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Overview
1.1
1.2
1.3
1.4
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP065921.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 701,576 | 715,319 | staphyloferrin A | Other:Non-NRP siderophore | 100%
Region 1.2 | CDPS,cyclic-lactone-autoinducer | 848,887 | 878,017 |
Region 1.3 | siderophore | 2,239,523 | 2,255,975 | staphylobactin | Other | 68%
Region 1.4 | LAP | 2,370,861 | 2,392,913 |

NZ_CP065922.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | RiPP-like | 8,043 | 15,734 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | siderophore | 701,576 | 715,319 | staphyloferrin A | Other:Non-NRP siderophore | 100%
Region 1.2 | CDPS,cyclic-lactone-autoinducer | 848,887 | 878,017 |
Region 1.3 | siderophore | 2,239,523 | 2,255,975 | staphylobactin | Other | 68%
Region 1.4 | LAP | 2,370,861 | 2,392,913 |
Region 2.1 | RiPP-like | 8,043 | 15,734 |

No secondary metabolite regions were found in these records:
  NZ_CP065923.1

Compact view
NZ_CP065921.1 - Region 1 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 701,576 - 715,319 nt. (total: 13,744 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.51 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001870.1 |  | 0.22 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000939.1 |  | 0.20 | Other | aerobactin | Grimontia hollisae
BGC0000947.1 |  | 0.19 | Other | vibrioferrin | Vibrio alginolyticus
BGC0000883.1 |  | 0.16 | Other | arginomycin | Streptomyces arginensis
BGC0000943.1 |  | 0.15 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000703.1 |  | 0.14 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000294.1 |  | 0.14 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001767.1 |  | 0.09 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000708.1 |  | 0.09 | Saccharide | lividomycin | Streptomyces lividus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.79 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001870.1 |  | 0.54 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000939.1 |  | 0.52 | Other | aerobactin | Grimontia hollisae
BGC0000947.1 |  | 0.51 | Other | vibrioferrin | Vibrio alginolyticus
BGC0000883.1 |  | 0.46 | Other | arginomycin | Streptomyces arginensis
BGC0000943.1 |  | 0.44 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000703.1 |  | 0.43 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000294.1 |  | 0.43 | NRP | acinetobactin | Acinetobacter baumannii
BGC0001767.1 |  | 0.33 | NRP | salinichelins | Salinispora pacifica CNY331
BGC0000708.1 |  | 0.33 | Saccharide | lividomycin | Streptomyces lividus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP065921.1 - Region 2 - CDPS,cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 848,887 - 878,017 nt. (total: 29,131 nt) Show pHMM detection rules used
CDPS: (CDPS or cycdipepsynth)
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | CDPS | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001291.1 |  |  | 0.40 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0000540.1 |  |  | 0.33 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001484.1 |  |  | 0.26 | Other | 2'-chloropentostatin, 2'-amino-2'-deoxyadenosine | Actinomadura sp. ATCC 39365
BGC0002009.1 |  |  | 0.26 | Polyketide | kanglemycin A, kanglemycin V1, kanglemycin V2 | Amycolatopsis vancoresmycina
BGC0001085.1 |  |  | 0.24 | NRP, Terpene | teleocidin B1 | Streptomyces blastmyceticus
BGC0000651.1 |  |  | 0.20 | Terpene | KS-505a | Streptomyces argenteolus
BGC0000158.1 |  |  | 0.18 | Polyketide | tautomycetin | Streptomyces griseochromogenes
BGC0000058.1 |  |  | 0.18 | Polyketide | FD-891 | Streptomyces graminofaciens
BGC0001872.1 |  |  | 0.18 | Polyketide | fabclavine-polyamine | Xenorhabdus bovienii SS-2004
BGC0000333.1 |  |  | 0.17 | NRP | cyclomarin D | Salinispora arenicola CNS-205

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.1 |  | 0.56 | RiPP | enterocin NKR-5-3B | Enterococcus faecium
BGC0001171.1 |  | 0.50 | RiPP | listeriolysin S | Listeria monocytogenes serotype 4b str. F2365
BGC0000540.1 |  | 0.49 | RiPP | paenibacillin | Paenibacillus polymyxa OSY-DF
BGC0001618.1 |  | 0.47 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000556.1 |  | 0.46 | RiPP | streptin | Streptococcus pyogenes
BGC0000555.1 |  | 0.46 | RiPP | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0000515.1 |  | 0.46 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0000506.1 |  | 0.46 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0000581.1 |  | 0.46 | RiPP | microcin J25 | Escherichia coli
BGC0001787.1 |  | 0.46 | RiPP | suicin 3908 | Streptococcus suis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP065921.1 - Region 3 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,239,523 - 2,255,975 nt. (total: 16,453 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000943.1 |  | 0.42 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001572.1 |  | 0.32 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001499.1 |  | 0.32 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.31 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001453.1 |  | 0.31 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000295.1 |  | 0.30 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.1 |  | 0.30 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000939.1 |  | 0.30 | Other | aerobactin | Grimontia hollisae
BGC0000942.1 |  | 0.28 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000946.1 |  | 0.25 | Other | vibrioferrin | Vibrio parahaemolyticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000943.1 |  | 0.73 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001572.1 |  | 0.65 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001499.1 |  | 0.65 | Other | aerobactin | Pantoea ananatis
BGC0001713.1 |  | 0.65 | Other | ochrobactin | Ochrobactrum anthropi
BGC0001453.1 |  | 0.64 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000295.1 |  | 0.64 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001870.1 |  | 0.63 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000939.1 |  | 0.63 | Other | aerobactin | Grimontia hollisae
BGC0000942.1 |  | 0.61 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000946.1 |  | 0.59 | Other | vibrioferrin | Vibrio parahaemolyticus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP065921.1 - Region 4 - LAP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,370,861 - 2,392,913 nt. (total: 22,053 nt) Show pHMM detection rules used
LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03882 or TIGR03604)) or TIGR03603 or TIGR03602) and not cyanobactin_synth)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | LAP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000568.1 |  | 0.21 | RiPP | microcin B17 | Escherichia coli
BGC0001521.1 |  | 0.19 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0001173.1 |  | 0.17 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000569.1 |  | 0.17 | RiPP | plantazolicin | Bacillus velezensis FZB42
BGC0001171.1 |  | 0.16 | RiPP | listeriolysin S | Listeria monocytogenes serotype 4b str. F2365
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001222.1 |  | 0.16 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.16 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000486.1 |  | 0.15 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001743.1 |  | 0.15 | RiPP | plantaricyclin | Lactobacillus plantarum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000568.1 |  | 0.54 | RiPP | microcin B17 | Escherichia coli
BGC0001521.1 |  | 0.51 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0001173.1 |  | 0.49 | RiPP | plantazolicin | Bacillus pumilus ATCC 7061
BGC0000569.1 |  | 0.48 | RiPP | plantazolicin | Bacillus velezensis FZB42
BGC0001171.1 |  | 0.47 | RiPP | listeriolysin S | Listeria monocytogenes serotype 4b str. F2365
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0001222.1 |  | 0.46 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.46 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0001743.1 |  | 0.45 | RiPP | plantaricyclin | Lactobacillus plantarum

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP065922.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 8,043 - 15,734 nt. (total: 7,692 nt) Show pHMM detection rules used
Region on contig edge.
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001222.1 |  | 0.09 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.09 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000489.1 |  | 0.07 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000626.1 |  | 0.05 | RiPP | thuricin | Bacillus thuringiensis
BGC0000607.1 |  | 0.05 | RiPP | micrococcin P1 | Macrococcus caseolyticus
BGC0000539.1 |  | 0.05 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001391.1 |  | 0.05 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  | 0.05 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000488.1 |  | 0.05 | RiPP | circularin A | Clostridium beijerinckii
BGC0001787.1 |  | 0.04 | RiPP | suicin 3908 | Streptococcus suis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001222.1 |  | 0.34 | RiPP | acidocin B | Lactobacillus acidophilus
BGC0000491.1 |  | 0.34 | RiPP | gassericin A | Lactobacillus gasseri
BGC0000489.1 |  | 0.28 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000626.1 |  | 0.24 | RiPP | thuricin | Bacillus thuringiensis
BGC0000607.1 |  | 0.23 | RiPP | micrococcin P1 | Macrococcus caseolyticus
BGC0000539.1 |  | 0.23 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0001391.1 |  | 0.22 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001311.1 |  | 0.22 | RiPP | flavecins | Ruminococcus flavefaciens FD-1
BGC0000488.1 |  | 0.22 | RiPP | circularin A | Clostridium beijerinckii
BGC0001787.1 |  | 0.20 | RiPP | suicin 3908 | Streptococcus suis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names