKEKAIAIQEAVKGLIKLMLQVI
                     ILWVGAQLVIKGEMTIGKLMAYNALLSYFTDPLQSIINLQSKIQMAMVAAHRLQEVYEV
                     QSEFQLNDESFTLSAEKIEIEFKSLSFGYQYNHSIFNHLDLLIKANQKVALVGSTGSGK
                     STLVKLLIRFFEVENGSGEIRINGHNIKHVNKESLRSIISYVPQESQFFSGKIIDNLLL
                     GVESEIDINDVFKACEMVEIRADIEAMPNGFFTELSDTTTLSGGQKQRLAIARVLLRNS
                     KVLILDESTSNLDRLTEKKVISRLMAIQDKTIIFVAHRLTIAEYAERVVMLEKGNVVAD
                     GSHGLLLKSNKHYQTLVQ"
     PFAM_domain     5514..6317
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_50_0007"
                     /evalue="2.90E-51"
                     /label="ctg8_50"
                     /locus_tag="ctg8_50"
                     /protein_end="439"
                     /protein_start="171"
                     /score="174.8"
                     /tool="antismash"
                     /translation="TVIAALFVTLVGVVGSYFVQLLVDEYVPNSMTSTLTIVSCGLIIA
                     YSFQQIMSYTEQYLLIVIGQRLSIDLILSYIKHLFQLPMSFFYNRRIGELTSRFNDANS
                     VIEAIASSILSLLIDVIVVLMMAIILLNYNAQLFLITILSIPIYCIIIMLFVKKFSRLN
                     HEVMSAGANLEASIIERLKGMETVKALGAEQKSYGSIDHDYVVFLTKSFLKEKAIAIQE
                     AVKGLIKLMLQVIILWVGAQLVIKGEMTIGKLMAYNALLSYFTDPL"
     PFAM_domain     6504..6956
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_50_0008"
                     /evalue="1.80E-30"
                     /label="ctg8_50"
                     /locus_tag="ctg8_50"
                     /protein_end="652"
                     /protein_start="501"
                     /score="106.3"
                     /tool="antismash"
                     /translation="NHLDLLIKANQKVALVGSTGSGKSTLVKLLIRFFEVENGSGEIRI
                     NGHNIKHVNKESLRSIISYVPQESQFFSGKIIDNLLLGVESEIDINDVFKACEMVEIRA
                     DIEAMPNGFFTELSDTTTLSGGQKQRLAIARVLLRNSKVLILDESTS"
     CDS             7177..8280
                     /locus_tag="ctg8_51"
                     /transl_table=11
                     /translation="LNDEMKFESAEFYHRRFGSFATKIIWPIVTVFIISILILFITKKE
                     ITVKSVGKIIPGEAILKIYSNAEGVIIENNLSENKVVHTGETLLKLSNPSMKINLKNNI
                     QKQKEIQKQKEELEGYKNSVESNKKPFSVSNHYGYEELFAEYQNHINEVDRQNQNNIDE
                     INKMDLSIEERNKKIAQCHESFSQEKMGLKLKTLAGIKQDIQGIKNKIIGLKGEYEFLN
                     SNMEHLTVRAPEDGILHLKNSNFKSKSISLGTEVADVYPKINKKNKLIIQFFVPANKMN
                     ELKVKQSVRFKANQTGPTPLVATGSIRSIQVAPTETESGSLYQVQALIQTESKDISKVR
                     YGLEGRVSVITGKITWFNYLRNLIFND"
     PFAM_domain     7861..8181
                     /aSDomain="HlyD_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13437.8"
                     /description="HlyD family secretion protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_51_0009"
                     /evalue="2.50E-09"
                     /label="ctg8_51"
                     /locus_tag="ctg8_51"
                     /protein_end="335"
                     /protein_start="228"
                     /score="37.8"
                     /tool="antismash"
                     /translation="TVRAPEDGILHLKNSNFKSKSISLGTEVADVYPKINKKNKLIIQF
                     FVPANKMNELKVKQSVRFKANQTGPTPLVATGSIRSIQVAPTETESGSLYQVQALIQTE
                     SKD"
     CDS             8646..8813
                     /locus_tag="ctg8_52"
                     /transl_table=11
                     /translation="MDSNGFQIMEEYELAKVNGGIFPIVIGGVLITKGAAIGAGCFTAG
                     IGAGLYLGLR"
     aSDomain        8661..8792
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_52_0008"
                     /evalue="6.40E-07"
                     /identifier="TIGR03949"
                     /label="ctg8_52"
                     /locus_tag="ctg8_52"
                     /protein_end="49"
                     /protein_start="5"
                     /score="27.0"
                     /tool="antismash"
                     /translation="FQIMEEYELAKVNGGIFPIVIGGVLITKGAAIGAGCFTAGIGAG"
     CDS             8829..8984
                     /locus_tag="ctg8_53"
                     /transl_table=11
                     /translation="MTINLKDENLINVTGGKRYYKVSGKSVAMGAGLFTGGFELGYKIG
                     KAMRRK"
     CDS             complement(9252..9953)
                     /NRPS_PKS="Domain: oMT (71-186). E-value: 3.5e-09. Score:
                     27.0. Matches aSDomain: nrpspksdomains_ctg8_54_oMT.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 74; E-value: 2.1e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_54"
                     /transl_table=11
                     /translation="MKKGVDAPYALFGMTFAAILFCFQAIRTNNLIFWISTIVLSFSAV
                     TYFHTTYFGKYKIIEAAVRRLHIKTDNQILDLGTGHGIVLTEVAKYLKVPGKATGIDIW
                     RSSDQSNNSSESATSNIHRLGYEKVANVMTANMLALPFPDNSFDIITASLSIHNLKSNT
                     ERAIALTEATRVLKPNGKLLIIDLKYAREYQETLLHSNQFTTVQSVKNGYNGWWGGPWM
                     ATTIITAQKNK"
     aSDomain        complement(9396..9740)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_54_oMT.1"
                     /domain_subtype="oMT"
                     /evalue="3.50E-09"
                     /label="ctg8_54_oMT.1"
                     /locus_tag="ctg8_54"
                     /protein_end="186"
                     /protein_start="71"
                     /score="27.0"
                     /tool="antismash"
                     /translation="NQILDLGTGHGIVLTEVAKYLKVPGKATGIDIWRSSDQSNNSSES
                     ATSNIHRLGYEKVANVMTANMLALPFPDNSFDIITASLSIHNLKSNTERAIALTEATRV
                     LKPNGKLLIID"
     PFAM_domain     complement(9402..9731)
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_54_0010"
                     /evalue="1.90E-17"
                     /label="ctg8_54"
                     /locus_tag="ctg8_54"
                     /protein_end="184"
                     /protein_start="74"
                     /score="63.7"
                     /tool="antismash"
                     /translation="LDLGTGHGIVLTEVAKYLKVPGKATGIDIWRSSDQSNNSSESATS
                     NIHRLGYEKVANVMTANMLALPFPDNSFDIITASLSIHNLKSNTERAIALTEATRVLKP
                     NGKLLI"
     CDS             complement(10072..10890)
                     /locus_tag="ctg8_55"
                     /transl_table=11
                     /translation="MKLISWNIDSINAAVEHKSDRGLMTWGVLEGIAAKQPDVVAIQET
                     KLKVDGMTKKQKEALEGLFPGYHFYANSSSARKSYAGTMLITKDEPIMVDFPAIGAPGE
                     MDQEGRIVTAEFEDCYVSTVYTPNAGGELARLDDRQLWDDAYRNYIDGLNEKKPVIFSG
                     DFNVAHEEIDLKHPKQNHHSAGFTDEEREHFTKLLDAGYTDTLRAMYPDQPDIYSWWAQ
                     RSKTSKINNSGWRIDYYLVSNRIADKVEDIHVVDTGARQDHAPLELDIKM"
     aSDomain        complement(10081..10890)
                     /aSDomain="TIGR00633"
                     /aSTool="tigrfam"
                     /description="xth: exodeoxyribonuclease III (xth)"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_55_0009"
                     /evalue="2.60E-77"
                     /identifier="TIGR00633"
                     /label="ctg8_55"
                     /locus_tag="ctg8_55"
                     /protein_end="270"
                     /protein_start="0"
                     /score="257.8"
                     /tool="antismash"
                     /translation="MKLISWNIDSINAAVEHKSDRGLMTWGVLEGIAAKQPDVVAIQET
                     KLKVDGMTKKQKEALEGLFPGYHFYANSSSARKSYAGTMLITKDEPIMVDFPAIGAPGE
                     MDQEGRIVTAEFEDCYVSTVYTPNAGGELARLDDRQLWDDAYRNYIDGLNEKKPVIFSG
                     DFNVAHEEIDLKHPKQNHHSAGFTDEEREHFTKLLDAGYTDTLRAMYPDQPDIYSWWAQ
                     RSKTSKINNSGWRIDYYLVSNRIADKVEDIHVVDTGARQDHAPLELDI"
     aSDomain        complement(10084..10890)
                     /aSDomain="TIGR00195"
                     /aSTool="tigrfam"
                     /description="exoDNase_III: exodeoxyribonuclease III"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_55_0010"
                     /evalue="1.40E-63"
                     /identifier="TIGR00195"
                     /label="ctg8_55"
                     /locus_tag="ctg8_55"
                     /protein_end="269"
                     /protein_start="0"
                     /score="212.8"
                     /tool="antismash"
                     /translation="MKLISWNIDSINAAVEHKSDRGLMTWGVLEGIAAKQPDVVAIQET
                     KLKVDGMTKKQKEALEGLFPGYHFYANSSSARKSYAGTMLITKDEPIMVDFPAIGAPGE
                     MDQEGRIVTAEFEDCYVSTVYTPNAGGELARLDDRQLWDDAYRNYIDGLNEKKPVIFSG
                     DFNVAHEEIDLKHPKQNHHSAGFTDEEREHFTKLLDAGYTDTLRAMYPDQPDIYSWWAQ
                     RSKTSKINNSGWRIDYYLVSNRIADKVEDIHVVDTGARQDHAPLELD"
     PFAM_domain     complement(10159..10878)
                     /aSDomain="Exo_endo_phos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03372.25"
                     /description="Endonuclease/Exonuclease/phosphatase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_55_0011"
                     /evalue="3.10E-12"
                     /label="ctg8_55"
                     /locus_tag="ctg8_55"
                     /protein_end="244"
                     /protein_start="4"
                     /score="46.7"
                     /tool="antismash"
                     /translation="SWNIDSINAAVEHKSDRGLMTWGVLEGIAAKQPDVVAIQETKLKV
                     DGMTKKQKEALEGLFPGYHFYANSSSARKSYAGTMLITKDEPIMVDFPAIGAPGEMDQE
                     GRIVTAEFEDCYVSTVYTPNAGGELARLDDRQLWDDAYRNYIDGLNEKKPVIFSGDFNV
                     AHEEIDLKHPKQNHHSAGFTDEEREHFTKLLDAGYTDTLRAMYPDQPDIYSWWAQRSKT
                     SKINNSGWRIDYYLVSNR"
     CDS             complement(10912..11772)
                     /locus_tag="ctg8_56"
                     /transl_table=11
                     /translation="MIQLSQKIAANVIQPRKSQSYKGTYGRVLIIGGNANLGGAVIMNA
                     QAAVQSGAGLVTVATDFSNKTAIHARLPEAMVVDYHDHLADYIQKADVVLIGSGLGEEV
                     DILKTCLKAVQENQIVIIDGSAITMMAEHNLDLPKAQVVLTPHQMEWQRLGEVAIADQS
                     REDNNWEALVSFHPEPILVLKSNATQVYLEHELYQLSVGGPYQATGGMGDTLAGMIAGF
                     TAQFHPLGPAVLSAVYCHSAIAAELSKSAYVTLPSKIAEAIPAYMNKLADMPLSATGLD
                     EEQEE"
     aSDomain        complement(10969..11751)
                     /aSDomain="TIGR00196"
                     /aSTool="tigrfam"
                     /description="yjeF_cterm: YjeF family C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_56_0011"
                     /evalue="4.60E-47"
                     /identifier="TIGR00196"
                     /label="ctg8_56"
                     /locus_tag="ctg8_56"
                     /protein_end="268"
                     /protein_start="7"
                     /score="158.6"
                     /tool="antismash"
                     /translation="IAANVIQPRKSQSYKGTYGRVLIIGGNANLGGAVIMNAQAAVQSG
                     AGLVTVATDFSNKTAIHARLPEAMVVDYHDHLADYIQKADVVLIGSGLGEEVDILKTCL
                     KAVQENQIVIIDGSAITMMAEHNLDLPKAQVVLTPHQMEWQRLGEVAIADQSREDNNWE
                     ALVSFHPEPILVLKSNATQVYLEHELYQLSVGGPYQATGGMGDTLAGMIAGFTAQFHPL
                     GPAVLSAVYCHSAIAAELSKSAYVTLPSKIAEAIPAYMN"
     PFAM_domain     complement(10981..11691)
                     /aSDomain="Carb_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01256.19"
                     /description="Carbohydrate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_56_0012"
                     /evalue="1.30E-53"
                     /label="ctg8_56"
                     /locus_tag="ctg8_56"
                     /protein_end="264"
                     /protein_start="27"
                     /score="182.1"
                     /tool="antismash"
                     /translation="VLIIGGNANLGGAVIMNAQAAVQSGAGLVTVATDFSNKTAIHARL
                     PEAMVVDYHDHLADYIQKADVVLIGSGLGEEVDILKTCLKAVQENQIVIIDGSAITMMA
                     EHNLDLPKAQVVLTPHQMEWQRLGEVAIADQSREDNNWEALVSFHPEPILVLKSNATQV
                     YLEHELYQLSVGGPYQATGGMGDTLAGMIAGFTAQFHPLGPAVLSAVYCHSAIAAELSK
                     SAYVTLPSKIAEAIP"
ORIGIN
        1 cgagccggaa gatttggcgg agattgtcaa acgtacggcg gcgatttttg aggcaccaat
       61 tacgaaagag ggagccttgg ccgtggccct acgttcccgt gggacgccaa gaattgccaa
      121 ccgcttgtta aagcgggtgc gcgactttgc ccaggtggcc ggtaagacag cgattgaacc
      181 ggaactggtt gacatggcct tggataagct acgtgtcgat caaaagggct tggatgaaac
      241 cgaccacaag ttgctgctgt cgatgattga tttgtacaat ggtggaccgg ttggtctggc
      301 aacgattgcc gctaacattg gtgaagaaca ggacaccatt gaatcaatgg tcgaacccta
      361 cttgctacaa atcggttttt tgaaacggac acctcgtggc cgtgttgtga cagaggcggc
      421 ttacgagcac cttggtcgac catatcctga gaaataaatt tgataaatta aaaagggggg
      481 ccttccatga cggaagcacc acattaccaa ctatctgatt ttgactatga tttacctgaa
      541 gaattaattg cgcaaacacc tttgaaggac cgttcgtcat cccgtttgct ggttctgaac
      601 gctttgacgg gtgcttatga agacaagcat ttttacgaca tcattgatta tttgaacccg
      661 ggcgatgcct tggttatgaa taactcacgt gtcttgccag cccgtttgca cggtattcgt
      721 ccaacaactg gcgggcatgc cgaagtgctc ttgctccgtc aggatcacga cgatgtctgg
      781 gaagttttgg ttaagccagc gaaaaaatca ccggttggtt caaccattgt ctttggggat
      841 gacccagaga acccagtgat gactggtacc attgtcaagg aattggagca cggtggccgt
      901 tacatcgaat tcagttacca gggcatcttc atggaacgct tggaagaact tggtgaaatg
      961 ccactgcctc catatattaa ggaaaaactt gatgaccagg agcgctatca gaccgtttac
     1021 tcaaaggtgg atggttcagc ggctgcacca acggccggct tgcactggac gccggagctc
     1081 ttgcaaaaag tcgccgataa gggtgttgaa ttggtggaat tgactttgca cgttggacta
     1141 ggaaccttcc gtccggtgga cgaagaaaac attgaagatc ataagatgca ctccgagttc
     1201 taccagttgt cggaagaggc tgccgaaaag ttaaacaagg tgcgtgccaa cggtggccgt
     1261 gtggttgcca ctggtacgac ttcaattcgt accttggaaa caattggaac gaagttccat
     1321 ggtgacttaa aggcggattc tggctggact gatatcttca tcaaacctgg ctacgactgg
     1381 caggttgtgg acgccttcat tacgaacttc cacttgccaa agtcaaccct tgtgatgttg
     1441 gttgcggcct ttaccggtcg tgataacatc ttgaacgcct acaagcacgc ggtggcggat
     1501 aagtaccgtt tcttctcctt cggggatgcc atgttcgtgc ataaataaat gataaataaa
     1561 agcagccttt attggctgct ttttgcttga ttcggttcag accgtctctt tgtggaccat
     1621 gttataatag actctatgaa aaaatacgaa agcaaaaatg caaaagaaac ccaggccttg
     1681 gcagaacaga ttgccaacct tgcacagcct ggtttggtca ttaccttgaa cggtgacctc
     1741 ggggctggga agacgacttt tacgaaaggg tttgcccaag ctttgggggt tgaagaccgt
     1801 gtgaagagcc caacctttaa tatcttgaat acctacgaat ctggtcgaat tcctttgtac
     1861 cacttcgacg cctaccgttt ggaagaatcc ggtgcggctg accagggatt tgaagattac
     1921 ttgggaaccg atggggtcac tttgattgag tggccacagt ttatggcgga cttactacca
     1981 aacgaccgct tggtgatgac ctttgagcga acgggggagt ctgagtctga ccgtgtgatt
     2041 accgtcaagg gcctcggttc tgctgcaagt attgaagagg atttgtcatg atggcggaaa
     2101 agcgggatgg ggatgaagtg actttaacct atagtttaaa ggggatggac ctgtccaatg
     2161 ctcaggctgc tcaagattta ttagccgtgc tgaagcagga gtccgatacc tttttactag
     2221 ccgacgaatt ggctcgccaa cagtcccagt cctttgatga agatgacctg gacccagagg
     2281 acgatttacc ggcaaagtct tggttgattt gggcggaagc tgaatcggat gctgattcag
     2341 ctgataatcc tgctgtttct tatccggttg gcattggatc aatttcagct ggtgaagtgg
     2401 ggattgccgt tttgaatgac tatcagaacc aaggcttagg acgtctgacg attgaagcca
     2461 tgattgattg ggctgagcag gttgggtacg accggctctg gttggatgtt gacgttagca
     2521 atgcgccggc ccgtcatctt tacgatgaac tgggctttga agtacagcct ggggatgagc
     2581 aagaggtgaa gttacccaac ggacgggtgg cagaattaga gcgaagggag ttgagtctag
     2641 catgaacttt gtagcaattg actttgaaac ggcctctggc cagcggcatt ctgccgtttc
     2701 gctagctctt gttgttgttc gcgatgataa aattgttgac cagttttata ccctgttgaa
     2761 gccggataca catttttcgg ctcgcaactc acagattcat ggtatttacg aaaaagacgt
     2821 ggtggatgca ccgactttta aaaatatttg gccaacaatt gcacctttct ttaccgagga
     2881 taaattggta gtagcccaca atgcgacttt tgatgtatcc gtcttgaagg cctgcctgga
     2941 ctattacgac ctaccggatg cgcactttca ggtcttggat actttgcgca cttctcgtaa
     3001 gttaatgccg gacctaccta accataagtt gaatacggtt tcggcttcct tagacatctc
     3061 attgaagaac caccacaacg ccttagctga cgcggtggcc tgtgctgaga ttttaattcg
     3121 acagggtcaa ctctttggaa cggcaccatt gaagcaggcg gtaaggtata agtaatagta
     3181 ctcattcaaa ttaaaagcca ttcgttcgaa agaacggatg gcttttatga tgcaattgga
     3241 aaatacgtaa taaaaaatga gatgcacaag caatagttgg tgatgagttt gctatttatt
     3301 tagcagaatg tttctaagag cttgttatgc taaatgtgtt agctaacgca ttaaataatt
     3361 attagttgta ttttcggtta ataaaaagga gtgacactta tgtatgagtt aagtttaaac
     3421 gataaggtat tatcaaatca tgaattagag aatattaatg ggggcttatt tccaatcgta
     3481 attgctggaa tggtgattac tggaaagtca gcagcatggg gagctggagc tctggcggct
     3541 ggagcagcaa caggttattt gttaaacaga taggggaata atatgaacgt taataatgca
     3601 attatggaaa agaaatattt gttaactgat aaagagttat ctgacgttaa tggaggaatc
     3661 gcacccggaa ttttgttagg actctatatg gcaggatata cgatggggaa agattttgca
     3721 tcgcgaaaaa ggtaaaagtt tcaacttttt gattgccgta tttataattt atttgcttgc
     3781 tattatattg aatgatttaa attttatttc tttgcctagt attttagaaa aatcttatgg
     3841 tggctttctg gtgatttata tatgttgtat tactatccaa gagtctaata atgtaagcgg
     3901 taaacggtaa ttgttaaata tattttttca aattcttggt tattaatcta aaaaaagctt
     3961 ctcaatttat ttgagaagct tttttaagaa tgattaattt tctaatagaa ttttagttga
     4021 ataatagctg aattgtttaa aaagtaattg aatatctctt aaagatgggg aagttggatg
     4081 acgcatccat gtttcgataa aagacattag ttgacgagat actaaatata tttgaaaaga
     4141 ccgatcaatt agtagatgag tcaactgtcg ttgttgtaat tctttgtcaa ttatttggtt
     4201 aaaaacattc tcgagtactt cattccaata tgctcgtgaa attgcatttt gatataaaat
     4261 ccggatatta tcttgttgtt gataaaggac ggggaaaatt cggttttgta ctctagctaa
     4321 ggaatctgac tgctcatgaa gcgaatgatt taattgtatg taaatgcttt tctcaatgtt
     4381 tttaatgatg tcgattagaa catcttcact gtttaaaaag tacaattgta cttcattctt
     4441 ttttaggtta ctttccttag cgatatcttg tagagtttct aaagtatttt gtgtacggac
     4501 tagtgattgt aaaaaagcct gttttatttt ttctttttta atttctgagt tttttaaatg
     4561 attattttta ttgtatacat ccaattcatc tatatccatg ttaaataatg tggcaattaa
     4621 ttttttattc tctagactag gttcactttt atcttgttcc cagtttgaaa ccaattgtct
     4681 cgaaacaaat attaaatcag caaattcttg ttgtgacaac gagtgctttt ttcgtaattc
     4741 taaaataaag tttctttgca tcactatgct ccttttaaac ggggctgaat cttacataag
     4801 catgagaact actaattttt ttaaagttat cattttaagt ttggacaggc aagataaaat
     4861 tggtgtttgc ttgctatttt tttagcaatt cttagttatt tttcttgtta tattttgggt
     4921 gccttaaaac agaagataaa aattataagc aatataaaaa agtaaatact ggtttgtatt
     4981 agtgaaaaac ggaggaaaga gtgtttttta aatatatttc ccaagtggat gaacgagatt
     5041 gtggtgttgc ttgtttagct atggtactaa aatcatataa acatattgta tccattgccc
     5101 ggttacggga attagcaaag actaatttgg agggaacaac tgcactcggc attaaacgtg
     5161 cagccgagaa agaaaatttt accgttcaag cagttcaagc aaacatgaca ttatttgatg
     5221 aatataaaaa attacctttg ccctttatca ttcacgttca aaaacctgat aaagggcaaa
     5281 ttgtagaaca ttactatgtt atttataagg ttggccacaa ccgaatatat attgcagatc
     5341 ctgatccgaa tgtaaaaaaa atggcaatgt catatgtcga aatttcgaaa cagtggacag
     5401 gagttgcatt gttttttgct cctaatccag agtttagtcc agaaaaaatg catgatagtt
     5461 atttgtcatc aattttttcg attatgaaaa agtacaaagg tttgattgtt aatacagtga
     5521 tagctgcttt atttgtcact cttgtaggcg ttgtgggttc atattttgtc cagttattag
     5581 tcgatgaata tgtgccaaat agtatgacaa gtacattaac aatagtgagt tgtggattaa
     5641 tcattgcata cagttttcaa caaataatgt cctatactga acaatatctt ttgatagtta
     5701 tagggcaacg tttatcaatt gatttgattc tttcttatat caaacacctt ttccaactgc
     5761 caatgagttt tttttataat cgaagaattg gggagttaac ttcacgtttt aatgatgcta
     5821 attcagttat tgaagcaata gcttcttcga ttctttcact acttattgat gtgattgtag
     5881 ttttaatgat ggcaattatt ttattaaatt acaatgcaca gcttttttta ataacaatat
     5941 tatctattcc gatttattgc ataattatta tgctttttgt taaaaagttt tcgcgattaa
     6001 accatgaagt gatgagtgct ggagctaatt tggaagcttc aattattgaa cgcttgaagg
     6061 gaatggaaac cgttaaggct ttgggggctg aacaaaaaag ctatggaagc attgatcatg
     6121 attatgttgt ttttttgaca aaatcttttt tgaaagaaaa agctatagca attcaagaag
     6181 cagttaaagg gttaataaaa ttaatgttgc aagtcattat tttatgggtt ggtgctcaac
     6241 tagtgattaa gggtgagatg acgattggaa aattaatggc ctataatgct ttactaagtt
     6301 attttactga tccattacag tcaatcatta atttacaaag taaaatccaa atggccatgg
     6361 ttgctgctca tcgattacaa gaagtgtatg aggtgcaatc tgaatttcaa ttaaatgatg
     6421 aatctttcac attaagtgca gaaaaaatag aaattgaatt taagtctctt tcatttggat
     6481 atcaatataa tcactcaatt tttaaccacc ttgatttatt aattaaagcc aatcaaaaag
     6541 tagctttagt tggatcaaca ggatctggaa aatcgacttt agtaaagtta ttaattcgtt
     6601 tttttgaagt ggaaaatgga agtggggaaa ttaggataaa tggtcataac attaaacacg
     6661 ttaataagga atcacttcgt tcgattattt cttacgttcc acaagaatcg cagttctttt
     6721 ctggaaaaat tattgataat ttacttttag gcgtagaaag tgaaattgat attaatgatg
     6781 ttttcaaagc ttgcgaaatg gttgagatac gagctgatat tgaggcaatg ccaaatggtt
     6841 ttttcactga actgtcagat actactacac tttctggagg gcagaagcaa aggctagcga
     6901 tagctcgagt actattgaga aattctaaag tactaatttt agatgaatca accagtaact
     6961 tagatcgact gacagaaaaa aaggttatta gccgattaat ggctattcaa gacaaaacta
     7021 tcatttttgt agcccatcgt ttaaccattg ctgaatacgc tgaaagagtc gtaatgttag
     7081 agaagggaaa tgttgtggca gacgggtcgc acggtttatt acttaaaagt aataaacact
     7141 atcagacgct agttcaaaaa taagtgaggt ggttttttga acgatgaaat gaaatttgag
     7201 agtgctgagt tttatcatcg tcggtttgga agttttgcaa caaagataat ttggccaatt
     7261 gttacagtgt tcattatttc aattcttatt ttatttatta ctaaaaagga aataactgtt
     7321 aagtcagtgg gtaaaatcat tccgggagaa gcaattttga aaatctattc caatgcagaa
     7381 ggtgtgatta ttgaaaataa tttgagtgaa aataaagtgg tccatacggg tgagacttta
     7441 ttgaaattat ctaatccatc aatgaaaatt aatttgaaaa ataatataca gaaacaaaag
     7501 gaaattcaga aacaaaaaga ggagttagag ggttataaaa atagtgtcga atcgaataag
     7561 aaaccctttt cagttagtaa tcattatggt tatgaggagc tatttgctga atatcaaaac
     7621 catataaatg aagtcgatag acaaaaccaa aataatattg atgaaattaa caaaatggat
     7681 ttgagtatcg aagagagaaa caaaaagata gcacaatgtc atgaatcatt ttctcaagaa
     7741 aagatgggct tgaaactaaa aacattggca ggaattaaac aagatattca aggtataaaa
     7801 aataaaatta ttggtttaaa gggtgagtat gaatttttga atagtaatat ggaacacttg
     7861 acggttagag ctccagaaga tggtatattg catttgaaaa atagcaattt taaatctaaa
     7921 agtatttctc ttggtacaga agttgccgat gtttatccta aaattaacaa gaaaaataag
     7981 ttgataatcc aattttttgt ccctgctaac aaaatgaatg aattgaaggt aaaacaaagt
     8041 gttcgtttta aagcgaatca aactggtccg actccccttg ttgccactgg cagcattcgt
     8101 agtattcagg tagcacctac agagacggaa agtggaagtc tatatcaagt acaggctttg
     8161 attcagacgg aatcaaaaga catttctaag gtgcgctatg gtttagaagg aagggtatcg
     8221 gttatcactg gtaaaataac atggtttaat tatttaagga atttgatttt taacgattaa
     8281 gaaaaaaaag aaaatattac tattagaaaa tactttattc tataccatgg gaaatattcc
     8341 attgaaaaaa ataattcaac tgtttagtgt tgagaaatta atgacagaac ctaaattact
     8401 tagtagtaat ttaattgcga gtatcgttta aaattaattc tttaacattg acttttttga
     8461 tctgagttta agttgatggt tgatattttt atcgataaat tgatgaaaac taattattaa
     8521 aaggttttta tataagtcaa gataattttt aagttacagt tgctaagtta ttatcaatat
     8581 acatgtattt ttattgttac agttgtagtg ttagctaaca aattttgagt ataaaggaga
     8641 tttacatgga ttctaatggt tttcaaatta tggaagagta cgaattagca aaagtgaatg
     8701 ggggaatatt tccaattgtt attggtggtg tgttaattac aaagggtgct gcaattggag
     8761 caggttgctt tactgctgga attggtgctg gtttgtattt gggattgcgt taaaaaagga
     8821 gccatattat gacaattaat cttaaagatg agaatttaat caatgttact gggggaaaaa
     8881 gatattataa agtttcaggt aaaagtgtag ctatgggtgc aggtttattt acaggcggat
     8941 ttgagcttgg ctataagatt ggaaaagcaa tgcggagaaa ataatttgaa gaaaacgaga
     9001 gttgttaatc tacagtcaat cgttaatttt atttttgtca ttgatttact agctagtgtt
     9061 atttatttca taatggttgt tataggtatt cagaaattag atattttaga ggttatttta
     9121 ttactaataa caggcatctt gctatatttt tcgagaaaat aaccagtaac ttggaatatc
     9181 aatacaataa ttaatcggat gttatgaggc taaaagaaaa aggtctatca acaattgttg
     9241 atagtacctt tttacttgtt tttttgagct gtaataatgg tggttgccat ccacggccca
     9301 ccccaccaac cgttgtaacc attttttact gattgaacgg tagtgaattg attactatgt
     9361 agtaatgttt cttgatattc gcgagcatat tttaagtcaa tgatgagaag cttaccgttt
     9421 ggctttaaaa cgcgtgttgc ttctgtaagg gcgattgctc tttctgtatt cgatttaagg
     9481 ttgtgaatgg ataagctagc ggtgataatg tcaaaactat tatctgggaa ggggagtgca
     9541 agcatgtttg ccgtcataac gtttgcgact ttttcatacc ccagtcgatg aatgtttgat
     9601 gttgccgatt cactggagtt attcgattga tcgctactac gccagatatc aatcccagtt
     9661 gctttaccag gaacttttaa atatttagca acttcagtta ggacaatgcc atggcctgtc
     9721 cccaggtcta aaatttgatt atctgtttta atgtgtagtc gtcgtacagc agcctctata
     9781 attttatact ttccaaagta ggttgtatga aagtatgtaa cagctgagaa ggataaaaca
     9841 atggtagaaa tccagaaaat cagattattg gttcgaatgg cttgaaaaca gaacagtata
     9901 gctgcaaaag tcatcccaaa taatgcatat ggtgcatcga cacctttttt cattgtgctt
     9961 ctctccgttg aaagttttat ttaatatacc atacaagacg ttcaatattt tgcattgttg
    10021 aattaagtaa ataaaaaagc ctcacagtta ttagttgcga agcttcttta tttacatctt
    10081 aatatctaat tccaatggcg cgtgatcctg acgggcacca gtgtcaacga catggatgtc
    10141 ttcgacttta tcggcgatgc ggtttgagac caagtagtag tcaatccgcc agccggagtt
    10201 gttgatcttc gaagtttttg aacgctgtgc ccaccaagag tagatgtctg gttggtcagg
    10261 gtacatagca cggagagtgt ccgtgtaacc agcatccaaa agcttggtga agtgctcacg
    10321 ctcttcgtcg gtaaaaccag cggagtggtg gttttgctta ggatgcttca aatcgatttc
    10381 ttcgtgggca acgttgaagt ccccggagaa aatgactggc ttcttttcgt ttaacccatc
    10441 gatgtaattg cggtaggcat cgtcccagag ttggcgatca tctagacggg caagttcgcc
    10501 accggcgttt ggtgtgtaga cggttgaaac atagcagtct tcgaactctg ccgtgacgat
    10561 acgtccttcc tgatccattt caccgggggc accaatggct gggaagtcga ccatgattgg
    10621 ttcgtcctta gtaatgagca tcgtccccgc ataggacttg cgggctgaag atgagttggc
    10681 gtagaaatgg tagccgggga agaggccttc cagggcttcc ttttgctttt tagtcatacc
    10741 atcgacttta agttttgttt cttgaatggc aacaacgtcg ggttgcttag ccgcaatccc
    10801 ttcgagtacg ccccaggtca tgagaccacg gtcggatttg tgctcgacag ctgcgttgat
    10861 ggaatcaatg ttccaggaaa tcagtttcat ttgagtgcgc ttcctttatg cttattcttc
    10921 ttgttcttca tcaagcccgg tggccgagag gggcatgtcc gctaacttgt tcatgtaggc
    10981 ggggatggct tcggcaatct tcgatggcag cgtcacgtag gccgatttgc tgagttcagc
    11041 ggcgatggct gaatggcagt aaacggcgga tagaacggct ggaccaagtg ggtggaactg
    11101 ggcagtaaag ccagcaatca tgccggctaa cgtatcgccc atgccacccg tcgcttggta
    11161 aggaccacca accgaaagtt gataaagttc atgttctaag tatacctggg tggcatttga
    11221 tttcaaaact aagattggtt ctggatgaaa actaaccagg gcctcccagt tgttgtcctc
    11281 acgactttgg tcggcaatcg ccacttcacc taagcgttgc cattccattt gatggggggt
    11341 gagcacgact tgagccttgg ggaggtcaag gttgtgctcg gccatcatgg taatcgccga
    11401 accatcaata ataacaattt gattttcttg tacggctttg agacaggttt ttaagatgtc
    11461 aacttcctca ccgagcccgg atccaatcag cacaacgtcg gctttttgaa tataatctgc
    11521 taaatgatca tggtagtcaa ctaccatggc ctcgggtagg cgggcgtgaa tggcggtctt
    11581 attcgaaaag tccgtggcca ccgtcactag tccagcaccg gattggacag ccgcttgggc
    11641 gttcatgatg acggcgccac caaggttggc gtttcctcca atgatgagga cgcgaccgta
    11701 ggtacccttg taactctgtg acttacgtgg ctgaatcaca ttggctgcga ttttttgtga
    11761 aagttgaatc ataaaatttg tcctcctatg cacattttaa cgcggagttg tgtataatta
    11821 aaatcaaatc attagaatat tatgaaaaag cccggagcga cttttcagat gacatgagga
    11881 ggtttccatg atcaattggc aagagaaagc aaaggaagaa gaggcggctt atttagctga
    11941 cctcgctgat tatttagcaa ttccttccgt tcgtgatgat agtaaggcaa caaaggatgc
    12001 accattgggt cctggcccac gtgatgcttt ggtacatgtt ttgtccttgg ctgaacgtga
    12061 tggtttcaaa acgaagaaca tcgagaacat tgttggctac attgaaatcg gtcctgaaga
    12121 cagcgacgaa tacgttgccc tcttggccca tgccgatgtc atg
//
