LOCUS       NC_017187.1            21374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_017187.1 Aliarcobacter butzleri ED-1, complete sequence.
ACCESSION   NC_017187
VERSION     NC_017187.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:04:52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 439651
            Orig. end    :: 461025
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21374
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[449651:451025](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11374
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21374
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21374
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             complement(1750..4776)
                     /gene_functions="transport (smcogs)
                     SMCOG1049:AcrB/AcrD/AcrF family protein (Score: 874;
                     E-value: 2.3e-264)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_436"
                     /transl_table=11
                     /translation="MYKIAISRPITTLMFVFALVFFGYTQIQKMPIAFLPNVDYPVVSV
                     ITTYDQGSTEIIESKITDKIEEAISGISGIDIIRSDTSKNQSIVIAQFELSKPVEEAAN
                     DVRDKVSTVDLPKEADKPIIEKFSSSSAPIITLFLSTKLDNLDKLMLHANEVVKPILQS
                     IEGVGKVEIAGFRDKIIKIYPNTTLLSKYNLDLNELALKIDEENIKKDGGRVVQEKEEL
                     NISIDSDAINVEQLENIKIKDGVRLKDVATVQETIKDERTFANYNQQKGVLLQVKKISG
                     ANEVNIANVVKEKIPYIKSLSNDFDINLLFDTTTFIESTYKSVQFDLILGCFLASLIVF
                     VFLRNFTFTIIAAISLPISILGVLAIMGWSNQTLNILTLTALTLSIGIIIDDAIVVIEN
                     IYKKLELGKSRYEAALEGVKEISFSVLAISAMLLAIFIPIANMSGIVGKFFKSFGITIV
                     ASVIISYIIAITVIPMISSLLVNPKHSKFYLMTESIFLSMDKIYKNLLIKAINFKLTTL
                     IVAFTIFVISIILSSNLGMVFMPKEDRSQFTISIKANADISMDEMKKTTMNIQEDLLSI
                     NEVDYSSLTIGLDGNIYESSIYVRLVPIDKRTKNQDEIMEEIREKSKKFRNLEINVNQT
                     DDMNSGAEIMTPFQLILKANDSKLAEESANKLIDYLKSIEGTTNIQNNIQPKKTEISIE
                     ILKQNSSKFGVKSSDIAKVIAMAYSGEIAISNFNKNGKEYDIVMRLSDDLRMNKDVINQ
                     LNVKNDKEELIALSSLININSKELASVIKRYDRQKQVTIGSDITNGLALDVLVNLVVEN
                     QEKWLLDGVTYTFEGDAKDMQDTANAFGVAIVAALIMIYLILASLYESPLQPVIIMSAM
                     PLSFTGAFLGLYLANMNMSLFSMMGLFLLLGLVGKNSTLIVDAANRNRENNTTLDEAII
                     EAGISRLRPILMTTISMCLGMLPLALSVGEGSSIKAPMAISVISGLIISTMLSLFVVPA
                     LYKLIAPLDDKIRKLYTHK"
     PFAM_domain     complement(1795..4776)
                     /aSDomain="ACR_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00873.21"
                     /description="AcrB/AcrD/AcrF family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_436_0001"
                     /evalue="2.10E-255"
                     /label="ctg1_436"
                     /locus_tag="ctg1_436"
                     /protein_end="994"
                     /protein_start="0"
                     /score="850.2"
                     /tool="antismash"
                     /translation="MYKIAISRPITTLMFVFALVFFGYTQIQKMPIAFLPNVDYPVVSV
                     ITTYDQGSTEIIESKITDKIEEAISGISGIDIIRSDTSKNQSIVIAQFELSKPVEEAAN
                     DVRDKVSTVDLPKEADKPIIEKFSSSSAPIITLFLSTKLDNLDKLMLHANEVVKPILQS
                     IEGVGKVEIAGFRDKIIKIYPNTTLLSKYNLDLNELALKIDEENIKKDGGRVVQEKEEL
                     NISIDSDAINVEQLENIKIKDGVRLKDVATVQETIKDERTFANYNQQKGVLLQVKKISG
                     ANEVNIANVVKEKIPYIKSLSNDFDINLLFDTTTFIESTYKSVQFDLILGCFLASLIVF
                     VFLRNFTFTIIAAISLPISILGVLAIMGWSNQTLNILTLTALTLSIGIIIDDAIVVIEN
                     IYKKLELGKSRYEAALEGVKEISFSVLAISAMLLAIFIPIANMSGIVGKFFKSFGITIV
                     ASVIISYIIAITVIPMISSLLVNPKHSKFYLMTESIFLSMDKIYKNLLIKAINFKLTTL
                     IVAFTIFVISIILSSNLGMVFMPKEDRSQFTISIKANADISMDEMKKTTMNIQEDLLSI
                     NEVDYSSLTIGLDGNIYESSIYVRLVPIDKRTKNQDEIMEEIREKSKKFRNLEINVNQT
                     DDMNSGAEIMTPFQLILKANDSKLAEESANKLIDYLKSIEGTTNIQNNIQPKKTEISIE
                     ILKQNSSKFGVKSSDIAKVIAMAYSGEIAISNFNKNGKEYDIVMRLSDDLRMNKDVINQ
                     LNVKNDKEELIALSSLININSKELASVIKRYDRQKQVTIGSDITNGLALDVLVNLVVEN
                     QEKWLLDGVTYTFEGDAKDMQDTANAFGVAIVAALIMIYLILASLYESPLQPVIIMSAM
                     PLSFTGAFLGLYLANMNMSLFSMMGLFLLLGLVGKNSTLIVDAANRNRENNTTLDEAII
                     EAGISRLRPILMTTISMCLGMLPLALSVGEGSSIKAPMAISVISGLIISTMLSLFVVPA
                     LYKLI"
     CDS             complement(4778..5470)
                     /locus_tag="ctg1_437"
                     /transl_table=11
                     /translation="MKKIQLIIILLTNILFADVYATYEVKALNEASLNVSTSGIVSKIN
                     TDIGNQVKKGEVLLSLNDSEEKANLEISKNEYKFLLTQYERYKKSAEVFDKNSLDKLES
                     ELKSAKDLITLNEAKLSKMKIIAPFSGVISEKNIEVGDMSNNNEKALLKLVSNEKKLLL
                     AFDSKFAQDVKAGDMFCLNSNKEDNKTCVEIYKIYPALNNEKKLNAEAYGVDLKIGNFG
                     DGLIIKGN"
     PFAM_domain     complement(5006..5383)
                     /aSDomain="HlyD_D23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16576.7"
                     /description="Barrel-sandwich domain of CusB or HlyD
                     membrane-fusion"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_437_0002"
                     /evalue="1.40E-07"
                     /label="ctg1_437"
                     /locus_tag="ctg1_437"
                     /protein_end="155"
                     /protein_start="29"
                     /score="31.0"
                     /tool="antismash"
                     /translation="EASLNVSTSGIVSKINTDIGNQVKKGEVLLSLNDSEEKANLEISK
                     NEYKFLLTQYERYKKSAEVFDKNSLDKLESELKSAKDLITLNEAKLSKMKIIAPFSGVI
                     SEKNIEVGDMSNNNEKALLKLV"
     CDS             complement(5472..6692)
                     /gene_functions="transport (smcogs) SMCOG1076:RND efflux
                     system, outer membrane lipoprotein, (Score: 77.7; E-value:
                     1.2e-23)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_438"
                     /transl_table=11
                     /translation="MFKNIFISFLISTSLYAISLKELLNSVEVTNENYQAQQALQEMSK
                     KQYESATKDNYPTFNLIGAYENNSKVLKTEPEDIAYAELKASYTLYDGERIKNNELSKK
                     SLHESQQLKTQYLKQEIMLEVIKQYFSYQNTKSAIDVINYKINELNGQIKKFEILVKND
                     LETKDKLQALIASKKEALYDIETLKIDLENSILQLSLLTGFDILPQDNDKLIEPTYDEK
                     DRFDIEAKKLEAKSVKYTSEGFNYLPTISINNSLKKQEYLHYDETYNDKFNNQIMLQIN
                     FPIFDFGKISKDKEASQLEALALNKEIAYKEKSIQIERKLALKSLESSKVKLDSAISGL
                     EATNTTYEFSKKRFDANLISYTEYLTELTKKQDANYRVILAKNDIELKKANLAFALGID
                     LLTLIKE"
     PFAM_domain     complement(5502..6008)
                     /aSDomain="OEP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02321.20"
                     /description="Outer membrane efflux protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_438_0004"
                     /evalue="2.30E-15"
                     /label="ctg1_438"
                     /locus_tag="ctg1_438"
                     /protein_end="397"
                     /protein_start="228"
                     /score="57.0"
                     /tool="antismash"
                     /translation="AKKLEAKSVKYTSEGFNYLPTISINNSLKKQEYLHYDETYNDKFN
                     NQIMLQINFPIFDFGKISKDKEASQLEALALNKEIAYKEKSIQIERKLALKSLESSKVK
                     LDSAISGLEATNTTYEFSKKRFDANLISYTEYLTELTKKQDANYRVILAKNDIELKKAN
                     LAFALG"
     PFAM_domain     complement(6084..6635)
                     /aSDomain="OEP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02321.20"
                     /description="Outer membrane efflux protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_438_0003"
                     /evalue="3.90E-16"
                     /label="ctg1_438"
                     /locus_tag="ctg1_438"
                     /protein_end="203"
                     /protein_start="19"
                     /score="59.5"
                     /tool="antismash"
                     /translation="LKELLNSVEVTNENYQAQQALQEMSKKQYESATKDNYPTFNLIGA
                     YENNSKVLKTEPEDIAYAELKASYTLYDGERIKNNELSKKSLHESQQLKTQYLKQEIML
                     EVIKQYFSYQNTKSAIDVINYKINELNGQIKKFEILVKNDLETKDKLQALIASKKEALY
                     DIETLKIDLENSILQLSLLTG"
     CDS             complement(6703..7299)
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 56.4; E-value: 8.5e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_439"
                     /transl_table=11
                     /translation="MPKIINAEEKRLEICALAYERLVEEGIVEFSLNKFIEELNMSKGQ
                     FYYYFKSKEKLIFETLKIKDIEFVEIIKENIAKKSNFLEKLVEYFALILNEEEKIFIDA
                     RKIMFESIHLYLHPKYKDEMKSCENTYINMYEIIEKIFDEEIEKGFLKEDSKKAIKVIL
                     ATIDGMYYHSLIIDDYNLKETIMDYLIETTNQLKR"
     PFAM_domain     complement(7123..7251)
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_439_0005"
                     /evalue="4.00E-07"
                     /label="ctg1_439"
                     /locus_tag="ctg1_439"
                     /protein_end="59"
                     /protein_start="16"
                     /score="29.8"
                     /tool="antismash"
                     /translation="LAYERLVEEGIVEFSLNKFIEELNMSKGQFYYYFKSKEKLIFE"
     CDS             complement(7390..8202)
                     /locus_tag="ctg1_440"
                     /transl_table=11
                     /translation="LFQFKTFKPNIKLQKWVKSYWFVDYNETLDVIEKEKIILPYDNVC
                     LLMIIDIQKNISYSDVTLKKGIYVCPPTLNRHNLNLESNIYYVDISLYPGVFYKLFGIP
                     VCELEDRVYEIKELSLNFDVSIIDLLFELKGSNLSSLNTLDEYLFKIFENMQEDSLLSN
                     LYELTKNPNLENFYNQNRLSIRQIQRKVKDFTGLAPKSIERVNRFYNTLKLIKSNENNI
                     NFKNIIFENNFYDQSSFIKEFKFFSGTTPSLFILNCENFLQYKCTIFC"
     CDS             8384..9991
                     /locus_tag="ctg1_441"
                     /transl_table=11
                     /translation="LNYKRLSKFGMKSLVLLAALPLFAVDAQKGKEVIESKCIACHTGD
                     LKDGLSRISDQRKTPEGWYMTVKRMQREHGLSITKAEETDVIKYLADYQGLTPDEIKPY
                     SYVLDKKPNVQEEGKDELLTQMCVRCHSEARIGLQRRTANEWNSLVNYHVAQFPSFEVQ
                     AQARDRDWFGVAQNEVVPYLEENFGKDKEKFEKYKKSLKNYELPKKWVMSGHTPIIGDF
                     TANLTLMKSADESYGMLIDYKYANGKEYKTTGVAIVYGKTELRASFEIDGVKYRQILHI
                     DPKTNTLEGRMFEVLHPENGSTLVGKTKDSKETTLVAVYPKAVKAGEKSTISIVGTNLV
                     GDVKLPSSLKVLKTIKHTNNEIVLDVIADKNVKTFDRNISIGTKTFKNSLVVYDKVDYI
                     KVTPDYAISRIGGEEGKDKILKEYATFEAIGYLNGKDGKKETADDIELGVLPATWSLEA
                     YDEQAQEDKDLEYVGQIDANTGKFTPSVAGPNEQRKLMTNNAGNISVVATYKDGKKELS
                     EKSHMIVTVPKFVNPPIN"
     aSDomain        8456..9985
                     /aSDomain="TIGR03908"
                     /aSTool="tigrfam"
                     /description="QH_alpha: quinohemoprotein amine
                     dehydrogenase, alpha subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_441_0001"
                     /evalue="3.40E-171"
                     /identifier="TIGR03908"
                     /label="ctg1_441"
                     /locus_tag="ctg1_441"
                     /protein_end="534"
                     /protein_start="24"
                     /score="568.2"
                     /tool="antismash"
                     /translation="VDAQKGKEVIESKCIACHTGDLKDGLSRISDQRKTPEGWYMTVKR
                     MQREHGLSITKAEETDVIKYLADYQGLTPDEIKPYSYVLDKKPNVQEEGKDELLTQMCV
                     RCHSEARIGLQRRTANEWNSLVNYHVAQFPSFEVQAQARDRDWFGVAQNEVVPYLEENF
                     GKDKEKFEKYKKSLKNYELPKKWVMSGHTPIIGDFTANLTLMKSADESYGMLIDYKYAN
                     GKEYKTTGVAIVYGKTELRASFEIDGVKYRQILHIDPKTNTLEGRMFEVLHPENGSTLV
                     GKTKDSKETTLVAVYPKAVKAGEKSTISIVGTNLVGDVKLPSSLKVLKTIKHTNNEIVL
                     DVIADKNVKTFDRNISIGTKTFKNSLVVYDKVDYIKVTPDYAISRIGGEEGKDKILKEY
                     ATFEAIGYLNGKDGKKETADDIELGVLPATWSLEAYDEQAQEDKDLEYVGQIDANTGKF
                     TPSVAGPNEQRKLMTNNAGNISVVATYKDGKKELSEKSHMIVTVPKFVNPPI"
     PFAM_domain     8465..8965
                     /aSDomain="Dehyd-heme_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09098.12"
                     /description="Quinohemoprotein amine dehydrogenase A, alpha
                     subunit, haem binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_441_0006"
                     /evalue="6.50E-90"
                     /label="ctg1_441"
                     /locus_tag="ctg1_441"
                     /protein_end="194"
                     /protein_start="27"
                     /score="299.2"
                     /tool="antismash"
                     /translation="QKGKEVIESKCIACHTGDLKDGLSRISDQRKTPEGWYMTVKRMQR
                     EHGLSITKAEETDVIKYLADYQGLTPDEIKPYSYVLDKKPNVQEEGKDELLTQMCVRCH
                     SEARIGLQRRTANEWNSLVNYHVAQFPSFEVQAQARDRDWFGVAQNEVVPYLEENFGKD
                     KEKF"
     PFAM_domain     8993..9304
                     /aSDomain="Qn_am_d_aII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14930.8"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain II"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_441_0007"
                     /evalue="3.80E-35"
                     /label="ctg1_441"
                     /locus_tag="ctg1_441"
                     /protein_end="307"
                     /protein_start="203"
                     /score="120.4"
                     /tool="antismash"
                     /translation="YELPKKWVMSGHTPIIGDFTANLTLMKSADESYGMLIDYKYANGK
                     EYKTTGVAIVYGKTELRASFEIDGVKYRQILHIDPKTNTLEGRMFEVLHPENGSTLVGK
                     "
     PFAM_domain     9320..9565
                     /aSDomain="Qn_am_d_aIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09099.12"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain III"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_441_0008"
                     /evalue="4.20E-32"
                     /label="ctg1_441"
                     /locus_tag="ctg1_441"
                     /protein_end="394"
                     /protein_start="312"
                     /score="110.4"
                     /tool="antismash"
                     /translation="ETTLVAVYPKAVKAGEKSTISIVGTNLVGDVKLPSSLKVLKTIKH
                     TNNEIVLDVIADKNVKTFDRNISIGTKTFKNSLVVYD"
     PFAM_domain     9578..9985
                     /aSDomain="Qn_am_d_aIV"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09100.12"
                     /description="Quinohemoprotein amine dehydrogenase, alpha
                     subunit domain IV"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_441_0009"
                     /evalue="3.80E-56"
                     /label="ctg1_441"
                     /locus_tag="ctg1_441"
                     /protein_end="534"
                     /protein_start="398"
                     /score="188.6"
                     /tool="antismash"
                     /translation="IKVTPDYAISRIGGEEGKDKILKEYATFEAIGYLNGKDGKKETAD
                     DIELGVLPATWSLEAYDEQAQEDKDLEYVGQIDANTGKFTPSVAGPNEQRKLMTNNAGN
                     ISVVATYKDGKKELSEKSHMIVTVPKFVNPPI"
     CDS             10001..11374
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Quinohemoprotein_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_442"
                     /sec_met_domain="PF04055 (E-value: 6.3e-15, bitscore: 53.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6e-13, bitscore: 46.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.4e-15, bitscore:
                     51.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="Quinohemoprotein_rSAM_RRE (E-value:
                     1.3e-11, bitscore: 41.4, seeds: 15, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MSINNYNLIKTNYHILEIDSKEFLFHIPTSSVFELSTESANLLRK
                     MENKEEITKDEEEIVEEFKELNIIGSRFFVKEEDTKIEHFPAKALVLNVTSGCNLSCTY
                     CYKADLTSLKNSGQMTFEIAKDAIDMFYKESPYLKEYSITFFGGEPLSNLPLIKQIIAY
                     ANDFFESKGLKIGYSMTSNATLLTDEVIRYLHESKVDLTISIDGPESLHNKTRVYENGK
                     GSYEKVAKNVAKLLDIYKNRTVGARVTLTRGVTDVKTIWNHLRYDLKFKEVGFAPATSG
                     DNDFFNLSDSDLKKVFVGFKELGEDYINEAIKGNFNGFSNLHRTVIDIHEGRKKKLPCG
                     AGVGLLSVSYKGDIDLCHRFTGSDYPSFGNIEKGLDKKALGSFLEKRANEKDTSCQTCR
                     IRNLCAGGCYHESYIKYGTPEKSVLHYCDDMRNWIDFAVEAYIRIKAKNPEFFTKYFK"
     aSDomain        10034..11365
                     /aSDomain="TIGR03906"
                     /aSTool="tigrfam"
                     /description="quino_hemo_SAM: quinohemoprotein amine
                     dehydrogenase maturation protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_442_0002"
                     /evalue="9.30E-173"
                     /identifier="TIGR03906"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="455"
                     /protein_start="11"
                     /score="573.1"
                     /tool="antismash"
                     /translation="NYHILEIDSKEFLFHIPTSSVFELSTESANLLRKMENKEEITKDE
                     EEIVEEFKELNIIGSRFFVKEEDTKIEHFPAKALVLNVTSGCNLSCTYCYKADLTSLKN
                     SGQMTFEIAKDAIDMFYKESPYLKEYSITFFGGEPLSNLPLIKQIIAYANDFFESKGLK
                     IGYSMTSNATLLTDEVIRYLHESKVDLTISIDGPESLHNKTRVYENGKGSYEKVAKNVA
                     KLLDIYKNRTVGARVTLTRGVTDVKTIWNHLRYDLKFKEVGFAPATSGDNDFFNLSDSD
                     LKKVFVGFKELGEDYINEAIKGNFNGFSNLHRTVIDIHEGRKKKLPCGAGVGLLSVSYK
                     GDIDLCHRFTGSDYPSFGNIEKGLDKKALGSFLEKRANEKDTSCQTCRIRNLCAGGCYH
                     ESYIKYGTPEKSVLHYCDDMRNWIDFAVEAYIRIKAKNPEFFTKY"
     PFAM_domain     10283..10672
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_442_0010"
                     /evalue="9.60E-11"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="224"
                     /protein_start="94"
                     /score="42.4"
                     /tool="antismash"
                     /translation="TSGCNLSCTYCYKADLTSLKNSGQMTFEIAKDAIDMFYKESPYLK
                     EYSITFFGGEPLSNLPLIKQIIAYANDFFESKGLKIGYSMTSNATLLTDEVIRYLHESK
                     VDLTISIDGPESLHNKTRVYENGKGS"
     aSDomain        11015..11281
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_442_0003"
                     /evalue="2.00E-14"
                     /identifier="TIGR04085"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="427"
                     /protein_start="338"
                     /score="51.8"
                     /tool="antismash"
                     /translation="CGAGVGLLSVSYKGDIDLCHRFTGSDYPSFGNIEKGLDKKALGSF
                     LEKRANEKDTSCQTCRIRNLCAGGCYHESYIKYGTPEKSVLHYC"
     CDS             11385..11705
                     /locus_tag="ctg1_443"
                     /transl_table=11
                     /translation="MKHLKPITPKAKLLEEALKEGNANEVVAMSSVVGCVTTFDPGWEV
                     DSDGGVASLCQPMEADLYGCSDPCWWPTQVPDTSSSYKKWSEKAPATKDDWRELENVYP
                     KM"
     PFAM_domain     11475..11699
                     /aSDomain="QH-AmDH_gamma"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08992.13"
                     /description="Quinohemoprotein amine dehydrogenase, gamma
                     subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_443_0011"
                     /evalue="1.00E-42"
                     /label="ctg1_443"
                     /locus_tag="ctg1_443"
                     /protein_end="105"
                     /protein_start="30"
                     /score="144.1"
                     /tool="antismash"
                     /translation="SVVGCVTTFDPGWEVDSDGGVASLCQPMEADLYGCSDPCWWPTQV
                     PDTSSSYKKWSEKAPATKDDWRELENVYPK"
     CDS             11723..12856
                     /locus_tag="ctg1_444"
                     /transl_table=11
                     /translation="MLNKKFIKSGLGLLSFSLILSSSLSTNLNAANVKLKSNHDYLVTV
                     TRPNNIALVDLEKNEMINECKIDEAFSPGAIVLSPNNKVAFVLGEYGEEVAGYEIETCK
                     KVFHTSLTQGNIRAKSLFGLSVNEDGTKVYAIYNRTEMLNDRYKVLPPYFSVYNVADGL
                     DAKPVKSFEMPRQTTVVSTGKDGTVYVVGSDLYKVNPKSGDIEVAKKIVKWGKEGYSDL
                     DSAANYIIGQQTGDLTALYATVKYDDPKNPSEEEGTTYWGITSVDLNTGEIIQQEISEY
                     ETLMFTAIRSPKDQNILYGVLNDLTKFDIKEQKVLKRVVTDHTYYSVVPSVDGEKLYLG
                     GCLNDIAIYDANSLEKLGNIKLSGDMGSAALQVFKTK"
     aSDomain        11837..12847
                     /aSDomain="TIGR03907"
                     /aSTool="tigrfam"
                     /description="QH_beta: quinohemoprotein amine
                     dehydrogenase, beta subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_444_0004"
                     /evalue="2.60E-105"
                     /identifier="TIGR03907"
                     /label="ctg1_444"
                     /locus_tag="ctg1_444"
                     /protein_end="375"
                     /protein_start="38"
                     /score="350.2"
                     /tool="antismash"
                     /translation="HDYLVTVTRPNNIALVDLEKNEMINECKIDEAFSPGAIVLSPNNK
                     VAFVLGEYGEEVAGYEIETCKKVFHTSLTQGNIRAKSLFGLSVNEDGTKVYAIYNRTEM
                     LNDRYKVLPPYFSVYNVADGLDAKPVKSFEMPRQTTVVSTGKDGTVYVVGSDLYKVNPK
                     SGDIEVAKKIVKWGKEGYSDLDSAANYIIGQQTGDLTALYATVKYDDPKNPSEEEGTTY
                     WGITSVDLNTGEIIQQEISEYETLMFTAIRSPKDQNILYGVLNDLTKFDIKEQKVLKRV
                     VTDHTYYSVVPSVDGEKLYLGGCLNDIAIYDANSLEKLGNIKLSGDMGSAALQVFK"
     CDS             12871..14508
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 241.5; E-value: 3e-73)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_445"
                     /transl_table=11
                     /translation="MFKNIIYPLLKKNKRGFFVIFFFSILVSLGGAVQPYIMQHIIDNA
                     ILASNINQLIFLVSISFFLTVFVMIISYINEIYYTKNSMNILFEFRKIVFNKLFLHDKT
                     FLNNYHSADLMSRVQGDISELQRFYTDSVFSLFSTIISLVFICFIVYSYNIKLMILILI
                     FLPIEFFCLKPLYPHIQNSTKTMRESTSNIGKFFIENFRYMLTIKNLGAKEQTLEKLDF
                     IQDDYKNVVIKNKKINLLFSQIPAFISLLGKTIIVSYGGYLTIKGELKIGELFAFLTYF
                     TMILAPVHTILGVINNFPKVKVSLNRVLEILPKEKDNIELKTTNFDLNIKNLEFSYSNN
                     KIFENLNLFIKERSKIAIIGKNGAGKTTFADLLCGFLKANNGDIFIGNEKIGENNYINF
                     SSYLVKLEQTPIIFDDTLKNNLLLAKNSASEEELIDCLKKTGMCKWFRNLQKGLNTNLL
                     ESGANLSGGQKQRLALSRLILLNPKIIILDEFTSSIDEKDTSWFYENISTIFPNSTIIA
                     ITHNLNMLSHFDKVYLLENKTLKEYKNV"
     PFAM_domain     12922..13734
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_445_0012"
                     /evalue="3.00E-37"
                     /label="ctg1_445"
                     /locus_tag="ctg1_445"
                     /protein_end="288"
                     /protein_start="17"
                     /score="128.9"
                     /tool="antismash"
                     /translation="FVIFFFSILVSLGGAVQPYIMQHIIDNAILASNINQLIFLVSISF
                     FLTVFVMIISYINEIYYTKNSMNILFEFRKIVFNKLFLHDKTFLNNYHSADLMSRVQGD
                     ISELQRFYTDSVFSLFSTIISLVFICFIVYSYNIKLMILILIFLPIEFFCLKPLYPHIQ
                     NSTKTMRESTSNIGKFFIENFRYMLTIKNLGAKEQTLEKLDFIQDDYKNVVIKNKKINL
                     LFSQIPAFISLLGKTIIVSYGGYLTIKGELKIGELFAFLTYFTMILAPV"
     PFAM_domain     13900..14343
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_445_0013"
                     /evalue="1.80E-25"
                     /label="ctg1_445"
                     /locus_tag="ctg1_445"
                     /protein_end="491"
                     /protein_start="343"
                     /score="90.1"
                     /tool="antismash"
                     /translation="ENLNLFIKERSKIAIIGKNGAGKTTFADLLCGFLKANNGDIFIGN
                     EKIGENNYINFSSYLVKLEQTPIIFDDTLKNNLLLAKNSASEEELIDCLKKTGMCKWFR
                     NLQKGLNTNLLESGANLSGGQKQRLALSRLILLNPKIIILDEFT"
     CDS             14501..15130
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_446"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.7e-06, bitscore:
                     23.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKEVFVALIDSGCNFETYEKIAIHIENNRIKIKNQNNINFEHGN
                     VIGNIIKDENINIYDIQVFNENLSTTPHHIFGALNYLKDKKVDVISMSLGLKTNYKEIE
                     ELCREFIKKGVVIISSYPKSGQEFVYPASYENVIKVTSEGKCMDDKVVVLDKEKLFFGA
                     NPFSTVKNVAGSSVAVAKFTKEFCSYIKKGFSKIEIIEEFSKRIIK"
     PFAM_domain     14639..14926
                     /aSDomain="Peptidase_S8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00082.24"
                     /description="Subtilase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_446_0014"
                     /evalue="4.30E-06"
                     /label="ctg1_446"
                     /locus_tag="ctg1_446"
                     /protein_end="142"
                     /protein_start="46"
                     /score="26.2"
                     /tool="antismash"
                     /translation="IGNIIKDENINIYDIQVFNENLSTTPHHIFGALNYLKDKKVDVIS
                     MSLGLKTNYKEIEELCREFIKKGVVIISSYPKSGQEFVYPASYENVIKVTS"
     CDS             15127..16452
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 80.5; E-value: 2.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_447"
                     /sec_met_domain="Trp_halogenase (E-value: 7.4e-16,
                     bitscore: 55.0, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNSNKKIVVLGAGIAGSSTAIGLKKLGFDVTVIYKKRPFTAYEGF
                     SQKTKEGLISLGCIKASKLLVEQSLRNSNWASKTHKVNYEFVVNRNIFDKTLLEDLKEY
                     QIKIIEAKVIGSIDYLDEKPKIVYKIDEKKYDLIADFVIDARGRFTPFKDEYICGPKSF
                     SLLQELELEDINENQTSIDSVKDGWIWQAYVGDKRGYIQFSCDEELANKVNCFEDMLKI
                     LQEQNIELWSLNNYKVVGKLVKRDSFCKIHKKIINNKMMLVGDSASSIDPLSGNGAFQA
                     MSMSSITPFVINTILNKSEIEQKVAIDFYKSRVEFIFDKFTKVGKEFYILEKRFNTPFW
                     QNRQTWPQDKNELEKKVPRIEKKAVVKDGFVNESEVVITKHNPFGACYFGNIEIIDLAK
                     YCLENSFEKSLDYFDIFCKERNVPLQVGNSLKNWCIKEEILG"
     PFAM_domain     15298..16227
                     /aSDomain="Trp_halogenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04820.16"
                     /description="Tryptophan halogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_447_0015"
                     /evalue="6.50E-15"
                     /label="ctg1_447"
                     /locus_tag="ctg1_447"
                     /protein_end="367"
                     /protein_start="57"
                     /score="55.0"
                     /tool="antismash"
                     /translation="CIKASKLLVEQSLRNSNWASKTHKVNYEFVVNRNIFDKTLLEDLK
                     EYQIKIIEAKVIGSIDYLDEKPKIVYKIDEKKYDLIADFVIDARGRFTPFKDEYICGPK
                     SFSLLQELELEDINENQTSIDSVKDGWIWQAYVGDKRGYIQFSCDEELANKVNCFEDML
                     KILQEQNIELWSLNNYKVVGKLVKRDSFCKIHKKIINNKMMLVGDSASSIDPLSGNGAF
                     QAMSMSSITPFVINTILNKSEIEQKVAIDFYKSRVEFIFDKFTKVGKEFYILEKRFNTP
                     FWQNRQTWPQDKNELEKKVPRIEKKAVVK"
     CDS             complement(16461..18320)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 146.9; E-value:
                     1.9e-44)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_448"
                     /transl_table=11
                     /translation="MSSNKKITLIIFTMISILAVIIIILVALGSRHSGYDGAKKRAYLT
                     AQLVKNSLTSHMINGTMHQRDTFLSSLNNLQGIKELWVVRSKSVSEQFGNSLLATEKAR
                     DNIDLDVLKNGKEKVIVNESLKDATLRITIPYTASSLDKPNCMSCHNAQEGQVLGAISL
                     TFDIQEDRISNIVILINVVATISVFLILILIYLRKKITPFTNSFDSITETLKQVHEGDY
                     SVRVKEGVLKEDKEASIWLNELIEKLETVLTGIEKNLTSFVHNRATIFSNDKLLTAKEI
                     IEDITEIYNYKKTIETDLTKEDIFYRLIQVLKNKLNIESFYIFETDLIKDERRTIYPVK
                     EVEKPCCSISKGIKAGCRAERTNTIVSSENFPEICRIANCSGETNHICIPFLINEQKNI
                     VIHIVCKDKDSLQNTKYQIGIIKKYLEETKPILESKLLMDALREKNLVDGLTGLYNRRY
                     LDEFIEKKLPHETQNGSKFAIMFLDIDYFKMINDTYGHDAGDAILQKLSDTMKASISEN
                     EFIVRFGGEEFLIIMKNPTETSARELATKINQEFAKLVFNYNGQAFSKTVSIGYSFFPD
                     DADQIWKCIKYADISLYEAKETGRNKIVRFQKEFLKSADKKSY"
     aSDomain        complement(16509..16991)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_448_0005"
                     /evalue="1.50E-45"
                     /identifier="TIGR00254"
                     /label="ctg1_448"
                     /locus_tag="ctg1_448"
                     /protein_end="604"
                     /protein_start="443"
                     /score="152.9"
                     /tool="antismash"
                     /translation="KNLVDGLTGLYNRRYLDEFIEKKLPHETQNGSKFAIMFLDIDYFK
                     MINDTYGHDAGDAILQKLSDTMKASISENEFIVRFGGEEFLIIMKNPTETSARELATKI
                     NQEFAKLVFNYNGQAFSKTVSIGYSFFPDDADQIWKCIKYADISLYEAKETGRNKIV"
     PFAM_domain     complement(16515..16982)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_448_0016"
                     /evalue="1.50E-45"
                     /label="ctg1_448"
                     /locus_tag="ctg1_448"
                     /protein_end="602"
                     /protein_start="446"
                     /score="155.0"
                     /tool="antismash"
                     /translation="VDGLTGLYNRRYLDEFIEKKLPHETQNGSKFAIMFLDIDYFKMIN
                     DTYGHDAGDAILQKLSDTMKASISENEFIVRFGGEEFLIIMKNPTETSARELATKINQE
                     FAKLVFNYNGQAFSKTVSIGYSFFPDDADQIWKCIKYADISLYEAKETGRNK"
     CDS             complement(18391..19098)
                     /locus_tag="ctg1_449"
                     /transl_table=11
                     /translation="MDILPAIDLKDGKAVRLSKGLMDSAKIYSDEPWQVAKRFEELGSK
                     WVHIVDLNGAFAGKPANLEQIKKIRENCNLKIELGGGIRDEETIKMYLELGVDRLILGS
                     IAVKDPIFVKKMASKYPIAVGIDAMNGMVAVEGWAEVSTMKATDLAKEFANAGVQAIIC
                     TDISKDGMLCGVNVEFTESIALASSVDTIASGGVKDIQDIINCKANGNISGVIVGKAFY
                     EGTLDLEEAFKIL"
     aSDomain        complement(18406..19092)
                     /aSDomain="TIGR00007"
                     /aSTool="tigrfam"
                     /description="TIGR00007:
                     1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylidenea
                     mino]imidazole-4-carboxamide isomera"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_449_0006"
                     /evalue="3.10E-81"
                     /identifier="TIGR00007"
                     /label="ctg1_449"
                     /locus_tag="ctg1_449"
                     /protein_end="231"
                     /protein_start="2"
                     /score="270.3"
                     /tool="antismash"
                     /translation="ILPAIDLKDGKAVRLSKGLMDSAKIYSDEPWQVAKRFEELGSKWV
                     HIVDLNGAFAGKPANLEQIKKIRENCNLKIELGGGIRDEETIKMYLELGVDRLILGSIA
                     VKDPIFVKKMASKYPIAVGIDAMNGMVAVEGWAEVSTMKATDLAKEFANAGVQAIICTD
                     ISKDGMLCGVNVEFTESIALASSVDTIASGGVKDIQDIINCKANGNISGVIVGKAFYEG
                     TLDLEEA"
     PFAM_domain     complement(18421..19092)
                     /aSDomain="His_biosynth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00977.23"
                     /description="Histidine biosynthesis protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_449_0017"
                     /evalue="3.00E-75"
                     /label="ctg1_449"
                     /locus_tag="ctg1_449"
                     /protein_end="226"
                     /protein_start="2"
                     /score="252.7"
                     /tool="antismash"
                     /translation="ILPAIDLKDGKAVRLSKGLMDSAKIYSDEPWQVAKRFEELGSKWV
                     HIVDLNGAFAGKPANLEQIKKIRENCNLKIELGGGIRDEETIKMYLELGVDRLILGSIA
                     VKDPIFVKKMASKYPIAVGIDAMNGMVAVEGWAEVSTMKATDLAKEFANAGVQAIICTD
                     ISKDGMLCGVNVEFTESIALASSVDTIASGGVKDIQDIINCKANGNISGVIVGKAFYEG
                     TL"
     CDS             complement(19110..19961)
                     /locus_tag="ctg1_450"
                     /transl_table=11
                     /translation="MKTIAISGANGFVGTSLTNFFSSFGYKIVPLSRDILNNKSKLEEV
                     LNSTDIVINLAGANIINRWSESYKKLLYSSRIDTTSKIVNAISSISNKPKLLISTSAVG
                     IYDNKSIYDENGSFSNDFLSNLCQDWEKEALKVKNGTTKVAIFRFGIILGKDGGALQKM
                     ITPFKFGLGGTIGSGKQAFSFIHINDLLNAYKFVIENDYDGVFNLTAPTPTTNKGLTLA
                     LGKTLKRPTILPVPEFVLKLIFSEGARVLTDGQSAIPKKLLNLGFEFKFKTIEETIENL
                     CS"
     PFAM_domain     complement(19119..19259)
                     /aSDomain="DUF1731"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08338.13"
                     /description="Domain of unknown function (DUF1731)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_450_0019"
                     /evalue="1.30E-15"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="281"
                     /protein_start="234"
                     /score="57.0"
                     /tool="antismash"
                     /translation="VPEFVLKLIFSEGARVLTDGQSAIPKKLLNLGFEFKFKTIEETIE
                     NL"
     aSDomain        complement(19131..19952)
                     /aSDomain="TIGR01777"
                     /aSTool="tigrfam"
                     /description="yfcH: TIGR01777 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_450_0007"
                     /evalue="7.80E-90"
                     /identifier="TIGR01777"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="277"
                     /protein_start="3"
                     /score="299.3"
                     /tool="antismash"
                     /translation="IAISGANGFVGTSLTNFFSSFGYKIVPLSRDILNNKSKLEEVLNS
                     TDIVINLAGANIINRWSESYKKLLYSSRIDTTSKIVNAISSISNKPKLLISTSAVGIYD
                     NKSIYDENGSFSNDFLSNLCQDWEKEALKVKNGTTKVAIFRFGIILGKDGGALQKMITP
                     FKFGLGGTIGSGKQAFSFIHINDLLNAYKFVIENDYDGVFNLTAPTPTTNKGLTLALGK
                     TLKRPTILPVPEFVLKLIFSEGARVLTDGQSAIPKKLLNLGFEFKFKTIEET"
     PFAM_domain     complement(19344..19952)
                     /aSDomain="Epimerase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01370.23"
                     /description="NAD dependent epimerase/dehydratase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_450_0018"
                     /evalue="9.90E-11"
                     /label="ctg1_450"
                     /locus_tag="ctg1_450"
                     /protein_end="206"
                     /protein_start="3"
                     /score="41.6"
                     /tool="antismash"
                     /translation="IAISGANGFVGTSLTNFFSSFGYKIVPLSRDILNNKSKLEEVLNS
                     TDIVINLAGANIINRWSESYKKLLYSSRIDTTSKIVNAISSISNKPKLLISTSAVGIYD
                     NKSIYDENGSFSNDFLSNLCQDWEKEALKVKNGTTKVAIFRFGIILGKDGGALQKMITP
                     FKFGLGGTIGSGKQAFSFIHINDLLNAYKFVIENDYDGVF"
     CDS             complement(19982..20590)
                     /locus_tag="ctg1_451"
                     /transl_table=11
                     /translation="VIGIIDYNMGNLASVYNACHLLDAKATIVKKPEDLKNFNRVILPG
                     VGAYKDAMEHLIKTGMNEAILEFAKSGKPMIGICLGMQLLFESSQEFGHTDGLGLIDGV
                     VVKFDKSKMNEDFKIPHMGWNTIVNKEHPLFEGLHNPYLYFVHSYHAVTNEKNIIGKTT
                     YGYEFASAVNKDNIYGFQPHPEKSHDNGLKILKNFMNLN"
     aSDomain        complement(19991..20587)
                     /aSDomain="TIGR01855"
                     /aSTool="tigrfam"
                     /description="IMP_synth_hisH: imidazole glycerol phosphate
                     synthase, glutamine amidotransferase subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_451_0008"
                     /evalue="2.60E-67"
                     /identifier="TIGR01855"
                     /label="ctg1_451"
                     /locus_tag="ctg1_451"
                     /protein_end="200"
                     /protein_start="1"
                     /score="224.4"
                     /tool="antismash"
                     /translation="IGIIDYNMGNLASVYNACHLLDAKATIVKKPEDLKNFNRVILPGV
                     GAYKDAMEHLIKTGMNEAILEFAKSGKPMIGICLGMQLLFESSQEFGHTDGLGLIDGVV
                     VKFDKSKMNEDFKIPHMGWNTIVNKEHPLFEGLHNPYLYFVHSYHAVTNEKNIIGKTTY
                     GYEFASAVNKDNIYGFQPHPEKSHDNGLKILKNFMN"
     PFAM_domain     complement(19997..20578)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_451_0020"
                     /evalue="2.70E-20"
                     /label="ctg1_451"
                     /locus_tag="ctg1_451"
                     /protein_end="198"
                     /protein_start="4"
                     /score="73.0"
                     /tool="antismash"
                     /translation="IDYNMGNLASVYNACHLLDAKATIVKKPEDLKNFNRVILPGVGAY
                     KDAMEHLIKTGMNEAILEFAKSGKPMIGICLGMQLLFESSQEFGHTDGLGLIDGVVVKF
                     DKSKMNEDFKIPHMGWNTIVNKEHPLFEGLHNPYLYFVHSYHAVTNEKNIIGKTTYGYE
                     FASAVNKDNIYGFQPHPEKSHDNGLKILKNF"
     CDS             complement(20633..21205)
                     /locus_tag="ctg1_452"
                     /transl_table=11
                     /translation="MKCISCDKLSFSIICKTCQITLLEPSFHKREIEDGFFNYSFYSLS
                     ELEDLINSKYYFYGDRVFNILAKLSFAKFALNFDFPSEVLAIPIDDHTRHDFSHCAILA
                     KHLKSKIIKPKYNSLKATNIVKYAGKNLEFRQKNSRKFQINNLSDKFVILCDDLITTGT
                     TIIQAKKALEKKNNQILFSLTLADAKL"
     PFAM_domain     complement(20645..20896)
                     /aSDomain="Pribosyltran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00156.29"
                     /description="Phosphoribosyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_452_0021"
                     /evalue="1.30E-06"
                     /label="ctg1_452"
                     /locus_tag="ctg1_452"
                     /protein_end="187"
                     /protein_start="103"
                     /score="28.0"
                     /tool="antismash"
                     /translation="AKHLKSKIIKPKYNSLKATNIVKYAGKNLEFRQKNSRKFQINNLS
                     DKFVILCDDLITTGTTIIQAKKALEKKNNQILFSLTLAD"
ORIGIN
        1 agaattataa atttataact ccaccttgta gtagcgctga tttaacttta tttattcaat
       61 caattgattc aacttttgat ttaaatgtta gtggtaaatt tatgctaaaa gatgttgata
      121 gcaacatgat aagttttgga ataaatactc aaattgatga attaaacgct caaaatgaga
      181 ttttatattc taaattagaa ttgttaagaa cacatatttt atcatttatg aaaagtgatg
      241 attcaaattt tgtaagtata aatagacttg ataaagaggg attttttatc actttgacaa
      301 aaaatagatt taacttagtt aaaaaagagt tattaaattc tcatttaata gttgatgatg
      361 aattatattt atttaaagat tttaatataa aagttcaaac aaattcagta aagatttttt
      421 gtaaattaac tgaagatatt tcagataaat atgttcataa tttacgaaaa attgtagagt
      481 taaataagct tgtttttaaa gaaaaaattc acgaatttga aaagaaattt gctactttac
      541 ttcaagaatt agtacagttt atagctgagg ttgatttaac agtttcaaat ataaaaacag
      601 caaaaaaata caactatact tgtccaaaga ttgtaaaaac aaaagagaat gaaaactttt
      661 tagaacttat tgatttaaga catccaataa ttgaagcaaa tgaagaacaa ggaatttatg
      721 taccaaatga tattattttg ggagaactaa gtcttgcttc tgaagaatac aaagataata
      781 taattataaa aaattcaaat ccagtaaata tgtacaataa taaaatgcat ggagttttac
      841 tttatggaat aaactcttct ggaaaatctt ctttgatgaa atcgattgga attgcagttg
      901 ttttagcaca agctggattt tatgtaccat gtcgttctat gagattttca atttttgatg
      961 ctgtttatac aagaatcagt ggagctgata atattgcaaa aggattatca tcttttgcag
     1021 ttgagatgtt ggagttaaaa aatatcttta atagagctac taaaaattca cttattttgg
     1081 gtgatgaaat ctctcatagc acagaaacta tgagtggatt aagtattgtt gcaagtgcta
     1141 ttttaaaact ttcaaaactt gaagctttat ttgtttttgc tacacattta catcaacttc
     1201 ctgagattga agagatacaa aaactaaaaa atatcatctc tttacattta tcagtttttt
     1261 ataaagatga tgaagataaa cttatttttg atagaaaatt agcttatgga agtggttctt
     1321 ctatgtatgg attagagtat gcaaaatcac ttcatatgga taaagagttt ttaaatattg
     1381 caaatgaaat aagaaaaaaa ttaactgacg attataatcc tttagaaaga ctatctcaaa
     1441 agaaaacttc aaaatataac aatagtgttt ttgcttcaaa ctgtgtaatt tgtgggcgag
     1501 cttgtgatga tgttcaccat ataaaagaac aagcacgagc aaataaagat ggctttatag
     1561 gtcatattaa tgcaaaccat aaatacaatc taattccact ttgtaaagag caccataaaa
     1621 tggtacatga tggaactatt aatataaatg gttttgttgc aacttctaaa ggtttagaat
     1681 tacattatac aatggttgag caaaagtaaa tctttttaaa tattccccaa gcaaatgctc
     1741 gggaaatatc tatttgtgag tataaagttt tctgatttta tcatcaagtg gagctattaa
     1801 tttatataaa gctggaacta caaataaact taacattgta gatattatta aaccacttat
     1861 aacactaata gccataggag ctttgatact tgaaccttca ccaacagaaa gtgcaagggg
     1921 aagcatacct aaacacatag aaatagttgt catcaaaatt ggtcttagtc ttgatatccc
     1981 tgcttcaata atcgcttcat ctaaagttgt attattttct ctatttctat ttgcagcatc
     2041 aactattaaa gttgagtttt taccaactaa acctagaagt aaaaataatc ccatcatact
     2101 aaataaactc atattcatat ttgctaaata aagccctaaa aaagctcctg taaaactaag
     2161 tggcattgca ctcatgatga taactggctg aagaggtgat tcatataatg aagcaagaat
     2221 taaatatatc attataagag cagctactat tgcaacgcca aaagcatttg ctgtatcttg
     2281 catatctttt gcatctcctt caaaagtata agttactcca tctaaaagcc atttctcttg
     2341 attttcaact acaaggttta ctaaaacatc aagcgctaaa ccatttgtta tatcacttcc
     2401 aattgtaact tgtttttgtc tatcatatct ttttatcaca gaagctaatt ctttactatt
     2461 tatattaatc aaacttgata atgcaataag ttcttcttta tcatttttta catttaattg
     2521 atttataaca tctttgttca ttcttaaatc atctgatagt ctcattacaa tatcatactc
     2581 tttaccattt ttattaaaat tacttattgc aatttctcct gaatatgcca ttgcaattac
     2641 ttttgcaata tcactacttt ttactccaaa ttttgaagag ttttgtttta atatttcaat
     2701 tgagatttct gtttttttag gctgaatatt attttgaata tttgttgttc cttctataga
     2761 ttttaaataa tcaatcaatt tattagccga ttcctcagcg agttttgaat catttgcttt
     2821 taagataagt tgaaaaggag tcatgatttc agcacctgag ttcatatcat cagtttggtt
     2881 tacatttatt tcaagatttc taaatttttt tgatttttct ctaatttctt ccataatttc
     2941 atcttgattt ttagttcttt tatctattgg aactaatctt acatagattg aactttcata
     3001 aatatttcca tctaatccaa tagtcaaaga agagtaatca acttcattta ttgaaagtaa
     3061 atcttcttgg atattcattg tggttttttt catctcatcc atagaaatat cagcatttgc
     3121 tttaatagaa attgtaaatt gacttctatc ttctttgggc ataaaaacca ttcctagatt
     3181 tgaagagagt attattgaaa taacaaatat tgtaaatgca acaattaaag ttgtaagttt
     3241 aaagtttatt gcttttatta aaagattttt atatatttta tccattgata aaaatatcga
     3301 ttcagtcatt aaataaaatt ttgaatgttt aggatttact aaaagtgaac taatcatagg
     3361 aataactgta attgcaataa tataagagat tattaccgaa gcaacaatag ttataccaaa
     3421 acttttaaag aattttccta caattccact catatttgca ataggaataa aaatagctaa
     3481 aagcatagct gaaatagcta aaacagaaaa agatatctct tttactccct ctaaagctgc
     3541 ttcatatcta cttttcccta attcaagttt tttataaata ttttctatta caacaattgc
     3601 atcatcaatg ataattccta ttgataaagt taaagctgta agtgtcaaaa tatttaaagt
     3661 ttgattgctc caacccatta ttgctaaaac tcccaaaatt gaaataggaa gagaaatagc
     3721 tgcgatgatt gtaaaagtga aatttcttaa aaatacaaat acgattaaag aagctaaaaa
     3781 acaacctaaa attaagtcaa attgaacact tttataagtt gattctataa atgttgttgt
     3841 atcaaatagt aaatttatat caaaatcatt tgataaactt tttatgtaag gaattttttc
     3901 ttttactaca tttgctatat ttacttcatt tgcccctgaa atttttttaa cttgtaataa
     3961 aacacctttt tgttgattat agtttgcaaa agttctttca tcttttattg tttcttgaac
     4021 tgttgctaca tcttttaatc ttactccatc ttttattttt atattttcta gttgttcaac
     4081 atttattgca tctgagtcaa ttgaaatatt taattcttct ttttcttgaa caactcttcc
     4141 tccatctttt ttgatatttt cttcatcaat ctttaaagct agttcattta aatcaagatt
     4201 atatttactc aaaagagttg tatttggata tatttttatt attttgtctc taaaacctgc
     4261 aatttcaact ttcccaacac cttcaatact ttgtaaaata ggttttacta cttcatttgc
     4321 gtgaagcatt aatttatcaa gattatcaag ttttgttgat aaaaaaagag ttattattgg
     4381 agctgaacta cttgagaatt tctcgattat aggtttatca gcttcttttg gtaaatctac
     4441 tgttgaaacc ttgtctctta catcatttgc agcttcttca acaggtttac ttaactcaaa
     4501 ttgagcaatt acaattgatt gattttttga agtatctgat cttattatat caattccaga
     4561 aataccactt atagcttctt ctattttatc agttatttta ctttcaataa tttcagttga
     4621 accttggtca tatgtagtta ttacactaac aacaggataa tcaacatttg gcaaaaatgc
     4681 aattggcatt ttttgaattt gtgtatatcc aaagaaaact aaagcaaata caaacatcaa
     4741 agttgtaatt ggtcttgaaa tagcaatttt gtacatatta gtttcctttt attattaatc
     4801 catcaccaaa attgccaatt tttaaatcaa ctccataagc ttctgcattt aattttttct
     4861 cattatttaa tgctggataa attttataga tttcaacaca agttttatta tcttctttat
     4921 ttgaatttaa acaaaacata tcaccagctt ttacatcttg agcaaatttt gaatcaaatg
     4981 ctaataaaag ttttttttca tttgaaacaa gttttaataa agctttttca ttattatttg
     5041 acatatcacc aacttctata tttttttcag aaattacacc agaaaatgga gcaattattt
     5101 tcatttttga tagttttgct tcatttaaag ttattaaatc ttttgcactt tttaactctg
     5161 attccaattt atctaagcta tttttatcaa aaacttctgc acttttttta tatctttcat
     5221 attgagttaa taaaaattta tattcatttt ttgagatttc aagatttgct ttttcttctg
     5281 aatcatttag tgaaagtaaa acttcacctt tttttacttg atttcctata tctgtattta
     5341 ttttagaaac aattccagat gttgaaacat ttaaagaggc ttcatttaat gcttttactt
     5401 cataagttgc ataaacatca gcaaataaaa tatttgttag aagtattatt ataagttgta
     5461 tttttttcat tttattcctt tataagtgtt aataaatcaa ttccaagtgc gaaagcaaga
     5521 ttggcttttt ttagttcaat atcattttta gctaagatta ctcgatagtt tgcatcttgt
     5581 ttttttgtaa gttcagttaa atattcagta taacttatca aatttgcatc aaatcttttt
     5641 ttactaaatt cataagttgt atttgtagct tcaagccctg atatcgcact atctaattta
     5701 acttttgaag attctagtga ttttaaagct agttttcttt caatttgaat agatttttct
     5761 ttataagcaa tctctttatt taaagctaaa gcttctaatt gactagcttc tttatctttt
     5821 gaaatttttc caaaatcaaa gattggaaag ttgatttgta gcattatttg attattgaat
     5881 ttatcattat atgtttcatc ataatgcaaa tattcttgtt tttttaaaga gttatttatt
     5941 gagattgttg gtaaatagtt aaaaccttca gaagtatatt ttacactttt tgcttcaagt
     6001 ttttttgctt caatatcaaa cctatctttt tcatcataag ttggttctat caacttatca
     6061 ttatcttgtg gcaaaatgtc aaaacctgtt aaaagagata gttgtaaaat agagttttct
     6121 aaatcaattt ttaaagtttc aatatcatat aaagcttctt tttttgaagc aattaaagct
     6181 tgaagtttat cttttgtttc aaggtcattt tttactaaaa tttcaaattt ttttatttga
     6241 ccatttaatt catttatttt gtaatttata acatcaatag cagattttgt attttgatat
     6301 gaaaaatatt gttttattac ctctaacata atctcttgct ttaaatattg agtttttagc
     6361 tgttgagatt cgtgtaaact ctttttagat aactcattat tttttattct ttcaccatca
     6421 tataaagtat atgatgcttt taattctgca taagctatat cttctggttc tgttttcaaa
     6481 acttttgaat tattttcata agctccaatt agattaaatg ttggataatt atcttttgtt
     6541 gctgattcat actgtttctt tgacatttct tgtaaagctt gttgggcttg ataattctca
     6601 tttgttactt ctacactatt taaaagttct tttaatgata tagcatataa cgaagtagat
     6661 attaaaaaag atataaatat atttttaaac ataaaaatcc ttttatcttt ttagctgatt
     6721 tgttgtttca ataagatagt ccataattgt ctcttttaag ttatagtcat ctattattaa
     6781 agagtggtag tacattccat caattgttgc aagaattact tttatagctt tttttgagtc
     6841 ttcttttaaa aatccttttt ctatttcttc atcaaaaatc ttttcaataa tttcatacat
     6901 attaatatag gtattttcac aacttttcat ctcatcttta tatttaggat gaagatacaa
     6961 atgtattgac tcaaacataa tctttctagc gtcaataaat attttttctt cttcatttaa
     7021 aatcaaagca aaatattcaa ccaatttttc taggaaatta cttttttttg caatattttc
     7081 ttttattatt tctacaaatt caatatcttt tatttttaga gtttcaaata ttagtttctc
     7141 ttttgattta aaatagtagt agaattgtcc ctttgacata ttcaattctt ctataaattt
     7201 atttaaagaa aattcgacaa taccttcttc tacaagcctt tcataagcta aggcacatat
     7261 ttctaatctt ttttcttctg cattaataat ttttggcatt ttttaatctt tttatatgga
     7321 ctgatagttt tttaaactat cggtctattt taactataaa aaatttaaat taaaataaat
     7381 tttttgcatt taacaaaaaa tagtacattt atattgcaga aaattttcac aatttaagat
     7441 aaataaacta ggagttgttc ctgaaaagaa tttaaactct ttgatgaaag atgattggtc
     7501 atagaagtta ttttcaaaaa taatattttt aaagttgata ttattttcat tagattttat
     7561 tagttttaaa gtgttataaa atctatttac tctttctatt gattttggag caagtcctgt
     7621 aaaatctttt acttttcttt gaatttgtct aatagataat ctattttgat tataaaaatt
     7681 ttccaaattt ggattttttg taagttcata aagatttgat aacaaactat cttcttgcat
     7741 attttcaaat attttaaata aatattcatc aagagtattt aaagaagata aattactacc
     7801 ttttaattca aatagtaaat caataattga aacatcaaaa tttaaagaca actcttttat
     7861 ttcataaact ctatcttcaa gttcacaaac aggtattcca aaaagtttat aaaaaactcc
     7921 aggatacaaa gaaatatcaa cataataaat atttgattct aagtttagat tgtgtctatt
     7981 taatgttgga ggacatacat aaataccttt ttttaaagta acatctgaat aagagatatt
     8041 tttttgtata tctataatca ttagtaaaca tacattgtca taaggtagaa taattttttc
     8101 tttctctatt acatctaacg tttcgttgta atcaacaaac caataagatt ttacccattt
     8161 ttgtagtttt atatttggtt taaaagtttt aaattgaaac aaatttcatc ctttataaaa
     8221 aagaatttta atacttttca tttctcttta gctttttaat ttgtatattt tatatacata
     8281 aatgtcgttt taatactata caagtaactg ggtgattatt tataatttca ctgaaactaa
     8341 ataataggtt tttagttaaa taattttatt tgaggagcaa aagttgaatt acaaaagatt
     8401 atcaaaattt gggatgaaat ctttagtttt attagcggcc ttacctttat ttgcagttga
     8461 tgcacaaaaa ggtaaagaag ttattgaaag taaatgtatt gcctgtcata caggtgattt
     8521 aaaagatggc ttaagtcgta tttctgatca aagaaaaaca ccagaaggtt ggtatatgac
     8581 agtaaaaaga atgcaaaggg aacatggctt atctattaca aaagctgaag aaacagatgt
     8641 tattaaatac cttgcagatt atcaaggttt gactcctgat gaaataaaac cttactctta
     8701 tgttttagat aaaaaaccaa atgttcaaga agagggtaaa gatgaattat taactcaaat
     8761 gtgtgttaga tgtcactcag aagcaagaat tggtcttcaa agaagaactg caaatgagtg
     8821 gaatagttta gtaaattatc acgttgctca atttccttct tttgaagttc aagcacaagc
     8881 aagggacaga gattggtttg gtgtagctca aaatgaagtc gtaccttatt tagaagaaaa
     8941 ttttggaaaa gataaagaaa aatttgagaa atataaaaaa tcattaaaaa attatgaatt
     9001 acctaaaaaa tgggtaatgt ctggacatac tccaataatt ggtgatttta cagctaattt
     9061 aacattaatg aaaagtgcag atgaatctta tggaatgctt attgattata aatatgcaaa
     9121 tggaaaagag tacaaaacaa ctggtgttgc aatagtttat ggaaaaacag aacttagagc
     9181 ttcttttgaa atagatggag ttaaatatag acaaatttta catattgacc caaaaacaaa
     9241 tactcttgaa ggaagaatgt ttgaagtact tcatcctgaa aatggttcta ctttagtagg
     9301 aaaaacaaaa gattcaaaag agacaacatt agtagcagtt tatccaaaag ctgtaaaagc
     9361 tggagaaaaa tctactattt caattgttgg tacaaattta gttggggatg ttaaattacc
     9421 aagtagttta aaagttttaa aaactattaa acacacaaat aatgaaattg tattggatgt
     9481 tattgcagat aaaaatgtaa aaacttttga tagaaatatt tcaattggta caaaaacatt
     9541 taaaaatagt ttagttgtat atgacaaagt tgattatata aaagttactc ctgattatgc
     9601 aatttcaaga attggtggag aagaaggtaa agataaaatc ttaaaagagt atgcaacttt
     9661 tgaagcaatt ggatatttaa atggaaaaga tggcaaaaaa gagacagcag atgatattga
     9721 attaggtgta ttacctgcaa catggagttt agaagcttac gatgaacaag cgcaagagga
     9781 taaagattta gaatatgttg gtcaaataga tgctaataca ggaaaattta ctccaagtgt
     9841 agctggacca aatgaacaaa gaaaattgat gacaaataat gctggaaata taagtgttgt
     9901 tgcaacatat aaagatggaa aaaaagagtt gagtgaaaaa tctcatatga ttgtaacagt
     9961 tcctaaattt gtgaacccac caattaatta agaatttatc atgagtatca ataactataa
    10021 tttaataaaa acaaattacc atattttaga aatagattca aaagaatttt tatttcatat
    10081 accaacttct tcagtttttg agttatcaac tgaaagtgca aatcttttaa gaaagatgga
    10141 aaacaaagaa gagataacaa aagatgaaga agagatagtt gaagagttta aagagttaaa
    10201 tattatagga agcagatttt ttgtaaaaga agaagataca aaaatagaac attttcctgc
    10261 aaaagctcta gttttaaatg taacttcagg atgtaatctt agttgtacat attgctataa
    10321 agcagattta acctctttaa aaaatagtgg tcaaatgact tttgaaattg caaaagatgc
    10381 tattgatatg ttttataaag aatctccata tttaaaagag tattcaatta ctttttttgg
    10441 aggtgaacct ttgagtaact tacctttaat caaacaaatt attgcttatg caaatgattt
    10501 ttttgaaagt aaaggtttaa aaattggtta ttcgatgact tcaaatgcaa cacttttaac
    10561 tgatgaggtt attagatatt tacatgaaag caaagttgat ttaactatta gtattgatgg
    10621 tccagaatct cttcataaca aaacaagagt atatgaaaat ggaaaaggaa gttatgaaaa
    10681 agtagctaaa aatgtggcaa aactattgga tatttataaa aatagaacag taggtgcaag
    10741 agttacttta acaagaggag taacagatgt aaaaacaatt tggaatcact taagatatga
    10801 cttaaaattc aaagaggttg gttttgctcc tgcaacttca ggcgataatg acttttttaa
    10861 tttaagtgat agtgatttga aaaaagtttt tgtaggattt aaagagctag gtgaagatta
    10921 tataaatgag gcaattaaag gtaattttaa tggtttttca aatcttcatc gaacagtaat
    10981 tgatattcat gaaggaagaa agaaaaaatt accttgtgga gctggagttg gattactttc
    11041 tgtttcatat aaaggtgata tagatttgtg tcatagattt acaggttctg attatccatc
    11101 ttttggaaat atagaaaaag gtcttgataa aaaagcttta gggagttttt tagaaaaaag
    11161 agcaaatgaa aaagatacaa gttgccaaac atgtagaatt agaaatctat gtgcaggtgg
    11221 ttgttatcat gaaagttata tcaaatatgg aacacctgaa aaatcagtgt tgcattattg
    11281 tgatgatatg agaaattgga ttgattttgc agtagaagca tatataagaa taaaagcaaa
    11341 aaatccagaa ttttttacaa aatattttaa ataaggaaaa gaaaatgaaa catttaaaac
    11401 caattacacc aaaagctaaa cttttagaag aggctttaaa agagggaaat gcaaatgaag
    11461 tagttgcaat gtcaagtgtt gtgggatgtg ttacaacatt tgatccaggt tgggaagtag
    11521 atagtgatgg tggagttgct agtctttgtc aaccaatgga agcagattta tatggatgtt
    11581 cagatccttg ttggtggcca actcaagttc ctgatacttc ttctagttat aaaaaatgga
    11641 gtgaaaaagc tcctgcaaca aaagatgact ggcgagaatt agaaaatgta tatccaaaaa
    11701 tgtaaataga aaggttgtta gtatgttaaa taaaaaattt ataaaaagtg gtttaggatt
    11761 attaagcttt tcattaattt tatcatcaag cttaagtaca aacttaaatg cagcaaatgt
    11821 taaattaaaa tcaaatcacg attatttggt tactgttaca agaccaaata atattgcttt
    11881 agttgattta gaaaaaaatg agatgataaa tgagtgtaaa atagatgaag ctttctctcc
    11941 aggagcaata gttttatctc caaataataa agttgcattt gttttaggtg aatatggaga
    12001 agaagttgct ggttatgaaa tagaaacttg taaaaaagta tttcatactt ctttaactca
    12061 aggaaatatt agagcaaaat ctctatttgg tttatcagtt aatgaagatg gaacaaaagt
    12121 ttatgcaatt tataatagaa cagagatgtt aaatgataga tataaagttt tacctccata
    12181 tttttcagtt tataatgtag ctgatggatt agatgcaaaa ccagttaaaa gttttgagat
    12241 gccaagacaa acaacagttg tttcaactgg aaaagatgga acagtttatg tagttggttc
    12301 tgatttatat aaagtaaatc caaaaagtgg tgatatagaa gttgcaaaaa aaatagttaa
    12361 atgggggaaa gagggatata gtgaccttga ttctgctgca aactatataa taggacaaca
    12421 aacaggagat ttaacagctt tatatgcaac agtaaaatat gatgacccaa aaaatccatc
    12481 agaggaagaa ggaactacat attggggaat tacaagtgtt gatttaaata caggagaaat
    12541 aattcaacaa gaaatttcag aatatgaaac tttgatgttt acagcaatta gaagtccaaa
    12601 agatcaaaat atcttatacg gagttttaaa tgatttaaca aaatttgata taaaagaaca
    12661 aaaagtgtta aaaagagttg taacagatca tacatattat agtgttgttc catcagtaga
    12721 tggtgaaaaa ttatatcttg gtggttgttt aaatgatatt gcaatttatg atgcaaatag
    12781 tttagaaaaa cttggaaaca ttaaattatc tggagatatg ggttcagctg ctcttcaagt
    12841 atttaaaaca aaataggcaa actttctagt atgtttaaaa atattatata tcctctctta
    12901 aagaaaaata agagagggtt ttttgtcatc ttcttttttt ctattcttgt ctctcttggt
    12961 ggagcagttc aaccatatat tatgcaacat ataattgata atgctatttt agcttcaaat
    13021 ataaatcagc ttattttttt agtttctatc tcattctttc ttactgtttt tgttatgata
    13081 ataagttata taaatgagat ttattacaca aagaattcaa tgaatatttt atttgaattt
    13141 agaaaaatag tttttaataa actattttta catgataaaa cttttttaaa caactatcat
    13201 tcagcagatt tgatgtcacg agttcaaggt gatattagtg aacttcaaag attttataca
    13261 gatagtgtgt tctcactatt ttcaactatc attagtcttg tatttatctg ttttattgtc
    13321 tattcatata atataaaact aatgatactt atacttatat ttttgccaat agagtttttt
    13381 tgtttaaaac ctctatatcc acatattcaa aatagcacaa aaactatgag agaatcaact
    13441 tcaaatattg gaaagttttt tattgaaaat tttagatata tgttaactat aaaaaatcta
    13501 ggagcaaaag aacaaacttt agaaaaactt gattttattc aagatgatta taaaaatgtt
    13561 gtaataaaaa ataaaaaaat caatttactt ttttcacaaa tcccagcatt tatttcactt
    13621 cttggaaaaa ctatcattgt atcttatggt ggatatttga cgattaaagg tgaattgaaa
    13681 attggagaac ttttcgcatt tttgacatat tttactatga ttttagctcc tgttcatacg
    13741 atattaggag ttataaataa ttttccaaaa gtaaaagtaa gtcttaatag agtgcttgaa
    13801 atattaccaa aagagaaaga taatatagaa ttaaaaacaa caaattttga tttaaatata
    13861 aaaaatttag agttttctta ttcaaacaat aaaatatttg aaaatctaaa tctttttata
    13921 aaagagagaa gtaaaatcgc aattattgga aaaaacggtg caggtaaaac tacctttgct
    13981 gatttacttt gtggatttct aaaagctaat aatggagata tttttatagg gaatgaaaaa
    14041 ataggagaga ataattatat aaatttttct tcatatttag taaagttaga acaaactcca
    14101 attatttttg atgatacttt aaaaaacaat cttcttttag caaaaaacag tgcaagtgaa
    14161 gaggagttaa tagattgttt gaaaaaaaca ggtatgtgta agtggtttag aaatttgcaa
    14221 aaaggtttaa atacaaatct tttagaatca ggagcgaatc tttcaggtgg tcaaaaacaa
    14281 agattggctc tttcaagatt gattttacta aatccaaaaa tcataatttt agatgaattt
    14341 acatcttcaa ttgatgaaaa agatacttct tggttttatg aaaatatttc aaccattttt
    14401 ccaaactcaa ctattattgc aataacacac aacttaaata tgttgagcca ttttgataaa
    14461 gtttatttac ttgaaaataa aactttaaag gagtataaaa atgtctaaag aggtttttgt
    14521 tgcattaata gatagtggtt gtaattttga aacttatgaa aaaattgcca tacatataga
    14581 aaacaataga ataaaaatca aaaaccaaaa taatataaat tttgaacatg gaaatgttat
    14641 tggaaatatt ataaaagatg aaaatataaa tatttatgat attcaagttt ttaatgaaaa
    14701 tctatcaaca actcctcacc atatttttgg tgcattaaat tatctaaaag ataaaaaagt
    14761 tgatgtaata agtatgagtt taggtctaaa aacaaactat aaagagattg aagagttatg
    14821 tcgtgaattt ataaaaaaag gtgttgtaat catctcttct tatccaaaat ctgggcaaga
    14881 gtttgtttat ccagcttctt atgaaaatgt tataaaagta acttcagaag gaaaatgtat
    14941 ggatgataaa gtagttgttt tagataaaga aaaactattt tttggtgcaa atcctttttc
    15001 aactgtaaaa aatgttgctg gttcaagtgt tgcagttgca aaatttacaa aagagttttg
    15061 ctcttatata aaaaagggtt ttagcaaaat tgagataatc gaagagtttt caaaaaggat
    15121 tattaagtga atagtaataa aaaaatagtt gtacttggtg ctggaattgc aggtagttct
    15181 actgctattg gacttaaaaa attaggtttt gatgtaactg ttatttacaa aaaaagacca
    15241 tttactgctt atgaaggatt tagccaaaaa acaaaagagg gacttatctc attaggttgt
    15301 ataaaggctt caaaactttt agttgaacaa tctttacgaa actcaaattg ggcgagtaaa
    15361 acgcataaag taaattatga atttgttgta aatagaaata tatttgataa aactttattg
    15421 gaagatttaa aagagtatca aataaaaatc attgaagcaa aagttattgg ttcgattgat
    15481 tatttagatg aaaaaccaaa aattgtttat aaaatagatg aaaaaaaata tgatttaatt
    15541 gcagattttg ttattgatgc aagaggaaga tttacacctt ttaaagatga atatatttgt
    15601 ggtccaaaaa gtttctcact tttacaagag ttagaacttg aagatataaa tgaaaatcaa
    15661 acttctattg attcagtaaa agatggttgg atttggcaag cttatgttgg agataaaaga
    15721 ggttatattc agttttcttg tgatgaagaa ctagcaaaca aagttaattg ttttgaggat
    15781 atgctaaaaa ttttgcaaga acaaaatata gaactttgga gtttaaataa ctataaagtt
    15841 gttggaaaat tagtaaaaag agactctttt tgtaaaattc ataaaaagat aataaataac
    15901 aagatgatgt tagttggaga tagcgcatca agtattgacc cactttctgg aaatggcgct
    15961 tttcaagcta tgagtatgtc aagtattact ccatttgtaa taaacacaat tttaaataaa
    16021 agtgaaatag aacaaaaagt agcaattgat ttttataaaa gtagagtaga gtttatcttt
    16081 gataagttta caaaagttgg aaaagagttt tatatattag aaaaaagatt taatactcct
    16141 ttttggcaaa atagacaaac ttggcctcaa gataaaaatg aattagaaaa aaaagttcca
    16201 agaatagaaa aaaaagcagt tgtaaaagat ggttttgtaa atgaaagtga agtagtaatc
    16261 acaaaacata atccttttgg tgcttgctat tttggaaata ttgaaattat agatttagct
    16321 aaatattgtt tagaaaacag ctttgaaaaa tctttggatt attttgatat tttttgtaaa
    16381 gaaagaaacg tcccacttca agtaggcaat tctttaaaga attggtgtat aaaagaagaa
    16441 atcttaggat aaaaagagta ttaataactc tttttatctg cactttttaa gaactctttt
    16501 tggaatctta ctattttgtt tcttcctgtt tcttttgctt catataaaga tatatccgca
    16561 tatttgatac atttccaaat ttgatcagca tcatcaggga agaaagagta tccaatactt
    16621 acagttttac taaatgcttg tccattataa ttaaatacaa gttttgcaaa ctcttgattt
    16681 attttcgttg caagttctct tgcactagtt tcagttggat ttttcataat aattaaaaat
    16741 tcttctcccc caaatctaac aataaactca ttttcagaaa tagaagcttt catcgtatct
    16801 gataattttt gcaatattgc atcacctgca tcatgcccat aagtatcgtt tatcattttg
    16861 aagtagtcaa tatctaaaaa cataatcgca aattttgaac cattttgtgt ttcatgaggt
    16921 aattttttct caataaattc atctaaatat ctacgattat agagtcctgt tagtccatca
    16981 actaaatttt tttctcttaa tgcatccatt aaaagtttac tttctaaaat aggttttgtc
    17041 tcttctaaat attttttgat tattcctatt tgatatttag tattttgtaa actatcttta
    17101 tctttacaaa ctatatgaat aacaatattt ttttgttcat ttattaaaaa tggaatacaa
    17161 atatgatttg tctctcctga acaatttgca attctacaaa tctcagggaa gttttctgaa
    17221 gagacaatcg tatttgttct ttctgctcta caaccagctt ttataccttt tgaaatactg
    17281 caacaaggtt tttctacctc ttttactggg tatattgttc ttctttcatc ttttattaag
    17341 tctgtttcaa aaatataaaa agattcaata tttagtttat ttttcaaaac ttgaattaat
    17401 ctataaaaaa tatcttcttt tgttaaatct gtttcgatag tttttttata gttgtaaatt
    17461 tcagttatat cttcaataat ctctttggct gttaaaagtt tatcattact aaaaatcgta
    17521 gctctattat gaacaaatga tgtaagattt ttttcaatac ctgttaagac tgtttcaagt
    17581 ttttcaatta attcatttaa ccaaattgaa gcttctttat cctcttttaa cacgccttct
    17641 ttaactctaa ctgaataatc accttcatga acttgtttta aagtttcagt tatagaatca
    17701 aatgagtttg taaaaggagt tatctttttt cttaaatata ttaaaatgag gattaagaaa
    17761 actgagattg tcgcaacaac atttatcaat ataacaatat ttgaaattct atcttcttga
    17821 atatcaaaag ttaaagaaat agcacctaaa acttgccctt cttgtgcatt atgacatgac
    17881 atacaattag gtttatcaag agatgaagct gtatatggaa tagtgattct taaagtagca
    17941 tcttttaaag actcatttac aataaccttt tctttaccat tttttagtac atctaaatcg
    18001 atattatctc ttgctttttc tgttgctaat aaagagtttc caaattgttc actaacactt
    18061 tttgacctta caacccaaag ttctttaatt ccttgtaagt tatttaagct acttaaaaaa
    18121 gtatctcttt gatgcatagt accatttatc atatggctag ttaaagaatt ttttactaac
    18181 tgggcagtta aataggctct tttttttgct ccatcgtatc cactatgtct cgagccaagt
    18241 gcaactaata ttattataat tacagcaagt atcgaaatca tagtaaaaat tataagagta
    18301 atttttttat tcgagctcat attttcccct tcttatttct aaaatataat agcataaaat
    18361 tatttttgtt ttaataattt ttatatatat ttataaaatt ttgaaagctt cttctaaatc
    18421 taaagttcct tcataaaatg ctttacctac aataacacca gaaatatttc catttgcttt
    18481 acaatttatg atgtcttgaa tatcttttac tccaccacta gcaattgtgt caacactact
    18541 tgcaagagcg atagactccg taaattcaac atttactcca caaagcattc catctttact
    18601 aatatctgta caaataatcg cttgaacacc tgcatttgca aactcttttg ctaaatcagt
    18661 tgctttcata gttgaaactt ctgcccaacc ttcaactgca accattccat tcatcgcatc
    18721 aattccaaca gcaattggat attttgaagc catttttttt acaaaaattg gatcttttac
    18781 tgcaattgaa ccaagaatca gtctatcaac accaagttca aggtacattt tgatagtttc
    18841 ttcatctctt attccaccac caagttcaat ttttaaattg caattttctc taattttttt
    18901 gatttgctct aagtttgcag gttttccagc aaatgctcca tttaaatcaa caatatgaac
    18961 ccattttgaa cctaattctt caaatctttt tgcaacttgc caaggctcat cagaatagat
    19021 ttttgcacta tccattaaac ctttacttag tcttactgct tttccatctt ttaaatcaat
    19081 cgctggtaat atatccatta acaaaatcct taactacata aattttctat tgtttcttct
    19141 attgttttaa atttgaattc aaatcctaaa ttcaataatt tttttggaat tgcactttgt
    19201 ccatctgtta aaacacgtgc tccttcacta aaaataagtt ttaaaacaaa ctctggtact
    19261 ggaagtatag taggtctttt tagtgttttt cctaaagcaa gagttagacc tttatttgtt
    19321 gttggagttg gtgctgttag gttaaatact ccatcataat cgttctctat aacgaatttg
    19381 taagcattta ataaatcatt tatatgaata aaagaaaaag cttgttttcc acttcctatt
    19441 gttccaccaa gaccaaattt aaatggagta atcatttttt gtagtgctcc accatctttt
    19501 cctaaaatta ttccaaatct aaaaatagca acttttgttg tcccattttt tacttttaaa
    19561 gcttcttttt cccaatcttg acaaagattt gataaaaaat catttgaaaa agagccattt
    19621 tcatcataaa ttgatttatt atcatagatt ccaacagcag aagttgaaat aagtaatttt
    19681 ggtttgtttg aaatactact tattgcattt actatttttg aagttgtatc aattcggcta
    19741 gaataaagaa gttttttata agattcactc catctattta tgatatttgc acctgcaaga
    19801 tttatcacaa tatcagtaga atttagtact tcttctaatt tacttttatt gtttaaaata
    19861 tctcttgata aaggtacgat tttatatcca aagcttgaaa aaaagtttgt taaacttgtt
    19921 cctacaaatc cattagcacc actaattgca atagttttca tacaaaatcc ttttttttaa
    19981 attaattaag gttcataaaa ttcttcaaaa ttttcaatcc attatcgtga gatttttcag
    20041 gatgtggttg aaaaccgtaa atattatctt tgtttactgc acttgcaaat tcatatccat
    20101 aagttgtttt accaattata tttttttcat ttgttactgc gtgataagag tgaacaaaat
    20161 ataaatatgg attatggagt ccttcaaata aagggtgttc tttatttaca attgtattcc
    20221 aacccatgtg tgggattttg aagtcttcat tcatttttga tttatcaaat tttactacaa
    20281 ctccatcaat taaacctaag ccatctgtat gaccaaattc ttgtgaactt tcaaataaaa
    20341 gttgcattcc aagacaaatt ccaatcattg gttttccact ttttgcaaac tctaaaatag
    20401 cttcgttcat acctgttttg attagatgtt ccattgcatc tttatatgct ccaacaccag
    20461 gtaaaataac tcgattaaaa ttctttaaat cttcaggttt tttaacaata gttgcctttg
    20521 catcaagtaa atgacatgca ttataaacac ttgccaaatt tcccatatta taatctatta
    20581 ttccaatcac tattttagtc ctttaaatta gttccaattt caataaatta tactaaagtt
    20641 ttgcatcagc tagggttaaa gaaaataata tttgattatt ttttttctcc aaagcttttt
    20701 ttgcttgaat tattgtagtt ccagttgtga ttaagtcatc acataaaatt acaaatttat
    20761 ctgagaggtt atttatttga aattttcttg agtttttttg tctaaattcc aaattttttc
    20821 ctgcatattt aactatattt gtagctttta atgagttgta ttttggtttg attatttttg
    20881 attttagatg ttttgccaag attgcgcagt gcgaaaaatc atgtcttgta tggtcatcaa
    20941 taggaatggc taaaacttca gaaggaaaat caaaatttaa tgcaaattta gcaaaagata
    21001 gttttgccaa aatattaaaa actctatctc cataaaaata gtattttgag tttatcaaat
    21061 cttcaagttc tgataaagag taaaaagagt agttgaaaaa tccatcttct atttctcttt
    21121 tatgaaaaga gggctcaaga agtgtaattt gacaagtttt acaaatgata gaaaaagata
    21181 acttatcaca acttatacac ttcatatatt gcctttatta aaaaaaatca aagtatttag
    21241 tttaaattta tttttttata catctaatat tcataccatc tgctctatct gaattagaat
    21301 tactcatacc tatatatgta tctgaaaaat taaaatttct tgcttttgct actccatttt
    21361 cactaattgg agta
//
